clonidine has been researched along with Infarction, Middle Cerebral Artery in 2 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to investigate the protective effects of the alpha-2 adrenergic receptor (α2-AR) agonist, clonidine, on the cerebral ischemia-reperfusion (I/R) injury and elaborate the underlying mechanisms." | 8.12 | Clonidine ameliorates cerebral ischemia-reperfusion injury by up-regulating the GluN3 subunits of NMDA receptor. ( Chen, J; Chen, Y; He, Z; Li, ZC; Yang, DD; Zhang, J; Zhao, B, 2022) |
| "This study aimed to investigate the protective effects of the alpha-2 adrenergic receptor (α2-AR) agonist, clonidine, on the cerebral ischemia-reperfusion (I/R) injury and elaborate the underlying mechanisms." | 4.12 | Clonidine ameliorates cerebral ischemia-reperfusion injury by up-regulating the GluN3 subunits of NMDA receptor. ( Chen, J; Chen, Y; He, Z; Li, ZC; Yang, DD; Zhang, J; Zhao, B, 2022) |
| "Clonidine and yohimbine were intraperitoneally given to the rats each day for a week before ischemia." | 1.43 | Clonidine preconditioning alleviated focal cerebral ischemic insult in rats via up-regulating p-NMDAR1 and down-regulating NMDAR2A / p-NMDAR2B. ( Bo, Z; Lingling, Y; Min, Z; Xizhou, Z; Yan, W; Yanli, L; Yunhong, Z; Zhangao, C; Zhi, H; Zicheng, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, J | 1 |
| Zhang, J | 1 |
| Yang, DD | 1 |
| Li, ZC | 1 |
| Zhao, B | 1 |
| Chen, Y | 1 |
| He, Z | 1 |
| Yanli, L | 1 |
| Xizhou, Z | 1 |
| Yan, W | 1 |
| Bo, Z | 1 |
| Yunhong, Z | 1 |
| Zicheng, L | 1 |
| Lingling, Y | 2 |
| Zhangao, C | 1 |
| Min, Z | 1 |
| Zhi, H | 1 |
2 other studies available for clonidine and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Clonidine ameliorates cerebral ischemia-reperfusion injury by up-regulating the GluN3 subunits of NMDA receptor.
Topics: Animals; Brain Ischemia; Clonidine; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents | 2022 |
Clonidine preconditioning alleviated focal cerebral ischemic insult in rats via up-regulating p-NMDAR1 and down-regulating NMDAR2A / p-NMDAR2B.
Topics: Animals; Brain Edema; Clonidine; Down-Regulation; Infarction, Middle Cerebral Artery; Ischemic Preco | 2016 |