Page last updated: 2024-10-25

clonidine and Mental Disorders

clonidine has been researched along with Mental Disorders in 32 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"Clonidine's actions and efficacy in mental disorders are reviewed and examined."5.06Psychiatric indications for clonidine: the neuropharmacologic and clinical basis. ( Bond, WS, 1986)
"People with developmental disabilities are at considerable risk for the development of comorbid psychiatric conditions."2.42Psychopharmacological treatments in persons with dual diagnosis of psychiatric disorders and developmental disabilities. ( Antochi, R; Emery, PC; Stavrakaki, C, 2003)
"Treatment of cocaine addiction includes anti-craving agents, dopamine agonists or blocking agents, antidepressants, and treatment of co-morbid psychiatric disorders, but all with mixed results."2.42Pharmacologic treatments for heroin and cocaine dependence. ( Kleber, HD, 2003)
" Other reported effects are toxic confusional states and psychotic reactions."2.36Psychiatric side effects of antihypertensive drugs other than reserpine. ( Fleminger, R; Paykel, ES; Watson, JP, 1982)
"Treatment with methylphenidate was more effective and better tolerated than treatment with clonidine."1.31[Functioning, comorbidity and treatment of 141 adults with attention deficit hyperactivity disorder (ADHD) at a psychiatric outpatient department]. ( Aeckerlin, LP; Buitelaar, JK; Kooij, JJ, 2001)
"A clonidine treatment had been stopped 129 h earlier."1.27[Withdrawal syndrome during epidural administration of morphine after stopping treatment with clonidine]. ( Oksenhendler, G; Petit, J; Ropiquet, S; Winckler, C, 1984)
"Attempts to do so may only add to confusion and psychotic phenomena."1.27The concept of noise. ( Ratey, JJ; Sands, S, 1986)
"Our findings suggest that patients with endogenous depression are characterized by a subsensitivity of postsynaptic alpha-receptors or of structures related to them."1.26Effect of clonidine on growth hormone release in psychiatric patients and controls. ( Ackenheil, M; Hippius, H; Matussek, N; Müller, F; Schröder, HT; Schultes, H; Wasilewski, B, 1980)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199017 (53.13)18.7374
1990's6 (18.75)18.2507
2000's5 (15.63)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Amos, LB1
Grekowicz, ML1
Kuhn, EM1
Olstad, JD1
Collins, MM1
Norins, NA1
D'Andrea, LA1
Specka, M1
Lopez Gonzales, K1
Scherbaum, N1
Roman, MW1
Moore, SK1
Marsch, LA1
Badger, GJ1
Solhkhah, R1
Hofstein, Y1
Antochi, R1
Stavrakaki, C1
Emery, PC1
Kleber, HD1
Wolraich, ML1
Wibbelsman, CJ1
Brown, TE1
Evans, SW1
Gotlieb, EM1
Knight, JR1
Ross, EC1
Shubiner, HH1
Wender, EH1
Wilens, T1
Ropiquet, S1
Petit, J1
Oksenhendler, G1
Winckler, C1
Garver, DL1
Paykel, ES1
Fleminger, R1
Watson, JP1
Johnson, JM1
Matussek, N1
Ackenheil, M1
Hippius, H1
Müller, F1
Schröder, HT1
Schultes, H1
Wasilewski, B1
Sternberg, DE1
Volkov, VS1
Tsikulin, AE1
Kooij, JJ2
Goekoop, JG1
Gunning, WB1
Gurguis, GN1
Vo, SP1
Blakeley, J1
Orsulak, PJ1
Rush, AJ1
King, VL1
Brooner, RK1
Kidorf, MS1
Stoller, KB1
Mirsky, AF1
Fahlke, C1
Berggren, U1
Balldin, J1
Aeckerlin, LP1
Buitelaar, JK1
Sandifer, MG1
Cohen, DJ1
Riddle, MA1
Leckman, JF1
Sopelana, P1
Bautista, L1
Diéguez, A1
Muga, R1
Tor, J1
Mirmiran, M1
Feenstra, MG1
Dijcks, FA1
Bos, NP1
Van Haaren, F1
Svensson, TH1
Sands, S1
Ratey, JJ1
Adler, LA1
Angrist, B1
Peselow, E1
Reitano, J1
Rotrosen, J1
Siever, LJ1
Uhde, TW1
Insel, TR1
Kaye, WH1
Jimerson, DC1
Lake, CR1
Kafka, M1
Targum, S1
Murphy, DL1
Wålinder, J1
Bond, WS1
Rounsaville, BJ1
Kosten, T1
Kleber, H1

