clonidine has been researched along with Emesis, Postoperative in 39 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the effect of oral clonidine on postoperative vomiting (POV) in children undergoing strabismus surgery." | 9.10 | Oral clonidine premedication does not reduce postoperative vomiting in children undergoing strabismus surgery. ( Durmus, M; Ersoy, MO; Gedik, E; Gulhas, N; Togal, T; Turkoz, A, 2003) |
| " Our hypothesis is that coinduction with clonidine reduces the incidence of PONV in adult patients undergoing breast cancer surgery." | 9.10 | Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. ( Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Muhrbeck, O; Oddby-Muhrbeck, E, 2002) |
| "We evaluated the efficacy of clonidine given orally preoperatively for preventing postoperative vomiting (POV) in children undergoing propofol-nitrous oxide anaesthesia for strabismus surgery." | 9.09 | The efficacy of oral clonidine premedication in the prevention of postoperative vomiting in children following strabismus surgery. ( Fujii, Y; Handa, F, 2001) |
| "Clonidine appears a safe and beneficial drug with moderate to high-quality evidence supporting its use in pediatric anesthesia." | 9.01 | Clonidine in pediatric anesthesia: the new panacea or a drug still looking for an indication? ( Afshari, A, 2019) |
| "Intrathecal morphine (ITM) is a widely used technique for postcaesarean section analgesia but entails a high risk of postoperative nausea and vomiting (PONV)." | 5.30 | The impact of a transversus abdominis plane block including clonidine vs. intrathecal morphine on nausea and vomiting after caesarean section: A randomised controlled trial. ( Combescure, C; Dereu, D; Mathivon, S; Mercier, Y; Rehberg, B; Savoldelli, GL, 2019) |
| "In 139 patients anxiety, sedation and adverse effects were measured at 6 consecutive perioperative time points after administration of midazolam, clonidine or a placebo." | 5.14 | [Quality of premedication and patient satisfaction after premedication with midazolam, clonidine or placebo : Randomized double-blind study with age-adjusted dosage]. ( Ivleva-Sauerborn, A; Seifert, B; Spahn, DR; Zalunardo, MP, 2010) |
| " The addition of clonidine 2 microg/kg to bupivacaine provides a prolonged anesthetic action but may be associated with hypotension." | 5.12 | Clonidine 1 microg/kg is a safe and effective adjuvant to plain bupivacaine in spinal anesthesia in adolescents. ( Abdelaziz, AB; Chattaoui, O; Kaabachi, O; Kokki, H; Ouezini, R; Zarghouni, A, 2007) |
| "We evaluated the effect of oral clonidine on postoperative vomiting (POV) in children undergoing strabismus surgery." | 5.10 | Oral clonidine premedication does not reduce postoperative vomiting in children undergoing strabismus surgery. ( Durmus, M; Ersoy, MO; Gedik, E; Gulhas, N; Togal, T; Turkoz, A, 2003) |
| " In the postoperative period the incidence of postoperative nausea and vomiting (PONV) (ND: n = 8, HD: n = 2, midazolam: n = 6) and the use of pritramid were lower in the clonidine HD group (HD: 38." | 5.10 | [Comparison of premedication with clonidine and midazolam combined with TCI for orthopaedic shoulder surgery]. ( Dietrich, PJ; Grottke, O; Krause, TH; Müller, J; Wappler, F, 2003) |
| " Our hypothesis is that coinduction with clonidine reduces the incidence of PONV in adult patients undergoing breast cancer surgery." | 5.10 | Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. ( Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Muhrbeck, O; Oddby-Muhrbeck, E, 2002) |
