clonidine has been researched along with Dermatitis, Contact in 22 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Dermatitis, Contact: A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We compared the effects of transdermal clonidine and oral atenolol on acute exercise performance and on conditioning response to an 8-week program of regular aerobic exercise in young, otherwise healthy subjects with mild hypertension." | 9.06 | Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension. ( Davidman, M; Davies, SF; Graif, JL; Husebye, DG; Iber, C; Maddy, MM; McArthur, CD; O'Connell, MB; Path, MJ, 1989) |
| "We evaluated the safety and efficacy of transdermal clonidine (TC) in 23 patients with essential hypertension over a two-year period." | 9.06 | Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension. ( Horning, JR; McNulty, R; Simmons, JL; Williams, L; Zawada, ET, 1988) |
| "Clonidine in petrolatum, clonidine transdermal device, and its placebo device were assayed for relative irritancy potential (21-day cumulative irritancy assay) and allergic contact dermatitis potential (Draize repeat insult patch test assay)." | 7.67 | Clonidine: irritant and allergic contact dermatitis assays. ( Maibach, H, 1985) |
| "5 mg clonidine (clonidine-TTS) was investigated in 21 patients with essential hypertension over a period of 10 weeks." | 7.66 | [Clonidine transdermal therapeutic system in essential hypertension: effect and tolerance]. ( Baumgart, P; Boerlin, HJ; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W; Walger, P; Wehling, M, 1983) |
| " However, chronic use of clonidine-TTS was accompanied by a high frequency of contact dermatitis (type IV allergy) in nearly half of our patients (n = 15, 47%)." | 5.27 | Transdermal clonidine application: long-term results in essential hypertension. ( Foerster, E; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W, 1984) |
| "We compared the effects of transdermal clonidine and oral atenolol on acute exercise performance and on conditioning response to an 8-week program of regular aerobic exercise in young, otherwise healthy subjects with mild hypertension." | 5.06 | Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension. ( Davidman, M; Davies, SF; Graif, JL; Husebye, DG; Iber, C; Maddy, MM; McArthur, CD; O'Connell, MB; Path, MJ, 1989) |
| "We evaluated the safety and efficacy of transdermal clonidine (TC) in 23 patients with essential hypertension over a two-year period." | 5.06 | Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension. ( Horning, JR; McNulty, R; Simmons, JL; Williams, L; Zawada, ET, 1988) |
| "The effectiveness of transdermally administered clonidine using Catapres-TTS patches applied once a week was assessed in the control of mild to moderate hypertension by 16 general practitioners in 135 subjects." | 5.06 | A community-based trial of transdermal antihypertensive therapy with clonidine (Catapres-TTS). ( Kellaway, GS; Lubbe, WF, 1986) |
| "During clinical trials, a clonidine transdermal device has been found to induce clonidine-specific allergic contact dermatitis in up to 25% of patients during a treatment period of 1 year." | 3.68 | Low allergenicity of clonidine impedes studies of sensitization mechanisms in guinea pig models. ( Bruynzeel, DP; de Groot, J; Goeptar, AR; Lang, M; Oostendorp, RA; Scheper, RJ; van Tol, RG; von Blomberg, BM, 1990) |
| "In the present study, immunopharmacological effects of clonidine-TTS on allergic contact dermatitis (ACD) to non-related, established contact sensitizers were investigated in guinea pigs." | 3.67 | Suppressive effects of transdermal clonidine administration on contact hypersensitivity reactions in guinea pigs. ( de Groot, J; Goeptar, AR; Lang, M; Scheper, RJ; van Tol, RG, 1988) |
