Page last updated: 2024-10-25

clonidine and Dwarfism, Pituitary

clonidine has been researched along with Dwarfism, Pituitary in 23 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Dwarfism, Pituitary: A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from the HYPOTHALAMUS or from the mutations in the growth hormone gene (GH1) in the PITUITARY GLAND. It is also known as Type I pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of HUMAN GROWTH HORMONE during development.

Research Excerpts

ExcerptRelevanceReference
" Now, we sought to determine if we could detect a GH response to hypoglycemia (ITT: insulin tolerance test) or clonidine (CL) in these patients."9.12GH response to hypoglycemia and clonidine in the GH-releasing hormone resistance syndrome. ( Aguiar-Oliveira, MH; Almeida, JC; Britto, AV; Farias, CT; Oliveira, CR; Oliveira, JL; Parmigiani, G; Prado, CM; Salvatori, R; Serpa, MG; Vicente, TA, 2006)
" We have studied the effect of oral clonidine, insulin hypoglycemia, and exercise on plasma hGH and GHRH levels in 31 healthy short-stature children."7.68Effect of oral clonidine, insulin-induced hypoglycemia and exercise on plasma GHRH levels in short-stature children. ( Gil-Ad, I; Josefsberg, Z; Laron, Z; Leibowitch, N; Wasserman, M, 1990)
" Now, we sought to determine if we could detect a GH response to hypoglycemia (ITT: insulin tolerance test) or clonidine (CL) in these patients."5.12GH response to hypoglycemia and clonidine in the GH-releasing hormone resistance syndrome. ( Aguiar-Oliveira, MH; Almeida, JC; Britto, AV; Farias, CT; Oliveira, CR; Oliveira, JL; Parmigiani, G; Prado, CM; Salvatori, R; Serpa, MG; Vicente, TA, 2006)
" We have studied the effect of oral clonidine, insulin hypoglycemia, and exercise on plasma hGH and GHRH levels in 31 healthy short-stature children."3.68Effect of oral clonidine, insulin-induced hypoglycemia and exercise on plasma GHRH levels in short-stature children. ( Gil-Ad, I; Josefsberg, Z; Laron, Z; Leibowitch, N; Wasserman, M, 1990)
"Serum growth hormone (GH) was determined in 15 children (three with normal height, one with pituitary dwarfism, and eleven with short stature without endocrinological disturb) after oral clonidine load of 0,15 mg/m2 S."3.66[Oral clonidine test for growth hormone release (author's transl)]. ( Aparicio Palomino, A; Cardesa García, JJ; Cruz Ortega, J; Espinosa Ruiz-Cabal, J; Moreno Romero, F; Requena Guerrero, F, 1981)
"As clonidine is a well-known effector of the autonomous system, stimulating vagal tone and decreasing sympathetic activity, we compared the autonomous reactions of children with constitutional growth delay (CGD), growth hormone deficiency (GHD) and former small for gestational age (SGA)."1.42Modified Clonidine Testing for Growth Hormone Stimulation Reveals α2-Adrenoreceptor Sub Sensitivity in Children with Idiopathic Growth Hormone Deficiency. ( Buchhorn, R; Meint, S; Rager, K; Willaschek, C, 2015)
"Levodopa and clonidine were given, and blood was drawn for determining serum GH levels."1.29Hypothalamic versus pituitary dysfunction in Down's syndrome as cause of growth retardation. ( Beaulieu, I; Castells, S; Gelato, MC; Torrado, C; Wisniewski, KE; Zarny, S, 1996)
" The extent of the activation seems to depend on the dosage of clonidine."1.27[Activation of the kallikrein-kinin system by clonidine]. ( Hinkel, GK; Kühne, H; Lehmann, B; Scheuch, DW; Schlagehan, IM, 1984)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19903 (13.04)18.7374
1990's7 (30.43)18.2507
2000's6 (26.09)29.6817
2010's4 (17.39)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Sodero, G2
Mariani, F2
Caprarelli, M2
Agazzi, C2
Quarta, L2
Benacquista, L2
Rigante, D2
Clelia, C2
Richmond, E1
Rogol, AD1
Yackobovitch-Gavan, M1
Lazar, L1
Diamant, R1
Phillip, M1
Oron, T1
Ibba, A1
Guzzetti, C1
Casula, L1
Salerno, M1
Di Iorgi, N1
Allegri, AME1
Cappa, M1
Maghnie, M1
Loche, S1
Zhou, G1
Du, R1
Willaschek, C1
Meint, S1
Rager, K1
Buchhorn, R1
Lee, HS1
Hwang, JS1
Marino, R1
Chaler, E1
Warman, M1
Ciaccio, M1
Berensztein, E1
Rivarola, MA1
Belgorosky, A1
Nwosu, BU1
Coco, M1
Jones, J1
Barnes, KM1
Yanovski, JA1
Baron, J1
Hoos, MB1
Westerterp, KR1
Kuipers, H1
Schuwirth, L1
Gerver, WJ1
Salvatori, R1
Serpa, MG1
Parmigiani, G1
Britto, AV1
Oliveira, JL1
Oliveira, CR1
Prado, CM1
Farias, CT1
Almeida, JC1
Vicente, TA1
Aguiar-Oliveira, MH1
Butenandt, O1
Dörr, H1
Rüdisser, A1
Joswig, R1
Kühne, H1
Schlagehan, IM1
Lehmann, B1
Hinkel, GK1
Scheuch, DW1
Moreno Romero, F1
Aparicio Palomino, A1
Espinosa Ruiz-Cabal, J1
Cruz Ortega, J1
Requena Guerrero, F1
Cardesa García, JJ1
Rijnberk, A1
van Herpen, H1
Mol, JA1
Rutteman, GR1
Dammacco, F1
Dammacco, A1
Acquafredda, A1
Pesce, S1
Cavallo, T1
Høier, R1
Jensen, AL1
Iversen, L1
Castells, S2
Beaulieu, I1
Torrado, C2
Wisniewski, KE2
Zarny, S1
Gelato, MC1
Wajnrajch, MP1
Gertner, JM1
Huma, Z1
Popovic, J1
Lin, K1
Verlander, PC1
Batish, SD1
Giampietro, PF1
Davis, JG1
New, MI1
Auerbach, AD1
Lanes, R1
Bastian, W1
Lebl, J1
Dvorák, P1
Zizkovský, V1
Gil-Ad, I1
Leibowitch, N1
Josefsberg, Z1
Wasserman, M1
Laron, Z1