| "We evaluated the efficacy of clonidine given orally preoperatively for preventing postoperative vomiting (POV) in children undergoing propofol-nitrous oxide anaesthesia for strabismus surgery." | 5.09 | The efficacy of oral clonidine premedication in the prevention of postoperative vomiting in children following strabismus surgery. ( Fujii, Y; Handa, F, 2001) |
| "Clonidine appears a safe and beneficial drug with moderate to high-quality evidence supporting its use in pediatric anesthesia." | 5.01 | Clonidine in pediatric anesthesia: the new panacea or a drug still looking for an indication? ( Afshari, A, 2019) |
| "Compared with control intervention, clonidine intervention was found to significantly reduce MAP and HR at pneumoperitoneum and intubation, propofol requirement, as well as postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy." | 4.95 | Effect of Clonidine on Hemodynamic Responses During Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis. ( Wang, Y; Zhang, J; Zhang, X; Zhang, Y, 2017) |
| " A continuous low dose IV midazolam infusion was added to his treatment regimen (as is instituted for recalcitrant postoperative nausea and vomiting) with benefit, but not total symptom resolution." | 3.73 | Use of intravenous midazolam and clonidine in cyclical vomiting syndrome: a case report. ( Cameron, DJ; Palmer, GM, 2005) |
| "The incidence of postoperative nausea in women was more than men (p=0." | 2.87 | Comparison of Ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after orthognathic surgeries: A triple blind randomized controlled trial. ( Eshghpour, M; Hashemipour, MS; Hosseini-Abrishami, M; Mianbandi, V; Samieirad, S; Shadkam, E; Sharifian-Attar, A, 2018) |
| "Clonidine has been shown to reduce intraoperative haemodynamic instability." | 2.84 | Role of Oral Clonidine Premedication on Intra-operative Haemodynamics and PONV in Laparoscopic Cholecystectomy. ( Banik, D; Haque, AK; Jahan, S; Masud, M; Saha, NC; Yeasmeen, S, 2017) |
| "Melatonin was effective for steal induction in 75% of children compared to 88% of children who had clonidine." | 2.78 | Steal induction in preschool children: is melatonin as good as clonidine? A prospective, randomized study. ( Almenrader, N; Haiberger, R; Passariello, M, 2013) |
| "Clonidine has the potential to significantly prolong the duration of caudal epidural anesthesia." | 2.76 | Effect of epidural clonidine on minimum local anesthetic concentration (ED50) of levobupivacaine for caudal block in children. ( Alberighi, OD; Disma, N; Frawley, G; Mameli, L; Montobbio, G; Pistorio, A; Tuo, P, 2011) |
| "Clonidine is an alpha(2) adrenoreceptor and imidazoline receptor agonist, which has analgesic, sedative, and minimum alveolar anesthetic concentration-sparing effects." | 2.74 | The analgesic effect of epidural clonidine after spinal surgery: a randomized placebo-controlled trial. ( Farmery, AD; Wilson-MacDonald, J, 2009) |
| "Spinal anesthesia with supplemental epidural clonidine in combination with incision site subcutaneous bupivacaine was evaluated both intra- and postoperatively and compared with spinal anesthesia alone for lower lumbar spine procedures." | 2.71 | The effect of spinal bupivacaine in combination with either epidural clonidine and/or 0.5% bupivacaine administered at the incision site on postoperative outcome in patients undergoing lumbar laminectomy. ( Abodeely, A; Fluder, EM; Jellish, WS; Shea, J, 2003) |
