clonidine has been researched along with Hypertension in 1375 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Hypertension: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine has clearly been shown to be effective in the treatment of all grades of hypertension." | 10.14 | Clonidine in the treatment of hypertension. ( Garrett, BN; Kaplan, NM, 1980) |
| "This single-centre, prospective trial investigated the use of CST in 60 patients with suspected PPGL associated with out-patient elevations of plasma normetanephrine (NMN) and/or metanephrine (MN), in most cases accompanied with hypertension or an adrenal mass." | 9.51 | Clonidine suppression test for a reliable diagnosis of pheochromocytoma: When to use. ( Dralle, H; Führer, D; Geroula, A; Pamporaki, C; Schmid, KW; Tsiomidou, S; Unger, N; Van Baal, L; Weber, F, 2022) |
| "There are limited and nonconcordant data on the rapidity and safety of blood pressure response to clonidine in the setting of asymptomatic severe hypertension." | 9.22 | Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension. ( Ghazi, L; Hanna, J; Peixoto, AJ; Shah, T; Simonov, M; Wilson, FP; Yamamoto, Y, 2022) |
| "Of the 50 patients with hypertension (American Society of Anesthesiologists class II), 25 received 2 mL of 2% lidocaine with clonidine (15 μg/mL) and 25 received lidocaine with epinephrine (12." | 9.16 | Is clonidine an adequate alternative to epinephrine as a vasoconstrictor in patients with hypertension? ( Patil, PM; Patil, SP, 2012) |
| "To clarify the effects of bedtime administration of the centrally acting alpha(2)-agonists, guanabenz and clonidine, on morning hypertension." | 9.10 | Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurements. ( Aoki, Y; Araki, T; Chonan, K; Hashimoto, J; Hozawa, A; Imai, Y; Kikuya, M; Matsubara, M; Michimata, M; Nishimura, T; Ohkubo, T; Ugajin, T; Yamaguchi, J, 2003) |
| "Using a randomized double-blind placebo-controlled design, 20 patients with essential hypertension (systolic pressure >160 mm Hg or diastolic pressure >95 mm Hg for > or =1 yr) were assigned to receive clonidine (or placebo), 6 microg/kg orally 120 min before anesthesia and 3 microg/kg intravenously over 60 min before the end of surgery." | 9.09 | Cardiac baroreflex during the postoperative period in patients with hypertension: effect of clonidine. ( Annat, G; Bégou, G; Bonnet, F; Cottet-Emard, JM; Ghignone, M; Hughson, R; Levron, JC; Parlow, JL; Quintin, L; Sagnard, P; Viale, JP, 1999) |
| "Clonidine reduces postoperative circulatory instability in patients with essential hypertension." | 9.09 | The effects of clonidine on sensitivity to phenylephrine and nitroprusside in patients with essential hypertension recovering from surgery. ( Begou, G; Parlow, JL; Quintin, L; Sagnard, P; Viale, JP, 1999) |
| "The objective of this study was to assess the efficacy and tolerability of transdermal clonidine in inner-city African-American and Hispanic-American patients with essential hypertension." | 9.09 | Clinical experience with transdermal clonidine in African-American and Hispanic-American patients with hypertension: evaluation from a 12-week prospective, open-label clinical trial in community-based clinics. ( Dias, VC; Oparil, S; Reilly, PA; Snarr, P; Tendler, B; White, WB, 1999) |
| "This report describes the effects of indapamide versus transdermal clonidine on left ventricular hypertrophy (LVH) in hypertensive diabetic patients." | 9.08 | Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients. ( Berk, LS; Tan, LG; Tan, SA, 1996) |
| "A double-blind, double-dummy, parallel-group trial that used a predominantly Hispanic patient population with mild-to-moderate hypertension was designed to compare the efficacy, safety, and acceptability of monotherapy with either transdermal clonidine applied once a week or terazosin tablets taken once a day." | 9.08 | Alpha 2-agonist versus alpha 1-antagonist in mild-to-moderate hypertension: comparison of transdermal clonidine and terazosin monotherapies. ( Alvarez, C; Harris, SI, 1997) |
| "A rapid increase in isoflurane concentration can induce tachycardia and hypertension and increase plasma catecholamine concentrations." | 9.07 | Clonidine and lidocaine inhibition of isoflurane-induced tachycardia in humans. ( Namba, H; Namiki, A; Tanaka, S; Tsuchida, H, 1994) |
| "The efficacy and safety of two different galenic formulations of transdermal clonidine systems were compared in 905 patients with mild to moderate essential hypertension during a 12 weeks observation period." | 9.07 | Efficacy and safety of two different galenic formulations of a transdermal clonidine system in the treatment of hypertension. ( Göbel, BO; Kolloch, RE; Mehlburger, L; Schumacher, H, 1993) |
| "The clonidine patch offers for the first time the unique possibility of a once-a-week transdermal therapy of hypertension due to direct absorption of clonidine through the skin." | 9.07 | One year efficacy and tolerability of clonidine administered by the transdermal route in patients with mild to moderate essential hypertension--a multicentre open label study. The Antihypertensive Patch Italian Study (APIS) Investigators. ( , 1993) |
| "The long-term safety and efficacy of transdermal clonidine (C-TTS) was evaluated in 102 patients with mild to moderate hypertension over a mean treatment period of 4." | 9.07 | Long-term (5 year) experience with transdermal clonidine in the treatment of mild to moderate hypertension. ( Breidthardt, J; Mehlburger, L; Schumacher, H, 1993) |
| "This study was designed to compare the clinical efficacy and safety of oral clonidine and oral labetalol in the treatment of severe hypertension in an emergency department setting." | 9.07 | Oral labetalol versus oral clonidine in the emergency treatment of severe hypertension. ( Atkin, SH; Beaty, P; Cuffie, C; Jaker, MA; Quadrel, MA; Soto-Greene, ML, 1992) |
| "The central alpha-2-adrenergic receptor agonist, clonidine (300 micrograms daily) significantly increased the plasma beta-endorphin-like immunoreactivity (beta ELI) in 12 patients with mild to moderate essential hypertension in a randomized, crossover study." | 9.07 | Adrenergic and dopaminergic regulation of circulating beta-endorphin-like immunoreactivity in hypertension. ( Alföldi, A; Farsang, C; Fekete, MI; Simkó, K, 1991) |
| "In 10 patients with moderate essential hypertension, the neurohumoral and hemodynamic effects of 4 days' treatment with 2 x 75 micrograms clonidine (C), 2 x 20 mg nifedipine retard (N), and a combination of the two (C/N) were studied and compared with baseline values." | 9.07 | [Nifedipine-clonidine combination in essential hypertension. Hemodynamic and neurohumoral findings of the combination in comparison with the effect of the individual substances]. ( Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V, 1991) |
| "This double-blind, double-dummy, randomized clinical trial, conducted in elderly patients with mild hypertension, compared adherence to treatment, efficacy, side effects, and quality of life during treatment with transdermal clonidine versus oral sustained-release verapamil (verapamil-SR)." | 9.07 | Therapeutic adherence in the elderly: transdermal clonidine compared to oral verapamil for hypertension. ( Burris, JF; Cook, ME; Papademetriou, V; Wallin, JD; Weidler, DJ, 1991) |
| "The study objective was to determine the effects of monotherapy with clonidine and atenolol versus placebo on serum lipids, apolipoproteins, and blood pressure in patients with mild primary hypertension." | 9.06 | The effects of clonidine hydrochloride versus atenolol monotherapy on serum lipids, lipid subfractions, and apolipoproteins in mild hypertension. ( Bradley, CA; Burger, C; Hays, JT; Houston, MC; Nadeau, J; Olafsson, L; Swift, L, 1990) |
| "To evaluate the role of the sympathetic nervous system in essential hypertension and the influence of clonidine, 28 male subjects with mild to moderate hypertension were either treated with low-dose clonidine (n = 14, mean age: 42." | 9.06 | Hemodynamic and neurohumoral effects of low-dose clonidine in mild to moderate hypertension. ( Rüddel, H; Schmieder, R; Schulte, W; von Eiff, AW, 1987) |
| "We compared the effects of transdermal clonidine and oral atenolol on acute exercise performance and on conditioning response to an 8-week program of regular aerobic exercise in young, otherwise healthy subjects with mild hypertension." | 9.06 | Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension. ( Davidman, M; Davies, SF; Graif, JL; Husebye, DG; Iber, C; Maddy, MM; McArthur, CD; O'Connell, MB; Path, MJ, 1989) |
| " To investigate the contribution of sedation to the cardiovascular effects induced by clonidine, we studied patients with essential hypertension on two separate occasions when similar levels of sedation were induced by clonidine and nitrazepam." | 9.06 | The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension. ( Kooner, JS; Mathias, CJ; Peart, WS, 1989) |
| "The role of alpha 2-adrenoceptor stimulation by clonidine on the secretion of beta-endorphin, ACTH, and cortisol in essential hypertension and obesity was studied in 45 subjects: 15 non-obese hypertensives, 10 obese hypertensives, 11 obese normotensives, and 9 healthy subjects." | 9.06 | Effect of clonidine on beta-endorphin, ACTH and cortisol secretion in essential hypertension and obesity. ( Jeske, W; Puciłowska, J; Soszynski, P; Słowinska-Srzednicka, J; Wierzbicki, M; Zgliczynski, S, 1988) |
| "Fifty-one patients with urgent hypertension were treated in the emergency department with either oral nifedipine or oral clonidine in a randomized double-blind prospective study." | 9.06 | Oral nifedipine vs oral clonidine in the treatment of urgent hypertension. ( Atkin, S; Brosch, F; Jaker, M; Schmid, G; Soto, M, 1989) |
| "We evaluated the safety and efficacy of transdermal clonidine (TC) in 23 patients with essential hypertension over a two-year period." | 9.06 | Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension. ( Horning, JR; McNulty, R; Simmons, JL; Williams, L; Zawada, ET, 1988) |
| "In a six-week multicenter, double-blind comparison study, moxonidine and clonidine HCl were tested in 122 and 30 outpatients, respectively, with mild to moderate hypertension (World Health Organization stage I and II; highest measured diastolic blood pressure, 90 to 115 mm Hg)." | 9.06 | Comparison of moxonidine and clonidine HCl in treating patients with hypertension. ( Plänitz, V, 1987) |
| "Guanfacine, an alpha 2-adrenoceptor agonist, was compared with clonidine as step-2 therapy of mild to moderate essential hypertension in a 24-week, double-blind, randomized, parallel evaluation to determine efficacy, safety and occurrence of withdrawal syndrome." | 9.06 | Comparison of guanfacine versus clonidine for efficacy, safety and occurrence of withdrawal syndrome in step-2 treatment of mild to moderate essential hypertension. ( Bedsole, G; Fillingim, J; Hall, D; Haring, O; Jagger, P; Lewin, A; McMahon, FG; Roginsky, M; Stepansky, W; Wilson, MF, 1986) |
| "In 30 patients with mild essential hypertension, clonidine hydrochloride was delivered from a skin patch reservoir designed to release medication at a constant rate for seven days." | 9.06 | Transdermal clonidine in mild hypertension. A randomized, double-blind, placebo-controlled trial. ( Daugirdas, JT; Hano, JE; Hockenberry, B; Ing, TS; Neubauer, JA; Popli, S, 1986) |
| "The effect of naloxone on the hypotensive and bradycardiac action of clonidine was studied in 27 hospitalized patients with uncomplicated mild-to-moderate essential hypertension." | 9.05 | Possible involvement of an endogenous opioid in the antihypertensive effect of clonidine in patients with essential hypertension. ( Farsang, C; Juhasz, I; Kapocsi, J; Kunos, G, 1982) |
| " In the present study the effect of the opiate receptor blocker naloxone on the reduction of blood pressure and plasma noradrenaline induced by the alpha 2-agonist clonidine was investigated in nine patients with essential hypertension." | 9.05 | Failure of naloxone to reduce the clonidine induced reduction of blood pressure and plasma noradrenaline in patients with essential hypertension. ( Bramnert, M; Hökfelt, B, 1983) |
| "24 mg/day) and propranolol (average 105 mg/day) on home blood pressure readings in 16 patients with borderline hypertension was investigated in a randomized, double-blind, placebo crossover design." | 9.05 | Use of clonidine and propranolol as monotherapy in borderline hypertension. ( Cottier, C; Julius, S, 1983) |
| "We measured the first dosage effect and the long-term effect of lofexidine on blood pressure, heart rate, plasma catecholamines, and their major metabolites in 16 patients with primary hypertension who were receiving 50 mg hydrochlorothiazide twice a day while they were recumbent and upright and during isometric handgrip contraction." | 9.05 | Hemodynamic effect of lofexidine with a diuretic in hypertension. ( Alexander, N; Maronde, RF; Velasquez, M; Vlachakis, ND, 1983) |
| "5 mg of slow-release (sr) clonidine, 800 mg of acebutolol, and of both drugs combined on blood pressure and the water-salt balance were compared in 10 patients with essential hypertension." | 9.05 | Clonidine, acebutolol and their interaction in essential hypertension: effects on blood pressure and the control of water and electrolyte balance. ( Cornette, M; Degoulet, P; Fermé, I; Ménard, J; Plouin, PF, 1983) |
| "The antihypertensive drug, clonidine, was administered to 18 patients, 8 females and 10 males, with WHO grade I-II essential hypertension in two forms, either as sustained-release depot capsule of 250 micrograms once daily or as standard clonidine preparation, 150 micrograms twice daily." | 9.05 | Comparison of sustained-release and standard preparations of clonidine in essential hypertension. ( Fyhrquist, F, 1983) |
| "The acute and chronic effects of fixed dosages of clonidine and prazosin on supine and upright blood pressure, the renin-angiotensin-aldosterone system, and plasma catecholamines were compared in 24 patients with essential hypertension." | 9.05 | Comparative antihypertensive and endocrinologic effects of clonidine and prazosin in patients with essential hypertension. ( Drayer, JI; Hubbell, FA; Rose, DE; Weber, MA, 1984) |
| "3 mg clonidine and 3 mg guanfacine were equiactive in decreasing blood pressure and heart rate in 17 subjects with essential hypertension." | 9.05 | Effects of clonidine and guanfacine in essential hypertension. ( Alföldi, S; Farsang, C; Kapocsi, J; Vajda, L; Varga, K, 1984) |
| "A double-blind crossover trial was undertaken to compare the efficacy of sustained-release clonidine and long-acting propranolol in the treatment of 20 patients (8 males and 12 females) with sustained hypertension." | 9.05 | Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension. ( Lawson, AA; Rodrigues, E, 1982) |
| "Nine patients with hypertension were given xipamide 40 mg orally as monotherapy on alternate days." | 9.05 | Clinical trial of xipamide in the treatment of hypertension. ( Antonelli, S; Lentini, S; Leone, G; Paoletti, V, 1980) |
| "The antihypertensive and side effects of guanfacine and clonidine were compared in 24 patients with essential hypertension in a single-blind crossover study." | 9.05 | Evaluation of guanfacine and clonidine in essential hypertension: a single-blind crossover study. ( Louis, WJ; Miach, PJ, 1980) |
| "The efficacy, safety, and tolerability of lofexidine, a centrally acting imidazoline derivative, were compared to that of clonidine in a randomized double-blind trial in 28 patients with moderate essential hypertension." | 9.05 | Lofexidine and clonidine in moderate essential hypertension. ( Dustan, HP; Oparil, S; Smith, LR; Wilkins, LH; Winternitz, SR, 1981) |
| "A prospective, double-blind, randomized controlled trial was carried out, comparing alpha-methyldopa and clonidine hydrochloride in 100 pregnant women with hypertension." | 9.05 | Clonidine hydrochloride--a safe and effective antihypertensive agent in pregnancy. ( Child, A; Henderson-Smart, DJ; Horvath, JS; Korda, A; Phippard, A; Tiller, DJ, 1985) |
| "Fifty-nine patients with primary hypertension, WHO stages I and II, participated in a 6-month multicentre, single-blind study to evaluate the effects of small doses of clonidine (75-300 micrograms daily) on blood pressure (BP) and serum lipoproteins." | 9.05 | Clonidine in mild to moderate hypertension: effects on blood pressure and serum lipoproteins. ( Karlberg, BE; Lins, LE; Rössner, S, 1985) |
| "1 A double-blind cross over trial between clonidine, propranolol and a placebo in patients with moderate hypertension has been performed." | 9.04 | A comparative trial of clonidine, propranolol and placebo in the treatment of moderate hypertension. ( Raftery, EB; Wilkinson, PR, 1977) |
| " Propranolol was given to eight haemodialysed patients with resistant arterial hypertension for periods ranging from 6 to 16 months." | 9.04 | Long-term propranolol treatment of resistant arterial hypertension in haemodialysed patients. ( Biagini, M; Maggiore, Q; Misefari, M; Zoccali, C, 1975) |
| "To assess the hemodynamic effects of Clonidine in hypertensive patients (pts) with an acute myocardial infarction (AMI), we administered the drug to 12 such patients either in a single bolus (75--150 micrograms in 5 min - 8 pts) or by continuous infusion (0." | 8.76 | [Hemodynamic effects of intravenous clonidine in patients with acute myocardial infarction]. ( Foresti, A; Lotto, A; Massari, FM; Moglia, F, 1982) |
| " Sitagliptin and clonidine are effective curing drugs for controlling diabetes and hypertension, while insulin and norepinephrine are the biomarkers of these two diseases." | 8.12 | Chiral Luminescent Sensor Eu-BTB@d-Carnitine Applied in the Highly Effective Ratiometric Sensing of Curing Drugs and Biomarkers for Diabetes and Hypertension. ( Ding, B; Huo, J; Jiang, YP; Liu, YY; Shi, YF; Sun, PP; Wang, K; Wang, XR; Wang, XZ; Zhang, ZQ; Zhu, NJ, 2022) |
| "The agonists of alpha(2)-adrenergic receptors such as clonidine, rilmenidine or monoxidine are known to lower blood pressure (BP) through a reduction of brain sympathetic outflow but their chronic antihypertensive effects in rats with low-renin or high-renin forms of experimental hypertension were not studied yet." | 8.12 | Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension. ( Behuliak, M; Řezáčová, L; Vaněčková, I; Zicha, J, 2022) |
| "Oral clonidine is used to treat hypertension but often produces sedation and severe dry mouth; intrathecal clonidine is used to treat chronic pain but may produce hypotension." | 7.81 | Intrathecal Clonidine via Lumbar Puncture Decreases Blood Pressure in Patients With Poorly Controlled Hypertension. ( D'Angelo, R; Hildebrand, KR; Hong, KS; Komanski, CB; North, JM; Rauck, RL, 2015) |
| "The objective of this study was to determine the pharmacokinetic parameters of clonidine during pregnancy compared with previously published data in nonpregnant subjects." | 7.75 | Clonidine pharmacokinetics in pregnancy. ( Buchanan, ML; Carr, DB; Easterling, TR; Hebert, MF; Mattison, DR; Nelson, WL; Risler, LJ; Shen, DD, 2009) |
| "A 68-year-old woman developed eosinophilic pleural effusion and systemic eosinophilia 2 months after starting antihypertensive therapy with diltiazem." | 7.74 | Diltiazem-induced eosinophilic pleural effusion. ( Akritidis, N; Katsanou, A; Koutsouka, F; Pappas, G; Petrakis, D; Raptis, L, 2007) |
| "Clonidine prevented the L-NNA induced hypertension dose-dependently, but did not effect the heart rates decreased by L-NNA." | 7.74 | [Clonidine prevents development of hypertension in N (omega)-nitro-L-arginine-treated rats]. ( Aksulu, HE; Ilhan, S; Oktar, S, 2008) |
| "Clonidine-induced delirium has rarely been reported." | 7.73 | Clonidine-induced delirium. ( Delaney, J; Doddamani, S; Ostfeld, R; Spevack, D, 2006) |
| "Abrupt withdrawal from clonidine therapy is a well-known cause of hyperadrenergic symptoms, but reports of acute myocardial infarction are extremely rare." | 7.72 | Acute myocardial infarction as a complication of clonidine withdrawal. ( Gifford, W; Goldberg, R; Kishineff, S; Simic, J, 2003) |
| "To report a case of possible clonidine-induced hypertension (by Naranjo score) in a patient with a C4 spinal lesion." | 7.71 | Clonidine-induced hypertension in a patient with a spinal lesion. ( Backo, AL; Clause, SL; Gibbs, KA; Triller, DM, 2002) |
| "The role that the central sympathetic nervous system plays in the development of obesity hypertension and insulin was evaluated by feeding dogs a high fat diet with or without clonidine treatment." | 7.70 | Clonidine prevents insulin resistance and hypertension in obese dogs. ( Babu, K; Mao, HZ; Marker, P; Rocchini, AJ; Rocchini, AP, 1999) |
| "Clonidine, an alpha2 agonist, was administered through a nasogastric tube for the treatment of hypertension in a head-injury patient with elevated plasma catecholamines." | 7.70 | Oral clonidine to control hypertension after head injury. ( Asada, A; Kariya, N; Nishi, S; Shindoh, M; Yukioka, H, 1999) |
| " The authors present a 10-year-old boy chronically treated with lisinopril, an angiotensin converting enzyme inhibitor, to control hypertension who developed hypotension following the addition of tizanidine, an alpha-2 agonist, for the treatment of spasticity." | 7.70 | Hypotension following the initiation of tizanidine in a patient treated with an angiotensin converting enzyme inhibitor for chronic hypertension. ( Johnson, TR; Tobias, JD, 2000) |
| "Clonidine is an alpha-adrenergic agent that is used in the treatment of hypertension." | 7.69 | Clonidine-induced bradycardia. ( Blount, BW; Golusinski, LL, 1995) |
| "In this paper we describe a typical case of tetanus and report our observations with the centrally acting alpha 2-adrenoreceptor agonist clonidine." | 7.69 | Autonomic disturbance in severe tetanus: failure of parenteral clonidine to control blood pressure. ( Brown, JL; Mathias, CJ; Sinding, H, 1994) |
| "In order to investigate the changes of endogenous opiate systems in hypertension and their possible role in the pathogenesis in hypertension, we measured plasma concentrations of beta-endorphin, leucine-enkephalin, neurotension, arginine vasopressin, plasma renin activity and angiotensin II by radioimmunoassay in 60 normal persons and 120 patients with essential hypertension." | 7.69 | Plasma levels of beta-endorphin, leucine enkephalin and arginine vasopressin in patients with essential hypertension and the effects of clonidine. ( Ding, H; Wang, C; Zhang, T; Zheng, X, 1995) |
| "Plasma concentrations of beta-endorphin (beta-EP), leucine enkephalin (LEK), arginine vasopressin (AVP), neurotensin (NT), renin activity (PRA) and angiotensin II (AT-II) were determined before and after the treatment with clonidine in 117 patients with essential hypertension." | 7.68 | [Changes in plasma neuropeptides before and after clonidine in patients with essential hypertension]. ( Zheng, X, 1993) |
| "In the present study, we evaluated the relationship between hypertension and the antinociceptive effect of clonidine in genetically hypertensive rats." | 7.68 | Dissociation of hypertension and enhanced clonidine-induced antinociception in spontaneously hypertensive rats. ( Lee, HK; Lin, JC; Tsao, WL; Wang, Y, 1993) |
| "In the present study it was investigated whether hypertension induced by dopamine or hypotension induced by clonidine could influence the relative blood distribution in a s." | 7.68 | Effects of clonidine-induced hypotension and dopamine-induced hypertension on blood flows in prostatic adenocarcinoma (Dunning R3327) and normal tissues. ( Damber, JE; Grankvist, K; Henriksson, R; Jonsson, O; Widmark, A, 1992) |
| "To determine whether alterations of left ventricular (LV) structure are associated with improved LV function under chronic clonidine monotherapy (300-450 g/day) of essential hypertension, 11 male patients (age range 47-61 years) were followed for 5." | 7.68 | Left ventricular muscle mass and diastolic function in patients with essential hypertension under long-term clonidine monotherapy. ( Bahavar, H; Hüting, J; Mitrovic, V; Schlepper, M; Thormann, J, 1991) |
| "We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor." | 7.68 | Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991) |
| "Authors assessed correlation between venous blood catecholamines and prostaglandins concentrations before and after inhibition of sympathetic activity by clonidine in patients with primary hypertension or pheochromocytoma." | 7.68 | [Correlations between catecholamines and prostaglandins in patients with primary arterial hypertension and pheochromocytoma in basic conditions and after administration of clonidine]. ( Bar-Andziak, E; Chojnowski, K; Feltynowski, T; Ignatowska-Switalska, H; Lazecki, D; Wocial, B, 1990) |
| "The decrease in arterial blood pressure in patients with essential arterial hypertension treated with clonidine is associated, in 88." | 7.68 | Effect of clonidine on serum inorganic phosphorus in patients with essential arterial hypertension. ( Uza, G, 1990) |
| " They investigated therefore in 15 patients with essential hypertension (EH) and in three patients with pheochromocytoma the urinary excretion of free noradrenaline (NA), adrenaline (A) and dopamine (DA), the plasma renin activity (PRA), the aldosterone concentration (PAC) and atrial natriuretic factor (ANF) in plasma, using radioimmunoanalysis, always before and 24 hours after clonidine administration (Haemiton retardR) by the oral route." | 7.68 | [The effect of clonidine on humoral factors in patients with arterial hypertension]. ( Dvoráková, J; Gregorová, I; Horký, K; Kopecká, J; Poliak, M, 1990) |
| "Beta-endorphin (B-Ep), ACTH plasma levels and cortisol serum levels have been evaluated by RIA, in 27 patients suffering from essential blood hypertension and in 20 healthy control subjects." | 7.68 | [Plasma levels of beta-endorphin and ACTH and serum levels of cortisol in different stages of arterial hypertension before and after clonidine therapy]. ( Barletta, C; Scavo, D, 1990) |
| " Furthermore, acute and chronic administrations of clonidine were used to determine a participation of the sympathetic nervous system in the maintenance of hypertension in these patients." | 7.67 | Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine. ( Campese, VM; Levitan, D; Massry, SG; Romoff, M, 1984) |
| " Since clonidine has actually been found to improve renal hemodynamics in patients with essential hypertension, we studied the effects of clonidine therapy in patients with renal transplant hypertension." | 7.67 | Effect of clonidine therapy on renal hemodynamics in renal transplant hypertension. ( Goldman, M; Graybill, A; Green, S; Johnson, M; Mackenzie, T; McClanahan, M; Muakkassa, W; Zawada, ET, 1984) |
| "In ten patients with essential hypertension, 6 weeks of treatment with a clonidine/diuretic combination (1 retard capsule/day, 75 micrograms or 150 micrograms clonidine, and 15 mg chlortalidon) was suddenly discontinued." | 7.67 | [Clonidine-diuretic combination in patients with essential hypertension. Modification of sympathetic activity and blood pressure as well as the reaction following sudden withdrawal]. ( Beckenbauer, UE; Planz, G, 1984) |
| " Thirty subjects with hypertension on hydrochlorothiazide (HCTZ) were randomized to TIAM or CLON." | 7.67 | Withdrawal phenomena in subjects with essential hypertension on clonidine or tiamenidine. ( Hamilton, BP; Hamilton, J; Kuzbida, G; Levinson, P; Mersey, JH; Pavlis, R, 1984) |
| "The comparative efficacy and safety of lofexidine and clonidine in patients with mild to moderate systemic hypertension were evaluated." | 7.67 | Comparative efficacy and safety of lofexidine and clonidine in mild to moderately severe systemic hypertension. ( Lopez, LM; Mehta, JL, 1984) |
| "In 10 patients (aged 46 to 72 years) with essential hypertension (grade III to IV), the acute effects on the haemodynamics in the systemic and pulmonary circulation were analysed following intravenous administration of clonidine." | 7.67 | The haemodynamic effects of clonidine in patients with grade III to IV hypertension. ( Hallier, E; Kuschke, HJ; Mitrović, V, 1986) |
| "Left ventricular mass and function were evaluated by M-mode echocardiography in 10 patients with essential hypertension, before and after 16 weeks of treatment with clonidine." | 7.67 | Clonidine and left ventricular function in ten patients with essential hypertension. ( Velandia Arevalo, J, 1986) |
| "To investigate the possible release of beta-endorphins (beta EN) from tumors and to investigate their possible involvement in the hypotensive mechanism of clonidine (CLO) in pheochromocytoma (PHEO), as compared with essential hypertension (EH), we studied 12 patients with PHEO, 17 patients with uncomplicated stable EH (SEH), nine patients with borderline EH (BEH), and seven healthy volunteers (N)." | 7.67 | Plasma beta-endorphins and catecholamines before and after clonidine in essential hypertension and pheochromocytoma. ( Chodakowska, J; Chojnowski, K; Feltynowski, T; Januszewicz, W; Lazecki, D; Wocial, B, 1987) |
| " Ten patients with essential hypertension underwent non-invasive automatic 24-h blood pressure monitoring three times (baseline and after three and seven days from the application on the upper chest of a transdermal self-adhesive patch delivering clonidine)." | 7.67 | New indices in the evaluation of clonidine transdermal therapy of hypertension. ( Becucci, A; Cinelli, P; de Leonardis, V; de Scalzi, M; Lusini, C, 1989) |
| "Administration of captopril to animals with two-kidney, one clip, renovascular hypertension (RH) lowers the glomerular filtration rate (GFR) in the clipped kidney." | 7.67 | The captopril glomerular filtration rate renogram in renovascular hypertension. ( Frederickson, ED; Phillips, MI; Smith, TB; Wilcox, CS; Williams, CM; Wingo, CD, 1989) |
| "In young men with mild essential hypertension and age-matched normotensive volunteers, plasma concentrations of the endogenous opioid beta-endorphin were determined hourly from 9:00 p." | 7.67 | Clonidine normalizes low plasma beta-endorphin concentration and blood pressure in young men with mild essential hypertension. ( Kraft, K; Stumpe, KO; Theobald, R, 1986) |
| "Arterial blood pressure and central hemodynamic changes were assessed in 44 patients with essential hypertension, uncontrollable by prazosin alone, after propranolol (anaprilin), celiprolol, clonidine (clofelin) or verapamil were added to the treatment schedule." | 7.67 | [Hemodynamic effect of a combination of prazosin with cardiac depressants in the treatment of hypertension]. ( Akopian, LM; Basem, AS; Ivleva, AIa; Krasnobaeva, GM; Moiseev, VS, 1988) |
| "Whether peripheral beta-endorphin contributes to the antihypertensive action of clonidine was examined by measuring plasma levels of beta-endorphin-like immunoreactivity (beta EpLI) after acute administration of clonidine in patients with essential hypertension." | 7.67 | Central alpha-activation by clonidine reduces plasma level of beta-endorphin in patients with essential hypertension. ( Kanayama, Y; Kawarabayashi, T; Kohno, M; Kotsugai, N; Murakawa, K; Sato, K; Takeda, T; Yasunari, K, 1985) |
| "The role of central pressor mechanisms in the maintenance of blood pressure in six hypertensive patients with angiographically proven unilateral renal artery stenosis was investigated by studying the haemodynamic and hormonal responses before and after central sympathetic blockade with clonidine." | 7.67 | Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis. ( Kooner, JS; Mathias, CJ; Peart, S, 1988) |
| ") on clonidine hypotension in 80 patients with essential hypertension revealed that two groups could be separated." | 7.67 | beta-Endorphin and essential hypertension: importance of the clonidine-naloxone interaction. ( Balás-Eltes, A; Farsang, C; Kapocsi, J; Kunos, G; Vajda, L; Varga, K, 1985) |
| "A clonidine suppression test and the measurement of the catecholamine (noradrenaline and adrenaline) concentration in 24-hour urine were undertaken on 13 patients with benign phaeochromocytoma (PCC), 30 patients with benign hypertension (BHT) and ten healthy, normotensive volunteers." | 7.67 | [Diagnostic significance of the clonidine suppression test in suspected pheochromocytoma]. ( Ivens, K; Schürmeyer, T; Stimpel, M; Volkmann, HP; von zur Mühlen, A; Wambach, G, 1988) |
| "We identified eight hypertensive patients who developed severe bradycardia during oral clonidine hydrochloride therapy." | 7.67 | Risk factors for severe bradycardia during oral clonidine therapy for hypertension. ( Byrd, BF; Collins, HW; Primm, RK, 1988) |
| "We have studied the efficacy of clonidine hydrochloride administered transdermally once a week for 9 to 15 weeks in 12 patients with mild to moderate hypertension." | 7.67 | The efficacy of a transdermal formulation of clonidine in mild to moderate hypertension and its effects on the arterial and venous vasculature of the forearm. ( Achimastos, A; Girerd, X; Levenson, J; Pithois-Merli, I; Simon, AC, 1987) |
| "Intravenous clonidine was used to treat systolic hypertension (systolic blood pressure greater than 160 mm Hg) in 15 patients with acute myocardial infarction and documented sympathetic overactivity (high plasma norepinephrine)." | 7.67 | Central inhibition of sympathetic overdrive by clonidine in acute myocardial infarction with systolic hypertension. Haemodynamic study. ( Bernard, R; Liebens, I; Renard, M; Waterschoot, P, 1986) |
| "Pharmacokinetics of clonidine were examined in ten women during pregnancy, in nine during nursing, and in the newborns of these women." | 7.67 | Pharmacokinetics of clonidine during pregnancy and nursing. ( Hartikainen-Sorri, AL; Heikkinen, JE; Koivisto, M, 1987) |
| "Eighty two hypertensive pregnant patients were treated with clonidine during the last trimester of pregnancy." | 7.67 | Clonidine in the treatment of hypertension during pregnancy. ( Kauppila, E; Punnonen, R; Tuimala, R, 1985) |
| "The effectiveness of transdermally administered clonidine in normalizing blood pressure in 22 adolescents with sustained diastolic hypertension was studied." | 7.67 | Transdermal clonidine in the treatment of adolescent hypertension. ( Falkner, B; Lowenthal, DT; Thanki, B, 1985) |
| "The putative role of the central nervous system in the maintenance of elevated blood pressure in patients with essential hypertension (EH) and renal hypertension [unilateral renal parenchymal disease (RPD) and unilateral renal artery stenosis (RAS)] was studied by investigating the cardiovascular and hormonal effects of the predominantly centrally acting sympatholytic agent, clonidine." | 7.67 | Cardiovascular and hormonal effects of clonidine in patients with essential hypertension and renal hypertension. ( Mathias, CJ; Peart, S; Stone, FA; Wilkinson, AH, 1985) |
| "To assess the contribution of sympathetic outflow to blood pressure in patients with essential hypertension, we measured blood pressure and plasma norepinephrine responses to clonidine, an antihypertensive agent that decreases central sympathetic outflow, in 44 patients and in 41 normotensive control subjects of similar age." | 7.67 | Clonidine suppression testing in essential hypertension. ( Goldstein, DS; Keiser, HR; Levinson, PD; Pitterman, A; Stull, R; Zimlichman, R, 1985) |
| "Chronic administration of clonidine in the drinking water of spontaneously hypertensive (SH) rats from 11 through 17 weeks of age prevented the further development of hypertension in this model." | 7.67 | Long term treatment with clonidine during the development of hypertension in spontaneously hypertensive rats. ( Buccafusco, JJ; Serra, M; Smith, LJ; Sussman, AM, 1985) |
| "23 patients presenting with symptoms of pheochromocytoma were subjected to the clonidine suppression test." | 7.67 | Preliminary results with the clonidine suppression test in the diagnosis of pheochromocytoma. ( Beyer, J; Brandstetter, K; Krause, U, 1985) |
| "The antihypertensive effects and side-effects of a clonidine transdermal therapeutic system (clonidine-TTS) were examined over 10 weeks in 22 patients with essential hypertension." | 7.66 | Clonidine through the skin in the treatment of essential hypertension: is it practical? ( Baumgart, P; Boerlin, HJ; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W; Walger, P; Wehling, M, 1983) |
| "Clonidine was administered by intravenous infusion to 12 patients classified as having exaggerated arterial hypertension, their systolic (SAP), diastolic (DAP) and mean (MAP) arterial pressures were significantly reduced from the third min." | 7.66 | Acute hypotensive action of clonidine after intravenous infusion in hypertensive emergencies. ( Fragachán, F; Monsalve, P; Pérez, J; Pérez-Acuña, F; Sanabria, A; Tremarias, A, 1983) |
| "5 mg clonidine (clonidine-TTS) was investigated in 21 patients with essential hypertension over a period of 10 weeks." | 7.66 | [Clonidine transdermal therapeutic system in essential hypertension: effect and tolerance]. ( Baumgart, P; Boerlin, HJ; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W; Walger, P; Wehling, M, 1983) |
| "This study analysed the effects of both seven and 30 days of treatment with clonidine on heart rate, blood pressure (BP), plasma norepinephrine (NE) levels and dopamine-beta-hydroxylase (DBH) activity at rest and after standing in seven patients with essential hypertension." | 7.66 | Effect of clonidine on sympathetic nervous system activity in patients with essential hypertension. ( Chernow, B; Coleman, MD; Lake, CR; Zaloga, GP; Ziegler, MG, 1983) |
| "Two studies of the responses to clonidine as the sole antihypertensive drug in the treatment of mild-to-moderate hypertension are reported." | 7.66 | Hormonal and hemodynamic effects of short- and long-term clonidine therapy in patients with mild-to-moderate hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1983) |
| "In 20 patients with severe hypertension, rapid oral clonidine titration was employed for control of blood pressure, with 0." | 7.66 | Use of oral clonidine for rapid titration of blood pressure in severe hypertension. ( Oguagha, C; Porush, JG; Spitalewitz, S, 1983) |
| "Ten patients with essential hypertension were treated orally with clonidine, and the dose was titrated until the diastolic pressure fell below 90 mm Hg or at least 10 mm Hg below baseline, or until a maximum dose of clonidine of 1." | 7.66 | Plasma clonidine levels in hypertension. ( Barr, J; Maronde, RF; Rho, J; Velasquez, MT, 1983) |
| "The hypotensive effect of nifedipine was studied in 9 patients with severe hypertension." | 7.66 | Management of severe hypertension with nifedipine in combination with clonidine or propranolol. ( Abe, K; Chiba, S; Haruyama, T; Imai, Y; Irokawa, N; Ito, T; Miura, Y; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1980) |
| "A simultaneous analysis of the interrelationships between mean blood pressure (MBP), plasma catecholamines, plasma renin activity (PRA) and aldosterone, exchangeable body sodium, and blood volume was carried out before and after acute and chronic administration of clonidine in 15 patients with essential hypertension, in order to further elucidate the mechanism(s) of action of this drug." | 7.66 | Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension. ( Campese, VM; Massry, SG; Romoff, M; Telfer, N; Weidmann, P, 1980) |
| "Eight patients with essential hypertension were treated with 50 microgram oral clonidine four times daily for 4 wk followed by 75 to 150 microgram four times daily for another 4 to 16 wk." | 7.66 | Plasma clonidine in relation to blood pressure, catecholamines, and renin activity during long-term treatment of hypertension. ( Hökfelt, B; Manhem, P; Paalzow, L, 1982) |
| "1 We have compared, in patients with severe hypertension, the administration of intravenous labetalol by single rapid injection, by repeated bolus injections, and by incremental infusion." | 7.66 | Intravenous labetalol in the treatment of severe hypertension. ( Brown, JJ; Cumming, AM; Lever, AF; Robertson, JI, 1982) |
| "Intra-cisternal clonidine (3 microgram/kg) reduced hypertension and cardiac acceleration after defrenation in dogs, but did not act in intra-venous infusion (10 microgram/kg)." | 7.66 | [Effect of clonidine on three types of experimental hypertension and on plasma renin activity in dogs]. ( Moatti, JP; Montastruc, JL; Montastruc, P, 1978) |
| "11 coronary patients, 8 with mild hypertension, were treated with clonidine, at a dose of 75 micrograms b." | 7.66 | The therapeutic value of clonidine in patients with coronary heart disease. ( Amrein, R; Chu, D; Cocco, G; Haeusler, G; Padovan, GC; Strozzi, C, 1979) |
| "A study of the use of clonidine in the treatment of patients with hypertension, both in hospital and in the community, during a period of 6 years is reported." | 7.66 | Clonidine in hypertension: a 6-year review. ( Keston, M; Lawson, AA, 1979) |
| "Diazoxide, clonidine and labetalol, administered intravenously in fixed doses, were used to treat 30 episodes of severe hypertension in 27 patients." | 7.66 | Comparison of labetalol, clonidine and diazoxide intravenously administered in severe hypertension. ( Kincaid-Smith, P; Thomas, GW; Whitworth, JA; Yeung, CK, 1979) |
| " The mother took clonidine during pregnancy." | 7.66 | Roberts's syndrome and clonidine. ( Beshara, D; Levy, JM; Stoll, C, 1979) |
| "Nineteen patients with severe essential hypertension or hypertension due to renal parenchymal disease were treated with intravenous clonidine." | 7.66 | Evaluation of intravenous clonidine in hypertensive emergencies. ( Niarchos, AP, 1978) |
| "Rebound hypertension occurred in two patients upon clonidine withdrawal." | 7.66 | Hypertension after clonidine withdrawal. ( Batson, HM; deCarvalho, JG; Frohlich, ED; Husserl, FE, 1978) |
| "In order to determine the efficacy and safety of oral clonidine loading to control hypertension rapidly, 15 patients received 0." | 7.66 | Oral clonidine loading for rapid control of hypertension. ( Cohen, IM; Katz, MA, 1978) |
| " Clonidine hydrochloride, an antihypertensive drug believed to directly stimulate brain norepinephrine receptors, was administered to a group of patients with relatively mild Parkinson disease and coexisting essential hypertension and to three patients with Parkinson disease manifesting the "on-off" response to levodopa." | 7.65 | Clonidine in Parkinson disease. ( Marsden, CD; Parkes, JD; Tarsy, D, 1975) |
| " Clonidine-related side effects are still evident, but the overall tolerance profile for this reduced dosage of the drug appears to be favorable." | 6.67 | Low-dose clonidine administration in the treatment of mild or moderate essential hypertension: results from a double-blind placebo-controlled study (Clobass). The Clobass Study Group. ( , 1990) |
| "Nitrendipine is a new calcium antagonist of the 1,4-dihydropyridine group with strong vasodilating properties." | 6.66 | Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate. ( Grosser, KD; Späh, F, 1988) |
| " dosing schedules of clonidine on blood pressure, side-effects and plasma concentration of clonidine were studied in a randomized cross-over study." | 6.65 | Clonidine twice daily in hypertension. Effects of two dosage regimens on blood pressure, side-effects and plasma clonidine concentrations. ( Huikuri, H; Jounela, AJ; Juustila, HJ; Lilja, M; Paalzow, G, 1983) |
| "Nifedipine is a simple, effective, and safe alternative drug for managing hypertensive emergencies, especially when continuous monitoring of the patient cannot be guaranteed." | 6.65 | Nifedipine in hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC; Lang, C; Müller, J; Radü, EW, 1983) |
| "Prazosin was better tolerated, with side effects tending to diminish with time." | 6.64 | Prazosin and clonidine for moderately severe hypertension. ( Hammond, JJ; Kirkendall, WM; Overturf, ML; Thomas, JC; Zama, A, 1978) |
| " The dosage was kept unchanged or increased according to the antihypertensive response." | 6.64 | The use of clonidine and practolol in the treatment of hypertension. ( Ala-Laurila, P; Pitkäjärvi, T; Ruosteenoja, R; Torsti, P, 1976) |
| "Clonidine has clearly been shown to be effective in the treatment of all grades of hypertension." | 6.14 | Clonidine in the treatment of hypertension. ( Garrett, BN; Kaplan, NM, 1980) |
| "This single-centre, prospective trial investigated the use of CST in 60 patients with suspected PPGL associated with out-patient elevations of plasma normetanephrine (NMN) and/or metanephrine (MN), in most cases accompanied with hypertension or an adrenal mass." | 5.51 | Clonidine suppression test for a reliable diagnosis of pheochromocytoma: When to use. ( Dralle, H; Führer, D; Geroula, A; Pamporaki, C; Schmid, KW; Tsiomidou, S; Unger, N; Van Baal, L; Weber, F, 2022) |
| "Current pharmacotherapies for PTSD manage only a subset of these symptoms and typically have adverse side effects which limit their overall effectiveness." | 5.39 | Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. ( Diamond, DM; Fleshner, M; Zoladz, PR, 2013) |
| "Headache was the presenting and most prominent complaint, with daily episodes of short-lasting, intermittent, and paroxysmal attacks." | 5.31 | Recurrent short-lasting headache associated with paroxysmal hypertension: a clonidine-responsive syndrome. ( Dodick, DW, 2000) |
| "Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes." | 5.29 | Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| " It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency." | 5.28 | Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990) |
| "Hypokalemia was found by normal urine excretion of potassium and normal intraerythrocyte potassium contents." | 5.28 | [Hypokalemia caused by nifedipine]. ( Angelova, I; Kundurdzhiev, A; Popiliev, I, 1990) |
| "A major risk associated with the acute treatment of severe hypertension is a reduction in cerebral blood flow (CBF) with ischemic injury to the central nervous system." | 5.28 | Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine. ( Brown, FD; Cervenka, K; Greene, CS; Gretler, DD; McCoy, CE; Murphy, MB, 1990) |
| "Labetalol was administered at the conclusion of surgery as a 20-mg bolus over two minutes followed by 40 mg every 10 minutes until the desired BP was achieved (BP less than or equal to 10% above average preoperative BP or less than 150 mmHg, systolic) or 300 mg had been given." | 5.28 | Intravenous labetalol for the treatment of hypertension after carotid endarterectomy. ( Azad, SS; Goldberg, ME; Larijani, GE; Marr, AT; Seltzer, JL; Smullens, SN, 1989) |
| " However, chronic use of clonidine-TTS was accompanied by a high frequency of contact dermatitis (type IV allergy) in nearly half of our patients (n = 15, 47%)." | 5.27 | Transdermal clonidine application: long-term results in essential hypertension. ( Foerster, E; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W, 1984) |
| "When clonidine was given in a dose of 0." | 5.27 | Interaction of clonidine and labetalol in hypertension. ( Lilja, M, 1983) |
| "Clonidine has been reported to adversely affect glucose tolerance in experimental animals and normal man." | 5.27 | Clonidine in patients with diabetes and mild hypertension. ( Guthrie, GP; Koenig, SH; Kotchen, TA; Miller, RE, 1983) |
| "Clonidine was given orally as monotherapy in increasing daily doses from 3." | 5.27 | Relationship between the cardiovascular effects and steady-state kinetics of clonidine in hypertension. Demonstration of a therapeutic window in man. ( Frisk-Holmberg, M; Paalzow, L; Wibell, L, 1984) |
| "Clonidine was administered intravenously in a dose of 5 micrograms/kg over a 5-min period." | 5.27 | Hemodynamic effects of clonidine in patients with acute myocardial infarction complicated by hypertension. ( Foresti, A; Lotto, A; Massari, FM, 1986) |
| " In Sprague-Dawley rats made hypertensive by chronic administration of deoxycorticosterone pivalate and salt, the hypotensive and bradycardic effects of intra-NTS clonidine were inhibited by ICI 174864, but not by beta-funaltrexamine, a pattern similar to that in SHR, but different from that in normotensive Sprague-Dawley rats." | 5.27 | Opiate receptors and the endorphin-mediated cardiovascular effects of clonidine in rats: evidence for hypertension-induced mu-subtype to delta-subtype changes. ( Kunos, G; Mosqueda-Garcia, R, 1987) |
| "Prazosin has been reported to reduce the hypotensive and/or bradycardic effect of clonidine in various animal models." | 5.27 | Prazosin partly blocks clonidine-induced hypotension in patients with essential hypertension. ( Farsang, C; Kapocsi, J; Vizi, ES, 1987) |
| "Prazosin appears to be a suitable substitute for hydralazine as an effective vasodialator if thiazides plus propranolol or thiazides plus reserpine or alpha-methyldopa are not effective." | 5.26 | Propranolol and newer antihypertensive drugs in the management of hypertension. ( Moser, M, 1979) |
| "28 ng/ml) and plasma half-life (10." | 5.26 | Pharmacokinetic and concentration-effect relationships of clonidine in essential hypertension. ( Davies, DS; Dollery, CT; Neill, EA; Reid, JL; Tippett, P; Wing, LM, 1977) |
| "Among 42 patients converted from clonidine to another antihypertensive medication, few sympathomimetic side effects were observed if the clonidine dosage had been less than 1." | 5.26 | Central nervous system actions of clonidine in hypertension. ( Hoobler, SW; Kashima, T, 1977) |
| "6 Labetalol is a useful addition to the medical treatment of phaeochromocytoma." | 5.26 | Treatment of phaeochromocytoma and of clonidine withdrawal hypertension with labetalol. ( Brown, JJ; Lever, AF; Robertson, AS; Robertson, JI; Rosei, EA; Trust, PM, 1976) |
| "There are limited and nonconcordant data on the rapidity and safety of blood pressure response to clonidine in the setting of asymptomatic severe hypertension." | 5.22 | Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension. ( Ghazi, L; Hanna, J; Peixoto, AJ; Shah, T; Simonov, M; Wilson, FP; Yamamoto, Y, 2022) |
| "To determine the effectiveness of clonidine, compared to captopril, for the treatment of postpartum very high blood pressure in women with hypertension in pregnancy." | 5.17 | Clonidine versus captopril for treatment of postpartum very high blood pressure: study protocol for a randomized controlled trial (CLONCAP). ( Amorim, MM; Coutinho, IC; Katz, L; Maia, SB; Noronha-Neto, C; Souza, AS, 2013) |
| "Of the 50 patients with hypertension (American Society of Anesthesiologists class II), 25 received 2 mL of 2% lidocaine with clonidine (15 μg/mL) and 25 received lidocaine with epinephrine (12." | 5.16 | Is clonidine an adequate alternative to epinephrine as a vasoconstrictor in patients with hypertension? ( Patil, PM; Patil, SP, 2012) |
| "To clarify the effects of bedtime administration of the centrally acting alpha(2)-agonists, guanabenz and clonidine, on morning hypertension." | 5.10 | Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurements. ( Aoki, Y; Araki, T; Chonan, K; Hashimoto, J; Hozawa, A; Imai, Y; Kikuya, M; Matsubara, M; Michimata, M; Nishimura, T; Ohkubo, T; Ugajin, T; Yamaguchi, J, 2003) |
| "Using a randomized double-blind placebo-controlled design, 20 patients with essential hypertension (systolic pressure >160 mm Hg or diastolic pressure >95 mm Hg for > or =1 yr) were assigned to receive clonidine (or placebo), 6 microg/kg orally 120 min before anesthesia and 3 microg/kg intravenously over 60 min before the end of surgery." | 5.09 | Cardiac baroreflex during the postoperative period in patients with hypertension: effect of clonidine. ( Annat, G; Bégou, G; Bonnet, F; Cottet-Emard, JM; Ghignone, M; Hughson, R; Levron, JC; Parlow, JL; Quintin, L; Sagnard, P; Viale, JP, 1999) |
| "Clonidine reduces postoperative circulatory instability in patients with essential hypertension." | 5.09 | The effects of clonidine on sensitivity to phenylephrine and nitroprusside in patients with essential hypertension recovering from surgery. ( Begou, G; Parlow, JL; Quintin, L; Sagnard, P; Viale, JP, 1999) |
| "The objective of this study was to assess the efficacy and tolerability of transdermal clonidine in inner-city African-American and Hispanic-American patients with essential hypertension." | 5.09 | Clinical experience with transdermal clonidine in African-American and Hispanic-American patients with hypertension: evaluation from a 12-week prospective, open-label clinical trial in community-based clinics. ( Dias, VC; Oparil, S; Reilly, PA; Snarr, P; Tendler, B; White, WB, 1999) |
| "We sought to assess the haemodynamic effects of clonidine on left ventricular (LV) pressure-volume relation in patients with diastolic heart dysfunction due to essential hypertension." | 5.09 | Acute effect of clonidine on left ventricular pressure-volume relation in hypertensive patients with diastolic heart dysfunction. ( Dernellis, J; Gavras, H; Gavras, I; Manolis, A; Stefanadis, C; Toutouzas, P; Tsiamis, E; Tsioufis, C, 2001) |
| " In retrospective analyses of the Veterans Affairs Single-Drug Therapy for Hypertension Study, we compared changes in pulse pressure with 6 classes of antihypertensive agents: 1292 men with diastolic blood pressure of 95 to 109 mm Hg on placebo were randomized to receive hydrochlorothiazide, atenolol, captopril, clonidine, diltiazem, prazosin, or placebo." | 5.09 | Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial. ( Cushman, WC; Materson, BJ; Reda, DJ; Williams, DW, 2001) |
| "This report describes the effects of indapamide versus transdermal clonidine on left ventricular hypertrophy (LVH) in hypertensive diabetic patients." | 5.08 | Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients. ( Berk, LS; Tan, LG; Tan, SA, 1996) |
| "Patients with mild to moderate hypertension (diastolic blood pressure, 95 to 109 mm Hg) were randomly allocated to treatment with atenolol, captopril, clonidine, diltiazem, hydrochlorothiazide, or prazosin in a double-masked trial." | 5.08 | Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. ( Anderson, RJ; Gottdiener, JS; Massie, BM; Materson, BJ; Reda, DJ; Williams, DW, 1997) |
| "Transdermal clonidine (TTSC) treatment was evaluated in 29 patients with mild to moderate hypertension scheduled for minor surgery." | 5.08 | Usefulness of transdermal clonidine in hypertensive patients undergoing minor surgical operations. ( Airoldi, G; Clavario, P; Copello, F; De Martini, M; Martinengo, E; Massari, D; Pedevilla, M; Pini, A; Trucco, U, 1998) |
| "A double-blind, double-dummy, parallel-group trial that used a predominantly Hispanic patient population with mild-to-moderate hypertension was designed to compare the efficacy, safety, and acceptability of monotherapy with either transdermal clonidine applied once a week or terazosin tablets taken once a day." | 5.08 | Alpha 2-agonist versus alpha 1-antagonist in mild-to-moderate hypertension: comparison of transdermal clonidine and terazosin monotherapies. ( Alvarez, C; Harris, SI, 1997) |
| "A rapid increase in isoflurane concentration can induce tachycardia and hypertension and increase plasma catecholamine concentrations." | 5.07 | Clonidine and lidocaine inhibition of isoflurane-induced tachycardia in humans. ( Namba, H; Namiki, A; Tanaka, S; Tsuchida, H, 1994) |
| "The efficacy and safety of two different galenic formulations of transdermal clonidine systems were compared in 905 patients with mild to moderate essential hypertension during a 12 weeks observation period." | 5.07 | Efficacy and safety of two different galenic formulations of a transdermal clonidine system in the treatment of hypertension. ( Göbel, BO; Kolloch, RE; Mehlburger, L; Schumacher, H, 1993) |
| "The clonidine patch offers for the first time the unique possibility of a once-a-week transdermal therapy of hypertension due to direct absorption of clonidine through the skin." | 5.07 | One year efficacy and tolerability of clonidine administered by the transdermal route in patients with mild to moderate essential hypertension--a multicentre open label study. The Antihypertensive Patch Italian Study (APIS) Investigators. ( , 1993) |
| "The long-term safety and efficacy of transdermal clonidine (C-TTS) was evaluated in 102 patients with mild to moderate hypertension over a mean treatment period of 4." | 5.07 | Long-term (5 year) experience with transdermal clonidine in the treatment of mild to moderate hypertension. ( Breidthardt, J; Mehlburger, L; Schumacher, H, 1993) |
| "This study was designed to compare the clinical efficacy and safety of oral clonidine and oral labetalol in the treatment of severe hypertension in an emergency department setting." | 5.07 | Oral labetalol versus oral clonidine in the emergency treatment of severe hypertension. ( Atkin, SH; Beaty, P; Cuffie, C; Jaker, MA; Quadrel, MA; Soto-Greene, ML, 1992) |
| "The central alpha-2-adrenergic receptor agonist, clonidine (300 micrograms daily) significantly increased the plasma beta-endorphin-like immunoreactivity (beta ELI) in 12 patients with mild to moderate essential hypertension in a randomized, crossover study." | 5.07 | Adrenergic and dopaminergic regulation of circulating beta-endorphin-like immunoreactivity in hypertension. ( Alföldi, A; Farsang, C; Fekete, MI; Simkó, K, 1991) |
| "In 10 patients with moderate essential hypertension, the neurohumoral and hemodynamic effects of 4 days' treatment with 2 x 75 micrograms clonidine (C), 2 x 20 mg nifedipine retard (N), and a combination of the two (C/N) were studied and compared with baseline values." | 5.07 | [Nifedipine-clonidine combination in essential hypertension. Hemodynamic and neurohumoral findings of the combination in comparison with the effect of the individual substances]. ( Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V, 1991) |
| "This double-blind, double-dummy, randomized clinical trial, conducted in elderly patients with mild hypertension, compared adherence to treatment, efficacy, side effects, and quality of life during treatment with transdermal clonidine versus oral sustained-release verapamil (verapamil-SR)." | 5.07 | Therapeutic adherence in the elderly: transdermal clonidine compared to oral verapamil for hypertension. ( Burris, JF; Cook, ME; Papademetriou, V; Wallin, JD; Weidler, DJ, 1991) |
| "Forty-four patients with arterial hypertension of any cause were selected and randomly divided in three groups: P group, consisting of 9 patients who received placebo; N group, consisting of 17 patients, 8 males, mean age of 47 years who received 10 mg of sublingual nifedipine; C group, consisting of 18 patients, 6 males, with mean age of 47 years who received 0." | 5.07 | [Acute reduction of blood pressure: comparative study of nifedipine and clonidine]. ( Abzaid, A; de Castro, EG; Dondici Filho, J; Gomes, JC; Luz, NS, 1991) |
| "The antihypertensive efficacy and side effects of transdermal clonidine (Catapres-TTS) and oral clonidine in equivalent doses on a weight basis were compared under double blind (double dummy) and cross over conditions in 16 outpatients with mild to moderate hypertension." | 5.07 | Transdermal and oral clonidine. ( Jounela, AJ; Juustila, H; Lilja, M; Sarna, S, 1991) |
| "The study objective was to determine the effects of monotherapy with clonidine and atenolol versus placebo on serum lipids, apolipoproteins, and blood pressure in patients with mild primary hypertension." | 5.06 | The effects of clonidine hydrochloride versus atenolol monotherapy on serum lipids, lipid subfractions, and apolipoproteins in mild hypertension. ( Bradley, CA; Burger, C; Hays, JT; Houston, MC; Nadeau, J; Olafsson, L; Swift, L, 1990) |
| "To evaluate the role of the sympathetic nervous system in essential hypertension and the influence of clonidine, 28 male subjects with mild to moderate hypertension were either treated with low-dose clonidine (n = 14, mean age: 42." | 5.06 | Hemodynamic and neurohumoral effects of low-dose clonidine in mild to moderate hypertension. ( Rüddel, H; Schmieder, R; Schulte, W; von Eiff, AW, 1987) |
| " oral propranolol (OP) was evaluated in 32 patients with mild essential hypertension (mean BP 150/95 mm Hg)." | 5.06 | Randomized, double-blind comparison of transdermal clonidine with oral propranolol. ( Dobak, JD; Franklin, SS; Kirschenbaum, MA; Tonkon, MJ, 1987) |
| " Twenty-one patients with mild to moderate hypertension were randomly assigned to nitrendipine (n = 10) and to verapamil treatment for 4 weeks." | 5.06 | Short- and long-term cerebrovascular effects of nitrendipine in hypertensive patients. ( Conen, D; Müller, J; Noll, G; Rüttimann, S; Schneider, K, 1988) |
