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clonidine and Multiple System Atrophy Syndrome

clonidine has been researched along with Multiple System Atrophy Syndrome in 14 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"This study was aimed at comparing the diagnostic accuracy of the growth hormone (GH) response to clonidine, arginine and both combined in order to establish a more reliable test to differentiate parkinsonism type multiple system atrophy (MSA-p) from Parkinson's disease (PD)."9.14The comparison of clonidine, arginine and both combined: a growth hormone stimulation test to differentiate multiple system atrophy from idiopathic Parkinson's disease. ( Fu, Y; Song, C; Wan, Q; Zeng, Y; Zhang, K, 2010)
"We assessed the effects of clonidine on blood pressure (BP) and heart rate (HR) in multiple system atrophy (MSA), where the autonomic nervous system lesion site is preganglionic, and in pure autonomic failure (PAF), where it is postganglionic."9.12Hemodynamic effects of clonidine in two contrasting models of autonomic failure: multiple system atrophy and pure autonomic failure. ( Asahina, M; Mathias, CJ; Watson, L; Young, TM, 2006)
"The clonidine-growth hormone test (CGHT) has been proposed as a means of differentiating multiple system atrophy (MSA) from idiopathic Parkinson's disease (PD)."7.71Diagnosing multiple system atrophy with greater accuracy: combined analysis of the clonidine-growth hormone test and external anal sphincter electromyography. ( Kim, BJ; Lee, EA; Lee, WY, 2002)
"Clonidine, a centrally active alpha 2-adrenoreceptor agonist used to lower blood pressure, has been proposed to differentiate central from peripheral autonomic deficits and multiple system atrophy (MSA) from untreated idiopathic Parkinson's disease (IPD)."7.70Is clonidine growth hormone stimulation a good test to differentiate multiple system atrophy from idiopathic Parkinson's disease? ( Echaniz-Laguna, A; Guiraud-Chaumeil, C; Tranchant, C; Warter, JM, 2000)
"This study was aimed at comparing the diagnostic accuracy of the growth hormone (GH) response to clonidine, arginine and both combined in order to establish a more reliable test to differentiate parkinsonism type multiple system atrophy (MSA-p) from Parkinson's disease (PD)."5.14The comparison of clonidine, arginine and both combined: a growth hormone stimulation test to differentiate multiple system atrophy from idiopathic Parkinson's disease. ( Fu, Y; Song, C; Wan, Q; Zeng, Y; Zhang, K, 2010)
"We assessed the effects of clonidine on blood pressure (BP) and heart rate (HR) in multiple system atrophy (MSA), where the autonomic nervous system lesion site is preganglionic, and in pure autonomic failure (PAF), where it is postganglionic."5.12Hemodynamic effects of clonidine in two contrasting models of autonomic failure: multiple system atrophy and pure autonomic failure. ( Asahina, M; Mathias, CJ; Watson, L; Young, TM, 2006)
"The clonidine-growth hormone test (CGHT) has been proposed as a means of differentiating multiple system atrophy (MSA) from idiopathic Parkinson's disease (PD)."3.71Diagnosing multiple system atrophy with greater accuracy: combined analysis of the clonidine-growth hormone test and external anal sphincter electromyography. ( Kim, BJ; Lee, EA; Lee, WY, 2002)
"Clonidine has been proposed to differentiate multiple system atrophy (MSA) from idiopathic Parkinson's disease (IPD), as it does not increase growth hormone (GH) release in MSA."3.71Stimulation of growth hormone release in multiple system atrophy, Parkinson's disease and idiopathic cerebellar ataxia. ( Barone, P; Colao, AM; De Michele, G; Faggiano, A; Filla, A; Pellecchia, MT; Pivonello, R; Salvatore, E, 2001)
"Clonidine, a centrally active alpha 2-adrenoreceptor agonist used to lower blood pressure, has been proposed to differentiate central from peripheral autonomic deficits and multiple system atrophy (MSA) from untreated idiopathic Parkinson's disease (IPD)."3.70Is clonidine growth hormone stimulation a good test to differentiate multiple system atrophy from idiopathic Parkinson's disease? ( Echaniz-Laguna, A; Guiraud-Chaumeil, C; Tranchant, C; Warter, JM, 2000)
"Idiopathic Parkinson's disease (IPD) is a common neurodegenerative disorder whose differential diagnosis from other forms of atypical parkinsonism, for instance multiple system atrophy (MSA) or progressive supranuclear palsy, may be difficult, especially in the early stages."2.43Growth hormone stimulation tests in the differential diagnosis of Parkinson's disease. ( Barone, P; Colao, A; Pellecchia, MT; Pivonello, R, 2006)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.14)18.2507
2000's9 (64.29)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Bonnard, C1
Wirth, T1
Gebus, O1
Fahrer, P1
Montaut, S1
Robelin, L1
Tuzin, N1
Tranchant, C3
Anheim, M2
Alves Do Rego, C1
Namer, IJ1
Marcel, C1
Lefebvre, F1
Lagha-Boukbiza, O1
Renaud, M1
Jordan, J1
Shibao, C1
Biaggioni, I1
Zhang, K1
Zeng, Y1
Song, C1
Fu, Y1
Wan, Q1
Lee, EA1
Kim, BJ1
Lee, WY1
Pellecchia, MT3
Pivonello, R3
Salvatore, E2
Faggiano, A2
Barone, P3
De Michele, G2
Lombardi, G1
Colao, A2
Filla, A2
Young, TM1
Asahina, M1
Watson, L3
Mathias, CJ3
Hiner, BC1
Deguchi, K1
Ikeda, K1
Shimamura, M1
Urai, Y1
Tsukaguchi, M1
Touge, T1
Takeuchi, H1
Sasaki, I1
Kuriyama, S1
Kimber, J2
Guiraud-Chaumeil, C1
Echaniz-Laguna, A1
Warter, JM1
Colao, AM1
Muthane, U1