| "The efficiency of bilateral paravertebral blockade combined with general anaesthesia (active) vs." | 2.71 | General anaesthesia combined with bilateral paravertebral blockade (T5-6) vs. general anaesthesia for laparoscopic cholecystectomy: a prospective, randomized clinical trial. ( Lönnqvist, PA; Naja, MZ; Ziade, MF, 2004) |
| "The incidence of immediate postoperative pain (0-2 h), as assessed by repeated Objective Pain Scale (OPS) scores, was chosen as the primary end-point of the study." | 2.71 | Clonidine vs. midazolam as premedication in children undergoing adeno-tonsillectomy: a prospective, randomized, controlled clinical trial. ( Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Nordenberg, L; Oddby, E; Ruthström, E; Zetterqvist, H, 2004) |
| "To determine whether a low dose of spinal clonidine either alone or combined with sufentanil would provide effective analgesia following abdominal surgery, as a supplement to bupivacaine spinal anesthesia." | 2.69 | Low-dose intrathecal clonidine combined with sufentanil as analgesic drugs in abdominal gynecological surgery. ( Julião, MC; Lauretti, GR, 2000) |
| "Clonidine has antiemetic and analgesic properties and thus may be used as premedication to reduce postoperative vomiting and pain." | 2.61 | Safety and efficacy of clonidine on postoperative vomiting and pain in pediatric ophthalmic surgery: A systematic review and meta-analysis. ( Bai, CH; Chen, C; Chu, KC; Hsu, CW; Hsu, YP; Huang, CJ, 2019) |
| "Neostigmine and tramadol increase the probability for post-operative nausea or vomiting (PONV)." | 2.48 | Bayesian enhanced meta-analysis of post-operative analgesic efficacy of additives for caudal analgesia in children. ( Engelman, E; Marsala, C, 2012) |
| "There is considerable evidence that caudally administered clonidine in addition to local anesthetics provides extended duration of analgesia with a decreased incidence for analgesic rescue requirement and little adverse effects compared to caudal local anesthetics alone." | 2.47 | Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials. ( Poepping, DM; Pogatzki-Zahn, EM; Schnabel, A; Zahn, PK, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (48.72) | 29.6817 |
| 2010's | 20 (51.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sanchez Munoz, MC | 1 |
| De Kock, M | 1 |
| Forget, P | 1 |
| Zhang, Y | 1 |
| Zhang, X | 1 |
| Wang, Y | 1 |
| Zhang, J | 1 |
| Masud, M | 1 |
| Yeasmeen, S | 1 |
| Haque, AK | 1 |
| Jahan, S | 1 |
| Saha, NC | 1 |
| Banik, D | 1 |
| Samieirad, S | 1 |
| Sharifian-Attar, A | 1 |
| Eshghpour, M | 1 |
| Mianbandi, V | 1 |
| Shadkam, E | 1 |
| Hosseini-Abrishami, M | 1 |
| Hashemipour, MS | 1 |
| Afshari, A | 1 |
| Dereu, D | 1 |
| Savoldelli, GL | 1 |
| Mercier, Y | 1 |
| Combescure, C | 1 |
| Mathivon, S | 1 |
| Rehberg, B | 1 |
| Hsu, YP | 1 |
| Chu, KC | 1 |
| Bai, CH | 1 |
| Huang, CJ | 1 |
| Chen, C | 1 |
| Hsu, CW | 1 |
| Tietje, T | 1 |
| Davis, AB | 1 |
| Rivey, MP | 1 |
| Carvalho, FA | 1 |
| Tenório, SB | 1 |
| Shiohara, FT | 1 |
| Maia, LR | 1 |
| Mota, A | 1 |
| Vlok, R | 1 |
| Melhuish, TM | 1 |
| Chong, C | 1 |
| Ryan, T | 1 |
| White, LD | 1 |
| Farmery, AD | 1 |
| Wilson-MacDonald, J | 1 |
| Dahmani, S | 1 |
| Brasher, C | 1 |
| Stany, I | 1 |
| Golmard, J | 1 |
| Skhiri, A | 1 |
| Bruneau, B | 1 |
| Nivoche, Y | 1 |
| Constant, I | 1 |
| Murat, I | 1 |
| Zalunardo, MP | 1 |
| Ivleva-Sauerborn, A | 1 |
| Seifert, B | 1 |
| Spahn, DR | 1 |
| Taheri, A | 1 |
| Javadimanesh, MA | 1 |
| Ashraf, H | 1 |
| Disma, N | 1 |
