clonidine has been researched along with Hypothermia, Accidental in 38 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a rare case of Shapiro's syndrome variantrevealed by episodes of headache with spontaneous hypothermia witheffectiveness of clonidine therapy in a 76-year-old Parkinson's disease woman." | 8.02 | Episodic headache with spontaneous hypothermia reveal Shapiro's syndrome variant with effectiveness of clonidine therapy. ( Andriuta, D; Aubignat, M; Krystkowiak, P; Tir, M, 2021) |
| "As alpha-2 agonists preserve ventilator drive, patients presenting with acute respiratory distress syndrome (ARDS, Pa02/FiO2 < 200) were managed using sedation with an alpha-2 agonist, clonidine, combined to spontaneous ventilation (SV) + pressure support ventilation (PS)." | 7.78 | Combination of clonidine sedation and spontaneous breathing-pressure support upon acute respiratory distress syndrome: a feasibility study in four patients. ( de Guys, J; Galliez, M; Ghignone, M; Guerry, M; Lahmar, M; Lalot, JM; Monarchi, R; Pichot, C; Picoche, A; Quintin, L; Rousseau, R; Saboya-Steinbach, MI; Thomas, D, 2012) |
| "Clonidine administered to mice induced hypothermia and this effect was antagonized by a single dose of the following beta-agonists: salbutamol, isoprenaline and terbutaline." | 7.66 | Influence of salbutamol and other beta-agonists on hypothermia induced by clonidine, apomorphine and reserpine in mice. ( Mogilnicka, E; Müller, M, 1981) |
| "Clonidine therapy was also associated with a return to normal central temperature regulation." | 5.28 | Clonidine therapy for Shapiro's syndrome. ( Anderson, JA; Edwards, CR; Walker, BR, 1992) |
| "The goals of this two-part study were to determine the dose of clonidine to prevent postoperative shivering after mild hypothermia and to evaluate the effect of clonidine on recovery from anesthesia in patients undergoing surgery for intracranial lesions." | 5.11 | Intraoperative clonidine administration to neurosurgical patients. ( Brown, R; Lobo, EP; Stapelfeldt, C; Talke, PO, 2005) |
| " Clonidine produced a linear, dose-dependent impairment of PEEP-induced hypothermia protection: final core temperatures were 35." | 5.11 | Clonidine produces a dose-dependent impairment of baroreflex-mediated thermoregulatory responses to positive end-expiratory pressure in anaesthetized humans. ( Mizobe, T; Nakajima, Y; Sessler, DI; Sunaguchi, M; Ueno, H, 2005) |
| "We report a rare case of Shapiro's syndrome variantrevealed by episodes of headache with spontaneous hypothermia witheffectiveness of clonidine therapy in a 76-year-old Parkinson's disease woman." | 4.02 | Episodic headache with spontaneous hypothermia reveal Shapiro's syndrome variant with effectiveness of clonidine therapy. ( Andriuta, D; Aubignat, M; Krystkowiak, P; Tir, M, 2021) |
| "In the newborn rat, morphine causes profound respiratory depression and hypothermia while clonidine causes minimal respiratory depression and stabilizes CBT." | 3.80 | Breathing and temperature control disrupted by morphine and stabilized by clonidine in neonatal rats. ( Bierman, A; Ezell, T; Gauda, EB; Kesavan, K; Northington, FJ; Nunes, AR; Tankersley, CG, 2014) |
