clonidine has been researched along with Diabetic Nephropathies in 10 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Apraclonidine testing, which is easy to perform and not distressing to the patient, identified PSD in nearly half of DM patients, the degree of mydriasis being correlated to the duration of DM and the presence of DR." | 3.73 | Topical apraclonidine testing discloses pupillary sympathetic denervation in diabetic patients. ( Firat, E; Kansu, T; Kavuncu, S; Koc, F, 2006) |
| "Our study suggests that hypertensive NIDDM patients, particularly patients with nephropathy, frequently suffer from impaired or abolished autoregulation of GFR." | 2.68 | Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients. ( Christensen, PK; Hansen, HP; Parving, HH, 1997) |
| "Experimental early diabetic nephropathy was confirmed by hyperglycemia, changes in physiological parameters, and renal function." | 1.35 | Alpha1B-adrenoceptors mediate adrenergically-induced renal vasoconstrictions in rats with renal impairment. ( Abdullah, NA; Johns, EJ; Khan, MA; Sattar, MA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kwon, HJ | 1 |
| Kim, HY | 1 |
| Christensen, PK | 3 |
| Akram, K | 1 |
| Kønig, KB | 1 |
| Parving, HH | 6 |
| Koc, F | 1 |
| Kansu, T | 1 |
| Kavuncu, S | 1 |
| Firat, E | 1 |
| Khan, MA | 1 |
| Sattar, MA | 1 |
| Abdullah, NA | 1 |
| Johns, EJ | 1 |
| Kastrup, H | 1 |
| Smidt, UM | 2 |
| Andersen, AR | 1 |
| Feldt-Rasmussen, B | 2 |
| Christiansen, JS | 1 |
| Bakris, GL | 1 |
| Smith, A | 1 |
| Hansen, HP | 1 |
| Hommel, EE | 1 |
| Clausen, P | 1 |
| Hommel, E | 1 |
| Mathiesen, E | 1 |
| Edsberg, B | 1 |
| Bahnsen, M | 1 |
| Kastrup, J | 1 |
5 trials available for clonidine and Diabetic Nephropathies
| Article | Year |
|---|---|
Autoregulation of glomerular filtration rate in patients with type 2 diabetes during isradipine therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-Over Studi | 2003 |
Effects of sodium intake on albumin excretion in patients with diabetic nephropathy treated with long-acting calcium antagonists.
Topics: Aged; Albuminuria; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Cross-Over Studies; | 1996 |
Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients.
Topics: Adult; Aged; Blood Glucose; Clonidine; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephr | 1997 |
Impaired autoregulation of the glomerular filtration rate in patients with nondiabetic nephropathies.
Topics: Adolescent; Adult; Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Case-Control Studies; | 1999 |
Acute reduction of arterial blood pressure reduces urinary albumin excretion in type 1 (insulin-dependent) diabetic patients with incipient nephropathy.
Topics: Adult; Albuminuria; Blood Pressure; Clonidine; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Fe | 1986 |
5 other studies available for clonidine and Diabetic Nephropathies
| Article | Year |
|---|---|
A pharmacologic pupillary test in the diagnosis of diabetic autonomic neuropathy.
Topics: Adrenergic alpha-Agonists; Adult; Aged; Clonidine; Diabetic Nephropathies; Diagnosis, Differential; | 2009 |
Topical apraclonidine testing discloses pupillary sympathetic denervation in diabetic patients.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Clonidine; Diabetic Nephropathies; Disease Progr | 2006 |
Alpha1B-adrenoceptors mediate adrenergically-induced renal vasoconstrictions in rats with renal impairment.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Clonidine; Diabetic Nephropathies; I | 2008 |
Impaired autoregulation of glomerular filtration rate in type 1 (insulin-dependent) diabetic patients with nephropathy.
Topics: Adult; Albuminuria; Blood Pressure; Chromium; Chromium Radioisotopes; Clonidine; Diabetes Mellitus, | 1984 |
Reduced transcapillary escape of albumin during acute blood pressure-lowering in type 1 (insulin-dependent) diabetic patients with nephropathy.
Topics: Adult; Blood Glucose; Capillary Permeability; Clonidine; Diabetes Mellitus, Type 1; Diabetic Angiopa | 1985 |