Reviews

11 reviews available for clonidine and Mental Disorders

ArticleYear
New additions to the psychopharmacopia: extended release formulations.
    Issues in mental health nursing, 2011, Volume: 32, Issue:11

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comparative Effectiveness Re

2011
Psychopharmacological treatments in persons with dual diagnosis of psychiatric disorders and developmental disabilities.
    Postgraduate medical journal, 2003, Volume: 79, Issue:929

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Anti-Anxiety Agents; Antidepressive Agents;

2003
Pharmacologic treatments for heroin and cocaine dependence.
    The American journal on addictions, 2003, Volume: 12, Issue:s2

    Topics: Buprenorphine; Clonidine; Cocaine-Related Disorders; Comorbidity; Heroin Dependence; Humans; Mental

2003
Attention-deficit/hyperactivity disorder among adolescents: a review of the diagnosis, treatment, and clinical implications.
    Pediatrics, 2005, Volume: 115, Issue:6

    Topics: Adolescent; Antidepressive Agents; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hypera

2005
Psychiatric side effects of antihypertensive drugs other than reserpine.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:1

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Anxiety; Bethanidine; Clonidine; Debrisoquin;

1982
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
Biologic tests in psychiatry.
    The Psychiatric clinics of North America, 1984, Volume: 7, Issue:3

    Topics: Anxiety Disorders; Apomorphine; Clonidine; Dexamethasone; Dextroamphetamine; Growth Hormone; Humans;

1984
[Attention deficit disorders with hyperactivity in adulthood; implications for diagnosis and treatment].
    Nederlands tijdschrift voor geneeskunde, 1996, Sep-14, Volume: 140, Issue:37

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Attention Deficit Disorder with Hyperactivity; Child;

1996
Pharmacotherapy of Tourette's syndrome and associated disorders.
    The Psychiatric clinics of North America, 1992, Volume: 15, Issue:1

    Topics: Attention Deficit Disorder with Hyperactivity; Clonidine; Female; Haloperidol; Humans; Male; Mental

1992
Functional deprivation of noradrenaline neurotransmission: effects of clonidine on brain development.
    Progress in brain research, 1988, Volume: 73

    Topics: Animals; Brain; Child, Preschool; Clonidine; Fetus; Humans; Mental Disorders; Neurotoxins; Norepinep

1988
Clonidine in abstinence reactions: basic mechanisms.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327

    Topics: Adrenergic alpha-Agonists; Animals; Anxiety Disorders; Autonomic Nervous System; Central Nervous Sys

1986

Trials

4 trials available for clonidine and Mental Disorders

ArticleYear
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
    The Journal of nervous and mental disease, 1984, Volume: 172, Issue:3

    Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic;

1984
Characteristics of norepinephrine and clonidine displacement of [3H]yohimbine binding to platelet alpha2-adrenoreceptors in healthy volunteers.
    Psychiatry research, 1999, Mar-22, Volume: 85, Issue:3

    Topics: Adult; Binding Sites; Blood Platelets; Clonidine; Data Interpretation, Statistical; GTP-Binding Prot

1999
Psychiatric indications for clonidine: the neuropharmacologic and clinical basis.
    Journal of clinical psychopharmacology, 1986, Volume: 6, Issue:2

    Topics: Animals; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug T

1986
Success and failure at outpatient opioid detoxification. Evaluating the process of clonidine- and methadone-assisted withdrawal.
    The Journal of nervous and mental disease, 1985, Volume: 173, Issue:2

    Topics: Adult; Ambulatory Care; Clinical Trials as Topic; Clonidine; Female; Follow-Up Studies; Humans; Male

1985

Other Studies

18 other studies available for clonidine and Mental Disorders

ArticleYear
Treatment of pediatric restless legs syndrome.
    Clinical pediatrics, 2014, Volume: 53, Issue:4

    Topics: Adolescent; Amines; Analgesics; Anticonvulsants; Antioxidants; Benzothiazoles; Child; Child, Prescho

2014
[Outcomes of comprehensive inpatient opiate detoxification in patients re-admitted to treatment within one year].
    Psychiatrische Praxis, 2015, Volume: 42, Issue:1

    Topics: Adult; Aftercare; Clonidine; Comorbidity; Comprehensive Health Care; Female; Germany; Heroin Depende

2015
Improvement in psychopathology among opioid-dependent adolescents during behavioral-pharmacological treatment.
    Journal of addiction medicine, 2011, Volume: 5, Issue:4