| Frawley, G | 1 |
| Mameli, L | 1 |
| Pistorio, A | 1 |
| Alberighi, OD | 1 |
| Montobbio, G | 1 |
| Tuo, P | 1 |
| Schnabel, A | 1 |
| Poepping, DM | 1 |
| Pogatzki-Zahn, EM | 1 |
| Zahn, PK | 1 |
| Engelman, E | 2 |
| Marsala, C | 2 |
| Apostolos, K | 1 |
| Georgios, K | 1 |
| Omiros, C | 1 |
| Christos, T | 1 |
| Blaudszun, G | 1 |
| Lysakowski, C | 1 |
| Elia, N | 1 |
| Tramèr, MR | 1 |
| Almenrader, N | 1 |
| Haiberger, R | 1 |
| Passariello, M | 1 |
| Gulhas, N | 1 |
| Turkoz, A | 1 |
| Durmus, M | 1 |
| Togal, T | 1 |
| Gedik, E | 1 |
| Ersoy, MO | 1 |
| Gürses, E | 1 |
| Sungurtekin, H | 1 |
| Tomatir, E | 1 |
| Balci, C | 1 |
| Gönüllü, M | 1 |
| Jellish, WS | 1 |
| Abodeely, A | 1 |
| Fluder, EM | 1 |
| Shea, J | 1 |
| Grottke, O | 1 |
| Müller, J | 1 |
| Dietrich, PJ | 1 |
| Krause, TH | 1 |
| Wappler, F | 1 |
| Klamt, JG | 1 |
| Garcia, LV | 1 |
| Stocche, RM | 1 |
| Meinberg, AC | 1 |
| Joshi, W | 1 |
| Connelly, NR | 1 |
| Freeman, K | 1 |
| Reuben, SS | 1 |
| Naja, MZ | 1 |
| Ziade, MF | 1 |
| Lönnqvist, PA | 3 |
| Bergendahl, HT | 2 |
| Eksborg, S | 2 |
| Ruthström, E | 1 |
| Nordenberg, L | 1 |
| Zetterqvist, H | 1 |
| Oddby, E | 1 |
| Palmer, GM | 1 |
| Cameron, DJ | 1 |
| Dalsasso, M | 1 |
| Tresin, P | 1 |
| Innocente, F | 1 |
| Veronese, S | 1 |
| Ori, C | 1 |
| Zhao, H | 1 |
| Ishiyama, T | 1 |
| Oguchi, T | 1 |
| Kumazawa, T | 1 |
| Ball, AM | 1 |
| Smith, KM | 1 |
| Contreras-Dominguez, V | 1 |
| Carbonell-Bellolioa, P | 1 |
| Ojeda-Greciet, A | 1 |
| Sanzana, ES | 1 |
| Kaabachi, O | 1 |
| Zarghouni, A | 1 |
| Ouezini, R | 1 |
| Abdelaziz, AB | 1 |
| Chattaoui, O | 1 |
| Kokki, H | 1 |
| Frank, T | 1 |
| Thieme, V | 1 |
| Radow, L | 1 |
| Julião, MC | 1 |
| Lauretti, GR | 1 |
| Handa, F | 1 |
| Fujii, Y | 1 |
| Oddby-Muhrbeck, E | 1 |
| Muhrbeck, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clonidine for Tourniquet-related Pain in Children: A Pilot Study[NCT04564430] | Phase 4 | 20 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| Transversus Abdominis Plane (TAP) Block Versus Intrathecal Morphine for Caesarean Section - Randomised Controlled Trial[NCT01931215] | Phase 4 | 180 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Randomized, Controlled Trial of Post-operative Steroids and Pain Control After Tonsillectomy[NCT03995628] | Phase 2 | 150 participants (Anticipated) | Interventional | 2018-12-18 | Recruiting | ||
| Effects of Premedication by Midazolam on Preoperative Anxiety for Emergency Surgery[NCT02213302] | Phase 4 | 59 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| A Prospective Study Comparing Total Intravenous Anesthesia With Propofol and Remifentanil vs. Propofol and Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Undergoing Posterior Spinal Fusion and Instrumentation[NCT06096181] | Phase 2 | 120 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting | ||
| Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia With Isobaric Bupivacaine in Patients Undergoing Surgery to Treat Skin and Soft Tissue Tumors of the Lower Limbs[NCT04741880] | Phase 2/Phase 3 | 66 participants (Anticipated) | Interventional | 2021-06-17 | Recruiting | ||
| Guanfacine for PONV and Pain After Sinus Surgery[NCT02882854] | 84 participants (Actual) | Interventional | 2016-11-30 | Completed | |||
| A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain[NCT02289261] | Phase 4 | 40 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| Dexmedetomidine Comme Adjuvant à la rachianesthésie Lors de césariennes électives : Une étude Pilote[NCT05099055] | Phase 3 | 42 participants (Actual) | Interventional | 2022-03-15 | Completed | ||
