clonidine has been researched along with Neuralgia, Sciatic in 3 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "PSNL induced bilateral behavioral hyperalgesia, with the ipsilateral level displaying a higher extent of behavior changes than the contralateral side." | 1.37 | Effects of clonidine on bilateral pain behaviors and inflammatory response in rats under the state of neuropathic pain. ( Dong, R; Feng, X; Li, W; Liu, J; Wang, H; Xu, J; Yu, B; Zhang, F, 2011) |
| "In contrast, during hyperalgesia, alpha(2)-adrenergic activation enhances TNFalpha mRNA accumulation." | 1.34 | Antinociception mediated by alpha(2)-adrenergic activation involves increasing tumor necrosis factor alpha (TNFalpha) expression and restoring TNFalpha and alpha(2)-adrenergic inhibition of norepinephrine release. ( Ignatowski, TA; Knight, PR; Spengler, RN; Sud, R, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, F | 1 |
| Feng, X | 1 |
| Dong, R | 1 |
| Wang, H | 1 |
| Liu, J | 1 |
| Li, W | 1 |
| Xu, J | 1 |
| Yu, B | 1 |
| Spengler, RN | 1 |
| Sud, R | 1 |
| Knight, PR | 1 |
| Ignatowski, TA | 1 |
| Mercadante, S | 1 |
| Serretta, R | 1 |
| Sapio, M | 1 |
| Villari, P | 1 |
| Calderone, L | 1 |
3 other studies available for clonidine and Neuralgia, Sciatic
| Article | Year |
|---|---|
Effects of clonidine on bilateral pain behaviors and inflammatory response in rats under the state of neuropathic pain.
Topics: Adrenergic alpha-2 Receptor Antagonists; Analgesics; Analysis of Variance; Animals; Clonidine; Cytok | 2011 |
Antinociception mediated by alpha(2)-adrenergic activation involves increasing tumor necrosis factor alpha (TNFalpha) expression and restoring TNFalpha and alpha(2)-adrenergic inhibition of norepinephrine release.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Brimonidine Tartrate; Clonidine; Dose-Resp | 2007 |
When all else fails: stepwise multiple solutions for a complex cancer pain syndrome.
Topics: Aged; Analgesics; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cholinesterase Inhibitors; Cl | 1999 |