clonidine has been researched along with Chronic Primary Open Angle Glaucoma in 49 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes." | 9.34 | Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020) |
| "The authors compared the efficacy of apraclonidine 1% versus pilocarpine 4% prophylaxis of post-argon laser trabeculoplasty (ALT) intraocular pressure (IOP) spike." | 9.09 | Efficacy of apraclonidine 1% versus pilocarpine 4% for prophylaxis of intraocular pressure spike after argon laser trabeculoplasty. ( Birt, CM; Chung, HS; Glover, BK; Hughes, BA; Juzych, MS; Kim, C; Ren, J; Shin, DH, 1999) |
| "2% can control intraocular pressure (IOP) spikes as well as apraclonidine 1." | 9.09 | Control of intraocular pressure elevations after argon laser trabeculoplasty: comparison of brimonidine 0.2% to apraclonidine 1.0%. ( Barnes, SD; Campagna, JA; Dirks, MS; Doe, EA, 1999) |
| "A randomized, prospective, double-masked study was undertaken to determine the risk of postcycloplegic intraocular pressure spikes in patients with open-angle glaucoma and to evaluate apraclonidine prophylaxis in minimizing these spikes." | 9.07 | Apraclonidine prophylaxis for postcycloplegic intraocular pressure spikes. ( Baerveldt, G; Heuer, DK; Hill, RA; Lee, M; Martone, JF; Minckler, DS, 1991) |
| "To determine the incidence of intraocular pressure (IOP) rise of varying degrees after laser peripheral iridotomy (LPI) in patients with and without glaucoma treated perioperatively with pilocarpine and apraclonidine." | 7.70 | The rarity of clinically significant rise in intraocular pressure after laser peripheral iridotomy with apraclonidine. ( Gangnon, R; Heatley, GA; Kaufman, PL; Lewis, R; Perkins, TW, 1998) |
| "Intraocular pressure (IOP) measurements were carried out before and 1, 2 and 3 h after a single drop of apraclonidine." | 7.69 | Efficacy of apraclonidine ophthalmic solution (Iopidine) in presumed silicon oil-induced glaucoma and primary open-angle glaucoma. ( Busche, S; Gramer, E; Kampik, A; Parsons, D, 1995) |
| "0% apraclonidine in preventing intraocular pressure (IOP) spike after argon laser trabeculoplasty (ALT) in patients on chronic apraclonidine therapy compared with patients not on chronic apraclonidine use." | 7.69 | Chronic use of apraclonidine decreases its moderation of post-laser intraocular pressure spikes. ( Birt, CM; Chung, HS; Hakimzadeh, R; Juzych, MS; Kim, C; Lee, D; Levin, DS; Shin, DH, 1997) |
| "Apraclonidine 1." | 6.69 | Reversal of intraocular pressure increases with 0.5% apraclonidine after dilated fundus examination in patients with chronic open-angle glaucoma. ( Chang, FW; Kolin, T; Nishimoto, JH; Tang, IH, 1999) |
| "PRéCIS:: Adjuvant diclofenac and apraclonidine eye drop given in conjunction with selective laser trabeculoplasty (SLT) do not significantly impact medium-term intraocular pressure (IOP) reduction compared with placebo, but apraclonidine can be used to blunt immediate postlaser pressure spikes." | 5.34 | Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty. ( Bergo, C; Halvorsen, H; Krohn, J; Thrane, AS; Thrane, VR, 2020) |
