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clonidine and Ischemia

clonidine has been researched along with Ischemia in 11 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Clonidine treatment resulted in less outer medullary microvascular damage (demonstrated by colloidal carbon staining), higher outer medullary blood flow 1 to 2 hours after unclamping, fewer casts, and higher creatinine clearance and free water clearance/creatinine clearance 4 to 6 hours after unclamping compared with controls."5.26Clonidine after renal ischemia to lessen acute renal failure and microvascular damage. ( Hamilton, B; Ideura, T; Saito, H; Silvia, CB; Solez, K, 1980)
" An antiallodynic topical combination of apraclonidine + lisofylline was also found to effectively relieve depressed postocclusive reactive hyperemia in CPIP rats (N = 61) and to increase formazan production in postischemic tissues (skin and muscle) (N = 56)."3.80Topical combinations to treat microvascular dysfunction of chronic postischemia pain. ( Abaji, R; Coderre, TJ; Laferrière, A; Ragavendran, JV; Tsai, CY, 2014)
"morphine and baclofen were superior to clonidine and R-PIA."1.31Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats. ( Hao, JX; Sollevi, A; von Heijne, M; Xu, XJ, 2001)
"clonidine was reversed by the selective alpha 2-adrenoceptor antagonist atipamezole."1.29Effects of intrathecal vs. systemic clonidine in treating chronic allodynia-like response in spinally injured rats. ( Hao, JX; Wiesenfeld-Hallin, Z; Xu, XJ; Yu, W, 1996)
"Clonidine treatment resulted in fewer, shorter, and thinner hyaline casts."1.26The effect of clonidine on tubular obstruction in postischemic acute renal failure in the rabbit demonstrated by microradiography and microdissection. ( Heptinstall, RH; Ideura, T; Solez, K, 1980)
"Clonidine treatment resulted in less outer medullary microvascular damage (demonstrated by colloidal carbon staining), higher outer medullary blood flow 1 to 2 hours after unclamping, fewer casts, and higher creatinine clearance and free water clearance/creatinine clearance 4 to 6 hours after unclamping compared with controls."1.26Clonidine after renal ischemia to lessen acute renal failure and microvascular damage. ( Hamilton, B; Ideura, T; Saito, H; Silvia, CB; Solez, K, 1980)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's3 (27.27)18.2507
2000's4 (36.36)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Laferrière, A1
Abaji, R1
Tsai, CY1
Ragavendran, JV1
Coderre, TJ1
Uysal, H1
Larsson, LE1
Efendi, H1
Burke, D1
Ertekin, C1
Ideura, T2
Solez, K2
Heptinstall, RH1
Silvia, CB1
Hamilton, B1
Saito, H1
El Tamer, A1
Prokopenko, I1
Wülfert, E1
Hanin, I1
Hao, JX2
Yu, W1
Xu, XJ2
Wiesenfeld-Hallin, Z1
Lévecque, JP1
Ladagnous, JF1
Saïssy, JM1
O'Connor, KJ1
Grady, JF1
Moore, CJ1
Licandro, J1
Brenner, LA1
von Heijne, M1
Sollevi, A1
Grey, MJ1
Ladouceur, M1
Andersen, JB1
Nielsen, JB1
Sinkjaer, T1
Teodoresco, P1
Câmpeanu, A1

Other Studies

11 other studies available for clonidine and Ischemia

ArticleYear
Topical combinations to treat microvascular dysfunction of chronic postischemia pain.
    Anesthesia and analgesia, 2014, Volume: 118, Issue:4

    Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Animals; Capillaries; Chemistry, Phar

2014
Medium-latency reflex response of soleus elicited by peroneal nerve stimulation.
    Experimental brain research, 2009, Volume: 193, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Cold Temperature; Electric Stimulation; Elec

2009
The effect of clonidine on tubular obstruction in postischemic acute renal failure in the rabbit demonstrated by microradiography and microdissection.
    The American journal of pathology, 1980, Volume: 98, Issue:1

    Topics: Acute Kidney Injury; Animals; Clonidine; Creatinine; Female; Ischemia; Kidney; Kidney Tubules; Micro

1980
Clonidine after renal ischemia to lessen acute renal failure and microvascular damage.
    Kidney international, 1980, Volume: 18, Issue:3

    Topics: Acute Kidney Injury; Animals; Clonidine; Creatinine; Disease Models, Animal; Diuresis; Female; Ische

1980
Mivazerol, a novel alpha2-agonist and potential anti-ischemic drug, inhibits KC1-stimulated neurotransmitter release in rat nervous tissue preparations.
    Journal of neurochemistry, 1996, Volume: 67, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Aspartic Acid; Brain Stem; Clonidine; Glutamates; Hippocampus; I

1996
Effects of intrathecal vs. systemic clonidine in treating chronic allodynia-like response in spinally injured rats.
    Brain research, 1996, Oct-14, Volume: 736, Issue:1-2

    Topics: Animals; Blood Pressure; Clonidine; Female; Injections, Intraperitoneal; Injections, Spinal; Ischemi

1996
[Analgesia by continuous tibial nerve block after ischemia and amputation].
    Annales francaises d'anesthesie et de reanimation, 1997, Volume: 16, Issue:8

    Topics: Aged; Amputation, Surgical; Analgesia; Bupivacaine; Clonidine; Humans; Ischemia; Leg; Male; Nerve Bl

1997
Use of a clonidine patch in the treatment of ischemic ulcerations of the foot.
    Journal of the American Podiatric Medical Association, 2000, Volume: 90, Issue:6

    Topics: Administration, Cutaneous; Adrenergic alpha-Agonists; Clonidine; Foot Diseases; Foot Ulcer; Humans;

2000
Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats.
    European journal of pain (London, England), 2001, Volume: 5, Issue:1

    Topics: Adenosine; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Cloni

2001
Group II muscle afferents probably contribute to the medium latency soleus stretch reflex during walking in humans.
    The Journal of physiology, 2001, Aug-01, Volume: 534, Issue:Pt 3

    Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Local; Ankle; Clonidine; Cold Temperature; Electromyo

2001
[Effects of clonidine treatment in advanced forms of essential arterial hypertension].
    Revue roumaine de medecine interne (1964), 1973, Volume: 10, Issue:6

    Topics: Aged; Aortic Arch Syndromes; Bradycardia; Cerebral Hemorrhage; Chemical Phenomena; Chemistry; Chlort

1973