clonidine has been researched along with Palsy in 10 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this paper we describe a typical case of tetanus and report our observations with the centrally acting alpha 2-adrenoreceptor agonist clonidine." | 7.69 | Autonomic disturbance in severe tetanus: failure of parenteral clonidine to control blood pressure. ( Brown, JL; Mathias, CJ; Sinding, H, 1994) |
| "Selected examples from three series of isomeric (alkylthio)-1,2,4-triazoles were prepared and examined for anticonvulsant activity versus strychnine-, maximal-electroshock-, pentylenetetrazole-, and 3-mercaptopropionic-acid-induced seizures in mice." | 3.69 | 5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents. ( Dalton, CR; Dudley, MW; Kane, JM; Kehne, JH; Ketteler, HJ; McCloskey, TC; Miller, FP; Ogden, AM; Senyah, Y; Staeger, MA, 1994) |
| "In this paper we describe a typical case of tetanus and report our observations with the centrally acting alpha 2-adrenoreceptor agonist clonidine." | 3.69 | Autonomic disturbance in severe tetanus: failure of parenteral clonidine to control blood pressure. ( Brown, JL; Mathias, CJ; Sinding, H, 1994) |
| "The efficiency and duration of action of a single oral dose (8 mg) of tizanidine in patients with spinal cord injuries were determined by studying its antispastic, cardiovascular and sedative effects along with its pharmacokinetic profile in five tetraplegic and five paraplegic patients." | 3.67 | Pharmacodynamics and pharmacokinetics of the oral antispastic agent tizanidine in patients with spinal cord injury. ( Baker, H; Desai, P; el Masri, W; Frankel, HL; Luckitt, J; Mathias, CJ, 1989) |
| " The study consisted of 4 parts: I, double-blind cross-over trial at maximal dosage 10 mg/day in 13 patients; II, open trial at maximal dosage 32 mg/day in 10 patients; III, long-term medication at dosage 32 mg/day for 6-15 months in 4 patients; IV, single dose (12 mg) administration in 3 patients." | 2.65 | Antiparetic and antispastic effects induced by tizanidine in patients with spastic paresis. ( Gransberg, L; Knutsson, E; Mårtensson, A, 1982) |
| "Selective role of spasticity was estimated in clinical pattern of motor disorders in groups of the patients with different disorders of muscular tonus with the same degree of paresis." | 1.30 | [Disorders of muscle tonus and their treatment with sirdalud in patients in the early recovery period of ischemic stroke]. ( Beliakov, VV; Burd, GS; Gekht, AB; Iaish, F; Selikhova, MV, 1998) |
| "Twelve spastic patients received single oral doses of a new anti-spastic drug DS103-282 (Sandoz) 6 mg, baclofen 20 mg, and placebo on three separate days." | 1.26 | Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity. ( Hassan, N; McLellan, DL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kane, JM | 1 |
| Staeger, MA | 1 |
| Dalton, CR | 1 |
| Miller, FP | 1 |
| Dudley, MW | 1 |
| Ogden, AM | 1 |
| Kehne, JH | 1 |
| Ketteler, HJ | 1 |
| McCloskey, TC | 1 |
| Senyah, Y | 1 |
| Knutsson, E | 2 |
| Mårtensson, A | 1 |
| Gransberg, L | 1 |
| Hassan, N | 1 |
| McLellan, DL | 1 |
| Brown, JL | 1 |
| Sinding, H | 1 |
| Mathias, CJ | 2 |
| Zenz, M | 1 |
| Gekht, AB | 1 |
| Burd, GS | 1 |
| Selikhova, MV | 1 |
| Iaish, F | 1 |
| Beliakov, VV | 1 |
| Rösche, J | 1 |
| Gerstenbrand, F | 1 |
| Lorincz, A | 1 |
| Ludin, HP | 1 |
| Ringwald, E | 1 |
| Luckitt, J | 1 |
| Desai, P | 1 |
| Baker, H | 1 |
| el Masri, W | 1 |
| Frankel, HL | 1 |
1 trial available for clonidine and Palsy
| Article | Year |
|---|---|
Antiparetic and antispastic effects induced by tizanidine in patients with spastic paresis.
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Double-Blind Met | 1982 |
9 other studies available for clonidine and Palsy
| Article | Year |
|---|---|
5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents.
Topics: Animals; Anticonvulsants; Cerebellum; Cerebral Cortex; Chlorides; Electroshock; Flumazenil; Male; Mi | 1994 |
Analysis of gait and isokinetic movements for evaluation of antispastic drugs or physical therapies.
Topics: Cerebral Palsy; Clonidine; Electromyography; Gait; Humans; Motor Neurons; Muscle Contraction; Muscle | 1983 |
Double-blind comparison of single doses of DS103-282, baclofen and placebo for suppression of spasticity.
Topics: Adolescent; Adult; Aged; Baclofen; Clonidine; Double-Blind Method; Electromyography; Female; Hemiple | 1980 |
Autonomic disturbance in severe tetanus: failure of parenteral clonidine to control blood pressure.
Topics: Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Humans; Hyper | 1994 |
[Clonidine for intrathecal pain therapy].
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Back Pain; Catheters, Indwelling; Clonidine; Fem | 1996 |
[Disorders of muscle tonus and their treatment with sirdalud in patients in the early recovery period of ischemic stroke].
Topics: Adult; Aged; Brain Ischemia; Clonidine; Female; H-Reflex; Humans; Male; Middle Aged; Muscle Relaxant | 1998 |
Treatment of spasticity.
Topics: Acetates; Amines; Aminopyridines; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Clonidine; Cy | 2002 |
[Long-term treatment with an imidazoline derivative (DS 103--282) (author's transl)].
Topics: Arm; Clonidine; Female; Humans; Leg; Male; Multiple Sclerosis; Muscle Spasticity; Paralysis; Urinati | 1979 |
Pharmacodynamics and pharmacokinetics of the oral antispastic agent tizanidine in patients with spinal cord injury.
Topics: Administration, Oral; Adult; Blood Pressure; Clonidine; Drug Evaluation; Heart Rate; Humans; Male; M | 1989 |