| "2% topical medication or the replacement of apraclonidine with brimonidine resulted in a significant decrease in mean intraocular pressure from 20." | 5.09 | Long-term brimonidine therapy in glaucoma patients with apraclonidine allergy. ( Cha, SC; Glover, BK; Kim, C; Kim, YY; Nguyen, KD; Shin, DH, 1999) |
| "The authors compared the efficacy of apraclonidine 1% versus pilocarpine 4% prophylaxis of post-argon laser trabeculoplasty (ALT) intraocular pressure (IOP) spike." | 5.09 | Efficacy of apraclonidine 1% versus pilocarpine 4% for prophylaxis of intraocular pressure spike after argon laser trabeculoplasty. ( Birt, CM; Chung, HS; Glover, BK; Hughes, BA; Juzych, MS; Kim, C; Ren, J; Shin, DH, 1999) |
| "2% can control intraocular pressure (IOP) spikes as well as apraclonidine 1." | 5.09 | Control of intraocular pressure elevations after argon laser trabeculoplasty: comparison of brimonidine 0.2% to apraclonidine 1.0%. ( Barnes, SD; Campagna, JA; Dirks, MS; Doe, EA, 1999) |
| " Following the addition of apraclonidine the mean, peak and range of IOP were statistically similar between groups and only the standard deviations remained higher in the exfoliation glaucoma group (p < 0." | 5.09 | The comparative ocular hypotensive effect of apraclonidine with timolol maleate in exfoliation versus primary open-angle glaucoma patients. ( Konstas, AG; Maltezos, A; Mantziris, DA; Sine, CS; Stewart, WC, 1999) |
| "Fifty-two (60%) of 86 patients treated with apraclonidine maintained adequate intraocular pressure control throughout the study and avoided surgery, compared with 28 (32%) of 88 patients treated with placebo (P < ." | 5.08 | Short-term efficacy of apraclonidine hydrochloride added to maximum-tolerated medical therapy for glaucoma. Apraclonidine Maximum-Tolerated Medical Therapy Study Group. ( Lehmann, RP; Mundorf, T; Ritch, R; Robin, AL; Shin, DH; Smythe, B, 1995) |
| "We determined whether the addition of topical apraclonidine hydrochloride to eyes receiving maximal medical therapy, with inadequate intraocular pressure (IOP) control, and scheduled to undergo surgery, could adequately lower IOP, postponing the need for surgical intervention." | 5.08 | Topical apraclonidine hydrochloride in eyes with poorly controlled glaucoma. The Apraclonidine Maximum Tolerated Medical Therapy Study Group. ( Lehmann, RP; Mundorf, T; Ritch, R; Robin, AL; Shin, D; Smythe, B, 1995) |
| "Apraclonidine and pilocarpine have been shown to be effective in reducing the incidence of intraocular pressure (IOP) spikes following argon laser trabeculoplasty." | 5.07 | Influence of apraclonidine and pilocarpine alone and in combination on post laser trabeculoplasty pressure rise. ( Cunliffe, IA; Dapling, RB; Longstaff, S, 1994) |
| "Apraclonidine effectively lowers IOP associated with open-angle glaucoma or ocular hypertension; these pilot results will need to be confirmed by a larger pivotal study." | 5.07 | Comparison of apraclonidine and timolol in chronic open-angle glaucoma. A three-month study. ( Chuniaud, M; Demailly, P; Hitchings, RA; Nagasubramanian, S; Pannarale, MR; Parsons, DG; Pecori-Giraldi, J; Stodtmeister, R, 1993) |
