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clonidine and Decerebrate Posturing

clonidine has been researched along with Decerebrate Posturing in 101 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes."5.29Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996)
"1 mg kg(-1), displaced the dose-response curve approximately six-fold to the right."1.33Postjunctional alpha1-adrenoceptors in the vasculature of the pithed mouse are of the alpha1A-subtype. ( Ibarra, M; López-Guerrero, JJ; Villalobos-Molina, R, 2005)
" After an acute, 1-day spinalization, there was no change in the antinociceptive dose-response function to clonidine, relative to intact rats."1.31Spinal transection increases the potency of clonidine on the tail-flick and hindlimb flexion reflexes. ( Advokat, C, 2002)
"Heart failure is associated with increased sympathetic nerve activity."1.30Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure. ( Edvinsson, L; Feng, Q; Hedner, T; Lu, X; Sun, X, 1999)
"Hypertension is often present in the diabetic individual and it is known to aggravate the vascular complications associated with diabetes."1.29Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996)
" doses of efaroxan (mumol/kg) producing 2-fold shifts in dose-response curves for UK-14,304 at prejunctional cardiac alpha 2-adrenoceptors and postjunctional vascular alpha 2-adrenoceptors, and for cirazoline at postjunctional vascular alpha 1-adrenoceptors, were 0."1.28Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat. ( Berridge, TL; Doxey, JC; Roach, AG; Smith, CF, 1992)
"Treatment with captopril was found to attenuate pressor responses produced by the administration of either alpha 1- or alpha 2-adrenoceptor agonists, resulting in the displacement to the right of the agonist dose-response curves and significantly increasing the calculated ED50 values."1.28The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation. ( Tabrizchi, R; Triggle, CR, 1992)
" The ED50 value for the dose-response curves to B-HT 920 and St587 were found to be significantly increased after the administration of staurosporine."1.28Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine. ( Tabrizchi, R; Triggle, CR, 1991)
"Clonidine was used as an alpha 2-adrenoceptor agonist, and yohimbine and rauwolscine were used as antagonists."1.28Peripheral presynaptic and central effects of clonidine, yohimbine and rauwolscine on the sympathetic nervous system in rabbits. ( Hedler, L; Starke, K; Szabo, B, 1989)
"In pithed rats two recently-introduced beta-blockers, nipradilol and arotinolol, as well as labetalol shifted the pressor dose-response curve for phenylephrine to the right."1.27Alpha-blockade and vasodilatation induced by nipradilol, arotinolol and labetalol in pithed rats. ( Chin, WP; Imai, S; Nakagawa, Y; Nakahara, H, 1985)
" The loss of the righting reflex induced by clonidine in the chicken was prevented by (+/-) and (+) S9871, as shown by a shift of the dose-response curve to clonidine to the right by both agents; on the contrary, (-) S9871 potentiated the sedation induced by clonidine."1.27Antagonistic effects of S9871 or (imidazolinyl-2)-2-dihydro 2,3 benzofurane and its stereoisomers on some central and peripheral actions of alpha 2-agonists. ( Joly, G; Mouillé, P; Schmitt, H, 1985)
" In addition, L-654,284 had better (5-6 times) oral bioavailability than RX 781094 or WY 26703."1.27L-654,284 a new potent and selective alpha 2-adrenoceptor antagonist. ( Baldwin, JJ; Clineschmidt, BV; Huff, JR; Lotti, VJ; Martin, GE; Pettibone, DJ; Randall, WC; Vacca, J, 1986)
"Rilmenidine (S 3341) is a new alpha 2 agonist, with antihypertensive properties."1.27Cardiovascular and central nervous system effects of rilmenidine (S 3341) in rats. ( Beau, B; Delbarre, G; Koenig-Berard, E; Labrid, C; Lhoste, F; Tierney, C, 1988)
"Naloxone was significantly more effective in spinalized rabbits whereas idazoxan had a much larger effect in non-spinalized animals."1.27Adrenergic and opioidergic modulation of a spinal reflex in the decerebrated rabbit. ( Clarke, RW; Ford, TW; Taylor, JS, 1988)
"Clonidine may prove to be a useful therapeutic adjunct in the treatment of spasticity."1.27Effect of clonidine on motoneuron excitability in spinalized rats. ( Bedard, PJ; Tremblay, LE, 1986)
" These data argue against desensitisation of peripheral presynaptic alpha 2-adrenoceptors by chronic administration of alpha 2-adrenoceptor agonist."1.27Chronic clonidine treatment produces desensitisation of post- but not presynaptic alpha 2-adrenoceptors. ( Finberg, JP; Kopin, IJ, 1987)
"When clonidine was given 1-3 months following the transection, at a time when the spinal cats had a stable and regular locomotor performance, the step length increased markedly, especially at low speeds."1.27The effects of clonidine and yohimbine on locomotion and cutaneous reflexes in the adult chronic spinal cat. ( Barbeau, H; Julien, C; Rossignol, S, 1987)
" In some of the pithed rats dose-response curves were constructed to exogenously administered noradrenaline (NA) and sympathetic nerve stimulation (SNS) through the pithing rod before and after the administration of an inhibitor of the neuronal uptake mechanism (desipramine, DMI, 0."1.27A low dietary sodium intake reduces neuronal noradrenaline release and the blood pressure in spontaneously hypertensive rats. ( Dahlöf, C; Gradin, K; Persson, B, 1986)
"Urapidil is a novel antihypertensive agent, chemically related to uracil."1.27Cardiovascular effects and interaction with adrenoceptors of urapidil. ( Beckeringh, JJ; de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B, 1985)
" The dose-response curve to guanfacine for increase in blood pressure was shifted in a parallel fashion to the right by 1 mg/kg of yohimbine, an alpha 2-antagonist and by 1 mg/kg of phentolamine, a nonselective alpha 1- and alpha 2-antagonist."1.26[Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine]. ( Chin, W; Imai, S; Nakagawa, Y, 1982)
" The vasodepressor effect of guanfacine was clearly dose-dependent, and was more marked when the initial level of the blood pressure was high, while that of clonidine was dose-dependent, only within a limited dosage range."1.26[Antihypertensive effect of guanfacine in rats]. ( Hamamura, M; Hashimoto, T; Imai, S; Kumada, M; Mitomi, A; Nakagawa, Y; Sakurai, H; Takeda, K, 1981)
"Pretreatment with piperoxane (10 mg/kg) antagonized this effect but pretreatment with phentolamine (10 mg/kg) did not."1.26Effects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats. ( Aghajanian, GK; Cedarbaum, JM; Davis, M; Gendelman, DS, 1977)
"Clonidine 100 mug/kg was given to conscious and to decerebrated rats."1.25Effects of pentobarbitone and decerebration on the clonidine-induced circulatory changes. ( Trolin, G, 1975)

