Page last updated: 2024-10-25

clonidine and Emergencies

clonidine has been researched along with Emergencies in 48 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Emergencies: Situations or conditions requiring immediate intervention to avoid serious adverse results.

Research Excerpts

ExcerptRelevanceReference
"This study was designed to compare the clinical efficacy and safety of oral clonidine and oral labetalol in the treatment of severe hypertension in an emergency department setting."9.07Oral labetalol versus oral clonidine in the emergency treatment of severe hypertension. ( Atkin, SH; Beaty, P; Cuffie, C; Jaker, MA; Quadrel, MA; Soto-Greene, ML, 1992)
"Fifty-one patients with urgent hypertension were treated in the emergency department with either oral nifedipine or oral clonidine in a randomized double-blind prospective study."9.06Oral nifedipine vs oral clonidine in the treatment of urgent hypertension. ( Atkin, S; Brosch, F; Jaker, M; Schmid, G; Soto, M, 1989)
"The case of a 59-year-old healthy woman is described, who developed an extreme sinus bradycardia (30/min) with chest pain and acute right heart failure associated with gastrointestinal symptoms and elevation of the liver enzymes while simultaneously taking tizanidine (Sirdalud), diclofenac (Voltaren), and rofecoxib (Vioxx)."7.73[Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)]. ( Bertoli, R; Caduff Janosa, P; Cerny, A; Kick, A; Moschovitis, G, 2005)
"Clonidine was administered by intravenous infusion to 12 patients classified as having exaggerated arterial hypertension, their systolic (SAP), diastolic (DAP) and mean (MAP) arterial pressures were significantly reduced from the third min."7.66Acute hypotensive action of clonidine after intravenous infusion in hypertensive emergencies. ( Fragachán, F; Monsalve, P; Pérez, J; Pérez-Acuña, F; Sanabria, A; Tremarias, A, 1983)
"Nineteen patients with severe essential hypertension or hypertension due to renal parenchymal disease were treated with intravenous clonidine."7.66Evaluation of intravenous clonidine in hypertensive emergencies. ( Niarchos, AP, 1978)
"Nitrendipine is a new calcium antagonist of the 1,4-dihydropyridine group with strong vasodilating properties."6.66Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate. ( Grosser, KD; Späh, F, 1988)
"Nifedipine is a simple, effective, and safe alternative drug for managing hypertensive emergencies, especially when continuous monitoring of the patient cannot be guaranteed."6.65Nifedipine in hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC; Lang, C; Müller, J; Radü, EW, 1983)
"A major risk associated with the acute treatment of severe hypertension is a reduction in cerebral blood flow (CBF) with ischemic injury to the central nervous system."5.28Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine. ( Brown, FD; Cervenka, K; Greene, CS; Gretler, DD; McCoy, CE; Murphy, MB, 1990)
"This study was designed to compare the clinical efficacy and safety of oral clonidine and oral labetalol in the treatment of severe hypertension in an emergency department setting."5.07Oral labetalol versus oral clonidine in the emergency treatment of severe hypertension. ( Atkin, SH; Beaty, P; Cuffie, C; Jaker, MA; Quadrel, MA; Soto-Greene, ML, 1992)
"Fifty-one patients with urgent hypertension were treated in the emergency department with either oral nifedipine or oral clonidine in a randomized double-blind prospective study."5.06Oral nifedipine vs oral clonidine in the treatment of urgent hypertension. ( Atkin, S; Brosch, F; Jaker, M; Schmid, G; Soto, M, 1989)
"The authors report a clinical case of clonidine poisoning in a 20-month-old child."4.79[Coma with miosis and bradycardia]. ( Matos, LD; Porfírio, H, 1994)
" In this report, we describe a 15-year-old adolescent girl who experienced continued delirium 5 days after an overdose of quetiapine, trazodone, and clonidine."3.76Prolonged delirium after quetiapine overdose. ( Pedapati, EV; Rhyee, SH; Thompson, J, 2010)
"The case of a 59-year-old healthy woman is described, who developed an extreme sinus bradycardia (30/min) with chest pain and acute right heart failure associated with gastrointestinal symptoms and elevation of the liver enzymes while simultaneously taking tizanidine (Sirdalud), diclofenac (Voltaren), and rofecoxib (Vioxx)."3.73[Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)]. ( Bertoli, R; Caduff Janosa, P; Cerny, A; Kick, A; Moschovitis, G, 2005)
