clonidine has been researched along with Diabetes Mellitus, Adult-Onset in 31 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty patients with type II diabetes mellitus and hypertension (WHO stages I and II) participated in a 3-month double-blind cross-over study to evaluate the effects of clonidine (75-300 micrograms daily) on blood pressure, glycemic control and plasma lipoproteins." | 5.06 | Lipoproteins and metabolic control in hypertensive type II diabetics treated with clonidine. ( Ekberg, M; Fridström, P; Lins, LE; Nilsson-Ehle, P; Ursing, D, 1988) |
| "We have recently seen a case of non-insulin-dependent diabetes mellitus with hypertension in which chronic treatment with oral clonidine gave rise to elevation of blood glucose and decreased insulin secretion." | 3.67 | Effect of clonidine on insulin secretion: a case report. ( Higuchi, T; Masaki, Y; Miyai, Y; Ogino, Y; Okada, S; Ota, Z; Sato, K, 1986) |
| "Thirty patients with type 2 diabetes with peripheral neuropathy as assessed by a visual analog scale (VAS) and divided into two groups of 15 patients, treated for up to three months." | 3.30 | Effectiveness of oral clonidine and gabapentin on peripheral neuropathy in diabetic patients in southwestern Iran: a randomized clinical trial. ( Ahmadi, SA; Bagheri, S; Dolatkhah, H; Hassanzadeh, S; Majid Ahmadi, S; Moradishibany, I; Reisi, S, 2023) |
| "Our study suggests that hypertensive NIDDM patients, particularly patients with nephropathy, frequently suffer from impaired or abolished autoregulation of GFR." | 2.68 | Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients. ( Christensen, PK; Hansen, HP; Parving, HH, 1997) |
| "Clonidine was administered to 16 subjects at two dosage levels (0." | 2.67 | Lack of effect of clonidine and pentoxifylline in short-term therapy of diabetic peripheral neuropathy. ( Chomiak, M; Cohen, KL; Lucibello, FE, 1990) |
| "This study aimed to develop a novel type 2 diabetes model designated the HND (Horio-Niki diabetic) mouse, by transferring diabetogenic genes from wild castaneus mice (Mus musculus castaneus) captured in the Philippines into laboratory mice (C57BL/6J:B6)." | 1.33 | The HND mouse, a nonobese model of type 2 diabetes mellitus with impaired insulin secretion. ( Anunciado, RV; Horio, F; Imamura, T; Kobayashi, M; Namikawa, T; Niki, I; Teradaira, S, 2005) |
| "Systemic hypertension is common in individuals with non-insulin-dependent diabetes (NIDD) and, in this population, markedly increases the risk for cardiovascular complications." | 1.31 | NaCl-induced hypertensive rat model of non-insulin-dependent diabetes: role of sympathetic modulation. ( Mozaffari, MS; Patel, C; Schaffer, SW; Warren, BK, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (25.81) | 18.7374 |
| 1990's | 6 (19.35) | 18.2507 |
| 2000's | 11 (35.48) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Hassanzadeh, S | 1 |
| Bagheri, S | 1 |
| Majid Ahmadi, S | 1 |
| Ahmadi, SA | 1 |
| Moradishibany, I | 1 |
| Dolatkhah, H | 1 |
| Reisi, S | 1 |
| Milic, MS | 1 |
| Brkovic, B | 1 |
| Krsljak, E | 1 |
| Stojic, D | 1 |
| Taguchi, K | 4 |
| Hida, M | 1 |
| Matsumoto, T | 5 |
| Kobayashi, T | 5 |
| Barinova, ME | 1 |
| Gould, M | 1 |
| Sellin, JH | 1 |
| Kamata, K | 4 |
| Ishii-Nozawa, R | 1 |
| Mita, M | 1 |
| Shoji, M | 1 |
| Takeuchi, K | 1 |
| Christensen, PK | 4 |
| Akram, K | 1 |
| Kønig, KB | 1 |
| Parving, HH | 4 |
| McAnulty, GR | 1 |
| Hall, GM | 1 |
| Belhoula, M | 1 |
| Ciébiéra, JP | 1 |
