clonidine has been researched along with Delirium of Mixed Origin in 20 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Excerpt | Relevance | Reference |
---|---|---|
"Postoperative infusion of dexmedetomidine provides a feasible option for postoperative control of delirium after CABG in adult patients." | 9.34 | A randomized control trial comparing prophylactic dexmedetomidine versus clonidine on rates and duration of delirium in older adult patients undergoing coronary artery bypass grafting. ( Ali, I; Shokri, H, 2020) |
"The aim of this double-blinded randomised placebo-controlled trial was to investigate the efficacy of clonidine for delirium in medical inpatients greater than 65 years." | 9.30 | The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial. ( Hov, KR; MacLullich, AMJ; Neerland, BE; Qvigstad, E; Skovlund, E; Undseth, Ø; Wyller, TB; Wyller, VBB, 2019) |
"The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is a randomised, placebo-controlled, double-blinded, parallel group study with 4-month prospective follow-up." | 9.20 | The protocol of the Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial. ( Bruun Wyller, T; Bruun Wyller, V; Hov, KR; MacLullich, AM; Neerland, BE; Qvigstad, E; Skovlund, E, 2015) |
"A comprehensive literature search was conducted to identify clinical trials that observed the effect of midazolam and clonidine on preventing EA in children after their emergence from sevoflurane anesthesia." | 8.89 | Prophylactic midazolam and clonidine for emergence from agitation in children after emergence from sevoflurane anesthesia: a meta-analysis. ( Li, J; Wang, Y; Zhang, C; Zhao, D, 2013) |
"Haloperidol and clonidine are commonly used to treat agitation in delirious intensive care unit (ICU) patients, but it is unclear whether these agents may shorten the duration of delirium." | 8.02 | Haloperidol, clonidine and resolution of delirium in critically ill patients: a prospective cohort study. ( Dijkstra-Kersten, SMA; Slooter, AJC; Smit, L; van der Jagt, M; Zaal, IJ, 2021) |
"Clonidine-induced delirium has rarely been reported." | 7.73 | Clonidine-induced delirium. ( Delaney, J; Doddamani, S; Ostfeld, R; Spevack, D, 2006) |
"Postoperative infusion of dexmedetomidine provides a feasible option for postoperative control of delirium after CABG in adult patients." | 5.34 | A randomized control trial comparing prophylactic dexmedetomidine versus clonidine on rates and duration of delirium in older adult patients undergoing coronary artery bypass grafting. ( Ali, I; Shokri, H, 2020) |
"The aim of this double-blinded randomised placebo-controlled trial was to investigate the efficacy of clonidine for delirium in medical inpatients greater than 65 years." | 5.30 | The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial. ( Hov, KR; MacLullich, AMJ; Neerland, BE; Qvigstad, E; Skovlund, E; Undseth, Ø; Wyller, TB; Wyller, VBB, 2019) |
"The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is a randomised, placebo-controlled, double-blinded, parallel group study with 4-month prospective follow-up." | 5.20 | The protocol of the Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial. ( Bruun Wyller, T; Bruun Wyller, V; Hov, KR; MacLullich, AM; Neerland, BE; Qvigstad, E; Skovlund, E, 2015) |
"A comprehensive literature search was conducted to identify clinical trials that observed the effect of midazolam and clonidine on preventing EA in children after their emergence from sevoflurane anesthesia." | 4.89 | Prophylactic midazolam and clonidine for emergence from agitation in children after emergence from sevoflurane anesthesia: a meta-analysis. ( Li, J; Wang, Y; Zhang, C; Zhao, D, 2013) |
"Haloperidol and clonidine are commonly used to treat agitation in delirious intensive care unit (ICU) patients, but it is unclear whether these agents may shorten the duration of delirium." | 4.02 | Haloperidol, clonidine and resolution of delirium in critically ill patients: a prospective cohort study. ( Dijkstra-Kersten, SMA; Slooter, AJC; Smit, L; van der Jagt, M; Zaal, IJ, 2021) |