| Effects of Clonidine and Midazolam Premedication on Bispectral Index and Recovery After Elective Surgery[NCT00638729] | 60 participants (Actual) | Interventional | 2005-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT02882854)
Timeframe: Time frame between arrival and discharge in PACU, approximately 90 minutes
| Intervention | minutes (Median) |
|---|---|
| Guanfacine | 128 |
| Placebo | 110 |
PONV assessed using nVRS at 24 hours postop when 0 is no nausea and 10 is worst nausea. (NCT02882854)
Timeframe: 24 hours post op
| Intervention | score on a scale (Median) |
|---|---|
| Guanfacine | 0.00 |
| Placebo | 0.00 |
Postoperative pain assessment using VAS at 24 hours postop when 0 is no pain and 10 is worst pain (NCT02882854)
Timeframe: 24 hours postop
| Intervention | score on a scale (Median) |
|---|---|
| Guanfacine | 3 |
| Placebo | 2 |
Total narcotic requirement in PACU tallied in morphine equivalents during PACU stay (NCT02882854)
Timeframe: Time frame between arrival and discharge in PACU, approximately 90 minutes
| Intervention | morphine equivalents (Median) |
|---|---|
| Guanfacine | 8.75 |
| Placebo | 7.50 |
Maximum postoperative pain assessment assessed in PACU at 15, 30 and 60 minutes after PACU arrival using VAS when 0 is no pain and 10 is worst pain (NCT02882854)
Timeframe: 15, 30, 60 minutes after arriving in PACU
| Intervention | Participants (Count of Participants) | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 15 minutes after PACU admission72482977 | 15 minutes after PACU admission72482978 | 30 minutes after PACU admission72482977 | 30 minutes after PACU admission72482978 | 60 minutes after PACU admission72482977 | 60 minutes after PACU admission72482978 | |||||||||||||
| Mild (Pain nVRS 1-5) | Moderate/Severe (Pain nVRS 6-10) | None (Pain nVRS 0) | ||||||||||||||||
| Guanfacine | 31 | |||||||||||||||||
| Placebo | 24 | |||||||||||||||||
| Guanfacine | 0 | |||||||||||||||||
| Placebo | 5 | |||||||||||||||||
| Guanfacine | 8 | |||||||||||||||||
| Placebo | 10 | |||||||||||||||||
| Guanfacine | 18 | |||||||||||||||||
| Placebo | 20 | |||||||||||||||||
| Guanfacine | 7 | |||||||||||||||||
| Placebo | 6 | |||||||||||||||||
| Guanfacine | 14 | |||||||||||||||||
| Placebo | 14 | |||||||||||||||||
| Guanfacine | 12 | |||||||||||||||||
| Placebo | 16 | |||||||||||||||||
| Guanfacine | 6 | |||||||||||||||||
| Placebo | 13 | |||||||||||||||||
| Guanfacine | 21 | |||||||||||||||||
| Placebo | 12 | |||||||||||||||||
11 reviews available for clonidine and Emesis, Postoperative
| Article | Year |
|---|---|
What is the place of clonidine in anesthesia? Systematic review and meta-analyses of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics; Anesthesia; Clonidine; Heart; Hemodynamics; Humans | 2017 |
Effect of Clonidine on Hemodynamic Responses During Laparoscopic Cholecystectomy: A Systematic Review and Meta-Analysis.
Topics: Adrenergic alpha-2 Receptor Agonists; Antihypertensive Agents; Arterial Pressure; Cholecystectomy, L | 2017 |
Clonidine in pediatric anesthesia: the new panacea or a drug still looking for an indication?
Topics: Adrenergic alpha-2 Receptor Agonists; Age Factors; Anesthesia; Child; Clonidine; Emergence Delirium; | 2019 |
Safety and efficacy of clonidine on postoperative vomiting and pain in pediatric ophthalmic surgery: A systematic review and meta-analysis.
