clonidine has been researched along with Fatigue Syndrome, Chronic in 5 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Specifically, we assessed clonidine dosage in relation to a) plasma concentration levels, b) orthostatic cardiovascular responses, and c) possible adverse effects." | 2.77 | Clonidine in the treatment of adolescent chronic fatigue syndrome: a pilot study for the NorCAPITAL trial. ( Andersen, AM; Fagermoen, E; Saul, JP; Sulheim, D; Thaulow, E; Vethe, NT; Winger, A; Wyller, VB, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sulheim, D | 4 |
| Fagermoen, E | 4 |
| Winger, A | 4 |
| Andersen, AM | 3 |
| Godang, K | 2 |
| Müller, F | 1 |
| Rowe, PC | 2 |
| Saul, JP | 4 |
| Skovlund, E | 2 |
| Øie, MG | 1 |
| Wyller, VB | 4 |
| Gjerstad, J | 2 |
| Hall, KT | 1 |
| Kossowsky, J | 1 |
| Oberlander, TF | 1 |
| Kaptchuk, TJ | 1 |
| Mukamal, KJ | 1 |
| Vethe, NT | 1 |
| Thaulow, E | 1 |
| Morriss, RK | 1 |
| Robson, MJ | 1 |
| Deakin, JF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Norwegian Study of Chronic Fatigue Syndrome in Adolescents: Pathophysiology and Intervention Trial[NCT01040429] | Phase 2 | 120 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| Pilot Study for the NorCAPITAL Trial[NCT01507701] | 5 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for clonidine and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Disease mechanisms and clonidine treatment in adolescent chronic fatigue syndrome: a combined cross-sectional and randomized clinical trial.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; C-Reactive Protein; Clonidine; Creatinine; Cross-S | 2014 |
Effects of low-dose clonidine on cardiovascular and autonomic variables in adolescents with chronic fatigue: a randomized controlled trial.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Clonidine; Creatinine; Double-Blind Method; Epinep | 2015 |
Genetic variation in catechol-O-methyltransferase modifies effects of clonidine treatment in chronic fatigue syndrome.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Catechol O-Methyltransferase; Child; Clonidine; Do | 2016 |
Clonidine in the treatment of adolescent chronic fatigue syndrome: a pilot study for the NorCAPITAL trial.
Topics: Adolescent; Clonidine; Fatigue Syndrome, Chronic; Female; Hemodynamics; Humans; Male; Norway; Pilot | 2012 |
Clonidine in the treatment of adolescent chronic fatigue syndrome: a pilot study for the NorCAPITAL trial.
Topics: Adolescent; Clonidine; Fatigue Syndrome, Chronic; Female; Hemodynamics; Humans; Male; Norway; Pilot | 2012 |
Clonidine in the treatment of adolescent chronic fatigue syndrome: a pilot study for the NorCAPITAL trial.
Topics: Adolescent; Clonidine; Fatigue Syndrome, Chronic; Female; Hemodynamics; Humans; Male; Norway; Pilot | 2012 |
Clonidine in the treatment of adolescent chronic fatigue syndrome: a pilot study for the NorCAPITAL trial.
Topics: Adolescent; Clonidine; Fatigue Syndrome, Chronic; Female; Hemodynamics; Humans; Male; Norway; Pilot | 2012 |
Neuropsychological performance and noradrenaline function in chronic fatigue syndrome under conditions of high arousal.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Analysis of Variance; Area Under Curve; Arousal; Clonid | 2002 |