| "As alpha-2 agonists preserve ventilator drive, patients presenting with acute respiratory distress syndrome (ARDS, Pa02/FiO2 < 200) were managed using sedation with an alpha-2 agonist, clonidine, combined to spontaneous ventilation (SV) + pressure support ventilation (PS)." | 3.78 | Combination of clonidine sedation and spontaneous breathing-pressure support upon acute respiratory distress syndrome: a feasibility study in four patients. ( de Guys, J; Galliez, M; Ghignone, M; Guerry, M; Lahmar, M; Lalot, JM; Monarchi, R; Pichot, C; Picoche, A; Quintin, L; Rousseau, R; Saboya-Steinbach, MI; Thomas, D, 2012) |
| ") antagonized the hypothermia induced by the D2/D1 receptor agonist, apomorphine (16 mg/kg, s." | 3.70 | Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms. ( Baker, GB; Bourin, M; Colombel, MC; Redrobe, JP, 1998) |
| " Injection of the adrenergic agonists, CGP-12177 and clonidine (beta, and alpha adrenergic agonists, respectively) abrogated the hypothermia induced by HU-210." | 3.69 | Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat. Relation to the adrenergic system and endogenous pyrogens. ( Mechoulam, R; Ovadia, H; Weidenfeld, J; Wohlman, A, 1995) |
| " (+)-OXA and (-)-OXA attenuated reserpine- and apomorphine-induced hypothermia [(+)-OXA in a more potent manner] in mice and reduced the immobility time in the behavioural despair test in rats." | 3.68 | Some central pharmacological effects of (+)- and (-)-oxaprotiline. ( Maj, J; Rogóź, Z; Skuza, G; Sowińska, H, 1990) |
| " The alpha 1-noradrenergic receptor agonist, phenylephrine, but not methoxamine, applied to the AH/POA produced a dose-dependent hypothermia of up to 2." | 3.67 | Hypothermia: role of alpha 1- and alpha 2-noradrenergic receptors in the hypothalamus of the cat. ( Beleslin, DB; Myers, RD; Rezvani, AH, 1987) |
| "Clonidine and several other structurally related imidazolidines were administered intraperitoneally to mice and their capacity to cause hypothermia was used as an indication of their ability to enter the central nervous system." | 3.66 | The hypothermic effect of clonidine and other imidazolidines in relation to their ability to enter the central nervous system in mice. ( McLennan, PL, 1981) |
| "Clonidine administered to mice induced hypothermia and this effect was antagonized by a single dose of the following beta-agonists: salbutamol, isoprenaline and terbutaline." | 3.66 | Influence of salbutamol and other beta-agonists on hypothermia induced by clonidine, apomorphine and reserpine in mice. ( Mogilnicka, E; Müller, M, 1981) |
| "The presence of agenesis of corpus callosum is not a strict criteria of the syndrome; the most important presenting symptom is paroxysmal hypothermia." | 1.43 | [A rare case of thermoregulation disorder: Shapiro syndrome]. ( Szabó, J; Varga, ET; Vécsei, L; Zádori, D, 2016) |
| "We performed a prospective case series to seek dosage or clinical parameters to better identify patients who need direct medical evaluation." | 1.33 | Toxic clonidine ingestion in children. ( Anderson, DL; Colvin, JM; Johnson, PB; Klein-Schwartz, W; Spiller, HA; Villalobos, D, 2005) |
| "Clonidine therapy was also associated with a return to normal central temperature regulation." | 1.28 | Clonidine therapy for Shapiro's syndrome. ( Anderson, JA; Edwards, CR; Walker, BR, 1992) |
| "3." | 1.28 | Chronic treatment with amitriptyline produces subsensitivity to the hypothermic effects of clonidine. ( Davidson, R; Dilsaver, SC; Majchrzak, M, 1989) |
| "Clonidine therapy was associated with an initial dramatic decrease in the frequency of diaphoretic episodes as well as with a fall in NE release rate and increases in NE clearance and volume of distribution." | 1.28 | Altered norepinephrine metabolism in Shapiro's syndrome. ( Cahalan, DD; Forrester, JM; Halter, JB; Linares, OA; Rosen, SG; Sanfield, JA, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (39.47) | 18.7374 |