Research

Studies (101)

TimeframeStudies, this research(%)All Research%
pre-199058 (57.43)18.7374
1990's34 (33.66)18.2507
2000's9 (8.91)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Monroy-Ordoñez, EB1
Villalón, CM2
Cobos-Puc, LE1
Márquez-Conde, JA1
Sánchez-López, A1
Centurión, D2
Bouyer, LJ1
Rossignol, S5
Li, Y1
Harvey, PJ1
Li, X1
Bennett, DJ2
López-Guerrero, JJ1
Ibarra, M1
Villalobos-Molina, R1
Barthélemy, D1
Leblond, H1
Provencher, J2
Albarrán-Juárez, JA1
Lozano-Cuenca, J1
Pertz, HH1
Görnemann, T1
Nakagawa, Y3
Chin, W1
Imai, S3
Demichel, P1
Gomond, P1
Roquebert, J1
Timmermans, PB6
Thoolen, MJ6
Mathy, MJ4
Wilffert, B6
De Jonge, A6
Van Zwieten, PA8
Matthews, WD1
Demarinis, RM1
Hieble, JP1
Doods, HN1
Ishii, K1
Kato, R1
Zomlefer, MR1
Blanchette, G1
Cavero, I1
Lefevre-Borg, F1
Lhoste, F2
Sabatier, C1
Richer, C2
Giudicelli, JF1
Takeda, K1
Hashimoto, T1
Sakurai, H1
Mitomi, A1
Hamamura, M1
Kumada, M1
Medvedev, OS1
Vylegzhanin, AG1
Matsievskiĭ, DD1
Takahashi, T1
Luo, L1
Wiesenfeld-Hallin, Z4
Ono, H3
Fukushima, C1
Fukuda, H3
Gulati, A1
Rebello, S1
Vargas, HM1
Zhou, L1
Gorman, AJ1
Moorman, SJ1
Whalen, LR1
Angel, I1
Grosset, A1
Perrault, G1
Schoemaker, H1
Langer, SZ1
Nakamura, T2
Tanabe, M2
Kozuka, M1
Iwata, N2
Xu, XJ3
Wikberg, JE1
Andell, S1
Hao, JX1
Bartfai, T1
Prieto, P1
Carrón, R1
Montero, MJ1
Morán, A1
Román, LS1
Beenen, OH1
Pfaffendorf, M1
Nomura, S1
Sunagane, N1
Uruno, T1
Kubota, K1
De Serres, SJ1
Stein, RB1
Alvarez-Guerra, M1
Bertholom, N1
Garay, RP1
Szabo, B3
Bock, C1
Nordheim, U1
Niederhoffer, N1
Feng, Q1
Sun, X1
Lu, X1
Edvinsson, L1
Hedner, T1
Marcoux, J1
Rives, JE1
Bernard, DG1
Advokat, C1
Kobinger, W4
Pichler, L4
Davis, M1
Cedarbaum, JM1
Aghajanian, GK1
Gendelman, DS1
Tadepalli, AS1
Mills, E1
Miller, S1
Van Der Burg, J1
Van Der Meché, F1
Maj, J2
Palider, W1
Baran, L1
Trolin, G1
Pompeiano, O3
Ma, S1
Long, JP1
Bhatnagar, RK1
Serdiuchenko, IIa1
Koropova, GE1
Shcherbinina, MB1
Berridge, TL1
Doxey, JC1
Roach, AG1
Smith, CF1
Puke, MJC1
Tabrizchi, R2
Triggle, CR2
Pearson, KG1
Jiang, W1
Ramirez, JM1
Kaneko, T1
Tonohiro, T1
Kehne, JH1
Ketteler, HJ1
Kane, JM1
McCloskey, TC1
Senyah, Y1
Palfreyman, MG1
Gomez, RE1
Ernsberger, P1
Feinland, G1
Reis, DJ1
Rabloczky, G1
Jaszlits, L1
Horváth, E1
Dabiré, H2
Horn, E2
d'Ascanio, P2
Rawlow, A1
King, RG1
Bouhelal, R1
Loubatières-Mariani, MM1
Mir, AK1
Smyth, DD1
Blandford, DE1
Li, P1
Penner, SB1