| "We compared the effects of transdermal clonidine and oral atenolol on acute exercise performance and on conditioning response to an 8-week program of regular aerobic exercise in young, otherwise healthy subjects with mild hypertension." | 5.06 | Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension. ( Davidman, M; Davies, SF; Graif, JL; Husebye, DG; Iber, C; Maddy, MM; McArthur, CD; O'Connell, MB; Path, MJ, 1989) |
| " Sixty middle-aged men with mild-to-moderate essential hypertension never previously treated were treated either with low-dose clonidine (n = 10), oxprenolol (n = 20), nitrendipine (n = 20) or enalapril (n = 10)." | 5.06 | Efficacy of four antihypertensive drugs (clonidine, enalapril, nitrendipine, oxprenolol) on stress blood pressure. ( Bähr, M; Langewitz, W; Rüddel, H; Schächinger, H; Schmieder, RE; Schulte, W, 1989) |
| "The antihypertensive effectiveness and the clinical and biochemical safety of cicletanine were evaluated in 84 patients (28 women, 56 men) presenting with permanent essential hypertension without severe cardiovascular complications." | 5.06 | [Cicletanine administered with other antihypertensive agents]. ( Deschamps de Paillette, E; Grimberg, D; Tarrade, T, 1989) |
| " To investigate the contribution of sedation to the cardiovascular effects induced by clonidine, we studied patients with essential hypertension on two separate occasions when similar levels of sedation were induced by clonidine and nitrazepam." | 5.06 | The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension. ( Kooner, JS; Mathias, CJ; Peart, WS, 1989) |
| "The role of alpha 2-adrenoceptor stimulation by clonidine on the secretion of beta-endorphin, ACTH, and cortisol in essential hypertension and obesity was studied in 45 subjects: 15 non-obese hypertensives, 10 obese hypertensives, 11 obese normotensives, and 9 healthy subjects." | 5.06 | Effect of clonidine on beta-endorphin, ACTH and cortisol secretion in essential hypertension and obesity. ( Jeske, W; Puciłowska, J; Soszynski, P; Słowinska-Srzednicka, J; Wierzbicki, M; Zgliczynski, S, 1988) |
| "Fifty-one patients with urgent hypertension were treated in the emergency department with either oral nifedipine or oral clonidine in a randomized double-blind prospective study." | 5.06 | Oral nifedipine vs oral clonidine in the treatment of urgent hypertension. ( Atkin, S; Brosch, F; Jaker, M; Schmid, G; Soto, M, 1989) |
| "Twenty patients with type II diabetes mellitus and hypertension (WHO stages I and II) participated in a 3-month double-blind cross-over study to evaluate the effects of clonidine (75-300 micrograms daily) on blood pressure, glycemic control and plasma lipoproteins." | 5.06 | Lipoproteins and metabolic control in hypertensive type II diabetics treated with clonidine. ( Ekberg, M; Fridström, P; Lins, LE; Nilsson-Ehle, P; Ursing, D, 1988) |
| " Middle aged male caucasian patients with hitherto untreated mild essential hypertension were given nitrendipine 10-20 mg per day, oxprenolol 160 mg per day or clonidine 75-300 micrograms per day until casual blood pressure was below 140/90 mmHg for at least three months." | 5.06 | Impact of antihypertensive therapy on blood pressure reactivity during mental stress. ( Langewitz, W; Rüddel, H; Schmieder, R; Schulte, W, 1988) |
| "We evaluated the safety and efficacy of transdermal clonidine (TC) in 23 patients with essential hypertension over a two-year period." | 5.06 | Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension. ( Horning, JR; McNulty, R; Simmons, JL; Williams, L; Zawada, ET, 1988) |
| "In a six-week multicenter, double-blind comparison study, moxonidine and clonidine HCl were tested in 122 and 30 outpatients, respectively, with mild to moderate hypertension (World Health Organization stage I and II; highest measured diastolic blood pressure, 90 to 115 mm Hg)." | 5.06 | Comparison of moxonidine and clonidine HCl in treating patients with hypertension. ( Plänitz, V, 1987) |
| "Guanfacine, an alpha 2-adrenoceptor agonist, was compared with clonidine as step-2 therapy of mild to moderate essential hypertension in a 24-week, double-blind, randomized, parallel evaluation to determine efficacy, safety and occurrence of withdrawal syndrome." | 5.06 | Comparison of guanfacine versus clonidine for efficacy, safety and occurrence of withdrawal syndrome in step-2 treatment of mild to moderate essential hypertension. ( Bedsole, G; Fillingim, J; Hall, D; Haring, O; Jagger, P; Lewin, A; McMahon, FG; Roginsky, M; Stepansky, W; Wilson, MF, 1986) |
| "In 30 patients with mild essential hypertension, clonidine hydrochloride was delivered from a skin patch reservoir designed to release medication at a constant rate for seven days." | 5.06 | Transdermal clonidine in mild hypertension. A randomized, double-blind, placebo-controlled trial. ( Daugirdas, JT; Hano, JE; Hockenberry, B; Ing, TS; Neubauer, JA; Popli, S, 1986) |
| "The effectiveness of transdermally administered clonidine using Catapres-TTS patches applied once a week was assessed in the control of mild to moderate hypertension by 16 general practitioners in 135 subjects." | 5.06 | A community-based trial of transdermal antihypertensive therapy with clonidine (Catapres-TTS). ( Kellaway, GS; Lubbe, WF, 1986) |
| "Self-adhesive patches containing a 7-day supply of transdermal clonidine were used to treat twenty patients with mild essential hypertension." | 5.05 | Transdermal continuous antihypertensive therapy. ( Brewer, DD; Drayer, JI; Lipson, JL; Weber, MA, 1984) |
| "The effect of naloxone on the hypotensive and bradycardiac action of clonidine was studied in 27 hospitalized patients with uncomplicated mild-to-moderate essential hypertension." | 5.05 | Possible involvement of an endogenous opioid in the antihypertensive effect of clonidine in patients with essential hypertension. ( Farsang, C; Juhasz, I; Kapocsi, J; Kunos, G, 1982) |
| " This study investigates the effects of acute and chronic mianserin administration in patients with essential hypertension established on long term treatment with either clonidine or methyldopa." | 5.05 | Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients. ( Elliott, HL; McLean, K; Reid, JL; Sumner, DJ, 1983) |
| " In the present study the effect of the opiate receptor blocker naloxone on the reduction of blood pressure and plasma noradrenaline induced by the alpha 2-agonist clonidine was investigated in nine patients with essential hypertension." | 5.05 | Failure of naloxone to reduce the clonidine induced reduction of blood pressure and plasma noradrenaline in patients with essential hypertension. ( Bramnert, M; Hökfelt, B, 1983) |
| " In the present study the effect of the opiate receptor blocker naloxone on the increase in plasma GH induced by clonidine was investigated in eight patients with essential hypertension." | 5.05 | Partial blockade by naloxone of clonidine-induced increase in plasma growth hormone in hypertensive patients. ( Bramnert, M; Hökfelt, B, 1984) |
| "24 mg/day) and propranolol (average 105 mg/day) on home blood pressure readings in 16 patients with borderline hypertension was investigated in a randomized, double-blind, placebo crossover design." | 5.05 | Use of clonidine and propranolol as monotherapy in borderline hypertension. ( Cottier, C; Julius, S, 1983) |
| "We measured the first dosage effect and the long-term effect of lofexidine on blood pressure, heart rate, plasma catecholamines, and their major metabolites in 16 patients with primary hypertension who were receiving 50 mg hydrochlorothiazide twice a day while they were recumbent and upright and during isometric handgrip contraction." | 5.05 | Hemodynamic effect of lofexidine with a diuretic in hypertension. ( Alexander, N; Maronde, RF; Velasquez, M; Vlachakis, ND, 1983) |
| "The effects of clonidine, naloxone, and their combination on arterial blood pressure (BP), heart rate (HR), and hemodynamic and biochemical parameters were examined in 29 patients with essential hypertension." | 5.05 | Reversal by naloxone of the antihypertensive action of clonidine: involvement of the sympathetic nervous system. ( Farsang, C; Fekete, M; Kapocsi, J; Kunos, G; Malisak, Z; Vajda, L; Varga, K, 1984) |
| "5 mg of slow-release (sr) clonidine, 800 mg of acebutolol, and of both drugs combined on blood pressure and the water-salt balance were compared in 10 patients with essential hypertension." | 5.05 | Clonidine, acebutolol and their interaction in essential hypertension: effects on blood pressure and the control of water and electrolyte balance. ( Cornette, M; Degoulet, P; Fermé, I; Ménard, J; Plouin, PF, 1983) |
| "The antihypertensive drug, clonidine, was administered to 18 patients, 8 females and 10 males, with WHO grade I-II essential hypertension in two forms, either as sustained-release depot capsule of 250 micrograms once daily or as standard clonidine preparation, 150 micrograms twice daily." | 5.05 | Comparison of sustained-release and standard preparations of clonidine in essential hypertension. ( Fyhrquist, F, 1983) |
| "The efficacy of transdermal clonidine, alone and in combination with diuretics, has been demonstrated in several studies involving patients with mild to moderate essential hypertension." | 5.05 | Clinical experience with rate-controlled delivery of antihypertensive therapy by a transdermal system. ( Drayer, JI; Weber, MA, 1984) |
| "The effectiveness of transdermally administered clonidine hydrochloride was evaluated in a multicenter study in 85 patients with mild essential hypertension." | 5.05 | Transdermal administration of clonidine for treatment of high BP. ( Drayer, JI; Hamburger, R; Kirk, LN; McMahon, FG; Shah, AR; Weber, MA, 1984) |
| "The acute and chronic effects of fixed dosages of clonidine and prazosin on supine and upright blood pressure, the renin-angiotensin-aldosterone system, and plasma catecholamines were compared in 24 patients with essential hypertension." | 5.05 | Comparative antihypertensive and endocrinologic effects of clonidine and prazosin in patients with essential hypertension. ( Drayer, JI; Hubbell, FA; Rose, DE; Weber, MA, 1984) |
| "3 mg clonidine and 3 mg guanfacine were equiactive in decreasing blood pressure and heart rate in 17 subjects with essential hypertension." | 5.05 | Effects of clonidine and guanfacine in essential hypertension. ( Alföldi, S; Farsang, C; Kapocsi, J; Vajda, L; Varga, K, 1984) |
| "A double-blind crossover trial was undertaken to compare the efficacy of sustained-release clonidine and long-acting propranolol in the treatment of 20 patients (8 males and 12 females) with sustained hypertension." | 5.05 | Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension. ( Lawson, AA; Rodrigues, E, 1982) |
| "Patients over 60 years of age (M = 70 years) with the predominant systolic form of essential hypertension (systolic blood pressure greater than 160 mm Hg; diastolic blood pressure less than 100 mm Hg) were treated with a combination of low doses of the diuretic chlorthalidone and the centrally-acting sympatholytic agent clonidine." | 5.05 | Effects of low-dose antihypertensive therapy in elderly patients with predominant systolic hypertension. ( Drayer, JI; Gray, DR; Weber, MA, 1983) |
| "Nine patients with hypertension were given xipamide 40 mg orally as monotherapy on alternate days." | 5.05 | Clinical trial of xipamide in the treatment of hypertension. ( Antonelli, S; Lentini, S; Leone, G; Paoletti, V, 1980) |
| "A single evening dose of a clonidine-chlorthalidone combination (Combipres) was compared with the usual twice-daily schedule in 11 patients with essential hypertension." | 5.05 | Blood pressure response to a single daily dose of a clonidine-chlorthalidone combination. ( Grossman, SH; Gunnells, JC, 1980) |
| " Sixteen patients with essential hypertension were treated with guanfacine and with clonidine for 5 weeks each in a double-blind, placebo-controlled, cross-over trial." | 5.05 | Antihypertensive effect of guanfacine: a double-blind cross-over trial compared with clonidine. ( Distler, A; Kirch, W; Lüth, B, 1980) |
| "The antihypertensive and clinical effects of two centrally acting drugs, guanabenz and clonidine, were compared in a double-blind trial in 29 patients with established hypertension." | 5.05 | Comparison of guanabenz and clonidine in hypertensive patients. ( Kluyskens, Y; Snoeck, J, 1980) |
| "Sixteen patients with chronic hypertension (grade I-II WHO classification) who had been successfully treated with clonidine (Catapresan Depot Perlongetten), received a placebo capsule on the second, third or fourth day of a five-day trial period." | 5.05 | [Duration of effectiveness of clonidine-depot: a double-blind trial (author's transl)]. ( Steger, W, 1980) |
| "In a multicenter study with 54 patients with essential and renal hypertension (WHO I to III) the antihypertensive efficacy and safety of guanfacine were evaluated against clonidine in a double blind cross-over design." | 5.05 | [A new antihypertensive agent used in a clinical setting]. ( Kaiser, HJ; Raschig, A; Wetzels, E, 1980) |
| "The antihypertensive and side effects of guanfacine and clonidine were compared in 24 patients with essential hypertension in a single-blind crossover study." | 5.05 | Evaluation of guanfacine and clonidine in essential hypertension: a single-blind crossover study. ( Louis, WJ; Miach, PJ, 1980) |
| "The efficacy, safety, and tolerability of lofexidine, a centrally acting imidazoline derivative, were compared to that of clonidine in a randomized double-blind trial in 28 patients with moderate essential hypertension." | 5.05 | Lofexidine and clonidine in moderate essential hypertension. ( Dustan, HP; Oparil, S; Smith, LR; Wilkins, LH; Winternitz, SR, 1981) |
| "The effects of clonidine and minoxidil on sympathetic nervous activity has been studied in 10 patients with accelerated or resistant hypertension." | 5.05 | Effect of minoxidil on sympathetic nervous activity in clonidine-treated hypertensive patients. ( Aliendres, R; Hernández, E; Hernández-Pieretti, O; Morillo, J; Ramírez, A; Urbina-Quintana, A; Velasco, M, 1981) |
| "The effects of metropolol (beta 1-selective), propranolol (nonselective) and clonidine (central alpha-stimulant) on plasma norepinephrine, blood pressure and heart rate were assessed at rest, during isometric work and dynamic exercise in 15 patients with moderate hypertension." | 5.05 | Response of blood pressure and plasma norepinephrine to propranolol, metoprolol and clonidine during isometric and dynamic exercise in hypertensive patients. ( Frick, MH; Jänne, J; Virtanen, K, 1982) |
| "The effectiveness and tolerance of a centrally acting antihypertensive agent (clonidine) was compared to that of a diuretic (hydrochlorothiazide) in treatment of adolescents with essential hypertension." | 5.05 | Effectiveness of centrally acting drugs and diuretics in adolescent hypertension. ( Affrime, MB; Falkner, B; Lowenthal, DT; Onesti, G, 1982) |
| "A 12-week crossover study was carried out in 24 patients with chronic hypertension to compare the effect of clonidine given in a sustained-release form with that of a standard tablet." | 5.05 | Treatment of hypertensive out-patients with a sustained-release dosage form of clonidine: a comparison with standard tablet therapy and long-term follow-up study. ( Steger, W, 1980) |
| "The antihypertensive effects of urapidil and clonidine have been studied in a double-blind cross-over trial in 11 hypertensive outpatients with mild to moderate hypertension, at rest and during isometric exercise." | 5.05 | Antihypertensive effects of urapidil and clonidine: a double-blind cross-over study. ( Heikkilä, O; Jääskeläinen, T; Jounela, AJ; Kanniainen, E; Lilja, M, 1985) |
| "A prospective, double-blind, randomized controlled trial was carried out, comparing alpha-methyldopa and clonidine hydrochloride in 100 pregnant women with hypertension." | 5.05 | Clonidine hydrochloride--a safe and effective antihypertensive agent in pregnancy. ( Child, A; Henderson-Smart, DJ; Horvath, JS; Korda, A; Phippard, A; Tiller, DJ, 1985) |
| "Fifty-nine patients with primary hypertension, WHO stages I and II, participated in a 6-month multicentre, single-blind study to evaluate the effects of small doses of clonidine (75-300 micrograms daily) on blood pressure (BP) and serum lipoproteins." | 5.05 | Clonidine in mild to moderate hypertension: effects on blood pressure and serum lipoproteins. ( Karlberg, BE; Lins, LE; Rössner, S, 1985) |
| "1 A double-blind cross over trial between clonidine, propranolol and a placebo in patients with moderate hypertension has been performed." | 5.04 | A comparative trial of clonidine, propranolol and placebo in the treatment of moderate hypertension. ( Raftery, EB; Wilkinson, PR, 1977) |
| "Sixteen patients with essential hypertension were treated with N-Amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride (BS 100--141) and clonidine for five weeks each in a double-blind cross-over trial." | 5.04 | Antihypertensive effect of N-amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride. A double-blind cross-over trial versus clonidine. ( Distler, A; Kirch, W, 1978) |
| "Fourty-six men and 6 women aged 45 years and having arterial hypertension newly diagnosed at routine medical examinations were given out-patient antihypertensive treatment with prazosin, prazosin + hydrochlorothiazide, or prazosin + hydrochlorothiazide + clonidine." | 5.04 | Antihypertensive drug combinations: prazosin, hydrochlorothiazide and clonidine. ( Kontro, J; Kyöstilä, S; Mattila, MJ; Pitkäjärvi, T, 1977) |
| "The antihypertensive efficacy and safety of guanabenz were evaluated against clonidine in two groups of 18 patients with uncomplicated essential hypertension." | 5.04 | Evaluation of the efficacy and safety of guanabenz versus clonidine. ( Asmal, AC; Leary, WP; Williams, PC, 1979) |
| "Three dosage combinations of clonidine and cyclothiazide were tested in at least 20 patients each, under clinical (4 weeks) and oupatients (longterm) conditions, in order to find a suitable combination with fewer side effects than the single drugs with at least equal efficacy for the longterm treatment of hypertension." | 5.04 | [Clinical trial of a combination preparation of clonidine and cyclothiazide (author's transl)]. ( Wimmer, PP, 1977) |
| "In 20 patients with mild to moderate hypertension, the effects of abrupt cessation of clonidine therapy on blood pressure, heart rate and catecholamine excretion were evaluated." | 5.04 | Abrupt cessation of clonidine administration: a prospective study. ( Anton, AH; Chrysant, SG; Dillard, BL; Whitsett, TL, 1978) |
| " Propranolol was given to eight haemodialysed patients with resistant arterial hypertension for periods ranging from 6 to 16 months." | 5.04 | Long-term propranolol treatment of resistant arterial hypertension in haemodialysed patients. ( Biagini, M; Maggiore, Q; Misefari, M; Zoccali, C, 1975) |
| "The purpose of this paper is to report our experience and to review the published data on the diagnostic significance and risks of the clonidine suppression test in the diagnosis of pheochromocytoma." | 4.80 | Clonidine suppression test revisited. ( Geiger, H; Lenz, T; Ross, A; Schulte, KL; Schumm-Draeger, P, 1998) |
| " In a long-term (4 weeks) double-blind cross-over study in essential hypertension, rilmenidine was well tolerated and had similar effects to those of atenolol on erect and supine blood pressure." | 4.79 | Clinical pharmacology of drugs acting on imidazoline and adrenergic receptors. Studies with clonidine, moxonidine, rilmenidine, and atenolol. ( Elliott, HL; MacPhee, G; Panfilov, V; Reid, JL, 1995) |
| "The I1-imidazoline receptor is a specific high-affinity binding site corresponding to a functional cell-surface receptor mediating the antihypertensive actions of moxonidine and other second-generation centrally-acting agents, and may play a role in countering insulin resistance in an animal model of metabolic syndrome X." | 4.79 | The I1-imidazoline receptor: from binding site to therapeutic target in cardiovascular disease. ( Ernsberger, P; Friedman, JE; Koletsky, RJ, 1997) |
| " Drugs that enhance central alpha 2 activity, such as clonidine, guanfacine and the active metabolite of methyldopa, can significantly lower BP and are effective in the long-term control of hypertension, either alone or in combination with other drugs." | 4.77 | Alpha-adrenergic receptors and blood pressure control. ( Reid, JL, 1986) |
| " It has also been used intravenously in phaeochromocytoma, tetanus, clonidine withdrawal, and as an adjunct to halothane to produce hypotensive anaesthesia." | 4.76 | Combined alpha- and beta-receptor inhibition in the treatment of hypertension. ( Prichard, BN, 1984) |
| "To assess the hemodynamic effects of Clonidine in hypertensive patients (pts) with an acute myocardial infarction (AMI), we administered the drug to 12 such patients either in a single bolus (75--150 micrograms in 5 min - 8 pts) or by continuous infusion (0." | 4.76 | [Hemodynamic effects of intravenous clonidine in patients with acute myocardial infarction]. ( Foresti, A; Lotto, A; Massari, FM; Moglia, F, 1982) |
| " Sitagliptin and clonidine are effective curing drugs for controlling diabetes and hypertension, while insulin and norepinephrine are the biomarkers of these two diseases." | 4.12 | Chiral Luminescent Sensor Eu-BTB@d-Carnitine Applied in the Highly Effective Ratiometric Sensing of Curing Drugs and Biomarkers for Diabetes and Hypertension. ( Ding, B; Huo, J; Jiang, YP; Liu, YY; Shi, YF; Sun, PP; Wang, K; Wang, XR; Wang, XZ; Zhang, ZQ; Zhu, NJ, 2022) |
| "The agonists of alpha(2)-adrenergic receptors such as clonidine, rilmenidine or monoxidine are known to lower blood pressure (BP) through a reduction of brain sympathetic outflow but their chronic antihypertensive effects in rats with low-renin or high-renin forms of experimental hypertension were not studied yet." | 4.12 | Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension. ( Behuliak, M; Řezáčová, L; Vaněčková, I; Zicha, J, 2022) |
| "Amphetamine toxicity typically presents with hypertension and tachycardia." | 4.02 | Amphetamine and Clonidine Toxicity Resulting in Posterior Reversible Encephalopathy Syndrome. ( Dvorak, P; Minhaj, FS; Nacca, N; Schult, RF, 2021) |
| "Borderline isolated norepinephrine (NE) and normetanephrine (NMT) elevation is common among patients with suspected pheochromocytoma and paraganglioma (PPGL)." | 3.96 | The association between systolic blood pressure reduction during clonidine suppression testing and the decrease in plasma catecholamines and metanephrines. ( Fishman, B; Golani, T; Grossman, E; Leibowitz, A; Olswang-Kutz, Y; Sharabi, Y; Shlomai, G, 2020) |
| " Hypertension failed to be controlled with multiple doses of oral clonidine and intravenous labetalol." | 3.91 | Hypertensive Urgency: An Undesirable Complication of a "Male Performance" Herbal Product. ( Prescott, A; Smereck, J, 2019) |
| "The primary objective was to achieve decreased rates of clonidine orders for immediate treatment of asymptomatic hypertension in the office." | 3.83 | Implementing a Policy and Protocol on Managing Patients With Hypertensive Urgencies. ( Chim, C; Dimitropoulos, E; Ginzburg, R, 2016) |
| "Oral clonidine is used to treat hypertension but often produces sedation and severe dry mouth; intrathecal clonidine is used to treat chronic pain but may produce hypotension." | 3.81 | Intrathecal Clonidine via Lumbar Puncture Decreases Blood Pressure in Patients With Poorly Controlled Hypertension. ( D'Angelo, R; Hildebrand, KR; Hong, KS; Komanski, CB; North, JM; Rauck, RL, 2015) |
| " The authors identified children with ≥1 clonidine prescription; the authors examined their ICD-9 diagnoses categorized as simple and complex attention deficit hyperactivity disorder (ADHD), non-ADHD mental health disorder, hypertension, or others." | 3.78 | Clonidine utilization trends for Medicaid children. ( Clark, SJ; Cohn, L; Kershaw, D; Rocchini, A; Yoon, EY, 2012) |
| "In order to elucidate the involvement of the brain renin-angiotensin system (RAS) in cadmium intracerebroventricular (ICV) hypertension, we evaluated the effects of a pretreatment with different drugs: clonidine, an alpha(2) adrenergic agonist, enalapril and captopril, both ACE inhibitors, and saralasin, a competitive nonselective AT(1) and AT(2) receptor antagonist." | 3.76 | Brain renin-angiotensin system modifies the blood pressure response to intracerebroventricular cadmium in rats. ( Anania, V; Antuofermo, E; Baralla, E; Deiana, G; Demontis, MP; Macciotta, NP; Palomba, D; Varoni, MV, 2010) |
| " Even when drug-resistance appears to be responsible for the failure to control secondary hypertension in AS, clonidine may represent a safe, effective option in the normalization of high blood pressure." | 3.76 | Ventricular septal defect in a child with Alport syndrome: a case report. ( Bassareo, PP; Marras, AR; Mercuro, G, 2010) |
| "Clonidine reduced pretreatment BP and CSF NE levels by 27% (p less than 0." | 3.76 | Cerebrospinal fluid norepinephrine levels in essential hypertension: effects of drug treatment and withdrawal. ( Cubeddu, LX; Hoffman, IS, 1987) |
| "The objective of this study was to determine the pharmacokinetic parameters of clonidine during pregnancy compared with previously published data in nonpregnant subjects." | 3.75 | Clonidine pharmacokinetics in pregnancy. ( Buchanan, ML; Carr, DB; Easterling, TR; Hebert, MF; Mattison, DR; Nelson, WL; Risler, LJ; Shen, DD, 2009) |
| "A 68-year-old woman developed eosinophilic pleural effusion and systemic eosinophilia 2 months after starting antihypertensive therapy with diltiazem." | 3.74 | Diltiazem-induced eosinophilic pleural effusion. ( Akritidis, N; Katsanou, A; Koutsouka, F; Pappas, G; Petrakis, D; Raptis, L, 2007) |
| " Here, upon immobilization combined with emergence from anesthesia in rats and clonidine administration, pressure lability was quantitatively assessed and related to baroreflex sensitivity." | 3.74 | Reduced blood pressure lability during emergence from anaesthesia in rats: a pilot study using clonidine. ( Cividjian, A; Quintin, L; Rentero, N, 2008) |
| "Clonidine prevented the L-NNA induced hypertension dose-dependently, but did not effect the heart rates decreased by L-NNA." | 3.74 | [Clonidine prevents development of hypertension in N (omega)-nitro-L-arginine-treated rats]. ( Aksulu, HE; Ilhan, S; Oktar, S, 2008) |
| "Transdermal clonidine was approved by the US Food and Drug Administration in 1984 for the treatment of mild-to-moderate hypertension alone or in combination with a diuretic." | 3.73 | Transdermal clonidine: therapeutic considerations. ( Grubbs, R; Sica, DA, 2005) |
| "Clonidine-induced delirium has rarely been reported." | 3.73 | Clonidine-induced delirium. ( Delaney, J; Doddamani, S; Ostfeld, R; Spevack, D, 2006) |
| "Abrupt withdrawal from clonidine therapy is a well-known cause of hyperadrenergic symptoms, but reports of acute myocardial infarction are extremely rare." | 3.72 | Acute myocardial infarction as a complication of clonidine withdrawal. ( Gifford, W; Goldberg, R; Kishineff, S; Simic, J, 2003) |
| "Problem of clofellinum (clonidine) usage in premedication in aged persons with arterial hypertension is discussed." | 3.72 | [Arterial hypertension intraoperative management in aged patients by different premedication variants]. ( Proshchaev, KI, 2004) |
| "To report a case of possible clonidine-induced hypertension (by Naranjo score) in a patient with a C4 spinal lesion." | 3.71 | Clonidine-induced hypertension in a patient with a spinal lesion. ( Backo, AL; Clause, SL; Gibbs, KA; Triller, DM, 2002) |
| "The role that the central sympathetic nervous system plays in the development of obesity hypertension and insulin was evaluated by feeding dogs a high fat diet with or without clonidine treatment." | 3.70 | Clonidine prevents insulin resistance and hypertension in obese dogs. ( Babu, K; Mao, HZ; Marker, P; Rocchini, AJ; Rocchini, AP, 1999) |
| "Clonidine, an alpha2 agonist, was administered through a nasogastric tube for the treatment of hypertension in a head-injury patient with elevated plasma catecholamines." | 3.70 | Oral clonidine to control hypertension after head injury. ( Asada, A; Kariya, N; Nishi, S; Shindoh, M; Yukioka, H, 1999) |
| " With the exception of one subject, all pre-eclamptics were taking clonidine (a known suppressant of rapid eye movement-REM-sleep) for control of their hypertension." | 3.70 | Pre-eclampsia is associated with marked alterations in sleep architecture. ( Blyton, CM; Edwards, N; Kesby, GJ; Sullivan, CE; Wilcox, I, 2000) |
| " The authors present a 10-year-old boy chronically treated with lisinopril, an angiotensin converting enzyme inhibitor, to control hypertension who developed hypotension following the addition of tizanidine, an alpha-2 agonist, for the treatment of spasticity." | 3.70 | Hypotension following the initiation of tizanidine in a patient treated with an angiotensin converting enzyme inhibitor for chronic hypertension. ( Johnson, TR; Tobias, JD, 2000) |
| " Using radiotelemetry for monitoring cardiovascular parameters of spontaneously hypertensive rats treated with clonidine or moxonidine, we showed that clonidine, unlike moxonidine, resulted in rebound hypertension after drug withdrawal." | 3.69 | Mechanisms of cardiac cell damage due to catecholamines: significance of drugs regulating central sympathetic outflow. ( Dhalla, KS; Dhalla, NS; Rupp, H, 1994) |
| "Clonidine is an alpha-adrenergic agent that is used in the treatment of hypertension." | 3.69 | Clonidine-induced bradycardia. ( Blount, BW; Golusinski, LL, 1995) |
| " In order to investigate further whether the increased sensitivity to inhibition by nifedipine of the responses to noradrenaline of aortae from spontaneously hypertensive stroke-prone (SHRSP) rats is related to the development of the hypertension, we have compared the sensitivity to noradrenaline, potassium chloride (KCl) and nifedipine of aortae from SHRSP and control (Wistar-Kyoto) WKY rats of different age groups (young: 3-5 weeks, and adult: 13-16 weeks)." | 3.69 | The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age. ( Iwanov, V; Jiang, GC; Moulds, RF, 1995) |
| "In this paper we describe a typical case of tetanus and report our observations with the centrally acting alpha 2-adrenoreceptor agonist clonidine." | 3.69 | Autonomic disturbance in severe tetanus: failure of parenteral clonidine to control blood pressure. ( Brown, JL; Mathias, CJ; Sinding, H, 1994) |
| "In order to investigate the changes of endogenous opiate systems in hypertension and their possible role in the pathogenesis in hypertension, we measured plasma concentrations of beta-endorphin, leucine-enkephalin, neurotension, arginine vasopressin, plasma renin activity and angiotensin II by radioimmunoassay in 60 normal persons and 120 patients with essential hypertension." | 3.69 | Plasma levels of beta-endorphin, leucine enkephalin and arginine vasopressin in patients with essential hypertension and the effects of clonidine. ( Ding, H; Wang, C; Zhang, T; Zheng, X, 1995) |
| "To study potential cardiac alpha 1-adrenoceptor changes in the stage of established hypertension, [3H]prazosin binding characteristics and norepinephrine (NE) stimulated production of inositol phosphates in the ventricular tissue of spontaneously hypertensive rats (SHR) and age-matched Wistar-Kyoto control rats (WKY) were determined." | 3.68 | Alpha 1-adrenoceptor subtypes and inositol phosphates production in heart ventricles of spontaneously hypertensive rats. ( Badia, A; Gascón, S; Ivorra, D; Vila, E, 1993) |
| "To appreciate the role of some neuropeptides in the antihypertensive mechanism of clonidine, 17 patients with essential hypertension were given po clonidine 150 micrograms tid for 3 d." | 3.68 | [Possible involvement of atrial natriuretic factor and vasopressin in antihypertensive mechanism of clonidine in humans]. ( Chen, DG; He, B, 1993) |
| "Plasma concentrations of beta-endorphin (beta-EP), leucine enkephalin (LEK), arginine vasopressin (AVP), neurotensin (NT), renin activity (PRA) and angiotensin II (AT-II) were determined before and after the treatment with clonidine in 117 patients with essential hypertension." | 3.68 | [Changes in plasma neuropeptides before and after clonidine in patients with essential hypertension]. ( Zheng, X, 1993) |
| "In the present study, we evaluated the relationship between hypertension and the antinociceptive effect of clonidine in genetically hypertensive rats." | 3.68 | Dissociation of hypertension and enhanced clonidine-induced antinociception in spontaneously hypertensive rats. ( Lee, HK; Lin, JC; Tsao, WL; Wang, Y, 1993) |
| " All the patients had excessive pressor and tachycardia responses to the mental-arithmetic and cold pressor tests and marked hypersensitivity to clonidine." | 3.68 | The diagnosis and treatment of baroreflex failure. ( Biaggioni, I; Hollister, AS; Mosqueda-Garcia, R; Netterville, JL; Robertson, D; Robertson, RM, 1993) |
| "Seven-month-old, lean male SHHF/Mcc-cp rats, a model of spontaneous hypertension, progressive renal dysfunction, and congestive heart failure (CHF), were treated with either clonidine (CL) or enalapril (EN) or received no treatment (CON) for 20 weeks." | 3.68 | Effects of enalapril and clonidine on glomerular structure, function, and atrial natriuretic peptide receptors in SHHF/Mcc-cp rats. ( Hamlin, RL; Jenkins, JE; Jurin, RR; McCune, SA; Radin, MJ, 1992) |
| "In the present study it was investigated whether hypertension induced by dopamine or hypotension induced by clonidine could influence the relative blood distribution in a s." | 3.68 | Effects of clonidine-induced hypotension and dopamine-induced hypertension on blood flows in prostatic adenocarcinoma (Dunning R3327) and normal tissues. ( Damber, JE; Grankvist, K; Henriksson, R; Jonsson, O; Widmark, A, 1992) |
| "The specific binding of the agonist [corrected], [3H]clonidine, to neural membranes and clonidine-induced mydriasis were used to evaluate the density and sensitivity [corrected] of alpha 2-adrenoceptors in the brain of spontaneously hypertensive rats (SHR) and sex- and age-matched normotensive Wistar-Kyoto (WKY) rats." | 3.68 | Decreased density and sensitivity of alpha 2-adrenoceptors in the brain of spontaneously hypertensive rats. ( Barturen, F; García-Sevilla, JA; Miralles, A; Olmos, G, 1991) |
| "In ten patients (age: 47-59 yr) with moderately severe essential hypertension, the humoral and hemodynamic effects of a 4-day therapy with 2 x 75 micrograms clonidine, 2 x 20 mg nifedipine (slow-release), and their combination were investigated and compared with baseline values." | 3.68 | Interactions of clonidine and nifedipine in moderately severe hypertensive patients. ( Hüting, J; Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V, 1991) |
| "To determine whether alterations of left ventricular (LV) structure are associated with improved LV function under chronic clonidine monotherapy (300-450 g/day) of essential hypertension, 11 male patients (age range 47-61 years) were followed for 5." | 3.68 | Left ventricular muscle mass and diastolic function in patients with essential hypertension under long-term clonidine monotherapy. ( Bahavar, H; Hüting, J; Mitrovic, V; Schlepper, M; Thormann, J, 1991) |
| "We assessed the sensitivity and specificity of glucagon stimulation and clonidine suppression tests in the diagnosis of pheochromocytoma in 113 hypertensive patients, 39 with and 74 without the tumor." | 3.68 | Glucagon and clonidine testing in the diagnosis of pheochromocytoma. ( Goldstein, DS; Grossman, E; Hoffman, A; Keiser, HR, 1991) |
| "Authors assessed correlation between venous blood catecholamines and prostaglandins concentrations before and after inhibition of sympathetic activity by clonidine in patients with primary hypertension or pheochromocytoma." | 3.68 | [Correlations between catecholamines and prostaglandins in patients with primary arterial hypertension and pheochromocytoma in basic conditions and after administration of clonidine]. ( Bar-Andziak, E; Chojnowski, K; Feltynowski, T; Ignatowska-Switalska, H; Lazecki, D; Wocial, B, 1990) |
| "The decrease in arterial blood pressure in patients with essential arterial hypertension treated with clonidine is associated, in 88." | 3.68 | Effect of clonidine on serum inorganic phosphorus in patients with essential arterial hypertension. ( Uza, G, 1990) |
| " They investigated therefore in 15 patients with essential hypertension (EH) and in three patients with pheochromocytoma the urinary excretion of free noradrenaline (NA), adrenaline (A) and dopamine (DA), the plasma renin activity (PRA), the aldosterone concentration (PAC) and atrial natriuretic factor (ANF) in plasma, using radioimmunoanalysis, always before and 24 hours after clonidine administration (Haemiton retardR) by the oral route." | 3.68 | [The effect of clonidine on humoral factors in patients with arterial hypertension]. ( Dvoráková, J; Gregorová, I; Horký, K; Kopecká, J; Poliak, M, 1990) |
| "Beta-endorphin (B-Ep), ACTH plasma levels and cortisol serum levels have been evaluated by RIA, in 27 patients suffering from essential blood hypertension and in 20 healthy control subjects." | 3.68 | [Plasma levels of beta-endorphin and ACTH and serum levels of cortisol in different stages of arterial hypertension before and after clonidine therapy]. ( Barletta, C; Scavo, D, 1990) |
| " To find whether other angiotensin converting enzyme inhibitors yield similar results, we prospectively examined the effect of enalapril in five consecutive patients with idiopathic membranous nephropathy, elevated arterial pressure, and proteinuria and compared them to age-matched controls receiving clonidine." | 3.68 | The effects of enalapril on urinary protein excretion in patients with idiopathic membranous nephropathy. ( Bakris, GL; Sauter, ER, 1990) |
| "In patients with essential hypertension, the vasodilator response in the forearm circulation to postjunctional alpha 1-adrenoceptor blockade with prazosin is enhanced." | 3.67 | Sympathetic nervous system in essential hypertension and antihypertensive response to alpha 2-adrenoceptor stimulation. ( Amann, WF; Bolli, P; Bühler, FR; Erne, P; Kiowski, W, 1984) |
| " Furthermore, acute and chronic administrations of clonidine were used to determine a participation of the sympathetic nervous system in the maintenance of hypertension in these patients." | 3.67 | Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine. ( Campese, VM; Levitan, D; Massry, SG; Romoff, M, 1984) |
| " Since clonidine has actually been found to improve renal hemodynamics in patients with essential hypertension, we studied the effects of clonidine therapy in patients with renal transplant hypertension." | 3.67 | Effect of clonidine therapy on renal hemodynamics in renal transplant hypertension. ( Goldman, M; Graybill, A; Green, S; Johnson, M; Mackenzie, T; McClanahan, M; Muakkassa, W; Zawada, ET, 1984) |
| "In ten patients with essential hypertension, 6 weeks of treatment with a clonidine/diuretic combination (1 retard capsule/day, 75 micrograms or 150 micrograms clonidine, and 15 mg chlortalidon) was suddenly discontinued." | 3.67 | [Clonidine-diuretic combination in patients with essential hypertension. Modification of sympathetic activity and blood pressure as well as the reaction following sudden withdrawal]. ( Beckenbauer, UE; Planz, G, 1984) |
| " Thirty subjects with hypertension on hydrochlorothiazide (HCTZ) were randomized to TIAM or CLON." | 3.67 | Withdrawal phenomena in subjects with essential hypertension on clonidine or tiamenidine. ( Hamilton, BP; Hamilton, J; Kuzbida, G; Levinson, P; Mersey, JH; Pavlis, R, 1984) |
| "The comparative efficacy and safety of lofexidine and clonidine in patients with mild to moderate systemic hypertension were evaluated." | 3.67 | Comparative efficacy and safety of lofexidine and clonidine in mild to moderately severe systemic hypertension. ( Lopez, LM; Mehta, JL, 1984) |
| " The amniotic fluid norepinephrine concentration (mean +/- SD) in cases of hypertension treated with clonidine (0." | 3.67 | Amniotic fluid norepinephrine concentration as an indicator of fetal sympathetic nervous activity. Effect of pregnancy complications. ( Kauppila, A; Puolakka, J; Vuori, J, 1984) |
| "In 10 patients (aged 46 to 72 years) with essential hypertension (grade III to IV), the acute effects on the haemodynamics in the systemic and pulmonary circulation were analysed following intravenous administration of clonidine." | 3.67 | The haemodynamic effects of clonidine in patients with grade III to IV hypertension. ( Hallier, E; Kuschke, HJ; Mitrović, V, 1986) |
| "Left ventricular mass and function were evaluated by M-mode echocardiography in 10 patients with essential hypertension, before and after 16 weeks of treatment with clonidine." | 3.67 | Clonidine and left ventricular function in ten patients with essential hypertension. ( Velandia Arevalo, J, 1986) |
| "To investigate the possible release of beta-endorphins (beta EN) from tumors and to investigate their possible involvement in the hypotensive mechanism of clonidine (CLO) in pheochromocytoma (PHEO), as compared with essential hypertension (EH), we studied 12 patients with PHEO, 17 patients with uncomplicated stable EH (SEH), nine patients with borderline EH (BEH), and seven healthy volunteers (N)." | 3.67 | Plasma beta-endorphins and catecholamines before and after clonidine in essential hypertension and pheochromocytoma. ( Chodakowska, J; Chojnowski, K; Feltynowski, T; Januszewicz, W; Lazecki, D; Wocial, B, 1987) |
| " To further investigate the functional significance of increased sympathoadrenal activity in uremia, a subset of dialysis patients was studied during chronic clonidine therapy." | 3.67 | Increased plasma norepinephrine and sympathetic nervous activity in essential hypertensive and uremic humans: effects of clonidine. ( Izzo, JL; Kallay, MC; Larrabee, PS; Santarosa, RP; Smith, RJ, 1987) |
| "To study the role of medullary alpha-adrenoceptors in hypertension, we compared specific binding of [3H]prazosin and [3H]clonidine in different brain regions of spontaneously hypertensive rats (SHR), stroke-prone SHR (SHRSP), and normotensive Wistar-Kyoto rats (WKY)." | 3.67 | Decreased density of alpha 2-adrenoceptors in medulla oblongata of spontaneously hypertensive rats. ( Ashizawa, N; Hayashi, E; Nakayama, K; Tomita, T; Yamada, S, 1989) |
| " Ten patients with essential hypertension underwent non-invasive automatic 24-h blood pressure monitoring three times (baseline and after three and seven days from the application on the upper chest of a transdermal self-adhesive patch delivering clonidine)." | 3.67 | New indices in the evaluation of clonidine transdermal therapy of hypertension. ( Becucci, A; Cinelli, P; de Leonardis, V; de Scalzi, M; Lusini, C, 1989) |
| "Administration of captopril to animals with two-kidney, one clip, renovascular hypertension (RH) lowers the glomerular filtration rate (GFR) in the clipped kidney." | 3.67 | The captopril glomerular filtration rate renogram in renovascular hypertension. ( Frederickson, ED; Phillips, MI; Smith, TB; Wilcox, CS; Williams, CM; Wingo, CD, 1989) |
| "We studied the acute effect of oral captopril (25mg) and clonidine(300 micrograms) on blood pressure (BP) in patients with essential hypertension successively maintained on a low (LSD) and high (HSD) salt diet." | 3.67 | Salt sensitivity in human essential hypertension: effect of renin-angiotensin and sympathetic nervous system blockade. ( Andriollo, A; Dichtchekenian, V; Heimann, JC; Marcondes, M; Sequeira, DM, 1989) |
| "The effects of placebo, propranolol, and clonidine on blood pressure and blood pressure variability were examined in 14 subjects who had moderate essential hypertension." | 3.67 | Blood pressure and blood pressure variability following withdrawal of propranolol and clonidine. ( Lowenstein, J; Neusy, AJ, 1989) |
| "Sixteen of 22 elderly male patients (aged 60-74 years) who had previously taken only hydrochlorothiazide 50 mg completed a study evaluating the safety, efficacy, and tolerability of 12-20 weeks of transdermal clonidine (Catapres TTS) as monotherapy for mild hypertension." | 3.67 | Transdermal clonidine compared with hydrochlorothiazide as monotherapy in elderly hypertensive males. ( Goodfriend, TL; Schmidt, GR; Schuna, AA, 1989) |
| " On this basis, functional and therapeutical regimen of regression of cardiac hypertrophy (prazosin, clonidine, nifedipine) are analyzed in concentric as well as in excentric hypertrophy in patients with arterial hypertension." | 3.67 | [Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects]. ( Strauer, BE, 1985) |
| "In young men with mild essential hypertension and age-matched normotensive volunteers, plasma concentrations of the endogenous opioid beta-endorphin were determined hourly from 9:00 p." | 3.67 | Clonidine normalizes low plasma beta-endorphin concentration and blood pressure in young men with mild essential hypertension. ( Kraft, K; Stumpe, KO; Theobald, R, 1986) |
| "Arterial blood pressure and central hemodynamic changes were assessed in 44 patients with essential hypertension, uncontrollable by prazosin alone, after propranolol (anaprilin), celiprolol, clonidine (clofelin) or verapamil were added to the treatment schedule." | 3.67 | [Hemodynamic effect of a combination of prazosin with cardiac depressants in the treatment of hypertension]. ( Akopian, LM; Basem, AS; Ivleva, AIa; Krasnobaeva, GM; Moiseev, VS, 1988) |
| "Whether peripheral beta-endorphin contributes to the antihypertensive action of clonidine was examined by measuring plasma levels of beta-endorphin-like immunoreactivity (beta EpLI) after acute administration of clonidine in patients with essential hypertension." | 3.67 | Central alpha-activation by clonidine reduces plasma level of beta-endorphin in patients with essential hypertension. ( Kanayama, Y; Kawarabayashi, T; Kohno, M; Kotsugai, N; Murakawa, K; Sato, K; Takeda, T; Yasunari, K, 1985) |
| "The role of central pressor mechanisms in the maintenance of blood pressure in six hypertensive patients with angiographically proven unilateral renal artery stenosis was investigated by studying the haemodynamic and hormonal responses before and after central sympathetic blockade with clonidine." | 3.67 | Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis. ( Kooner, JS; Mathias, CJ; Peart, S, 1988) |
| "The effects of clonidine or relaxation therapy were determined in two separate groups of patients with primary hypertension." | 3.67 | Noradrenergic hyperactivity in primary hypertension; central and peripheral markers of both behavioral pathogenesis and efficacy of sympatholytic and relaxation therapy. ( Barndt, R; Davison, GC; DeQuattro, V; Kimura, S; Lee, DD; Sullivan, P, 1988) |
| ") on clonidine hypotension in 80 patients with essential hypertension revealed that two groups could be separated." | 3.67 | beta-Endorphin and essential hypertension: importance of the clonidine-naloxone interaction. ( Balás-Eltes, A; Farsang, C; Kapocsi, J; Kunos, G; Vajda, L; Varga, K, 1985) |
| "Moxonidine (4-chloro-N-(4, 5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine, BDF 5895) reduces blood pressure and heart rate in rats with genetic hypertension (SHR/Okamoto) and in rats with renovascular hypertension (Goldblatt 1 k/1 c)." | 3.67 | General pharmacology of the novel centrally acting antihypertensive agent moxonidine. ( Armah, BI; Hofferber, E; Stenzel, W, 1988) |
| "A clonidine suppression test and the measurement of the catecholamine (noradrenaline and adrenaline) concentration in 24-hour urine were undertaken on 13 patients with benign phaeochromocytoma (PCC), 30 patients with benign hypertension (BHT) and ten healthy, normotensive volunteers." | 3.67 | [Diagnostic significance of the clonidine suppression test in suspected pheochromocytoma]. ( Ivens, K; Schürmeyer, T; Stimpel, M; Volkmann, HP; von zur Mühlen, A; Wambach, G, 1988) |
| "We identified eight hypertensive patients who developed severe bradycardia during oral clonidine hydrochloride therapy." | 3.67 | Risk factors for severe bradycardia during oral clonidine therapy for hypertension. ( Byrd, BF; Collins, HW; Primm, RK, 1988) |
| "The effect of short-term diuretic treatment on the action of clonidine was evaluated in eight subjects with mild, uncomplicated hypertension." | 3.67 | Diuretic treatment alters clonidine suppression of plasma norepinephrine. ( Felton, K; Hui, TP; Krakoff, LR; Yeager, K, 1986) |
| "We have recently seen a case of non-insulin-dependent diabetes mellitus with hypertension in which chronic treatment with oral clonidine gave rise to elevation of blood glucose and decreased insulin secretion." | 3.67 | Effect of clonidine on insulin secretion: a case report. ( Higuchi, T; Masaki, Y; Miyai, Y; Ogino, Y; Okada, S; Ota, Z; Sato, K, 1986) |
| "We report evidence that sublingual clonidine may be effective in the treatment of hypertension in the patient unable to take oral medication." | 3.67 | Effectiveness of sublingual clonidine in patients unable to take oral medication. ( Delaney, RL; Gilkeson, GS, 1987) |
| "In conscious rats with normal arterial blood pressure or with spontaneous or DOC induced hypertension, effects of drugs increasing (cycloserine, ethanolamine-o-sulphate, piracetam, chlordesmethyldiazepam) or depressing (bicuculline, Ro 15-1788, PK 11195) GABAergic reactivity were evaluated on the arterial hypotension and sinus bradycardia induced by clonidine." | 3.67 | Participation of GABAergic mechanisms in the hypotensive and bradycardic effects of clonidine: experimental study in conscious normotensive and hypertensive rats. ( Cazzola, M; Filippelli, W; Marmo, E; Marrazzo, R; Rossi, F; Russo, S; Vacca, C, 1987) |
| "We have studied the efficacy of clonidine hydrochloride administered transdermally once a week for 9 to 15 weeks in 12 patients with mild to moderate hypertension." | 3.67 | The efficacy of a transdermal formulation of clonidine in mild to moderate hypertension and its effects on the arterial and venous vasculature of the forearm. ( Achimastos, A; Girerd, X; Levenson, J; Pithois-Merli, I; Simon, AC, 1987) |
| "Clonidine is a centrally acting antihypertensive agent used in the management of essential hypertension." | 3.67 | Reversal of clonidine toxicity by naloxone. ( Getzug, T; Murphy, W; Niemann, JT, 1986) |
| "Intravenous clonidine was used to treat systolic hypertension (systolic blood pressure greater than 160 mm Hg) in 15 patients with acute myocardial infarction and documented sympathetic overactivity (high plasma norepinephrine)." | 3.67 | Central inhibition of sympathetic overdrive by clonidine in acute myocardial infarction with systolic hypertension. Haemodynamic study. ( Bernard, R; Liebens, I; Renard, M; Waterschoot, P, 1986) |
| "The safety of oral clonidine substitution in 29 patients with confirmed localized allergic contact dermatitis due to transdermal clonidine treatment was evaluated." | 3.67 | Oral substitution in patients sensitized by transdermal clonidine treatment. ( Maibach, HI, 1987) |
| "Pharmacokinetics of clonidine were examined in ten women during pregnancy, in nine during nursing, and in the newborns of these women." | 3.67 | Pharmacokinetics of clonidine during pregnancy and nursing. ( Hartikainen-Sorri, AL; Heikkinen, JE; Koivisto, M, 1987) |
| "Eighty two hypertensive pregnant patients were treated with clonidine during the last trimester of pregnancy." | 3.67 | Clonidine in the treatment of hypertension during pregnancy. ( Kauppila, E; Punnonen, R; Tuimala, R, 1985) |
| "The effectiveness of transdermally administered clonidine in normalizing blood pressure in 22 adolescents with sustained diastolic hypertension was studied." | 3.67 | Transdermal clonidine in the treatment of adolescent hypertension. ( Falkner, B; Lowenthal, DT; Thanki, B, 1985) |
| "Twenty patients aged 60-74 years entered a study on the effect of transdermal clonidine (Catapres-TTS) as monotherapy for mild hypertension [diastolic blood pressure (DBP) 90-104 mmHg]." | 3.67 | Transdermal clonidine therapy in elderly mild hypertensives: effects on blood pressure, plasma norepinephrine and fasting plasma glucose. ( Kelley, S; Klein, C; Metz, S; Morton, N, 1985) |
| "The putative role of the central nervous system in the maintenance of elevated blood pressure in patients with essential hypertension (EH) and renal hypertension [unilateral renal parenchymal disease (RPD) and unilateral renal artery stenosis (RAS)] was studied by investigating the cardiovascular and hormonal effects of the predominantly centrally acting sympatholytic agent, clonidine." | 3.67 | Cardiovascular and hormonal effects of clonidine in patients with essential hypertension and renal hypertension. ( Mathias, CJ; Peart, S; Stone, FA; Wilkinson, AH, 1985) |
| "The antihypertensive effect of clonidine hydrochloride delivered at a constant rate for seven days by transdermal disks was evaluated in seven patients with essential hypertension." | 3.67 | Transdermal clonidine therapy in hypertensive patients. Effects on office and ambulatory recorded blood pressure values. ( Brunner, HR; Nussberger, J; Porchet, M; Schaller, MD; Waeber, B, 1985) |
| "To assess the contribution of sympathetic outflow to blood pressure in patients with essential hypertension, we measured blood pressure and plasma norepinephrine responses to clonidine, an antihypertensive agent that decreases central sympathetic outflow, in 44 patients and in 41 normotensive control subjects of similar age." | 3.67 | Clonidine suppression testing in essential hypertension. ( Goldstein, DS; Keiser, HR; Levinson, PD; Pitterman, A; Stull, R; Zimlichman, R, 1985) |
| "Chronic administration of clonidine in the drinking water of spontaneously hypertensive (SH) rats from 11 through 17 weeks of age prevented the further development of hypertension in this model." | 3.67 | Long term treatment with clonidine during the development of hypertension in spontaneously hypertensive rats. ( Buccafusco, JJ; Serra, M; Smith, LJ; Sussman, AM, 1985) |
| " Following her routine intravenous (IV) injection of solubilized pentazocine and tripelennamine tablets ("Ts and Blues"), the patient developed severe hypertension, a finding not characteristic of either drug alone or of the combination." | 3.67 | An acute hypertensive response after intravenous use of a new pentazocine formulation. ( Barrett, SM; Reinhart, S, 1985) |
| " Muzolimine benefited hypertension in patients with expansion of the extracellular space and it also strengthened the effect of clonidine or minoxidil." | 3.67 | Muzolimine in advanced chronic renal failure. ( Alfonso, L; Aprile, M; Corlianò, C; De Blasi, V; Mastrangelo, F; Montinaro, AM; Napoli, M; Rizzelli, S, 1985) |
| "To elucidate the role of the central gamma-aminobutyric acid (GABA) system in the maintenance of deoxycorticosterone (DOCA)NaCl hypertension, the responses of mean arterial pressure (MAP), plasma norepinephrine (NE), and epinephrine (EP) to intracerebroventricular (ICV) administration of muscimol, a GABA agonist, and the responses of MAP to bicuculline, a GABA antagonist, and to clonidine, an alpha 2-adrenoceptor agonist known to lower blood pressure by inhibiting sympathetic tone, were examined in conscious, unrestrained 4 week DOCA/NaCl hypertensive rats and age-matched uninephrectomized control rats." | 3.67 | Enhanced depressor effect of muscimol in the DOCA/NaCl hypertensive rat: evidence for altered GABAergic activity in brain. ( Dawson, R; Nagahama, S; Oparil, S, 1985) |
| "23 patients presenting with symptoms of pheochromocytoma were subjected to the clonidine suppression test." | 3.67 | Preliminary results with the clonidine suppression test in the diagnosis of pheochromocytoma. ( Beyer, J; Brandstetter, K; Krause, U, 1985) |
| "Abrupt withdrawal of the centrally-acting antihypertensive agent, clonidine, is associated with a high incidence of rebound hypertension and tachycardia, with symptoms of sympathetic overactivity and increased catecholamine excretion." | 3.67 | Regimen for the control of blood pressure and symptoms during clonidine withdrawal. ( Campbell, BC; Reid, JL, 1985) |
| "This report reviews the available evidence for and against the combined use of clonidine and prazosin in treating hypertension." | 3.67 | Interaction between clonidine and alpha blockers. ( Jounela, AJ; Kanniainen, E; Lilja, M, 1985) |
| "The present survey paper, concerning newer drugs used in the treatment of arterial hypertension, deals with the following types of agents: centrally acting drugs, such as clonidine nd alpha-methyl-DOPA; vasodilator drugs with a direct action on smooth muscle, such as minoxidil; diuretic agents, with special reference to the choice of a drug from the vast number of compounds; beta-sympatholytic drugs (beta blockers) and which drug to choose; prazosin, with special reference to its considerable theoretical interest; drugs that influence the renin-angiotensin system, such as saralasin (P 113), an angiotensin II-antagonist; and inhibitors of the converting enzyme, such as teprotide (SQ 20,881) and captopril (SQ 14,225)." | 3.66 | Modern concepts in the drug treatment of arterial hypertension. ( van Zwieten, PA, 1980) |
| "This report describes the treatment of a Viet Nam veteran with an α(2)-adrenergic agonist (clonidine) for hypertension which had an additional beneficial effect of allowing withdrawal in ten days from 20 mg of methadone a day with minimal withdrawal symptoms." | 3.66 | Simultaneous treatment of hypertension and opiate withdrawal using an alpha 2-adrenergic agonist. ( Bell, CC, 1983) |
| "The efficacy and safety of 20 mg of nifedipine as a single oral dose have been studied with respect to the use of the drug as an alternative treatment of hypertensive emergencies." | 3.66 | An oral calcium antagonist for treatment of hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC, 1982) |
| "The effect of standing and physical exercise and catecholamines and cyclic nucleotides in plasma was measured in 8 patients with essential hypertension under standardized conditions before and after prolonged treatment with clonidine." | 3.66 | Plasma cyclic nucleotides and plasma catecholamines before and after prolonged treatment with clonidine in hypertensive patients. ( Heding, L; Hökfelt, B; Malmquist, J; Manhem, P, 1981) |
| "Studies were undertaken to investigate the role of the CNS in withdrawal hypertension caused by abrupt cessation of long-term clonidine treatment." | 3.66 | Central alpha-adrenergic control of blood pressure. Effects of clonidine withdrawal. ( Augustine, SJ; Buckley, JP; Lokhandwala, MF; Tachikawa, S, 1983) |
| "The systemic, cardiovascular hemodynamic and biochemical interactions between clonidine and minoxidil were studied in ten patients with refractory and/or accelerated hypertension." | 3.66 | Cardiovascular hemodynamic interactions between clonidine and minoxidil in hypertensive patients. ( Angeli-Greaves, M; Hernandez-Pieretti, O; Morillo, J; Silva, H; Urbina-Quintana, A; Velasco, M, 1983) |
| "Fifteen patients with essential hypertension and ten with pheochromocytoma were studied to assess the effect of clonidine, a centrally acting antihypertensive agent, on the functional and biochemical indices of sympathetic function." | 3.66 | Effects of clonidine on sympathetic function. ( Bravo, EL, 1983) |
| "Clonidine was given to patients with essential hypertension, renovascular hypertension, and hypertension with parenchymal renal disease." | 3.66 | The use of centrally acting antihypertensive drugs in patients with renal disease. ( Morgan, T, 1983) |
| "To study the possible influence of sympathetic adrenergic tone on the blood-brain barrier function during acute hypertension in conscious unrestrained rats with indwelling catheters in the aorta and a jugular vein the blood pressure was increase by noradrenaline, 6-hydroxydopamine (6-OHDA) or baclofen." | 3.66 | Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats. ( Auer, LM; Johansson, BB, 1983) |
| "The antihypertensive effects and side-effects of a clonidine transdermal therapeutic system (clonidine-TTS) were examined over 10 weeks in 22 patients with essential hypertension." | 3.66 | Clonidine through the skin in the treatment of essential hypertension: is it practical? ( Baumgart, P; Boerlin, HJ; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W; Walger, P; Wehling, M, 1983) |
| "Clonidine was administered by intravenous infusion to 12 patients classified as having exaggerated arterial hypertension, their systolic (SAP), diastolic (DAP) and mean (MAP) arterial pressures were significantly reduced from the third min." | 3.66 | Acute hypotensive action of clonidine after intravenous infusion in hypertensive emergencies. ( Fragachán, F; Monsalve, P; Pérez, J; Pérez-Acuña, F; Sanabria, A; Tremarias, A, 1983) |
