clonidine has been researched along with Hemorrhagic Shock in 7 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Male Sprague-Dawley rats underwent 6 days of restraint stress after lung contusion/hemorrhagic shock during which the animals received clonidine (75 μg/kg) after the restraint stress." | 7.85 | Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Mohr, AM; Ramos, H, 2017) |
| "To study the effect of clonidine pre-treatment on hemorrhagic shock (H/S)-induced endotoxemia and oxidative stress (OS) in three vital organs of the rat." | 7.78 | Clonidine pre-treatment prevents hemorrhagic shock-induced endotoxemia and oxidative stress in the gut, liver, and lungs of the rat. ( Filos, KS; Fligou, F; Georgiou, C; Panteli, ES; Papamichail, C; Papapostolou, I; Spiliopoulou, I; Zervoudakis, G, 2012) |
| "Male Sprague-Dawley rats were allocated to naïve control, lung contusion followed by hemorrhagic shock (LCHS), or LCHS plus daily chronic restraint stress (LCHS/CS) ±propranolol, ±clonidine." | 3.91 | The effects of propranolol and clonidine on bone marrow expression of hematopoietic cytokines following trauma and chronic stress. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Millar, JK; Miller, ES; Mohr, AM, 2019) |
| "Male Sprague-Dawley rats underwent 6 days of restraint stress after lung contusion/hemorrhagic shock during which the animals received clonidine (75 μg/kg) after the restraint stress." | 3.85 | Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Mohr, AM; Ramos, H, 2017) |
| "Propranolol and clonidine were administered by daily intraperitoneal injection until sacrifice on day seven." | 1.56 | Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress. ( Brakenridge, SC; Efron, PA; Kannan, KB; Loftus, TJ; Mira, JC; Mohr, AM, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Loftus, TJ | 3 |
| Kannan, KB | 3 |
| Mira, JC | 1 |
| Brakenridge, SC | 1 |
| Efron, PA | 3 |
| Mohr, AM | 3 |
| Miller, ES | 1 |
| Millar, JK | 1 |
| Alamo, IG | 2 |
| Ramos, H | 1 |
| Filos, KS | 1 |
| Panteli, ES | 1 |
| Fligou, F | 1 |
| Papamichail, C | 1 |
| Papapostolou, I | 1 |
| Zervoudakis, G | 1 |
| Spiliopoulou, I | 1 |
| Georgiou, C | 1 |
| Zaloga, GP | 1 |
| Hostinsky, C | 1 |
| Chernow, B | 1 |
| Xie, CW | 1 |
| Han, JS | 1 |
| Deep, G | 1 |
| Singh, M | 1 |
1 review available for clonidine and Hemorrhagic Shock
| Article | Year |
|---|---|
Endogenous opioid peptides: critical care implications.
Topics: Animals; Body Temperature Regulation; Cardiovascular System; Clonidine; Endorphins; Halothane; Human | 1984 |
6 other studies available for clonidine and Hemorrhagic Shock
| Article | Year |
|---|---|
Modulation of the HGF/c-Met Axis Impacts Prolonged Hematopoietic Progenitor Mobilization Following Trauma and Chronic Stress.
Topics: Animals; Clonidine; Corticosterone; Enzyme-Linked Immunosorbent Assay; Hematopoietic Stem Cells; Hep | 2020 |
The effects of propranolol and clonidine on bone marrow expression of hematopoietic cytokines following trauma and chronic stress.
Topics: Anemia; Animals; Biomarkers; Bone Marrow; Chronic Disease; Clonidine; Contusions; Cytokines; Drug Th | 2019 |
Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress.
Topics: Animals; Bone Marrow; Chronic Disease; Clonidine; Contusions; Disease Models, Animal; Granulocyte Co | 2017 |
Clonidine pre-treatment prevents hemorrhagic shock-induced endotoxemia and oxidative stress in the gut, liver, and lungs of the rat.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Abdominal; Bacterial Translocation; Clonidine; Endotoxemi | 2012 |
[Alpha-adrenoceptors in the rat spinal cord: its role in baroreflex and hemorrhagic shock].
Topics: Animals; Clonidine; Female; Injections, Spinal; Male; Phentolamine; Pressoreceptors; Rats; Receptors | 1986 |
Modulation of cardiovascular reactivity with calcium channel blockers in rats subjected to haemorrhagic shock.
Topics: Angiotensins; Animals; Calcium Channel Blockers; Clonidine; Epinephrine; Female; Hemodynamics; Male; | 1986 |