"The efficacy and safety of 20 mg of nifedipine as a single oral dose have been studied with respect to the use of the drug as an alternative treatment of hypertensive emergencies."3.66An oral calcium antagonist for treatment of hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC, 1982)
"Clonidine was administered by intravenous infusion to 12 patients classified as having exaggerated arterial hypertension, their systolic (SAP), diastolic (DAP) and mean (MAP) arterial pressures were significantly reduced from the third min."3.66Acute hypotensive action of clonidine after intravenous infusion in hypertensive emergencies. ( Fragachán, F; Monsalve, P; Pérez, J; Pérez-Acuña, F; Sanabria, A; Tremarias, A, 1983)
"Nineteen patients with severe essential hypertension or hypertension due to renal parenchymal disease were treated with intravenous clonidine."3.66Evaluation of intravenous clonidine in hypertensive emergencies. ( Niarchos, AP, 1978)
"Nitrendipine is a new calcium antagonist of the 1,4-dihydropyridine group with strong vasodilating properties."2.66Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate. ( Grosser, KD; Späh, F, 1988)
"Nifedipine is a simple, effective, and safe alternative drug for managing hypertensive emergencies, especially when continuous monitoring of the patient cannot be guaranteed."2.65Nifedipine in hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC; Lang, C; Müller, J; Radü, EW, 1983)
"A major risk associated with the acute treatment of severe hypertension is a reduction in cerebral blood flow (CBF) with ischemic injury to the central nervous system."1.28Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine. ( Brown, FD; Cervenka, K; Greene, CS; Gretler, DD; McCoy, CE; Murphy, MB, 1990)
"Tolazoline was found to be ineffective in reversing symptoms and signs of clonidine overdosage."1.27Management of clonidine ingestion in children. ( Olsson, JM; Pruitt, AW, 1983)
" The dosage of clonidine was progressively increased until a normal blood pressure (mean blood pressure less than or equal to 105 mm Hg) was obtained."1.27Treatment of hypertensive emergencies: classic and newer approaches. ( Bisi, G; Gallini, C; Masotti, G; Neri Serneri, GG; Poggesi, L; Scarti, L; Sciagrà, R, 1986)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199031 (64.58)18.7374
1990's9 (18.75)18.2507
2000's4 (8.33)29.6817
2010's4 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sullivan, RW1
Ryzewski, M1
Holland, MG1
Marraffa, JM1
Allen, NM1
Lin, JP1
Lynch, T1
King, MD1
Malaty, J1
Malaty, IA1
Rhyee, SH1
Pedapati, EV1
Thompson, J1
Stiefelhagen, P1
Kick, A1
Bertoli, R1
Moschovitis, G1
Caduff Janosa, P1
Cerny, A1
Moser, M1
Izzo, JL1
Bisognano, J1
Füessl, HS1
Seliuzhitskiĭ, NS1
Olsson, JM1
Pruitt, AW1
Conen, D2
Bertel, O2
Dubach, UC2
Ram, CV2
Radü, EW1
Müller, J1
Lang, C1
Pérez-Acuña, F1
Monsalve, P1
Pérez, J2
Tremarias, A1
Sanabria, A1
Fragachán, F1
Scarti, L2
Galanti, G1
Poggesi, L2
Sciagrà, R2
Masotti, G2
Hui, KK1
Segal, JL1
Dunn, FG1
Messerli, FH1
Dreslinski, GR1
Anderson, RJ1
Hart, GR1
Crumpler, CP1
Reed, WG1
Matthews, CA1
Prattichizzo, FA1
Galetta, F1
Bonechi, I1
Giusti, C1
Waldfahrer, F1
Leuwer, A1
Krause, J1
Iro, H1
Guríanov, VA1
Dolina, OA1
Tiukov, VL1
Bolśhakova, TD1
Aliautdin, RN1
Porfírio, H1
Matos, LD1
Epstein, M1
Nies, AS1
Rowe, WS1
Anshelevich, IuV1
Raĭbart, IaIa1
Panov, IP1
Zveĭnietse, RA1
Orshanskiĭ, EM1
Niarchos, AP1
Bock, KD1
Atkin, SH1
Jaker, MA1
Beaty, P1
Quadrel, MA1
Cuffie, C1
Soto-Greene, ML1
Naber, M1
Franz, W1
Overbeck, W1
Greene, CS1
Gretler, DD1
Cervenka, K1
McCoy, CE1
Brown, FD1
Murphy, MB1
Wedin, GP1
Richardson, SL1
Wallace, GH1
Bisi, G1
Gallini, C1
Neri Serneri, GG1
Späh, F1
Grosser, KD1
Ferguson, RK2
Vlasses, PH2
Jaker, M1
Atkin, S1
Soto, M1
Schmid, G1
Brosch, F1
Houston, MC2
Feldstein, JS1
Karachalios, GN1
Meese, RB1
Guffanti, E1
Vaccarella, A1
Meregalli, M1
Fiorella, G1
Chierichetti, SM1
Mazzola, C1
Burris, JF1
Philipp, T1
Nast, HP1
Vidt, DG1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine[NCT03096444]Phase 213 participants (Actual)Interventional2017-05-23Terminated (stopped due to Efficacy was not seen after interim analysis)
Hemodynamic Effect of Intrathecal Clonidine in Hypertensive Subjects: A Pilot Study to Assess Its Effectiveness in Hypertensive Subjects With Poor Blood Pressure Control (Phase II)[NCT01297335]Phase 210 participants (Actual)Interventional2011-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Peak Itch Intensity Between the Vehicle and Active Treatments (Individual and KeAmLi-combo).