| "Sixty patients with medically uncontrolled open-angle glaucoma (intraocular pressure greater than 21 mm Hg) were randomly assigned to one of two treatment regimens with apraclonidine before undergoing 360-degree argon laser trabeculoplasty." | 5.07 | Apraclonidine and argon laser trabeculoplasty. ( Brodstein, DE; Chase, RD; Chopra, H; Goldenfeld, M; Holmwood, PC; Krupin, T; Rosenberg, LF; Ruderman, JM; Tallman, BA, 1992) |
| "The short-term additive effect and side effects of adding 1% apraclonidine hydrochloride to nonselective beta-blockers were investigated in 21 patients with ocular hypertension or early primary open-angle glaucoma." | 5.07 | Additive effect of 1% apraclonidine hydrochloride to nonselective beta-blockers. ( Lee, SH; Lee, SY; Parrow, KA; Shin, DH; Yaldo, MK, 1991) |
| "A randomized, prospective, double-masked study was undertaken to determine the risk of postcycloplegic intraocular pressure spikes in patients with open-angle glaucoma and to evaluate apraclonidine prophylaxis in minimizing these spikes." | 5.07 | Apraclonidine prophylaxis for postcycloplegic intraocular pressure spikes. ( Baerveldt, G; Heuer, DK; Hill, RA; Lee, M; Martone, JF; Minckler, DS, 1991) |
| "Clonidine hydrochloride, apraclonidine hydrochloride, and brimonidine tartrate constitute the three topical alpha agonists that are used in the treatment of elevated intraocular pressure." | 4.80 | Selectivity of site of action and systemic effects of topical alpha agonists. ( Burnstein, Y; Robin, AL, 1998) |
| "To determine the incidence of intraocular pressure (IOP) rise of varying degrees after laser peripheral iridotomy (LPI) in patients with and without glaucoma treated perioperatively with pilocarpine and apraclonidine." | 3.70 | The rarity of clinically significant rise in intraocular pressure after laser peripheral iridotomy with apraclonidine. ( Gangnon, R; Heatley, GA; Kaufman, PL; Lewis, R; Perkins, TW, 1998) |
| "Intraocular pressure (IOP) measurements were carried out before and 1, 2 and 3 h after a single drop of apraclonidine." | 3.69 | Efficacy of apraclonidine ophthalmic solution (Iopidine) in presumed silicon oil-induced glaucoma and primary open-angle glaucoma. ( Busche, S; Gramer, E; Kampik, A; Parsons, D, 1995) |
| "0% apraclonidine in preventing intraocular pressure (IOP) spike after argon laser trabeculoplasty (ALT) in patients on chronic apraclonidine therapy compared with patients not on chronic apraclonidine use." | 3.69 | Chronic use of apraclonidine decreases its moderation of post-laser intraocular pressure spikes. ( Birt, CM; Chung, HS; Hakimzadeh, R; Juzych, MS; Kim, C; Lee, D; Levin, DS; Shin, DH, 1997) |
| "The intraocular pressures were measured at regular intervals during the 6-months follow-up period." | 2.80 | Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty. ( Anctil, JL; Champagne, S; Des Marchais, B; Goyette, A; Lajoie, C, 2015) |
| " 54 patients with bilateral primary open angle glaucoma and comparable IOP were assigned to three study groups: group 1 received the drug combination of pilocarpine 1% and clonidine 0." | 2.70 | A prospective, long-term, randomized study of the efficacy and safety of the drug combination pilocarpine 1% with clonidine 0.06% or clonidine 0.125% versus timolol 0.25%. ( Agarwal, H; Rajashekhar, YL; Sihota, R; Venkatesh, P, 2002) |
