clonidine has been researched along with Ischemia in 11 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine treatment resulted in less outer medullary microvascular damage (demonstrated by colloidal carbon staining), higher outer medullary blood flow 1 to 2 hours after unclamping, fewer casts, and higher creatinine clearance and free water clearance/creatinine clearance 4 to 6 hours after unclamping compared with controls." | 5.26 | Clonidine after renal ischemia to lessen acute renal failure and microvascular damage. ( Hamilton, B; Ideura, T; Saito, H; Silvia, CB; Solez, K, 1980) |
| " An antiallodynic topical combination of apraclonidine + lisofylline was also found to effectively relieve depressed postocclusive reactive hyperemia in CPIP rats (N = 61) and to increase formazan production in postischemic tissues (skin and muscle) (N = 56)." | 3.80 | Topical combinations to treat microvascular dysfunction of chronic postischemia pain. ( Abaji, R; Coderre, TJ; Laferrière, A; Ragavendran, JV; Tsai, CY, 2014) |
| "morphine and baclofen were superior to clonidine and R-PIA." | 1.31 | Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats. ( Hao, JX; Sollevi, A; von Heijne, M; Xu, XJ, 2001) |
| "clonidine was reversed by the selective alpha 2-adrenoceptor antagonist atipamezole." | 1.29 | Effects of intrathecal vs. systemic clonidine in treating chronic allodynia-like response in spinally injured rats. ( Hao, JX; Wiesenfeld-Hallin, Z; Xu, XJ; Yu, W, 1996) |
| "Clonidine treatment resulted in fewer, shorter, and thinner hyaline casts." | 1.26 | The effect of clonidine on tubular obstruction in postischemic acute renal failure in the rabbit demonstrated by microradiography and microdissection. ( Heptinstall, RH; Ideura, T; Solez, K, 1980) |
| "Clonidine treatment resulted in less outer medullary microvascular damage (demonstrated by colloidal carbon staining), higher outer medullary blood flow 1 to 2 hours after unclamping, fewer casts, and higher creatinine clearance and free water clearance/creatinine clearance 4 to 6 hours after unclamping compared with controls." | 1.26 | Clonidine after renal ischemia to lessen acute renal failure and microvascular damage. ( Hamilton, B; Ideura, T; Saito, H; Silvia, CB; Solez, K, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laferrière, A | 1 |
| Abaji, R | 1 |
| Tsai, CY | 1 |
| Ragavendran, JV | 1 |
| Coderre, TJ | 1 |
| Uysal, H | 1 |
| Larsson, LE | 1 |
| Efendi, H | 1 |
| Burke, D | 1 |
| Ertekin, C | 1 |
| Ideura, T | 2 |
| Solez, K | 2 |
| Heptinstall, RH | 1 |
| Silvia, CB | 1 |
| Hamilton, B | 1 |
| Saito, H | 1 |
| El Tamer, A | 1 |
| Prokopenko, I | 1 |
| Wülfert, E | 1 |
| Hanin, I | 1 |
| Hao, JX | 2 |
| Yu, W | 1 |
| Xu, XJ | 2 |
| Wiesenfeld-Hallin, Z | 1 |
| Lévecque, JP | 1 |
| Ladagnous, JF | 1 |
| Saïssy, JM | 1 |
| O'Connor, KJ | 1 |
| Grady, JF | 1 |
| Moore, CJ | 1 |
| Licandro, J | 1 |
| Brenner, LA | 1 |
| von Heijne, M | 1 |
| Sollevi, A | 1 |
| Grey, MJ | 1 |
| Ladouceur, M | 1 |
| Andersen, JB | 1 |
| Nielsen, JB | 1 |
| Sinkjaer, T | 1 |
| Teodoresco, P | 1 |
| Câmpeanu, A | 1 |
11 other studies available for clonidine and Ischemia
| Article | Year |
|---|---|
Topical combinations to treat microvascular dysfunction of chronic postischemia pain.
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Animals; Capillaries; Chemistry, Phar | 2014 |
Medium-latency reflex response of soleus elicited by peroneal nerve stimulation.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Clonidine; Cold Temperature; Electric Stimulation; Elec | 2009 |
The effect of clonidine on tubular obstruction in postischemic acute renal failure in the rabbit demonstrated by microradiography and microdissection.
Topics: Acute Kidney Injury; Animals; Clonidine; Creatinine; Female; Ischemia; Kidney; Kidney Tubules; Micro | 1980 |
Clonidine after renal ischemia to lessen acute renal failure and microvascular damage.
Topics: Acute Kidney Injury; Animals; Clonidine; Creatinine; Disease Models, Animal; Diuresis; Female; Ische | 1980 |
Mivazerol, a novel alpha2-agonist and potential anti-ischemic drug, inhibits KC1-stimulated neurotransmitter release in rat nervous tissue preparations.
Topics: Adrenergic alpha-Agonists; Animals; Aspartic Acid; Brain Stem; Clonidine; Glutamates; Hippocampus; I | 1996 |
Effects of intrathecal vs. systemic clonidine in treating chronic allodynia-like response in spinally injured rats.
Topics: Animals; Blood Pressure; Clonidine; Female; Injections, Intraperitoneal; Injections, Spinal; Ischemi | 1996 |
[Analgesia by continuous tibial nerve block after ischemia and amputation].
Topics: Aged; Amputation, Surgical; Analgesia; Bupivacaine; Clonidine; Humans; Ischemia; Leg; Male; Nerve Bl | 1997 |
Use of a clonidine patch in the treatment of ischemic ulcerations of the foot.
Topics: Administration, Cutaneous; Adrenergic alpha-Agonists; Clonidine; Foot Diseases; Foot Ulcer; Humans; | 2000 |
Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats.
Topics: Adenosine; Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Cloni | 2001 |
Group II muscle afferents probably contribute to the medium latency soleus stretch reflex during walking in humans.
Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Local; Ankle; Clonidine; Cold Temperature; Electromyo | 2001 |
[Effects of clonidine treatment in advanced forms of essential arterial hypertension].
Topics: Aged; Aortic Arch Syndromes; Bradycardia; Cerebral Hemorrhage; Chemical Phenomena; Chemistry; Chlort | 1973 |