| 1990's | 10 (26.32) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 5 (13.16) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Elkoundi, A | 1 |
| Mounir, K | 1 |
| Atmani, W | 1 |
| Balkhi, H | 1 |
| Aubignat, M | 1 |
| Tir, M | 1 |
| Krystkowiak, P | 1 |
| Andriuta, D | 1 |
| Mathur, S | 2 |
| Mathur, A | 1 |
| Dubey, T | 1 |
| Jain, S | 1 |
| Agarwal, H | 1 |
| Kulshrestha, M | 1 |
| Jangid, R | 1 |
| Ram, C | 1 |
| Kesavan, K | 1 |
| Ezell, T | 1 |
| Bierman, A | 1 |
| Nunes, AR | 1 |
| Northington, FJ | 1 |
| Tankersley, CG | 1 |
| Gauda, EB | 1 |
| Lewis, SR | 1 |
| Nicholson, A | 1 |
| Smith, AF | 1 |
| Alderson, P | 1 |
| Szabó, J | 1 |
| Zádori, D | 1 |
| Varga, ET | 1 |
| Vécsei, L | 1 |
| Pichot, C | 1 |
| Picoche, A | 1 |
| Saboya-Steinbach, MI | 1 |
| Rousseau, R | 1 |
| de Guys, J | 1 |
| Lahmar, M | 1 |
| Thomas, D | 1 |
| Guerry, M | 1 |
| Lalot, JM | 1 |
| Monarchi, R | 1 |
| Galliez, M | 1 |
| Ghignone, M | 1 |
| Quintin, L | 1 |
| Chintawar, SD | 1 |
| Somani, RS | 1 |
| Kasture, VS | 1 |
| Kasture, SB | 1 |
| Quail, MT | 1 |
| Shannon, M | 1 |
| Stapelfeldt, C | 1 |
| Lobo, EP | 1 |
| Brown, R | 1 |
| Talke, PO | 1 |
| Spiller, HA | 1 |
| Klein-Schwartz, W | 1 |
| Colvin, JM | 1 |
| Villalobos, D | 1 |
| Johnson, PB | 1 |
| Anderson, DL | 1 |
| Mizobe, T | 1 |
| Nakajima, Y | 1 |
| Sunaguchi, M | 1 |
| Ueno, H | 1 |
| Sessler, DI | 1 |
| Tambasco, N | 1 |
| Corea, F | 1 |
| Bocola, V | 1 |
| Buvat, J | 1 |
| Buvat-Herbaut, M | 1 |
| McLennan, PL | 1 |
| Marruecos, L | 1 |
| Roglan, A | 1 |
| Frati, ME | 1 |
| Artigas, A | 1 |
| Mullin, MJ | 1 |
| Ferko, AP | 1 |
| Lin, MT | 1 |
| Chandra, A | 1 |
| Ko, WC | 1 |
| Chen, YM | 1 |
| Müller, M | 1 |
| Mogilnicka, E | 1 |
| Ovadia, H | 1 |
| Wohlman, A | 1 |
| Mechoulam, R | 1 |
| Weidenfeld, J | 1 |
| Rosa, G | 1 |
| Pinto, G | 1 |
| Orsi, P | 1 |
| de Blasi, RA | 1 |
| Conti, G | 1 |
| Sanitá, R | 1 |
| La Rosa, I | 1 |
| Gasparetto, A | 1 |
| Salmi, P | 1 |
| Karlsson, T | 1 |
| Ahlenius, S | 1 |
| Bernard, JM | 1 |
| Fulgencio, JP | 1 |
| Delaunay, L | 1 |
| Bonnet, F | 1 |
| Redrobe, JP | 1 |
| Bourin, M | 1 |
| Colombel, MC | 1 |
| Baker, GB | 1 |
| Okechukwu, CN | 1 |
| Pesanti, E | 1 |
| Conner, CS | 1 |
| Watanabe, AS | 1 |
| Pai, GS | 1 |
| Lipsitz, DJ | 1 |
| Walker, BR | 1 |
| Anderson, JA | 1 |
| Edwards, CR | 1 |
| Feller, DJ | 1 |
| Crabbe, JC | 1 |
| Niida, H | 1 |
| Takeuchi, K | 1 |
| Ueshima, K | 1 |
| Okabe, S | 1 |
| Maj, J | 1 |
| Rogóź, Z | 1 |
| Skuza, G | 1 |
| Sowińska, H | 1 |
| Dilsaver, SC | 1 |
| Davidson, R | 1 |
| Majchrzak, M | 1 |
| Kulinskiĭ, VI | 1 |
| Gertsov, GE | 1 |
| Plotnikov, NIu | 1 |
| Bezachev, VG | 1 |
| Beleslin, DB | 2 |
| Rezvani, AH | 2 |
| Myers, RD | 2 |
| Sanfield, JA | 1 |
| Linares, OA | 1 |
| Cahalan, DD | 1 |
| Forrester, JM | 1 |
| Halter, JB | 1 |
| Rosen, SG | 1 |
| Yehuda, S | 1 |
| Wurtman, RJ | 1 |
| Waldeck, B | 1 |
3 reviews available for clonidine and Hypothermia, Accidental
| Article | Year |
|---|---|
Alpha-2 adrenergic agonists for the prevention of shivering following general anaesthesia.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, General; Clonidine; Dexmedetomidine; Humans; Hypotherm | 2015 |
[New data on the physiology and treatment of vasomotor menopausal flushing].