| "5 mg clonidine (clonidine-TTS) was investigated in 21 patients with essential hypertension over a period of 10 weeks." | 3.66 | [Clonidine transdermal therapeutic system in essential hypertension: effect and tolerance]. ( Baumgart, P; Boerlin, HJ; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W; Walger, P; Wehling, M, 1983) |
| "This study analysed the effects of both seven and 30 days of treatment with clonidine on heart rate, blood pressure (BP), plasma norepinephrine (NE) levels and dopamine-beta-hydroxylase (DBH) activity at rest and after standing in seven patients with essential hypertension." | 3.66 | Effect of clonidine on sympathetic nervous system activity in patients with essential hypertension. ( Chernow, B; Coleman, MD; Lake, CR; Zaloga, GP; Ziegler, MG, 1983) |
| "To determine whether the alpha-adrenergic antagonist phenoxybenzamine would alter cardiovascular or plasma catecholamine response to the alpha-adrenergic agonist clonidine, six patients with pheochromocytomas and eight with labile hypertension were studied." | 3.66 | Effect of phenoxybenzamine on cardiovascular and plasma catecholamine responses to clonidine. ( Gross, M; Sisson, J; Zweifler, A, 1983) |
| "Two studies of the responses to clonidine as the sole antihypertensive drug in the treatment of mild-to-moderate hypertension are reported." | 3.66 | Hormonal and hemodynamic effects of short- and long-term clonidine therapy in patients with mild-to-moderate hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1983) |
| "The effect of clonidine on the relationship between sympathetic nervous system activity and the state of sodium-volume balance was studied in 15 patients with essential hypertension and normal renal function (group 1) and in 14 patients with hypertension and mild to moderate renal failure (group 2)." | 3.66 | Effects of acute and chronic treatment with clonidine. ( Campese, VM; Massry, SG, 1983) |
| "In 20 patients with severe hypertension, rapid oral clonidine titration was employed for control of blood pressure, with 0." | 3.66 | Use of oral clonidine for rapid titration of blood pressure in severe hypertension. ( Oguagha, C; Porush, JG; Spitalewitz, S, 1983) |
| "1 The interaction between mianserin and centrally-acting antihypertensive drugs was evaluated in normal volunteers and in patients with essential hypertension receiving either clonidine or methyldopa." | 3.66 | Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs. ( Elliott, HL; Reid, JL; Whiting, B, 1983) |
| " Ventilatory support must be available if apnea occurs." | 3.66 | Clonidine poisoning. A complex problem. ( Artman, M; Boerth, RC, 1983) |
| "Ten patients with essential hypertension were treated orally with clonidine, and the dose was titrated until the diastolic pressure fell below 90 mm Hg or at least 10 mm Hg below baseline, or until a maximum dose of clonidine of 1." | 3.66 | Plasma clonidine levels in hypertension. ( Barr, J; Maronde, RF; Rho, J; Velasquez, MT, 1983) |
| "A patient with essential hypertension treated with clonidine developed accelerated acute clonidine withdrawal syndrome during coronary artery bypass surgery." | 3.66 | Accelerated acute clonidine withdrawal syndrome during coronary artery bypass surgery. A case report. ( O'Connor, DE, 1981) |
| "The hypotensive effect of nifedipine was studied in 9 patients with severe hypertension." | 3.66 | Management of severe hypertension with nifedipine in combination with clonidine or propranolol. ( Abe, K; Chiba, S; Haruyama, T; Imai, Y; Irokawa, N; Ito, T; Miura, Y; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1980) |
| "A simultaneous analysis of the interrelationships between mean blood pressure (MBP), plasma catecholamines, plasma renin activity (PRA) and aldosterone, exchangeable body sodium, and blood volume was carried out before and after acute and chronic administration of clonidine in 15 patients with essential hypertension, in order to further elucidate the mechanism(s) of action of this drug." | 3.66 | Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension. ( Campese, VM; Massry, SG; Romoff, M; Telfer, N; Weidmann, P, 1980) |
| "Eight patients with essential hypertension, WHO grade I-III, were studied under standardized conditions in a metabolic ward, before and after 8-20 weeks of treatment with clonidine in a maintenance dose of 300-600 micrograms/24 h." | 3.66 | Prolonged clonidine treatment: catecholamines, renin activity and aldosterone following exercise in hypertensives. ( Hökfelt, B; Manhem, P, 1981) |
| "Eight patients with essential hypertension were treated with 50 microgram oral clonidine four times daily for 4 wk followed by 75 to 150 microgram four times daily for another 4 to 16 wk." | 3.66 | Plasma clonidine in relation to blood pressure, catecholamines, and renin activity during long-term treatment of hypertension. ( Hökfelt, B; Manhem, P; Paalzow, L, 1982) |
| "1 We have compared, in patients with severe hypertension, the administration of intravenous labetalol by single rapid injection, by repeated bolus injections, and by incremental infusion." | 3.66 | Intravenous labetalol in the treatment of severe hypertension. ( Brown, JJ; Cumming, AM; Lever, AF; Robertson, JI, 1982) |
| "We examined the hemodynamic interaction between clonidine, a centrally acting antiadrenergic drug, and minoxidil, a potent antihypertensive vasodilator in 10 inpatients with refractory or accelerated hypertension or both." | 3.66 | Systemic and cardiac hemodynamic interactions between clonidine and minoxidil. ( Aliendres, R; Andrews-Figueroa, P; Hernańdez-Pieretti, O; Morillo, J; Ramiŕez, A; Urbina-Quintana, A; Velasco, M, 1981) |
| " In four patients, whose hypertension was not controlled (supine blood pressure greater than 150--90 mmHg) by addition of 5 mg/day of prazosin to previous treatment (diuretics and beta-blockers), clonidine (150--450 microgram/day) led to control of hypertension in three cases." | 3.66 | Lack of antagonism in the antihypertensive effects of clonidine and prazosin in man. ( Andréjak, M; Coevoet, B; Comoy, E; De Fremont, JF; Fievet, P; Fournier, A; Makdassi, R, 1981) |
| "A case of rebound hypertension under anaesthesia, following withdrawal of clonidine, is described and methods of treatment outlined." | 3.66 | Rebound hypertension during anaesthesia. ( Stevens, JE, 1980) |
| "Hemodynamic and humoral effects of lofexidine were assessed in 11 patients with essential hypertension after a total of 1." | 3.66 | Early hemodynamic and humoral effects of lofexidine. ( Bravo, EL; Fouad, FM; Tarazi, RC; Vidt, DG; Williams, H, 1981) |
| "4 patients with hypertensive crisis (glomerulonephritis [n = 2], phaeochromocytoma [n = 1], reno-vascular hypertension [n = 1] combined with encephalopathy, showed a normalisation of blood-pressure up to 18 days during angiotensin-II-blockade with saralasin." | 3.66 | [Saralasin in resistant hypertensive crisis (author's transl)]. ( Heidland, A; Röckel, A, 1979) |
| "Intra-cisternal clonidine (3 microgram/kg) reduced hypertension and cardiac acceleration after defrenation in dogs, but did not act in intra-venous infusion (10 microgram/kg)." | 3.66 | [Effect of clonidine on three types of experimental hypertension and on plasma renin activity in dogs]. ( Moatti, JP; Montastruc, JL; Montastruc, P, 1978) |
| " Clonidine (6 mg of base/l of water) was given as drinking fluid to normotensive rats or rats with established or early hypertension." | 3.66 | Effect of chronic clonidine treatment and its abrupt cessation on mean blood pressure of rats with a normal or an elevated blood pressure. ( Atkinson, J; Boillat, N; Kirchertz, EJ; Pera-Bally, R; Peters-Haefeli, L, 1979) |
| "11 coronary patients, 8 with mild hypertension, were treated with clonidine, at a dose of 75 micrograms b." | 3.66 | The therapeutic value of clonidine in patients with coronary heart disease. ( Amrein, R; Chu, D; Cocco, G; Haeusler, G; Padovan, GC; Strozzi, C, 1979) |
| "A study of the use of clonidine in the treatment of patients with hypertension, both in hospital and in the community, during a period of 6 years is reported." | 3.66 | Clonidine in hypertension: a 6-year review. ( Keston, M; Lawson, AA, 1979) |
| "Diazoxide, clonidine and labetalol, administered intravenously in fixed doses, were used to treat 30 episodes of severe hypertension in 27 patients." | 3.66 | Comparison of labetalol, clonidine and diazoxide intravenously administered in severe hypertension. ( Kincaid-Smith, P; Thomas, GW; Whitworth, JA; Yeung, CK, 1979) |
| " The mother took clonidine during pregnancy." | 3.66 | Roberts's syndrome and clonidine. ( Beshara, D; Levy, JM; Stoll, C, 1979) |
| "Nineteen patients with severe essential hypertension or hypertension due to renal parenchymal disease were treated with intravenous clonidine." | 3.66 | Evaluation of intravenous clonidine in hypertensive emergencies. ( Niarchos, AP, 1978) |
| "Rebound hypertension occurred in two patients upon clonidine withdrawal." | 3.66 | Hypertension after clonidine withdrawal. ( Batson, HM; deCarvalho, JG; Frohlich, ED; Husserl, FE, 1978) |
| "In order to determine the efficacy and safety of oral clonidine loading to control hypertension rapidly, 15 patients received 0." | 3.66 | Oral clonidine loading for rapid control of hypertension. ( Cohen, IM; Katz, MA, 1978) |
| " To determine if the enhanced sympathetic response to PH stimulation seen in adult SHR is an intrinsic difference rather than secondary to sustained hypertension, we maintained SHR normotensive from four weeks of age with antihypertensive drug therapy (clonidine or hydralazine)." | 3.66 | Effect of hypothalamic stimulation in spontaneously hypertensive and Wistar-Kyoto rats. ( Juskevich, JC; Robinson, DS; Whitehorn, D, 1978) |
| " In seventeen patients with untreated essential hypertension the sodium and water contents of leucocytes were significantly increased, whereas the rate constant for ouabain-sensitive sodium efflux was significantly reduced." | 3.65 | Abnormal sodium transport in leucocytes from patients with essential hypertension and the effect of treatment. ( Edmondson, RP; Hilton, PJ; Jones, NF; Thomas, RD, 1975) |
| "In various kinds of hypertension clonidine induced a decrease in urinary catecholamines, plasma renin activity and urinary aldosterone, concommitant with a fall in blood pressure and pulse rate in both short term and chronic studies." | 3.65 | The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients. ( Hansson, BG; Hedeland, H; Hökfelt, B, 1975) |
| " Clearances were slightly improved by clonidine, claimed to be useful in hypertension associated with chronic renal failure." | 3.65 | Study of renal functions by repeated constant infusion of radiotracers before and after initiation of therapy in hypertension or in diabetes mellitus. ( Mirouze, J; Monnier, L; Olivier, C, 1975) |
| "Clonidine failed to reduce the blood pressures of two patients with essential hypertension." | 3.65 | Apparent resistance to hypotensive effect of clonidine. ( Dargie, HJ; Davies, DS; Dollery, CT; Reid, JL; Wing, LM, 1977) |
| "In 12 hospitalized patients with hypertension, clonidine 3 times a day led to better control of blood pressure than did the same total dose administered once daily." | 3.65 | Efficacy and acceptability of different dosage schedules of clonidine. ( Jain, AK; McMahon, FG; Ryan, JR; Vargas, R, 1977) |
| "Chronic hypertension has been produced in mongrel dogs by the long-term oral administration of metyrapone (100 mg/kg per day)." | 3.65 | Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs. ( Bravo, EL; Dustan, HP; Tarazi, RC, 1977) |
| "Systolic time intervals, including preejection period (PEP) and left ventricular ejection time (LVET), were studied in patients with permanent essential hypertension before and after intra-venous administration of propranolol 0." | 3.65 | Effect of certain antiadrenergic agents on systolic time intervals in essential hypertension. ( Aboras, NE; Lelguen, CE; Milliez, PM; Roland, EQ; Safar, ME; Weiss, YA, 1977) |
| " The cardio-renal haemodynamic and endocrine effects of the anti-hypertensive agents 2-(2,6-dichlorophenylamine)-2-imidazoline hydrochloride (clonidine, St 155) and 2-(5-fluor-o-toluidine)-2-imidazoline hydrochloride (St 600) were investigated in twelve patients with essential hypertension." | 3.65 | Haemodynamic and endocrine changes during anti-hypertensive treatment with clonidine and its derivative St 600. ( Birkenhäger, WH; de Leeuw, PW; Kho, TL; Wester, A; Zaal, GA, 1976) |
| " Clonidine hydrochloride, an antihypertensive drug believed to directly stimulate brain norepinephrine receptors, was administered to a group of patients with relatively mild Parkinson disease and coexisting essential hypertension and to three patients with Parkinson disease manifesting the "on-off" response to levodopa." | 3.65 | Clonidine in Parkinson disease. ( Marsden, CD; Parkes, JD; Tarsy, D, 1975) |
| "Clonidine, 225 mug a day, has been given orally for 3 months to 15 patients with essential hypertension." | 3.65 | Plasma renin activity, blood pressure and sodium excretion during treatment with clonidine. ( Fyhrquist, F; Huuskonen, M; Kurppa, K, 1975) |
| "The effects of the antihypertensive imidazoline compounds 2-(5 fluor-0-toluidine)-2-imidazoline hydrochloride (ST 600) and 2-(2, 6 dichlorophenylamine)-2-imidazoline hydrochloride (ST 155, clonidine, Catapres) on intra-arterial pressure, cardiac output, stroke volume, heart rate, total peripheral resistance, renal blood flow, glomerular filtration rate, renal vascular resistance, plasma volume, plasma renin and aldosterone concentration were studied in five patients with essential hypertension." | 3.65 | Comparison between the effects of ST 600 and clonidine. ( Birkenhäger, WH; Kho, TL; Schalekamp, MA; Wester, A; Zaal, GA, 1975) |
| " In contradistinction, clonidine caused a dose-related hypotension in conscious unrestrained rats subjected to sodium depletion via furosemide." | 3.65 | Hypotensive effect of clonidine during sodium depletion in the rat. ( Pals, DT, 1975) |
| "Nicardipine and clonidine were compared with placebo in a double-blind, randomized, three-way cross-over controlled study after a 2-week placebo run-in period." | 2.70 | Effects of nicardipine and clonidine on cognitive functions and electroencephalography in hypertensive patients. ( Allain, H; Bentué-Ferrer, D; Breton, S; Cimarosti, I; Denolle, T; Gandon, JM; Merienne, M; Ouatara, B; Sassano, P, 2002) |
| "Concern based on the reported short-term adverse effects of antihypertensive agents on plasma lipid and lipoprotein profiles (PLPPs) has complicated the therapy for hypertension." | 2.69 | Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. ( Cushman, WC; Freis, ED; Lakshman, MR; Materson, BJ; Reda, DJ, 1999) |
| "Clonidine was associated with a significant (P < 0." | 2.69 | Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischaemia and recovery. ( Buckland, MR; Bujor, MA; Davis, BB; Esmore, DS; Hall, J; Holdgaard, HO; Hunt, JO; McRae, R; Moloney, J; Morgan, DJ; Myles, PS, 1999) |
| "Sevoflurane was titrated against a BIS held between 40 and 50." | 2.69 | Influence of intravenous clonidine pretreatment on anesthetic requirements during bispectral EEG-guided sevoflurane anesthesia. ( Buyse, L; De Deyne, C; De Jongh, R; Deghislage, J; Heylen, R; Rolly, G; Struys, M; Van der Laenen, M, 2000) |
| "Our study suggests that hypertensive NIDDM patients, particularly patients with nephropathy, frequently suffer from impaired or abolished autoregulation of GFR." | 2.68 | Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients. ( Christensen, PK; Hansen, HP; Parving, HH, 1997) |
| "Atenolol was successful by this definition in 51 percent of the patients, clonidine in 50 percent, hydrochlorothiazide in 46 percent, captopril in 42 percent, and prazosin in 42 percent; all these agents were superior to placebo (success rate, 25 percent)." | 2.67 | Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. ( Cushman, WC; Freis, ED; Fye, C; Gottdiener, J; Hamburger, RJ; Kochar, MS; Lakshman, R; Massie, BM; Materson, BJ; Reda, DJ, 1993) |
| " Clonidine-related side effects are still evident, but the overall tolerance profile for this reduced dosage of the drug appears to be favorable." | 2.67 | Low-dose clonidine administration in the treatment of mild or moderate essential hypertension: results from a double-blind placebo-controlled study (Clobass). The Clobass Study Group. ( , 1990) |
| " Twenty-one patients with concentric LVH (thickness of interventricular septum, IVS, and left posterior wall, LPW, above 11 mm) were given a 2D and M-mode echocardiogram before (pre) and 12 and 24 weeks, respectively, after therapy was initiated (mean oral cl dosage 150 micrograms; nf, 30 mg/day)." | 2.66 | Effects of clonidine and nifedipine on left ventricular hypertrophy and muscle mass in hypertensive patients. ( Brückner, S; Kleine, P; Meissner, E; von Bruchhausen, V, 1987) |
| "Nitrendipine is a new calcium antagonist of the 1,4-dihydropyridine group with strong vasodilating properties." | 2.66 | Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate. ( Grosser, KD; Späh, F, 1988) |
| " Although some patients remained normotensive after discontinuation of step II drugs, a greater proportion returned to elevated BP than when step II dosage was unchanged." | 2.66 | Effects of reduction in drugs or dosage after long-term control of systemic hypertension. ( Borreson, RE; Fisher, SG; Freis, ED; Hamburger, R; Mezey, KC; Mukherji, B; Neal, WW; Perry, HM; Taguchi, JT; Thomas, JR, 1989) |
| "Foridon is not indicated for the treatment of renal hypertension." | 2.66 | [Use of foridon in the treatment of arterial hypertension and hypertension of the lesser circulation]. ( Demidiuk, VT; Mikunis, RI; Monastyrskiĭ, IuI; Pshelutskiĭ, FF; Serkova, VK, 1988) |
| " Evaluation in approximately 2000 patients with mild to moderate hypertension has shown that the bioavailability of transdermal clonidine is comparable to that of oral clonidine and that equivalent blood pressure reductions are achieved." | 2.66 | Efficacy of clonidine as transdermal therapeutic system: the international clinical trial experience. ( Bies, C; Cristal, N; Fagan, T; Lowenthal, DT; Paran, E; Saris, S; Sharif, K, 1986) |
| " alpha-Methyldopa and clonidine produced the same hypotensive response at 6 and 8 h after dosing with a similar fall in plasma noradrenaline levels at these times." | 2.66 | The plasma noradrenaline and growth hormone response to alpha-methyldopa and clonidine in hypertensive subjects. ( Adams, EF; Brown, MJ; Dollery, CT; Struthers, AD, 1985) |
| " dosing schedules of clonidine on blood pressure, side-effects and plasma concentration of clonidine were studied in a randomized cross-over study." | 2.65 | Clonidine twice daily in hypertension. Effects of two dosage regimens on blood pressure, side-effects and plasma clonidine concentrations. ( Huikuri, H; Jounela, AJ; Juustila, HJ; Lilja, M; Paalzow, G, 1983) |
| "Nifedipine is a simple, effective, and safe alternative drug for managing hypertensive emergencies, especially when continuous monitoring of the patient cannot be guaranteed." | 2.65 | Nifedipine in hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC; Lang, C; Müller, J; Radü, EW, 1983) |
| "1 Tiamenidine (Hoe 440) is an imidazoline with blood pressure lowering properties." | 2.65 | Changes in blood pressure, plasma catecholamines and plasma renin activity during and after treatment with tiamenidine and clonidine. ( Hansson, BG; Hökfelt, B, 1981) |
| "Prazosin was better tolerated, with side effects tending to diminish with time." | 2.64 | Prazosin and clonidine for moderately severe hypertension. ( Hammond, JJ; Kirkendall, WM; Overturf, ML; Thomas, JC; Zama, A, 1978) |
| " The dosage was kept unchanged or increased according to the antihypertensive response." | 2.64 | The use of clonidine and practolol in the treatment of hypertension. ( Ala-Laurila, P; Pitkäjärvi, T; Ruosteenoja, R; Torsti, P, 1976) |
| " Small initial dosage and cautious incrementation is needed to avoid patient resistance from side-effects, principally fatigue, dry mouth and constipation, but once satisfactory control is achieved maintenance therapy is relatively trouble free." | 2.64 | A clinical trial of clonidine (Catapres) in private practice. ( Bostock, MI, 1975) |
| "Both hypertension and orthostatic hypotension (OH) are strongly age-associated and are common management problems in older people." | 2.55 | Orthostatic hypotension: pathophysiology, assessment, treatment and the paradox of supine hypertension. ( Anpalahan, M; Chisholm, P, 2017) |
| "Hypertension is a major risk factor for cardiovascular disease, but control of hypertension remains inadequate, often because of poor patient adherence to prescribed medical regimens that are viewed as poorly tolerated and expensive." | 2.47 | Older blood pressure medications-do they still have a place? ( Black, HR; Slim, HB; Thompson, PD, 2011) |
| "While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances." | 2.41 | The diagnosis and management of hypertensive crises. ( Marik, PE; Varon, J, 2000) |
| " Both drugs, when applied in a once-daily dosage schedule, appear to control hypertension in most patients." | 2.40 | Central I1-imidazoline receptors as targets of centrally acting antihypertensive drugs. Clinical pharmacology of moxonidine and rilmenidine. ( Peters, SL; Van Zwieten, PA, 1999) |
| " More controlled trials with less aggressive dosing regimens and placebo controls need to be performed to assess the most appropriate treatment for HUs with the fewest adverse effects." | 2.39 | Oral antihypertensives for hypertensive urgencies. ( Gales, MA, 1994) |
| " The principal disadvantages of this class of medications are an overlap between the therapeutic dosage and that producing sedation and dry mouth and the potential to cause the discontinuation syndrome and sexual dysfunction." | 2.38 | Use of centrally acting sympatholytic agents in the management of hypertension. ( Epstein, M; Oster, JR, 1991) |
| "A case or primary hyperaldosteronism due to unilateral macronodular adrenal hyperplasia is presented." | 2.38 | [Primary hyperaldosteronism caused by unilateral macronodular hyperplasia]. ( Bernardin, M; Chapuis, Y; Dorey, F; Fouchard, J; Louvel, A; Luton, JP, 1989) |
| "Clonidine is an alpha-adrenergic agonist." | 2.38 | Fetal effects of maternally administered clonidine and angiotensin-converting enzyme inhibitors. ( Boutroy, MJ, 1989) |
| "Hypertension in pregnancy has implications for both maternal and fetal welfare." | 2.37 | Hypertension in pregnancy. Pathophysiology and management. ( Lubbe, WF, 1984) |
| "Clonidine is a centrally acting alpha 2-agonist whose clinical use has often been limited by the dose dependent side effects of dry mouth and sedation, and the belief that it should be given three times per day." | 2.37 | Comparison of pharmacokinetics and pharmacodynamics of adrenoceptor agonists and antagonists as antihypertensive agents. ( Anavekar, SN; Conway, EL; Drummer, OH; Howes, LG; Jarrott, B; Louis, WJ; McNeil, JJ; Workman, B, 1987) |
| "Although drug treatment of hypertension is associated with improved survival and decreased vascular complications, drug compliance is a major problem in the control of hypertension." | 2.36 | Antihypertensive pharmacology. ( Freed, CR; Gerber, JG; Nies, AS, 1980) |
| "Severe hypertension is more likely to occur in the predisposed, and malignant hypertension has been reported." | 2.35 | Drug-induced hypertension: pathogenesis and management. ( Stokes, GS, 1976) |
| "Acute treatment of severe hypertension produced unpredictable and potentially dangerous responses in SBP." | 1.51 | Outcomes of minority patients with very severe hypertension (>220/>120 mmHg). ( Afshartous, D; Arciniegas, R; Bernstein, J; DeGraff, S; Materson, BJ; Preston, RA, 2019) |
| "We aimed to determine if naloxone administration reversed the effects of clonidine or caused any adverse effects." | 1.48 | Naloxone reversal of clonidine toxicity: dose, dose, dose. ( Loden, JK; Seger, DL, 2018) |
| "Clonidine is an imidazoline derivative antihypertensive medication that is also used as adjunctive therapy for neuropathic pain disorders via topical administration." | 1.40 | Dermal exposure to a compounded pain cream resulting in severely elevated clonidine concentration. ( Fantz, CR; Gooden, CE; Morgan, BW; Pomerleau, AC, 2014) |
| "Clonidine treatment significantly enhanced the total antioxidant status (TAS) (P < 0." | 1.39 | Effect of Clonidine (an antihypertensive drug) treatment on oxidative stress markers in the heart of spontaneously hypertensive rats. ( Govindasamy, C; Mustapha, Z; Nik Yusoff, NS; Sirajudeen, KN, 2013) |
| "Current pharmacotherapies for PTSD manage only a subset of these symptoms and typically have adverse side effects which limit their overall effectiveness." | 1.39 | Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD. ( Diamond, DM; Fleshner, M; Zoladz, PR, 2013) |
| "Age and hypertension are two major determinants of arterial stiffness, as well as endothelial dysfunction." | 1.38 | Chronic reduction of nitric oxide level in adult spontaneously hypertensive rats induces aortic stiffness similar to old spontaneously hypertensive rats. ( Clavreul, N; Isabelle, M; Ragonnet, C; Sansilvestri-Morel, P; Simonet, S; Vayssettes-Courchay, C; Verbeuren, TJ, 2012) |
| "Nitroglycerine was the most commonly used antihypertensive treatment overall (40% of patients), followed by urapidil (21%), clonidine (16%) and furosemide (8%)." | 1.37 | Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT). ( Anderson, FA; de La Garanderie, DP; Emery, L; Gore, JM; Rushton-Smith, S; Vincent, JL; Vuylsteke, A; Wyman, A, 2011) |
| "Clonidine treatment also reduced arterial pressure and increased functional capillary density in the skin and skeletal muscle of WKY." | 1.36 | Microvascular effects of centrally acting antihypertensive drugs in spontaneously hypertensive rats. ( Bousquet, P; Lessa, MA; Nascimento, AR; Sabino, B; Tibiriçá, E, 2010) |
| "Clonidine treatment significantly reduced noradrenaline and adrenaline plasma levels in spontaneously hypertensive rats and Wistar Kyoto rats." | 1.35 | Effect of clonidine on tyrosine hydroxylase activity in the adrenal medulla and brain of spontaneously hypertensive rats. ( Afonso, J; Moura, E; Serrão, MP; Vieira-Coelho, MA, 2009) |
| "We performed a prospective case series to seek dosage or clinical parameters to better identify patients who need direct medical evaluation." | 1.33 | Toxic clonidine ingestion in children. ( Anderson, DL; Colvin, JM; Johnson, PB; Klein-Schwartz, W; Spiller, HA; Villalobos, D, 2005) |
| " Similar responses were observed after oral dosing and in lean littermates." | 1.32 | The role of I(1)-imidazoline and alpha(2)-adrenergic receptors in the modulation of glucose metabolism in the spontaneously hypertensive obese rat model of metabolic syndrome X. ( Ernsberger, P; Velliquette, RA, 2003) |
| "Only clonidine treatment totally prevented the development of insulin resistance, and high-dose aspirin, known to prevent insulin resistance by inhibition of the activity of IkappaB kinase-beta, decreased the degree of insulin resistance by almost 70%." | 1.32 | Hypertension and insulin resistance are not directly related in obese dogs. ( Gokee, A; Rocchini, AP; Yang, JQ, 2004) |
| "Baroreflex failure after chemodectoma resection We present a case of baroreflex failure secondary to a unilateral injury of the glossopharyngeal nerve." | 1.32 | [Baroreflex failure after chemodectoma resection]. ( Allue, I; Boyero, S; Fernández, C; Gómez Esteban, JC; Lezcano, E; Pérez, T; Sagasta, A; Velasco, F; Zarranz, JJ, 2004) |
| "Mirtazapine is a new antidepressant with a tetracyclic chemical structure that is not related to selective serotonin reuptake inhibitors, tricyclic antidepressants, or monoamine oxidase inhibitors." | 1.31 | Hypertensive urgency induced by an interaction of mirtazapine and clonidine. ( Abo-Zena, RA; Bobek, MB; Dweik, RA, 2000) |
| "Systemic hypertension is common in individuals with non-insulin-dependent diabetes (NIDD) and, in this population, markedly increases the risk for cardiovascular complications." | 1.31 | NaCl-induced hypertensive rat model of non-insulin-dependent diabetes: role of sympathetic modulation. ( Mozaffari, MS; Patel, C; Schaffer, SW; Warren, BK, 2000) |
| "Headache was the presenting and most prominent complaint, with daily episodes of short-lasting, intermittent, and paroxysmal attacks." | 1.31 | Recurrent short-lasting headache associated with paroxysmal hypertension: a clonidine-responsive syndrome. ( Dodick, DW, 2000) |
| " The results obtained show that Adalat in dosage 60 mg daily during 7 days is most effective in cases with concomitant border-line hypertension." | 1.30 | [Premedication with different groups of hypotensive drugs in preparation of patients with concomitant arterial hypertension to planned surgical treatment]. ( Eliutin, DV; Mil'tsyn, AS; Sadchikov, DV, 1998) |
| "Moxonidine was more effective by this route than after the injection into the lateral ventricle." | 1.30 | Effect of moxonidine on blood pressure and sympathetic tone in conscious spontaneously hypertensive rats. ( Chung, O; Culman, J; Haass, M; Nurminen, ML; Unger, T, 1998) |
| "Clonidine overdose is a potentially serious condition, often requiring intensive care management." | 1.30 | Clonidine overdose in childhood: implications of increased prescribing. ( Hanson, RM; Hutchins, P; Kappagoda, C; Schell, DN, 1998) |
| "The clonidine test was very useful, particularly for cases where biochemical results were discrepant." | 1.30 | [A comparative study of 9 cases of adrenal pheochromocytoma and 11 cases of extra-adrenal pheochromocytoma]. ( Aliaga Martínez, L; Fernández-Torres, C; Hidalgo Tenorio, C; López de la Torre Casares, M; Mediavilla García, JD; Muros de Fuentes, MA; Peran Mesa, F, 1999) |
| "The clonidine test was found to be safe and should be preferred to the glucagon test which has to be restricted to very selected patients." | 1.30 | Pheochromocytoma in Italy: a multicentric retrospective study. ( Cilotti, A; Conti, A; Ianni, L; Mannelli, M, 1999) |
| "Clonidine was given i." | 1.30 | Systemic injection with DSP-4 decreases the clonidine hypotension in bicuculline-treated rats. ( Czyźewska-Szafran, H; Gozlinska, B, 1999) |
| "Moxonidine is a centrally acting antihypertensive with a selective action on I1-imidazoline receptors in RVLM." | 1.29 | Selective antihypertensive action of moxonidine is mediated mainly by I1-imidazoline receptors in the rostral ventrolateral medulla. ( Dreshaj, I; Ernsberger, P; Haxhiu, MA; Schäfer, SG, 1994) |
| "Regression of left ventricular hypertrophy (LVH) were remarkable in Groups A and C, but not to the extent in that of WKY." | 1.29 | Sympatholytic effect of captopril in regression of cardiovascular remodeling in spontaneously hypertensive rats. ( Chen, DG; Chen, HJ; Wang, HJ; Xie, LD; Zhang, S, 1994) |
| "Felodipine was equally effective at both time points." | 1.29 | Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats. ( Janssen, BJ; Oosting, J; Struyker-Boudier, HA; Tyssen, CM, 1993) |
| "Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes." | 1.29 | Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Hypertension was associated with enhanced pressor response, whereas the diabetic state counteracted this effect." | 1.29 | Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "A polydrug abuser had been prescribed clonidine for hypertonia but ingested it for its sedative properties and for euphoria over a period of 6 years." | 1.29 | [Clonidine--potential dependence risk in psychiatric patients?]. ( Agelink, MW; Dammers, S; Zeit, T, 1996) |
| "The pharmacokinetic characteristics of a slow-release formulation of clonidine (150 micrograms) were compared with those of a conventional formulation (75 micrograms) after acute and chronic (2 week) administration to 12 hypertensive subjects." | 1.28 | Pharmacokinetic comparison of a slow-release clonidine with a conventional formulation after acute and chronic administration in hypertensives. ( Anavekar, SN; Conway, EL; Howes, LG; Louis, WJ, 1992) |
| " Chronic administration of clonidine, 10 micrograms." | 1.28 | Effect of clonidine on blood pressure and GABAergic mechanisms in spontaneously hypertensive rats. ( Czyzewska-Szafran, H; Jastrzebski, Z; Remiszewska, M; Wutkiewicz, M, 1991) |
| "Treatment with clonidine reduced both circadian variability of BP and HR and the awakening increase." | 1.28 | Modification of circadian blood pressure and heart rate variability by five different antihypertensive agents in spontaneously hypertensive rats. ( Janssen, BJ; Struyker-Boudier, HA; Tyssen, CM, 1991) |
| " Chronic administration of spironolactone prevented the development of hypertension but failed to prevent other adaptive physiological changes characteristically occurring during exposure to cold and seen in the cold-treated control rats." | 1.28 | Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991) |
| "Rilmenidine is an oxazoline analogue that has antihypertensive properties that resemble those of clonidine." | 1.28 | Regional hemodynamic effects of rilmenidine and clonidine in the conscious spontaneously hypertensive rat. ( Smits, JF; Struyker-Boudier, HA, 1991) |
| " Indeed, we observed a strong correlation between patient compliance and the administration of agents with longer dosing intervals and improved side effects profiles." | 1.28 | Improving compliance in an inner-city hypertensive patient population. ( Batts, JM; Branche, GC; Dowdy, VM; Field, LS; Francis, CK, 1991) |
| " These variables were: age, gender, prior utilization of medical services, regimen complexity, and dosage formulation." | 1.28 | Utility of a transdermal delivery system for antihypertensive therapy. Part 1. ( Chin, A; Gill, MA; Okamoto, MP; Sclar, DA; Skaer, TL, 1991) |
| " It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency." | 1.28 | Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990) |
| "Moderate pyridoxine deficiency in adult male Sprague-Dawley rats results in significant hypertension, associated with a general sympathetic stimulation, including an increase in the turnover of norepinephrine in the heart." | 1.28 | Alterations in brainstem alpha 2 adrenoreceptor activity in pyridoxine-deficient rat model of hypertension. ( Dakshinamurti, K; Lal, KJ; Paulose, CS; Sharma, SK; Viswanathan, M, 1990) |
| "Clonidine was microinjected into the AHA of rats maintained on the four diets for 2 weeks to test the hypothesis that dietary Ca2+ supplementation prevents the previously observed NaCl-induced upregulation of alpha 2-adrenoceptors in AHA." | 1.28 | Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats by a sympatholytic mechanism. ( Chen, YF; Jin, HK; Oparil, S; Wyss, JM; Yang, RH, 1990) |
| "Hypokalemia was found by normal urine excretion of potassium and normal intraerythrocyte potassium contents." | 1.28 | [Hypokalemia caused by nifedipine]. ( Angelova, I; Kundurdzhiev, A; Popiliev, I, 1990) |
| "Patients suffering of parodontosis and hypertensive disease (stage II) revealed an increase of the microcirculatory blood vessels of the periodontal tissues and correspondingly a deterioration of circulation in the region of the microcirculatory bed, a reduction of the stability of microcirculatory blood vessels of the periodontal tissues." | 1.28 | [The local use of clofelin in the combined treatment of patients with periodontosis and hypertension]. ( Zanozdra, LN, 1990) |
| "A major risk associated with the acute treatment of severe hypertension is a reduction in cerebral blood flow (CBF) with ischemic injury to the central nervous system." | 1.28 | Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine. ( Brown, FD; Cervenka, K; Greene, CS; Gretler, DD; McCoy, CE; Murphy, MB, 1990) |
| "Labetalol was administered at the conclusion of surgery as a 20-mg bolus over two minutes followed by 40 mg every 10 minutes until the desired BP was achieved (BP less than or equal to 10% above average preoperative BP or less than 150 mmHg, systolic) or 300 mg had been given." | 1.28 | Intravenous labetalol for the treatment of hypertension after carotid endarterectomy. ( Azad, SS; Goldberg, ME; Larijani, GE; Marr, AT; Seltzer, JL; Smullens, SN, 1989) |
| "Using a sensitive and specific radioimmunoassay the pharmacokinetic disposition of clonidine was determined in hypertensive patients after a single dose and then after 5, 28 and 56 days of chronic dosing with 75 micrograms bd." | 1.28 | Pharmacokinetics and antihypertensive effects of low dose clonidine during chronic therapy. ( Anavekar, SN; Conway, EL; Howes, LG; Jarrott, B; Louis, WJ; Syrjanen, M, 1989) |
| " Compound 9d, which lowered arterial blood pressure 37 mmHg in SHR when dosed at 100 mg/kg, was further evaluated in chronic hypertensive dogs because of apparent minimal CNS effects." | 1.27 | N2-(4-Substituted-2,6-dichlorophenyl)-N1,N1-dimethylformamidines as antihypertensive and diuretic agents. ( Chan, PS; Emma, JE; Meyer, WE; Tomcufcik, AS, 1984) |
| "In nifedipine-treated rats, the pressor actions of guanabenz and clonidine were virtually abolished, while the onset of the depressor responses were significantly accelerated." | 1.27 | Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats. ( Lappe, RW; Saslow, BA; Wendt, RL, 1984) |
| "A clonidine treatment had been stopped 129 h earlier." | 1.27 | [Withdrawal syndrome during epidural administration of morphine after stopping treatment with clonidine]. ( Oksenhendler, G; Petit, J; Ropiquet, S; Winckler, C, 1984) |
| "Three months after colectomy for severe ulcerative colitis, an 18-year-old male presented with a multisystem illness characterized by fever, arthralgias, hypertension, and declining renal function." | 1.27 | Polyarteritis nodosa associated with ulcerative colitis. ( Silverman, MH, 1984) |
| "3) Clonidine was administered orally in a single dose of 150 micrograms to seven patients with s-EH and three patients with b-EH, and PNE, PE and growth hormone (GH) were measured before and after the administration." | 1.27 | [Studies on the role of the central and peripheral sympathetic nervous system and the renin-aldosterone system on the onset and maintenance of high blood pressure in essential hypertension]. ( Shigetomi, S, 1983) |
| " However, chronic use of clonidine-TTS was accompanied by a high frequency of contact dermatitis (type IV allergy) in nearly half of our patients (n = 15, 47%)." | 1.27 | Transdermal clonidine application: long-term results in essential hypertension. ( Foerster, E; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W, 1984) |
| " The dosage of clonidine was progressively increased until a normal BP (mean BP less than or equal to 105 mmHg) was obtained." | 1.27 | Changes in cardiac function after effective treatment of hypertensive emergencies with i.v. clonidine. ( Bisi, G; Gallini, C; Masotti, G; Neri Serneri, GG; Poggesi, L; Scarti, L, 1984) |
| "When clonidine was given in a dose of 0." | 1.27 | Interaction of clonidine and labetalol in hypertension. ( Lilja, M, 1983) |
| "Clonidine has been reported to adversely affect glucose tolerance in experimental animals and normal man." | 1.27 | Clonidine in patients with diabetes and mild hypertension. ( Guthrie, GP; Koenig, SH; Kotchen, TA; Miller, RE, 1983) |
| "Clonidine was given orally as monotherapy in increasing daily doses from 3." | 1.27 | Relationship between the cardiovascular effects and steady-state kinetics of clonidine in hypertension. Demonstration of a therapeutic window in man. ( Frisk-Holmberg, M; Paalzow, L; Wibell, L, 1984) |
| "(4) Clonidine was 100 percent bioavailable in tablets and Perlongets." | 1.27 | New aspects of the clinical pharmacology of clonidine. ( Arndts, D, 1983) |
| "The other two patients with idiopathic orthostatic hypotension had an even greater pressor response to 0." | 1.27 | Clonidine raises blood pressure in severe idiopathic orthostatic hypotension. ( Goldberg, MR; Hollister, AS; Robertson, D; Robertson, RM; Wade, D, 1983) |
| " While acute studies in humans have demonstrated weight gain and sodium retention with clonidine and guanabenz, chronic administration results in a decrease in weight and plasma volume." | 1.27 | Effects of alpha-2 agonists on renal function in hypertensive humans. ( Gehr, M; Goldberg, M, 1985) |
| "Clonidine was administered intravenously in a dose of 5 micrograms/kg over a 5-min period." | 1.27 | Hemodynamic effects of clonidine in patients with acute myocardial infarction complicated by hypertension. ( Foresti, A; Lotto, A; Massari, FM, 1986) |
| " The dosage of clonidine was progressively increased until a normal blood pressure (mean blood pressure less than or equal to 105 mm Hg) was obtained." | 1.27 | Treatment of hypertensive emergencies: classic and newer approaches. ( Bisi, G; Gallini, C; Masotti, G; Neri Serneri, GG; Poggesi, L; Scarti, L; Sciagrà, R, 1986) |
| " In Sprague-Dawley rats made hypertensive by chronic administration of deoxycorticosterone pivalate and salt, the hypotensive and bradycardic effects of intra-NTS clonidine were inhibited by ICI 174864, but not by beta-funaltrexamine, a pattern similar to that in SHR, but different from that in normotensive Sprague-Dawley rats." | 1.27 | Opiate receptors and the endorphin-mediated cardiovascular effects of clonidine in rats: evidence for hypertension-induced mu-subtype to delta-subtype changes. ( Kunos, G; Mosqueda-Garcia, R, 1987) |
| "Clonidine can produce symptomatic sinus bradycardia or atrioventricular (AV) block in some patients." | 1.27 | Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers. ( Nadeau, JH; Primm, RK; Roden, DM, 1988) |
| "Clonidine produced an increase of cGMP content and a decrease of the endogenous type II inhibitor of protein kinase in rat hypothalamic slices." | 1.27 | Changed sensitivity of alpha 2-adrenoceptors mediating a decrease in protein kinase inhibitor activity in the brain of vasopressin-hypertensive rats. ( Starke, K; Szadowska, A; Szmigielska, H; Szmigielski, A, 1986) |
| "Prazosin has been reported to reduce the hypotensive and/or bradycardic effect of clonidine in various animal models." | 1.27 | Prazosin partly blocks clonidine-induced hypotension in patients with essential hypertension. ( Farsang, C; Kapocsi, J; Vizi, ES, 1987) |
| " A dose-response relationship was found for the hypotensive effect of i." | 1.27 | Beta-endorphin: a common factor in the antihypertensive action of clonidine-type imidazolines in spontaneously hypertensive rats. ( Fernandez-Roman, M; Fuentes, JA; Naranjo, JR; Urdin, MC, 1985) |
| "Treatment with clonidine for 14 days normalized low beta-endorphin, high plasma noradrenaline and high blood pressure in essential hypertensives at rest, but had no effect in controls." | 1.27 | Reduced beta-endorphin secretion in young patients with mild essential hypertension at rest and during exercise. ( Behrendt, M; Kolloch, R; Kraft, KS; Stumpe, KO, 1988) |
| " Its frequency is influenced by length of treatment, daily dosage and degree of hypertension." | 1.27 | [Hypertensive crisis after withdrawal of clonidine and nadolol. Case report and review of the literature]. ( Fried, M; Schwander, J, 1987) |
| "Urgent hypertension is defined by severe elevations of blood pressure without associated end-organ damage." | 1.27 | Management of urgent hypertension: a comparison of oral treatment regimens in the emergency department. ( Catapano, MS; Marx, JA, 1986) |
| "DOCA-salt hypertension was associated with hyporeninemia and mild hypokalemia, without consistent changes in heart rate or plasma catecholamines." | 1.27 | Production and reversal of DOCA-salt hypertension in baboons. ( Goldstein, DS; Turkkan, JS, 1987) |
| "Hypertension due to pheochromocytoma is generally considered to be a straightforward, direct consequence of the elevated concentrations of circulating catecholamines." | 1.27 | Role of the sympathetic nervous system in the maintenance of hypertension in rats harboring pheochromocytoma. ( Hoffman, BB; Maze, M; Prokocimer, PG, 1987) |
| "dose, a tachycardia was observed in all rats following initial transient bradycardia." | 1.27 | Tachycardic and hypertensive effects of centrally administered clonidine in conscious rats. ( Imai, Y; Johnston, CI; Nolan, PL, 1986) |
| " The slope of the dose-response curves was similar in both strains of rat, but the average response to the same concentrations of clonidine was less in the SHR." | 1.27 | Modification of clonidine-induced pressor responses in morphine-dependent and hypophysectomised rats. ( Conway, EL, 1986) |
| " In some of the pithed rats dose-response curves were constructed to exogenously administered noradrenaline (NA) and sympathetic nerve stimulation (SNS) through the pithing rod before and after the administration of an inhibitor of the neuronal uptake mechanism (desipramine, DMI, 0." | 1.27 | A low dietary sodium intake reduces neuronal noradrenaline release and the blood pressure in spontaneously hypertensive rats. ( Dahlöf, C; Gradin, K; Persson, B, 1986) |
| "The paroxysmal hypertension is believed to have resulted from the synergistic effect of the high levels of circulating catecholamines from the tumor and the disruption of autonomic pathways." | 1.27 | Autonomic dysreflexia in a paraplegic man with catecholamine-secreting neuroblastoma. ( Agre, JC; Theologides, A; Wilson, BC; Wright, KC, 1986) |
| "Clonidine was ineffective (WKY) or caused moderate hyperalgesia (SHR)." | 1.27 | Naloxone reverses the antinociceptive action of clonidine in spontaneously hypertensive rats. ( Abbott, FV; Kunos, G; Ramirez-Gonzalez, MD; Tchakarov, L, 1985) |
| "Naloxone was found to reverse this hypoalgesic state." | 1.27 | Association between hypoalgesia and hypertension in rats after short-term isolation. ( Fuentes, JA; Naranjo, JR, 1985) |
| " Since the alpha-adrenoceptor blocking drugs which, at the usual dosage level, antagonize the hypotensive action of clonidine are unknown in man, caution should be exercised for such an association clonidine-alpha-blocker." | 1.26 | [Interaction between clonidine and alpha-blockers (author's transl)]. ( Chelly, J; Huchet, AM; Schmitt, H, 1980) |
| "Clonidine was given in doses of 0." | 1.26 | Clonidine and prazosin effects in hypernoradrenergic vasodilator-treated and beta-blocker-treated patients. ( Mitchell, HC; Pettinger, WA, 1981) |
| " Chronic administration of propranolol to SHR for three consecutive weeks by Alzet minipump reduced systolic arterial pressure but did not reverse the indices of myocardial hypertrophy." | 1.26 | Effect of chronic administration of clonidine and propranolol on the myocardium of spontaneously hypertensive rats. ( Greenberg, S; Wilborn, WM, 1982) |
| "Guanfacine treated SHR showed less change in water drinking behavior and ambulation than the clonidine treated SHR." | 1.26 | Effects of clonidine and guanfacine on drinking and ambulation in spontaneously hypertensive rats. ( Bando, Y; Koike, Y; Minami, M; Saito, H; Shimamura, K; Togashi, H, 1982) |
| " The vasodepressor effect of guanfacine was clearly dose-dependent, and was more marked when the initial level of the blood pressure was high, while that of clonidine was dose-dependent, only within a limited dosage range." | 1.26 | [Antihypertensive effect of guanfacine in rats]. ( Hamamura, M; Hashimoto, T; Imai, S; Kumada, M; Mitomi, A; Nakagawa, Y; Sakurai, H; Takeda, K, 1981) |
| " Chronic administration of obsidan (0." | 1.26 | [Clinical and experimental study of the effect of obsidan and hemiton on the blood kallikrein-kinin system]. ( Abdullina, RN; Akhmetova, BKh; Davidenko, IuD; Didenko, RG, 1982) |
| " On the other hand, long-term administration of guanfacine at a dose of approximately 3 mg/kg/day produced a significant hypotension." | 1.26 | Effects of abrupt cessation of treatment with clonidine and guanfacine on blood pressure and heart rate in spontaneously hypertensive rats. ( Koike, Y; Saito, H; Shimamura, K; Togashi, H; Yomaida, I, 1981) |
| "Clonidine was administered at a daily dose of 0,15 to 0,30 mg to 10 non-obese diabetic hypertensive male subjects for at least 3 months." | 1.26 | [Effect of long-term administration of clonidine on growth hormone secretion in hypertensive diabetics]. ( Canivet, J; Gauvillé, C; Leblanc, H; Passa, P; Tabuteau, F, 1982) |
| "The present experiments were undertaken to elucidate the effect of long-term administration of clonidine and its cessation on blood pressure, heart rate and sympathetic nerve activity in spontaneously hypertensive rats (SHR)." | 1.26 | [Effects of long-term administration and cessation of clonidine on blood pressure in spontaneously hypertensive rats (author's transl)]. ( Yomaida, I, 1980) |
| "Treatment with clonidine (1 mg/kg, b." | 1.26 | Thermoregulation in spontaneously hypertensive rats: effects of antihypertensive treatments. ( O'Donnell, A; Volicer, L, 1981) |
| " The age, degree of renal impairment, plasma renin activity, and number and dosage of antihypertensive medicines did not account for these differences in NE." | 1.26 | Effect of antihypertensive therapy on plasma catecholamines in renal failure patients. ( Anderson, S; Cronin, R; Henrich, WL; Mitchell, H; Pettinger, WA, 1981) |
| " The blood pressure reduction in patients with essential hypertension was satisfactory on this regimen and the steady-state plasma concentrations were within the BP-lowering concentration range at the end of a dosage interval." | 1.26 | The effectiveness of clonidine as an antihypertensive in a two-dose regimen. ( Frisk-Holmberg, M, 1980) |
| "Renal disease and hypertension is a continuing challenge to the nephrologist." | 1.26 | The kidney and antihypertensive therapy. ( Bailey, RR, 1976) |
| "Complications of hypertension are by far the greatese preventable public health problem in many of the developed countries of the world." | 1.26 | Additive effect of beta-adrenergic blockers in combination with vasodilators in lowering blood pressure. ( Mitchell, HC; Pettinger, WA, 1976) |
| "Occasional or recurrent episodes of orthostatic hypotension were observed in 58 out of 584 hypertensive patients treated with alpha-methyldopa, beta-blockers and clonidine alone or associated with diuretics and/or hydralazine and/or reserpine." | 1.26 | [The orthostatic hypotension in patients treated with antihypertensive drugs (author's transl)]. ( Dal Palù, C; Pessina, AC; Pigato, R, 1977) |
| "Prazosin appears to be a suitable substitute for hydralazine as an effective vasodialator if thiazides plus propranolol or thiazides plus reserpine or alpha-methyldopa are not effective." | 1.26 | Propranolol and newer antihypertensive drugs in the management of hypertension. ( Moser, M, 1979) |
| "Clonidine therapy was discontinued abruptly in seven patients." | 1.26 | Abrupt discontinuation of clonidine therapy. ( Engelman, K; Ram, CV, 1979) |
| "28 ng/ml) and plasma half-life (10." | 1.26 | Pharmacokinetic and concentration-effect relationships of clonidine in essential hypertension. ( Davies, DS; Dollery, CT; Neill, EA; Reid, JL; Tippett, P; Wing, LM, 1977) |
| " 2 Clonidine disposition could be described by a two compartment open model and pharmacokinetic parameters show a rapid distribution phase of 20--30 min and a mean plasma clearance of 4." | 1.26 | Pharmacokinetics of clonidine and its relation to the hypotensive effect in patients. ( Edlund, PO; Frisk-Holmberg, M; Paalzow, L, 1978) |
| "The major reason for treating hypertension is to avoid complications of the disease as it affects "target organs." | 1.26 | Prevention of some complications of essential hypertension. ( Grissom, RL; Gust, WF, 1977) |
| "Among 42 patients converted from clonidine to another antihypertensive medication, few sympathomimetic side effects were observed if the clonidine dosage had been less than 1." | 1.26 | Central nervous system actions of clonidine in hypertension. ( Hoobler, SW; Kashima, T, 1977) |
| "Xipamide was given in combination with clonidine hydrochloride." | 1.26 | Studies covering combined treatments with xipamide. Results of a long-term antihypertensive treatment. ( Heimsoth, VH, 1977) |
| "6 Labetalol is a useful addition to the medical treatment of phaeochromocytoma." | 1.26 | Treatment of phaeochromocytoma and of clonidine withdrawal hypertension with labetalol. ( Brown, JJ; Lever, AF; Robertson, AS; Robertson, JI; Rosei, EA; Trust, PM, 1976) |
| "Clonidine hydrochloride is a new antihypertensive agent with a primary site of action in the central nervous system." | 1.25 | Evaluation of clonidine hydrochloride (Catapres). A new antihypertensive agent. ( Kosman, ME, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 998 (72.58) | 18.7374 |
| 1990's | 233 (16.95) | 18.2507 |
| 2000's | 85 (6.18) | 29.6817 |
| 2010's | 47 (3.42) | 24.3611 |
| 2020's | 12 (0.87) | 2.80 |
| Authors | Studies |
|---|---|
| Warren, JD | 1 |
| Woodward, DL | 1 |
| Hargreaves, RT | 1 |
| Huber, D | 1 |
| Ehrhardt, JD | 1 |
| Decker, N | 1 |
| Himber, J | 1 |
| Andermann, G | 1 |
| Leclerc, G | 1 |
| Meyer, WE | 2 |
| Tomcufcik, AS | 2 |
| Chan, PS | 2 |
| Haug, M | 1 |
| Emma, JE | 1 |
| Davis, L | 1 |
| Agnew, MN | 1 |
| Effland, RC | 1 |
| Klein, JT | 1 |
| Kitzen, JM | 1 |
| Schwenkler, MA | 1 |
| Bennett, LR | 1 |
| Blankley, CJ | 1 |
| Fleming, RW | 1 |
| Smith, RD | 2 |
| Tessman, DK | 2 |
| Malhotra, V | 1 |
| Vats, M | 1 |
| Nath, R | 1 |
| Mehta, S | 1 |
| Kumar, R | 1 |
| Bhalla, M | 1 |
| Sinha, JN | 1 |
| Shanker, K | 2 |
| Pathak, SR | 1 |
| Hanna, J | 1 |
| Ghazi, L | 1 |
| Yamamoto, Y | 1 |
| Simonov, M | 1 |
| Shah, T | 1 |
| Wilson, FP | 1 |
| Peixoto, AJ | 2 |
| Laffer, CL | 1 |
| Elijovich, F | 1 |
| Tsiomidou, S | 1 |
| Pamporaki, C | 1 |
| Geroula, A | 1 |
| Van Baal, L | 1 |
| Weber, F | 1 |
| Dralle, H | 1 |
| Schmid, KW | 1 |
| Führer, D | 1 |
| Unger, N | 1 |
| Viet-Quoc Nguyen, P | 1 |
| Le Berre, C | 1 |
| Fillion, L | 1 |
| Lafleur, M | 1 |
| Shi, YF | 1 |
| Jiang, YP | 1 |
| Wang, XZ | 1 |
| Sun, PP | 1 |
| Zhu, NJ | 1 |
| Wang, K | 1 |
| Zhang, ZQ | 1 |
| Liu, YY | 1 |
| Huo, J | 1 |
| Wang, XR | 1 |
| Ding, B | 1 |
| Zicha, J | 3 |
| Řezáčová, L | 3 |
| Behuliak, M | 3 |
| Vaněčková, I | 3 |
| Boivin, JM | 1 |
| Luther, JM | 1 |
| Dominiczak, AF | 1 |
| Jennings, GLR | 1 |
| VanDevender, FK | 1 |
| Carey, RM | 1 |
| Chung, CP | 1 |
| Oates, JA | 3 |
| Doumas, M | 1 |
| Imprialos, KP | 1 |
| Kallistratos, MS | 1 |
| Manolis, AJ | 1 |
| Golani, T | 1 |
| Fishman, B | 1 |
| Sharabi, Y | 2 |
| Olswang-Kutz, Y | 1 |
| Leibowitz, A | 1 |
| Grossman, E | 3 |
| Shlomai, G | 1 |
| Mendonça, MM | 1 |
| Costa, AN | 1 |
| Moraes, GCA | 1 |
| Martins, GM | 1 |
| Almeida, AF | 1 |
| Rincon, GCN | 1 |
| Siqueira, JPR | 1 |
| Padilha, DM | 1 |
| Moya, MI | 1 |
| Ferreira-Neto, ML | 1 |
| Gomes, RM | 1 |
| Pedrino, GR | 1 |
| Fontes, MAP | 1 |
| Colombari, E | 1 |
| Crestani, CC | 1 |
| Fajemiroye, JO | 1 |
| Xavier, CH | 1 |
| Miller, DL | 1 |
| Dou, C | 1 |
| Raghavendran, K | 1 |
| Dong, Z | 1 |
| Anderson, PO | 1 |
| Krieger, EM | 2 |
| Drager, LF | 2 |
| Giorgi, DMA | 1 |
| Pereira, AC | 2 |
| Barreto-Filho, JAS | 1 |
| Nogueira, AR | 1 |
| Mill, JG | 2 |
| Lotufo, PA | 1 |
| Amodeo, C | 1 |
| Batista, MC | 1 |
| Bodanese, LC | 1 |
| Carvalho, ACC | 1 |
| Castro, I | 1 |
| Chaves, H | 1 |
| Costa, EAS | 1 |
| Feitosa, GS | 1 |
| Franco, RJS | 1 |
| Fuchs, FD | 1 |
| Guimarães, AC | 1 |
| Jardim, PC | 1 |
| Machado, CA | 1 |
| Magalhães, ME | 1 |
| Mion, D | 1 |
| Nascimento, RM | 1 |
| Nobre, F | 1 |
| Nóbrega, AC | 1 |
| Ribeiro, ALP | 1 |
| Rodrigues-Sobrinho, CR | 1 |
| Sanjuliani, AF | 1 |
| Teixeira, MDCB | 1 |
| Krieger, JE | 2 |
| Taguchi, K | 1 |
| Bessho, N | 1 |
| Hasegawa, M | 1 |
| Narimatsu, H | 1 |
| Matsumoto, T | 1 |
| Kobayashi, T | 2 |
| Seger, DL | 2 |
| Loden, JK | 1 |
| Yamazato, M | 2 |
| Nakamoto, M | 1 |
| Sakima, A | 1 |
| Yamazato, Y | 1 |
| Takishita, S | 3 |
| Ohya, Y | 1 |
| Oyama, JI | 1 |
| Node, K | 1 |
| Zidek, W | 1 |
| Preston, RA | 4 |
| Arciniegas, R | 1 |
| DeGraff, S | 1 |
| Materson, BJ | 6 |
| Bernstein, J | 1 |
| Afshartous, D | 1 |
| Schuster Bruce, C | 1 |
| Rull, G | 1 |
| Sotiris, A | 1 |
| Lobo, MD | 1 |
| Minhaj, FS | 1 |
| Schult, RF | 1 |
| Dvorak, P | 1 |
| Nacca, N | 1 |
| Leavitt, K | 1 |
| Običan, S | 1 |
| Yankowitz, J | 1 |
| Prescott, A | 1 |
| Smereck, J | 1 |
| Sanders, P | 1 |
| Nik Yusoff, NS | 1 |
| Mustapha, Z | 1 |
| Govindasamy, C | 1 |
| Sirajudeen, KN | 1 |
| Noronha-Neto, C | 1 |
| Katz, L | 1 |
| Coutinho, IC | 1 |
| Maia, SB | 1 |
| Souza, AS | 1 |
| Amorim, MM | 1 |
| Pomerleau, AC | 1 |
| Gooden, CE | 1 |
| Fantz, CR | 1 |
| Morgan, BW | 1 |
| Giorgi, DM | 1 |
| Barreto-Filho, JA | 1 |
| da Rocha Nogueira, A | 1 |
| Chen, J | 1 |
| Zhao, X | 1 |
| Wang, H | 1 |
| Chen, Y | 2 |
| Wang, W | 2 |
| Zhou, W | 1 |
| Wang, X | 1 |
| Tang, J | 1 |
| Zhao, Y | 1 |
| Lu, X | 1 |
| Chen, S | 2 |
| Wang, L | 1 |
| Shen, C | 1 |
| Yang, S | 1 |
| Malaty, J | 1 |
| Malaty, IA | 1 |
| Lin, LL | 1 |
| Wang, D | 1 |
| Cheng, YQ | 1 |
| Su, DF | 3 |
| Liu, AJ | 2 |
| Garcha, AS | 1 |
| Cohen, DL | 1 |
| Komanski, CB | 1 |
| Rauck, RL | 1 |
| North, JM | 1 |
| Hong, KS | 1 |
| D'Angelo, R | 1 |
| Hildebrand, KR | 1 |
| Jabaris, SS | 1 |
| Sumathy, H | 1 |
| Girish, R | 1 |
| Narayanan, S | 1 |
| Sugumar, M | 1 |
| Saravana Babu, C | 1 |
| Thanikachalam, S | 1 |
| Thanikachalam, M | 1 |
| Kienstra, CM | 1 |
| Hergenroeder, AC | 1 |
| Riley, AA | 1 |
| Justino, H | 1 |
| Chim, C | 1 |
| Dimitropoulos, E | 1 |
| Ginzburg, R | 1 |
| Kaplan, NM | 4 |
| Chisholm, P | 1 |
| Anpalahan, M | 1 |
| Liatsi, D | 1 |
| Tsapas, B | 1 |
| Pampori, S | 1 |
| Tsagourias, M | 1 |
| Pneumatikos, I | 1 |
| Matamis, D | 1 |
| Schlaich, MP | 1 |
| Socratous, F | 1 |
| Hennebry, S | 1 |
| Eikelis, N | 2 |
| Lambert, EA | 1 |
| Straznicky, N | 1 |
| Esler, MD | 1 |
| Lambert, GW | 1 |
| Moura, E | 2 |
| Afonso, J | 1 |
| Serrão, MP | 1 |
| Vieira-Coelho, MA | 2 |
| Olatunji, LA | 1 |
| Soladoye, AO | 1 |
| Buchanan, ML | 1 |
| Easterling, TR | 1 |
| Carr, DB | 1 |
| Shen, DD | 1 |
| Risler, LJ | 1 |
| Nelson, WL | 1 |
| Mattison, DR | 1 |
| Hebert, MF | 1 |
| Morimoto, S | 2 |
| Aota, Y | 2 |
| Sakuma, T | 2 |
| Ichibangase, A | 1 |
| Ikeda, K | 2 |
| Sawada, S | 2 |
| Iwasaka, T | 2 |
| Wallace, EL | 1 |
| Lingle, K | 1 |
| Pierce, D | 1 |
| Satko, S | 1 |
| Kamari, Y | 1 |
| Shimoni, N | 1 |
| Koren, F | 1 |
| Peleg, E | 1 |
| Nascimento, AR | 1 |
| Lessa, MA | 1 |
| Sabino, B | 1 |
| Bousquet, P | 6 |
| Tibiriçá, E | 4 |
| II'nitskiĭ, AN | 1 |
| Proshchaev, KI | 2 |
| Zaradeĭ, II | 1 |
| Almukhov, AA | 1 |
| Aksenov, DV | 1 |
| Kniaz'kin, IV | 1 |
| Safonov, IS | 1 |
| Takahashi, N | 1 |
| Toyoda, N | 1 |
| Kosaki, A | 1 |
| Maehara, M | 1 |
| Tanigawa, N | 1 |
| Varoni, MV | 1 |
| Palomba, D | 1 |
| Macciotta, NP | 1 |
| Antuofermo, E | 1 |
| Deiana, G | 1 |
| Baralla, E | 1 |
| Anania, V | 1 |
| Demontis, MP | 1 |
| Ghannoum, JE | 1 |
| Odingo, NA | 1 |
| Provost, N | 1 |
| Gayen, JR | 1 |
| Zhang, K | 1 |
| RamachandraRao, SP | 1 |
| Mahata, M | 1 |
| Kim, HS | 1 |
| Naviaux, RK | 1 |
| Sharma, K | 1 |
| Mahata, SK | 1 |
| O'Connor, DT | 5 |
| El-Mas, MM | 5 |
| Abdel-Rahman, AA | 6 |
| Bassareo, PP | 1 |
| Marras, AR | 1 |
| Mercuro, G | 2 |
| Vorobyov, V | 1 |
| Schibaev, N | 1 |
| Kaptsov, V | 1 |
| Kovalev, G | 1 |
| Sengpiel, F | 1 |
| Slim, HB | 1 |
| Black, HR | 2 |
| Thompson, PD | 1 |
| Ruksin, VV | 1 |
| Grishin, OV | 1 |
| Patil, PM | 1 |
| Patil, SP | 1 |
| Pandazi, A | 1 |
| Karamanis, P | 1 |
| Sidiropoulou, T | 1 |
| Matsota, P | 1 |
| Papasideris, C | 1 |
| Niokou, D | 1 |
| Kostopanagiotou, G | 1 |
| Vuylsteke, A | 1 |
| Vincent, JL | 1 |
| de La Garanderie, DP | 1 |
| Anderson, FA | 1 |
| Emery, L | 1 |
| Wyman, A | 1 |
| Rushton-Smith, S | 1 |
| Gore, JM | 1 |
| Yoon, EY | 1 |
| Cohn, L | 1 |
| Rocchini, A | 1 |
| Kershaw, D | 1 |
| Clark, SJ | 1 |
| Isabelle, M | 1 |
| Simonet, S | 1 |
| Ragonnet, C | 1 |
| Sansilvestri-Morel, P | 1 |
| Clavreul, N | 1 |
| Vayssettes-Courchay, C | 1 |
| Verbeuren, TJ | 1 |
| Moon, HS | 1 |
| Chon, JY | 1 |
| Zoladz, PR | 1 |
| Fleshner, M | 1 |
| Diamond, DM | 1 |
| Ye, S | 1 |
| Zhong, H | 1 |
| Yanamadala, V | 1 |
| Campese, VM | 5 |
| Backo, AL | 1 |
| Clause, SL | 1 |
| Triller, DM | 1 |
| Gibbs, KA | 1 |
| Bravo, EL | 6 |
| Head, GA | 2 |
| Hashimoto, J | 1 |
| Chonan, K | 1 |
| Aoki, Y | 1 |
| Ugajin, T | 1 |
| Yamaguchi, J | 1 |
| Nishimura, T | 1 |
| Kikuya, M | 1 |
| Michimata, M | 1 |
| Matsubara, M | 1 |
| Araki, T | 1 |
| Hozawa, A | 1 |
| Ohkubo, T | 1 |
| Imai, Y | 4 |
| Schlaich, M | 1 |
| Aggarwal, A | 1 |
| Kaye, D | 1 |
| Esler, M | 3 |
| Denolle, T | 1 |
| Sassano, P | 1 |
| Allain, H | 1 |
| Bentué-Ferrer, D | 1 |
| Breton, S | 1 |
| Cimarosti, I | 1 |
| Ouatara, B | 1 |
| Merienne, M | 1 |
| Gandon, JM | 1 |
