clonidine has been researched along with Lesion of Sciatic Nerve in 8 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine's effects were prevented by co-administration of an alpha2-adrenoceptor antagonist." | 1.34 | Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis. ( Eisenach, JC; Romero-Sandoval, A, 2007) |
| "Clonidine's effects were blocked by the alpha2-adrenoceptor antagonist, BRL44408." | 1.33 | Perineural clonidine reduces p38 mitogen-activated protein kinase activation in sensory neurons. ( Eisenach, JC; Liu, B, 2006) |
| "Tizanidine was effective in reducing sensitivity to heat, as measured by paw withdrawal latency, and did not cause sedation at smaller doses." | 1.31 | Systemic tizanidine hydrochloride (Zanaflex) relieves thermal hyperalgesia in rats with an experimental mononeuropathy. ( Azevedo, MI; Chalfoun, AG; Denson, DD; Hord, AH, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (87.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhu, JX | 1 |
| Xu, FY | 1 |
| Xu, WJ | 1 |
| Zhao, Y | 1 |
| Qu, CL | 1 |
| Tang, JS | 1 |
| Barry, DM | 1 |
| Du, JQ | 1 |
| Huo, FQ | 1 |
| Malyshkin, AA | 1 |
| Medvedev, IO | 1 |
| Danysz, W | 1 |
| Bespalov, AY | 1 |
| Liu, B | 2 |
| Eisenach, JC | 5 |
| Romero-Sandoval, A | 3 |
| Bynum, T | 1 |
| Hord, AH | 1 |
| Chalfoun, AG | 1 |
| Denson, DD | 1 |
| Azevedo, MI | 1 |
8 other studies available for clonidine and Lesion of Sciatic Nerve
| Article | Year |
|---|---|
The role of α₂ adrenoceptor in mediating noradrenaline action in the ventrolateral orbital cortex on allodynia following spared nerve injury.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Bicuculline; | 2013 |
Anti-allodynic interactions between NMDA receptor channel blockers and morphine or clonidine in neuropathic rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Analgesics, Opioid; Animals; Clonidine; Cyclopenta | 2005 |
Hyperexcitability of axotomized and neighboring unaxotomized sensory neurons is reduced days after perineural clonidine at the site of injury.
Topics: Action Potentials; Animals; Axotomy; Clonidine; Ganglia, Spinal; Hyperalgesia; Male; Membrane Potent | 2005 |
Perineural clonidine reduces mechanical hypersensitivity and cytokine production in established nerve injury.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Clonidine; Cytok | 2006 |
Perineural clonidine reduces p38 mitogen-activated protein kinase activation in sensory neurons.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Cell Count; Clon | 2006 |
Clonidine reduces hypersensitivity and alters the balance of pro- and anti-inflammatory leukocytes after local injection at the site of inflammatory neuritis.
Topics: Adrenergic alpha-Agonists; Analgesics; Analysis of Variance; Anesthesia, Local; Animals; Apoptosis; | 2007 |
Analgesia induced by perineural clonidine is enhanced in persistent neuritis.
Topics: Analgesics; Animals; Behavior, Animal; Calcium-Binding Proteins; Clonidine; Dose-Response Relationsh | 2007 |
Systemic tizanidine hydrochloride (Zanaflex) relieves thermal hyperalgesia in rats with an experimental mononeuropathy.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Disease Models, Animal; Hot Temperature; Hyperalgesia | 2001 |