Reviews

1 review available for clonidine and Dwarfism, Pituitary

ArticleYear
Growth hormone responses during arginine and clonidine stimulation test: Correlations with patients' auxological and metabolic parameters in a single centre study.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2023, Volume: 68

    Topics: Arginine; Child; Clonidine; Dwarfism, Pituitary; Growth Disorders; Growth Hormone; Human Growth Horm

2023
Growth hormone responses during arginine and clonidine stimulation test: Correlations with patients' auxological and metabolic parameters in a single centre study.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2023, Volume: 68

    Topics: Arginine; Child; Clonidine; Dwarfism, Pituitary; Growth Disorders; Growth Hormone; Human Growth Horm

2023
Growth hormone responses during arginine and clonidine stimulation test: Correlations with patients' auxological and metabolic parameters in a single centre study.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2023, Volume: 68

    Topics: Arginine; Child; Clonidine; Dwarfism, Pituitary; Growth Disorders; Growth Hormone; Human Growth Horm

2023
Growth hormone responses during arginine and clonidine stimulation test: Correlations with patients' auxological and metabolic parameters in a single centre study.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2023, Volume: 68

    Topics: Arginine; Child; Clonidine; Dwarfism, Pituitary; Growth Disorders; Growth Hormone; Human Growth Horm

2023

Trials

1 trial available for clonidine and Dwarfism, Pituitary

ArticleYear
GH response to hypoglycemia and clonidine in the GH-releasing hormone resistance syndrome.
    Journal of endocrinological investigation, 2006, Volume: 29, Issue:9

    Topics: Adolescent; Adult; Blood Glucose; Body Height; Child; Child, Preschool; Clonidine; Dwarfism, Pituita

2006

Other Studies

21 other studies available for clonidine and Dwarfism, Pituitary

ArticleYear
Testing for growth hormone deficiency in children.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2020, Volume: 50

    Topics: Adrenergic alpha-2 Receptor Agonists; Age Determination by Skeleton; Androgens; Arginine; Child; Chi

2020
Diagnosis of Growth Hormone Deficiency in Children: The Efficacy of Glucagon versus Clonidine Stimulation Test.
    Hormone research in paediatrics, 2020, Volume: 93, Issue:7-8

    Topics: Child; Child, Preschool; Clonidine; Dwarfism, Pituitary; Female; Glucagon; Human Growth Hormone; Hum

2020
Reliability of clonidine testing for the diagnosis of growth hormone deficiency in children and adolescents.
    Clinical endocrinology, 2018, Volume: 89, Issue:6

    Topics: Body Mass Index; Child; Clonidine; Dwarfism, Pituitary; Female; Human Growth Hormone; Humans; Insuli

2018
Dynamic Ghrelin and GH serum levels during combined simultaneous arginine clonidine stimulation test in children with dwarfism.
    Italian journal of pediatrics, 2019, Jan-28, Volume: 45, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Arginine; Body Height; Body Weight; Child; Clonidine; Dwarfism

2019
Modified Clonidine Testing for Growth Hormone Stimulation Reveals α2-Adrenoreceptor Sub Sensitivity in Children with Idiopathic Growth Hormone Deficiency.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Adrenergic alpha-2 Receptor Agonists; Blood Pressure; Body Height; Cardiovascular Diseases; Child; C

2015
Influence of body mass index on growth hormone responses to classic provocative tests in children with short stature.
    Neuroendocrinology, 2011, Volume: 93, Issue:4