| Velliquette, RA | 1 |
| Ernsberger, P | 4 |
| Gorzalczany, SB | 1 |
| Opezzo, JA | 2 |
| del Carmen Garcia, M | 1 |
| Taira, CA | 3 |
| Stiefelhagen, P | 1 |
| Del Bo, A | 3 |
| Oliveira-Filho, J | 1 |
| Silva, SC | 1 |
| Trabuco, CC | 1 |
| Pedreira, BB | 1 |
| Sousa, EU | 1 |
| Bacellar, A | 1 |
| Simic, J | 1 |
| Kishineff, S | 1 |
| Goldberg, R | 1 |
| Gifford, W | 1 |
| Tsuda, K | 1 |
| Tsuda, S | 1 |
| Nishio, I | 1 |
| Rocchini, AP | 2 |
| Yang, JQ | 1 |
| Gokee, A | 1 |
| Amador, N | 1 |
| Pérez-Luque, E | 1 |
| Malacara, JM | 1 |
| Guízar, JM | 1 |
| Paniagua, R | 1 |
| Lara, S | 1 |
| Schrader, J | 1 |
| Diener, HC | 1 |
| Lüders, S | 1 |
| Sharma, V | 1 |
| Watschinger, B | 1 |
| Habicht, A | 1 |
| Gómez Esteban, JC | 1 |
| Boyero, S | 1 |
| Fernández, C | 1 |
| Sagasta, A | 1 |
| Pérez, T | 1 |
| Velasco, F | 1 |
| Allue, I | 1 |
| Lezcano, E | 1 |
| Zarranz, JJ | 1 |
| de Moura, RS | 1 |
| Miranda, DZ | 1 |
| Pinto, AC | 1 |
| Sicca, RF | 1 |
| Souza, MA | 1 |
| Rubenich, LM | 1 |
| Carvalho, LC | 1 |
| Rangel, BM | 1 |
| Tano, T | 1 |
| Madeira, SV | 1 |
| Resende, AC | 1 |
| Golikov, AP | 1 |
| Spiller, HA | 1 |
| Klein-Schwartz, W | 1 |
| Colvin, JM | 1 |
| Villalobos, D | 1 |
| Johnson, PB | 1 |
| Anderson, DL | 1 |
| de Leeuw, PW | 2 |
| Roos, M | 1 |
| Sica, DA | 2 |
| Grubbs, R | 1 |
| Briaud, S | 1 |
| Zhang, BL | 1 |
| Sannajust, F | 2 |
| Shibao, C | 1 |
| Gamboa, A | 1 |
| Abraham, R | 1 |
| Raj, SR | 1 |
| Diedrich, A | 1 |
| Black, B | 1 |
| Robertson, D | 6 |
| Biaggioni, I | 2 |
| Handler, J | 1 |
| Delaney, J | 1 |
| Spevack, D | 1 |
| Doddamani, S | 1 |
| Ostfeld, R | 1 |
| Moser, M | 2 |
| Izzo, JL | 2 |
| Bisognano, J | 1 |
| Füessl, HS | 1 |
| Wang, J | 1 |
| Shen, FM | 2 |
| Wang, MW | 1 |
| Raptis, L | 1 |
| Pappas, G | 1 |
| Katsanou, A | 1 |
| Koutsouka, F | 1 |
| Petrakis, D | 1 |
| Akritidis, N | 1 |
| Ma, RC | 1 |
| Yiu, KH | 1 |
| Wong, EH | 1 |
| Liu, KH | 1 |
| Chan, JY | 1 |
| Chow, CC | 1 |
| Cockram, CS | 1 |
| Mayer, MA | 1 |
| Höcht, C | 1 |
| Fernández, BE | 1 |
| Puyó, AM | 1 |
| Hajduk, A | 1 |
| Sein Anand, J | 1 |
| Chodorowski, Z | 1 |
| Margolis, KL | 1 |
| Piller, LB | 1 |
| Ford, CE | 1 |
| Henriquez, MA | 1 |
| Cushman, WC | 4 |
| Einhorn, PT | 1 |
| Colon, PJ | 1 |
| Vidt, DG | 3 |
| Christian, R | 1 |
| Wong, ND | 1 |
| Wright, JT | 1 |
| Goff, DC | 1 |
| Ma, XJ | 1 |
| Shi, KY | 1 |
| Wu, YL | 1 |
| Adeishvili-Anguladze, LV | 1 |
| Makharadze, RV | 1 |
| Kurtsikidze, MSh | 1 |
| Abuladze, NB | 1 |
| Kintsurashvili, KM | 1 |
| Cividjian, A | 1 |
| Rentero, N | 1 |
| Quintin, L | 7 |
| Wallenborn, J | 1 |
| Thieme, V | 1 |
| Hertel-Gilch, G | 1 |
| Gräfe, K | 1 |
| Richter, O | 1 |
| Schaffranietz, L | 1 |
| Sartori, M | 1 |
| Cosenzi, A | 2 |
| Bernobich, E | 1 |
| Calo, LA | 1 |
| Bellini, G | 2 |
| Semplicini, A | 1 |
| Oktar, S | 1 |
| Ilhan, S | 1 |
| Aksulu, HE | 1 |
| Lappe, RW | 1 |
| Saslow, BA | 1 |
| Wendt, RL | 1 |
| Bühler, FR | 1 |
| Bolli, P | 2 |
| Amann, WF | 1 |
| Erne, P | 1 |
| Kiowski, W | 1 |
| Weber, MA | 16 |
| Drayer, JI | 12 |
| Farsang, C | 13 |
| Varga, K | 7 |
| Vajda, L | 7 |
| Kapocsi, J | 10 |
| Balás-Eltes, A | 2 |
| Kunos, G | 14 |
| Ropiquet, S | 1 |
| Petit, J | 1 |
| Oksenhendler, G | 1 |
| Winckler, C | 1 |
| Menard, J | 6 |
| Michel, JB | 1 |
| Dussaule, JC | 1 |
| Alhenc-Gelas, F | 2 |
| Corvol, P | 5 |
| Lowenstein, J | 2 |
| Huchet, AM | 1 |
| Chelly, J | 1 |
| Schmitt, H | 5 |
| Doyle, AE | 1 |
| Lilja, M | 12 |
| Jounela, AJ | 11 |
| Juustila, H | 3 |
| Mattila, MJ | 4 |
| Mashford, ML | 1 |
| Komarov, FI | 1 |
| Epikeeva, NB | 1 |
| Polunin, GS | 1 |
| Faronov, EI | 1 |
| Bullen, MU | 1 |
| Garvey, HL | 1 |
| Woodhouse, BL | 1 |
| Moodley, J | 1 |
| Halawa, B | 1 |
| Fossati, C | 1 |
| Scapellato, L | 4 |
| Stornello, M | 4 |
| Ramirez-Gonzales, MD | 1 |
| van Zwieten, PA | 16 |
| Timmermans, PB | 9 |
| Beckenbauer, U | 2 |
| Planz, G | 3 |
| Korn, A | 2 |
| Hart, GR | 2 |
| Anderson, RJ | 4 |
| Houston, MC | 6 |
| Mitchell, HC | 5 |
| Pettinger, WA | 8 |
| Shen, JQ | 1 |
| Arabidze, GG | 2 |
| Bogoslovskiĭ, VA | 1 |
| Zilcher, H | 1 |
| Weber, H | 1 |
| Polterauer, P | 1 |
| Zasmeta, H | 1 |
| Oparil, S | 11 |
| de Jonge, A | 1 |
| Goldstein, M | 1 |
| Kinguasa, K | 1 |
| Hieble, JP | 1 |
| Pendleton, RG | 1 |
| Seliuzhitskiĭ, NS | 1 |
| Juustila, HJ | 2 |
| Paalzow, L | 6 |
| Selmi, W | 1 |
| Matricardi, L | 1 |
| Lund-Johansen, P | 1 |
| Richter, R | 1 |
| Tsoucaris-Kupfer, D | 1 |
| Sambhi, MP | 5 |
| Bell, CC | 1 |
| Wirz-Justice, A | 1 |
| Kräuchi, K | 1 |
| Campbell, IC | 1 |
| Feer, H | 1 |
| Merkulova, NK | 2 |
| Martin, DE | 1 |
| Kammerer, WS | 1 |
| Zier, BG | 1 |
| Middeke, M | 1 |
| Brewer, DD | 1 |
| Lipson, JL | 1 |
| Ruffolo, RR | 2 |
| Mathy, MJ | 3 |
| Thoolen, MJ | 5 |
| Finnerty, FA | 7 |
| Evans, MG | 1 |
| Olanoff, LS | 1 |
| Hurwitz, G | 1 |
| Cowart, TD | 2 |
| Conradi, EC | 2 |
| Moyer, JH | 2 |
| Frisk-Holmberg, M | 8 |
| Su, C | 1 |
| Kubo, T | 2 |
| Chatelain, P | 1 |
| Claeys, M | 1 |
| van Dorsser, W | 1 |
| Roba, J | 2 |
| Silverman, MH | 1 |
| U'Prichard, DC | 1 |
| Lubbe, WF | 4 |
| McCaughran, JA | 1 |
| Edwards, E | 1 |
| Schechter, N | 1 |
| Friedman, R | 1 |
| Van Brummelen, P | 1 |
| Panikarskiĭ, VG | 7 |
| Prichard, BN | 1 |
| Zabetakis, PM | 1 |
| Benson, D | 1 |
| Peterson, LG | 1 |
| Bartay, J | 1 |
| Wilber, JA | 1 |
| Itskovitz, HD | 1 |
| Garrett, BN | 2 |
| Reid, JL | 15 |
| Meredith, PA | 1 |
| Elliott, HL | 4 |
| Conen, D | 4 |
| Bertel, O | 3 |
| Dubach, UC | 2 |
| Motz, W | 3 |
| Ippisch, R | 1 |
| Strauer, BE | 4 |
| Negri, L | 1 |
| Tubaldi, A | 1 |
| Giosuè, G | 1 |
| Ghergo, GF | 1 |
| Geromino, A | 1 |
| Di Pietrantonio, MG | 1 |
| Giordano, L | 1 |
| Guerrieri, R | 1 |
| Tarchini, R | 1 |
| Ricciardelli, B | 1 |
| De Luca, N | 1 |
| Volpe, M | 1 |
| Veniero, AM | 1 |
| De Simone, A | 1 |
| Cuocolo, A | 1 |
| Rosiello, G | 1 |
| Trimarco, B | 1 |
| Condorelli, M | 1 |
| Hoffman, BB | 3 |
| Lefkowitz, RJ | 1 |
| Ramirez-Gonzalez, MD | 3 |
| Mucci, L | 1 |
| Eriksson, E | 2 |
| Edén, S | 1 |
| Modigh, K | 1 |
| Cantor, EH | 1 |
| Abraham, S | 1 |
| Spector, S | 2 |
| Manhem, P | 3 |
| Heding, L | 1 |
| Malmquist, J | 1 |
| Hökfelt, B | 8 |
| Rosenthal, T | 2 |
| Rabinowitz, B | 1 |
| Boichis, H | 1 |
| Elazar, E | 1 |
| Brauner, A | 1 |
| Neufeld, HN | 1 |
| Jennings, G | 1 |
| Bobik, A | 2 |
| Korner, P | 1 |
| Webster, WB | 1 |
| McConnaughey, MM | 1 |
| Juhasz, I | 4 |
| Augustine, SJ | 1 |
| Tachikawa, S | 1 |
| Lokhandwala, MF | 1 |
| Buckley, JP | 1 |
| Louis, WJ | 6 |
| Anavekar, SN | 5 |
| Conway, EL | 5 |
| Jarrott, B | 4 |
| Caillard, CG | 1 |
| Mondot, S | 1 |
| Zundel, JL | 1 |
| Julou, L | 1 |
| McLean, K | 1 |
| Sumner, DJ | 1 |
| Malisák, Z | 4 |
| Alföldi, S | 2 |
| Qian, JQ | 1 |
| van Meel, JC | 1 |
| Rogers, JF | 1 |
| Cubeddu, LX | 3 |
| Tchakarov, L | 2 |
| Mosqueda Garcia, R | 1 |
| Yarbrough, GG | 1 |
| Taylor, DA | 1 |
| Antolik, EK | 1 |
| Robinson, EL | 1 |
| Bramnert, M | 2 |
| Fekete, M | 2 |
| Chernow, B | 2 |
| Zaloga, GP | 2 |
| Lake, CR | 2 |
| Coleman, MD | 2 |
| Ziegler, MG | 2 |
| Yaden, EL | 1 |
| Hynes, MD | 1 |
| Shigetomi, S | 1 |
| Marwaha, J | 1 |
| Kokubu, T | 1 |
| Hashimoto, H | 2 |
| Hiwada, K | 1 |
| Velasco, M | 7 |
| Silva, H | 1 |
| Morillo, J | 3 |
| Urbina-Quintana, A | 5 |
| Hernandez-Pieretti, O | 5 |
| Angeli-Greaves, M | 1 |
| Morgan, T | 1 |
| Cottier, C | 2 |
| Julius, S | 6 |
| Fahr, A | 1 |
| Förster, W | 4 |
| Taube, C | 2 |
| Huikuri, H | 1 |
| Paalzow, G | 1 |
| Vlachakis, ND | 1 |
| Velasquez, M | 1 |
| Alexander, N | 1 |
| Maronde, RF | 3 |
| Levitan, D | 1 |
| Massry, SG | 3 |
| Romoff, M | 2 |
| Plouin, PF | 1 |
| Degoulet, P | 1 |
| Fermé, I | 1 |
| Cornette, M | 1 |
| Fyhrquist, F | 2 |
| Sinha, RS | 1 |
| Hasan, M | 2 |
| Ahuja, RC | 1 |
| Bhargava, KP | 2 |
| Szucs, M | 1 |
| Green, S | 1 |
| Zawada, ET | 3 |
| Muakkassa, W | 1 |
| Johnson, M | 1 |
| Mackenzie, T | 1 |
| McClanahan, M | 1 |
| Graybill, A | 1 |
| Goldman, M | 1 |
| McMahon, FG | 8 |
| Hamburger, R | 2 |
| Shah, AR | 1 |
| Kirk, LN | 1 |
| Hubbell, FA | 2 |
| Rose, DE | 1 |
| Togashi, H | 8 |
| Minami, M | 3 |
| Saito, I | 2 |
| Sano, M | 1 |
| Ram, CV | 3 |
| Radü, EW | 1 |
| Müller, J | 2 |
| Lang, C | 1 |
| Schaffler, K | 1 |
| Hörmann, E | 1 |
| Arnold, H | 1 |
| Nicrosini, F | 1 |
| Pasotti, C | 1 |
| Hayduk, K | 2 |
| Johansson, BB | 1 |
| Auer, LM | 1 |
| McCarron, DA | 1 |
| Ishise, S | 2 |
| Pegram, BL | 3 |
| Frohlich, ED | 5 |
| Mehta, J | 1 |
| Mehta, P | 1 |
| Greenberg, S | 4 |
| Wilborn, WM | 1 |
| Beckenbauer, UE | 1 |
| Hoffmann, IS | 1 |
| Davila, J | 1 |
| Barbella, YR | 1 |
| Ordaz, P | 1 |
| Hamilton, BP | 1 |
| Mersey, JH | 1 |
| Hamilton, J | 1 |
| Kuzbida, G | 1 |
| Pavlis, R | 1 |
| Levinson, P | 1 |
| Gil-Ad, I | 1 |
| Gurewitz, R | 1 |
| Marcovici, O | 1 |
| Rosenfeld, J | 2 |
| Laron, Z | 1 |
| González Juanatey, JR | 1 |
| Reino, AP | 1 |
| Amaro Cendón, A | 1 |
| Rubio Alvarez, J | 1 |
| Fernández Iglesias, A | 1 |
| Gil de la Peña, M | 1 |
| Hess, RW | 3 |
| Taubert, KA | 3 |
| Brandt, D | 2 |
| Plänitz, V | 2 |
| Groth, H | 4 |
| Vetter, H | 4 |
| Knüsel, J | 4 |
| Foerster, E | 1 |
| Siegenthaler, W | 5 |
| Vetter, W | 5 |
| Goshima, Y | 1 |
| Ueda, H | 1 |
| Misu, Y | 1 |
| Falkner, B | 8 |
| Koffler, S | 1 |
| Lowenthal, DT | 9 |
| Algren, JT | 1 |
| Rodgers, GC | 1 |
| Masotti, G | 4 |
| Scarti, L | 4 |
| Poggesi, L | 3 |
| Bisi, G | 2 |
| Gallini, C | 2 |
| Neri Serneri, GG | 3 |
| Fuentes, JA | 3 |
| Borrell, J | 1 |
| Naranjo, JR | 3 |
| Höhler, H | 1 |
| Lorenz, S | 1 |
| Markov, M | 1 |
| Zheliazkov, D | 1 |
| Georgiev, N | 1 |
| Kolber-Postepska, B | 1 |
| Zebrowska-Lupina, I | 1 |
| Markiewicz, M | 1 |
| Kleinrok, Z | 1 |
| Fleming, SE | 1 |
| Horvath, JS | 4 |
| Korda, A | 3 |
| Boerlin, HJ | 2 |
| Walger, P | 2 |
| Baumgart, P | 3 |
| Wehling, M | 2 |
| Lian, QS | 1 |
| Lincová, D | 1 |
| Volkov, VS | 1 |
| Tsikulin, AE | 1 |
| Popli, S | 2 |
| Stroka, G | 1 |
| Ing, TS | 2 |
| Daugirdas, JT | 2 |
| Norusis, MJ | 1 |
| Hano, JE | 2 |
| Gandhi, VC | 1 |
| Pérez-Acuña, F | 1 |
| Monsalve, P | 2 |
| Pérez, J | 2 |
| Tremarias, A | 2 |
| Sanabria, A | 2 |
| Fragachán, F | 2 |
| Guthrie, GP | 4 |
| Miller, RE | 1 |
| Kotchen, TA | 3 |
| Koenig, SH | 1 |
| González-Gómez, A | 1 |
| Díaz Novás, J | 1 |
| Gamio Capestany, F | 1 |
| Rodríguez de la Vega, A | 1 |
| García-Barreto, D | 1 |
| Celuch, SM | 1 |
| Enero, MA | 1 |
| Zborovskiĭ, EI | 1 |
| Avramenko, TV | 1 |
| Kshirsagar, NA | 1 |
| Paul, T | 1 |
| Satoskar, RS | 1 |
| Russ, GR | 1 |
| Whitworth, JA | 3 |
| Kincaid-Smith, P | 4 |
| Galanti, G | 1 |
| Sciagrà, R | 2 |
| Okorokov, AN | 1 |
| Geĭman, EV | 1 |
| Lopez, LM | 3 |
| Mehta, JL | 3 |
| Cavero, I | 4 |
| Lefevre-Borg, F | 1 |
| Lhoste, F | 2 |
| Sabatier, C | 1 |
| Richer, C | 1 |
| Giudicelli, JF | 1 |
| Eninia, GI | 1 |
| Smeltere, ES | 1 |
| Godlevska, MA | 1 |
| Uzulinia, IP | 1 |
| Wibell, L | 1 |
| Puolakka, J | 1 |
| Kauppila, A | 1 |
| Vuori, J | 1 |
| Young, E | 1 |
| Levey, BA | 1 |
| Shapiro, AP | 2 |
| Hakala, M | 1 |
| Beitman, RE | 1 |
| Kuzma, RJ | 1 |
| Morledge, J | 1 |
| Mroczek, W | 1 |
| Rolf, CN | 1 |
| Tsai, TH | 1 |
| Massingham, R | 1 |
| Lefèvere-Borg, F | 1 |
| Bando, Y | 1 |
| Koike, Y | 5 |
| Shimamura, K | 5 |
| Saito, H | 4 |
| Kurosawa, M | 1 |
| Yasuda, H | 1 |
| Rodrigues, E | 1 |
| Lawson, AA | 3 |
| Nakagawa, Y | 1 |
| Takeda, K | 3 |
| Hashimoto, T | 1 |
| Sakurai, H | 1 |
| Mitomi, A | 1 |
| Imai, S | 1 |
| Hamamura, M | 1 |
| Kumada, M | 1 |
| Hitzenberger, G | 1 |
| Dorcsi, M | 1 |
| Bauer, P | 1 |
| Wohlzogen, FX | 1 |
| Foresti, A | 2 |
| Massari, FM | 2 |
| Moglia, F | 1 |
| Lotto, A | 2 |
| Antoszewski, Z | 1 |
| Bross, W | 1 |
| Wlodarski, JM | 1 |
| Khalfen, ESh | 1 |
| Dovgalevskiĭ, PIa | 1 |
| Korsh, BS | 1 |
| Pankova, GF | 1 |
| McGovern, BA | 1 |
| Bibracher, C | 1 |
| Podzich, M | 1 |
| Zweifler, A | 1 |
| Gross, M | 1 |
| Sisson, J | 1 |
| Mancia, G | 3 |
| Golub, MS | 3 |
| Thananopavarn, C | 3 |
| Eggena, P | 2 |
| Barrett, JD | 2 |
| Affrime, MB | 4 |
| Meyer, A | 1 |
| Kim, KE | 1 |
| Sharif, K | 2 |
| Arndts, D | 1 |
| Whitsett, TL | 4 |
| Spitalewitz, S | 1 |
| Porush, JG | 1 |
| Oguagha, C | 1 |
| Gray, DR | 2 |
| Onesti, G | 6 |
| Ferguson, RP | 1 |
| Alvino, E | 1 |
| Hamstra, B | 1 |
| Goldberg, MR | 2 |
| Hollister, AS | 2 |
| Wade, D | 1 |
| Robertson, RM | 2 |
| Whiting, B | 1 |
| Hui, KK | 1 |
| Artman, M | 1 |
| Boerth, RC | 1 |
| Zamotaev, IP | 1 |
| Abramova, VG | 1 |
| Stankovskaia, IM | 1 |
| Stiff, JL | 1 |
| Harris, DB | 1 |
| Battilana, G | 1 |
| Rigoni, A | 1 |
| Puppis, E | 1 |
| Carretta, R | 1 |
| Fabris, B | 1 |
| Tonutti, L | 1 |
| Velasquez, MT | 1 |
| Rho, J | 1 |
| Barr, J | 1 |
| Yagupsky, P | 1 |
| Gorodischer, R | 1 |
| Hair, TL | 1 |
| Graf, E | 1 |
| Doppelfeld, IS | 1 |
| Prop, G | 1 |
| Aigner, A | 1 |
| Schmidt, U | 1 |
| Akhmetova, BKh | 1 |
| Didenko, RG | 1 |
| Abdullina, RN | 1 |
| Davidenko, IuD | 1 |
| Rosenberg, JM | 1 |
| Kirschenbaum, HL | 1 |
| Hoffmann, WF | 1 |
| Ladogana, L | 1 |
| Witman, G | 1 |
| Davis, R | 1 |
| Zacest, R | 1 |
| Barrow, CG | 1 |
| O'Halloran, MW | 1 |
| Wilson, LL | 1 |
| O'Connor, DE | 1 |
| Lentini, S | 1 |
| Antonelli, S | 1 |
| Leone, G | 1 |
| Paoletti, V | 1 |
| Berkowitz, RL | 2 |
| Salvetti, A | 5 |
| Pedrinelli, R | 3 |
| Cavasinni, L | 1 |
| Simonini, N | 1 |
| Grossman, SH | 1 |
| Gunnells, JC | 1 |
| Gerber, JG | 1 |
| Freed, CR | 1 |
| Nies, AS | 2 |
| Abe, K | 2 |
| Otsuka, Y | 1 |
| Irokawa, N | 1 |
| Yasujima, M | 1 |
| Saito, K | 1 |
| Sakurai, Y | 1 |
| Chiba, S | 1 |
| Ito, T | 1 |
| Sato, M | 1 |
| Haruyama, T | 1 |
| Miura, Y | 2 |
| Yoshinaga, K | 1 |
| Schäfer, N | 1 |
| Rauh, J | 1 |
| Rosenthal, J | 3 |
| Jerie, P | 1 |
| Distler, A | 5 |
| Kirch, W | 2 |
| Lüth, B | 1 |
| Jäättelä, A | 1 |
| Lauro, R | 2 |
| Reda, G | 1 |
| Spallone, L | 1 |
| Anguissola, AB | 1 |
| Almazov, VA | 1 |
| Larikova, LP | 1 |
| Syrenskiĭ, AV | 1 |
| Temirov, AA | 1 |
| Segal, JL | 1 |
| Kluyskens, Y | 1 |
| Snoeck, J | 1 |
| Steger, W | 2 |
| Tsfasman, AZ | 1 |
| Zhuravleva, GN | 1 |
| Bronskiĭ, VI | 1 |
| Gaĭtsgori, ES | 1 |
| Sinaĭskaia, TN | 1 |
| Wetzels, E | 1 |
| Raschig, A | 1 |
| Kaiser, HJ | 1 |
| Miach, PJ | 1 |
| Cohen, IM | 4 |
| Stone, RA | 3 |
| Telfer, N | 1 |
| Weidmann, P | 1 |
| Yomaida, I | 4 |
| Barbieri, C | 3 |
| Caldara, R | 3 |
| Testori, G | 2 |
| Piepoli, V | 1 |
| Trezzi, R | 1 |
| Romussi, M | 1 |
| Ferrari, C | 3 |
| Hansson, BG | 2 |
| Kaplan, HR | 1 |
| Del Guercio, R | 1 |
| Gentile, S | 1 |
| Wilkins, LH | 1 |
| Winternitz, SR | 1 |
| Smith, LR | 1 |
| Dustan, HP | 2 |
| Hernández, E | 1 |
| Ramírez, A | 2 |
| Aliendres, R | 2 |
| Onida, L | 1 |
| Bonazzi, M | 1 |
| Dell'Aquila, F | 1 |
| Della Pietra, A | 1 |
| Maciel, RM | 1 |
| Spritzer, N | 1 |
| Spritzer, TS | 1 |
| Abichequer, MB | 1 |
| Gajendragadkar, SV | 1 |
| Schork, MA | 1 |
| Reisman, L | 1 |
| Selden, RV | 1 |
| Nghiem, C | 1 |
| Swamy, VC | 1 |
| Triggle, DJ | 1 |
| Virtanen, K | 1 |
| Jänne, J | 1 |
| Frick, MH | 1 |
| Fagan, TC | 2 |
| Bloomfield, SS | 1 |
| Corns-Hurwitz, RH | 1 |
| Lipicky, RJ | 1 |
| Hsu, CY | 1 |
| Grossman, WJ | 1 |
| Harmon, GE | 1 |
| Degenhart, WJ | 1 |
| Sinkfield, AW | 1 |
| Gaffney, TE | 1 |
| Dunn, FG | 1 |
| Messerli, FH | 1 |
| Dreslinski, GR | 1 |
| Caris, TN | 1 |
| Karppanen, H | 1 |
| Cumming, AM | 1 |
| Brown, JJ | 5 |
| Lever, AF | 5 |
| Robertson, JI | 5 |
| Tung, CS | 1 |
| Ring, M | 1 |
| Gerkens, JF | 1 |
| Burris, JF | 4 |
| D'Angelo, LJ | 1 |
| Moss, HB | 1 |
| Procci, WR | 1 |
| Shuba, TD | 1 |
| Ena, LM | 1 |
| Wilborn, W | 1 |
| Bundschu, HD | 1 |
| Kessler, G | 1 |
| Bischoff, K | 1 |
| Weh, L | 1 |
| Passa, P | 1 |
| Leblanc, H | 1 |
| Gauvillé, C | 1 |
| Tabuteau, F | 1 |
| Canivet, J | 1 |
| Collart, F | 1 |
| Medvedev, OS | 3 |
| Hayashi, T | 2 |
| Nakamura, K | 6 |
| Martens, V | 1 |
| Bentsen, P | 1 |
| Hochrein, H | 1 |
| Montini, M | 1 |
| Sileo, F | 1 |
| Moshang, T | 1 |
| Andrews-Figueroa, P | 1 |
| O'Donnell, A | 1 |
| Volicer, L | 1 |
| Crumpler, CP | 1 |
| Reed, WG | 2 |
| Matthews, CA | 1 |
| Faivre, JM | 1 |
| Freysz, M | 1 |
| Coulon, C | 1 |
| Jaboeuf, R | 1 |
| David, M | 1 |
| Danilov, LN | 1 |
| Turchetti, G | 1 |
| Di Veroli, C | 2 |
| Heinroth, I | 1 |
| Henrich, WL | 1 |
| Mitchell, H | 1 |
| Anderson, S | 2 |
| Cronin, R | 1 |
| Tollefson, GD | 1 |
| Luca, C | 1 |
| Graziani, G | 1 |
| Griffini, P | 1 |
| Hogan, MJ | 1 |
| Wallin, JD | 3 |
| Chu, LC | 1 |
| Val'dman, AV | 1 |
| Rozhanskaia, NI | 1 |
| Andréjak, M | 2 |
| Fievet, P | 1 |
| Makdassi, R | 1 |
| Comoy, E | 2 |
| De Fremont, JF | 2 |
| Coevoet, B | 2 |
| Fournier, A | 4 |
| Cellina, G | 1 |
| Lo Cicero, G | 1 |
| Montanari, C | 1 |
| Barbato, M | 1 |
| Brina, A | 1 |
| Middleton, RS | 1 |
| Esser, H | 1 |
| Kikis, D | 1 |
| Stumpe, KO | 6 |
| Krück, F | 1 |
| Curtarelli, G | 1 |
| Gavras, I | 2 |
| Gavras, H | 2 |
| Dal Bo, GA | 1 |
| Bertazzoni, A | 1 |
| Stevens, JE | 1 |
| Okada, T | 2 |
| Ishii, H | 2 |
| Elizur, A | 1 |
| Liberson, Z | 1 |
| Kushins, L | 1 |
| Buccafusco, JJ | 2 |
| Cybulska, I | 2 |
| Wasowska-Ciszek, T | 1 |
| Chen, YH | 1 |
| Chan, SH | 1 |
| Girardet, JP | 1 |
| Christensen, NJ | 3 |
| Brown, MJ | 2 |
| Salmon, D | 1 |
| Rendell, M | 1 |
| Noveck, RJ | 1 |
| Jain, AK | 3 |
| Ryan, JR | 3 |
| Svensson, TH | 2 |
| Almgren, O | 1 |
| Dahlöf, C | 2 |
| Elam, M | 2 |
| Engberg, G | 2 |
| Hallberg, H | 1 |
| Thorén, P | 1 |
| Pessina, AC | 4 |
| Hlede, M | 2 |
| Pigato, R | 3 |
| Palatini, P | 2 |
| Dal Palù, C | 2 |
| Rimatori, C | 1 |
| Russo, P | 1 |
| Melina, D | 1 |
| Guerrera, G | 1 |
| Traub, YM | 1 |
| Bender, F | 1 |
| Fouad, FM | 1 |
| Williams, H | 1 |
| Tarazi, RC | 3 |
| Tseng, CJ | 1 |
| Chen, SY | 1 |
| Tao, PL | 1 |
| Chern, JW | 1 |
| Yen, MH | 1 |
| Sattar, MA | 2 |
| Johns, EJ | 3 |
| Abdul Sattar, M | 1 |
| Rupp, H | 2 |
| Dhalla, KS | 1 |
| Dhalla, NS | 1 |
| Haxhiu, MA | 2 |
| Dreshaj, I | 2 |
| Schäfer, SG | 3 |
| Golusinski, LL | 1 |
| Blount, BW | 1 |
| Jiang, GC | 2 |
| Iwanov, V | 2 |
| Moulds, RF | 2 |
| Corazza, M | 1 |
| Mantovani, L | 1 |
| Virgili, A | 1 |
| Strumia, R | 1 |
| Cugurra, F | 1 |
| Naruse, T | 4 |
| Ishii, R | 4 |
| Tagawa, T | 4 |
| Panfilov, V | 1 |
| MacPhee, G | 1 |
| Puybasset, L | 1 |
| Lacolley, P | 2 |
| Laurent, S | 2 |
| Mignon, F | 1 |
| Billaud, E | 1 |
| Cuche, JL | 1 |
| Safar, M | 5 |
| Ivorra, D | 1 |
| Gascón, S | 1 |
| Vila, E | 1 |
| Badia, A | 1 |
| Jin, XQ | 1 |
| Chen, DG | 3 |
| Zhang, S | 2 |
| Wang, HJ | 2 |
| Danchin, N | 1 |
| Genton, P | 1 |
| Atlas, P | 1 |
| Anconina, J | 1 |
| Leclere, J | 1 |
| Cherrier, F | 1 |
| Minami, N | 1 |
| Casiglia, E | 2 |
| Spolaore, P | 1 |
| Mazza, A | 1 |
| Ginocchio, G | 1 |
| Colangeli, G | 1 |
| Onesto, C | 1 |
| Di Menza, G | 1 |
| Pegoraro, L | 1 |
| Ambrosio, GB | 1 |
| Ambrosioni, E | 4 |
| Kato, T | 1 |
| Noguchi, K | 1 |
| Sakanashi, M | 1 |
| Tanaka, M | 1 |
| Nishikawa, T | 1 |
| Prattichizzo, FA | 1 |
| Galetta, F | 1 |
| Bonechi, I | 1 |
| Giusti, C | 1 |
| He, B | 1 |
| Cervenka, JH | 1 |
| Parmer, RJ | 1 |
| Franco-Bourland, RE | 1 |
| Madrazo, I | 1 |
| Langlais, PJ | 1 |
| Lepage, JY | 1 |
| Pinaud, M | 3 |
| Hélias, J | 1 |
| Malinovsky, JM | 1 |
| Cozian, A | 1 |
| Petitet, A | 1 |
| Souron, R | 1 |
| Kamata, K | 1 |
| Numazawa, T | 1 |
| Kasuya, Y | 1 |
| Brown, JL | 1 |
| Sinding, H | 1 |
| Mathias, CJ | 10 |
| Tanaka, S | 1 |
| Tsuchida, H | 1 |
| Namba, H | 1 |
| Namiki, A | 1 |
| Xie, LD | 1 |
| Chen, HJ | 1 |
| Man, D | 1 |
| Graff, LM | 1 |
| Collins, LA | 1 |
| Grove, DL | 1 |
| Graves, ME | 1 |
| Christen, MO | 1 |
| Zoukos, Y | 1 |
| Thomaides, T | 1 |
| Chaudhuri, KR | 2 |
| Pavitt, DV | 1 |
| Cuzner, ML | 1 |
| Molderings, GJ | 1 |
| Göthert, M | 1 |
| Christen, O | 1 |
| Janssen, BJ | 2 |
| Oosting, J | 1 |
| Tyssen, CM | 2 |
| Struyker-Boudier, HA | 3 |
| Blanc, J | 1 |
| Grichois, ML | 1 |
| Vincent, M | 1 |
| Elghozi, JL | 4 |
| Guríanov, VA | 1 |
| Dolina, OA | 1 |
| Tiukov, VL | 1 |
| Bolśhakova, TD | 1 |
| Aliautdin, RN | 1 |
| Fazio, S | 1 |
| Sabatini, D | 1 |
| Cittadini, A | 1 |
| Santomauro, M | 1 |
| Merola, B | 1 |
| Biondi, B | 1 |
| Colao, A | 1 |
| Lombardi, G | 1 |
| Saccà, L | 1 |
| Gales, MA | 1 |
| Kolloch, RE | 1 |
| Mehlburger, L | 2 |
| Schumacher, H | 2 |
| Göbel, BO | 1 |
| Breidthardt, J | 1 |
| Gorbea-Oppliger, VJ | 1 |
| Fink, GD | 1 |
| Neĭko, IeM | 1 |
| Serediuk, NM | 1 |
| Orynchak, MA | 1 |
| Jastrzebski, Z | 2 |
| Goźlińska, B | 2 |
| Czyzewska-Szafran, H | 3 |
| Hays, L | 1 |
| Soltis, EE | 1 |
| Newman, PS | 1 |
| Trowbridge, JL | 1 |
| Zheng, X | 2 |
| Vincent, D | 1 |
| Pradalier, A | 1 |
| Dontenwill, M | 2 |
| Bricca, G | 2 |
| Fukuda, T | 1 |
| Dohi, S | 1 |
| Naito, H | 1 |
| Bhatia, RS | 1 |
| Lin, JC | 3 |
| Tsao, WL | 1 |
| Lee, HK | 1 |
| Wang, Y | 3 |
| Berg, PA | 1 |
| Hayashi, J | 2 |
| Kuwabara, T | 1 |
| Takesako, T | 1 |
| Itoh, H | 1 |
| Hirata, M | 1 |
| Tanabe, S | 1 |
| Nakata, T | 2 |
| Sasaki, S | 2 |
| Nakagawa, M | 2 |
| Netterville, JL | 1 |
| Mosqueda-Garcia, R | 4 |
| Munro, HM | 1 |
| Sleigh, JW | 1 |
| Paxton, LD | 1 |
| Reda, DJ | 4 |
| Massie, BM | 2 |
| Freis, ED | 3 |
| Kochar, MS | 1 |
| Hamburger, RJ | 1 |
| Fye, C | 1 |
| Lakshman, R | 1 |
| Gottdiener, J | 1 |
| Gulati, A | 1 |
| Arora, RC | 1 |
| Crayton, J | 1 |
| Lal, KJ | 2 |
| Dakshinamurti, K | 3 |
| Zhang, T | 1 |
| Ding, H | 1 |
| Wang, C | 1 |
| Wyss, JM | 8 |
| Mozaffari, MS | 3 |
| Roysommuti, S | 2 |
| Logunov, OV | 1 |
| Fitzgibbon, D | 1 |
| Rapp, S | 1 |
| Butler, S | 1 |
| Terman, G | 1 |
| Dolack, G | 1 |
| DuPen, S | 1 |
| Ready, LB | 1 |
| Beenen, OH | 3 |
| Pfaffendorf, M | 3 |
| Maisch, B | 1 |
| Brilla, CG | 1 |
| Tan, SA | 1 |
| Berk, LS | 1 |
| Tan, LG | 1 |
| Ishida, T | 2 |
| Agelink, MW | 1 |
| Dammers, S | 1 |
| Zeit, T | 1 |
| Blackman, JA | 1 |
| Samson-Fang, L | 1 |
| Gutgesell, H | 1 |
| Tokbaeva, KK | 1 |
| Zaslavskaia, RM | 2 |
| Khalberg, F | 1 |
| Teiblium, MM | 2 |
| Ely, D | 3 |
| Caplea, A | 2 |
| Dunphy, G | 2 |
| Daneshvar, H | 1 |
| Turner, M | 1 |
| Milsted, A | 2 |
| Takiyyudin, M | 1 |
| Luther, HP | 1 |
| Homuth, V | 1 |
| Wallukat, G | 1 |
| Friedman, JE | 1 |
| Koletsky, RJ | 1 |
| Namba, K | 1 |
| Guagnano, MT | 1 |
| Pace Palitti, V | 1 |
| Merlitti, D | 1 |
| Carrabs, C | 1 |
| Santucci, E | 1 |
| Sensi, S | 1 |
| Gottdiener, JS | 1 |
| Williams, DW | 2 |
| Tsushima, H | 1 |
| Fujimoto, S | 1 |
| Chaouche-Teyara, K | 2 |
| Challande, P | 1 |
| Fournier, B | 2 |
| Dabiré, H | 2 |
| Kawasaki, H | 4 |
| Liu, DM | 1 |
| Christensen, PK | 2 |
| Hansen, HP | 1 |
| Parving, HH | 3 |
| Iriuchijima, J | 3 |
| Satia, MC | 1 |
| Damani, RR | 1 |
| Goyal, RK | 1 |
| Guyenet, PG | 1 |
| Suraci, S | 1 |
| Giuditta, M | 1 |
| Mistò, M | 1 |
| Zanchetti, A | 4 |
| Hohage, H | 1 |
| Hess, K | 1 |
| Jahl, C | 1 |
| Greven, J | 1 |
| Schlatter, E | 1 |
| Cheng, CY | 1 |
| Wang, JY | 1 |
| Giugliano, D | 1 |
| Acampora, R | 1 |
| Marfella, R | 1 |
| La Marca, C | 1 |
| Marfella, M | 1 |
| Nappo, F | 1 |
| D'Onofrio, F | 1 |
| Xu, K | 1 |
| Lu, Z | 1 |
| Wei, H | 1 |
| Zhang, Y | 1 |
| Han, C | 1 |
| Sadchikov, DV | 1 |
| Eliutin, DV | 1 |
| Mil'tsyn, AS | 1 |
| Radev, R | 1 |
| Fior-Chadi, DR | 1 |
| Fuxe, K | 1 |
| Swartzman, LC | 1 |
| Burkell, J | 1 |
| Furuta, M | 1 |
| Hashimoto, M | 1 |
| Hata, T | 1 |
| Lenz, T | 2 |
| Ross, A | 1 |
| Schumm-Draeger, P | 1 |
| Schulte, KL | 2 |
| Geiger, H | 1 |
| Kunduzova, OR | 1 |
| Murashev, AN | 1 |
| Medvedeva, NA | 1 |
| Nurminen, ML | 1 |
| Culman, J | 1 |
| Haass, M | 1 |
| Chung, O | 1 |
| Unger, T | 2 |
| Holman, HE | 1 |
| Haas, RE | 1 |
| Pini, A | 1 |
| Clavario, P | 1 |
| Pedevilla, M | 1 |
| Airoldi, G | 1 |
| Copello, F | 1 |
| Massari, D | 1 |
| Martinengo, E | 1 |
| Trucco, U | 1 |
| De Martini, M | 1 |
| Lazzeri, C | 1 |
| La Villa, G | 1 |
| Mannelli, M | 2 |
| Janni, L | 1 |
| Barletta, G | 1 |
| Montano, N | 1 |
| Franchi, F | 1 |
| Kappagoda, C | 1 |
| Schell, DN | 1 |
| Hanson, RM | 1 |
| Hutchins, P | 1 |
| Mao, HZ | 1 |
| Babu, K | 1 |
| Marker, P | 1 |
| Rocchini, AJ | 1 |
| Parlow, JL | 2 |
| Bégou, G | 2 |
| Sagnard, P | 2 |
| Cottet-Emard, JM | 1 |
| Levron, JC | 1 |
| Annat, G | 1 |
| Bonnet, F | 1 |
| Ghignone, M | 3 |
| Hughson, R | 1 |
| Viale, JP | 2 |
| Lakshman, MR | 1 |
| Cline, JC | 1 |
| Connelly, J | 1 |
| Myles, PS | 1 |
| Hunt, JO | 1 |
| Holdgaard, HO | 1 |
| McRae, R | 1 |
| Buckland, MR | 1 |
| Moloney, J | 1 |
| Hall, J | 1 |
| Bujor, MA | 1 |
| Esmore, DS | 1 |
| Davis, BB | 1 |
| Morgan, DJ | 1 |
| Ejaz, AA | 1 |
| Meschia, JF | 1 |
| Baltodano, NM | 1 |
| Cienki, J | 1 |
| Kariya, N | 1 |
| Shindoh, M | 1 |
| Nishi, S | 1 |
| Yukioka, H | 1 |
| Asada, A | 1 |
| Drzewoski, J | 1 |
| Wiśniewska-Jarosińska, M | 1 |
| Schäfer, U | 1 |
| Raasch, W | 1 |
| Qadri, F | 1 |
| Chun, J | 1 |
| Dominiak, P | 1 |
| Peters, SL | 1 |
| Harris, SI | 1 |
| Alvarez, C | 1 |
| Dias, VC | 1 |
| Tendler, B | 1 |
| Reilly, PA | 1 |
| Snarr, P | 1 |
| White, WB | 2 |
| Mediavilla García, JD | 1 |
| López de la Torre Casares, M | 1 |
| Hidalgo Tenorio, C | 1 |
| Fernández-Torres, C | 1 |
| Aliaga Martínez, L | 1 |
| Peran Mesa, F | 1 |
| Muros de Fuentes, MA | 1 |
| Makino, Y | 1 |
| Kawano, Y | 1 |
| Okuda, N | 1 |
| Horio, T | 1 |
| Iwashima, Y | 1 |
| Yamada, N | 1 |
| Takamiya, M | 1 |
| Málek, J | 1 |
| Knor, J | 1 |
| Kurzová, A | 1 |
| Lopourová, M | 1 |
| Ianni, L | 1 |
| Cilotti, A | 1 |
| Conti, A | 1 |
| Robles, NR | 1 |
| Herman, M | 1 |
| Ely, L | 1 |
| Barrett, L | 1 |
| Roche, WJ | 1 |
| Nwofia, C | 1 |
| Gittler, M | 1 |
| Patel, R | 1 |
| Yarkony, G | 1 |
| Epstein, M | 2 |
| Prys-Roberts, C | 1 |
| Freedman, RR | 1 |
| Girgis, R | 1 |
| Ishize, S | 1 |
| Abo-Zena, RA | 1 |
| Bobek, MB | 1 |
| Dweik, RA | 1 |
| De Deyne, C | 1 |
| Struys, M | 1 |
| Heylen, R | 1 |
| De Jongh, R | 1 |
| Van der Laenen, M | 1 |
| Buyse, L | 1 |
| Deghislage, J | 1 |
| Rolly, G | 1 |
| Patel, C | 1 |
| Warren, BK | 1 |
| Schaffer, SW | 1 |
| Rahmani, MA | 2 |
| David, V | 1 |
| Huang, M | 1 |
| DeGray, G | 1 |
| Varon, J | 1 |
| Marik, PE | 1 |
| Gajjar, D | 1 |
| Egan, B | 1 |
| Curè, J | 1 |
| Rust, P | 1 |
| VanTassel, P | 1 |
| Patel, SJ | 1 |
| Edwards, N | 1 |
| Blyton, CM | 1 |
| Kesby, GJ | 1 |
| Wilcox, I | 1 |
| Sullivan, CE | 1 |
| Chamiot-Clerc, P | 1 |
| Safar, ME | 3 |
| Bichan, NA | 1 |
| Maslov, AP | 1 |
| Dodick, DW | 1 |
| Johnson, TR | 1 |
| Tobias, JD | 1 |
| Zawaideh, MA | 1 |
| Duncan, B | 1 |
| Joseph, MW | 1 |
| Dixit, MP | 1 |
| Seachrist, D | 1 |
| Vandelli, MA | 1 |
| Rivasi, F | 1 |
| Guerra, P | 1 |
| Forni, F | 1 |
| Arletti, R | 1 |
| Brahmbhatt, R | 1 |
| Baggaley, P | 1 |
| Hockings, B | 1 |
| Stefanadis, C | 1 |
| Manolis, A | 1 |
| Dernellis, J | 1 |
| Tsioufis, C | 1 |
| Tsiamis, E | 1 |
| Toutouzas, P | 1 |
| Lund, S | 1 |
| Girard, A | 1 |
| Ribstein, J | 1 |
| Szabo, B | 1 |
| Pelat, M | 1 |
| Verwaerde, P | 1 |
| Tran, MA | 2 |
| Montastruc, JL | 4 |
| Senard, JM | 1 |
| Bailey, RR | 3 |
| Neale, TJ | 1 |
| Scriabine, A | 2 |
| Clineschmidt, BV | 1 |
| Sweet, CS | 2 |
| Michel, D | 2 |
| Waal-Manning, HJ | 1 |
| Rosei, EA | 3 |
| Fraser, R | 1 |
| Morton, JJ | 1 |
| Trust, PM | 4 |
| McCombs, SK | 1 |
| Korner, PI | 1 |
| Blombery, PA | 1 |
| Tonkin, AM | 1 |
| Uther, JB | 1 |
| Goldberg, AD | 2 |
| Raftery, EB | 3 |
| Wilkinson, P | 1 |
| Rick, JH | 1 |
| Faulhaber, HD | 1 |
| Linss, G | 1 |
| Güllner, HG | 1 |
| Ludden, CT | 1 |
| Stavorski, JM | 1 |
| Wenger, HC | 1 |
| Bohidar, NR | 1 |
| Abdulla, W | 1 |
| Frey, R | 1 |
| Hardin, JM | 1 |
| Lambrey, G | 1 |
| Quichaud, J | 1 |
| Stokes, GS | 4 |
| Gain, JM | 2 |
| Mahony, JF | 1 |
| Raftos, J | 3 |
| Stewart, JH | 1 |
| Dadkar, NK | 3 |
| Dohadwalla, AN | 3 |
| Bhattacharya, BK | 1 |
| Redman, CW | 1 |
| Wollam, GL | 1 |
| Gifford, RW | 2 |
| Robson, RD | 1 |
| Antonaccio, MJ | 1 |
| Saelens, JK | 1 |
| Liebman, J | 1 |
| Klien, W | 1 |
| Bhagat, BD | 1 |
| Thomas, RD | 1 |
| Edmondson, RP | 1 |
| Hilton, PJ | 1 |
| Jones, NF | 1 |
| Pearson, RM | 1 |
| Havard, CW | 1 |
| Mancinella, A | 1 |
| Liuti, G | 1 |
| Paolucci, M | 1 |
| Baietti, M | 1 |
| Carletta, C | 1 |
| Röckel, A | 1 |
| Heidland, A | 1 |
| Kuchel, OG | 1 |
| Mahon, WA | 1 |
| McKenzie, JK | 1 |
| Ogilvie, RI | 1 |
| Hammond, JJ | 2 |
| Kirkendall, WM | 2 |
| Aroskar, VA | 1 |
| Israili, ZH | 1 |
| Yates, MS | 1 |
| Hiley, CR | 1 |
| Christersson, S | 1 |
| Meyer, P | 1 |
| Grünfeld, JP | 1 |
| Walters, WA | 1 |
| Palmer, GC | 1 |
| Caruso, G | 1 |
| Martello, G | 1 |
| Trovato, GM | 1 |
| Vancheri, FS | 1 |
| Enenkel, W | 1 |
| Birkenhäger, WH | 4 |
| Kho, TL | 3 |
| Kolsters, G | 1 |
| Schalekamp, MA | 3 |
| Wester, A | 3 |
| Zaal, GA | 3 |
| Rowe, WS | 1 |
| Wellens, D | 2 |
| Bogaert, A | 1 |
| DeWilde, A | 1 |
| Wouters, L | 1 |
| Bogaert, PP | 1 |
| Reneman, RS | 2 |
| Armbruster, H | 1 |
| Reck, G | 1 |
| Beckerhoff, R | 1 |
| Rosel, EA | 1 |
| Cairns, SA | 1 |
| Marshall, AJ | 1 |
| Dixon, GT | 1 |
| Johnson, ES | 1 |
| Harris, AL | 1 |
| Turner, P | 1 |
| Yudkin, JS | 2 |
| Wing, LM | 5 |
| Dargie, HJ | 2 |
| Hamilton, CA | 1 |
| Davies, DS | 4 |
| Dollery, CT | 10 |
| Reza, MJ | 1 |
| Atlas, SA | 2 |
| Sealey, JE | 2 |
| Laragh, JH | 4 |
| Moon, C | 1 |
| FitzGerald, G | 1 |
| Petrie, A | 1 |
| McDevitt, DG | 1 |
| Chilla, R | 1 |
| Arglebe, C | 1 |
| Montastruc, P | 3 |
| Moatti, JP | 1 |
| Atkinson, J | 3 |
| Boillat, N | 2 |
| Pera-Bally, R | 1 |
| Peters-Haefeli, L | 1 |
| Kirchertz, EJ | 1 |
| Kobinger, W | 1 |
| van Zwieten, AP | 1 |
| Langer, SZ | 2 |
| Metz, SA | 2 |
| Halter, JB | 2 |
| Porte, D | 2 |
| Robertson, RP | 2 |
| Finch, L | 3 |
| Buckingham, RE | 1 |
| Moore, RA | 1 |
| Bucher, TJ | 1 |
| Hedeland, H | 2 |
| Macdonald, IM | 1 |
| Hua, A | 1 |
| Laver, MC | 1 |
| Fang, P | 1 |
| Rotterdam, T | 1 |
| Mirouze, J | 1 |
| Monnier, L | 1 |
| Olivier, C | 1 |
| Smith, AJ | 1 |
| Romankiewicz, JA | 1 |
| Mancini, L | 1 |
| Squarcione, S | 1 |
| Fabbri, M | 1 |
| Fiorito, S | 1 |
| De Rugeriis, A | 1 |
| Castro, R | 1 |
| Graham, RM | 2 |
| Pistolese, GR | 1 |
| Agnoli, A | 1 |
| Prencipe, M | 1 |
| Pastore, E | 1 |
| Gossetti, B | 1 |
| Faraglia, V | 1 |
| Moses, C | 1 |
| Ben-Ishay, D | 1 |
| Zinger, M | 1 |
| Joffe, R | 1 |
| Steiner, S | 1 |
| Riddiough, MA | 1 |
| Shekhtman, MM | 1 |
| Volpin, EA | 1 |
| Turenko, AI | 1 |
| Zamanskaia, EM | 1 |
| Wilkinson, PR | 2 |
| Myers, MG | 2 |
| Fernandes, M | 2 |
| Bertoncini, H | 1 |
| Romero, E | 1 |
| Guevara, J | 4 |
| Pitkäjärvi, T | 3 |
| Kyöstilä, S | 1 |
| Kontro, J | 1 |
| Thomas, JC | 1 |
| Overturf, ML | 1 |
| Zama, A | 1 |
| Anshelevich, IuV | 2 |
| Raĭbart, IaIa | 2 |
| Panov, IP | 1 |
| Zveĭnietse, RA | 1 |
| Orshanskiĭ, EM | 1 |
| Ogino, K | 1 |
| Tomov, L | 1 |
| Tomov, I | 1 |
| Orbetsov, M | 1 |
| Todorova, M | 1 |
| Nikolov, G | 1 |
| Gantt, CL | 1 |
| Tschöpe, W | 1 |
| Orth, H | 1 |
| Ritz, E | 1 |
| Leary, WP | 1 |
| Asmal, AC | 1 |
| Williams, PC | 1 |
| Marvola, M | 1 |
| Seiler, AJ | 1 |
| Wood, RA | 1 |
| Karlberg, BE | 2 |
| Nilsson, O | 1 |
| Tolagen, K | 1 |
| Spach, MO | 1 |
| Steimer, C | 1 |
| Bloch, R | 1 |
| Wimmer, PP | 1 |
| Warren, SE | 1 |
| Ebert, E | 1 |
| Swerdlin, AH | 1 |
| Steinberg, SM | 1 |
| Stone, R | 1 |
| Allen, RM | 1 |
| Flemenbaum, A | 1 |
| Mashkovskiĭ, MD | 1 |
| Medvedev, BA | 1 |
| Erina, EV | 4 |
| Bunin, AIa | 1 |
| Ermakova, VN | 1 |
| Kaukinen, S | 2 |
| Kaukinen, L | 1 |
| Eerola, R | 1 |
| Hurley, DM | 1 |
| Vandongen, R | 1 |
| Beilin, LJ | 1 |
| Kuokkanen, K | 1 |
| Moreno-González, A | 1 |
| Vernon, C | 1 |
| Sakula, A | 1 |
| Engelman, K | 1 |
| Cocco, G | 1 |
| Strozzi, C | 1 |
| Haeusler, G | 2 |
| Chu, D | 1 |
| Amrein, R | 1 |
| Padovan, GC | 1 |
| Chrysant, SG | 3 |
| Geyskes, GG | 2 |
| Dorhout Mees, EJ | 2 |
| Boer, P | 2 |
| Keston, M | 1 |
| Yeung, CK | 1 |
| Thomas, GW | 1 |
| Männistö, PT | 1 |
| Kokkonen, J | 1 |
| Ranta, T | 1 |
| Murao, M | 1 |
| Monma, Y | 1 |
| Saito, HA | 1 |
| Stoll, C | 1 |
| Levy, JM | 1 |
| Beshara, D | 1 |
| Frankel, HL | 1 |
| Arena, G | 1 |
| Tedesco, V | 1 |
| Luque Otero, M | 1 |
| Fernández Pinilla, C | 1 |
| de la Fuente, A | 1 |
| Fernández Cruz, A | 2 |
| Gupte, RD | 1 |
| Caldari, R | 1 |
| Costa, FV | 1 |
| Magnani, B | 3 |
| Fénard, S | 2 |
| Lefevre, F | 1 |
| Roach, A | 1 |
| Otani, T | 1 |
| Kibler, LE | 1 |
| Gazes, PC | 1 |
| Ala-Laurila, P | 2 |
| Ruosteenoja, R | 2 |
| Torsti, P | 2 |
| Masar, SE | 1 |
| Neill, EA | 1 |
| Tippett, P | 1 |
| Basishvili, NZ | 1 |
| Castillo Higueras, PL | 1 |
| Rodríguez Cuartero, A | 1 |
| Rodríguez Cuartero, F | 1 |
| Urbano Jiménez, F | 1 |
| Peláez Redondo, J | 1 |
| Rahn, KH | 2 |
| Gadgil, UG | 2 |
| Sunavalla, JD | 1 |
| Pinto, IJ | 2 |
| Sheth, UK | 1 |
| De Thomatis, M | 1 |
| Montevecchi, A | 1 |
| Gallesio, R | 1 |
| Falciola, N | 1 |
| Ferrari, A | 1 |
| Gregorini, L | 1 |
| Ferrari, M | 1 |
| Parati, G | 2 |
| Spotnitz, HM | 1 |
| Heilmann, L | 1 |
| Kurz, E | 1 |
| Niarchos, AP | 3 |
| Bock, KD | 3 |
| Saran, RK | 1 |
| Sahuja, RC | 1 |
| Gupta, NN | 1 |
| Kishor, K | 1 |
| Ylitalo, P | 1 |
| Sweet, RM | 1 |
| Danielson, BD | 1 |
| Wathen, RL | 1 |
| Husserl, FE | 1 |
| deCarvalho, JG | 1 |
| Batson, HM | 1 |
| Scheinman, MM | 1 |
| Strauss, HC | 1 |
| Evans, GT | 1 |
| Ryan, C | 2 |
| Massie, B | 1 |
| Wallace, A | 1 |
| Katz, MA | 1 |
| Abiuso, P | 1 |
| Abelow, G | 1 |
| Charnaia, ES | 1 |
| Dillard, BL | 1 |
| Anton, AH | 1 |
| Pershakova, LP | 2 |
| Elizarova, NA | 1 |
| Beliakova, EV | 1 |
| Smirnova, TV | 1 |
| Edlund, PO | 1 |
| Sandifer, MG | 1 |
| Nigro, R | 1 |
| Tiraboschi, R | 1 |
| Caramuta, U | 1 |
| Branchini, B | 1 |
| Baer, L | 2 |
| Radichevich, I | 1 |
| Juskevich, JC | 1 |
| Robinson, DS | 1 |
| Whitehorn, D | 1 |
| Bhandarkar, SD | 1 |
| Vernekar, KS | 1 |
| Kissin, E | 1 |
| Teicher, A | 1 |
| Stern, N | 1 |
| Gallardo, E | 2 |
| Plaja, J | 2 |
| Todesco, S | 3 |
| Huber, W | 2 |
| Gambari, PF | 2 |
| Guardini, R | 2 |
| Glorioso, S | 2 |
| Antonello, A | 2 |
| Borsatti, A | 3 |
| Genest, J | 1 |
| Kuchel, O | 1 |
| Petrucci, D | 1 |
| Bianchi, G | 1 |
| Bielli, M | 1 |
| Romeo, PB | 1 |
| Vitolo, E | 1 |
| Folli, G | 1 |
| Henning, M | 1 |
| Maggiore, Q | 1 |
| Biagini, M | 1 |
| Zoccali, C | 1 |
| Misefari, M | 1 |
| Weiss, YA | 2 |
| Corvol, PL | 1 |
| Menard, JE | 1 |
| London, GM | 1 |
| Milliez, PL | 1 |
| Mroczek, WJ | 3 |
| Lee, WR | 1 |
| Davidov, ME | 1 |
| Perez, L | 1 |
| Peracha, MA | 1 |
| Ahmad, R | 1 |
| Saeed, M | 1 |
| Ilyas, M | 1 |
| Bertilsson, L | 1 |
| Haglund, K | 1 |
| Ostman, J | 1 |
| Rawlins, MD | 1 |
| Ringberger, VA | 1 |
| Sjöqvist, F | 1 |
| Lazzarin, M | 1 |
| Ferrari, S | 1 |
| Brym, E | 1 |
| Wolyńczyk-Niegowska, J | 1 |
| Sznajderman, M | 1 |
| Vargas, R | 1 |
| Haas, Th | 1 |
| Denkl, P | 1 |
| Grenfell, RF | 1 |
| Grissom, RL | 1 |
| Gust, WF | 1 |
| Hoobler, SW | 4 |
| Kashima, T | 1 |
| Storm-Mathisen, H | 3 |
| Tilson, HA | 1 |
| Chamberlain, JH | 1 |
| Gylys, JA | 1 |
| Buyniski, JP | 1 |
| England, JF | 1 |
| Heimsoth, VH | 1 |
| Velly, J | 1 |
| Bloch, RB | 1 |
| Schwartz, J | 2 |
| Roland, EQ | 1 |
| Lelguen, CE | 1 |
| Aboras, NE | 1 |
| Milliez, PM | 1 |
| Gessler, U | 1 |
| Pilgrim, R | 1 |
| Basu, J | 1 |
| Chakrabarty, K | 1 |
| Majumder, G | 1 |
| Neelakantan, C | 1 |
| Maity, AK | 1 |
| Bardhan, AK | 1 |
| Das, S | 1 |
| Ghosh, JC | 1 |
| Chhetri, MK | 1 |
| Engelking, H | 1 |
| Plaza de los Reyes, M | 1 |
| Lazcano, F | 1 |
| Orozco, R | 1 |
| Osorio, I | 1 |
| Passalaqua, W | 1 |
| Marzullo, E | 1 |
| Campino, C | 1 |
| Pla, C | 1 |
| Casado, S | 1 |
| Liaño, F | 1 |
| Hernando, L | 1 |
| Sugimoto, S | 2 |
| Hashida, M | 2 |
| Kasahara, K | 2 |
| Zweifler, AJ | 1 |
| Mottet, MM | 1 |
| Francis, GS | 1 |
| Alpert, JS | 1 |
| Dillard, B | 1 |
| Czerwinski, AW | 1 |
| Campanini, M | 1 |
| Kocemba, J | 1 |
| Kawecka-Jaszcz, K | 1 |
| Frolich, JC | 2 |
| Robertson, AS | 2 |
| Case, DB | 1 |
| Lopez-Overjero, JA | 1 |
| De Wurstemberger, B | 1 |
| Gysling, E | 1 |
| Cottier, P | 1 |
| Seiler, A | 1 |
| Zozulia, IS | 1 |
| Deusheva, RI | 1 |
| Angelino, PF | 1 |
| Lavezzaro, G | 1 |
| Sunawala, JD | 1 |
| Noronha, JL | 1 |
| Bhatia, ML | 1 |
| Gulati, PD | 1 |
| Rizvi, SN | 1 |
| Ballal, C | 1 |
| Saigal, H | 1 |
| Vaishnava, H | 1 |
| Rondelli, E | 1 |
| Biale, A | 1 |
| Gatti, C | 1 |
| Ghersi, G | 1 |
| Stella, G | 1 |
| Castelluccio, A | 1 |
| Bostock, MI | 1 |
| Wolkerstorfer, H | 1 |
| Agosta, R | 1 |
| Racco, F | 1 |
| Werner, U | 1 |
| Günnewig, H | 1 |
| Datey, KK | 2 |
| Simpson, FO | 3 |
| Gottlieb, TB | 1 |
| Chidsey, CA | 1 |
| Tarsy, D | 1 |
| Parkes, JD | 1 |
| Marsden, CD | 1 |
| Lavin, P | 1 |
| Alexander, CP | 1 |
| Kurppa, K | 1 |
| Huuskonen, M | 1 |
| Snoeckx, L | 1 |
| De Reese, R | 1 |
| Kruger, R | 1 |
| Van de Water, A | 1 |
| Woutens, L | 1 |
| Singh, N | 1 |
| Menon, V | 1 |
| Rosenman, RH | 1 |
| Kosman, ME | 1 |
| Hunyor, SN | 4 |
| Bradstock, K | 1 |
| Somerville, PJ | 1 |
| Lucas, N | 1 |
| Pals, DT | 1 |
| Bhagat, SJ | 1 |
| Goyal, BK | 1 |
| Mishra, SJ | 1 |
| Kapadia, NM | 1 |
| Rajlaxmi, BN | 1 |
| Staneva-Stoytcheva, D | 1 |
| Rainova, L | 1 |
| Georgieva, A | 1 |
| Cosnier, D | 2 |
| Duchene-Marullaz, P | 1 |
| Grimal, J | 1 |
| Rispat, G | 2 |
| Streichenberger, G | 2 |
| Labrid, C | 1 |
| Bear, R | 1 |
| Steer, K | 1 |
| Mundy, GR | 1 |
| Raisz, LG | 1 |
| Saarimaa, H | 1 |
| Meurer, KA | 1 |
| Kloos, G | 1 |
| Helber, A | 2 |
| Kaufmann, W | 2 |
| Stelzer, FP | 1 |
| Stubebbord, JJ | 1 |
| Screenivasan, V | 1 |
| Venuto, RC | 1 |
| Kozlovskiĭ, VI | 1 |
| Khulup, GIa | 1 |
| Koshelapov, VI | 1 |
| Atlas, D | 2 |
| Diamant, S | 2 |
| Zonnenschein, R | 1 |
| Reisin, E | 1 |
| Weed, SG | 1 |
| Nakamura, S | 2 |
| Takasaki, K | 3 |
| Runikhin, AIu | 1 |
| Krasnikova, TL | 1 |
| Minchuna, VP | 1 |
| Mazaev, AV | 1 |
| Feldman, J | 2 |
| Greney, H | 1 |
| Stutzmann, J | 1 |
| Belcourt, A | 1 |
| Maione, S | 1 |
| Vitagliano, S | 1 |
| Berrino, L | 1 |
| Lampa, E | 1 |
| Rossi, F | 2 |
| Mangroo, T | 1 |
| Bienaime, M | 1 |
| Wiggins, S | 1 |
| Williams, J | 1 |
| Radin, MJ | 1 |
| Jenkins, JE | 1 |
| McCune, SA | 1 |
| Jurin, RR | 1 |
| Hamlin, RL | 1 |
| Thiede, HM | 2 |
| Nussberger, J | 4 |
| Uza, G | 2 |
| Favazza, A | 1 |
| Motanaro, D | 1 |
| Messa, P | 1 |
| Antonucci, F | 1 |
| Gropuzzo, M | 1 |
| Mioni, G | 1 |
| Veber, VR | 1 |
| Kolodina, EA | 1 |
| Kerimkulova, AS | 1 |
| Kazymov, MS | 1 |
| Chadha, R | 1 |
| Padmanabhan, V | 1 |
| Joseph, A | 1 |
| Mohandas, K | 1 |
| Di Mario, U | 1 |
| Bacci, S | 1 |
| Morano, S | 1 |
| Pugliese, G | 1 |
| Pietravalle, P | 1 |
| Andreani, D | 1 |
| Morabito, S | 1 |
| Simonetti, B | 1 |
| Pierucci, A | 1 |
| Jonsson, O | 1 |
| Widmark, A | 1 |
| Grankvist, K | 1 |
| Damber, JE | 1 |
| Henriksson, R | 1 |
| Howes, LG | 3 |
| Remiszewska, M | 1 |
| Wutkiewicz, M | 1 |
| Poncet, MF | 1 |
| Tavernier, G | 1 |
| Damase-Michel, C | 1 |
| Berlan, M | 1 |
| Olmos, G | 1 |
| Miralles, A | 1 |
| Barturen, F | 1 |
| García-Sevilla, JA | 1 |
| Zeng, K | 1 |
| Clark, DW | 1 |
| Curzio, JL | 1 |
| Howie, CA | 1 |
| Laude, D | 1 |
| Janvier, F | 1 |
| Atkin, SH | 1 |
| Jaker, MA | 1 |
| Beaty, P | 1 |
| Quadrel, MA | 1 |
| Cuffie, C | 1 |
| Soto-Greene, ML | 1 |
| Barkin, RL | 1 |
| Stein, ZL | 1 |
| Alföldi, A | 1 |
| Simkó, K | 1 |
| Fekete, MI | 1 |
| Mitrovic, V | 5 |
| Patyna, W | 2 |
| von Bruchhausen, V | 3 |
| Schlepper, M | 3 |
| Baron, A | 1 |
| Riesselmann, A | 1 |
| Fregly, MJ | 1 |
| Mellina, IM | 1 |
| Tarakhovskiĭ, ML | 1 |
| Gutman, LB | 1 |
| Zaĭtseva, NE | 1 |
| Smits, JF | 1 |
| Pavlov, AA | 1 |
| Rykin, BA | 1 |
| Dubitskiĭ, AE | 1 |
| Lisniak, DK | 1 |
| Globa, IV | 1 |
| Riabov, IV | 1 |
| Gurgenian, SV | 1 |
| Mikaelian, ES | 1 |
| Dzhandzhapanian, AZ | 1 |
| Babaian, AS | 1 |
| Eerdmans, PH | 1 |
| Struyker Boudier, HA | 1 |
| De Mey, JG | 1 |
| Thomaides, TN | 1 |
| Ito, MK | 1 |
| Da Settimo, A | 1 |
| Marini, AM | 1 |
| Primofiore, G | 1 |
| Subissi, A | 1 |
| Papademetriou, V | 1 |
| Cook, ME | 1 |
| Weidler, DJ | 1 |
| Branche, GC | 1 |
| Batts, JM | 1 |
| Dowdy, VM | 1 |
| Field, LS | 1 |
| Francis, CK | 1 |
| Oster, JR | 1 |
| Dondici Filho, J | 1 |
| Gomes, JC | 1 |
| de Castro, EG | 1 |
| Luz, NS | 1 |
| Abzaid, A | 1 |
| Shishkina, GT | 1 |
| Markel', AL | 1 |
| Naumenko, EV | 1 |
| Hüting, J | 2 |
| Jin, HK | 6 |
| Yang, RH | 6 |
| Chen, YF | 5 |
| Catania, A | 1 |
| Baldini, M | 1 |
| Orsatti, A | 1 |
| Airaghi, L | 1 |
| Gasparini, P | 1 |
| Cantalamessa, L | 1 |
| Sclar, DA | 2 |
| Skaer, TL | 2 |
| Chin, A | 2 |
| Okamoto, MP | 2 |
| Gill, MA | 2 |
| Matney, J | 1 |
| Appalsamy, M | 1 |
| Sarna, S | 1 |
| Sternon, J | 1 |
| Tingley, FD | 1 |
| Arnerić, SP | 1 |
| Grosse, A | 1 |
| Bianchi, JM | 1 |
| Díaz Puertas de Grosse, CS | 1 |
| Iglesias, GE | 1 |
| Coviello, A | 1 |
| Berge, KH | 1 |
| Lanier, WL | 1 |
| Just, VL | 1 |
| Schrader, BJ | 1 |
| Paloucek, FP | 1 |
| Hoon, TJ | 1 |
| Leikin, JB | 1 |
| Bauman, JL | 1 |
| Phippard, AF | 1 |
| Fischer, WE | 1 |
| Child, AG | 1 |
| Korda, AR | 1 |
| Henderson-Smart, D | 2 |
| Duggin, GG | 2 |
| Tiller, DJ | 3 |
| Thormann, J | 1 |
| Bahavar, H | 1 |
| Goldstein, DS | 4 |
| Hoffman, A | 1 |
| Keiser, HR | 3 |
| Gretler, DD | 2 |
| Gramelspacher, GP | 1 |
| Fumo, MT | 1 |
| Elliott, WJ | 1 |
| Murphy, MB | 2 |
| Orlov, VM | 2 |
| Kolesova, MA | 2 |
| Sivkov, SI | 1 |
| Panchenkova, LA | 1 |
| Bachmann, AW | 2 |
| Gordon, RD | 3 |
| Atzeni, V | 1 |
| Maccioni, G | 1 |
| Fiorenza, M | 1 |
| Bernasconi, M | 1 |
| Beni, M | 1 |
| Chojnowski, K | 2 |
| Feltynowski, T | 2 |
| Lazecki, D | 2 |
| Bar-Andziak, E | 1 |
| Ignatowska-Switalska, H | 1 |
| Wocial, B | 2 |
| Moiseev, VS | 4 |
| Ivleva, AIa | 4 |
| Kobalava, ZhD | 2 |
| Lepakhin, VK | 1 |
| Graefe, KH | 1 |
| Halbrügge, T | 1 |
| Gerlich, M | 1 |
| Ludwig, J | 1 |
| Hess, W | 1 |
| Poliak, M | 1 |
| Horký, K | 1 |
| Kopecká, J | 1 |
| Gregorová, I | 1 |
| Dvoráková, J | 1 |
| Rudzite, VK | 1 |
| Vitols, AV | 2 |
| Liepinja, DJ | 1 |
| Silava, AK | 1 |
| Bouhelal, R | 1 |
| Loubatières-Mariani, MM | 1 |
| Mir, AK | 1 |
| Okajima, H | 1 |
| Kawasaki, S | 1 |
| Oguro, M | 1 |
| Viswanathan, M | 2 |
| Paulose, CS | 2 |
| Sharma, SK | 1 |
| Barletta, C | 1 |
| Scavo, D | 1 |
| Giustina, A | 1 |
| Doga, M | 1 |
| Bossoni, S | 1 |
| Bodini, C | 1 |
| Legati, F | 1 |
| Pizzocolo, G | 1 |
| Romanelli, G | 1 |
| Bernard, JM | 2 |
| Burger, C | 1 |
| Hays, JT | 1 |
| Nadeau, J | 1 |
| Swift, L | 1 |
| Bradley, CA | 1 |
| Olafsson, L | 1 |
| Vignali, G | 1 |
| Guadagnucci, A | 1 |
| Tulli, G | 1 |
| Kostis, JB | 1 |
| Rosen, RC | 1 |
| Holzer, BC | 1 |
| Randolph, C | 1 |
| Taska, LS | 1 |
| Miller, MH | 1 |
| Popiliev, I | 1 |
| Angelova, I | 2 |
| Kundurdzhiev, A | 1 |
| Kraft, K | 5 |
| Kokorsch, F | 2 |
| Diehl, J | 2 |
| Kolloch, R | 4 |
| Sauter, ER | 1 |
| Bakris, GL | 1 |
| Takeshita, E | 1 |
| Hayashi, S | 1 |
| Takenaka, T | 1 |
| Murakami, M | 1 |
| Saruta, T | 1 |
| Nagano, S | 1 |
| Sekihara, T | 1 |
| Zanozdra, LN | 1 |
| Skarda, IJ | 1 |
| Liepinia, DJ | 1 |
| Voita, DU | 1 |
| Skards, JV | 1 |
| Greene, CS | 1 |
| Cervenka, K | 1 |
| McCoy, CE | 1 |
| Brown, FD | 1 |
| Goldberg, M | 1 |
| Gehr, M | 1 |
| Hallier, E | 2 |
| Kuschke, HJ | 2 |
| Velandia Arevalo, J | 1 |
| Sharma, PL | 1 |
| Pandhi, P | 1 |
| Glezer, GA | 1 |
| Porotikov, VI | 1 |
| Terekhina, AI | 1 |
| Meĭler, SM | 1 |
| Cherenshchikova, EI | 1 |
| Jeunemaitre, X | 1 |
| Ged, E | 1 |
| Ducrocq, MB | 1 |
| McNeil, JJ | 1 |
| Workman, B | 1 |
| Drummer, OH | 1 |
| Ferder, L | 1 |
| Inserra, F | 1 |
| Medina, F | 1 |
| Chodakowska, J | 1 |
| Januszewicz, W | 1 |
| Mohanty, PK | 1 |
| Sowers, JR | 1 |
| McNamara, C | 1 |
| Thames, MD | 1 |
| Lewis, SJ | 1 |
| Maccarrone, C | 1 |
| Shulkes, A | 1 |
| Timio, M | 1 |
| Venanzi, S | 1 |
| Gentili, S | 1 |
| Ronconi, M | 1 |
| Del Re, G | 1 |
| Del Vita, M | 2 |
| Theobald, R | 2 |
| Schulte, W | 4 |
| Rüddel, H | 4 |
| Schmieder, R | 2 |
| von Eiff, AW | 1 |
| Kleine, P | 1 |
| Meissner, E | 1 |
| Brückner, S | 2 |
| Pomidossi, G | 1 |
| Malaspina, D | 1 |
| Colombo, A | 1 |
| Camesasca, C | 1 |
| Groppelli, A | 1 |
| Casadei, R | 1 |
| Hoffman, IS | 1 |
| Santarosa, RP | 1 |
| Larrabee, PS | 1 |
| Smith, RJ | 1 |
| Kallay, MC | 1 |
| Baranowska, B | 2 |
| Franklin, SS | 1 |
| Tonkon, MJ | 1 |
| Kirschenbaum, MA | 1 |
| Dobak, JD | 1 |
| Späh, F | 1 |
| Grosser, KD | 1 |
| Rüttimann, S | 1 |
| Noll, G | 1 |
| Schneider, K | 1 |
| Yamada, S | 1 |
| Ashizawa, N | 1 |
| Nakayama, K | 1 |
| Tomita, T | 1 |
| Hayashi, E | 1 |
| Klepzig, M | 1 |
| Holdiness, MR | 1 |
| Bernardin, M | 1 |
| Dorey, F | 1 |
| Louvel, A | 1 |
| Fouchard, J | 1 |
| Chapuis, Y | 1 |
| Luton, JP | 1 |
| Davies, SF | 1 |
| Graif, JL | 1 |
| Husebye, DG | 1 |
| Maddy, MM | 1 |
| McArthur, CD | 1 |
| Path, MJ | 1 |
| O'Connell, MB | 1 |
| Iber, C | 1 |
| Davidman, M | 1 |
| van Giersbergen, PL | 1 |
| Tierney, SA | 1 |
| Wiegant, VM | 1 |
| de Jong, W | 2 |
| Weder, AB | 1 |
| Takiyyuddin, M | 1 |
| Sekkarie, MA | 1 |
| Schmieder, RE | 2 |
| Bähr, M | 2 |
| Langewitz, W | 3 |
| Schächinger, H | 1 |
| Spence, CD | 1 |
| Mathai, M | 1 |
| Mills, EH | 1 |
| Coghlan, JP | 1 |
| Scoggins, BA | 1 |
| van den Buuse, M | 1 |
| Dinh Xuan, AT | 1 |
| Lockhart, A | 1 |
| Grimberg, D | 1 |
| Tarrade, T | 1 |
| Deschamps de Paillette, E | 1 |
| Söderpalm, B | 2 |
| Goldberg, ME | 1 |
| Seltzer, JL | 1 |
| Azad, SS | 1 |
| Smullens, SN | 1 |
| Marr, AT | 1 |
| Larijani, GE | 1 |
| Erard, PY | 1 |
| Gardaz, JP | 1 |
| Livio, JJ | 1 |
| Waeber, B | 3 |
| Brunner, HR | 4 |
| Freeman, J | 1 |
| Koshida, H | 1 |
| Miyamori, I | 1 |
| Takasaki, H | 1 |
| Takeda, R | 1 |
| Brown, J | 1 |
| Branche, G | 1 |
| Streets, M | 1 |
| King, A | 1 |
| Dowdy, V | 1 |
| Batts, J | 1 |
| de Leonardis, V | 1 |
| de Scalzi, M | 1 |
| Becucci, A | 1 |
| Lusini, C | 1 |
| Cinelli, P | 1 |
| Wasilewska-Dziubińska, E | 1 |
| Staff-Zielińska, E | 1 |
| Marabini, M | 1 |
| Aghemo, A | 1 |
| Thomas, JR | 1 |
| Fisher, SG | 1 |
| Borreson, RE | 1 |
| Mezey, KC | 1 |
| Mukherji, B | 1 |
| Neal, WW | 1 |
| Perry, HM | 1 |
| Taguchi, JT | 1 |
| Van Loon, GR | 1 |
| Wilcox, CS | 1 |
| Smith, TB | 1 |
| Frederickson, ED | 1 |
| Wingo, CD | 1 |
| Phillips, MI | 1 |
| Williams, CM | 1 |
| Vasků, J | 2 |
| Cerný, J | 1 |
| Dostál, M | 1 |
| Dolezel, S | 1 |
| Vasků, A | 1 |
| Guba, P | 1 |
| Urbánek, P | 1 |
| Petrzilka, J | 1 |
| Sotolová, O | 1 |
| Dichtchekenian, V | 1 |
| Sequeira, DM | 1 |
| Andriollo, A | 1 |
| Marcondes, M | 1 |
| Heimann, JC | 1 |
| Mejia, A | 1 |
| Kooner, JS | 2 |
| Peart, WS | 1 |
| Zeller, KR | 1 |
| Von Kuhnert, L | 1 |
| Matthews, C | 1 |
| Boutroy, MJ | 1 |
| Neusy, AJ | 1 |
| Schmidt, GR | 2 |
| Schuna, AA | 2 |
| Goodfriend, TL | 1 |
| Syrjanen, M | 1 |
| Hawkins, PG | 1 |
| Jensen, RA | 1 |
| Williams, L | 2 |
| Zeigler, DW | 1 |
| Kauker, ML | 1 |
| Kreisberg, GA | 1 |
| Diamant, YZ | 1 |
| Fritschka, E | 1 |
| Kribben, A | 1 |
| Hoyer, J | 1 |
| Rothschild, M | 1 |
| Philipp, T | 2 |
| Meng, QC | 1 |
| Sato, T | 1 |
| Igarashi, N | 1 |
| Minami, S | 1 |
| Okabe, T | 1 |
| Hasui, M | 1 |
| Kato, E | 1 |
| Rhee, HM | 1 |
| De Lapp, JD | 1 |
| Słowinska-Srzednicka, J | 2 |
| Zgliczynski, S | 2 |
| Soszynski, P | 2 |
| Puciłowska, J | 1 |
| Wierzbicki, M | 2 |
| Jeske, W | 2 |
| Valvo, E | 1 |
| Man in't Veld, AJ | 1 |
| Sidorenko, GI | 1 |
| Pavlova, AI | 1 |
| Nechesova, TA | 1 |
| Al'khimovich, VM | 1 |
| Gaĭduk, VN | 1 |
| Chervenak, FA | 1 |
| Vanholder, R | 2 |
| Lameire, N | 1 |
| Ringoir, S | 2 |
| Gradin, K | 2 |
| Persson, B | 2 |
| Brater, DC | 1 |
| Grabensee, B | 1 |
| Koĭchev, A | 1 |
| Belovezhdov, N | 2 |
| Chakŭrski, I | 1 |
| Stefanov, G | 1 |
| Dick, JB | 1 |
| Northridge, DB | 1 |
| Marx, BE | 1 |
| Baines, AD | 1 |
| Fillastre, JP | 1 |
| Letac, B | 1 |
| Galinier, F | 1 |
| Le Bihan, G | 1 |
| Stieglitz, P | 1 |
| Roden, DM | 1 |
| Nadeau, JH | 1 |
| Primm, RK | 2 |
| Gava, R | 1 |
| Giacomello, M | 1 |
| Cima, L | 1 |
| Giusti, P | 1 |
| Lamiere, N | 1 |
| Kapliev, VA | 1 |
| Ferguson, RK | 2 |
| Vlasses, PH | 2 |
| Jaker, M | 1 |
| Atkin, S | 1 |
| Soto, M | 1 |
| Schmid, G | 1 |
| Brosch, F | 1 |
| Levin, ER | 2 |
| Sharp, B | 2 |
| Lorrain, J | 1 |
| Di Paola, ED | 1 |
| Payen, B | 1 |
| Dennis, T | 2 |
| Scatton, B | 2 |
| Eskay, R | 1 |
| Zamir, N | 1 |
| Palkovits, M | 1 |
| Hollifield, J | 1 |
| Tunny, TJ | 1 |
| Klemm, SA | 1 |
| Akopian, LM | 2 |
| Krasnobaeva, GM | 3 |
| Basem, AS | 1 |
| Auffray, JP | 1 |
| Valli, M | 1 |
| Lancon, C | 1 |
| Alaya, M | 1 |
| Borsarelli, J | 1 |
| Kellaway, GS | 2 |
| Marini, M | 1 |
| Cavani, E | 1 |
| Abbatangelo, R | 1 |
| Mascelloni, R | 1 |
| Nakajima, T | 1 |
| Sato, Y | 1 |
| Fujita, T | 1 |
| Yasunari, K | 2 |
| Kanayama, Y | 2 |
| Kohno, M | 2 |
| Murakawa, K | 1 |
| Kawarabayashi, T | 1 |
| Takeda, T | 2 |
| Kotsugai, N | 2 |
| Sato, K | 3 |
| Koepke, JP | 1 |
| DiBona, GF | 1 |
| Szmigielski, A | 1 |
| Szadowska, A | 1 |
| Szmigielska, H | 1 |
| Starke, K | 1 |
| Peart, S | 4 |
| da Costa, DF | 1 |
| Cleary, JC | 1 |
| Bouvier, M | 1 |
| de Champlain, J | 1 |
| Hubbard, JW | 1 |
| Cox, RH | 1 |
| Sanders, BJ | 1 |
| Lawler, JE | 1 |
| Dellborg, M | 1 |
| Carlsson, M | 1 |
| Nilsson, C | 1 |
| Metz, S | 2 |
| Klein, C | 2 |
| Morton, N | 2 |
| Vizi, ES | 1 |
| Mastrianni, JA | 3 |
| Ingenito, AJ | 3 |
| Nilsson-Ehle, P | 1 |
| Ekberg, M | 1 |
| Fridström, P | 1 |
| Ursing, D | 1 |
| Lins, LE | 2 |
| Zuccalà, A | 1 |
| Santoro, A | 1 |
| Ferrari, G | 1 |
| Zucchelli, P | 1 |
| Lee, DD | 1 |
| DeQuattro, V | 1 |
| Davison, GC | 1 |
| Kimura, S | 1 |
| Barndt, R | 1 |
| Sullivan, P | 1 |
| Mikunis, RI | 1 |
| Monastyrskiĭ, IuI | 1 |
| Pshelutskiĭ, FF | 1 |
| Serkova, VK | 1 |
| Demidiuk, VT | 1 |
| Nakada, T | 1 |
| Kimura, M | 1 |
| Watanabe, H | 1 |
| Yamori, Y | 1 |
| Lovenberg, W | 1 |
| Hajós, M | 1 |
| Spencer, DG | 1 |
| Yaden, S | 2 |
| Lal, H | 2 |
| Lee, SS | 1 |
| Kim, H | 1 |
| Park, YC | 1 |
| Song, JH | 1 |
| Lee, MH | 1 |
| Chung, ES | 1 |
| Lee, SJ | 1 |
| Imm, CW | 1 |
| Gaida, W | 1 |
| Lang, RE | 1 |
| Ganten, D | 1 |
| Greminger, P | 1 |
| Fernandez-Roman, M | 1 |
| Urdin, MC | 1 |
| Kono, Y | 1 |
| Amatsu, K | 1 |
| Armah, BI | 1 |
| Hofferber, E | 1 |
| Stenzel, W | 1 |
| Mallet, L | 1 |
| Cooper, JW | 1 |
| Batra, YK | 1 |
| Indu, B | 1 |
| Puri, GD | 1 |
| Zhao, GS | 1 |
| Guo, JZ | 1 |
| Kraft, KS | 1 |
| Behrendt, M | 1 |
| Lambás-Señas, L | 1 |
| Fluckiger, JP | 1 |
| Sonnay, M | 1 |
| Chamba, G | 1 |
| Renaud, B | 1 |
| Bhadoria, DP | 1 |
| Srivastava, AK | 1 |
| Sharma, M | 1 |
| Deswal, A | 1 |
| Bhadoria, P | 1 |
| Malhotra, KK | 1 |
| Horning, JR | 1 |
| Simmons, JL | 1 |
| McNulty, R | 1 |
| Fried, M | 1 |
| Schwander, J | 1 |
| Hwang, IS | 1 |
| Ho, H | 1 |
| Reaven, GM | 1 |
| Lewis, GR | 1 |
| Frishman, WH | 1 |
| Sherman, D | 1 |
| Feinfeld, DA | 1 |
| Román, O | 1 |
| Gac, JC | 1 |
| Sudy, E | 1 |
| Valenzuela, MA | 1 |
| Michael, M | 1 |
| Brammer, S | 1 |
| Stimpel, M | 1 |
| Schürmeyer, T | 1 |
| Ivens, K | 1 |
| Wambach, G | 1 |
| Volkmann, HP | 1 |
| von zur Mühlen, A | 1 |
| Byrd, BF | 1 |
| Collins, HW | 1 |
| Wasserberger, J | 1 |
| Ordog, GJ | 1 |
| Akhmedkhanov, SSh | 1 |
| Björkqvist, SE | 1 |
| Hauger-Klevene, JH | 1 |
| Wilson, MF | 1 |
| Haring, O | 1 |
| Lewin, A | 1 |
| Bedsole, G | 1 |
| Stepansky, W | 1 |
| Fillingim, J | 1 |
| Hall, D | 1 |
| Roginsky, M | 1 |
| Jagger, P | 1 |
| Hui, TP | 1 |
| Krakoff, LR | 1 |
| Felton, K | 1 |
| Yeager, K | 1 |
| Balldin, J | 1 |
| Bokström, K | 1 |
| Saris, S | 1 |
| Paran, E | 1 |
| Cristal, N | 1 |
| Bies, C | 1 |
| Fagan, T | 1 |
| Valvo, EV | 1 |
| Nazzari, M | 1 |
| Neubauer, JA | 1 |
| Hockenberry, B | 1 |
| Borík, O | 1 |
| Rumlová, L | 1 |
| Okada, S | 1 |
| Miyai, Y | 1 |
| Masaki, Y | 1 |
| Higuchi, T | 1 |
| Ogino, Y | 1 |
| Ota, Z | 1 |
| Catapano, MS | 1 |
| Marx, JA | 1 |
| Magagna, A | 1 |
| McChesney, JA | 1 |
| Shaw, RE | 1 |
| Fishman-Rosen, J | 1 |
| Murphy, MC | 1 |
| Gilkeson, GS | 1 |
| Delaney, RL | 1 |
| Kobaleva, ZhD | 1 |
| Turkkan, JS | 1 |
| Prokocimer, PG | 1 |
| Maze, M | 1 |
| Longnecker, DE | 1 |
| Calvillo, O | 1 |
| Bernard, WD | 1 |
| Lander, RD | 1 |
| Covinsky, JO | 1 |
| Lin, SK | 1 |
| Ribeiro, LG | 1 |
| Feldstein, JS | 1 |
| de Roquefeuil, F | 1 |
| Goupil, C | 1 |
| Pina, IL | 1 |
| Smith, EV | 1 |
| Kessler, KM | 1 |
| Myerburg, RJ | 1 |
| Muñiz Grijalvo, O | 1 |
| Lapetra Peralta, J | 1 |
| Villar Ortiz, J | 1 |
| González de la Puente, MA | 1 |
| Marks, AD | 1 |
| Adlin, EV | 1 |
| Channick, BJ | 1 |
| Zimlichman, R | 2 |
| Stull, R | 2 |
| Folio, CJ | 1 |
| Marmo, E | 1 |
| Filippelli, W | 1 |
| Marrazzo, R | 1 |
| Russo, S | 1 |
| Cazzola, M | 1 |
| Vacca, C | 1 |
| Achimastos, A | 1 |
| Girerd, X | 1 |
| Simon, AC | 1 |
| Pithois-Merli, I | 1 |
| Levenson, J | 1 |
| Datar, S | 1 |
| Laverty, WH | 1 |
| McNeill, JR | 1 |
| Maiorano, G | 1 |
| Contursi, V | 1 |
| Petrelli, G | 1 |
| Loiacono, N | 1 |
| Bovenzi, F | 1 |
| Ricapito, M | 1 |
| Nolan, PL | 1 |
| Johnston, CI | 2 |
| Magioncalda, A | 1 |
| Setti, S | 1 |
| Cecchi, A | 1 |
| Tampoia, V | 1 |
| Bennio, M | 1 |
| Visani, L | 1 |
| Sullivan, PA | 1 |
| De Quattro, V | 1 |
| Foti, A | 1 |
| Curzon, G | 1 |
| Stroev, IuI | 1 |
| Leviashvili, BI | 1 |
| Huisjes, HJ | 1 |
| Hadders-Algra, M | 1 |
| Touwen, BC | 1 |
| Wright, KC | 1 |
| Agre, JC | 1 |
| Wilson, BC | 1 |
| Theologides, A | 1 |
| Harris, TM | 1 |
| White, TM | 1 |
| Guidry, JR | 1 |
| Niemann, JT | 1 |
| Getzug, T | 1 |
| Murphy, W | 1 |
| Bela, M | 1 |
| Kiejna, A | 1 |
| Krakiewicz, A | 1 |
| Leszek, J | 1 |
| Renard, M | 1 |
| Liebens, I | 1 |
| Waterschoot, P | 1 |
| Bernard, R | 1 |
| Ng-Wing Tin, L | 1 |
| Frelon, JH | 1 |
| Beauté, Y | 1 |
| Pellerin, M | 1 |
| Guillaumin, JP | 1 |
| Bazin, C | 1 |
| Karachalios, GN | 1 |
| Maibach, HI | 1 |
| Hartikainen-Sorri, AL | 1 |
| Heikkinen, JE | 1 |
| Koivisto, M | 1 |
| La Vecchia, M | 1 |
| Vergara, G | 1 |
| Iannuzzi, G | 1 |
| Simonetti, A | 1 |
| Cimmino, G | 1 |
| Saulino, C | 1 |
| Novelli Genuino, G | 1 |
| Valerio, V | 1 |
| Kindler, J | 1 |
| Moedder, G | 1 |
| Sieberth, HG | 1 |
| Krane, NK | 1 |
| Bergman, S | 1 |
| Morgan, M | 1 |
| Tuimala, R | 1 |
| Punnonen, R | 1 |
| Kauppila, E | 1 |
| Castellani, S | 1 |
| Passavanti, G | 1 |
| Thanki, B | 1 |
| Gosse, P | 1 |
| Wicker, P | 1 |
| Roudaut, R | 1 |
| Danays, T | 1 |
| Dallocchio, M | 1 |
| Kelley, S | 1 |
| Squadrito, F | 1 |
| Quattrone, G | 1 |
| Buemi, M | 1 |
| Frisina, N | 1 |
| Caputi, AP | 1 |
| Squadrito, G | 1 |
| Hiremath, A | 1 |
| Michael, R | 1 |
| Kanniainen, E | 2 |
| Heikkilä, O | 1 |
| Jääskeläinen, T | 1 |
| Seedat, YK | 2 |
| Ferlito, S | 1 |
| Indelicato, G | 1 |
| Di Vincenzo, S | 1 |
| Del Campo, F | 1 |
| La Vignera, A | 1 |
| Fichera, C | 1 |
| Yajnik, BH | 1 |
| Shah, JS | 1 |
| Castellano, G | 1 |
| Santalla, F | 1 |
| Puras, A | 1 |
| Alvarez Machín, N | 1 |
| Vidal, JV | 1 |
| Morillas, JD | 1 |
| Muñoz, MT | 1 |
| Solís Herruzo, JA | 1 |
| Meese, RB | 1 |
| Guffanti, E | 1 |
| Vaccarella, A | 1 |
| Meregalli, M | 1 |
| Fiorella, G | 1 |
| Chierichetti, SM | 1 |
| Mazzola, C | 1 |
| Phippard, A | 2 |
| Henderson-Smart, DJ | 1 |
| Child, A | 2 |
| Ikäheimo, M | 1 |
| Rössner, S | 1 |
| Wilkinson, AH | 1 |
| Stone, FA | 1 |
| Saad, N | 1 |
| Rybak, MJ | 1 |
| Varshchitskiĭ, MG | 1 |
| Schaller, MD | 1 |
| Porchet, M | 1 |
| Levinson, PD | 1 |
| Pitterman, A | 1 |
| Abbott, FV | 1 |
| Frewin, DB | 1 |
| Struthers, AD | 1 |
| Adams, EF | 1 |
| Smith, LJ | 1 |
| Sussman, AM | 1 |
| Serra, M | 1 |
| Reinhart, S | 1 |
| Barrett, SM | 1 |
| Sved, AF | 1 |
| Mastrangelo, F | 1 |
| Rizzelli, S | 1 |
| Corlianò, C | 1 |
| Alfonso, L | 1 |
| De Blasi, V | 1 |
| Aprile, M | 1 |
| Montinaro, AM | 1 |
| Napoli, M | 1 |
| Hall, BM | 1 |
| Cerasola, G | 1 |
| Marozzi, P | 1 |
| Morici, ML | 1 |
| Cottone, S | 1 |
| D'Ignoto, G | 1 |
| Grasso, L | 1 |
| Bompiani, GD | 1 |
| Scali, G | 1 |
| Bompani, R | 1 |
| Nagahama, S | 1 |
| Dawson, R | 1 |
| Brandstetter, K | 1 |
| Krause, U | 1 |
| Beyer, J | 1 |
| Campbell, BC | 1 |
| Gilbert, JC | 1 |
| Sau, F | 1 |
| Seguro, C | 1 |
| Bonomo, P | 1 |
| Cherchi, A | 1 |
| Hong, E | 1 |
| Moreno, JA | 1 |
| Nava-Félix, P | 1 |
| Hardman, SL | 1 |
| Shirachi, DY | 1 |
| Kastrup, J | 1 |
| Smidt, UM | 1 |
| Gorchien, A | 1 |
| Webster, J | 1 |
| Jeffers, A | 1 |
| Galloway, DB | 1 |
| Petrie, JC | 1 |
| Vorburger, C | 2 |
| Tuckman, J | 1 |
| Schneider, KW | 1 |
| Fritel, D | 1 |
| Baglin, A | 2 |
| Lagrue, G | 3 |
| Bloch-Laine, JF | 1 |
| Milliez, P | 4 |
| Trocme, C | 1 |
| Hansson, L | 3 |
| Nast, HP | 1 |
| Weil, B | 1 |
| Buisson, C | 1 |
| Bauer, GE | 2 |
| McNay, JL | 1 |
| Salt, PJ | 1 |
| Iversen, LL | 1 |
| Laverty, R | 1 |
| Alexandre, JM | 1 |
| Page, LB | 1 |
| Sidd, JJ | 1 |
| Negoiţă, CI | 1 |
| Lambelin, G | 1 |
| De Schaepdryver, AF | 1 |
| Romagnoli, GF | 1 |
| Onstad, A | 1 |
| Lopatkin, NA | 1 |
| Mazo, EB | 1 |
| Goriunov, VG | 1 |
| Maĭdanov, ZhT | 1 |
| Poyser, RH | 1 |
| Shorter, JH | 1 |
| Whiting, RL | 1 |
| Leighton, PW | 1 |
| Tighe, H | 1 |
| Dufey, K | 1 |
| Krönig, B | 1 |
| Costa, V | 1 |
| Pirrelli, A | 2 |
| Pieri, R | 2 |
| Arzilli, F | 2 |
| Zucchelli, GC | 1 |
| Leibel, BA | 1 |
| Amery, AK | 1 |
| Bossaert, H | 1 |
| Fagard, RH | 1 |
| Verstraete, M | 1 |
| Dorscheid, HO | 1 |
| Ehinger, U | 1 |
| Hempel, J | 1 |
| Kondziella, W | 1 |
| Schulz, G | 1 |
| Schulz, J | 1 |
| Sziegoleit, W | 1 |
| Wolf, R | 1 |
| Brod, J | 3 |
| Horbach, L | 2 |
| Just, H | 2 |
| Nicolescu, R | 1 |
| Briant, RH | 1 |
| Schwarz, D | 1 |
| Strian, F | 1 |
| Lung-Johansen, P | 1 |
| De Conca, V | 1 |
| Michetti, P | 1 |
| Warembourg, H | 1 |
| Dewailly, P | 1 |
| Lekieffre, J | 1 |
| Ketelers, JY | 1 |
| Anlauf, M | 1 |
| Hoersen, H | 1 |
| Hampel, R | 1 |
| Merguet, P | 1 |
| Quarta-Colosso, M | 1 |
| D'Amelio, G | 1 |
| Dalla Volta, S | 1 |
| De Longhi, B | 1 |
| Razzolini, R | 1 |
| Perrotta, P | 1 |
| Abernethy, JD | 1 |
| Picchione, N | 1 |
| Lageder, H | 1 |
| Hartl, O | 2 |
| Irsigler, K | 1 |
| Barjon, P | 1 |
| Fourcade, J | 1 |
| Dejaco, RM | 1 |
| Reubi, F | 1 |
| Sobel, A | 2 |
| Merceron, R | 1 |
| Heilmann, K | 1 |
| Dymling, JF | 1 |
| Lewis, PJ | 2 |
| Harrison, TS | 1 |
| Lewis, RG | 1 |
| Mitchell, AS | 1 |
| Young, AA | 1 |
| Maclachlan, I | 1 |
| Reyes, AJ | 1 |
| Acosta Barrios, T | 1 |
| Linquette, M | 1 |
| Fossati, P | 1 |
| Fourlinnie, JC | 1 |
| Voimant, YM | 1 |
| Froment, A | 1 |
| Milon, H | 1 |
| Matts, SG | 1 |
| Hashida, J | 1 |
| Amery, A | 1 |
| Vandenbroucke, J | 1 |
| Desbuquoit, JL | 1 |
| De Groote, J | 1 |
| Sayegh, F | 1 |
| Hartmann, J | 1 |
| Weigelin, E | 1 |
| Wichmann, J | 1 |
| Polak, HJ | 1 |
| Koall, W | 1 |
| Teodoresco, P | 1 |
| Câmpeanu, A | 1 |
| Novelli, E | 1 |
| Grillo, A | 1 |
| Kiseleva, ZM | 1 |
| Labeeva, TN | 1 |
| Baksi, AK | 1 |
| Kiriakov, A | 1 |
| Khlebarova, M | 1 |
| Staneva-Stoicheva, D | 1 |
| Panova, I | 1 |
| Weiss, Y | 1 |
| Folliot, A | 1 |
| Turacli, ME | 1 |
| Hutchison, JC | 1 |
| Wilkinson, WH | 1 |
| Lintgen, AB | 1 |
| Vettore, L | 1 |
| Putzeys, MR | 1 |
| Davidov, M | 1 |
| Vidrio, H | 1 |
| Marinova, V | 1 |
| Gelinov, Kh | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multicenter Study of Patients With Hypertension Resistant to Patient Identification and Standardization of Therapeutic[NCT01643434] | Phase 4 | 2,000 participants (Anticipated) | Interventional | 2012-08-31 | Recruiting | ||
| Randomized Clinical Trial for Effectiveness of Clonidine Versus Captopril for Treatment of Postpartum Very High Blood Pressure[NCT01761916] | Phase 4 | 90 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Effect of Clonidine vs. Dexmedetomidine in Addition to Standard Treatment in Agitated Delirium in Intensive Care Patients: Pilot Study.[NCT04758936] | Phase 4 | 50 participants (Anticipated) | Interventional | 2021-02-01 | Recruiting | ||
| Impact of Renal SympAthetic DenerVation on Chronic HypErtension[NCT01628198] | 38 participants (Actual) | Interventional | 2011-10-31 | Terminated (stopped due to recommendation by the study's DSMB due to insufficient data to determine efficacy.) | |||
| Renal Sympathetic Denervation for the Management of Chronic Hypertension[NCT01628172] | 96 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
| Transversus Abdominis Plane (TAP) Block for Cesarean Section[NCT01015807] | 90 participants (Actual) | Interventional | 2009-11-30 | Completed | |||
| Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol[NCT02403349] | Phase 4 | 105 participants (Actual) | Interventional | 2012-05-31 | Active, not recruiting | ||
| The Pathophysiology and Treatment of Supine Hypertension in Patients With Autonomic Failure[NCT00223717] | Phase 1 | 152 participants (Actual) | Interventional | 2001-01-31 | Completed | ||
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| Hemodynamic Effect of Intrathecal Clonidine in Hypertensive Subjects: A Pilot Study to Assess Its Effectiveness in Hypertensive Subjects With Poor Blood Pressure Control (Phase II)[NCT01297335] | Phase 2 | 10 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| A Multicenter Randomized Controlled Trial of Exercise in Aortic Dissection Survivors[NCT05610462] | 126 participants (Anticipated) | Interventional | 2023-01-01 | Active, not recruiting | |||
