clonidine has been researched along with Fibromyalgia in 2 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Insulin induced hypoglycemia (< 3 mmol/l) and clonidine induced depression of noradrenergic tone were used to assess the acute effects of cortisol, human growth hormone (hGH), and norepinephrine (NE)." | 3.69 | Somatomedin C (insulin-like growth factor 1) levels decrease during acute changes of stress related hormones. Relevance for fibromyalgia. ( Baraldo, M; Bartoli, E; Ferraccioli, G; Furlanut, M; Guerra, P; Rizzi, V; Salaffi, F, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferraccioli, G | 1 |
| Guerra, P | 1 |
| Rizzi, V | 1 |
| Baraldo, M | 1 |
| Salaffi, F | 1 |
| Furlanut, M | 1 |
| Bartoli, E | 1 |
| Bennett, RM | 1 |
| Cook, DM | 1 |
| Clark, SR | 1 |
| Burckhardt, CS | 1 |
| Campbell, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Safety and Efficacy of MK-0677 25 mg in the Treatment of Primary Fibromyalgia[NCT00116129] | Phase 2 | 64 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for clonidine and Fibromyalgia
| Article | Year |
|---|---|
Somatomedin C (insulin-like growth factor 1) levels decrease during acute changes of stress related hormones. Relevance for fibromyalgia.
Topics: Clonidine; Female; Fibromyalgia; Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Insulin; Insu | 1994 |
Hypothalamic-pituitary-insulin-like growth factor-I axis dysfunction in patients with fibromyalgia.
Topics: Adult; Clonidine; Dopamine Agents; Female; Fibromyalgia; Humans; Hypothalamo-Hypophyseal System; Ins | 1997 |