clonidine has been researched along with Dyskinesia, Drug-Induced in 24 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clonidine was selected because it blocks noradrenergic but not dopaminergic neurotransmission." | 6.65 | Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs. ( Adler, LE; Bell, J; Denver, P; Freedman, R; Kirch, D; Pachtman, E; Pecevich, M, 1982) |
| "Clonidine's actions and efficacy in mental disorders are reviewed and examined." | 5.06 | Psychiatric indications for clonidine: the neuropharmacologic and clinical basis. ( Bond, WS, 1986) |
| " The aims of this study were therefore (1) to investigate the anti-dyskinetic effects of piribedil on L-DOPA-induced contralateral turning behaviour, locomotive dyskinesias (LD), axial dystonia (AD), orolingual dyskinesia (OD) and forelimb dyskinesia (FD) and (2) to compare these effects to the α(2) adrenoceptor antagonist, idazoxan, or the α(2) adrenoceptor agonist, clonidine." | 3.79 | The effect of piribedil on L-DOPA-induced dyskinesias in a rat model of Parkinson's disease: differential role of α(2) adrenergic mechanisms. ( Gerlach, M; Halley, P; Riederer, P; van den Buuse, M, 2013) |
| "Twenty-nine patients with tardive dyskinesia (n = 20) or related syndromes [spontaneous dyskinesia (n = 3), levodopa-induced dyskinesia (n = 3), tardive dystonia (n = 3)] were treated with clonidine." | 3.67 | Clonidine therapy for tardive dyskinesia and related syndromes. ( Koga, I; Nishikawa, T; Tanaka, M; Tsuda, A; Uchida, Y, 1984) |
| "Three cases of tardive dyskinesia with psychotic symptoms (one presenile psychosis; two schizophrenia) were successfully treated with both clonidine and neuroleptics for 3 years." | 3.66 | Combined treatment of tardive dyskinesia with clonidine and neuroleptics: a follow-up study of three cases for three years. ( Koga, I; Nishikawa, T; Tanaka, M; Uchida, Y, 1983) |
| "Clonidine was administered to twelve chronic schizophrenic patients with TDS in a double-blind, cross-over, single-dose trial." | 2.66 | Clonidine trial in tardive dyskinesia. Therapeutic response, MHPG, and plasma DBH. ( Markianos, M; Tripodianakis, J, 1986) |
| "Clonidine was selected because it blocks noradrenergic but not dopaminergic neurotransmission." | 2.65 | Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs. ( Adler, LE; Bell, J; Denver, P; Freedman, R; Kirch, D; Pachtman, E; Pecevich, M, 1982) |
| "Baclofen was also useful in one monkey against a more dystonic form of dyskinesia." | 1.29 | Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys. ( Bédard, PJ; Gomez-Mancilla, B, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (62.50) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ostock, CY | 1 |
| Hallmark, J | 1 |
| Palumbo, N | 1 |
| Bhide, N | 1 |
| Conti, M | 1 |
| George, JA | 1 |
| Bishop, C | 1 |
| Gerlach, M | 1 |
| Halley, P | 1 |
| Riederer, P | 1 |
| van den Buuse, M | 1 |
| McGavin, CL | 1 |
| John, V | 1 |
| Musser, WS | 1 |
| Freedman, R | 2 |
| Bell, J | 2 |
| Kirch, D | 2 |
| Nishikawa, T | 3 |
| Tanaka, M | 3 |
| Koga, I | 3 |
| Uchida, Y | 3 |
| Adler, LE | 1 |
| Pecevich, M | 1 |
| Pachtman, E | 1 |
| Denver, P | 1 |
| Johnson, JM | 1 |
| Tsuda, A | 1 |
| Lechin, F | 1 |
| van der Dijs, B | 1 |
| Gomez-Mancilla, B | 1 |
| Bédard, PJ | 1 |
| Kazamatsuri, H | 1 |
| Henry, B | 1 |
| Crossman, AR | 1 |
| Brotchie, JM | 1 |
| Maj, J | 1 |
| Rogóz, Z | 1 |
| Dlaboga, D | 1 |
| Dziedzicka-Wasylewska, M | 1 |
| Tanii, H | 1 |
| Hayashi, M | 1 |
| Hashimoto, K | 1 |
| Sachdev, P | 1 |
| Chee, KY | 1 |
| Singh, S | 1 |
| Subramaniam, M | 1 |
| Browne, J | 1 |
| Silver, H | 1 |
| Martin, R | 1 |
| Hart, R | 1 |
| Mergener, M | 1 |
| Williams, P | 1 |
| Svensson, TH | 1 |
| Khot, V | 1 |
| Goodwin, J | 1 |
| Wandry, G | 1 |
| Cadet, JL | 1 |
| Braun, T | 1 |
| Freed, WJ | 1 |
| Troung, DD | 1 |
| Bressman, S | 1 |
| Shale, H | 1 |
| Fahn, S | 1 |
| Bond, WS | 1 |
| Tripodianakis, J | 1 |
| Markianos, M | 1 |
3 reviews available for clonidine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; | 1984 |
[Tardive dyskinesia--diagnosis and treatment].