| Emergency Department Interventions to Improve Blood Pressure Follow-up[NCT00798551] | 10 participants (Actual) | Interventional | 2008-04-16 | Completed | |||
| The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects[NCT01600885] | 16 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma[NCT01967576] | Phase 2 | 14 participants (Actual) | Interventional | 2013-10-19 | Completed | ||
| Diagnosis and Treatment of Pheochromocytoma[NCT00001229] | 240 participants | Observational | 1988-10-31 | Completed | |||
| A Safe Ketamine-Based Therapy for Treatment Resistant Depression[NCT01179009] | 20 participants (Actual) | Interventional | 2012-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The change in diastolic blood pressure as measured by 24 hour ambulatory monitoring at 6 months as compared to from baseline. (NCT01628198)
Timeframe: baseline and 6 months
| Intervention | mmHg mean change (Mean) |
|---|---|
| Renal Denervation Group | -5.5 |
The change in systolic blood pressure as measured by 24 hour ambulatory monitoring at 6 months as compared to from baseline. (NCT01628198)
Timeframe: baseline and 6 months
| Intervention | mmHg (Mean) |
|---|---|
| Renal Denervation Group | -10.2 |
The total number of anti-hypertensive medications at baseline, 6 months, and 12 months (NCT01628198)
Timeframe: Baseline, 6 months, 12 months
| Intervention | medications (Mean) | ||
|---|---|---|---|
| Baseline | 6 months | 12 months | |
| Renal Denervation Group | 5.37 | 4.79 | 4.64 |
A blood urea nitrogen (BUN) test measures the amount of nitrogen in blood that comes from the waste product urea. Urea is made when protein is broken down in the body. Urea is made in the liver and passed out in the urine. (NCT01628198)
Timeframe: baseline, 6 months, 12 months
| Intervention | mg/dL (Mean) | ||
|---|---|---|---|
| Baseline | 6 months | 12 months | |
| Renal Denervation Group | 20.82 | 22.15 | 23.11 |
Creatinine measures the level of the waste product in the body. The amount of creatinine in the blood depends partly on the amount of muscle tissue you have. Men generally have higher creatinine levels than women.Normal levels of creatinine in the blood are approximately 0.6 to 1.2 milligrams (mg) per deciliter (dL) in adult males and 0.5 to 1.1 milligrams per deciliter in adult females. High levels of creatinine indicates kidney impairment. (NCT01628198)
Timeframe: baseline, 6 months, 12 months
| Intervention | mg/dl (Mean) | ||
|---|---|---|---|
| Baseline | 6 months | 12 months | |
| Renal Denervation Group | 1.6 | 1.68 | 2.03 |
Different time points office diastolic blood pressure measurements (NCT01628198)
Timeframe: baseline, 6 month, 12 months
| Intervention | mm Hg (Mean) | ||
|---|---|---|---|
| Baseline | 6 months | 12 months | |
| Renal Denervation Group | 87.06 | 86.93 | 87.75 |
Different time points office systolic blood pressure measurements (NCT01628198)
Timeframe: baseline, 6 month, 12 months
| Intervention | mm Hg (Mean) | ||
|---|---|---|---|
| Baseline | 6 months | 12 months | |
| Renal Denervation Group | 156.86 | 151.19 | 158.45 |
Renal artery blood flow as measured by Renal Aortic Ratio (RAR) = Peak systolic Velocity renal artery / Peak Systolic Velocity Aorta. A >60% stenosis is reported when there is a >3.5:1 Renal to Aortic Ratio. (NCT01628198)
Timeframe: Baseline and 12 months
| Intervention | ratio (Mean) | |||
|---|---|---|---|---|
| Baseline Right RAR | Baseline Left RAR | 12 months Right RAR | 12 months Left RAR | |
| Renal Denervation Group | 1.38 | 1.52 | 1.41 | 1.52 |
Dimensions of renal artery, right and left (NCT01628198)
Timeframe: baseline and 12 months
| Intervention | mm (Mean) | |||
|---|---|---|---|---|
| Baseline R Kidney | Baseline L Kidney | 12 months R Kidney | 12 months L Kidney | |
| Renal Denervation Group | 11.43 | 11.68 | 11.26 | 11.39 |
Renal artery blood flow as measured by Resistive Index. RI = (peak systolic velocity - end diastolic velocity ) / peak systolic velocity. the normal value is ~ 0.60, with 0.70 being around the upper limits of normal (NCT01628198)
Timeframe: Baseline and 12 months
| Intervention | index (Mean) | |||
|---|---|---|---|---|
| Baseline Right RI | Baseline Left RI | 12 months Right RI | 12 months Left RI | |
| Renal Denervation Group | 0.67 | 0.72 | 0.72 | 0.72 |
Determine which of three different TAP formulations (Placebo, TAP, Clo-TAP) has the most beneficial effect on the postoperative area of hyperalgesia 48hrs after the start of the cesarean section. The smaller the area of WHA, assessed in cm2, the better the outcome. Area sizes may range from 0 to any size. (NCT01015807)
Timeframe: 48hrs after CS
| Intervention | cm^2 (Mean) |
|---|---|
| Placebo | 1.07 |
| TAP (Bupi) | 1.27 |
| Clo-TAP (Bupi + Clon) | 0.74 |
"Subjects baseline blood pressure (systolic blood pressure (SBP), and diastolic blood pressure (DBP)), and blood pressures after clonidine injection was compared against baseline to assess efficacy of clonidine in refractory hypertensive subjects. Subject's blood pressure was monitored continuously after intrathecal injection of clonidine until subjects blood pressure nadir and return to pre clonidine injection level. The mean value reported below are the average changes in blood pressure from baseline (pre clonidine injection) in both SBP and DBP during post clonidine injection blood pressure monitoring for 4 hours.~Blood pressure measurements were collected every 10 minutes for first hour after injection, and every 15 minutes after the first hour, up to 4 hours were averaged to report the change from baseline." (NCT01297335)
Timeframe: Baseline, Every 10 Minutes for first hour after clonidine injection, and every 15 minutes after first hour, until 4 hours after clonidine injection
| Intervention | mm Hg (Mean) | |
|---|---|---|
| Change in mean SBP after clonidine injection | Change in DBP after clonidine injection | |
| Intrathecal Clonidine | 79 | 37 |
Subjects were asked to rate severity of two of the most common side effects of clonidine, sedation and sensation of dry mouth, at pre and post (1 hour after) intrathecal administration of clonidine. The mean changes between pre and post injection VAS ratings of sedation and sensation of dry mouth are reported below. The VAS scale ranges from 1 to 10 cm, with higher values indicating higher level of sedation and higher level of dry mouth. (NCT01297335)
Timeframe: Before clonidine injection (Baseline), and at 1 hour after clonidine injection.
| Intervention | cm (Mean) | |
|---|---|---|
| Change in level of sedation | Change in sensation of dry mouth | |
| Intrathecal Clonidine | 3.36 | 3.47 |
Likert scale is 11 point digital pain rating system that asks subjects to rate their pain from 0 to 10. Rating of 0 means no pain at all, and in increasing order, 10 would mean worst pain imaginable/ unbearable pain. (NCT01297335)
Timeframe: Pre-dose and 1 hour post injection.
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pre-injection average Likert score | Post-injection average Likert score | |
| Intrathecal Clonidine | 6.5 | 3.6 |
"Scans will be analyzed for task-related prefrontal activation~Difference Score: Percent Signal Change in Regions of Interest (ketamine - saline)" (NCT01600885)
Timeframe: Within 4 hours of dose administration, after up to 1.25 hours of ketamine infusion
| Intervention | percent change in saline signal (Mean) |
|---|---|
| Guanfacine | -0.17 |
| Placebo | -0.094 |
Difference Score: Percent Signal Change in Regions of Interest (ketamine - saline) (NCT01600885)
Timeframe: Within 4 hours of dose administration, after up to 1.25 hours of ketamine infusion
| Intervention | percent change in saline signal (Mean) |
|---|---|
| Guanfacine | -0.1 |
| Placebo | 0.052 |
Difference Score: Percent Signal Change in Regions of Interest (ketamine - saline) (NCT01600885)
Timeframe: Within 4 hours of dose administration, after up to 1.25 hours of ketamine infusion
| Intervention | percent change in saline signal (Mean) |
|---|---|
| Guanfacine | -0.134 |
| Placebo | -0.086 |
Here is the count of participants with serious and non-serious adverse events assessed by the Common Terminology Criteria in Adverse Events (CTCAE v4.0). A non-serious adverse event is any untoward medical occurrence. A serious adverse event is an adverse event or suspected adverse reaction that results in death, a life threatening adverse drug experience, hospitalization, disruption of the ability to conduct normal life functions, congenital anomaly/birth defect or important medical events that jeopardize the patient or subject and may require medical or surgical intervention to prevent one of the previous outcomes mentioned. (NCT01967576)
Timeframe: Date treatment consent signed to date off study, approximately 54 months and 29 days.
| Intervention | Participants (Count of Participants) |
|---|---|
| 1/Arm 1-Axitinib | 14 |
PFS is defined as the duration of time from start of treatment to time of progression or death, whichever comes first. Disease progression was assessed by the Response Evaluation Criteria in Solid Tumors (RECIST) and is defined as at least a 20% increase in the sum of the diameters of target lesions, taking as reference the smallest sum on study (this includes the baseline sum if that is the smallest on study). In addition to the relative increase of 20%, the sum must also demonstrate an absolute increase of at least 5 mm. (Note: the appearance of one or more new lesions is also considered progressions). (NCT01967576)
Timeframe: time from start of treatment to time of progression or death, up to 5 years and 9 months
| Intervention | months (Median) |
|---|---|
| 1/Arm 1-Axitinib | 7.7 |
Response was assessed by the Response Evaluation Criteria in Solid Tumors (RECIST). Partial Response (PR) is at least a 30% decrease in the sum of the diameters of target lesions, taking as reference the baseline sum diameters. Complete Response (CR) is disappearance of all target lesions. Any pathological lymph nodes (whether target or no-target) must have reduction in short axis to <10 mm. Stable Disease (SD) is neither sufficient shrinkage to qualify for PR nor sufficient increase to qualify for PD, taking as reference the smallest sum diameters while on study. Progressive Disease (PD) is at least a 20% increase in the sum of the diameters of target lesions, taking as reference the smallest sum on study (this includes the baseline sum if that is the smallest on study). (NCT01967576)
Timeframe: Patients were assessed every 12 weeks (+/- week) up to 40.6 months
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Confirmed Partial Response | Complete Response | Stable Disease | Progressive Disease | |
| 1/Arm 1-Axitinib | 5 | 0 | 5 | 2 |
The Montgomery-Asberg Depression Rating Scale (MADRS) is a 10-item scale that measures the severity of depression, with a higher score indicating a higher level of depression. The range of scores is 0 to 60. (NCT01179009)
Timeframe: 8 weeks
| Intervention | Scores on a scale (Mean) |
|---|---|
| Ketamine 100-hour Infusion | -9.0 |
| Ketamine 40-minute Infusion | -6.4 |
127 reviews available for clonidine and Hypertension
| Article | Year |
|---|---|
Excessive Blood Pressure Response to Clonidine in Hospitalized Patients With Asymptomatic Severe Hypertension.
Topics: Blood Pressure; Clonidine; Female; Humans; Hypertension; Incidence; Male; Middle Aged | 2022 |
[HTA and non-hormonal menopause treatment].
Topics: Acupuncture Therapy; Clonidine; Complementary Therapies; Female; Gabapentin; Hot Flashes; Humans; Hy | 2019 |
Recent advances in understanding and managing resistant/refractory hypertension.
Topics: Antihypertensive Agents; Bisoprolol; Catheters; Clinical Trials as Topic; Clonidine; Denervation; Do | 2020 |
Treatment and Prevention of Hypertensive Disorders During Pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Chronic Dis | 2019 |
Catecholamine excess: pseudopheochromocytoma and beyond.
Topics: Adrenal Gland Neoplasms; Adrenergic Agents; Antihypertensive Agents; Autonomic Nervous System Diseas | 2015 |
Orthostatic hypotension: pathophysiology, assessment, treatment and the paradox of supine hypertension.
Topics: Antihypertensive Agents; Antiparkinson Agents; Clonidine; Disease Management; Domperidone; Dopamine | 2017 |
Sympathetic activation in chronic renal failure.
Topics: Animals; Cardiovascular Diseases; Catecholamines; Clonidine; Debrisoquin; Disease Models, Animal; Ef | 2009 |
Sympathetic activation in chronic renal failure.
Topics: Animals; Cardiovascular Diseases; Catecholamines; Clonidine; Debrisoquin; Disease Models, Animal; Ef | 2009 |
Sympathetic activation in chronic renal failure.
Topics: Animals; Cardiovascular Diseases; Catecholamines; Clonidine; Debrisoquin; Disease Models, Animal; Ef | 2009 |
Sympathetic activation in chronic renal failure.
Topics: Animals; Cardiovascular Diseases; Catecholamines; Clonidine; Debrisoquin; Disease Models, Animal; Ef | 2009 |
Older blood pressure medications-do they still have a place?
Topics: Antihypertensive Agents; Chlorthalidone; Clonidine; Diuretics; Ethacrynic Acid; Guanethidine; Humans | 2011 |
Clonidine toxicity revisited.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Clonidine; Drug Overdose; Female; Humans; Hypertension | 2002 |
Pheochromocytoma: an approach to antihypertensive management.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive | 2002 |
Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension.
Topics: Antihypertensive Agents; Circadian Rhythm; Clonidine; Guanabenz; Humans; Hypertension | 2003 |
[Centrally-acting antihypertensive drugs].
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Guanabenz; Guanfacine; Humans; Hypertension; Imi | 2004 |
Centrally acting antihypertensive agents: an update.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Blood Pressure; Clonidine; Contraindications; Gu | 2007 |
Centrally acting antihypertensive agents: a brief overview.
Topics: Animals; Antihypertensive Agents; Central Nervous System; Clonidine; Guanabenz; Humans; Hypertension | 1984 |
Drugs five years later: clonidine.
Topics: Animals; Blood Pressure; Brain; Clonidine; Evaluation Studies as Topic; Humans; Hypertension; Neurot | 1980 |
The management of hypertension in pregnancy: A review.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticoagu | 1980 |
[Current treatment of hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Guanethidine; Human | 1980 |
[Therapy of essential arterial hypertension. V].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Drug Evaluation; Drug Therapy, Comb | 1980 |
[Bases of pharmacological therapy of essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Antihypertensive Agents; Captopril; Clonidine | 1980 |
Withdrawal syndromes and the cessation of antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Humans; Hypertension; Propranolol; | 1981 |
Abrupt cessation of treatment in hypertension: consideration of clinical features, mechanisms, prevention and management of the discontinuation syndrome.
Topics: Acute Disease; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Bethanidine; Blood Pressure; Cloni | 1981 |
[Clinical aspects of antihypertensive drug therapy].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; C | 1982 |
Review of therapeutic modalities acting directly via central pathways.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Brain; Catecholamines | 1982 |
[Side effects of hypotensive agents].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Bradycardia; Clonidine; Deh | 1982 |
The hypertensive surgical patient. Controversies in management.
Topics: Adrenal Gland Neoplasms; Adrenergic beta-Antagonists; Adult; Anesthesia; Animals; Antihypertensive A | 1983 |
Clinical considerations for the hypertensive patient in podiatric practice.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Human | 1983 |
[Adrenergic receptors. Their clinical significance in hypertension].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Clonidine; Humans; Hypert | 1983 |
Biochemical characteristics and regulation of brain alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain; Clonidine; Epinephrine; Hum | 1984 |
Hypertension in pregnancy. Pathophysiology and management.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Clon | 1984 |
Central and peripheral blockade of the sympathetic nervous system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; | 1984 |
Role of alpha adrenoceptors in hypertension and in antihypertensive drug treatment.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Azepines; | 1984 |
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihyp | 1984 |
Profiling the hypertensive patient in sports.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Diuretic | 1984 |
Clonidine and the kidney.
Topics: Adrenal Gland Neoplasms; Aldosterone; Antihypertensive Agents; Catecholamines; Clonidine; Humans; Hy | 1980 |
Clonidine in the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clonidine; Diuretics; Drug Therapy, Combination; | 1980 |
Labetalol and the management of hypertension.
Topics: Adrenal Gland Neoplasms; Clonidine; Ethanolamines; Humans; Hypertension; Labetalol; Pheochromocytoma | 1981 |
Alpha-adrenergic receptor subtypes.
Topics: Animals; Binding, Competitive; Clonidine; Dihydroergotoxine; Epinephrine; Heart Rate; Humans; Hypert | 1980 |
Drug systems approach to hypertension.
Topics: Captopril; Clonidine; Drug Combinations; Drug Therapy, Combination; Guanethidine; Humans; Hydralazin | 1984 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
Peripheral dopamine receptors, potential targets for a new class of antihypertensive agents. Part II: Sites and mechanisms of action of dopamine receptor agonists.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Ergolines; Heart Rate; Hypertension; Mo | 1982 |
[Hemodynamic effects of intravenous clonidine in patients with acute myocardial infarction].
Topics: Adult; Clonidine; Female; Hemodynamics; Humans; Hypertension; Injections, Intravenous; Male; Middle | 1982 |
Anti-hypertensive drugs in the pregnant patient.
Topics: Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Diuretics; Female; Fetus; Furosemide | 1980 |
Antihypertensive pharmacology.
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; H | 1980 |
Hypertensive emergencies: practical approach to treatment.
Topics: Administration, Oral; Antihypertensive Agents; Child; Clonidine; Diazoxide; Emergencies; Female; Hum | 1980 |
[Therapy of hypertensive crisis].
Topics: Acute Disease; Bed Rest; Cardiac Glycosides; Clonidine; Diazoxide; Dihydralazine; Diuretics; Heart F | 1980 |
[Acute clinidine intoxication. Critical review].
Topics: Adult; Arrhythmias, Cardiac; Clonidine; Female; Heroin Dependence; Humans; Hypertension; Male; Self | 1981 |
Management of systemic hypertension in children.
Topics: Adolescent; Antihypertensive Agents; Child; Clonidine; Diazoxide; Diet, Sodium-Restricted; Diuretics | 1982 |
Clinical pharmacology of drugs acting on imidazoline and adrenergic receptors. Studies with clonidine, moxonidine, rilmenidine, and atenolol.
Topics: Antihypertensive Agents; Atenolol; Clinical Trials as Topic; Clonidine; Humans; Hypertension; Imidaz | 1995 |
[Imidazole receptors and blood pressure regulation. High receptor selectivity of moxonidine].
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Humans | 1993 |
Oral antihypertensives for hypertensive urgencies.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Female; Humans; | 1994 |
The USA experience with the clonidine transdermal therapeutic system.
Topics: Administration, Cutaneous; Clonidine; Humans; Hypertension; Patient Compliance; Treatment Outcome; U | 1993 |
[The imidazoline receptor and the central regulation of arterial pressure].
Topics: Blood Pressure; Catecholamines; Central Nervous System; Clonidine; Humans; Hypertension; Imidazoline | 1993 |
The I1-imidazoline receptor: from binding site to therapeutic target in cardiovascular disease.
Topics: Animals; Antihypertensive Agents; Binding Sites; Clonidine; Humans; Hypertension; Imidazoles; Imidaz | 1997 |
[Centrally acting sympathetic inhibitors for therapy of patients with hypertension].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic Fibers; Antihypertensive Agents; Clonidine; Guanfac | 1997 |
Is the hypotensive effect of clonidine and related drugs due to imidazoline binding sites?
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Binding Sites; Blood Pressure; Clonidin | 1997 |
Clonidine suppression test revisited.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Clonidine; Creatinine; Epinephrine; Female; Hemodynamics; Huma | 1998 |
Alpha 2-agonist agents: a review for CRNAs.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Clonidine; Humans; Hypertension; Nurse Anesthetist | 1998 |
Intravenous clonidine for hypertensive emergencies.
Topics: Antihypertensive Agents; Clonidine; Drug Administration Schedule; Emergency Treatment; Humans; Hyper | 1999 |
Thalamic hemorrhage following carotid endarterectomy-induced labile blood pressure: controlling the liability with clonidine--a case report.
Topics: Aged; Antihypertensive Agents; Baroreflex; Blood Pressure Monitoring, Ambulatory; Cerebral Hemorrhag | 1999 |
[Clinical pharmacology of hypotensive drugs acting on central imidazoline receptors].
Topics: Antihypertensive Agents; Clonidine; Drug Interactions; Humans; Hypertension; Imidazoles; Imidazoline | 1998 |
Central I1-imidazoline receptors as targets of centrally acting antihypertensive drugs. Clinical pharmacology of moxonidine and rilmenidine.
Topics: Animals; Antihypertensive Agents; Brain; Clinical Trials as Topic; Clonidine; Hemodynamics; Humans; | 1999 |
Diagnosis and management of hypertensive emergencies.
Topics: Adrenergic alpha-Agonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aortic | 1999 |
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Fema | 2000 |
Diagnosis and management of baroreflex failure.
Topics: Antihypertensive Agents; Autonomic Nervous System Diseases; Baroreflex; Bradycardia; Carotid Sinus; | 1995 |
I1 receptors, cardiovascular function, and metabolism.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Cardiovascular System; Clonidine; Humans; Hypert | 2001 |
Imidazoline antihypertensive drugs: a critical review on their mechanism of action.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hypertension; Imidazoles; Medul | 2002 |
[Management of high blood pressure using beta-sympatholytics. Review].
Topics: Adrenergic beta-Antagonists; Clonidine; Furosemide; Guanethidine; Humans; Hydralazine; Hypertension; | 1976 |
Hypertension: which beta-blocker?
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Biological Availability; Brain; Cloni | 1976 |
Clinical pharmacology of antihypertensive drugs.
Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blo | 1977 |
Recent advances in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Chronic Disease; Clonidine; Diazoxide; Drug Th | 1977 |
[Current treatment of arterial hypertension].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Clonidine; Dihydralazine; F | 1977 |
The use of antihypertensive drugs in hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretic | 1977 |
Antihypertensive drugs: clinical pharmacology and therapeutic use.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertens | 1977 |
[Etiology, pathogenesis and epidemiology of hypertension].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Animals; Benzothiadiazines; Cardiac Output; Cl | 1978 |
Correlation of pharmacological effects with plasma levels of antihypertensive drugs in man.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Guanethidine; Humans; | 1979 |
[Epidemiological, diagnostic and therapeutic aspects of hypertension in adolescence].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Age Factors; Clonidine; Diazoxide; Diuretics; Female | 1979 |
[Cardiac therapy in the old patient].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycos | 1979 |
Drug treatment of hypertension.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agent | 1975 |
Drug-induced hypertension: pathogenesis and management.
Topics: Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Antidepressive Agents, Tricyclic; Carbenox | 1976 |
[Antihypertensive drugs acting through neurogenic mechanisms].
Topics: Animals; Antihypertensive Agents; Brain; Clonidine; Hypertension; Methyldopa; Rabbits; Receptors, Ad | 1977 |
Preventing, detecting and managing adverse reactions of antihypertensive agents in the ambulant patient with essential hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Ethacrynic Acid | 1977 |
New drugs in hypertension.
Topics: Antihypertensive Agents; Bethanidine; Clonidine; Debrisoquin; Female; Humans; Hypertension; Male; Pr | 1977 |
Recent acquisitions in antihypertensive therapy: clonidine, minoxidil and prazosin.
Topics: Animals; Clonidine; Dogs; Hemodynamics; Humans; Hypertension; Minoxidil; Prazosin; Pyrimidines; Quin | 1978 |
[Clonidine and central sympathetic nervous system blockaders].
Topics: Animals; Clonidine; Dogs; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Renin; Symp | 1978 |
Drug therapy of hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Evaluation; Huma | 1978 |
The therapeutic uses of clonidine.
Topics: Blood Pressure; Climacteric; Clonidine; Female; Glaucoma; Hemodynamics; Humans; Hypertension; Kidney | 1979 |
[The sympathetic nervous system and essential hypertension].
Topics: Atenolol; Catecholamines; Clonidine; Guanethidine; Humans; Hypertension; Methyldopa; Norepinephrine; | 1979 |
Renin and the therapy of hypertension.
Topics: Animals; Antihypertensive Agents; Cardiovascular Diseases; Clonidine; Diazoxide; Diuretics; Dogs; Fe | 1976 |
Central sympathetic transmitters and hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Cardiac Output; Cats; Clonidine; Dihydroxyphenylalanine; Dog | 1975 |
Cardiovascular regulation by central adrenergic mechanisms and its alteration by hypotensive drugs.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain Mapping; Brain Stem; Cardiovascular System; | 1975 |
Drug therapy: clonidine, a new antihypertensive drug.
Topics: Blood Pressure; Brain; Clonidine; Drug Interactions; Drug Therapy, Combination; Hemodynamics; Humans | 1975 |
The clinician's guide to pharmacology of antihypertensive agents.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Hemodynami | 1976 |
Imidazoline receptors. A new concept in central regulation of the arterial blood pressure.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Hypertension; Imidazoline Receptors; | 1992 |
Use of centrally acting sympatholytic agents in the management of hypertension.
Topics: Aged; Clonidine; Guanfacine; Heart; Humans; Hypertension; Kidney; Methyldopa; Sympatholytics | 1991 |
Your patient and angina.
Topics: Angina Pectoris; Clonidine; Drug Interactions; Female; Flurazepam; Furosemide; Humans; Hypertension; | 1991 |
Management of hypertension by reduction in sympathetic activity.
Topics: Behavior Therapy; Blood Pressure; Body Weight; Clonidine; Humans; Hypertension; Methyldopa; Sympathe | 1991 |
[Clonidine: from the treatment of hypertension to its use in anesthesia. I. Main effects and mechanism of action of clonidine].
Topics: Analgesia; Anesthesia; Autonomic Nervous System; Clonidine; Hemodynamics; Humans; Hydrocarbons, Halo | 1990 |
[Clonidine: from the treatment of hypertension to its use in anesthesia. II: Perioperative use].
Topics: Analgesia; Anesthesia; Anesthetics; Animals; Clonidine; Hemodynamics; Humans; Hypertension; Hypotens | 1990 |
Comparison of pharmacokinetics and pharmacodynamics of adrenoceptor agonists and antagonists as antihypertensive agents.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Blood Pressure; Clonidine; Doxazosin; Human | 1987 |
Cerebrospinal fluid norepinephrine levels in essential hypertension: effects of drug treatment and withdrawal.
Topics: Adult; Clonidine; Dopamine; Double-Blind Method; Epinephrine; Humans; Hypertension; Methyldopa; Midd | 1987 |
A review of contact dermatitis associated with transdermal therapeutic systems.
Topics: Administration, Cutaneous; Administration, Oral; Clonidine; Dermatitis, Contact; Estradiol; Humans; | 1989 |
[Primary hyperaldosteronism caused by unilateral macronodular hyperplasia].
Topics: Adrenal Gland Diseases; Adrenal Glands; Adult; Clonidine; Follow-Up Studies; Humans; Hyperaldosteron | 1989 |
Behaviour and hypertension: a pathophysiological puzzle.
Topics: Arousal; Atenolol; Autonomic Nervous System; Blood Pressure; Clonidine; Humans; Hypertension; Muscle | 1989 |
Bronchial effects of alpha 2-adrenoceptor agonists and of other antihypertensive agents in asthma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; An | 1989 |
Clinical pharmacology of centrally acting antihypertensive agents.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Guanfacine; Gu | 1989 |
Fetal effects of maternally administered clonidine and angiotensin-converting enzyme inhibitors.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Clonidine; Female; Fetus; Humans; Hypertension; Mat | 1989 |
Mono-aminergic receptors and blood pressure.
Topics: Adrenergic beta-Agonists; Blood Pressure; Catechol O-Methyltransferase; Cell Membrane; Clonidine; Do | 1985 |
Hypertension in pregnancy.
Topics: Adrenergic beta-Antagonists; Animals; Chronic Disease; Clonidine; Diuretics; Female; Humans; Hydrala | 1985 |
Alpha-adrenergic receptors and blood pressure control.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Drug Ev | 1986 |
Clonidine in abstinence reactions: basic mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Anxiety Disorders; Autonomic Nervous System; Central Nervous Sys | 1986 |
Effects of antihypertensive treatment on cerebral perfusion.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calc | 1987 |
[Management of peroperative hypertensive crises].
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Calcium Channel Blockers; Clonidine; Coronary Dise | 1988 |
[Drug interactions in the treatment of arterial hypertension: an emerging problem].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antide | 1987 |
Therapeutic effect and complication profile of clonidine-beta-blocker combinations.
Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Clonidine; Drug Combinations; Humans; Hyperten | 1988 |
Hypertensive emergencies and urgencies.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; | 1986 |
The comparative effects of clonidine hydrochloride and nifedipine in the treatment of hypertensive crises.
Topics: Clonidine; Emergencies; Humans; Hypertension; Nifedipine | 1988 |
Innovative drug delivery systems in cardiovascular medicine: nifedipine-GITS and clonidine-TTS.
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Clonidine; Delayed-Action Prep | 1987 |
Treatment of hypertensive emergencies and urgencies with oral clonidine loading and titration. A review.
Topics: Blood Pressure; Cardiovascular Diseases; Clonidine; Drug Administration Schedule; Emergencies; Human | 1986 |
Clonidine and guanfacine--comparison of their effects on haemodynamics in hypertension.
Topics: Blood Pressure; Cardiac Output; Clonidine; Epinephrine; Guanfacine; Guanidines; Hemodynamics; Humans | 1985 |
Hypertensive cardiovascular emergencies.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1985 |
[Drug therapy of hypertension].
Topics: Adrenergic beta-Antagonists; Chemical Phenomena; Chemistry; Clonidine; Diuretics; Drug Combinations; | 1973 |
Combination antihypertensive therapy.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamine; Antidepressive Agents; Antih | 1971 |
Choice of antihypertensive drugs for the treatment of hypertension, including hypertensive emergencies.
Topics: Antihypertensive Agents; Bethanechol Compounds; Clonidine; Diazoxide; Diuretics; Emergencies; Ferric | 1974 |
The mechanisms of action of some antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Brain; Bretylium Compounds; Clonidine; Debrisoquin; Diuretics; Gua | 1973 |
Medical management of primary hypertension. 3.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzyl Compounds; Clonidine; Diazoxide; Gangli | 1972 |
[Drug therapy of arterial hypertension].
Topics: Antihypertensive Agents; Arteries; Cardiac Output; Clonidine; Diuretics; Drug Combinations; Guanethi | 1972 |
Recent advances in therapy. Antihypertensive and antibacterial agents.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antihyp | 1972 |
248 trials available for clonidine and Hypertension
| Article | Year |
|---|---|
Clonidine suppression test for a reliable diagnosis of pheochromocytoma: When to use.
Topics: Adrenal Gland Neoplasms; Clonidine; Humans; Hypertension; Metanephrine; Normetanephrine; Paraganglio | 2022 |
Spironolactone Versus Clonidine as a Fourth-Drug Therapy for Resistant Hypertension: The ReHOT Randomized Study (Resistant Hypertension Optimal Treatment).
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Clonidi | 2018 |
Clonidine versus captopril for treatment of postpartum very high blood pressure: study protocol for a randomized controlled trial (CLONCAP).
Topics: Adult; Antihypertensive Agents; Captopril; Clinical Protocols; Clonidine; Epidemiologic Research Des | 2013 |
Resistant hypertension optimal treatment trial: a randomized controlled trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensiv | 2014 |
[Clinical aspects of the using of clopheline in postoperative period in elderly patient with arterial hypertension].
Topics: Age Factors; Antiemetics; Antihypertensive Agents; Child; Child, Preschool; Clonidine; Data Interpre | 2009 |
Efficacy of clonidine in patients with essential hypertension with neurovascular contact of the rostral ventrolateral medulla.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Medull | 2010 |
Is clonidine an adequate alternative to epinephrine as a vasoconstrictor in patients with hypertension?
Topics: Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Antihypertensive Agents; Arrhythmias, Cardiac; | 2012 |
Low-dose (1 microg/kg) clonidine premedication and hypotension after carotid artery surgery.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Analysis of Variance; Antihypertensive Agents; Blood Pre | 2011 |
Therapeutic effects of evening administration of guanabenz and clonidine on morning hypertension: evaluation using home-based blood pressure measurements.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Circadian Rhythm; Cloni | 2003 |
Interactions between leptin and the human sympathetic nervous system.
Topics: Adult; Aging; Antihypertensive Agents; Autonomic Nervous System Diseases; Clonidine; Epinephrine; Fe | 2003 |
Effects of nicardipine and clonidine on cognitive functions and electroencephalography in hypertensive patients.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cognition; Cross | 2002 |
Detrimental effect of blood pressure reduction in the first 24 hours of acute stroke onset.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Female; Humans; Hypert | 2003 |
Leptin and heart sympathetic activity in normotensive obese and non-obese subjects.
Topics: Adipose Tissue; Adrenergic alpha-Agonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihype | 2004 |
Clonidine for the treatment of supine hypertension and pressure natriuresis in autonomic failure.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Autonomic Nervous System; Autonomic Nervous System | 2006 |
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthal | 2007 |
Interaction of clonidine and beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Animals; Atenolol; Blood Pressure; Clinical Trials as Topic; Clo | 1980 |
Clonidine monotherapy in mild hypertension.
Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Benzothiadiazines; Blood Pressure | 1983 |
Transdermal continuous antihypertensive therapy.
Topics: Administration, Topical; Adult; Aged; Clinical Trials as Topic; Clonidine; Diastole; Double-Blind Me | 1984 |
Clonidine in the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clonidine; Diuretics; Drug Therapy, Combination; | 1980 |
[Clonidine-cyclothiazide combination in the therapy of arterial hypertension. Controlled clinical study after oral administration].
Topics: Administration, Oral; Adult; Aged; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Drug Comb | 1983 |
Possible involvement of an endogenous opioid in the antihypertensive effect of clonidine in patients with essential hypertension.
Topics: Adult; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Humans; Hypertension; Middle Aged; | 1982 |
Absence of an effect of mianserin on the actions of clonidine or methyldopa in hypertensive patients.
Topics: Aged; Blood Pressure; Clonidine; Dibenzazepines; Drug Interactions; Female; Heart Rate; Humans; Hype | 1983 |
Naloxone does not antagonize the antihypertensive effect of clonidine in essential hypertension.
Topics: Adult; Blood Pressure; Clonidine; Double-Blind Method; Heart Rate; Humans; Hypertension; Male; Nalox | 1983 |
Failure of naloxone to reduce the clonidine induced reduction of blood pressure and plasma noradrenaline in patients with essential hypertension.
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Naloxone; Norepin | 1983 |
Partial blockade by naloxone of clonidine-induced increase in plasma growth hormone in hypertensive patients.
Topics: Clonidine; Female; Growth Hormone; Humans; Hypertension; Male; Naloxone; Receptors, Opioid | 1984 |
Use of clonidine and propranolol as monotherapy in borderline hypertension.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Double-Bli | 1983 |
[Hemodynamic effects of naloxone during clonidine treatment of patients with essential hypertension].
Topics: Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Antagonism; Female; Hemodynamics; Humans; | 1983 |
Clonidine twice daily in hypertension. Effects of two dosage regimens on blood pressure, side-effects and plasma clonidine concentrations.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Administration Schedule; Fema | 1983 |
Hemodynamic effect of lofexidine with a diuretic in hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Epinephrine; | 1983 |
Reversal by naloxone of the antihypertensive action of clonidine: involvement of the sympathetic nervous system.
Topics: Adult; Blood Pressure; Clonidine; Drug Therapy, Combination; Epinephrine; Heart Rate; Hemodynamics; | 1984 |
Clonidine, acebutolol and their interaction in essential hypertension: effects on blood pressure and the control of water and electrolyte balance.
Topics: Acebutolol; Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Th | 1983 |
Comparison of sustained-release and standard preparations of clonidine in essential hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Delayed-Action Preparations; Double-Blin | 1983 |
Intravenous clonidine in severe hypertension.
Topics: Adult; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertension; Infusions, Parenteral; Mal | 1983 |
Clinical experience with rate-controlled delivery of antihypertensive therapy by a transdermal system.
Topics: Administration, Oral; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination | 1984 |
Transdermal treatment for hypertension.
Topics: Clinical Trials as Topic; Clonidine; Humans; Hypertension | 1984 |
Transdermal administration of clonidine for treatment of high BP.
Topics: Age Factors; Black People; Blood Pressure; Body Weight; Clinical Trials as Topic; Clonidine; Female; | 1984 |
Comparative antihypertensive and endocrinologic effects of clonidine and prazosin in patients with essential hypertension.
Topics: Adult; Blood Pressure; Catecholamines; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-B | 1984 |
Effects of clonidine and guanfacine in essential hypertension.
Topics: Adult; Blood Pressure; Cardiac Output; Clonidine; Guanfacine; Guanidines; Heart Rate; Humans; Hypert | 1984 |
Nifedipine in hypertensive emergencies.
Topics: Adult; Aged; Blood Pressure; Cerebrovascular Circulation; Clinical Trials as Topic; Clonidine; Emerg | 1983 |
[Changes in vigilance after acute and repeated administration of the antihypertensive agents clonidine and prazosin].
Topics: Adult; Attention; Clonidine; Female; Humans; Hypertension; Long-Term Care; Male; Prazosin; Quinazoli | 1983 |
[Long-term treatment with a new antihypertensive drug: flutonidin].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypert | 1983 |
Diuretic therapy for mild hypertension: the "real" cost of treatment.
Topics: Aged; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Cost-Benefit Analysis; Diet; Diuretics | 1984 |
Crossover comparison of moxonidine and clonidine in mild to moderate hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Body Weight; Clonidine; Creatine; Double-Blind Metho | 1984 |
Effects of antihypertensive drugs on cognitive function in adolescents.
Topics: Adolescent; Antihypertensive Agents; Clonidine; Cognition; Female; Humans; Hydrochlorothiazide; Hype | 1984 |
Comparison of intramuscularly and intravenously administered clonidine in the treatment of severe hypertension.
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Hypertension; Injections, Intramuscular; Injection | 1983 |
Comparative efficacy and safety of lofexidine and clonidine given alone or concomitantly with hydrochlorothiazide in hypertensive outpatients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Bl | 1982 |
Comparison of sustained-release clonidine and long-acting propranolol in the treatment of hypertension.
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Delayed-Action Preparations; Double-Blind Method; | 1982 |
[Controlled randomized double-blind study for the comparison of the treatment of patients with essential hypertension with homeopathic and with pharmacologically effective drugs].
Topics: Amiloride; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Combinatio | 1982 |
[Computerized automatic management of the therapy of arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Clopamide; Computers; Dihydroergot | 1981 |
The use of clonidine monotherapy in adolescent hypertension.
Topics: Adolescent; Adult; Blood Pressure; Clonidine; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; | 1983 |
R-wave amplitude change during aerobic exercise in hypertensive adolescents after treatment.
Topics: Adolescent; Adult; Aerobiosis; Blood Pressure; Clonidine; Electrocardiography; Exercise Test; Female | 1983 |
Effects of low-dose antihypertensive therapy in elderly patients with predominant systolic hypertension.
Topics: Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension; Male; Midd | 1983 |
Lofexidine, a new, antihypertensive imidazoline derivative. Clinical profile of action with single-drug treatment and in combination with hydrochlorothiazide.
Topics: Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Clonidine; Drug Combinations; Fema | 1982 |
Relationship of psychological factors to failure of antihypertensive drug treatment.
Topics: Adult; Antihypertensive Agents; Bethanidine; Clonidine; Female; Humans; Hypertension; Male; Methyldo | 1981 |
Clinical trial of xipamide in the treatment of hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Diuretics; D | 1980 |
Blood pressure response to a single daily dose of a clonidine-chlorthalidone combination.
Topics: Adolescent; Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug C | 1980 |
Antihypertensive effect of guanfacine: a double-blind cross-over trial compared with clonidine.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as To | 1980 |
Comparison of guanfacine and clonidine as antihypertensive agents.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Female; Guanfacine; Guanidines; Humans; Hyperten | 1980 |
Hypotensive effect of guanfacine in essential hypertension: a comparison with clonidine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Guanfacine; Gua | 1980 |
[Clinical and experimental study of the hemodynamic effect of gemiton].
Topics: Adolescent; Adult; Aged; Animals; Blood Pressure; Blood Volume; Cats; Clinical Trials as Topic; Clon | 1980 |
Comparison of guanabenz and clonidine in hypertensive patients.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Guanabenz; | 1980 |
[Duration of effectiveness of clonidine-depot: a double-blind trial (author's transl)].
Topics: Aged; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Heart Rate; Humans; Hyperten | 1980 |
[Treatment of sclerotic systolic hypertension].
Topics: Aged; Alkaloids; Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Clonidine; Dru | 1980 |
[Guanfacine: controlled clinical study in arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Female; Guanidines; Human | 1980 |
[A new antihypertensive agent used in a clinical setting].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Bl | 1980 |
Evaluation of guanfacine and clonidine in essential hypertension: a single-blind crossover study.
Topics: Blood Pressure; Clinical Trials as Topic; Clonidine; Guanfacine; Guanidines; Humans; Hypertension; P | 1980 |
Long-term clonidine effects on autonomic function in essential hypertensive man.
Topics: Adult; Blood Pressure; Catecholamines; Clonidine; Heart Rate; Hemodynamics; Humans; Hypertension; Ma | 1981 |
Changes in blood pressure, plasma catecholamines and plasma renin activity during and after treatment with tiamenidine and clonidine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Body Weight; Catecholamines; Clonidine; Epinephrine; | 1981 |
[Nifedipine and essential arterial hypertension refractory to hypotensive therapy: results of a preliminary double-blind study].
Topics: Adult; Aged; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Human | 1981 |
Lofexidine and clonidine in moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Therapy, | 1981 |
Effect of minoxidil on sympathetic nervous activity in clonidine-treated hypertensive patients.
Topics: Adult; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; | 1981 |
[Treatment of diuretic-resistant arterial hypertension - crossed comparative study of verapamil and clonidine].
Topics: Calcium; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertension; Male; Sodium; Verapamil | 1981 |
Usefulness of home BP determination in treating borderline hypertension.
Topics: Adult; Aged; Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Double-Blind Method; | 1982 |
Response of blood pressure and plasma norepinephrine to propranolol, metoprolol and clonidine during isometric and dynamic exercise in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Clonidine; Exercise Test; Female; Heart Rate; Humans; Hypertension; Iso | 1982 |
Antihypertensive effects of lofexidine in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Catecholamines; Clonidine; Dose-Re | 1982 |
Comparison of labetalol and clonidine in hypertension.
Topics: Adult; Clonidine; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle A | 1982 |
Effectiveness of centrally acting drugs and diuretics in adolescent hypertension.
Topics: Adolescent; Blood Pressure; Clonidine; Double-Blind Method; Drug Evaluation; Female; Humans; Hydroch | 1982 |
A clinical study on the prolonged antihypertensive effect of clonidine in a sustained-release capsule formulation.
Topics: Adult; Aged; Blood Pressure; Capsules; Clonidine; Delayed-Action Preparations; Evaluation Studies as | 1980 |
Clonidine-induced hyperglycemia: evidence against a growth hormone-mediated effect.
Topics: Adult; Blood Glucose; Blood Pressure; Clonidine; Female; Growth Hormone; Humans; Hypertension; Male; | 1980 |
Treatment of hypertensive out-patients with a sustained-release dosage form of clonidine: a comparison with standard tablet therapy and long-term follow-up study.
Topics: Adult; Aged; Clonidine; Delayed-Action Preparations; Female; Follow-Up Studies; Humans; Hypertension | 1980 |
Effects of clonidine on plasma catecholamines and neuropeptide Y in hypertensive patients at rest and during stress.
Topics: Adult; Catecholamines; Clonidine; Cold Temperature; Double-Blind Method; Epinephrine; Female; Humans | 1993 |
Comparative effects of atenolol and clonidine on polygraphically recorded sleep in hypertensive men: a randomized, double-blind, crossover study.
Topics: Adolescent; Adult; Atenolol; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Hum | 1995 |
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Hea | 1994 |
Oral clonidine premedication attenuates the hypertensive response to ketamine.
Topics: Administration, Oral; Adolescent; Adult; Anesthesia, Intravenous; Blood Pressure; Clonidine; Female; | 1994 |
Acute effects of urapidil on left ventricular function in hypertensive patients: comparison with clonidine using radionuclide angiography.
Topics: Adrenergic alpha-Antagonists; Aged; Clonidine; Double-Blind Method; Heart; Hemodynamics; Humans; Hyp | 1994 |
Clonidine and lidocaine inhibition of isoflurane-induced tachycardia in humans.
Topics: Administration, Topical; Adult; Anesthesia, Inhalation; Clonidine; Dose-Response Relationship, Drug; | 1994 |
Efficacy and safety of two different galenic formulations of a transdermal clonidine system in the treatment of hypertension.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; | 1993 |
One year efficacy and tolerability of clonidine administered by the transdermal route in patients with mild to moderate essential hypertension--a multicentre open label study. The Antihypertensive Patch Italian Study (APIS) Investigators.
Topics: Administration, Cutaneous; Adult; Blood Pressure; Clonidine; Drug Eruptions; Female; Heart Rate; Hum | 1993 |
Long-term (5 year) experience with transdermal clonidine in the treatment of mild to moderate hypertension.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; | 1993 |
Transdermal clonidine as an adjunct to nifedipine-GITS therapy in patients with mild-to-moderate hypertension.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Chemotherapy, Adjuvant; Clonidine; Female; H | 1993 |
Comparisons of tetracaine spinal anesthesia with clonidine or phenylephrine in normotensive and hypertensive humans.
Topics: Adult; Aged; Anesthesia, Spinal; Blood Pressure; Clonidine; Female; Hemodynamics; Humans; Hypertensi | 1994 |
The cardiovascular response to ketamine: the effects of clonidine and lignocaine.
Topics: Adult; Aged; Clonidine; Double-Blind Method; Female; Humans; Hypertension; Ketamine; Lidocaine; Male | 1993 |
Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Age Factors; Aged; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Captopril; Cloni | 1993 |
Indapamide regresses, but transdermal clonidine does not regress, left ventricular hypertrophy in hypertensive diabetic patients.
Topics: Administration, Cutaneous; Adult; Aged; Antihypertensive Agents; Clonidine; Cross-Over Studies; Diab | 1996 |
Transdermal clonidine therapy and blood pressure nocturnal fall in mild hypertensive male subjects.
Topics: Administration, Cutaneous; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Clonidine; Hum | 1997 |
Effect of single-drug therapy on reduction of left ventricular mass in mild to moderate hypertension: comparison of six antihypertensive agents. The Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhib | 1997 |
Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients.
Topics: Adult; Aged; Blood Glucose; Clonidine; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephr | 1997 |
Hemodynamic and metabolic effects of transdermal clonidine in patients with hypertension and non-insulin-dependent diabetes mellitus.
Topics: Administration, Cutaneous; Adult; Aged; Albuminuria; Blood Glucose; Clonidine; Cross-Over Studies; D | 1998 |
Usefulness of transdermal clonidine in hypertensive patients undergoing minor surgical operations.
Topics: Administration, Cutaneous; Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Moni | 1998 |
Effects of clonidine on power spectral analysis of heart rate variability in mild essential hypertension.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Blood Pressure; Clonidine; Female; Heart Ra | 1998 |
Cardiac baroreflex during the postoperative period in patients with hypertension: effect of clonidine.
Topics: Analgesics; Antihypertensive Agents; Baroreflex; Clonidine; Double-Blind Method; Heart Rate; Humans; | 1999 |
Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Captopri | 1999 |
Clonidine and cardiac surgery: haemodynamic and metabolic effects, myocardial ischaemia and recovery.
Topics: Adrenergic alpha-Agonists; Aged; Anesthetics, Intravenous; Clonidine; Coronary Artery Bypass; Creati | 1999 |
The effects of clonidine on sensitivity to phenylephrine and nitroprusside in patients with essential hypertension recovering from surgery.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Double-B | 1999 |
Alpha 2-agonist versus alpha 1-antagonist in mild-to-moderate hypertension: comparison of transdermal clonidine and terazosin monotherapies.
Topics: Administration, Cutaneous; Administration, Oral; Adrenergic alpha-1 Receptor Antagonists; Adrenergic | 1997 |
Clinical experience with transdermal clonidine in African-American and Hispanic-American patients with hypertension: evaluation from a 12-week prospective, open-label clinical trial in community-based clinics.
Topics: Administration, Cutaneous; Antihypertensive Agents; Black People; Clonidine; Community Health Servic | 1999 |
[Adverse hemodynamic changes during laparoscopic cholecystectomy and their possible suppression with clonidine premedication. Comparison with intravenous and intramuscular premedication].
Topics: Adrenergic alpha-Agonists; Adult; Aged; Antihypertensive Agents; Cholecystectomy, Laparoscopic; Clon | 1999 |
Effects of menstrual cycle and race on peripheral vascular alpha-adrenergic responsiveness.
Topics: Adrenergic alpha-Agonists; Adult; Antihypertensive Agents; Black People; Blood Pressure; Clonidine; | 2000 |
Influence of intravenous clonidine pretreatment on anesthetic requirements during bispectral EEG-guided sevoflurane anesthesia.
Topics: Adolescent; Adult; Aged; Anesthesia, Inhalation; Anesthetics, Inhalation; Anesthetics, Local; Bupiva | 2000 |
[Diovan effectiveness in combined treatment of severe arterial hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bloo | 2000 |
Acute effect of clonidine on left ventricular pressure-volume relation in hypertensive patients with diastolic heart dysfunction.
Topics: Aged; Blood Pressure; Blood Volume; Clonidine; Diastole; Female; Humans; Hypertension; Male; Middle | 2001 |
Autoregulated glomerular filtration rate during candesartan treatment in hypertensive type 2 diabetic patients.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; | 2001 |
Pulse pressure changes with six classes of antihypertensive agents in a randomized, controlled trial.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Clonidine; Diastole; Dilt | 2001 |
Changing concepts in the management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Animals; Benzothiadiazines; Clinical Trials as Topic; Clonidine; | 1975 |
Relationship between clonidine kinetics and its blood pressure effects.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; | 1979 |
[Clonidine in the treatment of hypertension].
Topics: Chlorothiazide; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Female; Humans; Hype | 1977 |
[Treatment of the hypertensive syndrome with hemiton and isobarin in certain diseases of pregnant women].
Topics: Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Guanethidine; Humans; | 1977 |
A comparative trial of clonidine, propranolol and placebo in the treatment of moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Clonidine; Double-Blind Method; | 1977 |
Antihypertensive effect of N-amidino-2-(2,6-dichlorophenyl) acetamide hydrochloride. A double-blind cross-over trial versus clonidine.
Topics: Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Body Weight; Clinical Trials as Topic; C | 1978 |
Effect of clonidine on sympathetic nervous activity in hydralazine-treated hypertensive patients.
Topics: Adult; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 1978 |
Antihypertensive drug combinations: prazosin, hydrochlorothiazide and clonidine.
Topics: Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Drug Combinations; Drug Evaluatio | 1977 |
Prazosin and clonidine for moderately severe hypertension.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Therapy, Comb | 1978 |
[Use of clofelin for arresting hypertensive crises].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Diastole; Drug Evaluation; Emergen | 1978 |
[Clinical trial of the preparation clofazolin used intravenously].
Topics: Adolescent; Adult; Aged; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Clonidine; Drug | 1978 |
[Clinical experiences in antihypertensive treatment with guanabenz or clonidine in combination with thiazide].
Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Diuretics; Drug Therapy, Combination; | 1978 |
Evaluation of the efficacy and safety of guanabenz versus clonidine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Evaluation | 1979 |
[Treatment of hypertension with hemiton and Brinaldix].
Topics: Adult; Clinical Trials as Topic; Clonidine; Clopamide; Drug Evaluation; Humans; Hypertension; Middle | 1979 |
Antihypertensive effects of clonidine.
Topics: Adult; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Clonidine; Diuretics; Double-Bli | 1979 |
[Clofelin treatment of hypertension].
Topics: Adult; Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Humans; Hypertension; Male; Mid | 1979 |
[Effect of a clonidine/cyclothiazine preparation in essential hypertension of light and middle seriousness].
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Combina | 1979 |
Clonidine in primary hypertension: effects on blood pressure, plasma renin activity, plasma and urinary aldosterone.
Topics: Adult; Aldosterone; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertensio | 1977 |
[Clinical trial of a combination preparation of clonidine and cyclothiazide (author's transl)].
Topics: Adult; Benzothiadiazines; Clinical Trials as Topic; Clonidine; Diuretics; Drug Combinations; Female; | 1977 |
Antihypertensive effect of prazosin in combination with methyldopa, clonidine, or propranolol.
Topics: Adult; Blood Pressure; Clonidine; Drug Combinations; Drug Evaluation; Female; Heart Rate; Humans; Hy | 1979 |
Treatment of hypertension successively with a diuretic, clonidine or a beta-blocking agent and hydralazine.
Topics: Benzothiadiazines; Clonidine; Cyclic S-Oxides; Diuretics; Drug Therapy, Combination; Heart Rate; Hum | 1977 |
Abrupt cessation of clonidine administration: a prospective study.
Topics: Adult; Aged; Blood Pressure; Clonidine; Double-Blind Method; Epinephrine; Heart Rate; Hemodynamics; | 1978 |
A sliding intravenous dose schedule for clonidine in hypertensive patients.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Drug A | 1976 |
[Clinical and renal effects of clonidine therapy in arterial hypertension].
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Humans; Hypertension; Kid | 1975 |
The use of clonidine and practolol in the treatment of hypertension.
Topics: Clinical Trials as Topic; Clonidine; Drug Evaluation; Heart Rate; Humans; Hypertension; Male; Middle | 1976 |
[Controlled clinical trial of a new antihypertensive drug: 2,6-dichlorobenzylidene-amino-guanidine acetate].
Topics: Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Guanabenz; Guanidines; Humans; Hyperte | 1976 |
[Study of the hypotensive effect of the combination of a new vasodilator agent (DL 150-IT) with clonidine in the presence of alphamethyldopa].
Topics: Adult; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Combinations; Drug Therapy, Co | 1976 |
Long-term propranolol treatment of resistant arterial hypertension in haemodialysed patients.
Topics: Adult; Clinical Trials as Topic; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combinat | 1975 |
Anti-hypertensive adrenergic-blocking agents: effects on sodium balance, the renin-angiotensin system and haemodynamics.
Topics: Adult; Aldosterone; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Clonidine; Female; Gua | 1975 |
Clonidine and chlorthalidone (combipres) in hypertension.
Topics: Adolescent; Adult; Aged; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Combinations; Dru | 1975 |
Clonidine in treatment of hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertension; Male; Midd | 1975 |
A new technique for safe and effective control of hypertension with intravenous clonidine.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension | 1975 |
A clinical trial of clonidine (Catapres) in private practice.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Fem | 1975 |
[Treatment of hypertension using Trasicor in ambulatory practice. Results of an Austrian field study in 522 patients].