Topics: Animals; Climacteric; Clonidine; Estrogens; Female; Haplorhini; Humans; Hypothalamic Hormones; Hypot | 1983 |
Clonidine overdose: a review.
Topics: Adolescent; Adult; Cardiovascular Diseases; Child, Preschool; Clonidine; Coma; Female; Humans; Hypot | 1979 |
4 trials available for clonidine and Hypothermia, Accidental
| Article | Year |
|---|---|
Intraoperative clonidine administration to neurosurgical patients.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Anesthesia Recovery Period; Clonidine; Double-Blind Method; | 2005 |
Clonidine produces a dose-dependent impairment of baroreflex-mediated thermoregulatory responses to positive end-expiratory pressure in anaesthetized humans.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, General; Angiotensin II; Baroreflex; Body Temperature | 2005 |
Control of post anaesthetic shivering with nefopam hydrochloride in mildly hypothermic patients after neurosurgery.
Topics: Adult; Anesthesia Recovery Period; Anesthesia, Intravenous; Basal Metabolism; Blood Pressure; Body T | 1995 |
Clonidine does not impair redistribution hypothermia after the induction of anesthesia.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, General; Blood Pressure; Body Temperature; Body Temper | 1998 |
31 other studies available for clonidine and Hypothermia, Accidental
| Article | Year |
|---|---|
Management of a patient with Shapiro syndrome variant during pregnancy.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Agenesis of Corpus Callosum; Clonidine; Diagnosis, Diff | 2020 |
Episodic headache with spontaneous hypothermia reveal Shapiro's syndrome variant with effectiveness of clonidine therapy.
Topics: Aged; Agenesis of Corpus Callosum; Clonidine; Female; Headache; Humans; Hyperhidrosis; Hypothermia; | 2021 |
Shapiro syndrome.
Topics: Adult; Agenesis of Corpus Callosum; Anti-Arrhythmia Agents; Clonidine; Humans; Hyperhidrosis; Hypoth | 2013 |
Breathing and temperature control disrupted by morphine and stabilized by clonidine in neonatal rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Animals, Newborn; Body Temperature; Carbon Dioxide; C | 2014 |
[A rare case of thermoregulation disorder: Shapiro syndrome].
Topics: Agenesis of Corpus Callosum; Body Temperature Regulation; Clonidine; Corpus Callosum; Humans; Hungar | 2016 |
Combination of clonidine sedation and spontaneous breathing-pressure support upon acute respiratory distress syndrome: a feasibility study in four patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Antipsychotic Agents; Clonidine; Cons | 2012 |
Nootropic activity of Albizzia lebbeck in mice.
Topics: Albizzia; Animals; Avoidance Learning; Behavior, Animal; Brain Chemistry; Catalepsy; Clonidine; Depr | 2002 |
Severe hypothermia caused by clonidine.
Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Female; Humans; Hypothermia; Severity of Illness Index | 2003 |
Toxic clonidine ingestion in children.
Topics: Analgesics; Bradycardia; Child; Child, Preschool; Clonidine; Coma; Dose-Response Relationship, Drug; | 2005 |
Subtotal corpus callosum agenesis with recurrent hyperhidrosis-hypothermia (Shapiro syndrome).
Topics: Abdominal Pain; Adrenergic alpha-Agonists; Adult; Agenesis of Corpus Callosum; Autonomic Nervous Sys | 2005 |
The hypothermic effect of clonidine and other imidazolidines in relation to their ability to enter the central nervous system in mice.
Topics: Animals; Blood-Brain Barrier; Body Temperature; Brain; Clonidine; Dose-Response Relationship, Drug; | 1981 |
Clonidine overdose.
Topics: Bradycardia; Brain; Clonidine; Female; Humans; Hypotension; Hypothermia; Middle Aged | 1983 |
Ethanol and functional tolerance: interactions with pimozide and clonidine.