| " The toxic contact reaction to croton oil (nonspecific cutaneous inflammation) was not affected." | 3.67 | Effects of clonidine on the dermal inflammatory cell response of experimental toxic and allergic contact reactions and intradermal hypersensitivity. ( Anderson, CD; Andersson, RG; Lindgren, BR, 1987) |
| "The safety of oral clonidine substitution in 29 patients with confirmed localized allergic contact dermatitis due to transdermal clonidine treatment was evaluated." | 3.67 | Oral substitution in patients sensitized by transdermal clonidine treatment. ( Maibach, HI, 1987) |
| "Twenty patients aged 60-74 years entered a study on the effect of transdermal clonidine (Catapres-TTS) as monotherapy for mild hypertension [diastolic blood pressure (DBP) 90-104 mmHg]." | 3.67 | Transdermal clonidine therapy in elderly mild hypertensives: effects on blood pressure, plasma norepinephrine and fasting plasma glucose. ( Kelley, S; Klein, C; Metz, S; Morton, N, 1985) |
| "Clonidine in petrolatum, clonidine transdermal device, and its placebo device were assayed for relative irritancy potential (21-day cumulative irritancy assay) and allergic contact dermatitis potential (Draize repeat insult patch test assay)." | 3.67 | Clonidine: irritant and allergic contact dermatitis assays. ( Maibach, H, 1985) |
| "5 mg clonidine (clonidine-TTS) was investigated in 21 patients with essential hypertension over a period of 10 weeks." | 3.66 | [Clonidine transdermal therapeutic system in essential hypertension: effect and tolerance]. ( Baumgart, P; Boerlin, HJ; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W; Walger, P; Wehling, M, 1983) |
| " However, chronic use of clonidine-TTS was accompanied by a high frequency of contact dermatitis (type IV allergy) in nearly half of our patients (n = 15, 47%)." | 1.27 | Transdermal clonidine application: long-term results in essential hypertension. ( Foerster, E; Groth, H; Knüsel, J; Siegenthaler, W; Vetter, H; Vetter, W, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (77.27) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Solinski, HJ | 1 |
| Dranchak, P | 1 |
| Oliphant, E | 1 |
| Gu, X | 1 |
| Earnest, TW | 1 |
| Braisted, J | 1 |
| Inglese, J | 1 |
| Hoon, MA | 1 |
| Boekhorst, JC | 1 |
| Groth, H | 2 |
| Vetter, H | 2 |
| Knüsel, J | 2 |
| Foerster, E | 1 |
| Siegenthaler, W | 2 |
| Vetter, W | 2 |
| Boerlin, HJ | 1 |
| Walger, P | 1 |
| Baumgart, P | 1 |
| Wehling, M | 1 |
| van Ketel, WG | 1 |
| McChesney, JA | 1 |
| Hogan, DJ | 1 |
| Maibach, HI | 2 |
| Scheper, RJ | 2 |
| von Blomberg, BM | 1 |
| de Groot, J | 2 |
| Goeptar, AR | 2 |
| Lang, M | 2 |
| Oostendorp, RA | 1 |
| Bruynzeel, DP | 1 |
| van Tol, RG | 2 |
| Robinson, MK | 1 |
| Sozeri, TJ | 1 |
| Jeunemaitre, X | 1 |
| Ged, E | 1 |
| Ducrocq, MB | 1 |
| Alhenc-Gelas, F | 1 |
| Corvol, P | 1 |
| Menard, J | 1 |
| Holdiness, MR | 1 |
| Davies, SF | 1 |
| Graif, JL | 1 |
| Husebye, DG | 1 |
| Maddy, MM | 1 |
| McArthur, CD | 1 |
| Path, MJ | 1 |
| O'Connell, MB | 1 |
| Iber, C | 1 |
| Davidman, M | 1 |
| Horning, JR | 1 |
| Zawada, ET | 1 |
| Simmons, JL | 1 |
| Williams, L | 1 |
| McNulty, R | 1 |
| Kellaway, GS | 1 |
| Lubbe, WF | 1 |
| Anderson, CD | 1 |
| Lindgren, BR | 1 |
| Andersson, RG | 1 |
| White, TM | 1 |
| Guidry, JR | 1 |
| Gosse, P | 1 |
| Wicker, P | 1 |
| Roudaut, R | 1 |
| Danays, T | 1 |
| Dallocchio, M | 1 |
| Klein, C | 1 |
| Morton, N | 1 |
| Kelley, S | 1 |
| Metz, S | 1 |
| Maibach, H | 1 |
2 reviews available for clonidine and Dermatitis, Contact
| Article | Year |
|---|---|
Adverse dermatologic reactions to transdermal drug delivery systems.
Topics: Administration, Cutaneous; Clonidine; Dermatitis, Contact; Estradiol; Forecasting; Humans; Nitroglyc | 1990 |
A review of contact dermatitis associated with transdermal therapeutic systems.