Topics: Adolescent; Adult; Aged; Ambulatory Care; Antihypertensive Agents; Austria; Blood Pressure; Clonidin | 1976 |
Comparison of the effects of pharmacological therapy and a low-sodium diet on mild hypertension.
Topics: Adult; Aged; Chlorthalidone; Clonidine; Humans; Hypertension; Middle Aged; Sodium Chloride | 1976 |
Clonidine in menopausal flushing: a double-blind trial.
Topics: Climacteric; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertension; Middle Aged; Placebo | 1975 |
Combination of clonidine and sotalol in hypertension.
Topics: Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; | 1976 |
The treatment of obese hypertensive black women: a comparative study of chlorthalidone versus clonidine.
Topics: Black People; Blood Pressure; Chlorthalidone; Clonidine; Double-Blind Method; Drug Therapy, Combinat | 1992 |
Peritoneal clearances in hypertensive CAPD patients after oral administration of clonidine, enalapril, and nifedipine.
Topics: Biological Transport; Clonidine; Enalapril; Female; Humans; Hypertension; Kidney Failure, Chronic; M | 1992 |
Oral clonidine pretreatment for haemodynamic stability during craniotomy.
Topics: Administration, Oral; Adult; Clonidine; Craniotomy; Female; Humans; Hypertension; Intraoperative Com | 1992 |
Selective decrement of anionic immunoglobulin clearance after induced renal hemodynamic changes in diabetic patients.
Topics: Adult; Albuminuria; Blood Glucose; Blood Pressure; Captopril; Clonidine; Diabetes Mellitus, Type 1; | 1992 |
Clonidine reduces blood pressure and heart rate oscillations in hypertensive patients.
Topics: Adult; Blood Pressure; Blood Pressure Monitors; Clonidine; Fourier Analysis; Heart Rate; Humans; Hyp | 1991 |
Oral labetalol versus oral clonidine in the emergency treatment of severe hypertension.
Topics: Administration, Oral; Blood Pressure; Clonidine; Diastole; Emergencies; Female; Heart Rate; Humans; | 1992 |
Adrenergic and dopaminergic regulation of circulating beta-endorphin-like immunoreactivity in hypertension.
Topics: Adult; beta-Endorphin; Blood Pressure; Bromocriptine; Clonidine; Dopamine; Heart Rate; Humans; Hyper | 1991 |
[Nifedipine-clonidine combination in essential hypertension. Hemodynamic and neurohumoral findings of the combination in comparison with the effect of the individual substances].
Topics: Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemodynamics; Humans | 1991 |
Home blood pressure monitoring: advantages and limitations.
Topics: Blood Pressure Determination; Clonidine; Coronary Disease; Double-Blind Method; Humans; Hypertension | 1991 |
Skin pretreatment and the use of transdermal clonidine.
Topics: Administration, Cutaneous; Administration, Topical; Adult; Aged; Aluminum Hydroxide; Antacids; Cloni | 1991 |
Therapeutic adherence in the elderly: transdermal clonidine compared to oral verapamil for hypertension.
Topics: Administration, Cutaneous; Administration, Oral; Aged; Blood Pressure; Clonidine; Double-Blind Metho | 1991 |
[Acute reduction of blood pressure: comparative study of nifedipine and clonidine].
Topics: Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; | 1991 |
Effect of chronic clonidine administration on GH secretion in adult human subjects.
Topics: Aged; Clonidine; Female; Growth Hormone; Humans; Hypertension; Insulin-Like Growth Factor I; Male; M | 1991 |
Transdermal and oral clonidine.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Blood Pressure; Clonidine; Double-Blind Meth | 1991 |
Spironolactone and altizide in systemic hypertension: ambulatory multicenter study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Benzothiadiazines; Clonidine; Diuretics | 1990 |
Early blood pressure control improves pregnancy outcome in primigravid women with mild hypertension.
Topics: Adult; Birth Weight; Blood Pressure; Clonidine; Double-Blind Method; Drug Administration Schedule; D | 1991 |
Influence of diuretic therapy on the clonidine suppression test.
Topics: Adult; Amiloride; Clonidine; Double-Blind Method; Drug Combinations; Humans; Hydrochlorothiazide; Hy | 1991 |
[Study of the effectiveness of the clofeline treatment based on the results of its single-dose administration].
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hypertension; Injections, Intravenous | 1991 |
[Clinically significant aspects of the pharmacodynamics of clofelin in hypertension].
Topics: Adult; Aged; Blood Pressure; Clonidine; Drug Administration Schedule; Humans; Hypertension; Middle A | 1990 |
Urapidil versus clonidine. Acute haemodynamic effects during control of intraoperative hypertensive episodes.
Topics: Antihypertensive Agents; Clonidine; Coronary Artery Bypass; Double-Blind Method; Hemodynamics; Human | 1990 |
Low-dose clonidine administration in the treatment of mild or moderate essential hypertension: results from a double-blind placebo-controlled study (Clobass). The Clobass Study Group.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clonidine; Double-Blind Method; Female; Humans; Hyperte | 1990 |
The effects of clonidine hydrochloride versus atenolol monotherapy on serum lipids, lipid subfractions, and apolipoproteins in mild hypertension.
Topics: Adolescent; Adult; Apolipoproteins; Atenolol; Cholesterol; Clonidine; Double-Blind Method; Humans; H | 1990 |
[Clonidine: from the treatment of hypertension to its use in anesthesia. II: Perioperative use].
Topics: Analgesia; Anesthesia; Anesthetics; Animals; Clonidine; Hemodynamics; Humans; Hypertension; Hypotens | 1990 |
CNS side effects of centrally-active antihypertensive agents: a prospective, placebo-controlled study of sleep, mood state, and cognitive and sexual function in hypertensive males.
Topics: Adult; Affect; Aged; Antihypertensive Agents; Central Nervous System Diseases; Clonidine; Cognition; | 1990 |
Effects of transdermal clonidine in young and elderly patients with mild hypertension: evaluation by three noninvasive methods of blood pressure measurement.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Blood Pressure Determination; Clonidine; Der | 1987 |
Hemodynamic and neurohumoral effects of low-dose clonidine in mild to moderate hypertension.
Topics: Adult; Blood Pressure; Clonidine; Epinephrine; Heart Rate; Hemodynamics; Humans; Hypertension; Male; | 1987 |
Effects of clonidine and nifedipine on left ventricular hypertrophy and muscle mass in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clonidine; Echocardiography; Female; Heart; Heart Rate; H | 1987 |
Cerebrospinal fluid norepinephrine levels in essential hypertension: effects of drug treatment and withdrawal.
Topics: Adult; Clonidine; Dopamine; Double-Blind Method; Epinephrine; Humans; Hypertension; Methyldopa; Midd | 1987 |
Randomized, double-blind comparison of transdermal clonidine with oral propranolol.
Topics: Administration, Cutaneous; Administration, Oral; Adolescent; Adult; Aged; Blood Pressure; Clonidine; | 1987 |
Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy, Combination; Emerg | 1988 |
Short- and long-term cerebrovascular effects of nitrendipine in hypertensive patients.
Topics: Adult; Aged; Cerebrovascular Circulation; Chlorthalidone; Clonidine; Female; Humans; Hypertension; M | 1988 |
Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Atenolol; Clonidine; Dermatitis, Contact; Do | 1989 |
Efficacy of four antihypertensive drugs (clonidine, enalapril, nitrendipine, oxprenolol) on stress blood pressure.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Enalapril; | 1989 |
Disparities in blood pressure control under various antihypertensive regimens.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Clonidine; Enalapril; Exercis | 1989 |
[Cicletanine administered with other antihypertensive agents].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidi | 1989 |
Effects of reduction in drugs or dosage after long-term control of systemic hypertension.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Drug Administration Schedule; Follow-U | 1989 |
Practical utility of blood pressure readings obtained by self-determination.
Topics: Adult; Blood Pressure Determination; Clinical Trials as Topic; Clonidine; Double-Blind Method; Femal | 1989 |
The haemodynamic and hormonal responses after clonidine occur independently of sedation in essential hypertension.
Topics: Adult; Aldosterone; Clonidine; Epinephrine; Female; Hemodynamics; Hormones; Humans; Hypertension; Hy | 1989 |
Rapid reduction of severe asymptomatic hypertension. A prospective, controlled trial.
Topics: Administration, Oral; Chlorthalidone; Clonidine; Drug Administration Schedule; Humans; Hypertension; | 1989 |
Effect of clonidine on beta-endorphin, ACTH and cortisol secretion in essential hypertension and obesity.
Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; Circadian Rhythm; Clonidine; Female; Humans; Hyd | 1988 |
Humoral and haemodynamic interactions between clonidine and nifedipine in human essential hypertension.
Topics: Clonidine; Drug Interactions; Hemodynamics; Humans; Hypertension; Nifedipine | 1985 |
Skin reactions to long-term transdermal clonidine.
Topics: Administration, Cutaneous; Clinical Trials as Topic; Clonidine; Drug Eruptions; Humans; Hypertension | 1987 |
A multicenter double-blind comparative study of rilmenidine and clonidine in 333 hypertensive patients.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; | 1988 |
Therapeutic effect and complication profile of clonidine-beta-blocker combinations.
Topics: Adrenergic beta-Antagonists; Cardiovascular Diseases; Clonidine; Drug Combinations; Humans; Hyperten | 1988 |
Oral nifedipine vs oral clonidine in the treatment of urgent hypertension.
Topics: Administration, Oral; Adult; Aged; Clonidine; Double-Blind Method; Emergencies; Female; Humans; Hype | 1989 |
Clinical acceptability of transdermal clonidine: a large-scale evaluation by practitioners.
Topics: Administration, Cutaneous; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Eruptions; Fema | 1986 |
Transdermal antihypertensive therapy: clinical and metabolic considerations.
Topics: Administration, Cutaneous; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Eruptions; Huma | 1986 |
Lipoproteins and metabolic control in hypertensive type II diabetics treated with clonidine.
Topics: Blood Glucose; Clinical Trials as Topic; Clonidine; Diabetes Mellitus, Type 2; Double-Blind Method; | 1988 |
Pathogenesis of hypertension in hemodialysis patients: a pharmacological study.
Topics: Adult; Aged; Blood Pressure; Captopril; Clonidine; Humans; Hypertension; Male; Middle Aged; Nifedipi | 1988 |
[Use of foridon in the treatment of arterial hypertension and hypertension of the lesser circulation].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Syne | 1988 |
Attenuation of pulse rate and blood pressure response to laryngoscopy and tracheal intubation by clonidine.
Topics: Adult; Blood Pressure; Clonidine; Humans; Hypertension; Intubation, Intratracheal; Laryngoscopy; Mid | 1988 |
Impact of antihypertensive therapy on blood pressure reactivity during mental stress.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clonidine; Hemodynamics; Humans; Hypertension; Magne | 1988 |
Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension.
Topics: Administration, Cutaneous; Chlorthalidone; Clinical Trials as Topic; Clonidine; Dermatitis, Contact; | 1988 |
Growth hormone (GH) secretion during nocturnal sleep and after clonidine in patients with essential hypertension.
Topics: Adolescent; Adult; Blood Pressure; Body Weight; Clonidine; Female; Growth Hormone; Humans; Hypertens | 1988 |
Comparison of moxonidine and clonidine HCl in treating patients with hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; C | 1987 |
Transdermal clonidine (Catapres-TTS) monotherapy in the management of mild hypertension in general practice.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Consume | 1987 |
Innovative drug delivery systems in cardiovascular medicine: nifedipine-GITS and clonidine-TTS.
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Clonidine; Delayed-Action Prep | 1987 |
[Low-dose clonidine in moderate arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypert | 1987 |
Comparison of guanfacine versus clonidine for efficacy, safety and occurrence of withdrawal syndrome in step-2 treatment of mild to moderate essential hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug Evaluation; Fe | 1986 |
Treatment of alcohol abstinence symptoms with the alpha 2-agonist clonidine.
Topics: Adult; Alcohol Withdrawal Delirium; Carbamazepine; Chlorprothixene; Clinical Trials as Topic; Clonid | 1986 |
Efficacy of clonidine as transdermal therapeutic system: the international clinical trial experience.
Topics: Administration, Cutaneous; Biological Availability; Blood Pressure; Clinical Trials as Topic; Clonid | 1986 |
Humoral and hemodynamic effects of nitrendipine versus clonidine in patients with essential hypertension.
Topics: Blood Glucose; Clonidine; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Insulin; Male; Mid | 1986 |
Transdermal clonidine in mild hypertension. A randomized, double-blind, placebo-controlled trial.
Topics: Administration, Cutaneous; Adult; Aged; Clinical Trials as Topic; Clonidine; Double-Blind Method; Fe | 1986 |
[Intranasal administration of chlornidine gel in hypertension].
Topics: Administration, Intranasal; Clinical Trials as Topic; Clonidine; Epistaxis; Female; Gels; Humans; Hy | 1987 |
A community-based trial of transdermal antihypertensive therapy with clonidine (Catapres-TTS).
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Dermati | 1986 |
Anesthesia and hypertension: the effect of clonidine on perioperative hemodynamics and isoflurane requirements.
Topics: Anesthesia, General; Clonidine; Female; Hemodynamics; Humans; Hypertension; Intraoperative Period; I | 1987 |
Clonidine and guanfacine in hypertension.
Topics: Adult; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evalua | 1985 |
Antihypertensive effects of urapidil and clonidine: a double-blind cross-over study.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Me | 1985 |
A double blind comparison of indoramin with clonidine in the treatment of moderate to severe essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Electrocardio | 1985 |
A single blind comparison of dihydroergotoxine mesilate and clonidine for treatment of hypertensive emergencies.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Dihydroergotoxine; Drug Tolerance; Emerge | 1985 |
Clonidine hydrochloride--a safe and effective antihypertensive agent in pregnancy.
Topics: Adult; Apgar Score; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female | 1985 |
Long-term experience with lofexidine in the treatment of mild-to-moderate essential hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Double-Blind | 1985 |
Haemodynamic effects of prazosin combinations during dynamic and isometric exercise.
Topics: Adult; Atenolol; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Electrocardiography | 1985 |
Clonidine in mild to moderate hypertension: effects on blood pressure and serum lipoproteins.
Topics: Blood Pressure; Clinical Trials as Topic; Clonidine; Female; Heart Rate; Humans; Hypertension; Lipop | 1985 |
The plasma noradrenaline and growth hormone response to alpha-methyldopa and clonidine in hypertensive subjects.
Topics: Adult; Aged; Blood Pressure; Clonidine; Double-Blind Method; Growth Hormone; Humans; Hypertension; H | 1985 |
Shortcomings of office blood pressures in assessing antihypertensive therapy.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Clonidine; Diuretics; Humans; | 1985 |
Current trends in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Humans; H | 1973 |
Comparison of clonidine and methyldopa in hypertensive patients receiving a diuretic. A double-blind crossover study.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Chemical Phenomena; Chem | 1972 |
Clonidine versus methyldopa. A double blind cross-over study comparing side effects of clonidine and methyldopa administered together with chlorthalidone at a dosage producing the same blood pressure lowering effect.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Consti | 1972 |
[Double blind study with clomidine and reserpine in ambulant therapy of hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Female; Humans; Hypertens | 1972 |
Acute effects of clonidine on central and peripheral haemodynamics and plasma renin activity.
Topics: Adolescent; Adult; Aged; Cardiac Output; Central Venous Pressure; Clinical Trials as Topic; Clonidin | 1972 |
Interaction between clonidine and desipramine in man.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Desipramine; Drug Interactions; Female; | 1973 |
[Depressive effects during treatment with antihypertensive drugs (author's transl)].
Topics: Age Factors; Clinical Trials as Topic; Clonidine; Depression; Dose-Response Relationship, Drug; Drug | 1973 |
Haemodynamic changes in long-term therapy of essential hypertension: a comparative study of diuretics, alpha-methyldopa and clonidine.
Topics: Adult; Cardiac Output; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diuretics; Heart Rate; H | 1973 |
Clonidine in the management of uncontrolled hypertension.
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Female; Follow-Up Studies; Humans; Hypertension; H | 1974 |
[Clinico-experimental evaluation of a new anti-hypertensive agent 2 (2-6 dichlorophenylamino)-imidazoline chlorhydrate].
Topics: Aged; Cardiomyopathies; Clinical Trials as Topic; Clonidine; Diabetic Angiopathies; Drug Evaluation; | 1974 |
[Comparative study of blood pressure, physical complaints and actual emotional condition under clonidine and alpha-methyldopa therapy].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Clonidine; Emotions; Female; Humans; Hypertension; | 1973 |
[Clonidine in the treatment of arterial hypertension. Clinical contribution].
Topics: Clinical Trials as Topic; Clonidine; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension; Ma | 1974 |
[Antihypertensive effects of clonidine and of the clonidine-chlorthalidone combination].
Topics: Adult; Aged; Arteriosclerosis; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; | 1974 |
[Antihypertensive effect of clonidine alone and in combination with chlorthalidone].
Topics: Adult; Chlorthalidone; Clinical Trials as Topic; Clonidine; Drug Evaluation; Drug Synergism; Female; | 1974 |
The Australian National Blood Pressure Study.
Topics: Adult; Aged; Antihypertensive Agents; Australia; Chlorothiazide; Clinical Trials as Topic; Clonidine | 1974 |
[Long-term ambulatory treatment of arterial hypertension with clonidine].
Topics: Adult; Aged; Ambulatory Care; Clinical Trials as Topic; Clonidine; Drug Evaluation; Erectile Dysfunc | 1974 |
[Namestin (Clonidine), 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride in the treatment of essential hypertension (author's transl)].
Topics: Blood Pressure; Chlorides; Clinical Trials as Topic; Clonidine; Creatinine; Drug Evaluation; Fatigue | 1974 |
[Use of clonidine in the therapy of arterial hypertension].
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Drug Tolerance; Female; Follow-Up Studies; Humans; | 1974 |
[French experience with Clonidine].
Topics: Animals; Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Haplorhini; Hemodynamics; Hum | 1972 |
[Clinical trials with clonidine-chlorthalidone, a combined preparation in the treatment of hypertensive diseases].
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Clonidine; Diabetes Mellitus; | 1973 |
Blood pressure crisis following withdrawal of clonidine (Catapres, Catapresan), with special reference to arterial and urinary catecholamine levels, and suggestions for acute management.
Topics: Adult; Blood Pressure; Catecholamines; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; P | 1973 |
The use of clonidine hydrochloride in ambulatory hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Antihypertensive Agents; Chlorthalidone; Cl | 1971 |
1005 other studies available for clonidine and Hypertension
| Article | Year |
|---|---|
4-Substituted semicarbazones of mono- and dichlorobenzaldehydes as antihypertensive agents.
Topics: Animals; Antihypertensive Agents; Benzaldehydes; Dogs; Hypertension; Rats; Semicarbazones; Structure | 1977 |
Synthesis and ocular antihypertensive activity of new imidazolidine derivatives containing a beta-blocking side chain.
Topics: Animals; Antihypertensive Agents; Glaucoma; Guinea Pigs; Hypertension; Imidazoles; Male; Muscle, Smo | 1991 |
5-(1-piperazinyl)-1H-1,2,4-triazol-3-amines as antihypertensive agents.
Topics: Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Diuretics; Dogs; Hypertension; Hype | 1989 |
N2-(4-Substituted-2,6-dichlorophenyl)-N1,N1-dimethylformamidines as antihypertensive and diuretic agents.
Topics: Amidines; Animals; Antihypertensive Agents; Blood Pressure; Chemical Phenomena; Chemistry; Chloroben | 1984 |
2,3-dihydro-3-(1-pyrryl)spiro[benzofuran-2,4'-piperidine]s and 2,3-dihydro-3-(1-pyrryl)spiro[benzofuran-2,3'-pyrrolidine]s: novel antihypertensive agents.
Topics: Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Dogs; Drug Evaluation, Preclinical; F | 1983 |
Antihypertensive activity of 6-arylpyrido[2,3-d]pyrimidin-7-amine derivatives.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Male; Pyridines; Pyrimidines; Rats; | 1981 |
Synthesis and biological evaluation of imidazoline derivatives as potential CNS and CVS agents.
Topics: Animals; Antihypertensive Agents; Central Nervous System Agents; Depression; Female; Hypertension; I | 2020 |
Is Clonidine Contraindicated for the Treatment of Hypertensive Urgencies in Hospitalized Patients?
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hypertension | 2022 |
Safety And Efficacy of Clonidine for Acute Hypertensive Urgency in an Older and Hospitalized Population.
Topics: Aged; Blood Pressure; Clonidine; Cross-Sectional Studies; Female; Humans; Hypertension; Male; Retros | 2022 |
Chiral Luminescent Sensor Eu-BTB@d-Carnitine Applied in the Highly Effective Ratiometric Sensing of Curing Drugs and Biomarkers for Diabetes and Hypertension.
Topics: Biomarkers; Carnitine; Clonidine; Diabetes Mellitus; Europium; Humans; Hypertension; Insulins; Metal | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Blood pressure reduction induced by chronic intracerebroventricular or peroral clonidine administration in rats with salt-dependent or angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Hypertension; Hypotensi | 2022 |
Paroxysmal Hypertension Associated With Presyncope.
Topics: Clonidine; Female; Humans; Hypertension; Low Back Pain; Middle Aged; Muscle Relaxants, Central; Sync | 2019 |
The association between systolic blood pressure reduction during clonidine suppression testing and the decrease in plasma catecholamines and metanephrines.
Topics: Adrenal Gland Neoplasms; Blood Pressure; Catecholamines; Clonidine; Cross-Sectional Studies; Female; | 2020 |
Centrally acting antihypertensives change the psychogenic cardiovascular reactivity.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Clonidine; Hypertension; Ma | 2021 |
The Influence of Xylazine and Clonidine on Lung Ultrasound-Induced Pulmonary Capillary Hemorrhage in Spontaneously Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Capillaries; Clonidine; Hemorrhage; Hypertension; Lung; Male; Rats | 2021 |
Treating Hypertension During Breastfeeding.
Topics: Adult; Antihypertensive Agents; Breast Feeding; Clonidine; Contraindications; Female; Guanfacine; Gu | 2018 |
Co-treatment with clonidine and a GRK2 inhibitor prevented rebound hypertension and endothelial dysfunction after withdrawal in diabetes.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Diabetes Mellitus, Exp | 2018 |
Naloxone reversal of clonidine toxicity: dose, dose, dose.
Topics: Adolescent; Antidotes; Antihypertensive Agents; Child; Child, Preschool; Clonidine; Cohort Studies; | 2018 |
Responsiveness of α2-adrenoceptor/I1-imidazoline receptor in the rostral ventrolateral medulla to cardiovascular regulation is enhanced in conscious spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Blood Pressure Determination; Clonidi | 2019 |
Is GRK2 a new target for cardiovascular disease?
Topics: Cardiovascular Diseases; Clonidine; Diabetes Mellitus; Humans; Hypertension | 2018 |
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension; Monitoring, Physiologic; Spironolactone | 2018 |
Outcomes of minority patients with very severe hypertension (>220/>120 mmHg).
Topics: Adult; Aged; Antihypertensive Agents; Black or African American; Blood Pressure; Clonidine; Female; | 2019 |
Novel stratified medicines approach to manage uncontrolled hypertension due to multiple drug intolerances.
Topics: Administration, Cutaneous; Antihypertensive Agents; Blood Pressure; Clonidine; Disease Management; D | 2018 |
INN Common stem: -onidine.
Topics: Adrenergic alpha-2 Receptor Agonists; Antimalarials; Brimonidine Tartrate; Cinchona Alkaloids; Cloni | 2017 |
Amphetamine and Clonidine Toxicity Resulting in Posterior Reversible Encephalopathy Syndrome.
Topics: Adolescent; Amphetamine; Blood Pressure; Clonidine; Humans; Hypertension; Male; Posterior Leukoencep | 2021 |
Hypertensive Urgency: An Undesirable Complication of a "Male Performance" Herbal Product.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Dietary Supplements; Electrocardiography; Emerge | 2019 |
Tapentadol analgesic interaction with clonidine.
Topics: Analgesics; Antihypertensive Agents; Clonidine; Contraindications; Female; Humans; Hypertension; Mid | 2013 |
Effect of Clonidine (an antihypertensive drug) treatment on oxidative stress markers in the heart of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Biomarkers; Blood Pressure; Clonidine; Heart; Hypert | 2013 |
Dermal exposure to a compounded pain cream resulting in severely elevated clonidine concentration.
Topics: Administration, Cutaneous; Adrenergic alpha-2 Receptor Agonists; Adult; Analgesics; Bradycardia; Clo | 2014 |
Common variants in TGFBR2 and miR-518 genes are associated with hypertension in the Chinese population.
Topics: Aged; Antihypertensive Agents; Asian People; Case-Control Studies; Child; Chrysanthemum; Clonidine; | 2014 |
Hypertensive urgency: an important aetiology of rebound hypertension.
Topics: Adrenergic alpha-2 Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Emergen | 2014 |
Long-term treatment of clonidine, atenolol, amlodipine and dihydrochlorothiazide, but not enalapril, impairs the sexual function in male spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Atenolol; Clonidine; Drug Administration Schedule; Enalapril; Hydr | 2015 |
Intrathecal Clonidine via Lumbar Puncture Decreases Blood Pressure in Patients With Poorly Controlled Hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; | 2015 |
Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system.
Topics: Adrenergic alpha-2 Receptor Agonists; Aminopyridines; Animals; Antihypertensive Agents; Benzamides; | 2015 |
Hypertension in an Adolescent Athlete.
Topics: Adolescent; Arterial Occlusive Diseases; Athletes; Clonidine; Humans; Hypertension; Male; Time Facto | 2016 |
Implementing a Policy and Protocol on Managing Patients With Hypertensive Urgencies.
Topics: Algorithms; Antihypertensive Agents; Clonidine; Cohort Studies; Drug Utilization; Emergency Medical | 2016 |
Poor Choices of Antihypertensive Drugs.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clon | 2016 |
Respiratory, metabolic and hemodynamic effects of clonidine in ventilated patients presenting with withdrawal syndrome.
Topics: Adrenergic alpha-Agonists; Adult; Calorimetry, Indirect; Carbon Dioxide; Clonidine; Electrocardiogra | 2009 |
Effect of clonidine on tyrosine hydroxylase activity in the adrenal medulla and brain of spontaneously hypertensive rats.
Topics: Adrenal Medulla; Adrenergic alpha-Agonists; Animals; Blood Pressure; Blotting, Western; Brain; Catec | 2009 |
Oral contraceptive-induced high blood pressure is prevented by renin-angiotensin suppression in female rats but not by sympathetic nervous system blockade.
Topics: Angiotensin II; Animals; Blood Pressure; Clonidine; Contraceptives, Oral; Dose-Response Relationship | 2008 |
Clonidine pharmacokinetics in pregnancy.
Topics: Adrenergic alpha-Agonists; Adult; Area Under Curve; Clonidine; Female; Half-Life; Humans; Hypertensi | 2009 |
Efficacy of clonidine in a patient with refractory hypertension and chronic renal failure exhibiting neurovascular compression of the rostral ventrolateral medulla.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Creatinine; Drug Resistance; Humans; Hypertensio | 2009 |
Amlodipine-induced myoclonus.
Topics: Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diuretics; Humans; H | 2009 |
High-salt diet increases plasma adiponectin levels independent of blood pressure in hypertensive rats: the role of the renin-angiotensin-aldosterone system.
Topics: Adiponectin; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Clonidine; | 2010 |
Microvascular effects of centrally acting antihypertensive drugs in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Capillaries; Clonidine; Dise | 2010 |
Brain renin-angiotensin system modifies the blood pressure response to intracerebroventricular cadmium in rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; | 2010 |
Clinico-pathologic conference: case 6.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell; | 2009 |
Role of reactive oxygen species in hyperadrenergic hypertension: biochemical, physiological, and pharmacological evidence from targeted ablation of the chromogranin a (Chga) gene.
Topics: Acetophenones; Adrenocortical Hyperfunction; Animals; Antihypertensive Agents; Blood Pressure; Catec | 2010 |
Reduced cardiac contractile force due to sympathovagal dysfunction mediates the additive hypotensive effects of limited-access regimens of ethanol and clonidine in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Clonidine; Drug Interact | 2010 |
Ventricular septal defect in a child with Alport syndrome: a case report.
Topics: Adrenergic alpha-2 Receptor Agonists; Antihypertensive Agents; Clonidine; Collagen Type IV; Disease | 2010 |
Cortical and hippocampal EEG effects of neurotransmitter agonists in spontaneously hypertensive vs. kainate-treated rats.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Baclofen; Clonidine; Disease Models, Animal; | 2011 |
[Acute management at the rising of arterial pressure which is not menacing to a life].
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged; Angiotensin-Converting Enzyme Inhibitors; | 2011 |
Characteristics, practice patterns, and outcomes in patients with acute hypertension: European registry for Studying the Treatment of Acute hyperTension (Euro-STAT).
Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Emergency Service, Hospital | 2011 |
Clonidine utilization trends for Medicaid children.
Topics: Adolescent; Antihypertensive Agents; Attention Deficit Disorder with Hyperactivity; Child; Clonidine | 2012 |
Chronic reduction of nitric oxide level in adult spontaneously hypertensive rats induces aortic stiffness similar to old spontaneously hypertensive rats.
Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Blood Pressure; Clonidine; Hyperten | 2012 |
Effect of clonidine on renal sodium handling in spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Blood Pressure; Clonidine; Creatinine; Dopamine; Hear | 2012 |
Be more vigilant when using clonidine as a vasoconstrictor for local anesthesia!
Topics: Anesthetics, Local; Antihypertensive Agents; Clonidine; Epinephrine; Female; Humans; Hypertension; L | 2012 |
Differential effectiveness of tianeptine, clonidine and amitriptyline in blocking traumatic memory expression, anxiety and hypertension in an animal model of PTSD.
Topics: Adrenocorticotropic Hormone; Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Antihypertens | 2013 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Renal injury caused by intrarenal injection of phenol increases afferent and efferent renal sympathetic nerve activity.
Topics: Adrenergic alpha-Antagonists; Afferent Pathways; Animals; Clonidine; Denervation; Disease Models, An | 2002 |
Clonidine-induced hypertension in a patient with a spinal lesion.
Topics: Adrenergic alpha-Agonists; Adult; Blood Pressure; Chronic Disease; Clonidine; Fructose; Humans; Hype | 2002 |
The role of I(1)-imidazoline and alpha(2)-adrenergic receptors in the modulation of glucose metabolism in the spontaneously hypertensive obese rat model of metabolic syndrome X.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Disease Models, Animal; Female; Glucose | 2003 |
Effects of clonidine on the experimental hypertension by abdominal aortic coarctation in rats.
Topics: Adrenergic alpha-Agonists; Animals; Aortic Coarctation; Blood Pressure; Clonidine; Disease Models, A | 2003 |
[When hypertension becomes an emergency case: lower the blood pressure, but slowly!].
Topics: Administration, Oral; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diagnosis, Diffe | 2003 |
Vasopresin and human hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Female; Humans; Hypertension; Hypothalamo-Hypoph | 2003 |
Acute myocardial infarction as a complication of clonidine withdrawal.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Clonidine; Electrocardiography; Female; Humans; | 2003 |
Role of alpha2-adrenergic receptors and cyclic adenosine monophosphate-dependent protein kinase in the regulation of norepinephrine release in the central nervous system of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Central Nervous System; Clonidine; Cyclic | 2003 |
Hypertension and insulin resistance are not directly related in obese dogs.
Topics: Adrenergic beta-Antagonists; Animals; Aspirin; Atenolol; Blood Glucose; Clonidine; Diet, Sodium-Rest | 2004 |
[Treating high blood pressure in acute stroke].
Topics: Acute Disease; Adrenergic alpha-Agonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve | 2004 |
Delirium tremens--a case study.
Topics: Adult; Alcohol Withdrawal Delirium; Antihypertensive Agents; Chlordiazepoxide; Clonidine; Humans; Hy | 2003 |
[Renal sequelae of sympathetic hyperactivity].
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Ang | 2004 |
[Baroreflex failure after chemodectoma resection].
Topics: Aged; Angiography; Antihypertensive Agents; Autonomic Nervous System Diseases; Baroreflex; Blood Pre | 2004 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Br | 2004 |
[Arterial hypertension intraoperative management in aged patients by different premedication variants].
Topics: Aged; Antihypertensive Agents; Clonidine; Female; Humans; Hypertension; Intraoperative Complications | 2004 |
[Comparative assessment of results of treatment of hipertensive crises with enalapril and clonidine.].
Topics: Clonidine; Enalapril; Humans; Hypertension | 2004 |
Toxic clonidine ingestion in children.
Topics: Analgesics; Bradycardia; Child; Child, Preschool; Clonidine; Coma; Dose-Response Relationship, Drug; | 2005 |
Clonidine--revisited, relived or time for further investigations?
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hypertension | 2005 |
[With diabetes into the mountains. The metabolism derails faster].
Topics: Acclimatization; Antihypertensive Agents; Blood Glucose; Clonidine; Diabetes Mellitus; Heart Disease | 2005 |
Transdermal clonidine: therapeutic considerations.
Topics: Administration, Cutaneous; Clonidine; Drug Eruptions; Humans; Hypertension | 2005 |
Central actions of agmatine in conscious spontaneously hypertensive rats.
Topics: Agmatine; Animals; Antihypertensive Agents; Blood Pressure; Brain; Cardiovascular System; Clonidine; | 2005 |
Hypertensive urgency.
Topics: Aged; Antihypertensive Agents; Blood Pressure Determination; Clonidine; Felodipine; Female; Humans; | 2006 |
Clonidine-induced delirium.
Topics: Adrenergic alpha-Agonists; Clonidine; Delirium; Diagnosis, Differential; Follow-Up Studies; Humans; | 2006 |
Hypertensive emergencies.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clonidine; Diuretics; | 2006 |
[Emergency checklist in hypertensive crisis].
Topics: Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Clonidine; Diuretic | 2006 |
Effects of nine antihypertensive drugs on blood pressure variability in sinoaortic-denervated rats.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium Channel Blockers; Carotid Sinus; Cl | 2006 |
Diltiazem-induced eosinophilic pleural effusion.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Clonidine; Diltiazem; Eosinophilia; Female; Hum | 2007 |
Intermittent clonidine regimen abolishes tolerance to its antihypertensive effect: a spectral study.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Administration Schedule; Drug Tole | 2007 |
A man with labile blood pressure.
Topics: Baroreflex; Blood Pressure; Clonidine; Humans; Hypertension; Hypotension; Male; Middle Aged | 2007 |
High fructose diet increases anterior hypothalamic alpha 2-adrenoceptors responsiveness.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Diet; Fructose; Hypertension; Hypotha | 2007 |
[Acute intoxication with clonidine--a case report].
Topics: Acute Disease; Adult; Antidotes; Bradycardia; Clonidine; Female; Gastric Lavage; Humans; Hypertensio | 2007 |
Clonidine, moxonidine, folic acid, and mecobalamin improve baroreflex function in stroke-prone, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Clonidine; Female; Folic Acid; Hematin | 2007 |
[New methods of chemical and toxicological study of clonidine (Clophelinum)].
Topics: Antihypertensive Agents; Chromatography; Clonidine; Drug-Related Side Effects and Adverse Reactions; | 2007 |
Reduced blood pressure lability during emergence from anaesthesia in rats: a pilot study using clonidine.
Topics: Analgesics; Analysis of Variance; Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; A | 2008 |
Effects of clonidine and superficial cervical plexus block on hemodynamic stability after carotid endarterectomy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cervical Plexus; Clonidine; Endarterectomy, Carotid; | 2008 |
A pheochromocytoma with normal clonidine-suppression test: how difficult the biochemical diagnosis?
Topics: Catecholamines; Clonidine; Diagnosis, Differential; Humans; Hypertension; Male; Metanephrine; Middle | 2008 |
[Clonidine prevents development of hypertension in N (omega)-nitro-L-arginine-treated rats].
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Disease Models, Animal | 2008 |
Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Drug Interactio | 1984 |
Sympathetic nervous system in essential hypertension and antihypertensive response to alpha 2-adrenoceptor stimulation.
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Clonidine; Humans; Hypertension; Norepinephrine; | 1984 |
Beta-endorphin contributes to the antihypertensive effect of clonidine in a subset of patients with essential hypertension.
Topics: Adult; beta-Endorphin; Blood Pressure; Clonidine; Drug Interactions; Endorphins; Heart Rate; Humans; | 1984 |
[Withdrawal syndrome during epidural administration of morphine after stopping treatment with clonidine].
Topics: Aged; Autonomic Nervous System Diseases; Clonidine; Drug Interactions; Epidural Space; Humans; Hyper | 1984 |
Potentials and limitations of angiotensin converting enzyme inhibition in the treatment of hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Clonidine; | 1984 |
[Interaction between clonidine and alpha-blockers (author's transl)].
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dogs; Drug Therapy, Combination; Humans; Hypertens | 1980 |
Errors in the treatment of hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Clonidine; Diuretics; Humans; Hypertension; Methyldopa; | 1980 |
Adverse drug reactions to antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Human | 1980 |
[Effect of hemiton on the microcirculation in arterial hypertension].
Topics: Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Conjunctiva; Female; Humans; Hypertension; Male; | 1980 |
What patients with hypertension should know about their medication.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hydralazine; Hyp | 1980 |
Reversal of clonidine-induced hypotension by beta-adrenoceptor blocking drugs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Female; Heart Ra | 1980 |
beta-Endorphin: possible involvement in the antihypertensive effect of central alpha-receptor activation.
Topics: Adrenergic alpha-Agonists; Animals; Brain Stem; Clonidine; Disease Models, Animal; Endorphins; Hyper | 1981 |
Modern concepts in the drug treatment of arterial hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Capt | 1980 |
Correlations between central hypotensive and peripheral hypertensive effects of structurally dissimilar alpha-adrenoceptor agonists.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Hyp | 1981 |
[Is the combination of beta blockaders and clonidine in antihypertensive therapy dangerous?].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Drug Interactions; Drug Therapy, Co | 1981 |
[Hypertension treatment in the elderly].
Topics: Adrenergic beta-Antagonists; Aged; Blood Glucose; Clonidine; Diuretics; Drug Therapy, Combination; E | 1981 |
Clonidine and prazosin effects in hypernoradrenergic vasodilator-treated and beta-blocker-treated patients.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Body Weight; Clonidine; Diastole; Diuretics; Female; Hu | 1981 |
Abrupt discontinuation of antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bethanidine; Clonidine; Drug Therapy, Combinat | 1981 |
[The present status of treatment of hypertension (author's transl)].
Topics: Adrenergic beta-Antagonists; Captopril; Clonidine; Humans; Hypertension; Nifedipine; Prazosin | 1981 |
[Graduated plan for the treatment of hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Clonidine; Diuretics; Drug Administration Sch | 1981 |
Quantitative aspects of alpha adrenergic effects induced by clonidine-like imidazolidines. I. Central hypotensive and peripheral hypertensive activities.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Central Nervous System; Clonidine; Hypertension; | 1982 |
Lowering of blood pressure in hypertensive rats by SKF 64139 and SKF 72223.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Heart Rate; Hypertension; Isoquino | 1982 |
[Pyrroxan and clofelin effectiveness in hypertensive crises].
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Clonidine; Dioxanes; Dioxins; Drug Evaluation; Emergencie | 1982 |
Abrupt and gradual change from clonidine to beta blockers in hypertension.
Topics: Adrenergic beta-Antagonists; Atenolol; Clonidine; Drug Interactions; Female; Humans; Hypertension; M | 1982 |
Hemodynamic effects of antihypertensive agents.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agent | 1983 |
[Antihypertensive therapy in pregnancy].
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Female; Humans; Hydralazine; Hydro | 1982 |
Reversal of the central hypotensive effect of clonidine by intracisternal curare-like agents.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cisterna Magna; Clonidine; Decamethonium Comp | 1983 |
Simultaneous treatment of hypertension and opiate withdrawal using an alpha 2-adrenergic agonist.
Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Humans; Hypertension; Male; Substance Withdrawal Syndro | 1983 |
Adrenoceptor changes in spontaneous hypertensive rats: a circadian approach.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Brain Stem; Cerebral Cortex; Circadian | 1983 |
[Changes in plasma dopamine beta-hydroxylase activity in patients with hypertension treated with clofelin].
Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Dopamine beta-Hydroxylase; Female; Humans; Hypertension | 1983 |
alpha-Adrenoceptors.
Topics: Adrenergic alpha-Agonists; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; | 1984 |
Sgd 101/75: cardiovascular effects in various animal preparations; interactions with vascular postjunctional alpha 1- and alpha 2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cats; Clonidine; Heart Rate; Hemodynamics; Hyper | 1984 |
Office management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Ambulatory Care; Antihypertensive Agents; Benzothiadiazines; Capt | 1984 |
Use of nifedipine as an adjunct to current antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hype | 1984 |
Use of sympatholytic and vasodilator drugs.
Topics: Adrenergic beta-Antagonists; Clonidine; Diuretics; Drug Therapy, Combination; Guanethidine; Humans; | 1984 |
Effect of clonidine at steady state on blood pressure in spontaneously hypertensive rats. Interaction of various alpha-adrenoceptor antagonists.
Topics: Adrenergic alpha-Antagonists; Animals; Benzimidazoles; Blood Pressure; Clonidine; Dioxanes; Drug Int | 1984 |
Alpha-adrenoceptor- and prostaglandin-mediated modulation of vascular adrenergic neurotransmission in spontaneously hypertensive rats.
Topics: Animals; Autonomic Fibers, Postganglionic; Azepines; Blood Pressure; Clonidine; Dinoprostone; Electr | 1984 |
Antihypertensive activity of tibalosine (CP 804 S) in the rat. Possible involvement of a central alpha 1-adrenergic receptor blockade.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure | 1984 |
Polyarteritis nodosa associated with ulcerative colitis.
Topics: Adolescent; Clonidine; Colectomy; Colitis, Ulcerative; Cyclophosphamide; Humans; Hypertension; Ileos | 1984 |
Alpha 1- and alpha 2-adrenoceptor binding in the Dahl rat model of hypertension.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Brain; Cerebral Cortex; Clonidine; Dioxanes; | 1984 |
Interactions between beta-blockers and clonidine.
Topics: Adrenergic beta-Antagonists; Clonidine; Drug Interactions; Drug Therapy, Combination; Humans; Hypert | 1984 |
[Combined treatment of hypertension patients].
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Evaluation; Drug Ther | 1984 |
Neuropsychiatric manifestations of antihypertensive medications.
Topics: Adrenergic beta-Antagonists; Affective Symptoms; Antihypertensive Agents; Benzothiadiazines; Clonidi | 1983 |
Clonidine: an introduction.
Topics: Antihypertensive Agents; Clonidine; Coronary Disease; Humans; Hypertension; United States | 1980 |
Renal function in long-term minoxidil-treated patients.
Topics: Adult; Blood Pressure; Clonidine; Creatinine; Diuretics; Female; Humans; Hypertension; Hypertension, | 1980 |
An oral calcium antagonist for treatment of hypertensive emergencies.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clonidine; Emergencies; Female; Heart Rate; Humans; | 1982 |
The role of clonidine in hypertensive heart disease. Influence on myocardial contractility and left ventricular afterload.
Topics: Animals; Blood Pressure; Cardiomegaly; Clonidine; Dose-Response Relationship, Drug; Hypertension; Ma | 1983 |
[Effects of the oral administration of clonidine in splits doses in the control of high arterial pressure].
Topics: Administration, Oral; Clonidine; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; | 1984 |
[Effects of long-term treatment with various antihypertensive drugs on the cardiac mass and on the hemodynamics of patients with essential arterial hypertension].
Topics: Adult; Cardiac Output; Cardiomegaly; Clonidine; Echocardiography; Heart; Humans; Hypertension; Methy | 1983 |
Possible role of an endogenous opiate in the cardiovascular effects of central alpha adrenoceptor stimulation in spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; | 1980 |
Enhanced growth hormone response to clonidine in the spontaneously hypertensive rat.
Topics: Animals; Clonidine; Drug Synergism; Growth Hormone; Hypertension; Hypothalamus; Male; Premedication; | 1980 |
Central neurotransmitter receptors in hypertensive rats.
Topics: Aging; Animals; Blood Pressure; Brain; Clonidine; Hypertension; Hypothalamus; Male; Radioligand Assa | 1981 |
Morphine suppresses the blood pressure responses to clonidine withdrawal in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Male; Morphine; Rats; Receptor | 1981 |
Plasma cyclic nucleotides and plasma catecholamines before and after prolonged treatment with clonidine in hypertensive patients.
Topics: Adult; Catecholamines; Clonidine; Cyclic AMP; Cyclic GMP; Female; Glucagon; Humans; Hypertension; Ma | 1981 |
Use of labetalol in hypertensive patients during discontinuation of clonidine therapy.
Topics: Adult; Blood Pressure; Catecholamines; Clonidine; Cyclic AMP; Ethanolamines; Female; Humans; Hyperte | 1981 |
Contribution of cardiovascular reflexes to differences in beta-adrenoceptor-mediated responses in essential hypertension.
Topics: Adolescent; Adult; Aged; Autonomic Nervous System; Blood Pressure; Clonidine; Heart Rate; Humans; Hy | 1981 |
Clonidine and glucose intolerance.
Topics: Blood Glucose; Clonidine; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Humans; | 1982 |
Central alpha-adrenoceptors: clinical applications in cardiovascular disease.
Topics: Animals; Cardiovascular Physiological Phenomena; Clonidine; Humans; Hypertension; Receptors, Adrener | 1983 |
Central alpha-adrenergic control of blood pressure. Effects of clonidine withdrawal.
Topics: Animals; Blood Pressure; Clonidine; Electric Stimulation; Heart Rate; Humans; Hypertension; Hypothal | 1983 |
Relationship of immunoassayable clonidine plasma levels to its pharmacologic action in clinical and experimental hypertension.
Topics: Adult; Animals; Blood Pressure; Clonidine; Half-Life; Humans; Hypertension; Kinetics; Norepinephrine | 1983 |
Hypotensive activity of PAF-acether in rats.
Topics: Animals; Blood Pressure; Calcium; Clonidine; Heart Rate; Hypertension; In Vitro Techniques; Male; Mu | 1982 |
Diurnal rhythm of beta endorphin in normotensive and hypertensive patients: the effect of clonidine.
Topics: beta-Endorphin; Circadian Rhythm; Clonidine; Endorphins; Hemodynamics; Humans; Hypertension | 1983 |
Hypotensive activity of tetrandrine in rats. Investigation into its mode of action.
Topics: Alkaloids; Anesthesia; Animals; Antihypertensive Agents; Azepines; Benzylisoquinolines; Blood Pressu | 1983 |
beta-endorphin acting on the brainstem is involved in the antihypertensive action of clonidine and alpha-methyldopa in rats.
Topics: Animals; beta-Endorphin; Blood Pressure; Clonidine; Desoxycorticosterone; Endorphins; Heart Rate; Hy | 1983 |
Spontaneously hypertensive rats exhibit an enhanced mydriatic response to clonidine. Evidence for enhanced sensitivity of central alpha 2-adrenoceptors.
Topics: Animals; Brain; Clonidine; Hypertension; Male; Pupil; Rats; Rats, Inbred Strains; Receptors, Adrener | 1983 |
[The role of beta endorphin in the antihypertensive action of clonidine, associated with sympathetic tonus decrease, in essential hypertension].
Topics: beta-Endorphin; Clonidine; Endorphins; Heart Rate; Humans; Hypertension; Receptors, Opioid | 1983 |
Effect of antihypertensive therapy on sympathetic nervous system activity in patients with essential hypertension.
Topics: Antihypertensive Agents; Captopril; Clonidine; Guanethidine; Humans; Hydrochlorothiazide; Hypertensi | 1984 |
Characterization of the alpha adrenoceptor-mediated effects and antihypertensive activity of ICI 106270: comparison with clonidine.
Topics: Animals; Antihypertensive Agents; Brain; Clonidine; Dose-Response Relationship, Drug; Guinea Pigs; H | 1984 |
[Studies on the role of the central and peripheral sympathetic nervous system and the renin-aldosterone system on the onset and maintenance of high blood pressure in essential hypertension].
Topics: Adult; Blood Pressure; Clonidine; Cyclic AMP; Humans; Hypertension; Middle Aged; Norepinephrine; Per | 1983 |
Supersensitivity of analgesic responses to alpha 2-adrenergic agonists in genetically hypertensive rats.
Topics: Animals; Clonidine; Hypertension; Male; Naphazoline; Pain; Prazosin; Rats; Rats, Inbred Strains; Rec | 1984 |
Effect of clonidine on blood pressure in chronic one-kidney, one-clip and two-kidney, one-clip hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Female; Hypertension; Norepinephrine; Rats; Rats, Inbred Strains | 1983 |
Cardiovascular hemodynamic interactions between clonidine and minoxidil in hypertensive patients.
Topics: Adult; Blood Pressure; Body Weight; Clonidine; Dopamine beta-Hydroxylase; Drug Interactions; Heart R | 1983 |
Effects of clonidine on sympathetic function.
Topics: Adrenal Gland Neoplasms; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Norepinephrine | 1983 |
The use of centrally acting antihypertensive drugs in patients with renal disease.
Topics: Clonidine; Glomerular Filtration Rate; Humans; Hypertension; Hypertension, Renal; Hypertension, Reno | 1983 |
[The effect of naloxone on plasma renin activity in patients with essential hypertension treated with clonidine].
Topics: Clonidine; Drug Interactions; Humans; Hypertension; Naloxone; Renin | 1983 |
Blood pressure changes in spontaneously hypertensive rats correlate with aortic prostacyclin formation.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Clonidine; Dihydralazine; Epopros | 1983 |
Plasma catecholamines and autonomic nervous system function in patients with early renal insufficiency and hypertension: effect of clonidine.
Topics: Adult; Aged; Aldosterone; Clonidine; Female; Hemodynamics; Humans; Hypertension; Kidney Diseases; Ma | 1984 |
Effect of clonidine therapy on renal hemodynamics in renal transplant hypertension.
Topics: Adult; Clonidine; Hemodynamics; Humans; Hypertension; Kidney Transplantation; Male; Middle Aged; Ren | 1984 |
Guanfacine and clonidine: the effects on adrenal medullary function in spontaneously hypertensive rats.
Topics: Adrenal Glands; Adrenal Medulla; Animals; Blood Pressure; Catecholamines; Clonidine; Guanfacine; Gua | 1984 |
[Clonidine: new aspects of a known principle].
Topics: Cardiovascular Diseases; Clonidine; Heart Failure; Humans; Hypertension | 1983 |
Neurogenic modification of the vulnerability of the blood-brain barrier during acute hypertension in conscious rats.
Topics: Adrenergic Fibers; Animals; Baclofen; Blood-Brain Barrier; Carbon Dioxide; Clonidine; Hydroxydopamin | 1983 |
Disparate effects of methyldopa and clonidine on cardiac mass and haemodynamics in rats.
Topics: Animals; Body Weight; Cardiomegaly; Clonidine; Hemodynamics; Hypertension; Methyldopa; Myocardium; O | 1980 |
Platelet function in hypertension and effect of therapy.
Topics: Adult; Aged; beta-Thromboglobulin; Blood Platelets; Blood Pressure; Clonidine; Heart Rate; Humans; H | 1981 |
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats.
Topics: Animals; Cardiomegaly; Clonidine; Heart; Hemodynamics; Hydralazine; Hypertension; Methyldopa; Organ | 1982 |
Effect of chronic administration of clonidine and propranolol on the myocardium of spontaneously hypertensive rats.
Topics: Animals; Body Water; Cardiomegaly; Clonidine; Glycosaminoglycans; Heart; Hypertension; Muscle Protei | 1982 |
[Clonidine-diuretic combination in patients with essential hypertension. Modification of sympathetic activity and blood pressure as well as the reaction following sudden withdrawal].
Topics: Blood Pressure; Chlorthalidone; Clonidine; Dose-Response Relationship, Drug; Drug Combinations; Epin | 1984 |
Clonidine reduces elevated cerebrospinal fluid catecholamine levels in patients with essential hypertension.
Topics: Adult; Catecholamines; Clonidine; Dopamine; Epinephrine; Female; Humans; Hypertension; Male; Middle | 1984 |
Withdrawal phenomena in subjects with essential hypertension on clonidine or tiamenidine.
Topics: Adult; Blood Pressure; Clonidine; Epinephrine; Humans; Hydrochlorothiazide; Hypertension; Male; Midd | 1984 |
Effect of aging on human plasma growth hormone response to clonidine.
Topics: Adult; Aged; Aging; Clonidine; Female; Growth Hormone; Humans; Hypertension; Male; Middle Aged; Refe | 1984 |
[Ergometric evaluation of the antihypertensive efficacy of clonidine].
Topics: Adult; Clonidine; Exercise Test; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1984 |
Increased incidence of death during warming in hypertensive rats treated with clonidine--possible lung pathology involvement.
Topics: Animals; Blood Pressure; Body Temperature Regulation; Clonidine; Hemorrhage; Hot Temperature; Hypert | 1984 |
[The hypertensive crisis].
Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Dilt | 1984 |
Transdermal clonidine application: long-term results in essential hypertension.
Topics: Administration, Topical; Adult; Clonidine; Dermatitis, Contact; Female; Humans; Hypertension; Male; | 1984 |
Effects of yohimbine on endogenous noradrenaline release from hypothalamus and brainstem slices of spontaneously hypertensive rats.
Topics: Animals; Brain Stem; Clonidine; Electric Stimulation; Hypertension; Hypothalamus; In Vitro Technique | 1984 |
Hypertension associated with clonidine ingestion.
Topics: Accidents; Child, Preschool; Clonidine; Humans; Hypertension; Infant | 1984 |
Changes in cardiac function after effective treatment of hypertensive emergencies with i.v. clonidine.
Topics: Adult; Angiocardiography; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Evaluation; Femal | 1984 |
Opioid involvement in hypertension induced by short-term isolation.
Topics: Adrenalectomy; Animals; Clonidine; Endorphins; Humans; Hypertension; Male; Naloxone; Naltrexone; Psy | 1984 |
The role of TXA2 in hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Clonidine; Di | 1984 |
[Antihypertensive effect of isoteolin in model hypertension].
Topics: Animals; Antihypertensive Agents; Aporphines; Blood Pressure; Cats; Clonidine; Disease Models, Anima | 1984 |
Pheochromocytoma. Current concepts in diagnosis, localization, and management.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Catecholamines; Child; Clonidine; Female; Humans; Hy | 1983 |
[Effect of clonidine on various components of the plasma kinin system in patients with arterial hypertension].
Topics: Adult; Clonidine; Female; Humans; Hypertension; Kallikreins; Kininogens; Male; Middle Aged; Prekalli | 1984 |
Errors in the measurement of blood pressure.
Topics: Blood Pressure Determination; Cardiac Catheterization; Clonidine; False Negative Reactions; Female; | 1983 |
Clonidine through the skin in the treatment of essential hypertension: is it practical?
Topics: Administration, Topical; Adult; Blood Pressure; Clonidine; Drug Hypersensitivity; Drug Therapy, Comb | 1983 |
[Pharmacology of clonidine and its clinical application].
Topics: Animals; Blood Pressure; Brain; Clonidine; Humans; Hypertension; Migraine Disorders; Opioid-Related | 1983 |
[Use of clonidine in hypertension].
Topics: Clonidine; Humans; Hypertension | 1983 |
[Mental changes in hypertensive patients during long-term ambulatory treatment].
Topics: Adult; Ambulatory Care; Antihypertensive Agents; Clonidine; Diuretics; Female; Humans; Hydrochloroth | 1983 |
Interaction of clonidine and labetalol in hypertension.
Topics: Adult; Benzothiadiazines; Blood Pressure; Clonidine; Diuretics; Drug Interactions; Ethanolamines; Fe | 1983 |
Transdermal clonidine for hypertensive patients.
Topics: Administration, Oral; Blood Pressure; Clonidine; Humans; Hypertension; Skin Absorption; Time Factors | 1983 |
Acute hypotensive action of clonidine after intravenous infusion in hypertensive emergencies.
Topics: Adult; Aged; Blood Pressure; Clonidine; Electrocardiography; Emergencies; Female; Heart Rate; Humans | 1983 |
Clonidine in patients with diabetes and mild hypertension.
Topics: Adult; Aged; Blood Pressure; Clonidine; Diabetes Complications; Diabetes Mellitus; Female; Glucose; | 1983 |
Clonidine and prazosin in the treatment of hypertensive outpatients--a preliminary study.
Topics: Adult; Ambulatory Care; Blood Pressure; Clonidine; Drug Therapy, Combination; Drug Tolerance; Electr | 1983 |
Effects of acute and short-term treatment with antihypertensive drugs in sinoaortic denervated rats.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Clonidine; Denervation; Female; Heart Rate; | 1983 |
[Self-control of blood pressure for the purpose of increasing the effectiveness of ambulatory treatment of arterial hypertension].
Topics: Adult; Ambulatory Care; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Follow-Up Stu | 1983 |
A drug interaction between clonidine and enphenamic acid.
Topics: Animals; Clonidine; Dogs; Drug Interactions; Humans; Hypertension; Male; Middle Aged; ortho-Aminoben | 1983 |
[Clonidine transdermal therapeutic system in essential hypertension: effect and tolerance].
Topics: Adult; Body Weight; Clonidine; Dermatitis, Contact; Drug Tolerance; Female; Heart Rate; Humans; Hydr | 1983 |
Effect of clonidine on sympathetic nervous system activity in patients with essential hypertension.
Topics: Adult; Blood Pressure; Clonidine; Dopamine beta-Hydroxylase; Female; Heart Rate; Humans; Hypertensio | 1983 |
[Clonidine in the treatment of hypertensive emergencies].
Topics: Adult; Aged; Blood Pressure; Clonidine; Drug Evaluation; Drug Tolerance; Emergencies; Female; Humans | 1983 |
[Effect of gemiton on carbohydrate metabolic indices].
Topics: Adult; Blood Glucose; Carbohydrates; Carbutamide; Clonidine; Diabetes Mellitus, Type 2; Drug Evaluat | 1984 |
Comparative efficacy and safety of lofexidine and clonidine in mild to moderately severe systemic hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Doubl | 1984 |
Pharmacological, hemodynamic and autonomic nervous system mechanisms responsible for the blood pressure and heart rate lowering effects of pergolide in rats.
Topics: Adrenalectomy; Animals; Antiparkinson Agents; Autonomic Nervous System; Blood Pressure; Clonidine; D | 1984 |
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disea | 1984 |
Relationship between the cardiovascular effects and steady-state kinetics of clonidine in hypertension. Demonstration of a therapeutic window in man.
Topics: Adult; Clonidine; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Kinetics; Male; Middle Age | 1984 |
Amniotic fluid norepinephrine concentration as an indicator of fetal sympathetic nervous activity. Effect of pregnancy complications.
Topics: Amniotic Fluid; Clonidine; Female; Humans; Hypertension; Kidney Diseases; Norepinephrine; Pregnancy; | 1984 |
Paradoxical hypertension from clonidine.
Topics: Clonidine; Diabetic Neuropathies; Humans; Hypertension; Hypotension, Orthostatic; Male | 1984 |
Hypertension after clonidine overdose. A case report.
Topics: Adult; Clonidine; Female; Glomerulonephritis; Humans; Hypertension; Suicide, Attempted | 1984 |
Clonidine and methyldopa--any role for hypertension now?
Topics: Clonidine; Humans; Hypertension; Methyldopa; Substance Withdrawal Syndrome | 1984 |
Effects of clonidine and guanfacine on drinking and ambulation in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Drinking Behavior; Guanfacine; Guanidin | 1982 |
Effect of guanethidine, clonidine and guanfacine on urinary catecholamine excretion in cold-stressed spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Catecholamines; Clonidine; Cold Temperature; Guanethidine; Guanfac | 1982 |
[Antihypertensive effect of guanfacine in rats].
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Consciousness; Decerebrate | 1981 |
[Preparation of patients with arterial hypertension for surgical interventions].
Topics: Acute Kidney Injury; Adolescent; Adult; Clonidine; Female; Hip; Humans; Hypertension; Male; Middle A | 1981 |
ABC of blood pressure reduction.
Topics: Clonidine; Humans; Hypertension; Substance Withdrawal Syndrome | 1981 |
[Efficacy of low clonidine doses in galenic sustained-release preparations. Study with Combipresan 75 perlongettes].
Topics: Adult; Blood Pressure; Chlorthalidone; Clonidine; Delayed-Action Preparations; Drug Combinations; Fe | 1982 |
Effect of phenoxybenzamine on cardiovascular and plasma catecholamine responses to clonidine.
Topics: Blood Pressure; Clonidine; Drug Interactions; Epinephrine; Humans; Hypertension; Norepinephrine; Phe | 1983 |
Blood pressure variability at normal and high blood pressure.
Topics: Adolescent; Adult; Aged; Blood Pressure; Blood Pressure Determination; Clonidine; Heart Rate; Humans | 1983 |
Effects of oral clonidine on baroreflex function in patients with essential hypertension.
Topics: Adult; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Middle Aged; Pressoreceptors; Re | 1983 |
Effects on the renin-angiotensin system of agents acting at central and peripheral adrenergic receptors.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clonidine; Double-Blind Method; Female; Humans; Hypertensi | 1983 |
Hormonal and hemodynamic effects of short- and long-term clonidine therapy in patients with mild-to-moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Clonidine; Female; Glomerular Filtration Rate; Heart Ra | 1983 |
Effects of acute and chronic treatment with clonidine.
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middl | 1983 |
Pharmacokinetics and pharmacodynamics of clonidine in varying states of renal function.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Kidney Failure, Chronic; Kinetics; Male; Middle Aged | 1983 |
Clinical pharmacology of clonidine.
Topics: Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertensio | 1983 |
New aspects of the clinical pharmacology of clonidine.
Topics: Biological Availability; Clonidine; Half-Life; Humans; Hypertension; Kinetics; Radioimmunoassay; Tim | 1983 |
Abrupt cessation of treatment with centrally acting antihypertensive agents. A review.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Humans; Hypertension; Methyldopa; Renin-Angioten | 1983 |
Use of oral clonidine for rapid titration of blood pressure in severe hypertension.
Topics: Administration, Oral; Adult; Ambulatory Care; Blood Pressure; Clonidine; Female; Humans; Hypertensio | 1983 |
Clonidine in the elderly hypertensive. Monotherapy and therapy with a diuretic.
Topics: Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Humans; Hyperten | 1983 |
Combined diuretic and sympatholytic therapy in elderly patients with predominant systolic hypertension.
Topics: Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension; Kidney; Ma | 1983 |
Rebound hypertension after low-dose clonidine withdrawal.
Topics: Clonidine; Female; Humans; Hypertension; Middle Aged; Substance Withdrawal Syndrome | 1983 |
Clonidine raises blood pressure in severe idiopathic orthostatic hypotension.
Topics: Aged; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hypertension; Hypotension, Orthostatic; | 1983 |
Assessment of the interaction between mianserin and centrally-acting antihypertensive drugs.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Dibenzazepines; Double-Blind Method | 1983 |
Hypertensive crisis induced by interaction of clonidine with imipramine.
Topics: Aged; Clonidine; Drug Interactions; Emergencies; Female; Humans; Hypertension; Imipramine; Time Fact | 1983 |
Central and peripheral effects of clonidine on the adrenal medullary function in spontaneously hypertensive rats.
Topics: Adrenal Medulla; Adrenergic Fibers; Animals; Blood Pressure; Catecholamines; Clonidine; Depression, | 1983 |
Clonidine poisoning. A complex problem.
Topics: Apnea; Bradycardia; Child, Preschool; Clonidine; Dopamine; Female; Fluid Therapy; Gastric Lavage; Hu | 1983 |
[Withdrawal syndrome in the treatment of arterial hypertension with clofelin].
Topics: Adult; Aged; Cerebrovascular Disorders; Clonidine; Humans; Hypertension; Male; Middle Aged; Substanc | 1983 |
Clonidine withdrawal complicated by amitriptyline therapy.
Topics: Aged; Amitriptyline; Anxiety; Clonidine; Female; Humans; Hypertension; Intraoperative Care; Methyldo | 1983 |
[Comparative evaluation of the extended hypotensive effect of slow-released clonidine administered alone or in association with a diuretic].
Topics: Adult; Aged; Chlorthalidone; Clonidine; Delayed-Action Preparations; Drug Evaluation; Drug Therapy, | 1983 |
[Central and peripheral actions of clonidine causing changes of the adrenal medullary functions in spontaneously hypertensive rats].
Topics: Action Potentials; Adrenal Glands; Adrenal Medulla; Animals; Catecholamines; Clonidine; Electric Sti | 1983 |
Plasma clonidine levels in hypertension.
Topics: Adult; Blood Pressure; Chromatography, Gas; Clonidine; Dose-Response Relationship, Drug; Female; Hum | 1983 |
Massive clonidine ingestion with hypertension in a 9-month-old infant.
Topics: Accidents, Home; Age Factors; Apnea; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hyperten | 1983 |
Effects of clonidine and heat on thermoregulation in normotensive and hypertensive rats--a preliminary study.
Topics: Animals; Body Temperature Regulation; Clonidine; Hot Temperature; Hypertension; Male; Rats; Rats, In | 1983 |
Animal experiments on the cardiovascular effects of lofexidine.
Topics: Animals; Cats; Clonidine; Dogs; Drug Interactions; Hemodynamics; Hypertension; Hypertension, Renal; | 1982 |
"Clonidine in ... withdrawal ...".
Topics: Clonidine; Humans; Hypertension; Narcotics; Substance Withdrawal Syndrome | 1981 |
[Clinical and experimental study of the effect of obsidan and hemiton on the blood kallikrein-kinin system].
Topics: Adolescent; Adult; Animals; Clonidine; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans | 1982 |
What to watch for with clonidine and methyldopa.
Topics: Clonidine; Drug Interactions; Humans; Hypertension; Methyldopa | 1982 |
The disposition and pharmacokinetics of clonidine in patients--practical consequences.
Topics: Clonidine; Dose-Response Relationship, Drug; Humans; Hypertension; Kinetics | 1980 |
Delirium secondary to clonidine therapy.
Topics: Adult; Clonidine; Delirium; Humans; Hypertension; Male | 1981 |
A lupus erythematosus syndrome induced by clonidine hydrochloride.
Topics: Clonidine; Female; Humans; Hypertension; Lupus Erythematosus, Systemic; Middle Aged | 1981 |
Accelerated acute clonidine withdrawal syndrome during coronary artery bypass surgery. A case report.
Topics: Acute Disease; Clonidine; Coronary Artery Bypass; Humans; Hypertension; Hypotension; Intraoperative | 1981 |
The effect of clonidine on renin and aldosterone of hypertensive patients.
Topics: Adult; Aldosterone; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hydrocortisone; Hypertens | 1980 |
Management of severe hypertension with nifedipine in combination with clonidine or propranolol.
Topics: Adult; Blood Pressure; Clonidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertens | 1980 |
Haemodynamics in hypertensive patients before and during guanfacine treatment.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Output; Clonidine; Female; Guanfacine; Guani | 1980 |
Clinical experience with guanfacine in long-term treatment of hypertension. Part II: adverse reactions to guanfacine.
Topics: Antihypertensive Agents; Body Weight; Clonidine; Dose-Response Relationship, Drug; Drug Administrati | 1980 |
Role of sympathetic nerve inhibition and body sodium-volume state in the antihypertensive action of clonidine in essential hypertension.
Topics: Adult; Aldosterone; Blood Pressure; Clonidine; Epinephrine; Female; Heart Rate; Humans; Hypertension | 1980 |
Effects of abrupt cessation of treatment with clonidine and guanfacine on blood pressure and heart rate in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Epinephrine; Guanfacine; Guanidines; Heart Rate; Hypertension; M | 1981 |
Oral glucose tolerance and insulin response after one week's clonidine treatment in hypertensive patients.
Topics: Adult; Blood Glucose; Clonidine; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hyperten | 1981 |
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Dr | 1981 |
Prolonged clonidine treatment: catecholamines, renin activity and aldosterone following exercise in hypertensives.
Topics: Adult; Aldosterone; Clonidine; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle A | 1981 |
Lofexidine in the treatment of hypertension: a twice-daily versus one-daily dose comparison with 24-hour blood pressure monitoring.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Catecholamines; Clonidine; Drug Administration Sched | 1981 |
Clonidine, a centrally acting sympathetic inhibitor, as monotherapy for mild to moderate hypertension.
Topics: Adult; Blood Volume; Cardiac Output; Clonidine; Epinephrine; Female; Glomerular Filtration Rate; Hea | 1982 |
Plasma clonidine in relation to blood pressure, catecholamines, and renin activity during long-term treatment of hypertension.
Topics: Blood Pressure; Catecholamines; Clonidine; Female; Humans; Hypertension; Kinetics; Male; Pulse; Reni | 1982 |
Guanfacine and clonidine: antihypertensive and withdrawal characteristics after continuous infusion and its interruption in the spontaneously hypertensive and normotensive rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Catheters, Indwelling; Clonidine; Guanfacine; Guan | 1982 |
Inhibition by D 600 of norepinephrine- and clonidine-induced responses of the aortae from normotensive (WKY) and spontaneously hypertensive rats (SHR).
