clonidine has been researched along with Endotoxemia in 3 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study evaluated the effect of the adrenergic alpha 2 agonist clonidine on microvascular permeability and leukocyte adhesion during endotoxemia." | 7.81 | Time-dependent effect of clonidine on microvascular permeability during endotoxemia. ( Brenner, T; Hernekamp, JF; Hofer, S; Philipsenburg, C; Schmidt, K; Zivkovic, AR, 2015) |
| "To study the effect of clonidine pre-treatment on hemorrhagic shock (H/S)-induced endotoxemia and oxidative stress (OS) in three vital organs of the rat." | 7.78 | Clonidine pre-treatment prevents hemorrhagic shock-induced endotoxemia and oxidative stress in the gut, liver, and lungs of the rat. ( Filos, KS; Fligou, F; Georgiou, C; Panteli, ES; Papamichail, C; Papapostolou, I; Spiliopoulou, I; Zervoudakis, G, 2012) |
| " This study evaluated the effect of the adrenergic alpha 2 agonist clonidine on microvascular permeability and leukocyte adhesion during endotoxemia." | 3.81 | Time-dependent effect of clonidine on microvascular permeability during endotoxemia. ( Brenner, T; Hernekamp, JF; Hofer, S; Philipsenburg, C; Schmidt, K; Zivkovic, AR, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schmidt, K | 1 |
| Hernekamp, JF | 1 |
| Philipsenburg, C | 1 |
| Zivkovic, AR | 1 |
| Brenner, T | 1 |
| Hofer, S | 1 |
| Quintin, L | 1 |
| Filos, KS | 1 |
| Panteli, ES | 1 |
| Fligou, F | 1 |
| Papamichail, C | 1 |
| Papapostolou, I | 1 |
| Zervoudakis, G | 1 |
| Spiliopoulou, I | 1 |
| Georgiou, C | 1 |
3 other studies available for clonidine and Endotoxemia
| Article | Year |
|---|---|
Time-dependent effect of clonidine on microvascular permeability during endotoxemia.
Topics: Animals; Capillary Permeability; Cell Adhesion; Clonidine; Endothelial Cells; Endotoxemia; Inflammat | 2015 |
Reduced experimental vascular leakage following alpha-2 agonists: Any clinical relevance?
Topics: Animals; Capillary Permeability; Clonidine; Endotoxemia; Male; Microcirculation | 2016 |
Clonidine pre-treatment prevents hemorrhagic shock-induced endotoxemia and oxidative stress in the gut, liver, and lungs of the rat.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Abdominal; Bacterial Translocation; Clonidine; Endotoxemi | 2012 |