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clonidine and Parkinson Disease, Postencephalitic

clonidine has been researched along with Parkinson Disease, Postencephalitic in 1 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Parkinson Disease, Postencephalitic: Parkinsonism following encephalitis, historically seen as a sequella of encephalitis lethargica (Von Economo Encephalitis). The early age of onset, the rapid progression of symptoms followed by stabilization, and the presence of a variety of other neurological disorders (e.g., sociopathic behavior; TICS; MUSCLE SPASMS; oculogyric crises; hyperphagia; and bizarre movements) distinguish this condition from primary PARKINSON DISEASE. Pathologic features include neuronal loss and gliosis concentrated in the MESENCEPHALON; SUBTHALAMUS; and HYPOTHALAMUS. (From Adams et al., Principles of Neurology, 6th ed, p754)

Research Excerpts

ExcerptRelevanceReference
" Clonidine hydrochloride, an antihypertensive drug believed to directly stimulate brain norepinephrine receptors, was administered to a group of patients with relatively mild Parkinson disease and coexisting essential hypertension and to three patients with Parkinson disease manifesting the "on-off" response to levodopa."7.65Clonidine in Parkinson disease. ( Marsden, CD; Parkes, JD; Tarsy, D, 1975)
" Clonidine hydrochloride, an antihypertensive drug believed to directly stimulate brain norepinephrine receptors, was administered to a group of patients with relatively mild Parkinson disease and coexisting essential hypertension and to three patients with Parkinson disease manifesting the "on-off" response to levodopa."3.65Clonidine in Parkinson disease. ( Marsden, CD; Parkes, JD; Tarsy, D, 1975)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tarsy, D1
Parkes, JD1
Marsden, CD1

Other Studies

1 other study available for clonidine and Parkinson Disease, Postencephalitic

ArticleYear
Clonidine in Parkinson disease.
    Archives of neurology, 1975, Volume: 32, Issue:2

    Topics: Aged; Antiparkinson Agents; Clonidine; Female; Humans; Hypertension; Levodopa; Male; Middle Aged; Pa

1975