clonidine has been researched along with Epileptiform Neuralgia in 11 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a double-blind study the efficacy and tolerability of tizanidine was compared with those of carbamazepine in the management of trigeminal neuralgia." | 9.06 | Tizanidine in the management of trigeminal neuralgia. ( Lataste, X; Lyberg, T; Vilming, ST, 1986) |
| "In the present study we report two typical cases of trigeminal neuralgia in whom all conventional drug treatments were attempted without success, and in whom low doses of pimozide, a dopaminergic blocking agent, provoked a definite and sustained improvement." | 7.67 | Definite and sustained improvement with pimozide of two patients with severe trigeminal neuralgia. Some neurochemical, neurophysiological and neuroendocrinological findings. ( Amat, J; Arocha, L; Cabrera, A; Gómez, F; Jiménez, V; Lechin, AE; Lechin, F; Lechin, ME; van der Dijs, B, 1988) |
| "The limited efficacy of TZD in the treatment of trigeminal neuralgia may be related to the fact that it has no effect on neuronal responses to low-threshold mechanoceptive stimuli, suggesting that low-threshold mechanoceptive neurons play an important role in the pathogenesis of trigeminal neuralgia." | 6.67 | A clinical and experimental investigation of the effects of tizanidine in trigeminal neuralgia. ( Aumentado, D; Fromm, GH; Terrence, CF, 1993) |
| "In a double-blind study the efficacy and tolerability of tizanidine was compared with those of carbamazepine in the management of trigeminal neuralgia." | 5.06 | Tizanidine in the management of trigeminal neuralgia. ( Lataste, X; Lyberg, T; Vilming, ST, 1986) |
| "There is low-quality evidence that the effect of tizanidine is not significantly different than that of carbamazepine in treating trigeminal neuralgia." | 4.89 | Non-antiepileptic drugs for trigeminal neuralgia. ( Chen, N; He, L; Yang, M; Zakrzewska, JM; Zhang, J; Zhou, M, 2013) |
| "In the present study we report two typical cases of trigeminal neuralgia in whom all conventional drug treatments were attempted without success, and in whom low doses of pimozide, a dopaminergic blocking agent, provoked a definite and sustained improvement." | 3.67 | Definite and sustained improvement with pimozide of two patients with severe trigeminal neuralgia. Some neurochemical, neurophysiological and neuroendocrinological findings. ( Amat, J; Arocha, L; Cabrera, A; Gómez, F; Jiménez, V; Lechin, AE; Lechin, F; Lechin, ME; van der Dijs, B, 1988) |
| "The limited efficacy of TZD in the treatment of trigeminal neuralgia may be related to the fact that it has no effect on neuronal responses to low-threshold mechanoceptive stimuli, suggesting that low-threshold mechanoceptive neurons play an important role in the pathogenesis of trigeminal neuralgia." | 2.67 | A clinical and experimental investigation of the effects of tizanidine in trigeminal neuralgia. ( Aumentado, D; Fromm, GH; Terrence, CF, 1993) |
| "Tizanidine was investigated in two trials." | 2.43 | Non-antiepileptic drugs for trigeminal neuralgia. ( He, L; Wu, B; Zhou, M, 2006) |
| "Among the more common symptoms is spasticity." | 2.41 | Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis. ( Schapiro, RT, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Jacques, N | 1 |
| Karoutsos, S | 1 |
| Marais, L | 1 |
| Nathan-Denizot, N | 1 |
| Escrivá, E | 1 |
| Martínez-Costa, L | 1 |
| Zhang, J | 1 |
| Yang, M | 2 |
| Zhou, M | 3 |
| He, L | 3 |
| Chen, N | 2 |
| Zakrzewska, JM | 2 |
| Takeda, M | 1 |
| Ikeda, M | 1 |
| Tanimoto, T | 1 |
| Lipski, J | 1 |
| Matsumoto, S | 1 |
| Naja, MZ | 1 |
| Al-Tannir, M | 1 |
| Naja, H | 1 |
| Ziade, MF | 1 |
| Zeidan, A | 1 |
| Wu, B | 1 |
| Fromm, GH | 1 |
| Aumentado, D | 1 |
| Terrence, CF | 1 |
| Schapiro, RT | 1 |
| Lechin, F | 1 |
| van der Dijs, B | 1 |
| Amat, J | 1 |
| Lechin, AE | 1 |
| Cabrera, A | 1 |
| Lechin, ME | 1 |
| Gómez, F | 1 |
| Arocha, L | 1 |
| Jiménez, V | 1 |
| Vilming, ST | 1 |
| Lyberg, T | 1 |
| Lataste, X | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Analgesic Effect Evaluation of Ultrasound Guided Maxillary Nerve Block in Trigeminal Neuralgia[NCT06129071] | 10 participants (Anticipated) | Interventional | 2023-12-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for clonidine and Epileptiform Neuralgia
| Article | Year |
|---|---|
Quality of life after trigeminal nerve block in refractory trigeminal neuralgia: A retrospective cohort study and literature review.
Topics: Clonidine; Humans; Levobupivacaine; Observational Studies as Topic; Quality of Life; Retrospective S | 2022 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Anticonvulsants; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans | 2013 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Analgesics; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propo | 2011 |
Non-antiepileptic drugs for trigeminal neuralgia.
Topics: Amitriptyline; Baclofen; Carbamazepine; Clomipramine; Clonidine; Humans; Pimozide; Propoxycaine; Ran | 2006 |
Management of spasticity, pain, and paroxysmal phenomena in multiple sclerosis.
Topics: Acetates; Amines; Autoimmune Diseases; Baclofen; Benzodiazepines; Botulinum Toxins, Type A; Cannabin | 2001 |
2 trials available for clonidine and Epileptiform Neuralgia
| Article | Year |
|---|---|
A clinical and experimental investigation of the effects of tizanidine in trigeminal neuralgia.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Animals; Cats; Clonidine; Double-Blind Method; Drug Resi | 1993 |
Tizanidine in the management of trigeminal neuralgia.
Topics: Aged; Analgesics; Carbamazepine; Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; M | 1986 |
4 other studies available for clonidine and Epileptiform Neuralgia
| Article | Year |
|---|---|
[Incomplete Horner's syndrome as a presenting sign of fourth ventricle ependymoma].
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Blepharoptosis; Cerebral Ventricle Neoplasms; Clonidine | 2013 |
Changes of the excitability of rat trigeminal root ganglion neurons evoked by alpha(2)-adrenoreceptors.
Topics: Action Potentials; Adrenergic alpha-Agonists; Animals; Animals, Newborn; Brimonidine Tartrate; Cell | 2002 |
Repeated nerve blocks with clonidine, fentanyl and bupivacaine for trigeminal neuralgia.
Topics: Anesthetics; Bupivacaine; Chronic Disease; Clonidine; Electric Stimulation; Fentanyl; Humans; Nerve | 2006 |
Definite and sustained improvement with pimozide of two patients with severe trigeminal neuralgia. Some neurochemical, neurophysiological and neuroendocrinological findings.
Topics: Aged; Clonidine; Colon; Depression; Female; Gastrointestinal Motility; Humans; Male; Middle Aged; No | 1988 |