Topics: Administration, Cutaneous; Administration, Oral; Clonidine; Dermatitis, Contact; Estradiol; Humans; | 1989 |
4 trials available for clonidine and Dermatitis, Contact
| Article | Year |
|---|---|
Effects of transdermal clonidine in young and elderly patients with mild hypertension: evaluation by three noninvasive methods of blood pressure measurement.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Blood Pressure Determination; Clonidine; Der | 1987 |
Comparative effects of transdermal clonidine and oral atenolol on acute exercise performance and response to aerobic conditioning in subjects with hypertension.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Atenolol; Clonidine; Dermatitis, Contact; Do | 1989 |
Efficacy and safety of two-year therapy with transdermal clonidine for essential hypertension.
Topics: Administration, Cutaneous; Chlorthalidone; Clinical Trials as Topic; Clonidine; Dermatitis, Contact; | 1988 |
A community-based trial of transdermal antihypertensive therapy with clonidine (Catapres-TTS).
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Clonidine; Dermati | 1986 |
16 other studies available for clonidine and Dermatitis, Contact
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S | 2019 |
Allergic skin reactions to transdermal clonidine.
Topics: Clonidine; Dermatitis, Contact; Humans; Skin | 1983 |
Allergic contact dermatitis with transdermal clonidine.
Topics: Clonidine; Dermatitis, Contact; Humans; Methods; Skin Absorption | 1983 |
Transdermal clonidine application: long-term results in essential hypertension.
Topics: Administration, Topical; Adult; Clonidine; Dermatitis, Contact; Female; Humans; Hypertension; Male; | 1984 |
[Clonidine transdermal therapeutic system in essential hypertension: effect and tolerance].
Topics: Adult; Body Weight; Clonidine; Dermatitis, Contact; Drug Tolerance; Female; Heart Rate; Humans; Hydr | 1983 |
[Contact allergy to clonidine-TTS].
Topics: Administration, Topical; Clonidine; Dermatitis, Contact; Humans | 1984 |
Preventing the contact dermatitis caused by a transdermal clonidine patch.
Topics: Administration, Cutaneous; Aerosols; Beclomethasone; Clonidine; Dermatitis, Contact; Humans | 1991 |
Low allergenicity of clonidine impedes studies of sensitization mechanisms in guinea pig models.
Topics: Administration, Cutaneous; Animals; Clonidine; Cyclophosphamide; Dermatitis, Contact; Disease Models | 1990 |
Immunosuppressive effects of clonidine on the induction of contact sensitization in the balb/c mouse.
Topics: Animals; Cell Division; Clonidine; Dermatitis, Contact; Ear; Epidermis; Female; Immunosuppressive Ag | 1990 |
Suppressive effects of transdermal clonidine administration on contact hypersensitivity reactions in guinea pigs.
Topics: Administration, Cutaneous; Animals; Blood Pressure; Clonidine; Dermatitis, Contact; Dinitrochloroben | 1988 |
Effects of clonidine on the dermal inflammatory cell response of experimental toxic and allergic contact reactions and intradermal hypersensitivity.
Topics: Animals; Cell Movement; Clonidine; Croton Oil; Dermatitis, Contact; Drug Hypersensitivity; Female; G | 1987 |
Rebound hypertension associated with transdermal clonidine and contact dermatitis.
Topics: Administration, Topical; Aged; Clonidine; Dermatitis, Contact; Female; Humans; Hypertension; Recurre | 1986 |
Oral substitution in patients sensitized by transdermal clonidine treatment.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Clonidine; Dermatitis, Contact; Female | 1987 |
Treatment of hypertension by a new transdermal form of clonidine.
Topics: Adhesiveness; Administration, Oral; Administration, Topical; Aged; Clonidine; Dermatitis, Contact; D | 1985 |
Transdermal clonidine therapy in elderly mild hypertensives: effects on blood pressure, plasma norepinephrine and fasting plasma glucose.
Topics: Administration, Topical; Aged; Blood Glucose; Blood Pressure; Clonidine; Dermatitis, Contact; Female | 1985 |
Clonidine: irritant and allergic contact dermatitis assays.
Topics: Administration, Topical; Adult; Aged; Clonidine; Dermatitis, Contact; Female; Humans; Male; Middle A | 1985 |