    Topics: Adolescent; Affective Symptoms; Ambulatory Care; Behavior Therapy; Buprenorphine; Clonidine; Combine

2011
[Withdrawal syndrome during epidural administration of morphine after stopping treatment with clonidine].
    Annales francaises d'anesthesie et de reanimation, 1984, Volume: 3, Issue:5

    Topics: Aged; Autonomic Nervous System Diseases; Clonidine; Drug Interactions; Epidural Space; Humans; Hyper

1984
A psychobiologic perspective in treating psychiatric disorders.
    Comprehensive therapy, 1984, Volume: 10, Issue:12

    Topics: Anxiety Disorders; Clonidine; Humans; Lithium; Mental Disorders; Mood Disorders; Psychotic Disorders

1984
Effect of clonidine on growth hormone release in psychiatric patients and controls.
    Psychiatry research, 1980, Volume: 2, Issue:1

    Topics: Adult; Alcohol Drinking; Bipolar Disorder; Clonidine; Depressive Disorder; Female; Growth Hormone; H

1980
[Mental changes in hypertensive patients during long-term ambulatory treatment].
    Kardiologiia, 1983, Volume: 23, Issue:8

    Topics: Adult; Ambulatory Care; Antihypertensive Agents; Clonidine; Diuretics; Female; Humans; Hydrochloroth

1983
Neuropsychopharmacology of clonidine-clinical studies.
    Psychopharmacology bulletin, 1981, Volume: 17, Issue:3

    Topics: Clonidine; Emotions; Humans; Mental Disorders; Nervous System; Panic; Psychotropic Drugs; Tourette S

1981
Attention deficit hyperactivity disorder and treatment outcome in opioid abusers entering treatment.
    The Journal of nervous and mental disease, 1999, Volume: 187, Issue:8

    Topics: Adult; Ambulatory Care; Attention; Attention Deficit Disorder with Hyperactivity; Clonidine; Cogniti

1999
Cardiovascular responses to clonidine in alcohol withdrawal: are they related to psychopathology and mental well-being?
    Alcohol (Fayetteville, N.Y.), 2000, Volume: 21, Issue:3

    Topics: Adrenergic alpha-Agonists; Adult; Affect; Alcoholism; Anxiety; Blood Pressure; Central Nervous Syste

2000
[Functioning, comorbidity and treatment of 141 adults with attention deficit hyperactivity disorder (ADHD) at a psychiatric outpatient department].
    Nederlands tijdschrift voor geneeskunde, 2001, Aug-04, Volume: 145, Issue:31

    Topics: Adrenergic alpha-Agonists; Adult; Age Factors; Attention Deficit Disorder with Hyperactivity; Centra

2001
The hypertensive psychiatric patient: pharmacologic problems.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:9

    Topics: Antihypertensive Agents; Clonidine; Depression; Diuretics; Drug Interactions; Guanethidine; Humans;

1978
[Factors affecting the course of hospital detoxication of drug addicts].
    Medicina clinica, 1991, Sep-21, Volume: 97, Issue:9

    Topics: Adult; Cannabis; Clonidine; Cocaine; Evaluation Studies as Topic; Female; Guanfacine; Heroin Depende

1991
[Drug addiction and detoxication units].
    Medicina clinica, 1991, Sep-21, Volume: 97, Issue:9

    Topics: Adult; Ambulatory Care; Clonidine; Female; Guanfacine; Heroin Dependence; Hospital Units; Humans; Ma

1991
The concept of noise.
    Psychiatry, 1986, Volume: 49, Issue:4

    Topics: Adrenergic beta-Antagonists; Clonidine; Cognition; Confusion; Humans; Mental Disorders; Personality

1986
Clonidine in neuroleptic-induced akathisia.
    The American journal of psychiatry, 1987, Volume: 144, Issue:2

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Anxiety; Clonidine; Hospitalization; Humans; M

1987
Biological alterations in the primary affective disorders and other tricyclic-responsive disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:1

    Topics: Adult; Agoraphobia; Anorexia Nervosa; Clonidine; Cyclic AMP; Depressive Disorder; Dihydroergotoxine;

1985
The use of clonidine in psychiatric disorders. Preliminary clinical observations.
    Acta psychiatrica Scandinavica. Supplementum, 1986, Volume: 327

    Topics: Anxiety Disorders; Bipolar Disorder; Clonidine; Humans; Mental Disorders; Panic; Psychophysiologic D

1986