Nakahara, H1
Chin, WP1
Jonkman, FA2
Man, PW1
Breurkes, R1
Murata, K1
Nakagawa, I1
Kumeta, Y1
Kitahata, LM1
Collins, JG1
Szemeredi, K2
Zukowska-Grojec, Z3
Bagdy, G2
Fekete, MI1
Kopin, IJ4
Galeano, C1
Corcos, J1
Carmel, M1
Jubelin, B1
Hedler, L3
Starke, K3
Skuza, G1
Sowińska, H1
Nowak, G1
Schomburg, ED1
Steffens, H1
Savola, JM1
Puurunen, J1
Ruskoaho, H1
Kärki, NT1
Joly, G1
Mouillé, P2
Schmitt, H3
van den Berg, G1
Qian, JQ1
Dausse, JP1
Fournier, B1
Cardot, A1
Meyer, P1
Skarsfeldt, T1
Hyttel, J1
Pettibone, DJ2
Clineschmidt, BV2
Lotti, VJ2
Martin, GE1
Huff, JR2
Randall, WC1
Vacca, J2
Baldwin, JJ1
Chen, DF1
Bianchetti, M1
Wiesendanger, M1
Koenig-Berard, E1
Tierney, C1
Beau, B1
Delbarre, G1
Labrid, C1
Hucker, HB1
Sweeney, BM1
Reiss, DR1
Lis, EV1
Clarke, RW1
Ford, TW1
Taylor, JS1
Ruffolo, RR1
Messick, K1
Ensinger, H1
Majewski, H1
Haass, M1
Goldstein, DS1
Sanders, KH1
Kilian, U1
Kolassa, N1
Schoetensack, W1
Tremblay, LE1
Bedard, PJ1
Rawłów, A1
Górka, Z1
Finberg, JP1
Franz, DN1
Peterson, RG1
Madsen, PW1
Sangdee, C1
Conway, BA1
Hultborn, H1
Kiehn, O1
Mintz, I1
Hill, J1
Barbeau, H1
Julien, C1
Stampacchia, G1
Zhao, ZQ1
Duggan, AW1
Matsumoto, K1
Kato, K1
Kato, F1
Miyamoto, M1
Mori, T1
Oka, J1
Gradin, K1
Dahlöf, C1
Persson, B1
Gutkind, JS1
Kazanietz, M1
Enero, MA1
Beckeringh, JJ1
Fenard, S1
Klevans, LR1
Kepner, K1
Kovacs, JL1

Reviews

1 review available for clonidine and Decerebrate Posturing

ArticleYear
Locus coeruleus and dorsal pontine reticular influences on the gain of vestibulospinal reflexes.
    Progress in brain research, 1991, Volume: 88

    Topics: Action Potentials; Animals; Carbachol; Cats; Cholinergic Fibers; Clonidine; Decerebrate State; Drug

1991

Other Studies

100 other studies available for clonidine and Decerebrate Posturing

ArticleYear
Evidence that some imidazoline derivatives inhibit peripherally the vasopressor sympathetic outflow in pithed rats.
    Autonomic neuroscience : basic & clinical, 2008, Dec-05, Volume: 143, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Agmatine; Animals; Antihypertensive Agents; Azepines; Blood Pressure; Blo

2008
Contribution of cutaneous inputs from the hindpaw to the control of locomotion. II. Spinal cats.
    Journal of neurophysiology, 2003, Volume: 90, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Biomechanical Phenomena; Cats; Clonidine; Decerebrate State; Den