Topics: Animals; Aorta; Calcium Channel Blockers; Clonidine; Gallopamil; Hypertension; In Vitro Techniques; | 1982 |
Clonidine in hypertensive urgencies.
Topics: Clonidine; Emergencies; Humans; Hypertension | 1982 |
Hypertension in older patients: what drugs to use and when.
Topics: Aged; Antihypertensive Agents; Clonidine; Diuretics; Humans; Hypertension; Hypotension, Orthostatic; | 1982 |
Intravenous labetalol in the treatment of severe hypertension.
Topics: Adrenal Gland Neoplasms; Catecholamines; Clonidine; Ethanolamines; Humans; Hypertension; Infusions, | 1982 |
Evidence that alpha-methylepinephrine is an antihypertensive metabolite of alpha-methyldopa.
Topics: Animals; Biotransformation; Blood Pressure; Clonidine; Epinephrine; Heart Rate; Hypertension; Isoqui | 1982 |
Complications of clonidine suppression test for pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Pheochromocytom | 1982 |
Sexual dysfunction associated with oral antihypertensive medication: a critical survey of the literature.
Topics: Antihypertensive Agents; Clonidine; Diuretics; Erectile Dysfunction; Guanethidine; Humans; Hypertens | 1982 |
[Effect of clofelin treatment on external respiration in middle-aged and elderly hypertension patients].
Topics: Aged; Clonidine; Drug Evaluation; Humans; Hypertension; Middle Aged; Respiration | 1982 |
Effect of clonidine and propranolol on venous smooth muscle from spontaneously hypertensive rats.
Topics: Animals; Body Water; Clonidine; Female; Glycosaminoglycans; Hemodynamics; Hypertension; Lipid Metabo | 1982 |
Response of plasma catecholamines and blood pressure to clonidine and to sudden withdrawal of the drug in subjects with essential hypertension.
Topics: Adult; Blood Pressure; Catecholamines; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; No | 1982 |
[Hypertensive circulatory changes in scoliosis surgery during and after the traction phase].
Topics: Anesthesia, General; Arthrodesis; Child; Clonidine; Female; Halothane; Humans; Hypertension; Scolios | 1982 |
[Effect of long-term administration of clonidine on growth hormone secretion in hypertensive diabetics].
Topics: Adult; Blood Glucose; Clonidine; Diabetes Complications; Diabetes Mellitus; Growth Hormone; Humans; | 1982 |
[Plasma catecholamine assay in arterial hypertension].
Topics: Chromatography, High Pressure Liquid; Clonidine; Epinephrine; Humans; Hypertension; Norepinephrine; | 1982 |
Opiate mechanisms in the regulation of the cardiovascular system.
Topics: Animals; Cats; Clonidine; Enkephalins; Hemodynamics; Hypertension; Naloxone; Rats; Rats, Inbred Stra | 1982 |
Cerebral acting maps of hydralazine, clonidine, and alpha-methyldopa in spontaneously hypertensive rats as demonstrated by the 14C-deoxy-D-glucose method.
Topics: Animals; Blood Pressure; Brain; Clonidine; Deoxy Sugars; Deoxyglucose; Hydralazine; Hypertension; Ma | 1982 |
Discontinuation syndrome after continuous infusion of clonidine in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Male; Norepinephrine; Rats; Su | 1981 |
[Effects of long-term administration and cessation of clonidine on blood pressure in spontaneously hypertensive rats (author's transl)].
Topics: Action Potentials; Animals; Blood Pressure; Body Weight; Catecholamines; Clonidine; Eating; Heart Ra | 1980 |
[Short-term clinical trial of a clonidine-cyclothiazide combination in the treatment of arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Combinations; Dr | 1981 |
Growth hormone release in hypertensive adolescents treated with clonidine.
Topics: Adolescent; Adult; Clonidine; Female; Growth Hormone; Humans; Hypertension; Male; Physical Exertion | 1981 |
[Comprehensive use of clofelin and triampur compositum in treating hypertension].
Topics: Adult; Antihypertensive Agents; Clonidine; Drug Combinations; Female; Humans; Hydrochlorothiazide; H | 1981 |
Systemic and cardiac hemodynamic interactions between clonidine and minoxidil.
Topics: Adult; Blood Pressure; Body Weight; Clonidine; Female; Heart; Heart Rate; Hemodynamics; Humans; Hype | 1981 |
Thermoregulation in spontaneously hypertensive rats: effects of antihypertensive treatments.
Topics: Animals; Antihypertensive Agents; Body Temperature Regulation; Chlorothiazide; Clonidine; Hydralazin | 1981 |
Oral clonidine loading in hypertensive urgencies.
Topics: Administration, Oral; Adult; Blood Pressure; Clonidine; Emergencies; Female; Humans; Hypertension; M | 1981 |
Post carotid endarterectomy hypertension: clonidine therapy.
Topics: Carotid Arteries; Clonidine; Endarterectomy; Humans; Hypertension; Postoperative Complications | 1981 |
Effect of chronic administration of clonidine, propranolol and alpha-methyldopa on extensibility and biochemical properties of the veins in renal and spontaneous hypertension.
Topics: Adipose Tissue; Animals; Antihypertensive Agents; Body Water; Clonidine; DNA; Elasticity; Female; He | 1981 |
[Clofelin therapy of hypertensive crises].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Evaluation; Female; Humans; Hy | 1981 |
[Delayed-action clonidine capsules in the therapy of arterial hypertension].
Topics: Capsules; Clonidine; Delayed-Action Preparations; Humans; Hypertension | 1981 |
[Effect of antihypertensives on the activity of lipoprotein lipase of cardiac tissue in rabbits, and normotonic and spontaneously hypertensive rats].
Topics: Animals; Catecholamines; Clonidine; Dopamine; Hypertension; Lipoprotein Lipase; Male; Myocardium; Ra | 1980 |
Effect of antihypertensive therapy on plasma catecholamines in renal failure patients.
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension; Kidney Failure, Chronic; Methyldopa; Middl | 1981 |
Hyperadrenergic hypomania consequent to the abrupt cessation of clonidine.
Topics: Affective Disorders, Psychotic; Aged; Autonomic Nervous System Diseases; Bipolar Disorder; Clonidine | 1981 |
[Antihypertensive activity of minoxidil, hydralazine, prazosin, phentolamine and clonidine in spontaneously hypertensive rats. Comparison with therapeutic dosages].
Topics: Animals; Antihypertensive Agents; Clonidine; Hydralazine; Hypertension; Minoxidil; Phentolamine; Pra | 1981 |
Plasma clonidine concentration and pharmacologic effect.
Topics: Adult; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Ma | 1981 |
[Blocking by naloxone of the antihypertensive effect of clonidine in hypertensive and normotensive animals].
Topics: Animals; Blood Pressure; Cats; Clonidine; Hypertension; Naloxone; Rats | 1981 |
Lack of antagonism in the antihypertensive effects of clonidine and prazosin in man.
Topics: Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; | 1981 |
[Effect of clonidine on the function of adrenal medulla in rats (author's transl)].
Topics: Adrenal Medulla; Animals; Blood Glucose; Blood Pressure; Catecholamines; Clonidine; Hypertension; Ra | 1981 |
[The effect of clonidine on cardiocirculatory function in the treatment of hypertension in pregnancy].
Topics: Adult; Clonidine; Female; Hemodynamics; Humans; Hypertension; Pregnancy; Pregnancy Complications, Ca | 1981 |
Catapres Perlongets in the management of hypertension.
Topics: Adult; Aged; Clonidine; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Aged | 1981 |
Dynamic exercise response in hypertensive adolescent on clonidine therapy: clonidine therapy in adolescent hypertension.
Topics: Adolescent; Blood Pressure; Child; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Myocar | 1980 |
[Clonidine in the management of hypertensive crisis (author's transl)].
Topics: Acute Disease; Aged; Blood Pressure; Cardiac Output; Clonidine; Female; Heart Rate; Humans; Hyperten | 1980 |
Growth hormone secretion in hypertensive patients: evidence for a derangement in central adrenergic function.
Topics: Adult; Clonidine; Female; Growth Hormone; Humans; Hypertension; Levodopa; Male; Middle Aged; Prolact | 1980 |
The effectiveness of clonidine as an antihypertensive in a two-dose regimen.
Topics: Adult; Blood Pressure; Clonidine; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged | 1980 |
Special considerations in treating hypertension in the elderly.
Topics: Aged; Clonidine; Diet, Sodium-Restricted; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension | 1980 |
Rebound hypertension during anaesthesia.
Topics: Aged; Anesthesia, General; Clonidine; Female; Humans; Hypertension; Injections, Intravenous; Substan | 1980 |
Differential effects of alpha-methyldopa, clonidine and hydralazine on norepinephrine and epinephrine synthesizing enzymes in the brainstem nuclei of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Brain Stem; Clonidine; Depression, Chemical; Dopamine beta-Hydroxyla | 1980 |
An acute psychotic episode at the beginning of clonidine therapy.
Topics: Acute Disease; Adult; Clonidine; Female; Humans; Hypertension; Psychoses, Substance-Induced | 1980 |
Clonidine withdrawal, propranolol, and rebound hypertension.
Topics: Clonidine; Drug Administration Schedule; Humans; Hypertension; Propranolol | 1980 |
Influence of clonidine on experimental hypertension induced by cholinergic stimulation.
Topics: Animals; Arecoline; Central Nervous System; Clonidine; Dimethylphenylpiperazinium Iodide; Hypertensi | 1980 |
[Treatment of arterial hypertension in old age].
Topics: Age Factors; Aged; Allopurinol; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Therapy, Co | 1980 |
The involvement of gigantocellular reticular nucleus in clonidine-promoted hypotension and bradycardia in experimentally-induced hypertensive cats.
Topics: Animals; Blood Pressure; Cats; Clonidine; Female; Heart Rate; Hypertension; Injections, Intravenous; | 1980 |
[Treatment of hypertension with clofelin and adelfan-esidrex].
Topics: Adolescent; Adult; Antihypertensive Agents; Clonidine; Dihydralazine; Drug Combinations; Drug Therap | 1980 |
[Medical care of children's hypertension (author's transl)].
Topics: Adolescent; Child; Child, Preschool; Clonidine; Diet, Sodium-Restricted; Diuretics; Humans; Hyperten | 1980 |
Adrenergic mechanisms in selected diseases: arterial hypertension, duodenal ulcer, primary depressive illness, malignant tumors, and ketotic hypoglycemia.
Topics: Adult; Blood Pressure; Child; Clonidine; Depression; Duodenal Ulcer; Epinephrine; Female; Gastrins; | 1980 |
Clonidine hallucinations.
Topics: Adult; Aged; Clonidine; Female; Hallucinations; Humans; Hypertension; Middle Aged | 1980 |
Clonidine-chlorthalidone combination once and twice daily in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clonidine; Drug Administration Schedule; Drug Therapy, | 1980 |
alpha- and beta-adrenoreceptor-mediated control of brain noradrenaline neurons and antihypertensive therapy.
Topics: Action Potentials; Albuterol; Animals; Brain; Clonidine; Dopamine; Hypertension; Locus Coeruleus; Ma | 1980 |
[Alpha-methyldopa and renal function in arterial hypertension].
Topics: Antihypertensive Agents; Clonidine; Dihydralazine; Humans; Hydrochlorothiazide; Hypertension; Hypert | 1980 |
[Luciani-Wenckebach phenomenon during clonidine treatment: a case description].
Topics: Clonidine; Electrocardiography; Heart Block; Heart Conduction System; Humans; Hypertension; Male; Mi | 1980 |
[Treatment of essential arterial hypertension with a combination of clonidine and alpha-methyldopa].
Topics: Adult; Aged; Clonidine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hypertension; Mal | 1980 |
Complications of antihypertensive therapy.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Female; Guanethidine; Humans; Hydr | 1981 |
Acute hypertensive crises.
Topics: Acute Disease; Adult; Aged; Clonidine; Diazoxide; Heart Block; Humans; Hypertension; Injections, Int | 1980 |
Early hemodynamic and humoral effects of lofexidine.
Topics: Adolescent; Adult; Antihypertensive Agents; Catecholamines; Clonidine; Female; Hemodynamics; Humans; | 1981 |
Antihypertensive effects of AT-112, a newly synthesized quinazoline derivative, in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Binding, Competitiv | 1995 |
Evidence for an alpha 1-adrenoceptor subtype mediating adrenergic vasoconstriction in Wistar normotensive and stroke-prone spontaneously hypertensive rat kidney.
Topics: Adrenergic alpha-Antagonists; Amlodipine; Animals; Cerebrovascular Disorders; Clonidine; Dose-Respon | 1994 |
Alpha 1-adrenoceptor subtypes mediating adrenergic vasoconstriction in kidney, one-clip Goldblatt and deoxycorticosterone acetate-salt hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Amlodipine; Animals; Clonidine; Desoxycorticosterone; Disease Models, | 1994 |
Mechanisms of cardiac cell damage due to catecholamines: significance of drugs regulating central sympathetic outflow.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Catecholamines; Clo | 1994 |
Selective antihypertensive action of moxonidine is mediated mainly by I1-imidazoline receptors in the rostral ventrolateral medulla.
Topics: Adrenergic alpha-Antagonists; Affinity Labels; Animals; Antihypertensive Agents; Benzazepines; Benzo | 1994 |
Clonidine-induced bradycardia.
Topics: Antihypertensive Agents; Bradycardia; Clonidine; Humans; Hypertension; Male; Middle Aged | 1995 |
Increased sensitivity to inhibition by nifedipine of responses of the mesenteric artery bed of the SHRSP to noradrenaline is not dependent on alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1995 |
Allergic contact dermatitis from a clonidine transdermal delivery system.
Topics: Administration, Cutaneous; Adult; Clonidine; Dermatitis, Allergic Contact; Female; Humans; Hypertens | 1995 |
[Rubric of good and less good drugs. Clonidine].
Topics: Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension | 1995 |
Absence of tolerance to hypotensive effects of clonidine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Drug Tolerance; Gas Chromatography-Mass Spectrometry; Heart Rate | 1995 |
Alpha 1-adrenoceptor subtypes and inositol phosphates production in heart ventricles of spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Heart Ventricles; Hypertension; Inositol | 1993 |
Effects of captopril and clonidine on resting and stress cardiac performance of left ventricle in spontaneously hypertensive rats.
Topics: Animals; Baroreflex; Blood Pressure; Captopril; Clonidine; Heart Rate; Hypertension; Rats; Rats, Inb | 1994 |
The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Aorta, Thoracic; Clonidine; Dioxanes; Hypertension; In | 1995 |
The mechanism responsible for hypertension in a patient with Guillain-Barré syndrome.
Topics: Adult; Blood Pressure; Circadian Rhythm; Clonidine; Efferent Pathways; Female; Humans; Hypertension; | 1995 |
Neurogenic factors in hypertension: therapeutic implications.
Topics: Adult; Aged; Antihypertensive Agents; Central Nervous System; Clonidine; Hemodynamics; Humans; Hyper | 1994 |
[Transdermal therapy of arterial hypertension: a new approach in the management of hypertensive patients].
Topics: Administration, Cutaneous; Administration, Oral; Blood Pressure; Catecholamines; Clonidine; Heart Ra | 1994 |
Evaluation of the long-lasting antihypertensive action of 7-O-ethylfangchinoline.
Topics: Alkaloids; Animals; Antihypertensive Agents; Benzylisoquinolines; Blood Pressure; Clonidine; Desoxyc | 1994 |
[Therapy of arterial hypertension associated with acute stroke. Current trends and problems].
Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure Monitors; Cerebral Hemorrhage; Cerebrov | 1994 |
[Possible involvement of atrial natriuretic factor and vasopressin in antihypertensive mechanism of clonidine in humans].
Topics: Adult; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Dynorphins; Female; Humans; Hypertensio | 1993 |
Chromogranin A immunoreactivity in human cerebrospinal fluid: properties, relationship to noradrenergic neuronal activity, and variation in neurologic disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amino Acid Sequence; Brain Diseases; Chromogranin A; Chrom | 1993 |
Vasodilator effects of clonidine on the mesenteric arterial beds in normotensive and spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Endothelium, Vascula | 1994 |
Autonomic disturbance in severe tetanus: failure of parenteral clonidine to control blood pressure.
Topics: Aged; Aged, 80 and over; Autonomic Nervous System Diseases; Blood Pressure; Clonidine; Humans; Hyper | 1994 |
Alcohol abolishes the hypotensive effect of clonidine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Ethanol; Hypertension; Male; Rats; Rats, Inbred SHR | 1994 |
Involvement of imidazoline-preferring receptors in regulation of sympathetic tone.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Central Nervous System; Clonidine; D | 1994 |
Sympatholytic effect of captopril in regression of cardiovascular remodeling in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Captopril; Clonidine; Hypertension; Hypertrophy, Left Ventricular; Myocardi | 1994 |
Premedication with oral clonidine for facial rhytidectomy.
Topics: Adult; Aged; Clonidine; Humans; Hypertension; Middle Aged; Premedication; Rhytidoplasty | 1994 |
A novel mechanism of action for hypertension control: moxonidine as a selective I1-imidazoline agonist.
Topics: Adrenal Medulla; Animals; Antihypertensive Agents; Autoradiography; Binding Sites; Blood Pressure; C | 1994 |
Expression of beta-adrenoceptors on circulating mononuclear cells in hypertensives and normotensives before and after reduction of central sympathetic outflow by clonidine.
Topics: Aged; Blood Pressure; Brain; Clonidine; Epinephrine; Female; Growth Hormone; Humans; Hypertension; M | 1994 |
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine | 1993 |
Spectral analysis of blood pressure and heart rate variability in response to stress from air-jet in the Lyon rat.
Topics: Analysis of Variance; Animals; Autonomic Nervous System; Blood Pressure; Clonidine; Heart Rate; Hype | 1994 |
[Experience with the use of clopheline in geriatric anesthesiology].
Topics: Aged; Aged, 80 and over; Anesthesia, Endotracheal; Barbiturates; Bile Duct Diseases; Catecholamines; | 1993 |
[Cardiac effects of GH].
Topics: Acromegaly; Adult; Cardiomegaly; Clonidine; Echocardiography, Doppler; Female; Growth Hormone; Growt | 1993 |
Old wine into new bottles. A critical evaluation of transdermal clonidine in the treatment of hypertension.
Topics: Administration, Cutaneous; Clonidine; Evaluation Studies as Topic; Humans; Hypertension | 1993 |
The sympathetic nervous system and hypertension: mechanisms and treatment.
Topics: Administration, Cutaneous; Clonidine; Drug Eruptions; Humans; Hypertension; Sympathetic Nervous Syst | 1993 |
Clonidine reverses the slowly developing hypertension produced by low doses of angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Clonidine; Hypertension; Male; Rats; Rats, Sprague-Dawley | 1994 |
[The clofelin and nifedipine treatment of hypertensive crises in elderly patients].
Topics: Aged; Chronic Disease; Clonidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertens | 1993 |
Pharmacodynamic interaction of clonidine and muscimol in hypertension.
Topics: Analysis of Variance; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Int | 1993 |
Differential cerebrovascular responsiveness in spontaneously hypertensive rats following antihypertensive treatment with clonidine and verapamil.
Topics: Animals; Blood Pressure; Body Weight; Cerebrovascular Circulation; Clonidine; Heart Rate; Hypertensi | 1993 |
[Changes in plasma neuropeptides before and after clonidine in patients with essential hypertension].
Topics: Adult; Aged; beta-Endorphin; Blood Pressure; Clonidine; Enkephalin, Leucine; Female; Humans; Hyperte | 1993 |
Pheochromocytoma-like catecholamine levels induced by clonidine cessation.
Topics: Catecholamines; Clonidine; Humans; Hypertension; Male; Middle Aged; Pheochromocytoma; Substance With | 1993 |
Transdermal antihypertensive for elderly hypertensives.
Topics: Administration, Cutaneous; Aged; Clonidine; Humans; Hypertension | 1993 |
Dissociation of hypertension and enhanced clonidine-induced antinociception in spontaneously hypertensive rats.
Topics: Analgesics; Animals; Blood Pressure; Clonidine; Guanethidine; Hypertension; Injections, Intraperiton | 1993 |
[Clonidine therapy as cause of visceral lupus erythematosus?].
Topics: Aged; Aged, 80 and over; Clonidine; Female; Humans; Hypertension; Lupus Erythematosus, Systemic | 1993 |
Clonidine improves central attenuation of the baroreflex in spontaneously hypertensive rats.
Topics: Adrenergic Fibers; Animals; Aorta; Baroreflex; Blood Pressure; Clonidine; Electric Stimulation; Hear | 1993 |
The diagnosis and treatment of baroreflex failure.
Topics: Adult; Baroreflex; Blood Pressure; Catecholamines; Clonidine; Female; Humans; Hypertension; Male; Mi | 1993 |
Central serotonergic uptake mechanisms in hypertensive rats: effects of clonidine and centhaquin.
Topics: Animals; Binding, Competitive; Blood Pressure; Brain Chemistry; Brain Stem; Cell Membrane; Cerebral | 1993 |
Hypotensive action of 5-HT receptor agonists in the vitamin B6-deficient hypertensive rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Cerebral C | 1993 |
Plasma levels of beta-endorphin, leucine enkephalin and arginine vasopressin in patients with essential hypertension and the effects of clonidine.
Topics: Angiotensin II; Antihypertensive Agents; Arginine Vasopressin; beta-Endorphin; Blood Pressure; Cloni | 1995 |
Contribution of the sympathetic nervous system to salt-sensitivity in lifetime captopril-treated spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Hexamethonium; Hypertension; | 1995 |
[An acute pharmacological test in predicting the efficacy of hypotensive therapy].
Topics: Adult; Aged; Antihypertensive Agents; Chronic Disease; Clonidine; Drug Evaluation; Hemodynamics; Hum | 1992 |
Rebound hypertension and withdrawal associated with discontinuation of an infusion of epidural clonidine.
Topics: Adenocarcinoma; Adrenergic alpha-Agonists; Clonidine; Humans; Hypertension; Male; Middle Aged; Pain, | 1996 |
Contractile responses to various inotropic agents in isolated hearts obtained from hypertensive diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
alpha1-Adrenoceptor subtypes mediating antinatriuresis in Wistar and stroke-prone spontaneously hypertensive rats.
Topics: Animals; Clonidine; Diuresis; Hypertension; Male; Natriuresis; Phenylephrine; Piperazines; Rats; Rat | 1995 |
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Azepines; Blood Glucose; Blood Pressure; Brimoni | 1996 |
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium | 1996 |
Drug withdrawal and rebound hypertension: differential action of the central antihypertensive drugs moxonidine and clonidine.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Heart Rate; Hypertension; Imidazoles; R | 1996 |
Contribution of the sympathetic nervous system to hypertensive response to insulin excess in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Ganglion | 1996 |
Antihypertensive effects of a new transdermal delivery system for clonidine in genetic and experimental hypertensive rats.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocker | 1996 |
[Clonidine--potential dependence risk in psychiatric patients?].
Topics: Antihypertensive Agents; Arousal; Clonidine; Dose-Response Relationship, Drug; Euphoria; Female; Hum | 1996 |
Clonidine and electrocardiograms.
Topics: Adult; Child; Clonidine; Drug Interactions; Electrocardiography; Humans; Hypertension; Methylphenida | 1996 |
[A chronobiological approach to correcting disorders of time organization of clofelin hemodynamics in patients with stage II essential hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Clonidine; Female; Follow-Up Studies; Hemodynam | 1996 |
Spontaneously hypertensive rat Y chromosome increases indexes of sympathetic nervous system activity.
Topics: Adrenal Glands; Age Factors; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; | 1997 |
Alpha 1-adrenergic receptor antibodies in patients with primary hypertension.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Anta | 1997 |
Hypotensive effects of a new transdermal delivery system for clonidine (M-5041T) in spontaneously and renal hypertensive rats.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; C | 1995 |
alpha-adrenoceptor subtype in the hypothalamic paraventricular nucleus involved in the regulation of urine production: comparison between Wistar Kyoto and spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dose-Response Relationship, Drug; Hypertension; Male; | 1997 |
Effects of clonidine and flesinoxan on blood pressure variability in conscious spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; B | 1997 |
Clonidine antagonizes pressor effect of N-methyl-D-aspartate in the rostral ventrolateral medulla of rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Blood Pressure; Clonidine; Dose-Respon | 1997 |
Why is the hypotensive effect of clonidine greater in hypertensive rats?
Topics: Animals; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Hindlimb; Hypertensio | 1997 |
Beneficial effects of clonidine in streptozotocin-induced diabetes and DOCA-hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cardiomegaly; Clonidine; Desoxycorticosterone; D | 1997 |
Effects of antihypertensive treatment on vasopressin secretion and on its osmoregulation in moderate hypertension.
Topics: Adult; Antihypertensive Agents; Arginine Vasopressin; Clonidine; Female; Humans; Hypertension; Male; | 1997 |
Renal and blood pressure effects of moxonidine and clonidine in spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Aminoacridines; Angiotensin Receptor Antagonists; Ani | 1997 |
Enhanced antinociception of clonidine in spontaneously hypertensive rats involves a presynaptic noradrenergic mechanism.
Topics: Adrenergic Agents; Animals; Antihypertensive Agents; Benzylamines; Clonidine; Hypertension; In Vitro | 1998 |
Alteration of alpha1-adrenoceptor subtypes in aortas of 12-month-old spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Clonidine; Dioxanes; Hypertension; Indoles; Male; Musc | 1998 |
[Premedication with different groups of hypotensive drugs in preparation of patients with concomitant arterial hypertension to planned surgical treatment].
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Female; Humans; Hypertension; H | 1998 |
[The use of clofelin for the treatment of arterial hypertension and for the anesthesia of labor].
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, Obstetrical; Antihypertensive Agents; Clonidine; Cysti | 1997 |
Quantitative receptor radioautography in the study of receptor-receptor interactions in the nucleus tractus solitarii.
Topics: Angiotensin II; Animals; Autoradiography; Blood Pressure; Clonidine; Epinephrine; Hypertension; Neur | 1998 |
Expectations and the placebo effect in clinical drug trials: why we should not turn a blind eye to unblinding, and other cautionary notes.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Clonidine; Humans; Hypertension; Motivation; Pati | 1998 |
Ethanol selectively counteracts hypotension evoked by central I(1)-imidazoline but not alpha2-adrenergic receptor activation in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Ethanol; Heart Rate; Hypertension; Imidazoline Receptors; | 1998 |
Changes in plasma and urinary norepinephrine following transdermal clonidine in spontaneously hypertensive rats.
Topics: Administration, Cutaneous; Administration, Oral; Adrenergic alpha-Agonists; Animals; Clonidine; Hype | 1998 |
Chronopharmacological dependence of antihypertensive effects of the imidazoline-like drugs in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Circadian Rhythm; Cloni | 1998 |
Effect of moxonidine on blood pressure and sympathetic tone in conscious spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Catecholamines; Clonidine; Heart Rate; Hypertensio | 1998 |
Clonidine overdose in childhood: implications of increased prescribing.
Topics: Adrenergic alpha-Agonists; Attention Deficit Disorder with Hyperactivity; Bradycardia; Child; Child, | 1998 |
Clonidine prevents insulin resistance and hypertension in obese dogs.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Cardiac Output; Clonid | 1999 |
Clinical presentation and management of patients with uncontrolled, severe hypertension: results from a public teaching hospital.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-S | 1999 |
Oral clonidine to control hypertension after head injury.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Aged; Clonidine; Craniocerebral Trauma; Humans; Hyp | 1999 |
Effects of agmatine on the cardiovascular system of spontaneously hypertensive rats.
Topics: Agmatine; Animals; Blood Pressure; Clonidine; Diastole; Dose-Response Relationship, Drug; Heart Rate | 1999 |
[A comparative study of 9 cases of adrenal pheochromocytoma and 11 cases of extra-adrenal pheochromocytoma].
Topics: 3-Iodobenzylguanidine; Abdominal Neoplasms; Adrenal Gland Neoplasms; Adrenergic alpha-Agonists; Adul | 1999 |
Autonomic function in hypertensive patients with neurovascular compression of the ventrolateral medulla oblongata.
Topics: Adult; Aged; Autonomic Nervous System; Baroreflex; Blood Pressure; Circadian Rhythm; Clonidine; Fema | 1999 |
Role of the sympathetic control of vascular resistance in ethanol-clonidine hemodynamic interaction in SHRs.
Topics: Animals; Antihypertensive Agents; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Et | 1999 |
Pheochromocytoma in Italy: a multicentric retrospective study.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Aged, 80 and over; Child; Clonidine; Epinephrine; | 1999 |
[New central agents in the treatment of arterial hypertension].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Antihyp | 1999 |
Vascular areas where clonidine induces vasodilation in hypertensive and normotensive rats.
Topics: Animals; Carotid Arteries; Clonidine; Hypertension; Kidney; Mesenteric Artery, Superior; Rats; Rats, | 1999 |
Sodium intake is increased by social stress and the Y chromosome and reduced by clonidine.
Topics: Animals; Antihypertensive Agents; Appetite; Clonidine; Eating; Female; Food Preferences; Hypertensio | 2000 |
Catecholamine-induced hypertension in lumbosacral paraplegia: five case reports.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Blood Pressure; Catecholamines; Clonidine; Humans; Hyp | 2000 |
Baroreflex activity in hypertensive patients.
Topics: Anesthesia; Antihypertensive Agents; Baroreflex; Clonidine; Heart Rate; Humans; Hypertension | 2000 |
Effect of methyldopa, clonidine, and hydralazine on cardiac mass and haemodynamics in Wistar Kyoto and spontaneously hypertensive rats: an historical account and some follow-up.
Topics: Animals; Bibliometrics; Clonidine; Heart; History, 20th Century; Hydralazine; Hypertension; Methyldo | 2000 |
Hypertensive urgency induced by an interaction of mirtazapine and clonidine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Antidepressive Agents; Antihypertens | 2000 |
NaCl-induced hypertensive rat model of non-insulin-dependent diabetes: role of sympathetic modulation.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agon | 2000 |
Effect of aspirin on the contractility of aortic smooth muscle and the course of blood pressure development in male spontaneously hypertensive rats.
Topics: Animals; Aorta; Arachidonic Acids; Aspirin; Blood Pressure; Calcium; Calcium Signaling; Cell Membran | 1998 |
Vascular compression of the rostral ventrolateral medulla in sympathetic mediated essential hypertension.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Magnetic Resonance Imaging; Male; Medulla Oblongata; | 2000 |
Pre-eclampsia is associated with marked alterations in sleep architecture.
Topics: Adult; Antihypertensive Agents; Clonidine; Electroencephalography; Electrooculography; Female; Human | 2000 |
Acute and chronic sympathoinhibition on carotid artery diameter of spontaneously hypertensive rats: effects of clonidine and flesinoxan.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; A | 2000 |
Recurrent short-lasting headache associated with paroxysmal hypertension: a clonidine-responsive syndrome.
Topics: Acute Disease; Aged; Antihypertensive Agents; Clonidine; Headache; Humans; Hypertension; Male; Middl | 2000 |
Systemic injection with DSP-4 decreases the clonidine hypotension in bicuculline-treated rats.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Benzylamines; Bicuculline; Biogenic Mon | 1999 |
Hypotension following the initiation of tizanidine in a patient treated with an angiotensin converting enzyme inhibitor for chronic hypertension.
Topics: Adrenergic alpha-Agonists; Angiotensin-Converting Enzyme Inhibitors; Child; Clonidine; Drug Interact | 2000 |
Treatment of chronic hypertension with intravenous enalaprilat and transdermal clonidine.
Topics: Administration, Cutaneous; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2001 |
Sodium-induced rise in blood pressure is suppressed by androgen receptor blockade.
Topics: Analysis of Variance; Androgen Antagonists; Androgen Receptor Antagonists; Animals; Blood Pressure; | 2001 |
Gelatin microspheres crosslinked with D,L-glyceraldehyde as a potential drug delivery system: preparation, characterisation, in vitro and in vivo studies.
Topics: Animals; Antihypertensive Agents; Clonidine; Cross-Linking Reagents; Drug Delivery Systems; Excipien | 2001 |
Normalization of blood pressure in a patient with severe orthostatic hypotension and supine hypertension using clonidine.
Topics: Adrenergic alpha-Agonists; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Female; Humans; | 2001 |
Evidence for the involvement of central I1 imidazoline receptor in ethanol counteraction of clonidine hypotension in spontaneously hypertensive rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Age | 2001 |
[Baroreflex failure syndrome: an uncommon case of an extreme blood pressure variability].
Topics: Antihypertensive Agents; Baroreflex; Blood Pressure; Carotid Body Tumor; Clonidine; Follow-Up Studie | 2001 |
Alpha2 -adrenoceptor function in arterial hypertension associated with obesity in dogs fed a high-fat diet.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood | 2002 |
[Drug therapy of hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Clonidine; Diazoxide; Digitalis Glycosi | 1975 |
Rapid clonidine withdrawal with blood pressure overshoot exaggerated by beta-blockade.
Topics: Adrenergic beta-Antagonists; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Mid | 1976 |
The kidney and antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hy | 1976 |
Central noradrenergic control of blood pressure.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cats; Clonidine; Desipramine; Dogs; Drug Interac | 1976 |
The general management of hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Animals; Antihypertensive Agents; Benzothiadiazines; Clonidine; D | 1976 |
Additive effect of beta-adrenergic blockers in combination with vasodilators in lowering blood pressure.
Topics: Adrenergic beta-Antagonists; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Mal | 1976 |
Labetalol (AH5158), a competitive alpha- and beta-receptor blocking drug, in the management of hypertension.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Cloni | 1976 |
Clonidine.
Topics: Adrenergic alpha-Agonists; Blood Pressure; Cardiac Output; Clonidine; Humans; Hypertension | 1977 |
Valsalva vasoconstrictor reflex in human hypertension in after beta-adrenoreceptor blockade in conscious rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardiac Output; Clonidine; Humans; Hypertensio | 1976 |
Management of hypertension.
Topics: Adrenergic alpha-Antagonists; Benzothiadiazines; Clonidine; Diuretics; Ethacrynic Acid; Furosemide; | 1977 |
Blood pressure and heart rate and withdrawal of antihypertensive drugs.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Female | 1977 |
Drug treatment of hypertension.
Topics: Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertensio | 1977 |
The interaction between clonidine and various neuroleptic agents and some benzodiazepine tranquillizers.
Topics: Anesthesia; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Blood Pressure; Cat | 1977 |
Clonidine and the vasodilating beta blocker antihypertensive drug interaction.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Blood Pressure; Clonidine; Drug Interactions; Femal | 1977 |
Some cardiovascular effects of ST-91 and clonidine.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Desipramine; Do | 1977 |
[Hypertension and anesthesia (author's transl)].
Topics: Adrenergic beta-Antagonists; Anesthesia; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazin | 1977 |
[Suppression of the antihypertensive effect of clonidine by the simultaneous intake of a tricyclic antidepressive agent. Practical problem in the treatment of a depressed hypertensive patient].
Topics: Adrenergic beta-Antagonists; Adult; Antidepressive Agents, Tricyclic; Antihypertensive Agents; Clomi | 1977 |
[The orthostatic hypotension in patients treated with antihypertensive drugs (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Antihypertensive Agents; Clonidine; Diuretics; Fema | 1977 |
Long-term use of prazosin in combination or alone for treating hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Clonidine; Drug Therapy, Combination; F | 1977 |
Role of peripheral vascular resistance and reactivity in the interaction between clonidine and imipramine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Hypertension; Imipramine; Male; Rats; Vascular Resistance | 1978 |
Antagonism by mianserin and classical alpha-adrenoceptor blocking drugs of some cardiovascular and behavioral effects of clonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Avoidance Learning; Behavior, Animal; Clonidine; Dibenzazepin | 1978 |
Hypotension and adrenal tyrosine hydroxylase in spontaneously hypertensive rats.
Topics: Adrenal Glands; Animals; Antihypertensive Agents; Clonidine; Dopamine beta-Hydroxylase; Epinephrine; | 1978 |
Abnormal sodium transport in leucocytes from patients with essential hypertension and the effect of treatment.
Topics: Adrenergic beta-Antagonists; Benzothiadiazines; Biological Transport, Active; Blood Pressure; Clonid | 1975 |
Treatment of severe and resistant hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diet, Sodium-Restricted; | 1978 |
[Treatment of arterial hypertension in the aged].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Antihypertensive Agents; Clonidine; Diuretics; Human | 1978 |
[Saralasin in resistant hypertensive crisis (author's transl)].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Clonidine; Female; Furosemide; Glomerulone | 1979 |
Approach to drug therapy for hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzothiadiazines; Clonidine; Diu | 1979 |
Antihypertensive drugs for the aging.
Topics: Aged; Antihypertensive Agents; Clonidine; Ganglionic Blockers; Guanethidine; Humans; Hypertension; M | 1979 |
Differential antihypertensive effects of clonidine in different models of experimental hypertension in rats.
Topics: Animals; Antihypertensive Agents; Clonidine; Desoxycorticosterone; Disease Models, Animal; Hypertens | 1979 |
Haemodynamic effects of systemic administration of clonidine in the anaesthetized spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiac Output; Clonidine; Hemodynamics; Hypertension; Male; Rats; Regional | 1979 |
Steady state plasma concentration of clonidine and its relation to the effects on blood pressure in normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Depression, Chemical; Hypertension; Male; Rats; Time Factors | 1979 |
[The physiological basis of the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Angiotensins; Captopril; Central Nervous System; Clonidine; Humans; Hyp | 1979 |
Review: the significance and management of raised blood pressure in pregnancy.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Chlormethiazole; Clonidine; Diazepam; D | 1979 |
Alterations in myocardial adenylate cyclase in spontaneously hypertensive rats.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Albuterol; Animals; Catecholamines; Clonidine; Glucagon | 1979 |
[Hypotensive drugs].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diuretics; Guanidines; Humans; Hype | 1979 |
Haemodynamic setting of essential hypertension as a guide to management.
Topics: Antihypertensive Agents; Arteries; Blood Pressure; Cardiac Output; Clonidine; Diazoxide; Diuretics; | 1975 |
Some aspects of the management of hypertension. 1. General considerations.
Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clonidine; Dia | 1975 |
Proceedings: The effects of hypothalamic and reflexogenic hypertension on renal and femoral circulation.
Topics: Animals; Antihypertensive Agents; Atropine; Benzimidazoles; Blood Flow Velocity; Carotid Sinus; Clon | 1975 |
Severe arterial hypertension caused by chronical abuse of a topical mineralocorticoid.
Topics: Adult; Aldosterone; Clonidine; Drug Combinations; Drug Therapy, Combination; Female; Fluprednisolone | 1975 |
Letter: Labetalol and clonidine in severe hypertension.
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension | 1976 |
Letter: Clonidine withdrawal.
Topics: Clonidine; Humans; Hypertension; Male; Middle Aged; Substance Withdrawal Syndrome | 1976 |
Letter: Clonidine in severe hypertension.
Topics: Clonidine; Humans; Hypertension | 1976 |
Efficacy of antihypertensive drugs.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Drug Evaluatio | 1976 |
Letter: Clonidine withdrawal and blockade.
Topics: Clonidine; Drug Synergism; Humans; Hypertension; Propranolol | 1976 |
Withdrawal of clonidine.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Pregnancy; Pregnancy Complication | 1977 |
Clonidine withdrawal in hypertension. Changes in blood-pressure and plasma and urinary noradrenaline.
Topics: Adult; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Norep | 1977 |
Clonidine-withdrawal syndrome.
Topics: Clonidine; Humans; Hypertension; Hypertension, Malignant; Nitroprusside; Substance Withdrawal Syndro | 1977 |
Plasma renin and "prorenin" in essential hypertension during sodium depletion, beta-blockade, and reduced arterial pressure.
Topics: Adult; Blood Pressure; Chlorthalidone; Clonidine; Depression, Chemical; Diet, Sodium-Restricted; Dru | 1977 |
Analysis of efficacy of antihypertensive drugs.
Topics: Clonidine; Diastole; Drug Evaluation; Humans; Hypertension; Posture; Propranolol | 1979 |
Problems in the treatment of hypertension.
Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Clonidin | 1979 |
[Pharmacotherapy of hypertension and its significance for the function of the salivary glands (author's transl)].
Topics: Animals; Antihypertensive Agents; Autonomic Nervous System; Clonidine; Guanidines; Hypertension; Mas | 1975 |
[Effect of clonidine on three types of experimental hypertension and on plasma renin activity in dogs].
Topics: Animals; Blood Pressure; Clonidine; Cyanides; Dogs; Female; Hypertension; Renin | 1978 |
Effect of chronic clonidine treatment and its abrupt cessation on mean blood pressure of rats with a normal or an elevated blood pressure.
Topics: Animals; Blood Pressure; Body Weight; Cardiomegaly; Clonidine; Female; Hypertension; Kidney; Organ S | 1979 |
[New concepts on central regulation of the blood pressure. Mode of action of clonidine and alpha-methyl DOPA (author's transl)].
Topics: Animals; Blood Pressure; Clonidine; Humans; Hypertension; Methyldopa; Norepinephrine; Rats; Receptor | 1977 |
Antihypertensive action of clonidine (Catapresan).
Topics: Animals; Blood Pressure; Bradycardia; Brain Stem; Cats; Clonidine; Depression, Chemical; Drug Evalua | 1977 |
Suppression of plasma catecholamines and flushing by clonidine in man.
Topics: Adenoma, Islet Cell; Adult; Blood Pressure; Catecholamines; Clonidine; Diabetes Mellitus; Face; Fema | 1978 |
Evidence for a central alpha-sympathomimetic action of clonidine in the rat.
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Clonidine; Dopamine; Hypertension; Kidn | 1975 |
The effect of clonidine and penbutolol, respectively on catecholamines in blood and urine, plasma renin activity and urinary aldosterone in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Butylamines; Catecholamines; Clonidine; Cyclopentan | 1975 |
[Drug therapy of hypertension in general practice].
Topics: Adrenergic beta-Antagonists; Adult; Clonidine; Diuretics; Humans; Hydralazine; Hypertension; Methyld | 1975 |
Study of renal functions by repeated constant infusion of radiotracers before and after initiation of therapy in hypertension or in diabetes mellitus.
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Clonidine; Diabetes Mellitus; Diazoxide; Huma | 1975 |
Management of hypertension.
Topics: Adrenergic beta-Antagonists; Age Factors; Bethanidine; Clonidine; Debrisoquin; Decision Making; Diur | 1975 |
Pharmacology update: hypotensive agents. Part II: Antiadrenergic agents.
Topics: Antihypertensive Agents; Clonidine; Guanethidine; Hypertension; Methyldopa; Sympatholytics | 1979 |
[Carotid sinus syndrome caused by clonidine].
Topics: Aged; Carotid Sinus; Clonidine; Humans; Hypertension; Male; Middle Aged; Pressoreceptors; Syncope | 1978 |
The use of clonidine by intramuscular injection in the treatment of hypertension.
Topics: Adult; Aged; Clonidine; Female; Humans; Hypertension; Injections, Intramuscular; Male; Middle Aged | 1977 |
"CBE studies in hypertensive patients during acute controlled hypotension and after a period of medical treatment. Pathophysiological and clinical correlations".
Topics: Cerebrovascular Circulation; Clonidine; Humans; Hypertension | 1977 |
Drug treatment of mild hypertension: adverse consequences.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Diuretics; Drug Interactions; Female; Guaneth | 1978 |
A physiological basis for the treatment of essential hypertension.
Topics: Aldosterone; Clonidine; Diuretics; Humans; Hypertension; Propranolol; Renin; Sodium | 1978 |
[Clinical and biological manifestations following the interruption of prolonged treatment with clonidine].
Topics: Adult; Aged; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Female; Heart | 1977 |
Clonidine withdrawal syndrome in Tanzania--a substantial risk.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Long-Term Care; Male; Middle Aged; Substance Withdra | 1978 |
[Poisoning with clonidine and severe arterial hypertension].
Topics: Clonidine; Humans; Hypertension; Time Factors; Tolazoline | 1979 |
Propranolol and newer antihypertensive drugs in the management of hypertension.
Topics: Angiotensin II; Clonidine; Diuretics; Humans; Hypertension; Minoxidil; Prazosin; Propranolol; Sarala | 1979 |
Clonidine--a centrally acting antihypertensive drug.
Topics: Blood Pressure; Clonidine; Hemodynamics; Humans; Hypertension; Kidney; Renin | 1979 |
Clonidine and propranolol paradoxical hypertension.
Topics: Clonidine; Drug Interactions; Humans; Hypertension; Male; Middle Aged; Propranolol | 1979 |
Delirium associated with combined fluphenazine-clonidine therapy.
Topics: Adult; Clonidine; Delirium; Drug Therapy, Combination; Fluphenazine; Humans; Hypertension; Male; Psy | 1979 |
[Pharmacological properties and clinical use of clofelin].
Topics: Animals; Blood Pressure; Clonidine; Humans; Hypertension | 1979 |
Preoperative and postoperative use of clonidine with neurolept anaesthesia.
Topics: Administration, Oral; Blood Circulation; Clonidine; Epinephrine; Female; Homeostasis; Humans; Hypert | 1979 |
Failure of labetalol to prevent hypertension due to clonidine withdrawal.
Topics: Adult; Clonidine; Drug Combinations; Ethanolamines; Female; Humans; Hypertension; Labetalol; Substan | 1979 |
Effect of intravenous or intracisternal clonidine and propranolol on plasma renin. Activity in hypertensive dogs.
Topics: Animals; Cisterna Magna; Clonidine; Dogs; Drug Evaluation; Female; Hypertension; Injections, Intrave | 1979 |
Fatal rebound hypertension after abrupt withdrawal of clonidine and propranolol.
Topics: Clonidine; Humans; Hypertension; Male; Middle Aged; Propranolol; Substance Withdrawal Syndrome | 1979 |
Abrupt discontinuation of clonidine therapy.
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Substance Withdra | 1979 |
Reduced renovascular resistance by clonidine.
Topics: Adult; Clonidine; Creatinine; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; | 1979 |
The therapeutic value of clonidine in patients with coronary heart disease.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Clonidine; Coronary Disease; Drug Tolerance; Female; Humans; | 1979 |
Influence of clonidine, alpha-methyldopa and hydralazine on noradrenergic and adrenergic neuronal activities in brainstem nuclei of spontaneously hypertensive rats [proceedings].
Topics: Animals; Brain Stem; Clonidine; Dopamine beta-Hydroxylase; Hydralazine; Hypertension; Methyldopa; Ph | 1979 |
Essential hypertension.
Topics: Clonidine; Humans; Hypertension | 1979 |
Clonidine withdrawal.
Topics: Clonidine; Humans; Hypertension; Substance Withdrawal Syndrome | 1979 |
Clonidine withdrawal mechanism and frequency of rebound hypertension. A reply to the letters of Dr. McMahon (1979) and Drs Whitsett & Chrysant (1979)
Topics: Clonidine; Humans; Hypertension; Substance Withdrawal Syndrome | 1979 |
Clonidine in hypertension: a 6-year review.
Topics: Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1979 |
Comparison of labetalol, clonidine and diazoxide intravenously administered in severe hypertension.
Topics: Adult; Clonidine; Diazoxide; Ethanolamines; Female; Humans; Hypertension; Injections, Intravenous; L | 1979 |
[Clofelin and depressin treatment of hypertension].
Topics: Adult; Antihypertensive Agents; Clonidine; Drug Evaluation; Drug Therapy, Combination; Female; Hexam | 1979 |
Effects of acute hypotension and hypertension on serum TSH concentrations in male rats.
Topics: Acute Disease; Angiotensin II; Animals; Clonidine; Dihydralazine; Hypertension; Hypotension; Male; N | 1979 |
Effects of long-term administration and withdrawal of clonidine on activity of sympathetic efferent nerve unit in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Hypertension; Kidney; Male; Neurons, Efferent; Rats; Sympathetic | 1979 |
Roberts's syndrome and clonidine.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Cleft Lip; Cleft Palate; Clonidine; Diazepam; | 1979 |
Antihypertensive effects of clonidine in tetraplegic subjects devoid of central sympathetic control.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Male; M | 1979 |
[Effects of high doses of clonidine and chlorthalidone].
Topics: Chlorthalidone; Clonidine; Drug Synergism; Female; Humans; Hypertension; Hypotension; Middle Aged | 1979 |
[Treatment of arterial hypertension with bumetanide and clonidine].
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Bumetanide; Clonidine; Diuretics; Drug Therapy, C | 1979 |
Effect of diphenylhydantoin on blood pressure of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Hypertension; Hypothalamus; Norepinephrine; Phenytoin; Rats | 1979 |
[Comparison of the antihypertensive action of normal clonidine and delayed-preparation clonidine].
Topics: Adult; Clonidine; Delayed-Action Preparations; Female; Hemodynamics; Humans; Hypertension; Male; Mid | 1979 |
[Treatment of stage III and severe hypertension with clonidine hydrochloride injection (author's transl)].
Topics: Adult; Aged; Clonidine; Female; Humans; Hypertension; Injections, Intravenous; Male; Middle Aged | 1979 |
Studies on the rebound hypertension after clonidine withdrawal in conscious hypertensive cats, rats, and dogs [proceedings].
Topics: Animals; Blood Pressure; Cats; Clonidine; Dogs; Humans; Hypertension; Rats; Substance Withdrawal Syn | 1977 |
[Effect of chronic oral administration of clonidine on the endogenous catecholamine metabolism in spontaneously hypertensive rats (author's transl)].
Topics: Administration, Oral; Adrenal Glands; Animals; Blood Pressure; Body Weight; Brain Stem; Catecholamin | 1977 |
Effect of clonidine on atrioventricular conduction.
Topics: Adult; Aged; Atrioventricular Node; Clonidine; Digoxin; Electrocardiography; Female; Heart Block; He | 1977 |
Clonidine withdrawal and hypertension.
Topics: Clonidine; Humans; Hypertension; Substance Withdrawal Syndrome | 1977 |
Pharmacokinetic and concentration-effect relationships of clonidine in essential hypertension.
Topics: Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Hypertensio | 1977 |
[Changes in central and regional hemodynamics during treatment of hypertension with hemiton].
Topics: Adult; Cerebrovascular Circulation; Clonidine; Hemodynamics; Humans; Hypertension; Middle Aged | 1977 |
[Clinical evaluation of a new hypotensive drug combination].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Benzyl Compounds; Child; Chlorothiazide; Clonidine | 1977 |
Combined clonidine and hydralazine therapy in severe and refractory hypertension.
Topics: Adult; Blood Pressure; Chronic Disease; Clonidine; Drug Evaluation; Drug Therapy, Combination; Femal | 1977 |
[Therapy of hypertensive crisis].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine | 1977 |
Clinical trial with intravenous clonidine in treatment of severe hypertension.
Topics: Adolescent; Adult; Aged; Child; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1977 |
[Long-term therapy of arterial hypertension. Preliminary report].
Topics: Adult; Aged; Antihypertensive Agents; Clonidine; Diet, Sodium-Restricted; Diuretics; Drug Therapy, C | 1977 |
[Hypotensive action of clonidine and baroreceptor reflexes in essential hypertension].
Topics: Carotid Sinus; Clonidine; Humans; Hypertension; Physical Exertion; Pressoreceptors; Reflex | 1977 |
Autonomic epilepsy: clonidine blockade of paroxysmal catecholamine release and flushing.
Topics: Autonomic Nervous System; Carbamazepine; Catecholamines; Climacteric; Clonidine; Epilepsy; Epilepsy, | 1978 |
Clonidine withdrawal.
Topics: Cardiac Surgical Procedures; Clonidine; Female; Humans; Hypertension; Hypotension; Middle Aged; Subs | 1978 |
[The therapy of the hypertensive form of late gestosis (author's transl)].
Topics: Adult; Cardiac Output; Clonidine; Female; Humans; Hypertension; Placenta; Pre-Eclampsia; Pregnancy; | 1978 |
Evaluation of intravenous clonidine in hypertensive emergencies.
Topics: Adult; Aged; Clonidine; Dose-Response Relationship, Drug; Emergencies; Female; Humans; Hypertension; | 1978 |
[Treatment of hypertensive emergencies].
Topics: Clonidine; Diazoxide; Emergencies; Family Practice; Furosemide; Hospitalization; Humans; Hypertensio | 1978 |
3-Methoxy-4-hydroxyphenylglycol in cerebrospinal fluid and vanillylmandelic acid in urine of humans with hypertension.
Topics: Blood Pressure; Clonidine; Female; Glycols; Humans; Hypertension; Male; Methoxyhydroxyphenylglycol; | 1978 |
The effects of antihypertensive medication on the control of the cardiovascular system during halothane anaesthesia in rats.
Topics: Anesthesia, Inhalation; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Drug Evaluation | 1978 |
Long-term treatment of refractory hypertensive patients with minoxidil.
Topics: Adult; Blood Pressure; Clonidine; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Fem | 1978 |
Refractory hypertension. Treatment with clonidine hydrochloride.
Topics: Adult; Blood Pressure; Body Weight; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Reni | 1978 |
Hypertension after clonidine withdrawal.
Topics: Adult; Aged; Clonidine; Female; Humans; Hypertension; Male; Substance Withdrawal Syndrome | 1978 |
Adverse effects of sympatholytic agents in patients with hypertension and sinus node dysfunction.
Topics: Aged; Arrhythmia, Sinus; Bradycardia; Clonidine; Electrocardiography; Female; Guanethidine; Heart Ra | 1978 |
Oral clonidine loading for rapid control of hypertension.
Topics: Administration, Oral; Adult; Aged; Clonidine; Drug Administration Schedule; Female; Humans; Hyperten | 1978 |
Atrioventricular dissociation in a patient receiving clonidine.
Topics: Adult; Clonidine; Female; Heart Block; Humans; Hypertension | 1978 |
[Treatment of arterial hypertension using clofelin].
Topics: Adult; Aged; Clonidine; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged | 1978 |
[Use of clopheline in the treatment of arterial hypertension and for arresting hypertensive crises].
Topics: Adult; Antihypertensive Agents; Clonidine; Hemodynamics; Humans; Hypertension; Middle Aged | 1978 |
Pharmacokinetics of clonidine and its relation to the hypotensive effect in patients.
Topics: Adult; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hypertension; Kinetics; Male; Middle A | 1978 |
The hypertensive psychiatric patient: pharmacologic problems.
Topics: Antihypertensive Agents; Clonidine; Depression; Diuretics; Drug Interactions; Guanethidine; Humans; | 1978 |
[Use of clonidine hydrochloride in the control of early postoperative hypertension in patients operated on for aortic coarctation in childhood. Considerations on 2 treated cases].
Topics: Age Factors; Aortic Coarctation; Child; Clonidine; Drug Evaluation; Humans; Hypertension; Male; Post | 1978 |
Role of renin and aldosterone suppression in the antihypertensive mechanism of clonidine.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Female | 1978 |
Effect of hypothalamic stimulation in spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Electric Stimulation; Hydralazine; Hypertension; Hyp | 1978 |
Clonidine as an antihypertensive drug in diabetics.
Topics: Clonidine; Diabetes Complications; Humans; Hypertension | 1978 |
Workup and treatment of the average hypertensive patient.
Topics: Benzothiadiazines; Clonidine; Diuretics; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa | 1978 |
[Combined clonidine-chlorthalidone therapy of hypertension].
Topics: Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension | 1978 |
Clonidine withdrawal. Mechanism and frequency of rebound hypertension.
Topics: Adult; Aged; Blood Pressure; Clonidine; Diet; Female; Heart Rate; Humans; Hypertension; Male; Middle | 1979 |
Acute effects of clonidine on blood pressure in normal individuals and patients with hypertension.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; | 1975 |
Apparent resistance to hypotensive effect of clonidine.
Topics: Adult; Blood Pressure; Clonidine; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged; | 1977 |
Monoamine metabolites in cerebrospinal fluid during treatment with clonidine or alprenolol.
Topics: Adult; Alprenolol; Biogenic Amines; Blood Pressure; Clonidine; Dopamine; Female; Humans; Hypertensio | 1977 |
Drugs for hypertension.
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Depression; Diuretics; Drug Combinations; Dru | 1977 |
[Effects of clonidine on various blood-coagulation parameters in hypertension].
Topics: Blood Coagulation; Blood Viscosity; Clonidine; Fibrinolysis; Humans; Hypertension; Platelet Aggregat | 1977 |
[Evaluation of hypotensive effects of clonidine].
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Ag | 1977 |
Efficacy and acceptability of different dosage schedules of clonidine.
Topics: Adult; Aged; Clonidine; Drug Administration Schedule; Female; Humans; Hypertension; Male; Middle Age | 1977 |
[Therapy of hypertensive crises].
Topics: Acute Disease; Adrenal Gland Neoplasms; Antihypertensive Agents; Clonidine; Diazoxide; Dihydralazine | 1977 |
Treatment of chronic essential hypertension.
Topics: Chlorothiazide; Clonidine; Diabetes Mellitus; Diet, Sodium-Restricted; Gout; Guanethidine; Humans; H | 1977 |
Prevention of some complications of essential hypertension.
Topics: Anesthesia; Antihypertensive Agents; Arteriosclerosis; Clonidine; Diabetes Complications; Drug Incom | 1977 |
Central nervous system actions of clonidine in hypertension.
Topics: Central Nervous System; Clonidine; Humans; Hyperkinesis; Hypertension; Sympathomimetics | 1977 |
[Clonidine seponation syndrome].
Topics: Clonidine; Humans; Hypertension; Injections, Intramuscular; Injections, Intravenous; Injections, Sub | 1977 |
Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs.
Topics: Acebutolol; Aldosterone; Animals; Chronic Disease; Clonidine; Corticosterone; Diet, Sodium-Restricte | 1977 |
Behavioral suppressant effects of clonidine in strains of normotensive and hypertensive rats.
Topics: Animals; Behavior, Animal; Clonidine; Conditioning, Operant; Depression, Chemical; Hypertension; Mal | 1977 |
Clonidine rebound hypertension.
Topics: Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Substance Withdrawal Syndrome | 1977 |
Studies covering combined treatments with xipamide. Results of a long-term antihypertensive treatment.
Topics: Adult; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Chlorides; Clonidine; Diuretics; Drug The | 1977 |
Central nervous system and hypertension.
Topics: Animals; Blood Pressure; Brain; Clonidine; Humans; Hypertension; Medulla Oblongata; Pressoreceptors; | 1977 |
Effect of certain antiadrenergic agents on systolic time intervals in essential hypertension.
Topics: Adult; Clonidine; Electrocardiography; Heart Rate; Humans; Hypertension; Male; Methyldopa; Middle Ag | 1977 |
[Pharmacotherapy of arterial hypertension].
Topics: Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hypertension; Methyldopa; Minoxidil; Nitropru | 1977 |
Antihypertensive and haemodynamic effects of clonidine-hydrochlorothiazide combination.
Topics: Adolescent; Adult; Clonidine; Drug Combinations; Female; Hemodynamics; Humans; Hydrochlorothiazide; | 1977 |
Clonidine-induced facilitation of baroreceptor reflex.
Topics: Clonidine; Humans; Hypertension; Male; Middle Aged; Pressoreceptors | 1977 |
[Therapy of hypertension with dimapres. Studies on the effect of the anti-hypertensive drug dimapres in newly adjusted and pretreated hypertensive patients].
Topics: Adult; Benzothiadiazines; Clonidine; Diuretics; Drug Combinations; Drug Evaluation; Female; Humans; | 1977 |
[Use of clonidine, furosemide and propranolol in the treatment of different phases of hypertension (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Clonidine; Drug Evaluation; Drug Therapy, Combination; Female; Furos | 1977 |
[The effects of clonidine on the renin-angiotensin-aldosterone system in patients with hypertension].
Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Clonidine; Drug Evaluation; Female; Humans; Hype | 1977 |
Effect of prolonged administration of clonidine to spontaneously hypertensive rats on blood pressure, cerebral norpinephrine content and angiographic finding in the kidney.
Topics: Animals; Blood Pressure; Body Weight; Brain; Clonidine; Female; Hypertension; Kidney; Norepinephrine | 1976 |
Factors influencing the choice of antihypertensive agents.
Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications; | 1976 |
Letter: Danger in nitroprusside therapy.
Topics: Adult; Aged; Clonidine; Ferricyanides; Humans; Hypertension; Hypotension; Male; Nitroprusside | 1976 |
Letter: Withdrawal of clonidine.
Topics: Clonidine; Drug Administration Schedule; Hypertension; Recurrence | 1976 |
[Clinical effects of a clonidine-chlorthalidone combination in the treatment of arterial hypertension].
Topics: Adult; Chlorthalidone; Clonidine; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypert | 1976 |
[Haemiton in ambulatory treatment of essential hypertension].
Topics: Adult; Aged; Ambulatory Care; Clonidine; Drug Evaluation; Female; Humans; Hypertension; Male; Middle | 1976 |
Symptoms of clonidine withdrawal after 17 days.
Topics: Clonidine; Female; Humans; Hypertension; Hypertension, Malignant; Middle Aged; Substance Withdrawal | 1976 |
Treatment of phaeochromocytoma and of clonidine withdrawal hypertension with labetalol.
Topics: Administration, Oral; Adult; Clonidine; Drug Evaluation; Ethanolamines; Female; Humans; Hypertension | 1976 |
Symposium on hypertension: part III. Sodium and potassium, catecholamines, renin and adrenal steroids as causal factors. Hypertension and atherosclerosis. Clonidine treatment and the renin axis.
Topics: Adrenal Cortex Hormones; Arteriosclerosis; Catecholamines; Clonidine; Humans; Hypertension; Potassiu | 1976 |
Renin and aldosterone suppression in the antihypertensive action of clonidine.
Topics: Adult; Aldosterone; Clonidine; Diet, Sodium-Restricted; Female; Humans; Hypertension; Male; Middle A | 1976 |
Effects of long-term administration of clonidine on plasma renin activity.
Topics: Adult; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Renin; Time Facto | 1976 |
[Methyldopa, clonidine and guanethidine in the treatment of hypertension].
Topics: Clonidine; Guanethidine; Humans; Hypertension; Methyldopa; Sympathetic Nervous System | 1976 |
[Use of hemiton and temechin in hypertensive disease].
Topics: Adult; Aged; Antihypertensive Agents; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1976 |
[Therapeutic combinations, side effects and interactions of antihypertensive drugs].
Topics: Antihypertensive Agents; Benzothiadiazines; Clonidine; Dihydralazine; Diuretics; Drug Interactions; | 1976 |
[Treatment of hypertensive crises].
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Humans; Hydralazine; Hypertension; Methyldopa; Nitrop | 1976 |
The over-shoot phenomenon on withdrawal of clonidine therapy.
Topics: Blood Pressure Determination; Clonidine; Electrocardiography; Female; Humans; Hypertension; Male; Mo | 1976 |
Clinical trail with clonidine hydrochloride.
Topics: Adult; Aged; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Mal | 1976 |
Clonidine in hypertension.
Topics: Clonidine; Humans; Hypertension | 1976 |
Clonidine in the treatment of hypertension.
Topics: Adult; Aged; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1976 |
[Better therapeutic response and decrease of the collateral negative effects of 2 hypotensive drugs (alpha-methyldopa and clonidine) obtained by means of their association].
Topics: Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Methyldopa; Middle A | 1976 |
[Changes in kidney function during hypotensive treatment].
Topics: Adult; Aged; Clonidine; Dihydralazine; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazid | 1976 |
Letter: Clonidine (Catapres) overshoot.
Topics: Adult; Aged; Clonidine; Female; Humans; Hypertension; Male; Substance Withdrawal Syndrome | 1975 |
Centrally acting alpha-adrenoceptor agonists in hypertension: mechanisms and their role in therapy.
Topics: Animals; Brain; Clonidine; Humans; Hypertension; Male; Methyldopa; Neurons; Substance Withdrawal Syn | 1976 |
Centrally acting alpha-agonists. Mechanisms and their role in the therapy of essential hypertension.
Topics: Animals; Blood Pressure; Brain Chemistry; Clonidine; Humans; Hypertension; Norepinephrine; Rats; Ref | 1976 |
Haemodynamic and endocrine changes during anti-hypertensive treatment with clonidine and its derivative St 600.
Topics: Cardiac Output; Clonidine; Heart Rate; Humans; Hypertension; Vascular Resistance | 1976 |
Plasma catecholamines and arterial hypertension.
Topics: Catecholamines; Clonidine; Humans; Hypertension; Propranolol; Renin; Sympathetic Nervous System | 1976 |
The central hypotensive action of clonidine and BAY 1470 in cats and rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Cats; Clonidine; Heart Rate; Hypertension; | 1975 |
Relationships between plasma renin activity and urinary and plasma catecholamines.
Topics: Blood Pressure; Clonidine; Dihydralazine; Furosemide; Humans; Hypertension; Hypertension, Renal; Nor | 1975 |
V World Congress of Cardiology Souvenir Oration. Recent trends in the management of hypertension.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hypertension; Male; Piperazines; Quin | 1975 |
Clonidine in Parkinson disease.
Topics: Aged; Antiparkinson Agents; Clonidine; Female; Humans; Hypertension; Levodopa; Male; Middle Aged; Pa | 1975 |
Letter: Dementia associated with clonidine therapy.
Topics: Aged; Clonidine; Dementia; Humans; Hypertension; Male; Methyldopa | 1975 |
Clonidine--a new antihypertensive.
Topics: Adolescent; Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; M | 1975 |
Clonidine (Catapres) for hypertension.
Topics: Clonidine; Drug Interactions; Drug Tolerance; Humans; Hypertension; Substance Withdrawal Syndrome | 1975 |
Plasma renin activity, blood pressure and sodium excretion during treatment with clonidine.
Topics: Administration, Oral; Adult; Blood Pressure; Clonidine; Creatinine; Depression, Chemical; Dose-Respo | 1975 |
Antihypertensive activity of erythro-1-(1-[2-(1,4-benzodioxan-2-yl)-2-OH-ET]-4-piperidyl)-2-benzimidazolinone (R 28935).
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Cardiac Output; Clonidine; Dogs; F | 1975 |
Proceedings: Effect of prolonged administration of clonidine to spontaneously hypertensive rats on blood pressure, cerebral norepinephrine content and angiographic finding in the kidney.
Topics: Animals; Blood Pressure; Brain; Clonidine; Disease Models, Animal; Female; Hypertension; Kidney; Nor | 1975 |
"Catapres in the management of hypertension".
Topics: Adult; Aged; Clonidine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Tolerance; Female; H | 1975 |
Combined clonidine-chlorthalidone therapy in hypertension. Two years' experience in 30 patients.
Topics: Adult; Aged; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Mal | 1975 |
Evaluation of clonidine hydrochloride (Catapres). A new antihypertensive agent.
Topics: Administration, Oral; Blood Pressure; Cardiac Output; Clonidine; Diuretics; Drug Evaluation; Drug Sy | 1975 |
The hypertensive patient. An algorithm for treatment.
Topics: Administration, Oral; Blood Pressure; Blood Urea Nitrogen; Clonidine; Creatinine; Diazoxide; Diureti | 1975 |
Clonidine overdose.
Topics: Adolescent; Clonidine; Diazoxide; Diuresis; Female; Furosemide; Heart Rate; Humans; Hypertension | 1975 |
Combipres for hypertension.
Topics: Chlorthalidone; Clonidine; Drug Combinations; Humans; Hypertension | 1975 |
Comparison between the effects of ST 600 and clonidine.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Cardiac Output; Clo | 1975 |
Letter: Clonidine overdose.
Topics: Clonidine; Diuresis; Humans; Hypertension | 1975 |
Hypotensive effect of clonidine during sodium depletion in the rat.
Topics: Animals; Blood Pressure; Clonidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug S | 1975 |
Clonidine hydrochloride (catapres) in the management of hypertension.
Topics: Adult; Aged; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1975 |
Changes in the arterial blood pressure responses of hypertensive rats to some drugs acting on the central sympathetic mechanisms.
Topics: Adrenal Glands; Animals; Blood Pressure; Clonidine; Disease Models, Animal; Hypertension; Male; Phys | 1975 |
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action on blood pressure and heart rate.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cats; Clonidine; Dogs; Dose-Response R | 1975 |
Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis.
Topics: Animals; Antihypertensive Agents; Aorta; Autonomic Nervous System; Blood Pressure; Cerebrovascular C | 1975 |
Pseudo-obstruction due to clonidine.
Topics: Adult; Clonidine; Humans; Hypertension; Intestinal Obstruction; Male | 1976 |
Applied pharmacology of anti-hypertensive drugs.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Guanethidine; Humans; Hydralazine; Hyperte | 1976 |
Letter: Aspects of clonidine therapy.
Topics: Blood Pressure; Clonidine; Glaucoma; Humans; Hypertension; Optic Nerve | 1976 |
[The effect of clonidine on renin-release (author's transl)].
Topics: Adult; Clonidine; Diuresis; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Male; | 1976 |
Letter: Late toxicity of clonidine withdrawal.