Topics: Clonidine; Diagnosis, Differential; Dyskinesia, Drug-Induced; Humans; Middle Aged; Psychotropic Drug | 1993 |
Clonidine in abstinence reactions: basic mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Anxiety Disorders; Autonomic Nervous System; Central Nervous Sys | 1986 |
7 trials available for clonidine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs.
Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; | 1982 |
Psychiatric uses of antiadrenergic and adrenergic blocking drugs.
Topics: Adult; Alcohol Amnestic Disorder; Antipsychotic Agents; Bipolar Disorder; Clinical Trials as Topic; | 1984 |
Pharmacological characterization of tardive akathisia.
Topics: Administration, Oral; Aged; Akathisia, Drug-Induced; Antipsychotic Agents; Arousal; Atenolol; Benztr | 1990 |
The use of clonidine in the treatment of neuroleptic-induced tardive dyskinesia.
Topics: Adult; Antipsychotic Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Double-Blind Metho | 1986 |
Clonazepam, haloperidol, and clonidine in tic disorders.
Topics: Child; Clinical Trials as Topic; Clonazepam; Clonidine; Drug Therapy, Combination; Dyskinesia, Drug- | 1988 |
Psychiatric indications for clonidine: the neuropharmacologic and clinical basis.
Topics: Animals; Anxiety; Bipolar Disorder; Clinical Trials as Topic; Clonidine; Double-Blind Method; Drug T | 1986 |
Clonidine trial in tardive dyskinesia. Therapeutic response, MHPG, and plasma DBH.
Topics: Adult; Clinical Trials as Topic; Clonidine; Dopamine beta-Hydroxylase; Double-Blind Method; Dyskines | 1986 |
15 other studies available for clonidine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Modulation of L-DOPA's antiparkinsonian and dyskinetic effects by α2-noradrenergic receptors within the locus coeruleus.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Antiparkinso | 2015 |
The effect of piribedil on L-DOPA-induced dyskinesias in a rat model of Parkinson's disease: differential role of α(2) adrenergic mechanisms.
Topics: Adrenergic Agents; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; An | 2013 |
Levetiracetam as a treatment for tardive dyskinesia: a case report.
Topics: Adrenergic alpha-Agonists; Anticonvulsants; Antidepressive Agents; Chronic Disease; Clonidine; Depre | 2003 |
Clonidine therapy for coexisting psychosis and tardive dyskinesia.
Topics: Adult; Antipsychotic Agents; Clonidine; Dyskinesia, Drug-Induced; Female; Humans; Male; Schizophreni | 1980 |
Combined treatment of tardive dyskinesia with clonidine and neuroleptics: a follow-up study of three cases for three years.
Topics: Antipsychotic Agents; Clonidine; Dementia; Dyskinesia, Drug-Induced; Female; Follow-Up Studies; Huma | 1983 |
Clonidine therapy for tardive dyskinesia and related syndromes.
Topics: Adult; Aged; Clonidine; Dyskinesia, Drug-Induced; Dystonia; Female; Humans; Levodopa; Male; Middle A | 1984 |
Tardive dyskinesia treated with clonidine.
Topics: Adult; Aged; Clonidine; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged | 1980 |
Clonidine therapy for psychosis and tardive dyskinesia.
Topics: Clonidine; Dyskinesia, Drug-Induced; Humans; Psychotic Disorders | 1981 |
Effect of nondopaminergic drugs on L-dopa-induced dyskinesias in MPTP-treated monkeys.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Atropine; Baclofen; Clonidine; Dopamine Agent | 1993 |
Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antiparkinson Agents; Behavior, An | 1998 |
Pharmacological effects of milnacipran, a new antidepressant, given repeatedly on the alpha1-adrenergic and serotonergic 5-HT2A systems.
Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Adrenergic Uptake Inhibitors; Aggression; Amphetamin | 2000 |
Effects of neurotropic agents with a selectivity for alpha-adrenoceptors on nitrile-induced dyskinetic syndrome in mice.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Dyskinesia, Drug-Induce | 1990 |
Failure of clonidine in tardive dystonia: implications for nosology.
Topics: Adult; Antipsychotic Agents; Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; | 1989 |
Time course of effects of clonidine.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Clonidine; Dyskinesia, Drug-Induced; Humans; Psychomo | 1987 |
Clonidine and prazosin block the iminodipropionitrile (IDPN)-induced spasmodic dyskinetic syndrome in mice.
Topics: Animals; Clonidine; Dyskinesia, Drug-Induced; Male; Mice; Nitriles; Norepinephrine; Prazosin; Recept | 1987 |