    Topics: Administration, Oral; Body Mass Index; Child; Clonidine; Dwarfism, Pituitary; Female; Growth Hormone

2011
The serum growth hormone (GH) response to provocative tests is dependent on type of assay in autosomal dominant isolated GH deficiency because of an ARG(183)HIS (R183H) GH-I gene mutation.
    Clinical chemistry, 2003, Volume: 49, Issue:6 Pt 1

    Topics: Child; Clonidine; Dwarfism, Pituitary; Female; Fluoroimmunoassay; Human Growth Hormone; Humans; Immu

2003
Short stature with normal growth hormone stimulation testing: lack of evidence for partial growth hormone deficiency or insensitivity.
    Hormone research, 2004, Volume: 62, Issue:2

    Topics: Adolescent; Adrenergic alpha-Agonists; Arginine; Body Weight; Child; Clonidine; Dwarfism, Pituitary;

2004
Physical activity as measured by accelerometry in children receiving growth hormone.
    Acta paediatrica (Oslo, Norway : 1992), 2004, Volume: 93, Issue:10

    Topics: Arginine; Child; Clonidine; Dwarfism, Pituitary; Female; Growth Hormone; Humans; Male; Motor Activit

2004
[Growth hormone secretion and plasma renin activity in children following administration of clonidine].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1984, Volume: 132, Issue:10

    Topics: Adolescent; Child; Clonidine; Dose-Response Relationship, Drug; Dwarfism, Pituitary; Female; Growth

1984
[Activation of the kallikrein-kinin system by clonidine].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Nov-15, Volume: 39, Issue:22

    Topics: Child; Clonidine; Dose-Response Relationship, Drug; Dwarfism; Dwarfism, Pituitary; Growth Hormone; H

1984
[Oral clonidine test for growth hormone release (author's transl)].
    Anales espanoles de pediatria, 1981, Volume: 14, Issue:4

    Topics: Administration, Oral; Adolescent; Blood Glucose; Blood Pressure; Child; Child, Preschool; Clonidine;

1981
Disturbed release of growth hormone in mature dogs: a comparison with congenital growth hormone deficiency.
    The Veterinary record, 1993, Nov-27, Volume: 133, Issue:22

    Topics: Adrenal Cortex Hormones; Age Factors; Alopecia; Animals; Clonidine; Creatinine; Dexamethasone; Dog D

1993
[Measurement of the spontaneous growth hormone increase in short children. Diagnostic significance and neuroendocrine implications].
    Minerva endocrinologica, 1993, Volume: 18, Issue:3 Suppl 1

    Topics: Adolescent; Body Height; Child; Circadian Rhythm; Clonidine; Dwarfism; Dwarfism, Pituitary; Female;

1993
An improved radioimmunoassay for the determination of canine growth hormone based on commercially available reagents.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1995, Volume: 42, Issue:8

    Topics: Acromegaly; Animals; Antibodies; Clonidine; Dog Diseases; Dogs; Dwarfism, Pituitary; Female; Growth

1995
Hypothalamic versus pituitary dysfunction in Down's syndrome as cause of growth retardation.
    Journal of intellectual disability research : JIDR, 1996, Volume: 40 ( Pt 6)

    Topics: Anthropometry; Child, Preschool; Clonidine; Down Syndrome; Dwarfism, Pituitary; Female; Growth Hormo

1996
Evaluation of growth and hormonal status in patients referred to the International Fanconi Anemia Registry.
    Pediatrics, 2001, Volume: 107, Issue:4

    Topics: Adolescent; Adult; Anthropometry; Body Height; Child; Child, Preschool; Clonidine; Diabetes Mellitus

2001
Hypoglycemia associated with clonidine testing.
    The Journal of pediatrics, 2002, Volume: 140, Issue:5

    Topics: Child; Clonidine; Dwarfism, Pituitary; Humans; Hypoglycemia

2002
Growth hormone deficiency in Down's syndrome children.
    Journal of intellectual disability research : JIDR, 1992, Volume: 36 ( Pt 1)

    Topics: Adolescent; Anthropometry; Child; Child, Preschool; Clonidine; Down Syndrome; Dwarfism, Pituitary; F

1992
[Efficient diagnosis of hypothalamo-hypophyseal nanism: 5 years' experience with the clonidine stimulation test in the diagnosis of growth hormone secretion].
    Ceskoslovenska pediatrie, 1990, Volume: 45, Issue:11

    Topics: Adolescent; Child; Child, Preschool; Clonidine; Dwarfism, Pituitary; Female; Growth Hormone; Humans;

1990
Effect of oral clonidine, insulin-induced hypoglycemia and exercise on plasma GHRH levels in short-stature children.
    Acta endocrinologica, 1990, Volume: 122, Issue:1

    Topics: Administration, Oral; Adolescent; Child; Clonidine; Dwarfism, Pituitary; Exercise; Female; Growth Ho

1990