2003
Spastic long-lasting reflexes of the chronic spinal rat studied in vitro.
    Journal of neurophysiology, 2004, Volume: 91, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Biogenic Monoamines; Clonidine; Decerebrate State; Dose-Response

2004
Postjunctional alpha1-adrenoceptors in the vasculature of the pithed mouse are of the alpha1A-subtype.
    Autonomic & autacoid pharmacology, 2005, Volume: 25, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Caro

2005
Nonlocomotor and locomotor hindlimb responses evoked by electrical microstimulation of the lumbar cord in spinalized cats.
    Journal of neurophysiology, 2006, Volume: 96, Issue:6

    Topics: Adrenergic alpha-Agonists; Animals; Biomechanical Phenomena; Cats; Clonidine; Decerebrate State; Ele

2006
Pharmacological profile of the clonidine-induced inhibition of vasodepressor sensory outflow in pithed rats: correlation with alpha(2A/2C)-adrenoceptors.
    British journal of pharmacology, 2008, Volume: 154, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Blood Vessels; Cal

2008
[Effects of guanfacine on pre- and postsynaptic alpha-adrenoceptors studied in comparison with those of clonidine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1982, Volume: 79, Issue:5

    Topics: Adrenalectomy; Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Clonidine; Decerebrate S

1982
alpha-Adrenoceptor blocking properties of raubasine in pithed rats.
    British journal of pharmacology, 1982, Volume: 77, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Elect

1982
Sgd 101/75 is distinguished from other selective alpha 1-adrenoceptor agonists by the inhibition of its pressor responses by calcium entry blockade and vasodilatation in pithed rats and cats.
    European journal of pharmacology, 1983, Dec-23, Volume: 96, Issue:3-4

    Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Blood Pressure; Calcium Channel Blockers; Cats; Cloni

1983
Alpha 1-adrenoceptor-mediated vasoconstriction in vivo to enantiomers of SK & F 89748-A.
    European journal of pharmacology, 1984, May-18, Volume: 101, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Cats; Clonidine; Decerebra

1984
Development of tolerance to alpha-2 adrenergic agonists in the vascular system of the rat after chronic treatment with clonidine.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Decerebrate State; Drug Tolerance; Ma

1984
Electromyographic study of lumbar back muscles during locomotion in acute high decerebrate and in low spinal cats.
    Brain research, 1984, Jan-09, Volume: 290, Issue:2

    Topics: Animals; Cats; Clonidine; Decerebrate State; Electromyography; Locomotion; Motor Activity; Muscles;

1984
Pharmacological, hemodynamic and autonomic nervous system mechanisms responsible for the blood pressure and heart rate lowering effects of pergolide in rats.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 228, Issue:3

    Topics: Adrenalectomy; Animals; Antiparkinson Agents; Autonomic Nervous System; Blood Pressure; Clonidine; D

1984
[Antihypertensive effect of guanfacine in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 77, Issue:3

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Consciousness; Decerebrate

1981
[Effect of clonidine and naloxone in somatovegetative responses in decerebrate cats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1981, Volume: 91, Issue:10

    Topics: Animals; Autonomic Nervous System; Blood Pressure; Cardiac Output; Cats; Clonidine; Decerebrate Stat

1981
[Alpha adrenergic mechanism on the reflex micturition in the male decerebrate dog].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1993, Volume: 84, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Clonidine; Decerebrate State; Dogs

1993
Low-dose intrathecal clonidine releases tachykinins in rat spinal cord.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Animals; Biphenyl Compounds; Clonidine; Decerebrate State; Hypnotics and Sedatives; Injections, Spin

1993
Effect of the centrally acting muscle relaxant tizanidine on spinal reflexes: involvement of descending noradrenergic systems.
    Japanese journal of pharmacology, 1993, Volume: 62, Issue:4

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-A

1993
Role of adrenergic mechanisms in the pressor effect of diaspirin cross-linked hemoglobin.
    The Journal of laboratory and clinical medicine, 1994, Volume: 124, Issue:1

    Topics: Adrenal Medulla; Adrenalectomy; Adrenergic beta-Antagonists; Animals; Aspirin; Blood Pressure; Cardi

1994
Role of vascular alpha-1 adrenoceptor subtypes in the pressor response to sympathetic nerve stimulation in the pithed rat.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2

    Topics: Animals; Blood Pressure; Blood Vessels; Clonidine; Decerebrate State; Dioxanes; Electric Stimulation

1994
A model system to determine the effects of specific neurotransmitters on segmental reflexes in the spinal cord of the rat.
    Journal of neuroscience methods, 1993, Volume: 46, Issue:1

    Topics: Animals; Clonidine; Decerebrate State; Dopamine; Electromyography; Electrophysiology; Female; Hindli