" In this report, we describe a 15-year-old adolescent girl who experienced continued delirium 5 days after an overdose of quetiapine, trazodone, and clonidine." | 3.76 | Prolonged delirium after quetiapine overdose. ( Pedapati, EV; Rhyee, SH; Thompson, J, 2010) |
"Clonidine-induced delirium has rarely been reported." | 3.73 | Clonidine-induced delirium. ( Delaney, J; Doddamani, S; Ostfeld, R; Spevack, D, 2006) |
"A patient who underwent cardiopulmonary bypass developed a syndrome of malignant hypertension with agitated delirium, unresponsive to antihypertensive agents, following abrupt withdrawal of clonidine." | 3.65 | Acute clonidine withdrawal syndrome following open-heart operation. ( Brenner, WI; Lieberman, AN, 1977) |
"Clonidine has similar pharmacological properties and can be administered both parenterally and orally." | 3.11 | Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial. ( Busund, R; Haaverstad, R; Helbostad, JL; Landsverk, SA; Martinaityte, I; Neerland, BE; Norum, HM; Ræder, J; Selbaek, G; Simpson, MR; Skaar, E; Skjærvold, NK; Skovlund, E; Slooter, AJ; Svendsen, ØS; Tønnessen, T; Wahba, A; Wyller, TB; Zetterberg, H, 2022) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (20.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (10.00) | 29.6817 |
2010's | 10 (50.00) | 24.3611 |
2020's | 4 (20.00) | 2.80 |
Authors | Studies |
---|---|
Neerland, BE | 3 |
Busund, R | 1 |
Haaverstad, R | 1 |
Helbostad, JL | 1 |
Landsverk, SA | 1 |
Martinaityte, I | 1 |
Norum, HM | 1 |
Ræder, J | 1 |
Selbaek, G | 1 |
Simpson, MR | 1 |
Skaar, E | 1 |
Skjærvold, NK | 1 |
Skovlund, E | 3 |
Slooter, AJ | 1 |
Svendsen, ØS | 1 |
Tønnessen, T | 1 |
Wahba, A | 1 |
Zetterberg, H | 1 |
Wyller, TB | 2 |
Shokri, H | 1 |
Ali, I | 1 |
Bastos, AS | 1 |
Beccaria, LM | 1 |
Silva, DCD | 1 |
Barbosa, TP | 1 |
Smit, L | 1 |
Dijkstra-Kersten, SMA | 1 |
Zaal, IJ | 1 |
van der Jagt, M | 1 |
Slooter, AJC | 1 |
Neubert, A | 1 |
Baarslag, MA | 1 |
Dijk, MV | 1 |
Rosmalen, JV | 1 |
Standing, JF | 1 |
Sheng, Y | 1 |
Rascher, W | 1 |
Roberts, D | 1 |
Winslade, J | 1 |
Rawcliffe, L | 1 |
Hanning, SM | 1 |
Metsvaht, T | 1 |
Giannuzzi, V | 1 |
Larsson, P | 1 |
Pokorná, P | 1 |
Simonetti, A | 1 |
Tibboel, D | 1 |
Hov, KR | 2 |
Undseth, Ø | 1 |
Wyller, VBB | 1 |
MacLullich, AMJ | 1 |
Qvigstad, E | 2 |
Zhang, C | 1 |
Li, J | 1 |
Zhao, D | 1 |
Wang, Y | 1 |
Blackburn, L | 1 |
Ottaway, K | 1 |
Anderson, BJ | 1 |
Pickard, A | 1 |
Davies, P | 1 |
Birnie, K | 1 |
Beringer, R | 1 |
Bruun Wyller, V | 1 |
MacLullich, AM | 1 |
Bruun Wyller, T | 1 |
Keating, GM | 1 |
Rubino, AS | 1 |
Onorati, F | 1 |
Caroleo, S | 1 |
Galato, E | 1 |
Nucera, S | 1 |
Amantea, B | 1 |
Santini, F | 1 |
Renzulli, A | 1 |
Rhyee, SH | 1 |
Pedapati, EV | 1 |
Thompson, J | 1 |
Patil, SK | 1 |
Anitescu, M | 1 |
Rosenberg, MH | 1 |
Deerfield, LJ | 1 |
Baruch, EM | 1 |
Delaney, J | 1 |
Spevack, D | 1 |
Doddamani, S | 1 |
Ostfeld, R | 1 |
Hoffmann, WF | 1 |
Ladogana, L | 1 |
Allen, RM | 1 |
Flemenbaum, A | 1 |
Brenner, WI | 1 |
Lieberman, AN | 1 |
Hughes, PL | 1 |
Morse, RM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Alpha 2 Adrenergic Receptor Agonists for the Prevention of Delirium and Cognitive Decline After Open Heart Surgery (ALPHA2PREVENT): Randomised Controlled Trial.[NCT05029050] | Phase 4 | 900 participants (Anticipated) | Interventional | 2022-01-17 | Recruiting | ||
Phase 1B Study of Sublingual Dexmedetomidine, an Alpha 2 Adrenergic Agonist, for Treating Opioid Withdrawal[NCT05712707] | Phase 1/Phase 2 | 160 participants (Anticipated) | Interventional | 2023-02-28 | Recruiting | ||
A Double Blind, Randomised, Multicentre, Active Controlled, Parallel-group, Phase III Trial to Evaluate the Efficacy, Safety and Pharmacokinetics of Intravenous Clonidine (Hydrochloride) Compared to Midazolam for Sedation in Children From Birth to Less Th[NCT02509273] | Phase 3 | 28 participants (Actual) | Interventional | 2016-05-31 | Terminated (stopped due to lack of recruitment) | ||
A Randomized, Double-Blinded, Placebo Controlled Trial Using Single Dose Dexmedetomidine In The Treatment Of Pain In Patients Undergoing Cleft Palate Repair[NCT02915042] | Phase 4 | 0 participants (Actual) | Interventional | 2017-12-31 | Withdrawn (stopped due to Recruitment concerns) | ||