| "Apraclonidine 1." | 2.69 | Reversal of intraocular pressure increases with 0.5% apraclonidine after dilated fundus examination in patients with chronic open-angle glaucoma. ( Chang, FW; Kolin, T; Nishimoto, JH; Tang, IH, 1999) |
| "5% timolol maleate twice daily for at least 4 weeks and who had 8 AM IOPs of at least 22 mm Hg and no greater than 30 mm Hg 12 hours after dosing were eligible for the study." | 2.68 | The efficacy of apraclonidine as an adjunct to timolol therapy. Apraclonidine Adjunctive Therapy Study Group. ( Lehmann, RP; Ritch, R; Shin, DH; Shrader, CE; Stewart, WC; van Buskirk, EM, 1995) |
| "5% timolol 8 hours after dosing on days 1, 30, and 90; and a significant difference (P < ." | 2.68 | A 90-day study of the efficacy and side effects of 0.25% and 0.5% apraclonidine vs 0.5% timolol. Apraclonidine Primary Therapy Study Group. ( Horwitz, B; Kottler, M; Laibovitz, R; Ritch, R; Stewart, RH; Stewart, WC, 1996) |
| "The single dose response of open angle glaucoma eyes to pilocarpine 1%, clonidine 0." | 2.68 | A comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%. ( Agarwal, HC; Rajashekar, YL; Sihota, R, 1996) |
| "Clonidine ORs were used by 15 patients with glaucoma for 12 days." | 2.67 | The ophthalmic rod--a new drug-delivery system II. ( Alani, SD; Hammerstein, W, 1990) |
| "Clonidine did not cause allergic reaction in patients with proven allergy to apraclonidine, indicating that there is no cross-reactivity with apraclonidine." | 1.31 | Clonidine provides an allergy-free alternative in glaucoma patients with proven allergy to apraclonidine. ( Geyer, O; Lazar, M; Neudorfer, M; Pianka, P; Schmidt, KG, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (8.16) | 18.7374 |
| 1990's | 33 (67.35) | 18.2507 |
| 2000's | 8 (16.33) | 29.6817 |
| 2010's | 3 (6.12) | 24.3611 |
| 2020's | 1 (2.04) | 2.80 |
| Authors | Studies |
|---|---|
| Thrane, VR | 1 |
| Thrane, AS | 1 |
| Bergo, C | 1 |
| Halvorsen, H | 1 |
| Krohn, J | 1 |
| Champagne, S | 1 |
| Anctil, JL | 1 |
| Goyette, A | 1 |
| Lajoie, C | 1 |
| Des Marchais, B | 1 |
| Oatts, JT | 1 |
| Wang, X | 1 |
| Loewen, NA | 1 |
| Zhang, L | 1 |
| Weizer, JS | 1 |
| Musch, DC | 1 |
| Sebastiani, A | 2 |
| Parmeggiani, F | 1 |
| Costagliola, C | 1 |
| Ciancaglini, M | 1 |
| D'Oronzo, E | 1 |
| Mastropasqua, L | 1 |
| Sihota, R | 2 |
| Rajashekhar, YL | 1 |
| Venkatesh, P | 1 |
| Agarwal, H | 1 |
| Kotecha, A | 1 |
| Elsheikh, A | 1 |
| Roberts, CR | 1 |
| Zhu, H | 1 |
| Garway-Heath, DF | 1 |
| Lütjen-Drecoll, E | 1 |
| Kruse, FE | 1 |
| Meredith, SP | 1 |
| Swift, L | 1 |
| Eke, T | 1 |
| Broadway, DC | 1 |
| Petursson, G | 1 |
| Cole, R | 1 |
| Hanna, C | 1 |
| Robin, AL | 6 |
| Ritch, R | 4 |
| Shin, DH | 6 |
| Smythe, B | 2 |
| Mundorf, T | 2 |
| Lehmann, RP | 3 |
| Gramer, E | 2 |
| Busche, S | 1 |
| Kampik, A | 1 |
| Parsons, D | 1 |
| Stewart, WC | 4 |
| Shrader, CE | 1 |
| van Buskirk, EM | 1 |
| Hong, C | 1 |
| Song, KY | 1 |
| Dapling, RB | 1 |
| Cunliffe, IA | 1 |
| Longstaff, S | 1 |
| Muthusamy, P | 1 |
| Alimgil, ML | 1 |
| Erda, S | 1 |
| Benian, O | 1 |
| Nagasubramanian, S | 1 |
| Hitchings, RA | 1 |
| Demailly, P | 1 |
| Chuniaud, M | 1 |
| Pannarale, MR | 1 |
| Pecori-Giraldi, J | 1 |