| De La Chapelle, A | 1 |
| Boisseau, N | 1 |
| Coeurveille, D | 1 |
| Raucoules-Aimé, M | 1 |
| Yasuhiro, T | 1 |
| Horio, F | 1 |
| Teradaira, S | 1 |
| Imamura, T | 1 |
| Anunciado, RV | 1 |
| Kobayashi, M | 1 |
| Namikawa, T | 1 |
| Niki, I | 1 |
| Takenouchi, Y | 1 |
| Ferlito, S | 2 |
| Del Campo, F | 2 |
| Indelicato, G | 2 |
| Di Vincenzo, S | 2 |
| Fichera, C | 2 |
| La Vignera, A | 2 |
| Okorokov, AN | 1 |
| Geĭman, EV | 1 |
| Schwartz, J | 1 |
| Rosenfeld, V | 1 |
| Hellström, L | 1 |
| Langin, D | 1 |
| Reynisdottir, S | 1 |
| Dauzats, M | 1 |
| Arner, P | 1 |
| Hansen, HP | 1 |
| Giugliano, D | 1 |
| Acampora, R | 1 |
| Marfella, R | 1 |
| La Marca, C | 1 |
| Marfella, M | 1 |
| Nappo, F | 1 |
| D'Onofrio, F | 1 |
| Mozaffari, MS | 1 |
| Patel, C | 1 |
| Warren, BK | 1 |
| Schaffer, SW | 1 |
| Lund, S | 2 |
| Tanaka, K | 1 |
| Cohen, KL | 1 |
| Lucibello, FE | 1 |
| Chomiak, M | 1 |
| Nilsson-Ehle, P | 1 |
| Ekberg, M | 1 |
| Fridström, P | 1 |
| Ursing, D | 1 |
| Lins, LE | 1 |
| Okada, S | 1 |
| Miyai, Y | 1 |
| Sato, K | 1 |
| Masaki, Y | 1 |
| Higuchi, T | 1 |
| Ogino, Y | 1 |
| Ota, Z | 1 |
| Stroev, IuI | 1 |
| Leviashvili, BI | 1 |
| Tan, YM | 1 |
| Croese, J | 1 |
| Wallin, JD | 1 |
| Krane, NK | 1 |
| Bergman, S | 1 |
| Morgan, M | 1 |
10 trials available for clonidine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Effectiveness of oral clonidine and gabapentin on peripheral neuropathy in diabetic patients in southwestern Iran: a randomized clinical trial.
Topics: Amines; Analgesics; Clonidine; Cyclohexanecarboxylic Acids; Diabetes Mellitus, Type 2; Diabetic Neur | 2023 |
Comparison of pulpal anesthesia and cardiovascular parameters with lidocaine with epinephrine and lidocaine with clonidine after maxillary infiltration in type 2 diabetic volunteers.
Topics: Adult; Analgesics; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Clonidine; Cross-Over | 2016 |
Autoregulation of glomerular filtration rate in patients with type 2 diabetes during isradipine therapy.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-Over Studi | 2003 |
Clonidine premedication improves metabolic control in type 2 diabetic patients during ophthalmic surgery.
Topics: Aged; Anti-Anxiety Agents; Blood Glucose; Clonidine; Diabetes Mellitus, Type 2; Drug Administration | 2003 |
Impaired autoregulation of GFR in hypertensive non-insulin dependent diabetic patients.
Topics: Adult; Aged; Blood Glucose; Clonidine; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephr | 1997 |
Hemodynamic and metabolic effects of transdermal clonidine in patients with hypertension and non-insulin-dependent diabetes mellitus.
Topics: Administration, Cutaneous; Adult; Aged; Albuminuria; Blood Glucose; Clonidine; Cross-Over Studies; D | 1998 |
The impact of glycaemic control on autoregulation of glomerular filtration rate in patients with non-insulin dependent diabetes.
Topics: Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Clonidine; Cross-Over Studies; Diabete | 2001 |
Autoregulated glomerular filtration rate during candesartan treatment in hypertensive type 2 diabetic patients.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; | 2001 |
Lack of effect of clonidine and pentoxifylline in short-term therapy of diabetic peripheral neuropathy.
Topics: Clonidine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Double-Blind Method; Drug Evaluation; H | 1990 |
Lipoproteins and metabolic control in hypertensive type II diabetics treated with clonidine.