Does Intraoperative Clonidine Reduce Post Operative Agitation in Children Anaesthetised With Sevoflurane? A RCT Including Pharmacokinetic Investigation.[NCT02361476] | Phase 4 | 379 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
Effect of Single-dose Dexmedetomidine on Emergence Agitation and Postoperative Behavior Changes After Sevoflurane Anesthesia in Children[NCT03596775] | Early Phase 1 | 96 participants (Anticipated) | Interventional | 2018-09-01 | Not yet recruiting | ||
The Oslo Study of Clonidine in Elderly Patients With Delirium[NCT01956604] | Phase 2 | 20 participants (Actual) | Interventional | 2014-04-10 | Terminated (stopped due to The inclusion rate was too low, due to the exclusion criteria.) | ||
Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction: a Double-Blind, Multicenter, Randomized, Placebo-Controlled Clinical Trial[NCT04912518] | 250 participants (Anticipated) | Interventional | 2021-05-27 | Recruiting | |||
Effect of Mini-dose Dexmedetomidine-Esketamine Infusion on Sleep Quality in Older Patients Undergoing Knee or Hip Replacement Surgery: A Multicenter Randomized Controlled Trial[NCT05950646] | Phase 4 | 154 participants (Anticipated) | Interventional | 2023-11-01 | Recruiting | ||
Effect of Low-dose Dexmedetomidine on Postoperative Delirium in Patients After Cardiac Surgery: A Multicenter, Double-blinded, Randomized Controlled Trial[NCT03624595] | 502 participants (Anticipated) | Interventional | 2019-04-16 | Active, not recruiting | |||
Combined Use of Dexmedetomidine and Hydrocortisone to Prevent New Onset Atrial Fibrillation After Coronary Artery Bypass Grafting Surgery[NCT05674253] | Early Phase 1 | 248 participants (Anticipated) | Interventional | 2022-12-25 | Recruiting | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Amount used (NCT02361476)
Timeframe: Recorded during the stay in the postoperative recovery room
Intervention | mg morphine equivalents (Mean) |
---|---|
Intervention | 0.46 |
Placebo | 0.7 |
Time to administration (NCT02361476)
Timeframe: recovery room
Intervention | MEDIAN time (min) to administration (Median) |
---|---|
Intervention | 105 |
Placebo | 60 |
"Pain score used:~FLACC score = Face, Legs, Activity, Cry, Consolability Score ranges from 0 to 10 (severity increases with increasing score) Pain is FLACC score more than 3" (NCT02361476)
Timeframe: recovery room - hours
Intervention | Pain Score (Mean) |
---|---|
Intervention | 1.57 |
Placebo | 2.45 |
Measured by Watchae Scale (score 1-4), scores 1-2 = no agitation and scores 3-4 = agitated (NCT02361476)
Timeframe: 1 day
Intervention | participants with agitation (Number) |
---|---|
Intervention | 46 |
Placebo | 86 |
(NCT02361476)
Timeframe: from intervention to discharge from the recovery room
Intervention | participants (Number) | ||
---|---|---|---|
adverse events | serious adverse events | Treated for low blood pressure | |
Intervention | 0 | 2 | 0 |
Placebo | 5 | 2 | 0 |
3 reviews available for clonidine and Delirium of Mixed Origin
Article | Year |
---|---|
Prophylactic midazolam and clonidine for emergence from agitation in children after emergence from sevoflurane anesthesia: a meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2013 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Systematic review and meta-analysis of the effect of intraoperative α₂-adrenergic agonists on postoperative behaviour in children.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Anesthesia Recovery Period; Anest | 2014 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Topics: Clonidine; Conscious Sedation; Critical Care; Delirium; Dexmedetomidine; Drug Interactions; Humans; | 2015 |
6 trials available for clonidine and Delirium of Mixed Origin
Article | Year |
---|---|
Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Cardiac Surgical Procedures; Clonidine; Cognitive Dysfun | 2022 |
A randomized control trial comparing prophylactic dexmedetomidine versus clonidine on rates and duration of delirium in older adult patients undergoing coronary artery bypass grafting.
