Page last updated: 2024-10-25

clonidine and Complications, Pregnancy

clonidine has been researched along with Complications, Pregnancy in 11 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"In order to prevent symptoms of drug withdrawal during pregnancy, we treated a woman with clonidine, an alpha-2 adrenergic agonist with central and peripheral actions."7.67[Treatment of withdrawal symptoms using clonidine during pregnancy]. ( Heidenreich, W; Knitsch, W; Plein, S; Pohl, S, 1989)
" With the exception of one subject, all pre-eclamptics were taking clonidine (a known suppressant of rapid eye movement-REM-sleep) for control of their hypertension."3.70Pre-eclampsia is associated with marked alterations in sleep architecture. ( Blyton, CM; Edwards, N; Kesby, GJ; Sullivan, CE; Wilcox, I, 2000)
" The amniotic fluid norepinephrine concentration (mean +/- SD) in cases of hypertension treated with clonidine (0."3.67Amniotic fluid norepinephrine concentration as an indicator of fetal sympathetic nervous activity. Effect of pregnancy complications. ( Kauppila, A; Puolakka, J; Vuori, J, 1984)
"In order to prevent symptoms of drug withdrawal during pregnancy, we treated a woman with clonidine, an alpha-2 adrenergic agonist with central and peripheral actions."3.67[Treatment of withdrawal symptoms using clonidine during pregnancy]. ( Heidenreich, W; Knitsch, W; Plein, S; Pohl, S, 1989)
"When opioid misuse rises in the United States, pregnant women and their neonates are affected."2.61Analgesia, Opioids, and Other Drug Use During Pregnancy and Neonatal Abstinence Syndrome. ( Jones, HE; Kraft, WK, 2019)
" Chronic administration of drugs acting on monoamines (such as clonidine, imipramine, alpha-methyl-Dopa, reserpine, monoamine oxidase inhibitors, diazepam) disturb the spontaneous activity and behavioral state dependency of the monoaminergic cells, influences neurotransmitter turnover and change the sensitivity of both pre- and post-synaptic receptors."2.37Central neurotransmitter disturbances underlying developmental neurotoxicological effects. ( Mirmiran, M; Swaab, DF, 1986)
"Clonidine use was assessed in 90 treatment-seeking, pregnant, opiate-abusing women using both self-report and urinalysis toxicology."1.30Illicit use of clonidine in opiate-abusing pregnant women. ( Anderson, F; Huggins, G; Lee, J; Paluzzi, P; Svikis, D, 1997)
"Women with mild withdrawal symptoms were given clonidine initially, and methadone was substituted if symptoms persisted."1.30Opioid detoxification in pregnancy. ( Dashe, JS; Jackson, GL; Olscher, DA; Wendel, GD; Zane, EH, 1998)
"Female rats were subjected to stress treatments during pregnancy and the offspring were studied at several different ages."1.27Prenatal stress: effect on development of rat brain adrenergic receptors. ( Peters, DA, 1984)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's2 (18.18)18.2507
2000's1 (9.09)29.6817
2010's3 (27.27)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Elkoundi, A1
Mounir, K1
Atmani, W1
Balkhi, H1
Leavitt, K1
Običan, S1
Yankowitz, J1
Jones, HE1
Kraft, WK1
Bagley, SM1
Wachman, EM1
Holland, E1
Brogly, SB1
Peters, DA1
Puolakka, J1
Kauppila, A1
Vuori, J1
Anderson, F1
Paluzzi, P1
Lee, J1
Huggins, G1
Svikis, D1
Dashe, JS1
Jackson, GL1
Olscher, DA1
Zane, EH1
Wendel, GD1
Edwards, N1
Blyton, CM1
Kesby, GJ1
Wilcox, I1
Sullivan, CE1
Pohl, S1
Heidenreich, W1
Plein, S1
Knitsch, W1
Mirmiran, M1
Swaab, DF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Randomized Comparative Effectiveness Clinical Trial of Buprenorphine vs. Methadone for the Treatment of Opioid Dependence in Pregnancy.[NCT03098407]55 participants (Actual)Interventional2017-04-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for clonidine and Complications, Pregnancy

ArticleYear
Treatment and Prevention of Hypertensive Disorders During Pregnancy.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aspirin; Calcium Channel Blockers; Chronic Dis

2019
Analgesia, Opioids, and Other Drug Use During Pregnancy and Neonatal Abstinence Syndrome.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Breast Feeding; Buprenorphine; Buprenorphine

2019
Review of the assessment and management of neonatal abstinence syndrome.
    Addiction science & clinical practice, 2014, Sep-09, Volume: 9, Issue:1

    Topics: Breast Feeding; Buprenorphine; Clonidine; Female; Humans; Infant, Newborn; Methadone; Narcotics; Neo

2014
Central neurotransmitter disturbances underlying developmental neurotoxicological effects.
    Neurotoxicology, 1986,Summer, Volume: 7, Issue:2

    Topics: Animals; Brain; Clonidine; Drug Interactions; Female; Growth; Humans; Neurotoxins; Neurotransmitter

1986

Other Studies

7 other studies available for clonidine and Complications, Pregnancy

ArticleYear
Management of a patient with Shapiro syndrome variant during pregnancy.
    International journal of obstetric anesthesia, 2020, Volume: 43

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Agenesis of Corpus Callosum; Clonidine; Diagnosis, Diff

2020
Prenatal stress: effect on development of rat brain adrenergic receptors.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 21, Issue:3

    Topics: Age Factors; Analysis of Variance; Animals; Brain; Clonidine; Dihydroalprenolol; Dioxanes; Female; P

1984
Amniotic fluid norepinephrine concentration as an indicator of fetal sympathetic nervous activity. Effect of pregnancy complications.
    Gynecologic and obstetric investigation, 1984, Volume: 17, Issue:5

    Topics: Amniotic Fluid; Clonidine; Female; Humans; Hypertension; Kidney Diseases; Norepinephrine; Pregnancy;

1984
Illicit use of clonidine in opiate-abusing pregnant women.
    Obstetrics and gynecology, 1997, Volume: 90, Issue:5

    Topics: Adult; Antihypertensive Agents; Case-Control Studies; Clonidine; Female; Humans; Opioid-Related Diso

1997
Opioid detoxification in pregnancy.
    Obstetrics and gynecology, 1998, Volume: 92, Issue:5

    Topics: Adult; Analgesics; Analgesics, Opioid; Chi-Square Distribution; Clonidine; Drug Therapy, Combination

1998
Pre-eclampsia is associated with marked alterations in sleep architecture.
    Sleep, 2000, Aug-01, Volume: 23, Issue:5

    Topics: Adult; Antihypertensive Agents; Clonidine; Electroencephalography; Electrooculography; Female; Human

2000
[Treatment of withdrawal symptoms using clonidine during pregnancy].
    Der Anaesthesist, 1989, Volume: 38, Issue:9

    Topics: Adult; Clonidine; Female; Humans; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome

1989