| Stodtmeister, R | 2 |
| Parsons, DG | 1 |
| Laibovitz, R | 1 |
| Horwitz, B | 1 |
| Stewart, RH | 1 |
| Kottler, M | 1 |
| Shin, D | 1 |
| Agarwal, HC | 1 |
| Rajashekar, YL | 1 |
| Drake, MV | 1 |
| Chung, HS | 2 |
| Birt, CM | 2 |
| Kim, C | 3 |
| Lee, D | 1 |
| Levin, DS | 1 |
| Hakimzadeh, R | 1 |
| Juzych, MS | 2 |
| Yüksel, N | 1 |
| Elibol, O | 1 |
| Caglar, Y | 1 |
| Alçelik, T | 1 |
| Garrison, PM | 1 |
| Lamberti, G | 1 |
| Pignalosa, B | 1 |
| Fusco, R | 1 |
| Pignalosa, G | 1 |
| Di Govanni, A | 1 |
| Lewis, R | 1 |
| Perkins, TW | 1 |
| Gangnon, R | 1 |
| Kaufman, PL | 1 |
| Heatley, GA | 1 |
| Burnstein, Y | 1 |
| Glover, BK | 2 |
| Cha, SC | 1 |
| Kim, YY | 1 |
| Nguyen, KD | 1 |
| Ren, J | 1 |
| Hughes, BA | 1 |
| Nishimoto, JH | 1 |
| Chang, FW | 1 |
| Tang, IH | 1 |
| Kolin, T | 1 |
| Barnes, SD | 1 |
| Campagna, JA | 1 |
| Dirks, MS | 1 |
| Doe, EA | 1 |
| Konstas, AG | 1 |
| Maltezos, A | 1 |
| Mantziris, DA | 1 |
| Sine, CS | 1 |
| Geyer, O | 1 |
| Schmidt, KG | 1 |
| Pianka, P | 1 |
| Neudorfer, M | 1 |
| Lazar, M | 1 |
| Kuba, GB | 1 |
| Austermann, P | 1 |
| Chen, TC | 1 |
| Ang, RT | 1 |
| Grosskreutz, CL | 1 |
| Pasquale, LR | 1 |
| Fan, JT | 1 |
| Holmwood, PC | 1 |
| Chase, RD | 1 |
| Krupin, T | 1 |
| Rosenberg, LF | 1 |
| Ruderman, JM | 1 |
| Tallman, BA | 1 |
| Brodstein, DE | 1 |
| Chopra, H | 1 |
| Goldenfeld, M | 1 |
| Yaldo, MK | 1 |
| Parrow, KA | 1 |
| Lee, SH | 1 |
| Lee, SY | 1 |
| Hill, RA | 1 |
| Minckler, DS | 1 |
| Lee, M | 1 |
| Heuer, DK | 1 |
| Baerveldt, G | 1 |
| Martone, JF | 1 |
| Gharagozloo, NZ | 1 |
| Brubaker, RF | 1 |
| Nesher, R | 1 |
| Kolker, AE | 1 |
| Wilkerson, M | 1 |
| Lewis, RA | 1 |
| Shields, MB | 1 |
| Fernandez-Bahamonde, JL | 1 |
| Alcaraz-Michelli, V | 1 |
| Alani, SD | 1 |
| Hammerstein, W | 1 |
| Dandona, L | 1 |
| Morrison, JC | 1 |
| Quigley, HA | 1 |
| Marquardt, R | 1 |
| Pillunat, LE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Central Corneal Thickness and 24-hour Fluctuation of Intraocular Pressure[NCT00941525] | Phase 4 | 174 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
| Short-term Intraocular Pressure Control After YAG Iridotomy - Comparison Between Brimonidine 0.1% vs. 0.2%[NCT01417858] | 50 participants (Anticipated) | Interventional | 2010-11-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for clonidine and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty.
Topics: Adrenergic alpha-2 Receptor Agonists; Antihypertensive Agents; Brimonidine Tartrate; Clonidine; Conj | 2017 |
[Primary open angle glaucoma. Morphological bases for the understanding of the pathogenesis and effects of antiglaucomatic substances].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Age Factors; Aqueous Humor; Carbonic Anhydra | 2007 |
Questions concerning the role of apraclonidine in the management of glaucoma.
Topics: Adrenergic alpha-Agonists; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hyp | 1995 |
New medical therapies for glaucoma.
Topics: Adrenergic alpha-Agonists; Carbonic Anhydrase Inhibitors; Clonidine; Glaucoma, Open-Angle; Humans; I | 1996 |
Beta-blocker-induced complications and the patient with glaucoma. Newer treatments to help reduce systemic adverse events.
