Page last updated: 2024-10-25

clonidine and Organophosphate Poisoning

clonidine has been researched along with Organophosphate Poisoning in 2 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Organophosphate Poisoning: Poisoning due to exposure to ORGANOPHOSPHORUS COMPOUNDS, such as ORGANOPHOSPHATES; ORGANOTHIOPHOSPHATES; and ORGANOTHIOPHOSPHONATES.

Research Excerpts

ExcerptRelevanceReference
" Forty eight patients with acute organophosphate poisoning were randomized to receive either clonidine or placebo: Four to receive placebo and twelve to receive clonidine at each dose level."5.14A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning. ( Abeysinghe, C; Buckley, NA; Dawson, AH; Hettiarachchi, R; Jayamanna, SF; Karunatilake, H; Perera, PM, 2009)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perera, PM1
Jayamanna, SF1
Hettiarachchi, R1
Abeysinghe, C1
Karunatilake, H1
Dawson, AH1
Buckley, NA1
Liu, WF1

Trials

1 trial available for clonidine and Organophosphate Poisoning

ArticleYear
A phase II clinical trial to assess the safety of clonidine in acute organophosphorus pesticide poisoning.
    Trials, 2009, Aug-20, Volume: 10

    Topics: Acute Disease; Adult; Antidotes; Clonidine; Female; Humans; Male; Middle Aged; Organophosphate Poiso

2009

Other Studies

1 other study available for clonidine and Organophosphate Poisoning

ArticleYear
A symptomatological assessment of organophosphate-induced lethality in mice: comparison of atropine and clonidine protection.
    Toxicology letters, 1991, Volume: 56, Issue:1-2

    Topics: Animals; Atropine; Behavior, Animal; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Comb

1991