"Peak itch intensity between the vehicle and 4 other active treatments (individual ketamine, amitriptyline, or lidocaine, and KeAmLi-combo). Itch intensity was measured on a 100mm scale visual analog scale for 10 minutes. 0 was weighted with no itch and 100 was weighted with most itch imaginable." (NCT03096444)
Timeframe: 10 minutes

InterventionIntensity score (Mean)
Topical KeAmLi Combo62.7
Topical Ketamine63.1
Topical Amitriptyline69.2
Topical Lidocaine65.8
Topical Vehicle61.9

Mechanical Thresholds (Mechanical Detection and Pain).

Assess mechanical detection and pain thresholds using von Frey filaments stimulators (measured in force mN) to calculate the final threshold as the geometric mean of five series of ascending and descending stimuli. (NCT03096444)
Timeframe: 5 minutes

,,,,
InterventionmN (Mean)
Mechanical Detection ThresholdMechanical Pain Threshold
Topical Amitriptyline3.573423965152.4768146
Topical KeAmLi Combo3.519376956152.3293608
Topical Ketamine3.464204768135.9
Topical Lidocaine3.546037659126.9
Topical Vehicle3.525692637148.7138273

Thermal Threshold Detection (Warmth and Heat Pain)

Two standardized quantitative sensory tests are performed to measure warmth detection threshold (assesses the threshold of which warmth sensation is first detected) and heat pain threshold (assesses the threshold at which heat pain sensation is first detected). Measured in change in celsius. (NCT03096444)
Timeframe: 3 minutes

,,,,
InterventionDegrees celsius (Mean)
Warm Detection ThresholdHeat Pain Threshold
Topical Amitriptyline33.940.0
Topical KeAmLi Combo33.639.8
Topical Ketamine34.040.0
Topical Lidocaine33.739.4
Topical Vehicle33.839.7

Change in Blood Pressure After Intrathecal Injection of Clonidine.

"Subjects baseline blood pressure (systolic blood pressure (SBP), and diastolic blood pressure (DBP)), and blood pressures after clonidine injection was compared against baseline to assess efficacy of clonidine in refractory hypertensive subjects. Subject's blood pressure was monitored continuously after intrathecal injection of clonidine until subjects blood pressure nadir and return to pre clonidine injection level. The mean value reported below are the average changes in blood pressure from baseline (pre clonidine injection) in both SBP and DBP during post clonidine injection blood pressure monitoring for 4 hours.~Blood pressure measurements were collected every 10 minutes for first hour after injection, and every 15 minutes after the first hour, up to 4 hours were averaged to report the change from baseline." (NCT01297335)
Timeframe: Baseline, Every 10 Minutes for first hour after clonidine injection, and every 15 minutes after first hour, until 4 hours after clonidine injection

