Page last updated: 2024-10-25

clonidine and Neuromuscular Blockade

clonidine has been researched along with Neuromuscular Blockade in 6 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Neuromuscular Blockade: The intentional interruption of transmission at the NEUROMUSCULAR JUNCTION by external agents, usually neuromuscular blocking agents. It is distinguished from NERVE BLOCK in which nerve conduction (NEURAL CONDUCTION) is interrupted rather than neuromuscular transmission. Neuromuscular blockade is commonly used to produce MUSCLE RELAXATION as an adjunct to anesthesia during surgery and other medical procedures. It is also often used as an experimental manipulation in basic research. It is not strictly speaking anesthesia but is grouped here with anesthetic techniques. The failure of neuromuscular transmission as a result of pathological processes is not included here.

Research Excerpts

ExcerptRelevanceReference
"Intubation of the trachea and mechanical ventilation are ubiquitous painful procedures in the neonatal intensive care unit that are poorly assessed and treated."2.49Sedation and analgesia to facilitate mechanical ventilation. ( Colby, CE; Nemergut, ME; Yaster, M, 2013)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Weber, V1
Abbott, TEF1
Ackland, GL1
Nemergut, ME1
Yaster, M1
Colby, CE1
Chen, YW1
Chu, CC1
Chen, YC1
Hung, CH1
Wang, JJ1
Yelnik, AP1
Broch, O1
Breucking, E1
Narimatsu, E1
Niiya, T1
Kawamata, M1
Namiki, A1

Reviews

3 reviews available for clonidine and Neuromuscular Blockade

ArticleYear
Reducing the dose of neuromuscular blocking agents with adjuncts: a systematic review and meta-analysis.
    British journal of anaesthesia, 2021, Volume: 126, Issue:3

    Topics: Adjuvants, Pharmaceutic; Clonidine; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Synergis

2021
Sedation and analgesia to facilitate mechanical ventilation.
    Clinics in perinatology, 2013, Volume: 40, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Benzodiazepines; Clonidine; Humans; Hypnotics and Sedatives; Infant;

2013
[Pharmacology and upper limb poststroke spasticity: a review. International Society of Prosthetics and Orthotics].
    Annales de readaptation et de medecine physique : revue scientifique de la Societe francaise de reeducation fonctionnelle de readaptation et de medecine physique, 2004, Volume: 47, Issue:8

    Topics: Arm; Baclofen; Botulinum Toxins, Type A; Clonidine; Combined Modality Therapy; Dantrolene; Ergonomic

2004

Trials

1 trial available for clonidine and Neuromuscular Blockade

ArticleYear
[Comparison of clonidine and tramadol added to prilocaine brachial plexus block - analgesia, sensory and motor block].
    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 2005, Volume: 40, Issue:9

    Topics: Adrenergic alpha-Agonists; Adult; Aged; Analgesics, Opioid; Anesthetics, Local; Clonidine; Double-Bl

2005

Other Studies

2 other studies available for clonidine and Neuromuscular Blockade

ArticleYear
Intrathecal propranolol displays long-acting spinal anesthesia with a more sensory-selective action over motor blockade in rats.
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Anesthesia, Spinal; Animals; Area Under Curve; Clonidine; Dose-Response Relationship, Drug; Drug Int

2011
Lack in effects of therapeutic concentrations of dexmedetomidine and clonidine on the neuromuscular blocking action of rocuronium in isolated rat diaphragms.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:5

    Topics: Androstanols; Animals; Clonidine; Dexmedetomidine; Diaphragm; Dose-Response Relationship, Drug; Drug

2007