Reviews

1 review available for clonidine and Multiple System Atrophy Syndrome

ArticleYear
Growth hormone stimulation tests in the differential diagnosis of Parkinson's disease.
    Clinical medicine & research, 2006, Volume: 4, Issue:4

    Topics: Adrenergic alpha-Agonists; Arginine; Clonidine; Diagnosis, Differential; Growth Hormone; Humans; Mul

2006

Trials

2 trials available for clonidine and Multiple System Atrophy Syndrome

ArticleYear
The comparison of clonidine, arginine and both combined: a growth hormone stimulation test to differentiate multiple system atrophy from idiopathic Parkinson's disease.
    Journal of neurology, 2010, Volume: 257, Issue:9

    Topics: Aged; Arginine; Clonidine; Diagnosis, Differential; Drug Combinations; Female; Human Growth Hormone;

2010
Hemodynamic effects of clonidine in two contrasting models of autonomic failure: multiple system atrophy and pure autonomic failure.
    Movement disorders : official journal of the Movement Disorder Society, 2006, Volume: 21, Issue:5

    Topics: Adrenergic alpha-Agonists; Autonomic Nervous System Diseases; Blood Pressure; Case-Control Studies;

2006

Other Studies

11 other studies available for clonidine and Multiple System Atrophy Syndrome

ArticleYear
Clonidine GH stimulation test to differentiate MSA from idiopathic late onset cerebellar ataxia: a prospective, controlled study.
    Journal of neurology, 2020, Volume: 267, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Clonidine; Diagnosis, Differential; Early Diagnosis; Fem

2020
Prospective study of relevance of
    Journal of neurology, 2018, Volume: 265, Issue:9

    Topics: 3-Iodobenzylguanidine; Biomarkers; Clonidine; Diagnosis, Differential; Female; Follow-Up Studies; He

2018
Multiple system atrophy: using clinical pharmacology to reveal pathophysiology.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2015, Volume: 25, Issue:1

    Topics: Atomoxetine Hydrochloride; Autonomic Nervous System; Clonidine; Diagnosis, Differential; Drug Therap

2015
Diagnosing multiple system atrophy with greater accuracy: combined analysis of the clonidine-growth hormone test and external anal sphincter electromyography.
    Movement disorders : official journal of the Movement Disorder Society, 2002, Volume: 17, Issue:6

    Topics: Aged; Anal Canal; Clonidine; Diagnosis, Differential; Electromyography; Female; Human Growth Hormone

2002
Growth hormone response to arginine test distinguishes multiple system atrophy from Parkinson's disease and idiopathic late-onset cerebellar ataxia.
    Clinical endocrinology, 2005, Volume: 62, Issue:4

    Topics: Arginine; Case-Control Studies; Clonidine; Diagnosis, Differential; Female; Growth Hormone; Growth H

2005
Differential diagnosis of Parkinson's disease: a new blood test?
    Clinical medicine & research, 2006, Volume: 4, Issue:4

    Topics: Adrenergic alpha-Agonists; Arginine; Clonidine; Diagnosis, Differential; Growth Hormone; Humans; Mul

2006
Assessment of autonomic dysfunction of multiple system atrophy with laryngeal abductor paralysis as an early manifestation.
    Clinical neurology and neurosurgery, 2007, Volume: 109, Issue:10

    Topics: Aged; Arginine Vasopressin; Cerebellar Ataxia; Clonidine; Diagnosis, Differential; Female; Human Gro

2007
Abnormal suppression of arginine-vasopressin by clonidine in multiple system atrophy.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1999, Volume: 9, Issue:5

    Topics: Adrenergic alpha-Agonists; Aged; Arginine Vasopressin; Blood Pressure; Catecholamines; Clonidine; Di

1999
Is clonidine growth hormone stimulation a good test to differentiate multiple system atrophy from idiopathic Parkinson's disease?
    Journal of neurology, 2000, Volume: 247, Issue:11

    Topics: Aged; Aged, 80 and over; Clonidine; Diagnosis, Differential; Female; Growth Hormone; Humans; Male; M

2000
Stimulation of growth hormone release in multiple system atrophy, Parkinson's disease and idiopathic cerebellar ataxia.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2001, Volume: 22, Issue:1

    Topics: Adrenergic alpha-Agonists; Arginine; Clonidine; Diagnosis, Differential; Drug Administration Schedul

2001
Is clonidine-growth hormone stimulation a good test to differentiate multiple system atrophy from idiopathic Parkinson's disease?
    Journal of neurology, 2002, Volume: 249, Issue:4

    Topics: Clonidine; Diagnosis, Differential; Growth Hormone; Humans; Multiple System Atrophy; Parkinson Disea

2002