Interventionmm Hg (Mean)
Change in mean SBP after clonidine injectionChange in DBP after clonidine injection
Intrathecal Clonidine7937

Changes in Visual Analogue Scale (VAS) Ratings of Sedation and Sensation of Dry Mouth Reported by the Subjects, Pre and 1 Hour Post Injection

Subjects were asked to rate severity of two of the most common side effects of clonidine, sedation and sensation of dry mouth, at pre and post (1 hour after) intrathecal administration of clonidine. The mean changes between pre and post injection VAS ratings of sedation and sensation of dry mouth are reported below. The VAS scale ranges from 1 to 10 cm, with higher values indicating higher level of sedation and higher level of dry mouth. (NCT01297335)
Timeframe: Before clonidine injection (Baseline), and at 1 hour after clonidine injection.

Interventioncm (Mean)
Change in level of sedationChange in sensation of dry mouth
Intrathecal Clonidine3.363.47

Likert Scale Pain Rating

Likert scale is 11 point digital pain rating system that asks subjects to rate their pain from 0 to 10. Rating of 0 means no pain at all, and in increasing order, 10 would mean worst pain imaginable/ unbearable pain. (NCT01297335)
Timeframe: Pre-dose and 1 hour post injection.

Interventionunits on a scale (Mean)
Pre-injection average Likert scorePost-injection average Likert score
Intrathecal Clonidine6.53.6

Reviews

11 reviews available for clonidine and Emergencies

ArticleYear
Status dystonicus: a practice guide.
    Developmental medicine and child neurology, 2014, Volume: 56, Issue:2

    Topics: Adolescent; Baclofen; Child; Child, Preschool; Chloral Hydrate; Clonidine; Combined Modality Therapy

2014
Hypertensive crisis.
    Cardiology clinics, 1984, Volume: 2, Issue:2

    Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia

1984
Hypertensive emergencies: practical approach to treatment.
    Postgraduate medicine, 1980, Volume: 68, Issue:2

    Topics: Administration, Oral; Antihypertensive Agents; Child; Clonidine; Diazoxide; Emergencies; Female; Hum

1980
[Coma with miosis and bradycardia].
    Acta medica portuguesa, 1994, Volume: 7, Issue:3

    Topics: Bradycardia; Clonidine; Coma; Diagnosis, Differential; Emergencies; Female; Humans; Infant; Miosis;

1994
Diagnosis and management of hypertensive emergencies.
    Clinical cornerstone, 1999, Volume: 2, Issue:1

    Topics: Adrenergic alpha-Agonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aortic

1999
Clinical pharmacology of antihypertensive drugs.
    The Medical clinics of North America, 1977, Volume: 61, Issue:3

    Topics: Adrenergic alpha-Antagonists; Aldosterone; Angiotensin II; Antihypertensive Agents; Bethanidine; Blo

1977
Hypertensive emergencies and urgencies.
    JAMA, 1986, Mar-28, Volume: 255, Issue:12

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers;

1986
The comparative effects of clonidine hydrochloride and nifedipine in the treatment of hypertensive crises.
    American heart journal, 1988, Volume: 115, Issue:1 Pt 1

    Topics: Clonidine; Emergencies; Humans; Hypertension; Nifedipine

1988
Treatment of hypertensive emergencies and urgencies with oral clonidine loading and titration. A review.
    Archives of internal medicine, 1986, Volume: 146, Issue:3

    Topics: Blood Pressure; Cardiovascular Diseases; Clonidine; Drug Administration Schedule; Emergencies; Human

1986
Hypertensive cardiovascular emergencies.
    Comprehensive therapy, 1985, Volume: 11, Issue:10

    Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia

1985
Choice of antihypertensive drugs for the treatment of hypertension, including hypertensive emergencies.
    Cardiovascular clinics, 1974, Volume: 6, Issue:2

    Topics: Antihypertensive Agents; Bethanechol Compounds; Clonidine; Diazoxide; Diuretics; Emergencies; Ferric

1974

Trials

6 trials available for clonidine and Emergencies

ArticleYear
Nifedipine in hypertensive emergencies.
    British medical journal (Clinical research ed.), 1983, Jan-01, Volume: 286, Issue:6358

