clonidine has been researched along with Hypercapnia in 9 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypoxia or hypercapnia elicits cardiovascular responses associated with increased plasma catecholamine concentrations, whereas clonidine, an alpha(2)- adrenergic agonist, decreases plasma catecholamine concentrations." | 7.69 | Clonidine modulation of hemodynamic and catecholamine responses associated with hypoxia or hypercapnia in dogs. ( Naito, H; Nishikawa, T, 1996) |
| " The aim of the current study was to determine the effects of clonidine premedication on the ventilatory response to hypercapnia during sevoflurane anesthesia using the carbon dioxide (CO(2)) steady state method." | 5.11 | Oral clonidine does not change ventilatory response to carbon dioxide in sevoflurane-anesthetized children. ( Mikawa, K; Nishina, K; Obara, H; Uesugi, T, 2004) |
| "Systemic dexmedetomidine (DXM) attenuates the cerebral vasodilation induced by hypercapnia and decreases the cerebral blood flow response to hypoxia." | 3.70 | Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits. ( Dohi, S; Iida, H; Iida, M; Takenaka, M, 2000) |
| "Hypoxia or hypercapnia elicits cardiovascular responses associated with increased plasma catecholamine concentrations, whereas clonidine, an alpha(2)- adrenergic agonist, decreases plasma catecholamine concentrations." | 3.69 | Clonidine modulation of hemodynamic and catecholamine responses associated with hypoxia or hypercapnia in dogs. ( Naito, H; Nishikawa, T, 1996) |
| "Pretreatment with neostigmine completely prevented the clonidine-induced attenuation of the hypercapnic cerebral vasodilation attenuated by intrathecal clonidine (16% +/- 7%, 15% +/- 6%, 12% +/- 6%, and 16% +/- 8%, respectively)." | 1.33 | Intrathecal neostigmine prevents intrathecal clonidine from attenuating hypercapnic cerebral vasodilation in rabbits. ( Dohi, S; Iida, H; Iida, M; Kumazawa, M; Sumi, K; Takenaka, M; Tanahashi, S, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uchida, M | 1 |
| Iida, H | 3 |
| Osawa, Y | 1 |
| Tanahashi, S | 2 |
| Kumazawa, M | 2 |
| Sumi, K | 2 |
| Dohi, S | 3 |
| Nishina, K | 1 |
| Mikawa, K | 1 |
| Uesugi, T | 1 |
| Obara, H | 1 |
| Takenaka, M | 2 |
| Iida, M | 2 |
| Hedrick, MS | 1 |
| Ryan, ML | 1 |
| Pizarro, J | 1 |
| Bisgard, GE | 2 |
| Nishikawa, T | 1 |
| Naito, H | 1 |
| Maekawa, T | 1 |
| Cho, S | 1 |
| Fukusaki, M | 1 |
| Shibata, O | 1 |
| Sumikawa, K | 1 |
| O'Halloran, KD | 1 |
| Herman, JK | 1 |
| Sjöstrand, NO | 1 |
| Klinge, E | 1 |
3 trials available for clonidine and Hypercapnia
| Article | Year |
|---|---|
Clonidine attenuates the hemodynamic responses to hypercapnia during propofol anesthesia.
Topics: Adult; Analgesics; Anesthetics, Intravenous; Clonidine; Drug Synergism; Hemodynamics; Humans; Hyperc | 2004 |
Oral clonidine does not change ventilatory response to carbon dioxide in sevoflurane-anesthetized children.
Topics: Administration, Oral; Adolescent; Analgesics; Analysis of Variance; Anesthetics, Inhalation; Carbon | 2004 |
Effects of clonidine on human middle cerebral artery flow velocity and cerebrovascular CO2 response during sevoflurane anesthesia.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Anesthesia, Inhalation; Anesthetics, Inhalation; Bl | 1999 |
6 other studies available for clonidine and Hypercapnia
| Article | Year |
|---|---|
Intrathecal neostigmine prevents intrathecal clonidine from attenuating hypercapnic cerebral vasodilation in rabbits.
Topics: Adrenergic alpha-Agonists; Anesthesia; Animals; Arterioles; Cerebrovascular Circulation; Cholinester | 2005 |
Modulation of respiratory rhythm by alpha 2-adrenoceptors in awake and anesthetized goats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Antagonists; Anesthesia; Animals; Benzazepine | 1994 |
Clonidine modulation of hemodynamic and catecholamine responses associated with hypoxia or hypercapnia in dogs.
Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Clonidine; Dogs; Female; Hemodynamics; Hypercapn | 1996 |
Intrathecal dexmedetomidine attenuates hypercapnic but not hypoxic cerebral vasodilation in anesthetized rabbits.
Topics: Adjuvants, Anesthesia; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagoni | 2000 |
Ventilatory effects of alpha2-adrenoceptor blockade in awake goats.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzazepines; Blood Pressure; Caro | 2001 |
Changes in penile volume during some cardiovascular reflexes and reactions in rabbit.
Topics: Animals; Arteries; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Ch | 1979 |