Topics: Clonidine; Female; Humans; Hypertension; Hypertension, Malignant; Middle Aged; Substance Withdrawal | 1976 |
Letter: Emergency treatment of hypertensive crisis following clonidine withdrawal.
Topics: Clonidine; Humans; Hypertension; Labetalol; Pheochromocytoma; Substance Withdrawal Syndrome | 1976 |
[Microcirculatory changes in patients with hypertensive disease caused by excessively lowered blood pressure after clofelin administration].
Topics: Adult; Blood Pressure; Clonidine; Erythrocytes; Female; Humans; Hypertension; Male; Microcirculation | 1992 |
Is imidazoline site a unique receptor? A correlation with clonidine-displacing substance activity.
Topics: Animals; Binding Sites; Brain; Brain Chemistry; Clonidine; Female; Humans; Hypertension; Imidazoles; | 1992 |
Central alpha 2-adrenoceptor-mediated pressor response to clonidine in conscious, spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Furosemide; Heart | 1992 |
[The diagnosis of uncorrectable refractory hypertension in patients with hypertension].
Topics: Adenylyl Cyclases; Adult; Clonidine; Dinoprostone; Drug Therapy, Combination; Humans; Hypertension; | 1992 |
Participation of arginine vasopressin-mediated and adrenergic system-mediated mechanisms in the hypertension induced by intracerebroventricular administration of NMDA in freely moving rats.
Topics: 2-Amino-5-phosphonovalerate; Animals; Arginine Vasopressin; Blood Pressure; Cerebral Ventricles; Clo | 1992 |
Effect of aspirin on the contractility of aortic smooth muscle in female spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Aorta; Aspirin; Blood Pressure; Clonidine; Female; Hypertension; | 1992 |
Effects of enalapril and clonidine on glomerular structure, function, and atrial natriuretic peptide receptors in SHHF/Mcc-cp rats.
Topics: Animals; Atrial Natriuretic Factor; Binding Sites; Clonidine; Cyclic GMP; Enalapril; Hypertension; H | 1992 |
Hyperreninemia and secondary hyperaldosteronism in a patient with pheochromocytoma and von Hippel-Lindau disease.
Topics: Adrenal Gland Neoplasms; Adult; Captopril; Catecholamines; Clonidine; Female; Humans; Hyperaldostero | 1992 |
Hypotensive drugs and the cellular energetic potential.
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension; Nifedipine; Phosphates; Propranolol; Water | 1992 |
[The cyclicity of changes in the autonomic regulation of the hemodynamics and the effects of clofelin in women with hypertension].
Topics: Adult; Autonomic Nervous System; Clonidine; Drug Evaluation; Female; Hemodynamics; Humans; Hypertens | 1992 |
Effects of clonidine-induced hypotension and dopamine-induced hypertension on blood flows in prostatic adenocarcinoma (Dunning R3327) and normal tissues.
Topics: Adenocarcinoma; Animals; Blood Pressure; Clonidine; Dopamine; Hypertension; Hypotension; Male; Prost | 1992 |
Pharmacokinetic comparison of a slow-release clonidine with a conventional formulation after acute and chronic administration in hypertensives.
Topics: Aged; Clonidine; Delayed-Action Preparations; Humans; Hypertension; Middle Aged; Norepinephrine | 1992 |
Effect of clonidine on blood pressure and GABAergic mechanisms in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Heart R | 1991 |
[Neuropeptide Y, orthosympathetic nervous system, hypertension and alpha-2 adrenergic receptors].
Topics: Animals; Clinical Protocols; Clonidine; Dogs; Hypertension; Neuropeptide Y; Norepinephrine; Proprano | 1991 |
Decreased density and sensitivity of alpha 2-adrenoceptors in the brain of spontaneously hypertensive rats.
Topics: Animals; Brain; Clonidine; Hypertension; Male; Mydriasis; Pupil; Radioligand Assay; Rats; Rats, Inbr | 1991 |
[Dysfunction of the central nervous alpha-adrenergic receptors in patients with essential hypertension].
Topics: Blood Pressure; Central Nervous System; Clonidine; Female; Growth Hormone; Humans; Hypertension; Mal | 1991 |
Somatostatin inhibits the centrally mediated hypertensive response to clonidine in freely moving rats.
Topics: Animals; Behavior, Animal; Blood Pressure; Brain; Clonidine; Hypertension; Injections, Intraventricu | 1991 |
First-choice antihypertensive drug use in the Glasgow Blood Pressure Clinic.
Topics: Adrenergic beta-Antagonists; Ambulatory Care Facilities; Angiotensin-Converting Enzyme Inhibitors; A | 1990 |
Modification of circadian blood pressure and heart rate variability by five different antihypertensive agents in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Heart Rate | 1991 |
Withdrawal symptoms in a postoperative patient.
Topics: Aged; Aorta, Abdominal; Aortic Aneurysm; Clonidine; Humans; Hypertension; Intubation, Gastrointestin | 1992 |
Effect of chronic treatment with clonidine and spironolactone on cold-induced elevation of blood pressure.
Topics: Aldosterone; Angiotensin II; Animals; Blood Pressure; Body Weight; Clonidine; Cold Temperature; Drin | 1991 |
[The characteristics of treating hypertension with clofelin in pregnant women].
Topics: Adult; Clonidine; Discriminant Analysis; Drug Evaluation; Female; Hemodynamics; Humans; Hypertension | 1991 |
Regional hemodynamic effects of rilmenidine and clonidine in the conscious spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart | 1991 |
Pheochromocytoma: new concepts and future trends.
Topics: Acidosis, Lactic; Adrenal Gland Neoplasms; Adult; Animals; Antihypertensive Agents; Antineoplastic C | 1991 |
[Side effects of long-term drug therapy of patients with uncomplicated arterial hypertension in a polyclinic].
Topics: Adolescent; Adult; Antihypertensive Agents; Cardiovascular Diseases; Clonidine; Dose-Response Relati | 1991 |
[The use of total intravenous anesthesia utilizing klofelin in hypertension patients].
Topics: Adult; Aged; Anesthesia, Intravenous; Clonidine; Female; Hemodynamics; Humans; Hypertension; Male; M | 1991 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlo | 1991 |
Contractile reactivity of isolated resistance arteries after 4 weeks of treatment with rilmenidine, clonidine or hydralazine in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Clonidine; Hydralazine; Hypertension; In | 1991 |
Superior mesenteric artery vascular resistance is higher in hypertensives and is lowered by clonidine.
Topics: Adult; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Mesenteric Arterie | 1991 |
Synthesis and antihypertensive activity of some 2-aminobenzimidazole and indole derivatives.
Topics: Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Clonidine; Hypertension; Indoles; | 1991 |
Improving compliance in an inner-city hypertensive patient population.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Aged, 80 and over; Black or African Am | 1991 |
[Brain adrenoreceptors in rats with inherited arterial hypertension due to emotional stress].
Topics: Animals; Brain; Clonidine; Dihydroalprenolol; Hypertension; Prazosin; Radioligand Assay; Rats; Rats, | 1991 |
Interactions of clonidine and nifedipine in moderately severe hypertensive patients.
Topics: Blood Pressure; Clonidine; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination | 1991 |
Intrahypothalamic clonidine infusion prevents NaCl-sensitive hypertension.
Topics: Analysis of Variance; Animals; Blood Pressure; Body Weight; Clonidine; Heart Rate; Heart Ventricles; | 1991 |
Utility of a transdermal delivery system for antihypertensive therapy. Part 2.
Topics: Administration, Cutaneous; Antihypertensive Agents; Clonidine; Cost-Benefit Analysis; Drug Prescript | 1991 |
Utility of a transdermal delivery system for antihypertensive therapy. Part 1.
Topics: Administration, Cutaneous; Clinical Protocols; Clonidine; Cost-Benefit Analysis; Drug Prescriptions; | 1991 |
Administration of carbamazepine in the nucleus of the solitary tract inhibits the antihypertensive effect of clonidine.
Topics: Animals; Blood Pressure; Carbamazepine; Clonidine; Hypertension; Medulla Oblongata; Rats; Rats, Inbr | 1991 |
Evidence for clonidine presynaptically modulating amino acid release in the rostral ventral medulla: role in hypertension.
Topics: Amino Acids; Animals; Aspartic Acid; Clonidine; Female; gamma-Aminobutyric Acid; Glutamates; Glutami | 1990 |
Pressure responses of hypertensive patients treated with thiazides, beta blockers and clonidine during a psychological experimental stress situation.
Topics: Adrenergic beta-Antagonists; Adult; Benzothiadiazines; Blood Pressure; Clonidine; Diuretics; Female; | 1990 |
Myocardial infarction accompanying acute clonidine withdrawal in a patient without a history of ischemic coronary artery disease.
Topics: Aged; Clonidine; Electrocardiography; Female; Humans; Hypertension; Myocardial Infarction; Substance | 1991 |
Evaluation of drug therapy for treatment of hypertensive urgencies in the emergency department.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy; Emergency Service, Hospital; Evalu | 1991 |
Left ventricular muscle mass and diastolic function in patients with essential hypertension under long-term clonidine monotherapy.
Topics: Blood Flow Velocity; Blood Pressure; Cardiac Output; Clonidine; Diastole; Echocardiography; Echocard | 1991 |
Glucagon and clonidine testing in the diagnosis of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Catechols; Clonidine; Drug Therapy, Combination; Glucagon; Humans; Hyperten | 1991 |
Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats via sympatholytic and renal effects.
Topics: Animals; Blood Pressure; Calcium, Dietary; Clonidine; Diuresis; Hypertension; Hypothalamus, Anterior | 1991 |
Clonidine suppression test reliably differentiates phaeochromocytoma from essential hypertension.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Clonidine; Diagnosis, Differential; Epinephrine; F | 1991 |
[Pheochromocytoma diagnosed during quinapril therapy].
Topics: Adrenal Gland Neoplasms; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clonidin | 1990 |
[Correlations between catecholamines and prostaglandins in patients with primary arterial hypertension and pheochromocytoma in basic conditions and after administration of clonidine].
Topics: Adrenal Gland Neoplasms; Adult; Clonidine; Dinoprost; Dinoprostone; Epinephrine; Humans; Hypertensio | 1990 |
The importance of plasma 3,4-dihydroxyphenylglycol (DOPEG) in analyses of the sympathetic nervous system in vivo.
Topics: Adolescent; Adult; Aged; Animals; Clonidine; Desipramine; Female; Humans; Hypertension; Male; Methox | 1990 |
Effect of clonidine on serum inorganic phosphorus in patients with essential arterial hypertension.
Topics: Blood Pressure; Clonidine; Female; Growth Hormone; Humans; Hypertension; Insulin; Male; Middle Aged; | 1990 |
[The effect of clonidine on humoral factors in patients with arterial hypertension].
Topics: Adrenal Gland Neoplasms; Aldosterone; Atrial Natriuretic Factor; Catecholamines; Clonidine; Diagnosi | 1990 |
Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Volume; Cardiomegaly; Clonidine; Drug Therap | 1990 |
Investigation of the mechanism(s) of 8-OH-DPAT-mediated inhibition of plasma insulin in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Blood Glucose; Blood Pressure; Clonidin | 1990 |
Clonidine abolishes exaggerated pressor responses to shaker stress in spontaneously hypertensive rats.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenalectomy; Animals; Blood Pressure; Central Nervous Sys | 1990 |
Alterations in brainstem alpha 2 adrenoreceptor activity in pyridoxine-deficient rat model of hypertension.
Topics: Animals; Brain Stem; Clonidine; Hypertension; Male; Norepinephrine; Rats; Rats, Inbred Strains; Rece | 1990 |
[Plasma levels of beta-endorphin and ACTH and serum levels of cortisol in different stages of arterial hypertension before and after clonidine therapy].
Topics: Adrenocorticotropic Hormone; Adult; Aged; beta-Endorphin; Blood Pressure; Chronic Disease; Clonidine | 1990 |
Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats by a sympatholytic mechanism.
Topics: Animals; Blood Pressure; Calcium, Dietary; Clonidine; Hypertension; Hypothalamus; Male; Norepinephri | 1990 |
Central alpha-2 adrenergic function in patients with essential hypertension. Comparative study of growth hormone (GH) secretion stimulated by clonidine and GH-releasing hormone.
Topics: Adult; Blood Glucose; Blood Pressure; Clonidine; Female; Growth Hormone; Growth Hormone-Releasing Ho | 1990 |
[Clonidine abstinence syndrome. A clinical case].
Topics: Clonidine; Humans; Hypertension; Male; Middle Aged; Substance Withdrawal Syndrome; Tachycardia, Supr | 1990 |
[Hypokalemia caused by nifedipine].
Topics: Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Hypokalemia; Nifedipine | 1990 |
Altered plasma leucine-enkephalin concentrations in patients with established hypertension.
Topics: Adult; Blood Pressure; Clonidine; Enkephalin, Leucine; Exercise; Feedback; Humans; Hypertension; Mal | 1990 |
The effects of enalapril on urinary protein excretion in patients with idiopathic membranous nephropathy.
Topics: Adult; Blood Pressure; Clonidine; Enalapril; Female; Glomerulonephritis, Membranous; Humans; Hyperte | 1990 |
Comparison of clinic and home blood pressure levels and the role of the sympathetic nervous system in clinic-home differences.
Topics: Administration, Oral; Adolescent; Adult; Ambulatory Care Facilities; Blood Pressure; Blood Pressure | 1990 |
[The local use of clofelin in the combined treatment of patients with periodontosis and hypertension].
Topics: Administration, Topical; Adult; Aggressive Periodontitis; Blood Pressure; Clonidine; Combined Modali | 1990 |
Haemodynamic resistance of forearm vessels during prolonged drug treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination | 1990 |
Vitamin B6 and hypertension.
Topics: Animals; Blood Pressure; Clonidine; Epinephrine; Hypertension; Male; Methyldopa; Norepinephrine; Rat | 1990 |
Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine.
Topics: Administration, Oral; Blood Pressure; Cerebrovascular Circulation; Clonidine; Emergencies; Female; H | 1990 |
Effects of alpha-2 agonists on renal function in hypertensive humans.
Topics: Adrenergic alpha-Agonists; Clonidine; Diuresis; Glomerular Filtration Rate; Guanabenz; Humans; Hyper | 1985 |
Alpha 2-adrenoceptor agonists in the treatment of hypertension.
Topics: Adrenergic alpha-Agonists; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hyper | 1985 |
Hemodynamic effects of clonidine in patients with acute myocardial infarction complicated by hypertension.
Topics: Adult; Aged; Clonidine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardial In | 1986 |
Treatment of hypertensive emergencies: classic and newer approaches.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Emergencies; Female; Heart Rate; Hu | 1986 |
The haemodynamic effects of clonidine in patients with grade III to IV hypertension.
Topics: Aged; Aged, 80 and over; Clonidine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; P | 1986 |
Clonidine and left ventricular function in ten patients with essential hypertension.
Topics: Adult; Aged; Blood Pressure; Clonidine; Electrocardiography; Female; Humans; Hypertension; Male; Mid | 1986 |
Progress in the treatment of essential hypertension.
Topics: Adrenergic Agents; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Converting | 1985 |
[Clinical and experimental study of clofelin pharmacodynamics].
Topics: Action Potentials; Animals; Antihypertensive Agents; Cardiovascular System; Clonidine; Drug Evaluati | 1986 |
Safety aspects of long-term antihypertensive therapy (10 years) with clonidine.
Topics: Adult; Blood Pressure; Cardiomegaly; Cholesterol; Clonidine; Drug Therapy, Combination; Electrocardi | 1987 |
Plasma beta-endorphins and catecholamines before and after clonidine in essential hypertension and pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; beta-Endorphin; Blood Pressure; Catecholamines; Clonidine; Dopamine; | 1987 |
Reflex vasoconstrictor responses to cardiopulmonary baroreceptor unloading, head-up tilt, and cold pressor testing in elderly mild-to-moderate hypertensives: effect of clonidine.
Topics: Aged; Clonidine; Cold Temperature; Forearm; Humans; Hypertension; Lower Body Negative Pressure; Male | 1987 |
Regional brain concentrations of several putative peptide neurotransmitters in normotensive and spontaneously hypertensive rats: effects of continuous (10-day) clonidine infusion.
Topics: Animals; Brain Chemistry; Clonidine; Female; Hypertension; Infusion Pumps; Infusions, Parenteral; Ne | 1987 |
Reversal of left ventricular hypertrophy after one-year treatment with clonidine: relationship between echocardiographic findings, blood pressure, and urinary catecholamines.
Topics: Adult; Blood Pressure; Cardiomegaly; Clonidine; Echocardiography; Epinephrine; Female; Follow-Up Stu | 1987 |
Normalization of blood pressure and plasma concentrations of beta-endorphin and leucine-enkephalin in patients with primary hypertension after treatment with clonidine.
Topics: Adult; beta-Endorphin; Blood Pressure; Clonidine; Enkephalin, Leucine; Humans; Hydrocortisone; Hyper | 1987 |
Evaluation of the antihypertensive effect of TTS clonidine by multiple 24-hour automatic blood pressure monitoring.
Topics: Administration, Cutaneous; Blood Pressure; Clonidine; Computers; Female; Heart Rate; Humans; Hyperte | 1987 |
Increased plasma norepinephrine and sympathetic nervous activity in essential hypertensive and uremic humans: effects of clonidine.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Clonidine; Female; Heart Rate; Humans; Hypertension; Ma | 1987 |
The effect of clonidine on pituitary hormone secretion in physiological and pathological states.
Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; Clonidine; Cushing Syndrome; Female; Growth Horm | 1987 |
Dietary Ca2+ supplementation prevents the exaggerated responsiveness of anterior hypothalamic alpha 2-adrenoceptors in NaCl-loaded spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Calcium, Dietary; Clonidine; Diet; Heart Rate; Hypertension; H | 1989 |
Decreased density of alpha 2-adrenoceptors in medulla oblongata of spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Clonidine; Hypertension; Medulla Oblongata; Norepinephrine; Phentolamine; Pr | 1989 |
Regression of cardiac hypertrophy: experimental and clinical results.
Topics: Animals; Cardiomegaly; Clonidine; Enalapril; Humans; Hypertension; Nifedipine; Prazosin; Rats; Rats, | 1987 |
Possible involvement of brain opioid peptides in clonidine-induced hypotension in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Endorphins; Heart Rate; Hypertension; Male; Naltrexone; R | 1989 |
Centrally mediated increased sympathetic activity is not important in the genesis of ACTH-induced hypertension in sheep.
Topics: Adrenocorticotropic Hormone; Animals; Blood Pressure; Clonidine; Female; Heart Rate; Hypertension; I | 1989 |
Differential effects of dopaminergic drugs on open-field behavior of spontaneously hypertensive rats and normotensive Wistar-Kyoto rats.
Topics: Amphetamine; Animals; Apomorphine; Benzazepines; Clonidine; Desipramine; Dopamine; Dopamine Agents; | 1989 |
Severe symptomless hypertension.
Topics: Blood Pressure; Clonidine; Humans; Hypertension | 1989 |
The SHR exhibits less "anxiety" but increased sensitivity to the anticonflict effect of clonidine compared to normotensive controls.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Clonidine; Conflict, Psychological; Drinking Behavior; Electr | 1989 |
Intravenous labetalol for the treatment of hypertension after carotid endarterectomy.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Calcium Channel Blockers; Clonidine; Endarterecto | 1989 |
[Effects of clonidine on tourniquet-induced systemic arterial hypertension in general anesthesia].
Topics: Adult; Clonidine; Humans; Hypertension; Tourniquets | 1989 |
Impairment of modulating role of testosterone in growth hormone response to clonidine in essential hypertension.
Topics: Adult; Blood Pressure; Clonidine; Growth Hormone; Humans; Hypertension; Male; Middle Aged; Osmolar C | 1989 |
Centrally acting alpha-2 agonists, peripherally acting adrenergic-blocking drugs, and direct vasodilators in the treatment of mild and moderate essential hypertension.
Topics: Adult; Aged; Black People; Clinical Protocols; Clonidine; Drug Therapy, Combination; Humans; Hydrala | 1989 |
New indices in the evaluation of clonidine transdermal therapy of hypertension.
Topics: Administration, Cutaneous; Arteries; Blood Pressure Determination; Clonidine; Female; Humans; Hypert | 1989 |
An enhanced diuresis and natriuresis in response to clonidine in spontaneously hypertensive rats.
Topics: Animals; Clonidine; Diuresis; Hypertension; Natriuresis; Rats; Rats, Inbred SHR; Stimulation, Chemic | 1989 |
Altered plasma leucine-enkephalin concentrations in patients with established hypertension may be involved in impaired regulation of blood pressure.
Topics: Adult; Blood Pressure; Clonidine; Enkephalin, Leucine; Exercise Test; Humans; Hypertension; Male; No | 1989 |
Osmoregulation of vasopressin during acute lowering of arterial pressure by clonidine in moderate hypertension.
Topics: Blood Pressure; Clonidine; Drug Evaluation; Female; Humans; Hypertension; Infusions, Intravenous; Ma | 1989 |
Effect of transdermal clonidine on the endocrine responses to insulin-induced hypoglycemia in essential hypertension.
Topics: Administration, Cutaneous; Adult; Aldosterone; Blood Glucose; Blood Pressure; Clonidine; Diabetes Co | 1989 |
The captopril glomerular filtration rate renogram in renovascular hypertension.
Topics: Adult; Aged; Angiotensin I; Blood Pressure; Captopril; Catecholamines; Clonidine; Diagnosis, Differe | 1989 |
Therapy of venous hypertension in calves with total artificial heart (TAH).
Topics: Animals; Antihypertensive Agents; Captopril; Cardiac Pacing, Artificial; Cattle; Central Venous Pres | 1989 |
Salt sensitivity in human essential hypertension: effect of renin-angiotensin and sympathetic nervous system blockade.
Topics: Adult; Aged; Blood Pressure; Captopril; Clonidine; Diet, Sodium-Restricted; Drug Resistance; Female; | 1989 |
Blood pressure and blood pressure variability following withdrawal of propranolol and clonidine.
Topics: Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Propranolol | 1989 |
Transdermal clonidine compared with hydrochlorothiazide as monotherapy in elderly hypertensive males.
Topics: Administration, Cutaneous; Aged; Blood Pressure; Clonidine; Heart Rate; Humans; Hydrochlorothiazide; | 1989 |
Pharmacokinetics and antihypertensive effects of low dose clonidine during chronic therapy.
Topics: Adult; Aged; Blood Pressure; Clonidine; Female; Half-Life; Heart Rate; Humans; Hypertension; Male; M | 1989 |
Phaeochromocytomas secreting adrenaline but not noradrenaline do not cause hypertension and require precise adrenaline measurement for diagnosis.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Chromatography, High Pressure Liquid; Clonidine; E | 1989 |
Plasma dilution during transdermal clonidine antihypertensive monotherapy.
Topics: Administration, Cutaneous; Antihypertensive Agents; Blood Proteins; Clonidine; Hemoglobins; Humans; | 1989 |
Acute reduction of blood pressure in asymptomatic patients with severe hypertension. An idea whose time has come--and gone.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Administration Schedule; Hu | 1989 |
Opiate receptors and the endorphin-mediated cardiovascular effects of clonidine in rats: evidence for hypertension-induced mu-subtype to delta-subtype changes.
Topics: Animals; Blood Pressure; Clonidine; Endorphins; Enkephalin, Leucine; Heart Rate; Hypertension; Male; | 1987 |
Raised levels of an endogenous nonadrenergic substance in the serum of pregnancy-induced hypertension patients.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Parity; Placenta; Pre-Eclampsia; Pregnancy; Pregnanc | 1987 |
Regulation of alpha 2-adrenoceptor density in normotensive and hypertensive man.
Topics: Adenylyl Cyclases; Blood Platelets; Clonidine; Furosemide; Humans; Hypertension; Male; Nifedipine; N | 1987 |
The neural basis of salt sensitivity in the rat: altered hypothalamic function.
Topics: Animals; Blood Pressure; Clonidine; Disease Models, Animal; Heart Rate; Hypertension; Hypothalamus, | 1988 |
Recurrent attacks of vomiting, hypertension and psychotic depression: a syndrome of periodic catecholamine and prostaglandin discharge.
Topics: Adolescent; Adrenocorticotropic Hormone; Arginine Vasopressin; Child, Preschool; Clonidine; Dinopros | 1988 |
Are opioid receptors involved in the bradycardiac and hypotensive action of clonidine?
Topics: Animals; Blood Pressure; Bradycardia; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hyper | 1988 |
Hypothalamic microinjection of alpha 2-adrenoceptor agonists causes greater sympathoinhibition in spontaneously hypertensive rats on high NaCl diets.
Topics: Animals; Anterior Hypothalamic Nucleus; Blood Pressure; Clonidine; Depression, Chemical; Heart Rate; | 1988 |
Differences in the ability of yohimbine to antagonize the hypotensive effect of clonidine in normotensive and spontaneously hypertensive anesthetized rats.
Topics: Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Hypertension; Rats; Rats, Inbr | 1988 |
[Optimization of hypotensive therapy in hospitals].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Cerebrovascular Circulation; Clonidine; Drug C | 1985 |
Long-term experience with the combination of clonidine and beta-adrenoceptor blocking agents in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Clonidine; Drug Evaluation; Drug Therapy, | 1985 |
Chronic salt loading and central adrenergic mechanisms in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Central Nervous System; Clonidine; Dopamine; Heart Rate; Hexamethonium; Hex | 1985 |
Differences in response of black hypertensives to alpha vs. beta adrenergic antagonists: preliminary findings.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Black People; Clonidine; Female; Heart Ra | 1985 |
[Therapy of the hypertensive crisis].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Calcium Channel Blockers; Clonidine; Dihydralazin | 1985 |
[What is safe in the therapy of hypertensive heart disease?].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Animal | 1985 |
Current concepts in treatment of hypertensive urgencies.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin-Co | 1986 |
Overview of alpha 2-adrenoceptor agonists with a central action.
Topics: Adrenergic alpha-Agonists; Blood Pressure; Central Nervous System; Clonidine; Guanfacine; Guanidines | 1986 |
[Treatment with Pharmachim's Chlophazolin of hypertension and symptomatic hypertonia].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Chronic Disease; | 1986 |
Is there a role for renal alpha 2-adrenoceptors in the pathogenesis of hypertension?
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Gluconeogenesis; Guanfacine; Guanidines; Hypertension | 1987 |
Advantages and disadvantages of alpha 2-adrenoceptor agonists for systemic hypertension.
Topics: Adrenergic beta-Agonists; Antihypertensive Agents; Clonidine; Hemodynamics; Humans; Hypertension; Su | 1988 |
Electrophysiologic and hemodynamic effects of chronic oral therapy with the alpha 2-agonists clonidine and tiamenidine in hypertensive volunteers.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Adult; Aged; Antihypertensive Agents; Clonidine; He | 1988 |
[Hemodynamic correlates of selective beta 1 adrenergic receptor blockade by cordanum during hemiton monotherapy in children with primary arterial hypertension].
Topics: Adolescent; Adrenergic beta-Antagonists; Antihypertensive Agents; Child; Clonidine; Hemodynamics; Hu | 1988 |
How urgent is 'urgent' hypertension?
Topics: Clonidine; Emergencies; Hospitalization; Humans; Hypertension; Nifedipine | 1989 |
Severe hypertension induced by naloxone.
Topics: beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Humans; Hypertension; Male; Middle Aged; Nalo | 1985 |
Pharmacological, hemodynamic and biochemical mechanisms involved in the blood pressure lowering effects of pergolide, in normotensive and hypertensive dogs.
Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Denervation; Dogs; Electric Stimulation; Ergolines; | 1985 |
[Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects].
Topics: Blood Pressure; Cardiac Volume; Cardiomegaly; Cardiomyopathy, Hypertrophic; Clonidine; Coronary Circ | 1985 |
Opioid-mediated cardiovascular effects of clonidine in spontaneously hypertensive rats: elimination by neonatal treatment with monosodium glutamate.
Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; beta-Endorphin; Blood Pressure; Clonidin | 1986 |
Endogenous opioid peptides: do they mediate the acute antihypertensive action of clonidine in humans?
Topics: Adult; Aged; Aldosterone; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Humans; Hypertensio | 1986 |
Clonidine normalizes low plasma beta-endorphin concentration and blood pressure in young men with mild essential hypertension.
Topics: Adult; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Humans; Hypertension; Male; Radioimmun | 1986 |
Effects of angiotensin and noradrenaline on atrial natriuretic peptide levels in man.
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Clonidi | 1987 |
[Preoperative oral clonidine improves the cardiovascular stability of hypertensive and coronary patients undergoing surgery].
Topics: Administration, Oral; Cardiovascular System; Clonidine; Coronary Disease; Humans; Hypertension; Prem | 1987 |
[Hemodynamic effect of a combination of prazosin with cardiac depressants in the treatment of hypertension].
Topics: Anti-Arrhythmia Agents; Celiprolol; Clonidine; Drug Evaluation; Drug Synergism; Drug Therapy, Combin | 1988 |
[Assay of 3-methoxy-4-hydroxyphenylethylene glycol in hypertensive outbreaks after cardiac surgery. Effect of clonidine].
Topics: Cardiac Surgical Procedures; Clonidine; Glycols; Humans; Hypertension; Methoxyhydroxyphenylglycol | 1988 |
Catapres-TTS: a two year posttrial followup.
Topics: Administration, Cutaneous; Clonidine; Drug Eruptions; Evaluation Studies as Topic; Follow-Up Studies | 1988 |
[Luciani-Wenckeback period and clonidine. Presentation of a case].
Topics: Aged; Clonidine; Electrocardiography; Female; Heart Block; Humans; Hypertension | 1988 |
Effects of clonidine, alpha-methyldopa and hydralazine on met-enkephalinergic neurons in cerebral nuclei of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Clonidine; Enkephalin, Methionine; Fluorescent Antibody Technique; H | 1985 |
[Drug resistance and withdrawal syndrome--study on receptors].
Topics: Animals; Clonidine; Deoxyepinephrine; Drug Resistance; Humans; Hypertension; Receptors, Opioid; Subs | 1985 |
Central alpha-activation by clonidine reduces plasma level of beta-endorphin in patients with essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Aged; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Fem | 1985 |
Central adrenergic receptor control of renal function in conscious hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Guanabenz; Hypertension; Kidney; Male; Natriuresis; Phenoxybenza | 1986 |
Changed sensitivity of alpha 2-adrenoceptors mediating a decrease in protein kinase inhibitor activity in the brain of vasopressin-hypertensive rats.
Topics: Animals; Blood Pressure; Brain; Carrier Proteins; Clonidine; Cyclic GMP; Hydroxydopamines; Hypertens | 1986 |
Role of drugs modifying sympathetic nervous system activity in the treatment of hypertension.
Topics: Binding Sites; Blood Circulation; Brain; Clonidine; Efferent Pathways; Ganglia, Sympathetic; Humans; | 1985 |
Naloxone does not affect the cardiovascular, sedative or neurohormonal effects of clonidine in normal and hypertensive man.
Topics: Adult; Blood Pressure; Clonidine; Double-Blind Method; Hemodynamics; Hormones; Humans; Hypertension; | 1985 |
Increased sympatho-adrenal tone and adrenal medulla reactivity in DOCA-salt hypertensive rats.
Topics: Adrenal Medulla; Animals; Carotid Arteries; Clonidine; Desoxycorticosterone; Epinephrine; Hypertensi | 1986 |
The effects of intracerebroventricular injection of clonidine on conditioned pressor and adrenergic responses in rats.
Topics: Animals; Clonidine; Conditioning, Operant; Epinephrine; Heart Rate; Hypertension; Injections, Intrav | 1986 |
Growth hormone responses to clonidine and GRF in spontaneously hypertensive rats: neuroendocrine evidence for an enhanced responsiveness of brain alpha 2-adrenoceptors in genetical hypertension.
Topics: Animals; Blood Pressure; Brain; Clonidine; Growth Hormone; Growth Hormone-Releasing Hormone; Hyperte | 1986 |
Rebound hypertension after discontinuation of transdermal clonidine therapy.
Topics: Administration, Cutaneous; Aged; Blood Pressure; Clonidine; Humans; Hypertension; Male; Norepinephri | 1987 |
Prazosin partly blocks clonidine-induced hypotension in patients with essential hypertension.
Topics: Adult; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination; Heart Rate; Humans; Hyp | 1987 |
On the relationship between clonidine hypotension and brain beta-endorphin in the spontaneously hypertensive rat: studies with alpha adrenergic and opiate blockers.
Topics: Animals; beta-Endorphin; Blood Pressure; Brain; Clonidine; Endorphins; Heart Rate; Hypertension; Hyp | 1987 |
Cardiovascular and neurohormonal changes following central sympathetic blockade with clonidine in human unilateral renal artery stenosis.
Topics: Adult; Aged; Aldosterone; Captopril; Clonidine; Hemodynamics; Humans; Hypertension; Middle Aged; Nor | 1988 |
Noradrenergic hyperactivity in primary hypertension; central and peripheral markers of both behavioral pathogenesis and efficacy of sympatholytic and relaxation therapy.
Topics: Adult; Aged; Blood Pressure; Clonidine; Combined Modality Therapy; Female; Humans; Hypertension; Mal | 1988 |
Increased non-collagen protein synthesis in the posterior cerebral artery in spontaneously hypertensive rats.
Topics: Animals; Cerebral Arteries; Clonidine; Hydroxydopamines; Hypertension; Male; Oxidopamine; Proline; P | 1986 |
Emotional hyperthermia in spontaneously hypertensive rats.
Topics: Animals; Body Temperature; Clonidine; Dose-Response Relationship, Drug; Emotions; Hypertension; Male | 1986 |
Behavioral and physiological detection of classically-conditioned blood pressure reduction.
Topics: Animals; Blood Pressure; Clonidine; Conditioning, Classical; Hypertension; Male; Rats; Rats, Inbred | 1988 |
Clonidine induced variations of plasma norepinephrine and blood pressure in essential hypertension.
Topics: Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Middle Aged; Norepinephrine; Sympatheti | 1987 |
Altered neuropeptide concentrations in spontaneously hypertensive rats: cause or consequence?
Topics: Animals; Arginine Vasopressin; beta-Endorphin; Brain; Clonidine; Endorphins; Enkephalin, Leucine; Hy | 1985 |
beta-Endorphin and essential hypertension: importance of the clonidine-naloxone interaction.
Topics: Adult; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Female; Hemodynamics; Humans; Hyperten | 1985 |
[Transdermal clonidine: a new therapeutic approach in essential hypertension?].
Topics: Administration, Topical; Adult; Aged; Blood Pressure; Clonidine; Drug Eruptions; Drug Therapy, Combi | 1985 |
Beta-endorphin: a common factor in the antihypertensive action of clonidine-type imidazolines in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; beta-Endorphin; Blood Pressure; Brimonidine Tartrate; Clonidine; D | 1985 |
Changes of plasma levels of beta-endorphin-like immunoreactivity after acute clonidine administration in patients with essential hypertension.
Topics: Adult; beta-Endorphin; Blood Pressure; Clonidine; Endorphins; Female; Heart Rate; Humans; Hypertensi | 1985 |
[Sublingual clonidine in a hypertensive crisis].
Topics: Administration, Sublingual; Clonidine; Humans; Hypertension | 1988 |
General pharmacology of the novel centrally acting antihypertensive agent moxonidine.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Cats; Chemical Phenomena; Ch | 1988 |
Transcription medication error with transdermal clonidine.
Topics: Administration, Cutaneous; Aged; Clonidine; Female; Humans; Hypertension; Medication Errors | 1988 |
Rebound hypertension after discontinuation of transdermal clonidine.
Topics: Administration, Cutaneous; Blood Pressure; Clonidine; Humans; Hydrochlorothiazide; Hypertension; Mal | 1988 |
[The relation of hypotensive effects of nifedipine and clonidine and changes in platelet-free calcium and serum-free calcium in essential hypertension].
Topics: Adult; Aged; Blood Platelets; Calcium; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; N | 1988 |
Reduced beta-endorphin secretion in young patients with mild essential hypertension at rest and during exercise.
Topics: Adult; Clonidine; Endorphins; Humans; Hypertension; Male; Physical Exertion | 1988 |
Biochemical evidence that brainstem adrenaline-containing neurons are activated during clonidine withdrawal in the spontaneously hypertensive rat.
Topics: Animals; Brain Stem; Clonidine; Epinephrine; Hypertension; Male; Neurons; Norepinephrine; Rats; Rats | 1988 |
Safe use of clonidine, nifedipine and vitamin K in hepatic porphyria.
Topics: Adult; Clonidine; Humans; Hypertension; Liver Diseases; Male; Nifedipine; Porphyrias; Vitamin K | 1988 |
[Hypertensive crisis after withdrawal of clonidine and nadolol. Case report and review of the literature].
Topics: Clonidine; Female; Humans; Hypertension; Kidney Failure, Chronic; Kidney Transplantation; Middle Age | 1987 |
Fructose-induced insulin resistance and hypertension in rats.
Topics: Animals; Blood Glucose; Clonidine; Fatty Acids, Nonesterified; Fructose; Hypertension; Insulin; Insu | 1987 |
Medical treatment of homeless hypertensives.
Topics: Administration, Cutaneous; Clonidine; Delayed-Action Preparations; Humans; Hypertension; Ill-Housed | 1988 |
[Diagnostic significance of the clonidine suppression test in suspected pheochromocytoma].
Topics: Adrenal Cortex Function Tests; Adrenal Gland Neoplasms; Adult; Clonidine; Epinephrine; Evaluation St | 1988 |
Risk factors for severe bradycardia during oral clonidine therapy for hypertension.
Topics: Administration, Oral; Aged; Bradycardia; Clonidine; Electrocardiography; Female; Humans; Hypertensio | 1988 |
[Transdermal treatment of hypertension].
Topics: Administration, Cutaneous; Antihypertensive Agents; Clonidine; Humans; Hypertension | 1988 |
Naloxone-induced hypertension in patients on clonidine.
Topics: Clonidine; Humans; Hypertension; Naloxone | 1988 |
[Comparative evaluation of sublingual and intravenous administration of clopheline in arterial hypertension].
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; In | 1987 |
Clonidine therapy for alcohol withdrawal.
Topics: Carbamazepine; Clonidine; Diarrhea; Drug Therapy, Combination; Ethanol; Humans; Hyperhidrosis; Hyper | 1986 |
Treatment of clonidine rebound syndrome with sublingual captopril.
Topics: Administration, Oral; Angina Pectoris; Blood Pressure; Captopril; Clonidine; Female; Heart Rate; Hum | 1986 |
Diuretic treatment alters clonidine suppression of plasma norepinephrine.
Topics: Administration, Oral; Amiloride; Blood Glucose; Blood Pressure; Body Weight; Clonidine; Drug Interac | 1986 |
Effect of clonidine on insulin secretion: a case report.
Topics: Blood Glucose; Clonidine; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Insulin; Insulin | 1986 |
Management of urgent hypertension: a comparison of oral treatment regimens in the emergency department.
Topics: Administration, Oral; Antihypertensive Agents; Captopril; Clonidine; Drug Administration Schedule; E | 1986 |
Calcium antagonists: interactions in hypertension.
Topics: Adult; Blood Pressure; Clonidine; Drug Interactions; Female; Humans; Hypertension; Indomethacin; Mal | 1986 |
Transdermal clonidine for the treatment of essential hypertension.
Topics: Administration, Cutaneous; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Age | 1987 |
Effectiveness of sublingual clonidine in patients unable to take oral medication.
Topics: Administration, Oral; Aged; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1987 |
[Pharmacodynamic interaction of clonidine and nifedipine].
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Clonidine; Diastole; Drug Interactions; Female; Heart R | 1987 |
Effect of water deprivation on the centrally-mediated hypertensive response to clonidine in freely moving, normotensive rats.
Topics: Animals; Blood Pressure; Clonidine; Dehydration; Hypertension; Injections, Intravenous; Injections, | 1987 |
Production and reversal of DOCA-salt hypertension in baboons.
Topics: Animals; Atenolol; Biofeedback, Psychology; Clonidine; Desoxycorticosterone; Disease Models, Animal; | 1987 |
Role of the sympathetic nervous system in the maintenance of hypertension in rats harboring pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Animals; Chlorisondamine; Clonidine; Hypertension; Naloxone; Pheochromocyto | 1987 |
Alpine anesthesia: can pretreatment with clonidine decrease the peaks and valleys?
Topics: Anesthesia, General; Clonidine; Humans; Hypertension; Preanesthetic Medication; Tachycardia | 1987 |
Hypertension caused by clonidine in patients with diabetic autonomic neuropathy.
Topics: Autonomic Nervous System Diseases; Clonidine; Diabetic Neuropathies; Humans; Hypertension | 1987 |
[Characteristics of the course of arterial hypertension during long-term treatment with clonidine].
Topics: Blood Pressure; Clonidine; Humans; Hypertension; Time Factors | 1987 |
Effect of prolonged clonidine treatment and its withdrawal on noradrenaline turnover in the cerebral cortex and medulla oblongata of the spontaneously hypertensive rat.
Topics: Animals; Body Weight; Cerebral Cortex; Clonidine; Hypertension; Male; Medulla Oblongata; Methoxyhydr | 1987 |
Kinetics of transdermal clonidine.
Topics: Clonidine; Humans; Hypertension; Kinetics; Liver; Skin | 1987 |
Hypertensive emergencies.
Topics: Adrenal Gland Neoplasms; Angina Pectoris; Antihypertensive Agents; Aortic Aneurysm; Aortic Dissectio | 1986 |
[Catapressan].
Topics: Clonidine; Humans; Hypertension | 1986 |
Clinical parameters of adolescent Hispanic male hypertensive subjects: a new subject?
Topics: Adolescent; Clonidine; Electrocardiography; Exercise Test; Female; Florida; Hispanic or Latino; Huma | 1987 |
[Sublingual clonidine in hypertensive crises].
Topics: Administration, Sublingual; Adult; Aged; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1987 |
Oral clonidine for rapid control of accelerated hypertension.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Time Factors | 1987 |
Dietary salt intake and the clonidine suppression test.
Topics: Adult; Aging; Body Weight; Cardiography, Impedance; Catecholamines; Clonidine; Humans; Hypertension; | 1987 |
Participation of GABAergic mechanisms in the hypotensive and bradycardic effects of clonidine: experimental study in conscious normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Desoxycorticosterone; gamma-Aminobutyric Acid; Heart Rate; Hyper | 1987 |
The efficacy of a transdermal formulation of clonidine in mild to moderate hypertension and its effects on the arterial and venous vasculature of the forearm.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Clonidine; Female; Forearm; Heart Rate; Huma | 1987 |
Clonidine fails to reduce pressor responsiveness of conscious spontaneously hypertensive rats to vasopressin.
Topics: Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male | 1986 |
[Clinico-therapeutic evaluation of the hypertensive patient by the isometric exertion test].
Topics: Adult; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidone; Clonidine; Female; Humans; | 1986 |
Tachycardic and hypertensive effects of centrally administered clonidine in conscious rats.
Topics: Animals; Atropine; Blood Pressure; Bradycardia; Clonidine; Heart Rate; Hypertension; Hypotension; In | 1986 |
[Use of clonidine in the prevention of intraoperative hypertensive crisis. Study on cardiopathic and hypertensive patients subjected to cataract surgery under local anesthesia].
Topics: Aged; Anesthesia, Local; Cataract Extraction; Clonidine; Female; Heart Diseases; Humans; Hypertensio | 1986 |
Effects of clonidine on central and peripheral nerve tone in primary hypertension.
Topics: Adult; Aged; Blood Pressure; Clonidine; Dopamine; Epinephrine; Female; Homovanillic Acid; Humans; Hy | 1986 |
[Use of clofeline in arterial hypertension in diabetes mellitus].
Topics: Adult; Aged; Antihypertensive Agents; Clonidine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 1986 |
Modification of clonidine-induced pressor responses in morphine-dependent and hypophysectomised rats.
Topics: Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Hypertension; Hypophysectomy; | 1986 |
Is clonidine a behavioural teratogen in the human?
Topics: Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Clonidine; Dose-Response Rel | 1986 |
A low dietary sodium intake reduces neuronal noradrenaline release and the blood pressure in spontaneously hypertensive rats.
Topics: Animals; Catecholamines; Clonidine; Decerebrate State; Diet, Sodium-Restricted; Electric Stimulation | 1986 |
Autonomic dysreflexia in a paraplegic man with catecholamine-secreting neuroblastoma.
Topics: Adult; Autonomic Nervous System Diseases; Catecholamines; Clonidine; Humans; Hypertension; Male; Neu | 1986 |
[Regression of left heart hypertrophy with clonidine. Prevention of hypertensive heart disease].
Topics: Blood Pressure; Cardiac Volume; Cardiomyopathy, Hypertrophic; Clonidine; Humans; Hypertension | 1986 |
An intracerebroventricular perfusion system developed for the study of centrally acting antihypertensive drugs in the rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Catheters, Indwelling; Cerebral Ventricles; Clonid | 1986 |
Rebound hypertension associated with transdermal clonidine and contact dermatitis.
Topics: Administration, Topical; Aged; Clonidine; Dermatitis, Contact; Female; Humans; Hypertension; Recurre | 1986 |
Reversal of clonidine toxicity by naloxone.
Topics: Accidents, Traffic; Aged; Clonidine; Female; Humans; Hypertension; Hypotension; Myocardial Infarctio | 1986 |
[Use of clonidine in the treatment of opiate withdrawal syndrome].
Topics: Adult; Clonidine; Female; Humans; Hypertension; Middle Aged; Opium; Substance Withdrawal Syndrome | 1986 |
Central inhibition of sympathetic overdrive by clonidine in acute myocardial infarction with systolic hypertension. Haemodynamic study.
Topics: Aged; Blood Pressure; Cardiac Output; Catecholamines; Clonidine; Female; Hemodynamics; Humans; Hyper | 1986 |
[Clonidine and treatment of arterial hypertension in the pregnant woman].
Topics: Adult; Clonidine; Female; Humans; Hypertension; Pregnancy; Pregnancy Complications, Cardiovascular | 1986 |
Hypertensive emergencies treated with oral clonidine.
Topics: Adult; Clonidine; Emergencies; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged | 1986 |
Rebound hypertension following abrupt cessation of clonidine and metoprolol. Treatment with labetalol.
Topics: Aged; Clonidine; Humans; Hypertension; Labetalol; Male; Metoprolol; Substance Withdrawal Syndrome | 1987 |
Oral substitution in patients sensitized by transdermal clonidine treatment.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Clonidine; Dermatitis, Contact; Female | 1987 |
Pharmacokinetics of clonidine during pregnancy and nursing.
Topics: Amniotic Fluid; Breast Feeding; Clonidine; Female; Fetal Blood; Humans; Hypertension; Infant, Newbor | 1987 |
[Comparative evaluation in the treatment of arterial hypertension between prolonged-action clonidine and atenolol].
Topics: Adult; Aged; Atenolol; Clonidine; Delayed-Action Preparations; Female; Humans; Hypertension; Male; M | 1985 |
Tissue distribution of endralazine and its clinical effect in refractory hypertension.
Topics: Animals; Antihypertensive Agents; Autoradiography; Blood Pressure; Carbon Radioisotopes; Clonidine; | 1985 |
The use of transcutaneous clonidine hydrochloride in the patient with diabetes mellitus and mild hypertension.
Topics: Administration, Topical; Adult; Clonidine; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; | 1985 |
Clonidine in the treatment of hypertension during pregnancy.
Topics: Adult; Clonidine; Female; Fetal Death; Humans; Hypertension; Pre-Eclampsia; Pregnancy; Pregnancy Com | 1985 |
Blood pressure normalization restores normal renal prostaglandin production in essential hypertension.
Topics: Adult; Blood Pressure; Clonidine; Diet, Sodium-Restricted; Dinoprostone; Female; Humans; Hypertensio | 1985 |
Transdermal clonidine in the treatment of adolescent hypertension.
Topics: Administration, Topical; Adolescent; Clonidine; Drug Evaluation; Female; Heart Rate; Humans; Hyperte | 1985 |
Treatment of hypertension by a new transdermal form of clonidine.
Topics: Adhesiveness; Administration, Oral; Administration, Topical; Aged; Clonidine; Dermatitis, Contact; D | 1985 |
Transdermal clonidine therapy in elderly mild hypertensives: effects on blood pressure, plasma norepinephrine and fasting plasma glucose.
Topics: Administration, Topical; Aged; Blood Glucose; Blood Pressure; Clonidine; Dermatitis, Contact; Female | 1985 |
Role of brain cholinergic system in the antihypertensive effect of clonidine in different models of rat hypertension.
Topics: Acetylcholine; Animals; Blood Pressure; Brain; Clonidine; Desoxycorticosterone; Disease Models, Anim | 1985 |
Drugs for hypertensive emergencies.
Topics: Administration, Oral; Captopril; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hypertensio | 1985 |
Effect of clonidine on glucose, insulin and glucagon responses to a protein meal in type 2 diabetics.
Topics: Adult; Aged; Blood Glucose; Clonidine; Diabetes Mellitus, Type 2; Dietary Proteins; Female; Food; Gl | 1985 |
[Hyperglycemia and arterial hypertension on severe acute hepatic insufficiency].
Topics: Acute Disease; Clonidine; Female; Hepatitis, Viral, Human; Humans; Hyperglycemia; Hypertension; Insu | 1985 |
Effects of clonidine and guanfacine on haemodynamics in hypertension.
Topics: Blood Pressure; Clonidine; Guanfacine; Guanidines; Humans; Hypertension; Phenylacetates | 1985 |
Cardiovascular and hormonal effects of clonidine in patients with essential hypertension and renal hypertension.
Topics: Adult; Aged; Blood Pressure; Clonidine; Heart Rate; Hemodynamics; Hormones; Humans; Hypertension; Hy | 1985 |
Transdermal clonidine.
Topics: Administration, Topical; Clonidine; Humans; Hypertension; Kinetics | 1986 |
[Clofeline chronotherapy of patients with essential hypertension].
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension | 1986 |
Discriminative stimuli produced by clonidine in spontaneously hypertensive rats: generalization to antihypertensive drugs with different mechanisms of action.
Topics: Animals; Antihypertensive Agents; Clonidine; Discrimination Learning; Dose-Response Relationship, Dr | 1985 |
Transdermal clonidine therapy in hypertensive patients. Effects on office and ambulatory recorded blood pressure values.
Topics: Administration, Topical; Adult; Blood Pressure; Blood Pressure Determination; Clonidine; Female; Hea | 1985 |
Clonidine suppression testing in essential hypertension.
Topics: Adult; Aging; Blood Pressure; Clonidine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged | 1985 |
Naloxone reverses the antinociceptive action of clonidine in spontaneously hypertensive rats.
Topics: Analgesia; Animals; Clonidine; Dose-Response Relationship, Drug; Drug Interactions; Hypertension; Ma | 1985 |
Clonidine. Quo vadis?
Topics: Adrenal Gland Neoplasms; Anxiety Disorders; Climacteric; Clonidine; Female; Humans; Hypertension; Mi | 1985 |
Association between hypoalgesia and hypertension in rats after short-term isolation.
Topics: Animals; Clonidine; Disease Models, Animal; Heart Rate; Hypertension; Male; Naloxone; Pain; Rats; Ra | 1985 |
Long term treatment with clonidine during the development of hypertension in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Disease Models, Animal; Hypertension; Male; Rats; Rats, Inbred S | 1985 |
An acute hypertensive response after intravenous use of a new pentazocine formulation.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Injections, Intravenous; Pentazocine; Substance-Rela | 1985 |
Clonidine can lower blood pressure by inhibiting vasopressin release.
Topics: Animals; Blood Pressure; Catecholamines; Chlorisondamine; Clonidine; Electric Stimulation; Heart Rat | 1985 |
Muzolimine in advanced chronic renal failure.
Topics: Acid-Base Imbalance; Acidosis; Adult; Aged; Clonidine; Diuresis; Edema; Female; Glomerular Filtratio | 1985 |
Hypertension in pregnancy. A study of 142 women presenting before 32 weeks' gestation.
Topics: Antihypertensive Agents; Clonidine; Diazoxide; Female; Humans; Hydralazine; Hypertension; Infant Mor | 1985 |
[Scintigraphy with 131I-metaiodobenzylguanidine in the differential diagnosis of pheochromocytoma].
Topics: 3-Iodobenzylguanidine; Adrenal Gland Neoplasms; Clonidine; Humans; Hypertension; Iodine Radioisotope | 1985 |
Hypertensive emergencies.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hyp | 1985 |
[Therapy of arterial hypertension with a delayed-action clonidine and chlorthalidone combination].
Topics: Adult; Aged; Chlorthalidone; Clonidine; Delayed-Action Preparations; Drug Combinations; Female; Huma | 1985 |
Enhanced depressor effect of muscimol in the DOCA/NaCl hypertensive rat: evidence for altered GABAergic activity in brain.
Topics: Animals; Bicuculline; Blood Pressure; Brain Chemistry; Clonidine; Desoxycorticosterone; Drug Interac | 1985 |
Preliminary results with the clonidine suppression test in the diagnosis of pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Clonidine; Diagnosis, Differential; Epinephrine; Humans; Hypertension; Nore | 1985 |
Regimen for the control of blood pressure and symptoms during clonidine withdrawal.
Topics: Adult; Aged; Atenolol; Blood Pressure; Chlordiazepoxide; Clonidine; Female; Heart Rate; Humans; Hype | 1985 |
Transdermal clonidine for hypertension.
Topics: Administration, Topical; Clonidine; Costs and Cost Analysis; Humans; Hypertension; Kinetics | 1985 |
Transdermal clonidine in a patient with resistant hypertension and malabsorption.
Topics: Administration, Topical; Clonidine; Drug Resistance; Humans; Hypertension; Malabsorption Syndromes; | 1985 |
Acute tolerance to clonidine hypotension and bradycardia in normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Drug Tolerance; Heart Rate; Hypertension; Male; Rats; Rats, Inbr | 1985 |
[Effect of antihypertensive therapy with clonidine and alphamethyldopa on the indirect oxygen consumption index of the myocardium at rest and during exertion].
Topics: Adult; Clonidine; Hemodynamics; Humans; Hypertension; Male; Methyldopa; Middle Aged; Myocardium; Oxy | 1985 |
[Hemodynamic effects of clonidine in patients with stage III and IV hypertension].
Topics: Adult; Aged; Clonidine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged | 1985 |
Characterization of the rebound hypertension following withdrawal of clonidine treatment.
Topics: Animals; Clonidine; Dogs; Hypertension; Hypertension, Renal; In Vitro Techniques; Rats; Substance Wi | 1985 |
Comparison between osmotic mini-pumps and controlled release pellets in chronic clonidine administration in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Clonidine; Delayed-Action Preparations; Hypertension; Rats; Rats, Inbred SH | 1985 |
Interaction between clonidine and alpha blockers.
Topics: Animals; Blood Pressure; Clonidine; Drug Interactions; Drug Therapy, Combination; Humans; Hypertensi | 1985 |
Reduced transcapillary escape of albumin during acute blood pressure-lowering in type 1 (insulin-dependent) diabetic patients with nephropathy.
Topics: Adult; Blood Glucose; Capillary Permeability; Clonidine; Diabetes Mellitus, Type 1; Diabetic Angiopa | 1985 |
Letter: Withdrawal of antihypertensive therapy.
Topics: Blood Pressure; Clonidine; Humans; Hypertension; Phentolamine; Propranolol | 1974 |
Letter: Withdrawal of antihypertensive therapy.
Topics: Clonidine; Heart Arrest; Humans; Hypertension; Male; Middle Aged; Substance Withdrawal Syndrome | 1974 |
[New antihypertensive drugs].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Clopamide; Debrisoquin; Drug Synerg | 1972 |
Action of -adrenergic blocking drugs on the sympathetic centres and their interactions with the central sympatho-inhibitory effect of clonidine.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Circulation; Blood Pressure; Cats; Cisterna Magna; Clon | 1973 |
Management of severe hypertension.
Topics: Benzothiadiazines; Blood Pressure; Clonidine; Diazoxide; Diet, Sodium-Restricted; Disseminated Intra | 1973 |
[The treatment of arterial hypertension associated with renal insufficiency].
Topics: Clonidine; Diuretics; Ganglionic Blockers; Guanethidine; Humans; Hydralazine; Hypertension; Kidney F | 1973 |
[Pharmacological basis of the symptomatic treatment of arterial hypertension. I. Hemodynamic effects, mechanisms of action and side effects of antihypertensive agents].
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Diuretics; Ganglionic | 1973 |
[Practical medical treatment of essential arterial hypertension].
Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Clonidine; Diuretics; Drug Combin | 1973 |
[Letter: Diet and drugs in arterial hypertension].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Clonidine; Diet, Sodium-Restricted; Diure | 1974 |
Blood pressure over-shoot due to acute clonidine (Catapres) withdrawal: studies on arterial and urinary catecholamines and suggestions for management of the crisis.
Topics: Acetanilides; Adrenergic beta-Antagonists; Amino Alcohols; Catecholamines; Clonidine; Headache; Huma | 1973 |
Inhibition of adrenergic function in the treatment of hypertension.
Topics: Antihypertensive Agents; Autonomic Agents; Bretylium Compounds; Clonidine; Depression, Chemical; Gan | 1974 |
[Differential therapeutic principles in the drug therapy of high blood pressure].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Cardiac Vol | 1974 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; | 1974 |
[Pharmacological basis of the symptomatic treatment of arterial hypertension. II. Antihypertensive agent combinations].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Drug Antagoni | 1973 |
[General principles of antihypertensive treatment].
Topics: Antihypertensive Agents; Cardiac Output; Clonidine; Follow-Up Studies; Ganglionic Blockers; Guanethi | 1974 |
Treatment of hypertension in the elderly.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Clonidine; Di | 1974 |
A standard approach to therapy.
Topics: Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Ganglionic Blockers; Guanethidine; | 1974 |
Adrenolytic and vasodilator therapy.
Topics: Adrenergic beta-Antagonists; Benzyl Compounds; Blood Circulation; Cardiac Output; Clonidine; Diazoxi | 1974 |
Renin suppression.
Topics: Adrenergic beta-Antagonists; Clonidine; Humans; Hypertension; Methyldopa; Renin; Reserpine; Sodium | 1974 |
Catecholamine uptake sites in the rat heart after 6-hydroxydopamine treatment and in a genetically hypertensive strain.
Topics: Animals; Catecholamines; Clonidine; Corticosterone; Heart; Hydroxydopamines; Hypertension; In Vitro | 1973 |
[How to advance antihypertensive therapy].
Topics: Adult; Angiotensin II; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Clonidine; Humans; Hy | 1974 |
[Current status of diagnosis and treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Guanethidine; Humans; Hy | 1972 |
Antihypertensive activity of four blocking agents in spontaneously hypertensive rats.
Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Antihypertensive Agents; Blood Pressure; Clonidine | 1972 |
Effects of clonidine therapy on exchangeable sodium and renal hemodynamics in essential hypertension.
Topics: Adult; Aminohippuric Acids; Blood Pressure; Blood Urea Nitrogen; Clonidine; Creatinine; Female; Glom | 1974 |
[Catapresan and anesthesia. Complications illustrated by a case].
Topics: Anesthesia; Clonidine; Humans; Hypertension; Male; Middle Aged; Neuroleptanalgesia | 1974 |
[Catapresan (Clonidine) in hypertension].
Topics: Administration, Oral; Clonidine; Humans; Hypertension; Injections | 1974 |
Effect of clonidine on sympathetic discharge rate of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Clonidine; Electric Stimulation; Heart Rate; Hypertension; Injections, Intr | 1974 |
[Results of the clinical use of catapressan in arterial hypertension].
Topics: Clonidine; Drug Evaluation; Female; Humans; Hypertension; Male; Time Factors | 1974 |
Proceedings: The production of hypertension and the effects of some antihypertensive agents in the conscious unrestrained cat.
Topics: Animals; Antihypertensive Agents; Cats; Cellophane; Clonidine; Corticosterone; Delayed-Action Prepar | 1974 |
[Possibilities and limitations of hypertensive therapy].
Topics: Clonidine; Drug Therapy, Combination; Guanethidine; Humans; Hydralazine; Hypertension; Methyldopa; R | 1974 |
Letter: A critical survey of drugs used in the treatment of hypertensive crises of pregnancy.
Topics: Adult; Clonidine; Female; Humans; Hypertension; Obstetric Labor Complications; Pregnancy; Puerperal | 1974 |
[Critical exertion pressure in patients with hypertension. Results of direct blood-pressure measurement under everyday and ergometric stress conditions, conclusions for the practice].
Topics: Adult; Blood Pressure; Blood Pressure Determination; Clonidine; Exercise Test; Female; Guanethidine; | 1974 |
[Evaluation of the clinical effectiveness of clonidine used alone and in combination with a diuretic or methylodopa].
Topics: Adult; Benzothiadiazines; Clonidine; Diuretics; Drug Evaluation; Drug Therapy, Combination; Humans; | 1974 |
[Treatment of arterial hypertension with propranolol: our experience].
Topics: Clonidine; Drug Therapy, Combination; Humans; Hypertension; Propranolol | 1974 |
Editorial: Hypertension and depression and their treatment.
Topics: Animals; Antidepressive Agents; Antihypertensive Agents; Clonidine; Depression; Humans; Hypertension | 1973 |
The effect of clonidine on plasma renin activity in human hypertension.
Topics: Adult; Body Weight; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Oxprenolol; Phentola | 1973 |
[Letter: Effect of injectable clonidine on renin secretion in essential arterial hypertension].
Topics: Clonidine; Humans; Hypertension; Indicator Dilution Techniques; Injections, Intravenous; Regional Bl | 1974 |
[Hemodynamics and anti-hypertensive treatment].
Topics: Antihypertensive Agents; Clonidine; Diuretics; Guanethidine; Hemodynamics; Humans; Hypertension; Met | 1972 |
[Principles and management of antihypertensive treatment].
Topics: Antihypertensive Agents; Carotid Sinus; Clonidine; Electric Stimulation; Ferricyanides; Guanethidine | 1972 |
[Treatment of arterial hypertension with new drugs. 1. Severe arterial hypertension].
Topics: Antihypertensive Agents; Body Weight; Clonidine; Diuresis; Furosemide; Hemodynamics; Humans; Hyperte | 1972 |
[Intraocular pressure, blood pressure, and glaucoma damage. Comparative perimetric studies on the relationship between the increase of intraocular pressure, blood sedimentation, and visual-field disorders in primary glaucoma].
Topics: Acetazolamide; Adult; Aged; Analysis of Variance; Blood Pressure; Clonidine; Female; Glaucoma; Human | 1972 |
The effect of insulin induced hypoglycaemia on plasma renin activity and urinary catecholamines before and following clonidine (Catapresan) in man.
Topics: Adult; Aged; Blood Glucose; Clonidine; Depression, Chemical; Epinephrine; Female; Humans; Hypertensi | 1972 |
The role of central and peripheral mechanisms in the maintenance of experimental hypertension in the rabbit.
Topics: Animals; Blood Pressure; Clonidine; Hypertension; Hypertension, Renal; Rabbits; Sympathetic Nervous | 1973 |
Effects of clonidine withdrawal: possible mechanisms and suggestions for management.
Topics: Blood Pressure; Catecholamines; Clonidine; Epinephrine; Heart Rate; Humans; Hypertension; Injections | 1973 |
Clonidine in the treatment of severe hypertension.
Topics: Adult; Anesthesia, General; Cerebrovascular Disorders; Clonidine; Coronary Disease; Depression; Huma | 1973 |
[Hypotensive response to parenteral administration of clonidine in hypertensive patients].
Topics: Adult; Aged; Blood Pressure; Clonidine; Evaluation Studies as Topic; Female; Heart Rate; Humans; Hyp | 1973 |
Clonidine.
Topics: Clonidine; Drug Interactions; Humans; Hypertension | 1973 |
[Catapressan in diabetics and the hypertensive obese. Study of glucose regulation].
Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Clonidine; Diabetes Complications; Female; Humans; Hy | 1973 |
[Medical treatment of arterial hypertension in adults].
Topics: Adult; Antihypertensive Agents; Clonidine; Diet, Sodium-Restricted; Guanethidine; Humans; Hydrazines | 1973 |
Hypertension.
Topics: Antihypertensive Agents; Body Weight; Clonidine; Humans; Hypertension; Methyldopa; Propranolol; Smok | 1973 |
[Hypertension: 3 H-catecholamine metabolism in the adrenal glands and brain and tissue metabolism of 3 3 H-DOPA during reserpine, alpha-methyl DOPA and ST-155 administration in spontaneously hypertensive rats].
Topics: Adrenal Glands; Animals; Blood Pressure; Body Weight; Brain; Catecholamines; Clonidine; Dihydroxyphe | 1973 |
Pancreatitis during clonidine treatment.
Topics: Clonidine; Female; Humans; Hypertension; Middle Aged; Pancreatitis; Retrospective Studies | 1973 |
[The influence of clonidin (isoglaucon) eyedrops on blood pressure, intraocular pressure and cerebral blood flow in healthy persons, hypertonic and glaucoma patients (author's transl)].
Topics: Administration, Topical; Arterial Occlusive Diseases; Arteriosclerosis; Blood Pressure; Cerebrovascu | 1973 |
Central and peripheral mechanisms in the maintenance of experimental hypertension in the rabbit.
Topics: Anesthesia; Animals; Aorta; Carotid Sinus; Cellophane; Central Nervous System; Cisterna Magna; Cloni | 1973 |
[Comparative studies on the clonidine effect in long-term therapy of essential hypertension].
Topics: Clonidine; Humans; Hypertension; Time Factors | 1973 |
[Effects of clonidine treatment in advanced forms of essential arterial hypertension].
Topics: Aged; Aortic Arch Syndromes; Bradycardia; Cerebral Hemorrhage; Chemical Phenomena; Chemistry; Chlort | 1973 |
[Clinical study of a new product with hypotensive action: 2-(2,6-dichlorophenylamino)-2-imidazoline hydrochloride].
Topics: Adult; Aged; Arteriosclerosis; Clonidine; Female; Humans; Hypertension; Hypertension, Renal; Male; M | 1973 |
[Catapresan (hemiton) in the treatment of hypertension].
Topics: Adult; Aged; Clonidine; Hemodynamics; Humans; Hypertension; Hypertension, Renal; Middle Aged | 1973 |
Drugs used in the treatment of hypertension.
Topics: Administration, Oral; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ethacrynic Acid; Fer | 1973 |
Treatment of severe hypertension and hypertensive emergencies with intravenous clonidine hydrochloride.
Topics: Adult; Aged; Clonidine; Female; Heart Rate; Humans; Hypertension; Injections, Intravenous; Male; Mid | 1973 |
[The effect of prolonged treatment hypertensive rats with antihypertensive agents with different mechanisms of action on blood pressure and noradrenaline concentration in the myocardium, brain and aorta].
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Brain Chemistry; Clonidine; Disulfiram; Fur | 1973 |
Letter: Clonidine in hypertension.
Topics: Clonidine; Humans; Hypertension | 1974 |
[Anti-hypertensive action of 3 drugs inhibiting the sympathetic nervous system. Hemodynamic and biological study].
Topics: Adult; Clonidine; Female; Hemodynamics; Humans; Hypertension; Male; Methyldopa; Middle Aged; Plasma | 1974 |
The Clonidine side effect in the human eye.
Topics: Adult; Aged; Animals; Clonidine; Color Perception; Dark Adaptation; Electrooculography; Eye; Female; | 1974 |
Management of acute hypertensive crises with clonidine (Catapres).
Topics: Acute Disease; Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Injections, Int | 1974 |
[Clonidine: clinical and pharmacological studies and therapeutic applications in internal medicine].
Topics: Blood Circulation; Blood Pressure; Clonidine; Humans; Hypertension | 1974 |
[Clinical experimentation with a new anti-hypertensive agent (St 155)].
Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Clonidine; Evaluation Studies as Topic; Fema | 1972 |
Comparison of clonidine and methyldopa on blood pressure and side effects in hypertensive patients.
Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Heart Rate; Humans; Hypertension; Imidazoles; Me | 1972 |
[Water-sodium depletion and clonidine in severe arterial hypertension].
Topics: Adult; Antihypertensive Agents; Body Weight; Clonidine; Creatinine; Drug Synergism; Electrocardiogra | 1972 |
[Antihypertensive therapy].
Topics: Adult; Antihypertensive Agents; Clonidine; Diuretics; Drug Interactions; Female; Humans; Hydralazine | 1972 |
Prolonged treatment with clonidine: comparative antihypertensive effects alone and with a diuretic agent.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Clonidine; District of Columbia; Diuretics; Female; Fol | 1972 |
[Clonidine].
Topics: Animals; Antihypertensive Agents; Cats; Clonidine; Dogs; Humans; Hypertension; Imidazoles; Rabbits; | 1971 |
[Studies on the effect of clonidine on central, peripheral and renal hemodynamic as well as on peripheral and renovenous renin activity].
Topics: Clonidine; Hemodynamics; Humans; Hypertension; Juxtaglomerular Apparatus; Kidney; Renin | 1971 |
[Long-term treatment of hypertension with chlofazoline].
Topics: Adult; Aged; Clonidine; Female; Humans; Hypertension; Male; Middle Aged | 1971 |