Page last updated: 2024-10-25

clonidine and Encephalopathy, Traumatic

clonidine has been researched along with Encephalopathy, Traumatic in 4 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
" We hypothesized that early and unselective beta-blockade with propranolol alone or in combination with the alfa2-agonist clonidine would decrease brain edema, blood-brain barrier permeability, and glycocalyx disruption at 24 hours after trauma."7.88Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat. ( Bentzer, P; Genét, GF; Hansen, MB; Johansson, PI; Ostrowski, SR, 2018)
" The study aimed to determine the risk of TBI in TS patients, the effects associated with concurrent psychiatric disorders (attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), or depressive disorder), and the effects of medication treatment (antipsychotics, antidepressants, or clonidine) on the risk of TBI."3.91Tourette's syndrome is associated with an increased risk of traumatic brain injury: A nationwide population-based cohort study. ( Chen, SF; Hsu, CY; Shen, YC; Su, YC; Wang, LY, 2019)
" We hypothesized that early and unselective beta-blockade with propranolol alone or in combination with the alfa2-agonist clonidine would decrease brain edema, blood-brain barrier permeability, and glycocalyx disruption at 24 hours after trauma."3.88Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat. ( Bentzer, P; Genét, GF; Hansen, MB; Johansson, PI; Ostrowski, SR, 2018)
"Glycerol has been associated with membrane degradation and may support glycerol as a biomarker for vascular endothelial breakdown."2.90Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury. ( Eklund, A; Hägglund, L; Koskinen, LD; Olivecrona, M; Sundström, N, 2019)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Nordness, MF1
Maiga, AW1
Wilson, LD1
Koyama, T1
Rivera, EL1
Rakhit, S1
de Riesthal, M1
Motuzas, CL1
Cook, MR1
Gupta, DK1
Jackson, JC1
Williams Roberson, S1
Meurer, WJ1
Lewis, RJ1
Manley, GT1
Pandharipande, PP1
Patel, MB1
Genét, GF1
Bentzer, P1
Hansen, MB1
Ostrowski, SR1
Johansson, PI1
Chen, SF1
Su, YC1
Wang, LY1
Hsu, CY1
Shen, YC1
Koskinen, LD1
Sundström, N1
Hägglund, L1
Eklund, A1
Olivecrona, M1

Trials

2 trials available for clonidine and Encephalopathy, Traumatic

ArticleYear
Effect of propranolol and clonidine after severe traumatic brain injury: a pilot randomized clinical trial.
    Critical care (London, England), 2023, 06-09, Volume: 27, Issue:1

    Topics: Adrenergic Agents; Brain Injuries, Traumatic; Clonidine; Humans; Pilot Projects; Propranolol; Treatm

2023
Prostacyclin Affects the Relation Between Brain Interstitial Glycerol and Cerebrovascular Pressure Reactivity in Severe Traumatic Brain Injury.
    Neurocritical care, 2019, Volume: 31, Issue:3

    Topics: Adult; Antihypertensive Agents; Arterial Pressure; Blood Pressure; Brain; Brain Injuries, Traumatic;

2019

Other Studies

2 other studies available for clonidine and Encephalopathy, Traumatic

ArticleYear
Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat.
    The journal of trauma and acute care surgery, 2018, Volume: 84, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Blood-Brain Barrier; Bra

2018
Tourette's syndrome is associated with an increased risk of traumatic brain injury: A nationwide population-based cohort study.
    Parkinsonism & related disorders, 2019, Volume: 63

    Topics: Adolescent; Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hype

2019