Topics: Adrenergic beta-Antagonists; Brimonidine Tartrate; Cardiovascular System; Central Nervous System; Cl | 1998 |
Selectivity of site of action and systemic effects of topical alpha agonists.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Clonidine; Glauco | 1998 |
32 trials available for clonidine and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Dicl | 2020 |
Influence on intraocular pressure of anti-inflammatory treatments after selective laser trabeculoplasty.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Combined Modalit | 2015 |
Effect of alpha-2-agonist premedication on intraocular pressure after selective laser trabeculoplasty.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Brimonidine Tartrate; Clonidine; Female; Glaucoma, Open- | 2015 |
Effects of acute topical administration of clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2% on visual field parameters and ocular perfusion pressure in patients with primary open-angle glaucoma.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aged; Blood Pressure; Brimonidine Tartrate; Clon | 2002 |
A prospective, long-term, randomized study of the efficacy and safety of the drug combination pilocarpine 1% with clonidine 0.06% or clonidine 0.125% versus timolol 0.25%.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Drug Administration Schedule; Dru | 2002 |
Treatment of glaucoma using minidrops of clonidine.
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Female; Glaucoma, Open-Angle; Humans; Male; Middle | 1984 |
Short-term efficacy of apraclonidine hydrochloride added to maximum-tolerated medical therapy for glaucoma. Apraclonidine Maximum-Tolerated Medical Therapy Study Group.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anh | 1995 |
The efficacy of apraclonidine as an adjunct to timolol therapy. Apraclonidine Adjunctive Therapy Study Group.
Topics: Adrenergic alpha-Agonists; Chemotherapy, Adjuvant; Clonidine; Double-Blind Method; Drug Administrati | 1995 |
Influence of apraclonidine and pilocarpine alone and in combination on post laser trabeculoplasty pressure rise.
Topics: Adrenergic beta-Agonists; Aged; Aged, 80 and over; Blood Pressure; Clonidine; Glaucoma, Open-Angle; | 1994 |
[The additive effect of dipivefrin in patients with wide angle glaucoma treated with long-term beta-blocker therapy in comparison with clonidine].
Topics: Clonidine; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Hum | 1994 |
Comparison of apraclonidine and timolol in chronic open-angle glaucoma. A three-month study.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Clonidine; Double-Blind Method; Drug Administration | 1993 |
A 90-day study of the efficacy and side effects of 0.25% and 0.5% apraclonidine vs 0.5% timolol. Apraclonidine Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Double-B | 1996 |
Topical apraclonidine hydrochloride in eyes with poorly controlled glaucoma. The Apraclonidine Maximum Tolerated Medical Therapy Study Group.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Clonidine; Doubl | 1995 |
A comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Blood Pressu | 1996 |
Short-term effect of apraclonidine on intraocular pressure in glaucoma patients receiving timolol and pilocarpine.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Clonidine; Dr | 1997 |
Short-term clinical trial evaluating the efficacy of the combination of apraclonidine 0.5% solution and betaxolol 0.25% suspension.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Chronic | 1997 |
Long-term brimonidine therapy in glaucoma patients with apraclonidine allergy.
Topics: Adrenergic alpha-Agonists; Aged; Brimonidine Tartrate; Chronic Disease; Clonidine; Drug Hypersensiti | 1999 |
Efficacy of apraclonidine 1% versus pilocarpine 4% for prophylaxis of intraocular pressure spike after argon laser trabeculoplasty.
Topics: Aged; Clonidine; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Laser Therap | 1999 |
Reversal of intraocular pressure increases with 0.5% apraclonidine after dilated fundus examination in patients with chronic open-angle glaucoma.
Topics: Adrenergic alpha-Agonists; Aged; Aged, 80 and over; Chronic Disease; Clonidine; Double-Blind Method; | 1999 |
Control of intraocular pressure elevations after argon laser trabeculoplasty: comparison of brimonidine 0.2% to apraclonidine 1.0%.