1993
In vivo pharmacological profile of SL 84.0418, a new selective, peripherally active alpha 2-adrenoceptor antagonist.
    European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Glucose; Blood Pressure; Bri

1993
Local cerebral glucose utilization in rats with decerebrate rigidity and effects of centrally acting muscle relaxants, diazepam and tizanidine.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:1

    Topics: Animals; Cerebellar Nuclei; Clonidine; Decerebrate State; Deoxyglucose; Diazepam; Glucose; Male; Mus

1993
The effect of intrathecal guanfacine and clonidine on the flexor reflex in rats with intact and sectioned sciatic nerves.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Analgesia; Animals; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Female; Guanfaci

1993
The effects of intrathecal galanin message-associated peptide (GMAP) on the flexor reflex in rats.
    Regulatory peptides, 1995, Jul-21, Volume: 58, Issue:1-2

    Topics: Analgesics, Opioid; Animals; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Female;

1995
MR-14134, a new benzothiazepine with central hypotensive action.
    Pharmacology, 1995, Volume: 51, Issue:2

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Antihypertensive Agents; Binding, Competitive; Bl

1995
Opposite influences of hypertension and diabetes mellitus on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed rats.
    Blood pressure, 1996, Volume: 5, Issue:1

    Topics: Adrenergic alpha-Agonists; Angiotensin II; Animals; Azepines; Blood Glucose; Blood Pressure; Brimoni

1996
Characteristics of depression by clonidine of the pressor response to alpha 1-adrenoceptor agonists in pithed rats.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 91, Issue:3

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agon

1996
Regulation of soleus muscle spindle sensitivity in decerebrate and spinal cats during postural and locomotor activities.
    The Journal of physiology, 1996, Sep-15, Volume: 495 ( Pt 3)

    Topics: Action Potentials; Afferent Pathways; Animals; Cats; Clonidine; Decerebrate State; Electrophysiology

1996
Selective blockade by nicergoline of vascular responses elicited by stimulation of alpha 1A-adrenoceptor subtype in the rat.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An

1999
Mechanism of the sympathoinhibition produced by the clonidine-like drugs rilmenidine and moxonidine.
    Annals of the New York Academy of Sciences, 1999, Jun-21, Volume: 881

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Benzazepi

1999
Decreased responsiveness of vascular postjunctional alpha1-, alpha2-adrenoceptors and neuropeptide Y1 receptors in rats with heart failure.
    Acta physiologica Scandinavica, 1999, Volume: 166, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Atrial Natriuretic Factor; Autonomic Fibers, Preganglionic; Azep

1999
Initiating or blocking locomotion in spinal cats by applying noradrenergic drugs to restricted lumbar spinal segments.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Nov-15, Volume: 20, Issue:22

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Clonidine; Decerebrate State

2000
Alpha2 adrenergic receptors and the central control of breathing in the cane toad, Bufo marinus.
    Respiration physiology, 2001, Volume: 125, Issue:3

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Bufo marinus; Clon

2001
Spinal transection increases the potency of clonidine on the tail-flick and hindlimb flexion reflexes.
    European journal of pharmacology, 2002, Feb-15, Volume: 437, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Decerebrate State; Dose-Response Relationship, Drug;

2002
Pharmacological characterization of B-HT 933 (2-amino-6-ethyl-4,5,7,8,-tetrahydro-6H-oxazolo-[5,4-d]-azepindihydrochloride) as a hypotensive agent of the "clonidine-type".
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 300, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Azepines; Cardiac Output; Cats; Central

1977
The central modulatory effect of clonidine on the cardiodepressor reflex after suppression of synthesis and storage of noradrenaline.
    European journal of pharmacology, 1975, Volume: 30, Issue:1

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Brain; Clonidine; Decerebrate

1975
Localization in the CNA of adrenoceptors which facilitate a cardioinhibitory reflex.
    Naunyn-Schmiedeberg's archives of pharmacology, 1975, Volume: 286, Issue:4

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Cerebellum; Clonidine; Decereb

1975
Effects of clonidine on habituation and sensitization of acoustic startle in normal, decerebrate and locus coeruleus lesioned rats.
    Psychopharmacology, 1977, Mar-16, Volume: 51, Issue:3

    Topics: Acoustic Stimulation; Animals; Cerebral Ventricles; Clonidine; Decerebrate State; Drug Interactions;

1977
Contribution of supracollicular structures of the brain to the central depression of cardiovascular function by clonidine.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 205, Issue:3

    Topics: Animals; Brain; Carotid Arteries; Cats; Cerebral Aqueduct; Clonidine; Decerebrate State; Depression,

1978
Locomotion in the cat: basic programmes of movement.
    Brain research, 1975, Jun-27, Volume: 91, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cats; Clonidine; Decerebrate State; Forelimb; Gait; Hindlimb; Levodopa