Topics: Animals; Body Temperature; Clonidine; Drug Interactions; Drug Tolerance; Ethanol; Hypothermia; Male; | 1981 |
Serotonergic mechanisms of clonidine-induced hypothermia in rats.
Topics: 5,7-Dihydroxytryptamine; Animals; Body Temperature Regulation; Brain; Catecholamines; Clonidine; Hyd | 1981 |
Influence of salbutamol and other beta-agonists on hypothermia induced by clonidine, apomorphine and reserpine in mice.
Topics: Albuterol; Animals; Apomorphine; Clonidine; Drug Interactions; Hypothermia; Isoproterenol; Male; Mic | 1981 |
Characterization of the hypothermic effect of the synthetic cannabinoid HU-210 in the rat. Relation to the adrenergic system and endogenous pyrogens.
Topics: Animals; Cannabinoids; Clonidine; Dinoprostone; Dose-Response Relationship, Drug; Dronabinol; Humans | 1995 |
Antagonism by SCH 23390 of clozapine-induced hypothermia in the rat.
Topics: Amphetamines; Animals; Benzazepines; Body Temperature; Body Temperature Regulation; Chromans; Clonid | 1994 |
Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Antidepressive Agents; Apomorphine; Brain; | 1998 |
Episodic spontaneous hyperhidrosis hypothermia in human immunodeficiency virus-positive patients.
Topics: AIDS Dementia Complex; Clonidine; HIV Seropositivity; Humans; Hyperhidrosis; Hypothermia; Male; Midd | 1999 |
Clonidine poisoning.
Topics: Atropine; Blood Pressure; Bradycardia; Child, Preschool; Clonidine; Coma; Heart Rate; Humans; Hypoth | 1976 |
Clonidine therapy for Shapiro's syndrome.
Topics: Adult; Agenesis of Corpus Callosum; Body Temperature Regulation; Clonidine; Humans; Hyperhidrosis; H | 1992 |
Effect of neurotransmitter-selective drugs in mice selected for differential sensitivity to the hypothermic actions of ethanol.
Topics: Animals; Body Temperature; Chlorpromazine; Clonidine; Dopamine Agents; Drug Interactions; Ethanol; F | 1991 |
Vagally mediated acid hypersecretion and lesion formation in anesthetized rat under hypothermic conditions.
Topics: Animals; Atropine; Carbachol; Clonidine; Ganglionic Blockers; Gastric Acid; Gastric Mucosa; Gastroin | 1991 |
Some central pharmacological effects of (+)- and (-)-oxaprotiline.
Topics: Animals; Anthracenes; Apomorphine; Behavior, Animal; Clonidine; Dopamine; Hypothermia; Male; Maproti | 1990 |
Chronic treatment with amitriptyline produces subsensitivity to the hypothermic effects of clonidine.
Topics: Amitriptyline; Animals; Body Temperature; Clonidine; Drug Administration Schedule; Drug Synergism; H | 1989 |
[Changes in the sensitivity of the alpha 2- and beta 1-adrenoreactive systems during the intensive cooling of rats acclimatized to cold].
Topics: Acclimatization; Animals; Clonidine; Cold Temperature; Female; Heart Rate; Hypothermia; Isoprotereno | 1988 |
Rostral hypothalamus: a new neuroanatomical site of neurochemically-induced emesis in the cat.
Topics: Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Female; Hypothalamus; Hypothermia; Norepinep | 1987 |
Altered norepinephrine metabolism in Shapiro's syndrome.
Topics: Aged; Agenesis of Corpus Callosum; Clonidine; Female; Humans; Hypothermia; Middle Aged; Norepinephri | 1989 |
Hypothermia: role of alpha 1- and alpha 2-noradrenergic receptors in the hypothalamus of the cat.
Topics: Animals; Body Temperature; Cats; Clonidine; Female; Hypothermia; Kinetics; Methoxamine; Norepinephri | 1987 |
Release of brain dopamine as the probable mechanism for the hypothermic effect of D-amphetamine.
Topics: Animals; Apomorphine; Brain Chemistry; Clonidine; Dextroamphetamine; Dihydroxyphenylalanine; Dopamin | 1972 |
Sensitization by caffeine of central catecholamine receptors.
Topics: Animals; Body Temperature; Caffeine; Clonidine; Dopamine; Dose-Response Relationship, Drug; Drug Syn | 1973 |