Topics: Blood Glucose; Clinical Trials as Topic; Clonidine; Diabetes Mellitus, Type 2; Double-Blind Method; | 1988 |
21 other studies available for clonidine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Resveratrol Ameliorates Clonidine-Induced Endothelium-Dependent Relaxation Involving Akt and Endothelial Nitric Oxide Synthase Regulation in Type 2 Diabetic Mice.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Antioxidants; Clonidine; Diabetes Mellitus, Experimen | 2015 |
[Adrenergic reactivity and course of the wound process in diabetes mellitus condition: diagnostic significance and pathogenetic interpretation].
Topics: Adrenergic alpha-Agonists; Adult; Aged; Blood Platelets; Clonidine; Diabetes Mellitus, Type 2; Diabe | 2008 |
Diabetic diarrhea.
Topics: Algorithms; Antidiarrheals; Celiac Disease; Clonidine; Colitis; Diabetes Complications; Diabetes Mel | 2009 |
Inhibitor of G protein-coupled receptor kinase 2 normalizes vascular endothelial function in type 2 diabetic mice by improving β-arrestin 2 translocation and ameliorating Akt/eNOS signal dysfunction.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; Blood Pre | 2012 |
Dysfunction of neurotransmitter modulation system on adrenergic nerves of caudal artery in type 2 diabetic Goto-Kakizaki rats.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic Neurons; A | 2012 |
Suppressed G-protein-coupled receptor kinase 2 activity protects female diabetic-mouse aorta against endothelial dysfunction.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Aorta; Clonidine; Diabetes Mellitus, Experimental; Di | 2013 |
Anaesthesia for the diabetic patient.
Topics: Analgesics; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Blood Glucose; Clonidine; Diabe | 2003 |
Impairment of PI3-K/Akt pathway underlies attenuated endothelial function in aorta of type 2 diabetic mouse model.
Topics: Acetylcholine; Animals; Aorta; Clonidine; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus, E | 2004 |
The HND mouse, a nonobese model of type 2 diabetes mellitus with impaired insulin secretion.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Animals, Wild; Blood Glucose; Clonidine; Crosses, | 2005 |
Possible involvement of Akt activity in endothelial dysfunction in type 2 diabetic mice.
Topics: Adrenomedullin; Animals; Aorta; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Clonidine; | 2008 |
Blood glycerol levels in type-2 diabetics after beta-1-blockade and alpha-2 adrenergic stimulation.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Clonidine; Diabetes Mellitus, T | 1984 |
[Effect of gemiton on carbohydrate metabolic indices].
Topics: Adult; Blood Glucose; Carbohydrates; Carbutamide; Clonidine; Diabetes Mellitus, Type 2; Drug Evaluat | 1984 |
Clonidine for painful diabetic-uremic leg cramps and pruritus--a case report.
Topics: Aged; Clonidine; Diabetes Mellitus, Type 2; Humans; Leg; Male; Muscle Cramp; Pruritus; Uremia | 1993 |
Adipocyte lipolysis in normal weight subjects with obesity among first-degree relatives.
Topics: Adipocytes; Adrenergic beta-Agonists; Adult; Body Mass Index; Bucladesine; Clonidine; Colforsin; Dia | 1996 |
NaCl-induced hypertensive rat model of non-insulin-dependent diabetes: role of sympathetic modulation.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agon | 2000 |
[Altered responses of heart rate, renal sodium handling and plasma growth hormone to clonidine in type II diabetic patients].
Topics: Adult; Aged; Clonidine; Cyclic AMP; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Growth | 1992 |
Effect of clonidine on insulin secretion: a case report.
Topics: Blood Glucose; Clonidine; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Insulin; Insulin | 1986 |
[Use of clofeline in arterial hypertension in diabetes mellitus].
Topics: Adult; Aged; Antihypertensive Agents; Clonidine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 1986 |
Clonidine and diabetic patients with leg pains.
Topics: Clonidine; Diabetes Mellitus, Type 2; Humans; Leg; Male; Middle Aged; Pain | 1986 |
The use of transcutaneous clonidine hydrochloride in the patient with diabetes mellitus and mild hypertension.
Topics: Administration, Topical; Adult; Clonidine; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; | 1985 |
Effect of clonidine on glucose, insulin and glucagon responses to a protein meal in type 2 diabetics.
Topics: Adult; Aged; Blood Glucose; Clonidine; Diabetes Mellitus, Type 2; Dietary Proteins; Female; Food; Gl | 1985 |