1975
The effects of serotonergic and antiserotonergic drugs on the flexor reflex of spinal rat: a proposed model to evaluate the action on the central serotonin receptor.
    Journal of neural transmission, 1976, Volume: 38, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anthracenes; Clonidine; Cyproheptadine; Decerebrate State

1976
Effects of pentobarbitone and decerebration on the clonidine-induced circulatory changes.
    European journal of pharmacology, 1975, Volume: 34, Issue:1

    Topics: Animals; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Drug Intera

1975
Noradrenergic and cholinergic modulations of corticocerebellar activity modify the gain of vestibulospinal reflexes.
    Annals of the New York Academy of Sciences, 1992, May-22, Volume: 656

    Topics: Animals; Cats; Cerebellum; Cerebral Cortex; Clonidine; Decerebrate State; Isoproterenol; Methoxamine

1992
Further studies on central actions of nitroglycerin and lack of evidence for nitroglycerin interacting on [3H]clonidine binding sites in cortex membranes.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Animals; Binding Sites; Blood Pressure; Brain; Clonidine; Decerebrate State; Heart Rate; Injections,

1992
[Segmental reflexes after sciatic nerve damage in rats given thyroxine].
    Neirofiziologiia = Neurophysiology, 1992, Volume: 24, Issue:6

    Topics: Animals; Clonidine; Decerebrate State; Female; Injections, Intraperitoneal; Propranolol; Rats; Refle

1992
Selectivity profile of the alpha 2-adrenoceptor antagonist efaroxan in relation to plasma glucose and insulin levels in the rat.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Benzofurans; Blood Glucose; Brimonidine Tartrate; Clonidine;

1992
The depressive effect of intrathecal clonidine on the spinal flexor reflex is enhanced after sciatic nerve section in rats.
    Pain, 1992, Volume: 51, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Axons; Blood Pressure; Clonidine; Decerebrate State; Female;

1992
The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Captopril; Clonidine; Decerebrate Stat

1992
The use of naloxone to facilitate the generation of the locomotor rhythm in spinal cats.
    Journal of neuroscience methods, 1992, Volume: 42, Issue:1-2

    Topics: Animals; Cats; Clonidine; Decerebrate State; Electromyography; Motor Activity; Naloxone; Physical St

1992
The pharmacological properties of CS-722, a newly synthesized centrally acting muscle relaxant.
    Neuropharmacology, 1992, Volume: 31, Issue:10

    Topics: Animals; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Electroencephalography; Evo

1992
MDL 27,531 reduces spontaneous hindlimb contractions in rats with chronic transections of the spinal cord.
    Neuroscience letters, 1992, Nov-23, Volume: 147, Issue:1

    Topics: Animals; Anticonvulsants; Clonidine; Decerebrate State; Hindlimb; Male; Muscle Contraction; Muscle T

1992
Rilmenidine lowers arterial pressure via imidazole receptors in brainstem C1 area.
    European journal of pharmacology, 1991, Mar-26, Volume: 195, Issue:2

    Topics: Animals; Antihypertensive Agents; Benzazepines; Binding, Competitive; Blood Pressure; Brain Stem; Cl

1991
GYKI-12743 a new postsynaptic vascular alpha-adrenoceptor antagonist.
    Acta physiologica Hungarica, 1991, Volume: 77, Issue:3-4

    Topics: Adrenergic alpha-Antagonists; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Dioxa

1991
Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine.
    Pharmacology, 1991, Volume: 43, Issue:3

    Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate Stat

1991
Implication of the central nervous system in the systemic and regional hemodynamics of two centrally acting hypotensive drugs, flesinoxan and clonidine, in the rat.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:4

    Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Central Nervous System

1991
A novel in vivo test for drugs affecting central serotonergic and adrenergic systems.
    European journal of pharmacology, 1990, Dec-04, Volume: 191, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Albuterol; Animals; Cl

1990
Investigation of the mechanism(s) of 8-OH-DPAT-mediated inhibition of plasma insulin in spontaneously hypertensive rats.
    British journal of pharmacology, 1990, Volume: 100, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Blood Glucose; Blood Pressure; Clonidin

1990
Comparison of renal and vascular alpha 2-adrenoceptor sensitivity to clonidine in the rat.
    Proceedings of the Western Pharmacology Society, 1990, Volume: 33

    Topics: Anesthesia; Animals; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relationship, Drug;

1990
Alpha-blockade and vasodilatation induced by nipradilol, arotinolol and labetalol in pithed rats.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Decer

1985
Beta 2-adrenoceptor antagonists intensify clonidine withdrawal syndrome in conscious rats.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Re

1989
Intrathecal clonidine suppresses noxiously evoked activity of spinal wide dynamic range neurons in cats.
    Anesthesia and analgesia, 1989, Volume: 69, Issue:2