Topics: Analgesics; Antiemetics; Child; Clonidine; Humans; Pain, Postoperative; Postoperative Nausea and Vom | 2019 |
Adjuncts to local anaesthetics in tonsillectomy: a systematic review and meta-analysis.
Topics: Anesthetics, Local; Clonidine; Dexamethasone; Humans; Laryngismus; Nerve Block; Pain, Postoperative; | 2017 |
Premedication with clonidine is superior to benzodiazepines. A meta analysis of published studies.
Topics: Adrenergic alpha-Agonists; Anesthesia Recovery Period; Benzodiazepines; Child; Child, Preschool; Clo | 2010 |
Efficacy and safety of clonidine as additive for caudal regional anesthesia: a quantitative systematic review of randomized controlled trials.
Topics: Analgesics; Anesthesia, Caudal; Child; Clonidine; Humans; Pain, Postoperative; Postoperative Nausea | 2011 |
Bayesian enhanced meta-analysis of post-operative analgesic efficacy of additives for caudal analgesia in children.
Topics: Adjuvants, Anesthesia; Adolescent; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Anesthet | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials.
Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia Recovery Period; Clonidine; Dex | 2012 |
Efficacy of adding clonidine to intrathecal morphine in acute postoperative pain: meta-analysis.
Topics: Acute Pain; Adrenergic alpha-Agonists; Analgesics, Opioid; Clonidine; Endpoint Determination; Fentan | 2013 |
Postoperative pain management: can transdermal patches help?
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Antiemetics; Clonidine; Fentanyl; Humans; | 2006 |
26 trials available for clonidine and Emesis, Postoperative
| Article | Year |
|---|---|
Role of Oral Clonidine Premedication on Intra-operative Haemodynamics and PONV in Laparoscopic Cholecystectomy.
Topics: Adult; Analgesics; Bangladesh; Cholecystectomy, Laparoscopic; Clonidine; Double-Blind Method; Hemody | 2017 |
Comparison of Ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after orthognathic surgeries: A triple blind randomized controlled trial.
Topics: Adolescent; Adult; Analgesics; Antiemetics; Clonidine; Double-Blind Method; Female; Humans; Male; On | 2018 |
The impact of a transversus abdominis plane block including clonidine vs. intrathecal morphine on nausea and vomiting after caesarean section: A randomised controlled trial.
Topics: Abdominal Muscles; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; Cesarean | 2019 |
Randomized study of postcesarean analgesia with intrathecal morphine alone or combined with clonidine.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Cesarean Section; Clonidine; Double-Blind Meth | 2016 |
The analgesic effect of epidural clonidine after spinal surgery: a randomized placebo-controlled trial.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Analgesia, Epidural; Blood Pressure; Clonidine; Double-Blind | 2009 |
[Quality of premedication and patient satisfaction after premedication with midazolam, clonidine or placebo : Randomized double-blind study with age-adjusted dosage].
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Aging; Anesthesia; Anxiety; Blood Gas Analysis; | 2010 |
The effect of oral clonidine premedication on nausea and vomiting after ear surgery.
Topics: Administration, Oral; Adult; Clonidine; Double-Blind Method; Ear; Female; Humans; Male; Postoperativ | 2010 |
Effect of epidural clonidine on minimum local anesthetic concentration (ED50) of levobupivacaine for caudal block in children.
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Analgesia, Epidural; Anesthesia, Caudal; Anestheti | 2011 |
Comparison between ropivacaine 1.5 mg ml(-1) plus fentanyl 2 mg ml(-1) and ropivacaine 1.5 mg ml(-1) plus clonidine 1 mg ml(-1) as analgesic solution after anterior cruciate ligament reconstruction: a randomized clinical trial.
Topics: Adrenergic alpha-Agonists; Adult; Amides; Anesthetics, Intravenous; Anesthetics, Local; Anterior Cru | 2011 |
Steal induction in preschool children: is melatonin as good as clonidine? A prospective, randomized study.
Topics: Adrenergic alpha-Agonists; Anesthesia, Inhalation; Child, Preschool; Clonidine; Electroencephalograp | 2013 |
Oral clonidine premedication does not reduce postoperative vomiting in children undergoing strabismus surgery.
