clonidine has been researched along with Headache Disorders in 5 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Headache Disorders: Various conditions with the symptom of HEADACHE. Headache disorders are classified into major groups, such as PRIMARY HEADACHE DISORDERS (based on characteristics of their headache symptoms) and SECONDARY HEADACHE DISORDERS (based on their etiologies). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tizanidine is an alpha2-adrenergic agonist that inhibits the release of norepinephrine at both the spinal cord and brain, with antinociceptive effects that are independent of the endogenous opioid system." | 2.70 | Chronic daily headache prophylaxis with tizanidine: a double-blind, placebo-controlled, multicenter outcome study. ( Cantrell, DT; Lake, AE; Saper, JR; White, JR; Winner, PK, 2002) |
| "Tizanidine hydrochloride is an alpha2-adrenergic agonist that inhibits the release and effectiveness of norepinephrine at both central sites (eg, the locus ceruleus) and the spinal cord." | 2.70 | An open-label dose-titration study of the efficacy and tolerability of tizanidine hydrochloride tablets in the prophylaxis of chronic daily headache. ( Lake, AE; Saper, JR; Winner, PK, 2001) |
| "Occipital neuralgia is the third most common headache syndrome after migraine and tension type headaches." | 1.48 | Transcutaneous Electrical Nerve Stimulation in Treatment of Occipital Neuralgia: A Case Report. ( Candido, KD; Ghaly, RF; Knezevic, NN; Plesca, A, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghaly, RF | 1 |
| Plesca, A | 1 |
| Candido, KD | 1 |
| Knezevic, NN | 1 |
| Saper, JR | 2 |
| Lake, AE | 2 |
| Cantrell, DT | 1 |
| Winner, PK | 2 |
| White, JR | 1 |
| Warner, JS | 1 |
| Smith, TR | 1 |
2 trials available for clonidine and Headache Disorders
| Article | Year |
|---|---|
Chronic daily headache prophylaxis with tizanidine: a double-blind, placebo-controlled, multicenter outcome study.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Chronic Disease; Clonidine; Double-Blind Method; Femal | 2002 |
An open-label dose-titration study of the efficacy and tolerability of tizanidine hydrochloride tablets in the prophylaxis of chronic daily headache.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Dose-Response Relationship, Drug; Fem | 2001 |
3 other studies available for clonidine and Headache Disorders
| Article | Year |
|---|---|
Transcutaneous Electrical Nerve Stimulation in Treatment of Occipital Neuralgia: A Case Report.
Topics: Adult; Analgesics; Clonidine; Female; Headache Disorders; Humans; Neck Pain; Neuralgia; Occipital Lo | 2018 |
Tizanidine is not a cure for chronic daily headache.
Topics: Adrenergic alpha-Agonists; Clinical Trials as Topic; Clonidine; Double-Blind Method; Headache Disord | 2003 |
Low-dose tizanidine with nonsteroidal anti-inflammatory drugs for detoxification from analgesic rebound headache.
Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clonidine; Dose-R | 2002 |