clonidine has been researched along with Nerve Degeneration in 5 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was undertaken to investigate the effects of the alpha2 adrenergic agonist, clonidine, on the near complete cerebral ischemia (NCFI) evoked release of glutamate and aspartate from normo- and hyperglycemic rodent brain tissue using microdialysis tissue techniques." | 7.73 | The effect of clonidine on cell survival, glutamate, and aspartate release in normo- and hyperglycemic rats after near complete forebrain ischemia. ( Jellish, WS; Kindel, G; Murdoch, J; White, FA; Zhang, X, 2005) |
| "The present study was undertaken to investigate the effects of the alpha2 adrenergic agonist, clonidine, on the near complete cerebral ischemia (NCFI) evoked release of glutamate and aspartate from normo- and hyperglycemic rodent brain tissue using microdialysis tissue techniques." | 3.73 | The effect of clonidine on cell survival, glutamate, and aspartate release in normo- and hyperglycemic rats after near complete forebrain ischemia. ( Jellish, WS; Kindel, G; Murdoch, J; White, FA; Zhang, X, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jellish, WS | 1 |
| Murdoch, J | 1 |
| Kindel, G | 1 |
| Zhang, X | 1 |
| White, FA | 1 |
| Yoles, E | 1 |
| Wheeler, LA | 1 |
| Schwartz, M | 1 |
| Chao, HM | 1 |
| Osborne, NN | 1 |
| Reid, JL | 1 |
| Trolin, GG | 1 |
5 other studies available for clonidine and Nerve Degeneration
| Article | Year |
|---|---|
The effect of clonidine on cell survival, glutamate, and aspartate release in normo- and hyperglycemic rats after near complete forebrain ischemia.
Topics: Adrenergic alpha-Agonists; Animals; Aspartic Acid; Blood Glucose; Blood Pressure; Brain Chemistry; B | 2005 |
Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Axons; Brimonid | 1999 |
Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Bridged Bicyclo Compounds; Brimoni | 2001 |
Dopamine supersensitivity in the hypothalamus?
Topics: Animals; Antiparkinson Agents; Body Temperature Regulation; Bromocriptine; Clonidine; Dextroamphetam | 1975 |
Involvement of alpha-adrenergic receptors at different levels of the central nervous system in the regulation of blood pressure and heart frequency.
Topics: Animals; Blood Pressure; Central Nervous System; Clonidine; Dopamine; Heart Rate; Hydroxydopamines; | 1975 |