clonidine has been researched along with Labor Pain in 8 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Labor Pain: Pain associated with OBSTETRIC LABOR in CHILDBIRTH. It is caused primarily by UTERINE CONTRACTION as well as pressure on the CERVIX; BLADDER; and the GASTROINTESTINAL TRACT. Labor pain mostly occurs in the ABDOMEN; the GROIN; and the BACK.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the quality of analgesia with epidural neostigmine and clonidine, added to initial spinal analgesia, and to test the hypothesis that the incidence of breakthrough pain could be reduced and patient satisfaction improved." | 5.19 | Epidural neostigmine and clonidine improves the quality of combined spinal epidural analgesia in labour: a randomised, double-blind controlled trial. ( Boogmans, T; Devroe, S; Roofthooft, E; Valkenborgh, T; Van de Velde, M; Vertommen, J, 2014) |
| "The addition of clonidine to epidural levobupivacaine and sufentanil for patient-controlled epidural analgesia in labour improved analgesia, reduced the supplementation rate and reduced pruritus without improvement in maternal satisfaction." | 5.14 | Effects of a continuous low-dose clonidine epidural regimen on pain, satisfaction and adverse events during labour: a randomized, double-blind, placebo-controlled trial. ( Aubrun, F; Bouret, C; Broisin, F; Charpiat, B; Clement, HJ; Derre, E; Huissoud, C; Lopez, F; Pignal, C; Schoeffler, M; Viale, JP; Wallet, F, 2010) |
| "Epidural administration of neostigmine and clonidine, following the spinal injection of local anesthetic, has a stronger analgesic effect in managing labor pain and reduces hourly anesthetic consumption." | 4.91 | Effects of epidural neostigmine and clonidine in labor analgesia: a systematic review and meta-analysis. ( Xu, MJ; Zhang, N, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boogmans, T | 1 |
| Vertommen, J | 1 |
| Valkenborgh, T | 1 |
| Devroe, S | 1 |
| Roofthooft, E | 1 |
| Van de Velde, M | 1 |
| Zhang, N | 1 |
| Xu, MJ | 1 |
| Kuczkowski, KM | 4 |
| Chandra, S | 3 |
| Wallet, F | 1 |
| Clement, HJ | 1 |
| Bouret, C | 1 |
| Lopez, F | 1 |
| Broisin, F | 1 |
| Pignal, C | 1 |
| Schoeffler, M | 1 |
| Derre, E | 1 |
| Charpiat, B | 1 |
| Huissoud, C | 1 |
| Aubrun, F | 1 |
| Viale, JP | 1 |
| Roelants, F | 1 |
| Lavand'homme, PM | 1 |
| Mercier-Fuzier, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Double Blind Clinical Trial Comparing Programed Intermittent Epidural Boluses (PIEB) Versus Patient Controlled Epidural Analgesia (PCEA) With Epidural or Combined Spinal-epidural (CSE) Technique[NCT02768272] | Phase 4 | 240 participants (Actual) | Interventional | 2016-03-01 | Completed | ||
| Epidural Analgesia During Labour. Impact of Clonidine Addition to Levobupivacaine and Sufentanil[NCT00437996] | Phase 3 | 85 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for clonidine and Labor Pain
| Article | Year |
|---|---|
Effects of epidural neostigmine and clonidine in labor analgesia: a systematic review and meta-analysis.
Topics: Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthetics, Local; Apgar Score; Clonidine; Delivery, | 2015 |
4 trials available for clonidine and Labor Pain
| Article | Year |
|---|---|
Epidural neostigmine and clonidine improves the quality of combined spinal epidural analgesia in labour: a randomised, double-blind controlled trial.
Topics: Adult; Amides; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Anesthesi | 2014 |
Effects of a continuous low-dose clonidine epidural regimen on pain, satisfaction and adverse events during labour: a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analgesia, Epidural; Analgesia, Patient-Controlled; An | 2010 |
Epidural administration of neostigmine and clonidine to induce labor analgesia: evaluation of efficacy and local anesthetic-sparing effect.
Topics: Anesthesia, Epidural; Anesthetics, Local; Clonidine; Drug Therapy, Combination; Female; Humans; Labo | 2005 |
Management of labor pain with single dose spinal analgesia: Indonesian perspective.
Topics: Adult; Analgesics; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Clonidin | 2007 |
3 other studies available for clonidine and Labor Pain
| Article | Year |
|---|---|
Intrathecal clonidine for control of labor pain: international perspective.
Topics: Analgesics; Anesthesia, Obstetrical; Clonidine; Dose-Response Relationship, Drug; Female; Humans; In | 2008 |
Subarachnoid clonidine for labor pain: the two sides of the coin.
Topics: Analgesia, Obstetrical; Analgesics; Anesthesia, Obstetrical; Anesthesia, Spinal; Cesarean Section; C | 2012 |
Maternal satisfaction with single-dose spinal analgesia for labor pain in Indonesia: a landmark study.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics; Anesthesia, Spinal; Benchmarking; Bupivacaine | 2008 |