Topics: Adrenergic alpha-Agonists; Aged; Brimonidine Tartrate; Clonidine; Double-Blind Method; Female; Glauc | 1999 |
The comparative ocular hypotensive effect of apraclonidine with timolol maleate in exfoliation versus primary open-angle glaucoma patients.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Circadian Rhythm; Clonidine; Drug Ther | 1999 |
[Reduction of ocular pulse amplitude by apraclonidine--prospective double-blind, randomized clinical trial with 10 subjects].
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adult; Clonidine; Double-Blind Method; Female; G | 2001 |
Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anterior Eye Segment; Blood Pressure; Brimonidine Tartrate; Clonidi | 2001 |
Apraclonidine and argon laser trabeculoplasty.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Clonidine; Glaucoma, Open-Angle; Humans; Intraoc | 1992 |
Additive effect of 1% apraclonidine hydrochloride to nonselective beta-blockers.
Topics: Adrenergic alpha-Agonists; Clonidine; Double-Blind Method; Drug Synergism; Female; Glaucoma, Open-An | 1991 |
Apraclonidine prophylaxis for postcycloplegic intraocular pressure spikes.
Topics: Adrenergic alpha-Agonists; Clonidine; Double-Blind Method; Glaucoma, Open-Angle; Humans; Incidence; | 1991 |
Effect of apraclonidine in long-term timolol users.
Topics: Adrenergic alpha-Agonists; Aged; Aqueous Humor; Clonidine; Double-Blind Method; Drug Administration | 1991 |
Follicular conjunctivitis associated with apraclonidine.
Topics: Adult; Clonidine; Conjunctivitis; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Timolol | 1991 |
The combined use of apraclonidine and pilocarpine during laser iridotomy in a Hispanic population.
Topics: Aged; Clonidine; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Gl | 1990 |
The ophthalmic rod--a new drug-delivery system II.
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Clonidine; Conjunctiva; Female; Fluorescei | 1990 |
"Outlier" intraocular pressure readings: valid or invalid for statistical analysis?
Topics: Analysis of Variance; Clinical Trials as Topic; Clonidine; Data Interpretation, Statistical; Double- | 1989 |
[Ocular hemodynamics following local administration of clonidine].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Eye; Female; Glaucoma, Open-Angle; | 1988 |
11 other studies available for clonidine and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Corneal thickness- and age-related biomechanical properties of the cornea measured with the ocular response analyzer.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Aging; Biomechanical Phenomena; Clonidine | 2006 |
The acute morphologic changes that occur at the optic nerve head induced by medical reduction of intraocular pressure.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Aged; Aged, | 2007 |
Efficacy of apraclonidine ophthalmic solution (Iopidine) in presumed silicon oil-induced glaucoma and primary open-angle glaucoma.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Clonidine; Drug Tolerance; Fe | 1995 |
Effect of apraclonidine hydrochloride on the attack of Posner-Schlossman syndrome.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Female; Glaucoma, Open-Angle; Hemodyn | 1993 |
Apraclonidine in the management of glaucomatocyclitic crisis.
Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Female; Glaucoma, Open-Angle; Humans; Intraocular Press | 1994 |
Chronic use of apraclonidine decreases its moderation of post-laser intraocular pressure spikes.
Topics: Adrenergic alpha-Agonists; Aged; Clonidine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressu | 1997 |
[New drugs in glaucoma therapy].
Topics: Adrenergic alpha-Agonists; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibit | 1998 |
The rarity of clinically significant rise in intraocular pressure after laser peripheral iridotomy with apraclonidine.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Chemotherapy, Adjuvant; Clonidine; Female | 1998 |
Clonidine provides an allergy-free alternative in glaucoma patients with proven allergy to apraclonidine.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aged, 80 and over; Clonidine; Conjunctivitis, Al | 2000 |
Failure of apraclonidine to prevent delayed IOP elevation after Nd:YAG laser posterior capsulotomy.
Topics: Adrenergic alpha-Agonists; Aged; Clonidine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lase | 1990 |
The role of apraclonidine hydrochloride in laser therapy for glaucoma.
Topics: Acetazolamide; Adult; Aged; Animals; Clonidine; Epinephrine; Female; Glaucoma, Open-Angle; Humans; I | 1989 |