    Topics: Adult; Aged; Blood Pressure; Cerebrovascular Circulation; Clinical Trials as Topic; Clonidine; Emerg

1983
[Use of clofelin for arresting hypertensive crises].
    Kardiologiia, 1978, Volume: 18, Issue:11

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Diastole; Drug Evaluation; Emergen

1978
Oral labetalol versus oral clonidine in the emergency treatment of severe hypertension.
    The American journal of the medical sciences, 1992, Volume: 303, Issue:1

    Topics: Administration, Oral; Blood Pressure; Clonidine; Diastole; Emergencies; Female; Heart Rate; Humans;

1992
Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate.
    Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 4

    Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy, Combination; Emerg

1988
Oral nifedipine vs oral clonidine in the treatment of urgent hypertension.
    Archives of internal medicine, 1989, Volume: 149, Issue:2

    Topics: Administration, Oral; Adult; Aged; Clonidine; Double-Blind Method; Emergencies; Female; Humans; Hype

1989
A single blind comparison of dihydroergotoxine mesilate and clonidine for treatment of hypertensive emergencies.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:9

    Topics: Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Dihydroergotoxine; Drug Tolerance; Emerge

1985

Other Studies

31 other studies available for clonidine and Emergencies

ArticleYear
Compounded ointment results in severe toxicity in a pediatric patient.
    Pediatric emergency care, 2013, Volume: 29, Issue:11

    Topics: Administration, Cutaneous; Amines; Analgesics; Body Surface Area; Bradycardia; Clonidine; Combined M

2013
Hypertensive urgency: an important aetiology of rebound hypertension.
    BMJ case reports, 2014, Oct-21, Volume: 2014

    Topics: Adrenergic alpha-2 Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Emergen

2014
Prolonged delirium after quetiapine overdose.
    Pediatric emergency care, 2010, Volume: 26, Issue:10

    Topics: Adolescent; Antipsychotic Agents; Cholinergic Antagonists; Clonidine; Cytochrome P-450 CYP3A; Deliri

2010
[When hypertension becomes an emergency case: lower the blood pressure, but slowly!].
    MMW Fortschritte der Medizin, 2003, May-29, Volume: 145, Issue:22

    Topics: Administration, Oral; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diagnosis, Diffe

2003
[Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)].
    Medizinische Klinik (Munich, Germany : 1983), 2005, Apr-15, Volume: 100, Issue:4

    Topics: Acute Disease; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Bradycardia; Clonidine; Cyclooxy

2005
Hypertensive emergencies.
    Journal of clinical hypertension (Greenwich, Conn.), 2006, Volume: 8, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clonidine; Diuretics;

2006
[Emergency checklist in hypertensive crisis].
    MMW Fortschritte der Medizin, 2006, Jun-22, Volume: 148, Issue:25

    Topics: Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Clonidine; Diuretic

2006
[Pyrroxan and clofelin effectiveness in hypertensive crises].
    Vrachebnoe delo, 1982, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Clonidine; Dioxanes; Dioxins; Drug Evaluation; Emergencie

1982
Management of clonidine ingestion in children.
    The Journal of pediatrics, 1983, Volume: 103, Issue:4

    Topics: Atropine; Blood Pressure; Charcoal; Child, Preschool; Clonidine; Coma; Dopamine; Emergencies; Female

1983
An oral calcium antagonist for treatment of hypertensive emergencies.
    Journal of cardiovascular pharmacology, 1982, Volume: 4 Suppl 3

    Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clonidine; Emergencies; Female; Heart Rate; Humans;

1982
Acute hypotensive action of clonidine after intravenous infusion in hypertensive emergencies.
    European journal of clinical pharmacology, 1983, Volume: 25, Issue:2

    Topics: Adult; Aged; Blood Pressure; Clonidine; Electrocardiography; Emergencies; Female; Heart Rate; Humans

1983
[Clonidine in the treatment of hypertensive emergencies].
    Cardiologia (Rome, Italy), 1983, Volume: 28, Issue:12

    Topics: Adult; Aged; Blood Pressure; Clonidine; Drug Evaluation; Drug Tolerance; Emergencies; Female; Humans