    Topics: Analgesics; Animals; Blood Pressure; Cats; Clonidine; Decerebrate State; Drug Combinations; Female;

1989
Opposite effects of chronic cortisol treatment on pre- and postsynaptic actions of clonidine in pithed rats.
    Journal of autonomic pharmacology, 1989, Volume: 9, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Body Weight; Clonidine; Decerebrate St

1989
Action of clonidine on micturitional reflexes in decerebrate cats.
    Brain research, 1989, Jul-03, Volume: 491, Issue:1

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Cats; Central Nervous System; Clon

1989
Peripheral presynaptic and central effects of clonidine, yohimbine and rauwolscine on the sympathetic nervous system in rabbits.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 340, Issue:6

    Topics: Animals; Blood Pressure; Brain; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Fema

1989
Pharmacological properties of EXP 561, a potential antidepressant drug.
    Journal of neural transmission, 1987, Volume: 70, Issue:1-2

    Topics: Aggression; Amphetamine; Animals; Antidepressive Agents; Apomorphine; Behavior, Animal; Blood Pressu

1987
The effect of DOPA and clonidine on reflex pathways from group II muscle afferents to alpha-motoneurones in the cat.
    Experimental brain research, 1988, Volume: 71, Issue:2

    Topics: Action Potentials; Animals; Cats; Clonidine; Decerebrate State; Dihydroxyphenylalanine; Electric Sti

1988
Peripheral cardiovascular alpha- and beta-adrenergic effects of some hypotensive and bradycardic arylalkyl imidazole derivatives in the rat.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Clonidi

1985
Antagonistic effects of S9871 or (imidazolinyl-2)-2-dihydro 2,3 benzofurane and its stereoisomers on some central and peripheral actions of alpha 2-agonists.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 277, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Azepines; Benzofurans; Blood Press

1985
Inhibitory effect of alpha-1 adrenoceptor stimulation on cardiac sympathetic neurotransmission in pithed normotensive rats.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Decerebrate State; Ethanolamines; Heart; Heart Rate;

1986
Central and peripheral effects of S 3341 [(N-dicyclopropylmethyl)-amino-2-oxazoline] in animal models.
    Archives internationales de pharmacodynamie et de therapie, 1986, Volume: 279, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Binding, Competitive; Blood Pressure; Brain; Cats; Clonidine; De

1986
Pharmacological properties of the enantiomers of idazoxan: possible separation between their alpha-adrenoceptor blocking effects.
    Clinical and experimental hypertension. Part A, Theory and practice, 1986, Volume: 8, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Pressure; Cerebral Cortex; Chicke

1986
The St 587-induced flexor reflex in pithed rats: a model to evaluate central alpha 1-receptor blocking properties.
    European journal of pharmacology, 1986, Jun-24, Volume: 125, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Antipsychotic Agents; Binding, Competitive; Clonidine; Decere

1986
L-654,284 a new potent and selective alpha 2-adrenoceptor antagonist.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 333, Issue:2

    Topics: Adrenergic alpha-Antagonists; Animals; Cattle; Cerebral Cortex; Clonidine; Decerebrate State; Dihydr

1986
Dopamine1 receptor agonist and alpha-2 adrenoceptor antagonist effects of fenoldopam in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Clonidine; Decerebrate State; Desipramine; Domp

1986
The adrenergic agonist tizanidine has differential effects on flexor reflexes of intact and spinalized rat.
    Neuroscience, 1987, Volume: 23, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Clonidine; Decerebrate State; Dose-Response

1987
Cardiovascular and central nervous system effects of rilmenidine (S 3341) in rats.
    The American journal of cardiology, 1988, Feb-24, Volume: 61, Issue:7

    Topics: Adrenalectomy; Adrenergic alpha-Agonists; Anesthesia; Animals; Blood Pressure; Catecholamines; Centr

1988
A peripherally acting alpha-2 adrenoceptor antagonist: L-659,066.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 245, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood-Brain Barrier; Callitrichinae; Cl

1988
Adrenergic and opioidergic modulation of a spinal reflex in the decerebrated rabbit.
    The Journal of physiology, 1988, Volume: 404

    Topics: Adrenergic alpha-Antagonists; Animals; Clonidine; Decerebrate State; Dioxanes; Dioxins; Dose-Respons

1988
Evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Animals; Blood Pressure; Brimonidine Tartrate; Clonidine; Decerebrate State; Dose-Response Relations

1985
Neuronal and postjunctional components in the blood pressure effects of dopamine and bromocriptine in rabbits.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Bromocriptine; Clonidine; Decerebrate State; Desi

1985
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4

    Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Dr

1985
Differential inhibition of alpha adrenoceptor-mediated pressor responses by rat atrial natriuretic peptide in the pithed rat.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Atrial Natriuretic Factor; Blood Pressure; Clonidine; Decereb