Topics: Aged; Clonidine; Coronary Artery Bypass; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; | 2020 |
The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: study protocol for a multicentre randomised controlled trial.
Topics: Adolescent; Analgesics, Opioid; Child; Child Development; Child, Preschool; Clonidine; Delirium; Hum | 2017 |
The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Aged, 80 and over; Clonidine; Delirium; Double-Blind Met | 2019 |
The protocol of the Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial.
Topics: Adrenergic alpha-2 Receptor Agonists; Aged; Clonidine; Cognition; Delirium; Double-Blind Method; Fem | 2015 |
Impact of clonidine administration on delirium and related respiratory weaning after surgical correction of acute type-A aortic dissection: results of a pilot study.
Topics: Acute Disease; Adrenergic alpha-Agonists; Aged; Aortic Aneurysm; Aortic Dissection; Central Nervous | 2010 |
11 other studies available for clonidine and Delirium of Mixed Origin
Article | Year |
---|---|
Prevalence of delirium in intensive care patients and association with sedoanalgesia, severity and mortality.
Topics: Analgesics; Chi-Square Distribution; Clonidine; Critical Care; Cross-Sectional Studies; Delirium; Fe | 2020 |
Haloperidol, clonidine and resolution of delirium in critically ill patients: a prospective cohort study.
Topics: Clonidine; Cohort Studies; Critical Illness; Delirium; Haloperidol; Humans; Intensive Care Units; Pr | 2021 |
Night terrors and emergence delirium.
Topics: Adrenergic alpha-Agonists; Anesthesia; Anesthesia Recovery Period; Child; Child, Preschool; Clonidin | 2014 |
Prolonged delirium after quetiapine overdose.
Topics: Adolescent; Antipsychotic Agents; Cholinergic Antagonists; Clonidine; Cytochrome P-450 CYP3A; Deliri | 2010 |
Opioid-free perioperative analgesia for hemicolectomy in a patient with opioid-induced delirium: a case report and review of the analgesic efficacy of the alpha-2 agonist agents.
Topics: Abdominal Abscess; Adrenergic alpha-2 Receptor Agonists; Analgesia, Epidural; Analgesics, Non-Narcot | 2012 |
Two cases of severe gamma-hydroxybutyrate withdrawal delirium on a psychiatric unit: recommendations for management.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Clonazepam; Clonidine; Delirium; Hospitalization; H | 2003 |
Clonidine-induced delirium.
Topics: Adrenergic alpha-Agonists; Clonidine; Delirium; Diagnosis, Differential; Follow-Up Studies; Humans; | 2006 |
Delirium secondary to clonidine therapy.
Topics: Adult; Clonidine; Delirium; Humans; Hypertension; Male | 1981 |
Delirium associated with combined fluphenazine-clonidine therapy.
Topics: Adult; Clonidine; Delirium; Drug Therapy, Combination; Fluphenazine; Humans; Hypertension; Male; Psy | 1979 |
Acute clonidine withdrawal syndrome following open-heart operation.
Topics: Cardiopulmonary Bypass; Clonidine; Delirium; Female; Humans; Hypertension, Malignant; Middle Aged; S | 1977 |
Use of clonidine in a mixed-drug detoxification regimen: possibility of masking of clinical signs of sedative withdrawal.
Topics: Anti-Anxiety Agents; Barbiturates; Benzodiazepines; Clonidine; Delirium; Diagnosis, Differential; Hu | 1985 |