1983
Hypertensive crisis induced by interaction of clonidine with imipramine.
    Journal of the American Geriatrics Society, 1983, Volume: 31, Issue:3

    Topics: Aged; Clonidine; Drug Interactions; Emergencies; Female; Humans; Hypertension; Imipramine; Time Fact

1983
Clonidine in hypertensive urgencies.
    JAMA, 1982, Mar-05, Volume: 247, Issue:9

    Topics: Clonidine; Emergencies; Humans; Hypertension

1982
Oral clonidine loading in hypertensive urgencies.
    JAMA, 1981, Aug-21, Volume: 246, Issue:8

    Topics: Administration, Oral; Adult; Blood Pressure; Clonidine; Emergencies; Female; Humans; Hypertension; M

1981
[Therapy of arterial hypertension associated with acute stroke. Current trends and problems].
    La Clinica terapeutica, 1994, Volume: 145, Issue:11

    Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure Monitors; Cerebral Hemorrhage; Cerebrov

1994
[Severe oropharyngeal angioedema caused by ACE inhibitor. A case report].
    HNO, 1995, Volume: 43, Issue:1

    Topics: Angioedema; Clemastine; Clonidine; Combined Modality Therapy; Drug Hypersensitivity; Emergencies; En

1995
[Experience with the use of clopheline in geriatric anesthesiology].
    Khirurgiia, 1993, Issue:12

    Topics: Aged; Aged, 80 and over; Anesthesia, Endotracheal; Barbiturates; Bile Duct Diseases; Catecholamines;

1993
Some aspects of the management of hypertension. 1. General considerations.
    The Medical journal of Australia, 1975, Feb-22, Volume: 1, Issue:8

    Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clonidine; Dia

1975
Evaluation of intravenous clonidine in hypertensive emergencies.
    Journal of clinical pharmacology, 1978, Volume: 18, Issue:4

    Topics: Adult; Aged; Clonidine; Dose-Response Relationship, Drug; Emergencies; Female; Humans; Hypertension;

1978
[Treatment of hypertensive emergencies].
    Medizinische Klinik, 1978, Mar-17, Volume: 73, Issue:11

    Topics: Clonidine; Diazoxide; Emergencies; Family Practice; Furosemide; Hospitalization; Humans; Hypertensio

1978
[Characteristics of alcohol withdrawal delirium in surgical patients and recommendations for treatment].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1991, Volume: 62, Issue:2

    Topics: Adult; Aged; Alcohol Withdrawal Delirium; Blood Pressure; Clonidine; Combined Modality Therapy; Emer

1991
Cerebral blood flow during the acute therapy of severe hypertension with oral clonidine.
    The American journal of emergency medicine, 1990, Volume: 8, Issue:4

    Topics: Administration, Oral; Blood Pressure; Cerebrovascular Circulation; Clonidine; Emergencies; Female; H

1990
Clonidine poisoning in children.
    American journal of diseases of children (1960), 1990, Volume: 144, Issue:8

    Topics: Child, Preschool; Clonidine; Drug Overdose; Emergencies; Humans; Male

1990
Treatment of hypertensive emergencies: classic and newer approaches.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 3

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clonidine; Emergencies; Female; Heart Rate; Hu

1986
How urgent is 'urgent' hypertension?
    Archives of internal medicine, 1989, Volume: 149, Issue:2

    Topics: Clonidine; Emergencies; Hospitalization; Humans; Hypertension; Nifedipine

1989
Hypertensive emergencies.
    Primary care, 1986, Volume: 13, Issue:1

    Topics: Adrenal Gland Neoplasms; Angina Pectoris; Antihypertensive Agents; Aortic Aneurysm; Aortic Dissectio

1986
Hypertensive emergencies treated with oral clonidine.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:2

    Topics: Adult; Clonidine; Emergencies; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged

1986
Drugs for hypertensive emergencies.
    The Medical letter on drugs and therapeutics, 1985, Mar-01, Volume: 27, Issue:682

    Topics: Administration, Oral; Captopril; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hypertensio

1985
Hypertensive emergencies.
    American family physician, 1985, Volume: 32, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hyp

1985
[Hypertensive emergencies].
    Der Internist, 1974, Volume: 15, Issue:3

    Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies;

1974