1985
Influence of urapidil on alpha- and beta-adrenoreceptors in pithed rats.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:4

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Decerebrate State; Dose-Response Relati

1985
Effect of clonidine on motoneuron excitability in spinalized rats.
    Neuropharmacology, 1986, Volume: 25, Issue:1

    Topics: Animals; Anterior Horn Cells; Clonidine; Decerebrate State; Depression, Chemical; Efferent Pathways;

1986
Involvement of postsynaptic alpha 1- and alpha 2-adrenoceptors in the flexor reflex activity in the spinal rats.
    Journal of neural transmission, 1986, Volume: 66, Issue:2

    Topics: Animals; Clonidine; Clozapine; Decerebrate State; Male; Norepinephrine; Prazosin; Rats; Rats, Inbred

1986
Chronic clonidine treatment produces desensitisation of post- but not presynaptic alpha 2-adrenoceptors.
    European journal of pharmacology, 1987, Jun-12, Volume: 138, Issue:1

    Topics: Animals; Blood Pressure; Body Weight; Catecholamines; Clonidine; Decerebrate State; Dose-Response Re

1987
Enhancement of central transmission to sympathetic preganglionic neurons by phosphodiesterase inhibitors and its prevention by clonidine.
    Journal of the autonomic nervous system, 1987, Volume: 19, Issue:3

    Topics: Animals; Catecholamines; Cats; Clonidine; Decerebrate State; Female; Ganglia; Male; Neurons; Phospho

1987
Plateau potentials in alpha-motoneurones induced by intravenous injection of L-dopa and clonidine in the spinal cat.
    The Journal of physiology, 1988, Volume: 405

    Topics: Action Potentials; Animals; Cats; Clonidine; Decerebrate State; Levodopa; Membrane Potentials; Motor

1988
Evidence for a direct peripheral effect of clonidine on the norepinephrine release in vivo in pithed rats.
    European journal of pharmacology, 1988, Jan-19, Volume: 145, Issue:3

    Topics: Animals; Blood Pressure; Clonidine; Decerebrate State; Male; Norepinephrine; Peripheral Nerves; Rats

1988
The effects of clonidine and yohimbine on locomotion and cutaneous reflexes in the adult chronic spinal cat.
    Brain research, 1987, Dec-22, Volume: 437, Issue:1

    Topics: Animals; Cats; Clonidine; Decerebrate State; Electromyography; Gait; Locomotion; Reflex; Skin; Skin

1987
Effects of local injection of the alpha 2-adrenergic agonist clonidine into the locus coeruleus complex on the gain of vestibulospinal and cervicospinal reflexes in decerebrate cats.
    Archives italiennes de biologie, 1987, Volume: 125, Issue:3

    Topics: Animals; Cats; Clonidine; Decerebrate State; Electromyography; Functional Laterality; Locus Coeruleu

1987
Clonidine and the hyper-responsiveness of dorsal horn neurones following morphine withdrawal in the spinal cat.
    Neuropharmacology, 1987, Volume: 26, Issue:10

    Topics: Animals; Cats; Clonidine; Decerebrate State; Ganglia, Spinal; Injections; Injections, Intravenous; M

1987
Effects of tizanidine, a centrally acting muscle relaxant, on motor systems.
    General pharmacology, 1986, Volume: 17, Issue:2

    Topics: Animals; Cerebral Cortex; Chlorpromazine; Clonidine; Decerebrate State; Diazepam; Male; Membranes; M

1986
A low dietary sodium intake reduces neuronal noradrenaline release and the blood pressure in spontaneously hypertensive rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:4

    Topics: Animals; Catecholamines; Clonidine; Decerebrate State; Diet, Sodium-Restricted; Electric Stimulation

1986
Cardiovascular effects of alpha-adrenergic drugs: differences between clonidine and guanabenz.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:4

    Topics: Animals; Blood Pressure; Brain; Clonidine; Decerebrate State; Dopamine; Female; Guanabenz; Guanidine

1986
Cardiovascular effects and interaction with adrenoceptors of urapidil.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 276, Issue:2

    Topics: Animals; Antihypertensive Agents; Binding, Competitive; Cats; Clonidine; Decerebrate State; Female;

1985
Evidence for direct alpha-adrenoceptor stimulation of effector neurons in cardiovascular centers by clonidine.
    European journal of pharmacology, 1974, Volume: 27, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II; Animals; Blood Pressure; Card

1974
Localization of the site of the central sympatho-inhibitory action of 1-Dopa in dogs and cats.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Stem; Carbidopa; Cats;

1973
Role of forebrain in clonidine-induced suppression of cardiovascular responses.
    European journal of pharmacology, 1973, Volume: 24, Issue:2

    Topics: Animals; Blood Pressure; Brain; Cats; Clonidine; Decamethonium Compounds; Decerebrate State; Electri

1973
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