Topics: Adrenergic alpha-Agonists; Child; Child, Preschool; Clonidine; Double-Blind Method; Female; Humans; | 2003 |
The addition of droperidol or clonidine to epidural tramadol shortens onset time and increases duration of postoperative analgesia.
Topics: Abdomen; Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Aged; Analgesia, Epidural; Analges | 2003 |
The effect of spinal bupivacaine in combination with either epidural clonidine and/or 0.5% bupivacaine administered at the incision site on postoperative outcome in patients undergoing lumbar laminectomy.
Topics: Adrenergic alpha-Agonists; Aged; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Spina | 2003 |
[Comparison of premedication with clonidine and midazolam combined with TCI for orthopaedic shoulder surgery].
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Adult; Aged; Analgesia, | 2003 |
Epidural infusion of clonidine or clonidine plus ropivacaine for postoperative analgesia in children undergoing major abdominal surgery.
Topics: Abdomen; Adrenergic alpha-Agonists; Amides; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Lo | 2003 |
Analgesic effect of clonidine added to bupivacaine 0.125% in paediatric caudal blockade.
Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia, Caudal; Anesthetics, Local; Bupivacaine; Child, P | 2004 |
General anaesthesia combined with bilateral paravertebral blockade (T5-6) vs. general anaesthesia for laparoscopic cholecystectomy: a prospective, randomized clinical trial.
Topics: Analgesics; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local; Bupivacaine; Cholecystectom | 2004 |
Clonidine vs. midazolam as premedication in children undergoing adeno-tonsillectomy: a prospective, randomized, controlled clinical trial.
Topics: Adenoidectomy; Adrenergic alpha-Agonists; Anesthesia; Behavior; Child; Child, Preschool; Clonidine; | 2004 |
Low-dose ketamine with clonidine and midazolam for adult day care surgery.
Topics: Adrenergic alpha-Agonists; Adult; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesth | 2005 |
[Effects of clonidine and midazolam on postoperative shivering, nausea, and vomiting].
Topics: Administration, Oral; Aged; Anesthesia, Epidural; Anesthesia, General; Clonidine; Female; Humans; Ma | 2005 |
[Femoral nerve block for postoperative analgesia after anterior cruciate ligament reconstruction: comparison of 2 concentrations of bupivacaine with clonidine in 3 modes of administration].
Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Anesthetics, | 2006 |
Clonidine 1 microg/kg is a safe and effective adjuvant to plain bupivacaine in spinal anesthesia in adolescents.
Topics: Adjuvants, Pharmaceutic; Adolescent; Anesthesia, Spinal; Bupivacaine; Child; Clonidine; Double-Blind | 2007 |
[Premedication in maxillofacial surgery under total intravenous anesthesia . Effects of clonidine compared to midazolam on the perioperative course].
Topics: Adjuvants, Anesthesia; Adrenergic alpha-Agonists; Adult; Anesthesia, Intravenous; Clonidine; Double- | 2000 |
Low-dose intrathecal clonidine combined with sufentanil as analgesic drugs in abdominal gynecological surgery.
Topics: Abdomen; Adrenergic alpha-Agonists; Adult; Analgesics; Analgesics, Opioid; Blood Pressure; Clonidine | 2000 |
The efficacy of oral clonidine premedication in the prevention of postoperative vomiting in children following strabismus surgery.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Anesthetics, Combined; Anesthetics, Inhalation; Ane | 2001 |
Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anesthesia, General; Antiemetics; Blood Pressure; Breast Neoplasms; | 2002 |
2 other studies available for clonidine and Emesis, Postoperative
| Article | Year |
|---|---|
Comparison of 2 Methods of Local Anesthetic-Based Injection as Part of a Multimodal Approach to Pain Management After Total Knee Arthroplasty.
Topics: Aged; Amides; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, | 2015 |
Use of intravenous midazolam and clonidine in cyclical vomiting syndrome: a case report.
Topics: Adrenergic alpha-Agonists; Child; Clonidine; Drug Therapy, Combination; Humans; Hypnotics and Sedati | 2005 |