clonidine has been researched along with Complex Regional Pain Syndromes in 10 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Complex Regional Pain Syndromes: Conditions characterized by pain involving an extremity or other body region, HYPERESTHESIA, and localized autonomic dysfunction following injury to soft tissue or nerve. The pain is usually associated with ERYTHEMA; SKIN TEMPERATURE changes, abnormal sudomotor activity (i.e., changes in sweating due to altered sympathetic innervation) or edema. The degree of pain and other manifestations is out of proportion to that expected from the inciting event. Two subtypes of this condition have been described: type I; (REFLEX SYMPATHETIC DYSTROPHY) and type II; (CAUSALGIA). (From Pain 1995 Oct;63(1):127-33)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy of intravenous regional anesthesia (IVRA) with clonidine in patients with a previous history of complex regional pain syndrome (CRPS) who are undergoing upper extremity hand surgery." | 9.11 | Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine. ( Faruqi, S; Kilaru, PA; Reuben, SS; Rosenthal, EA; Steinberg, RB, 2004) |
| "Evidence suggests that complex regional pain syndrome (CRPS) is a manifestation of microvascular dysfunction." | 5.43 | A Novel Compound Analgesic Cream (Ketamine, Pentoxifylline, Clonidine, DMSO) for Complex Regional Pain Syndrome Patients. ( Russo, MA; Santarelli, DM, 2016) |
| "To evaluate the efficacy of intravenous regional anesthesia (IVRA) with clonidine in patients with a previous history of complex regional pain syndrome (CRPS) who are undergoing upper extremity hand surgery." | 5.11 | Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine. ( Faruqi, S; Kilaru, PA; Reuben, SS; Rosenthal, EA; Steinberg, RB, 2004) |
| " We prospectively evaluated the use of four anesthetic techniques (general anesthesia, axillary block, and IV regional anesthesia [IVRA] with lidocaine with or without clonidine) for patients undergoing fasciectomy for Dupuytren's contracture." | 3.73 | The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques. ( Dixon, D; Faruqi, S; Madabhushi, L; Pristas, R; Reuben, SS; Wenner, S, 2006) |
| "Chronic pain may be accompanied by hyperalgesia and allodynia, and analgesic interventions may reduce these hypersensitivity phenomena." | 2.80 | Intrathecal clonidine and adenosine: effects on pain and sensory processing in patients with chronic regional pain syndrome. ( Eisenach, JC; North, J; Rauck, RL, 2015) |
| "The prevalences of complex regional pain syndrome, phantom limb pain, chronic donor-site pain, and persistent pain following total joint arthroplasty are alarmingly high." | 2.44 | Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques. ( Buvanendran, A; Reuben, SS, 2007) |
| "Evidence suggests that complex regional pain syndrome (CRPS) is a manifestation of microvascular dysfunction." | 1.43 | A Novel Compound Analgesic Cream (Ketamine, Pentoxifylline, Clonidine, DMSO) for Complex Regional Pain Syndrome Patients. ( Russo, MA; Santarelli, DM, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (50.00) | 29.6817 |
| 2010's | 5 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Herring, EZ | 1 |
| Frizon, LA | 1 |
| Hogue, O | 1 |
| Mejia, JU | 1 |
| Rosenquist, R | 1 |
| Bolash, RB | 1 |
| Machado, AG | 1 |
| Nagel, SJ | 1 |
| Drummond, PD | 1 |
| Morellini, N | 1 |
| Finch, PM | 1 |
| Birklein, F | 1 |
| Knudsen, LF | 1 |
| Rauck, RL | 1 |
| North, J | 1 |
| Eisenach, JC | 1 |
| Russo, MA | 1 |
| Santarelli, DM | 1 |
| Dizdarevic, A | 1 |
| Bremer, N | 1 |
| Reuben, SS | 3 |
| Rosenthal, EA | 1 |
| Steinberg, RB | 1 |
| Faruqi, S | 2 |
| Kilaru, PA | 1 |
| Pristas, R | 1 |
| Dixon, D | 1 |
| Madabhushi, L | 1 |
| Wenner, S | 1 |
| Chen, LC | 1 |
| Wong, CS | 1 |
| Huh, BK | 1 |
| Huang, YS | 1 |
| Yang, CP | 1 |
| Yeh, CC | 1 |
| Wu, CT | 1 |
| Giri, S | 1 |
| Nixdorf, D | 1 |
| Buvanendran, A | 1 |
1 review available for clonidine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics; Anesthetics, Local; Anima | 2007 |
2 trials available for clonidine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Intrathecal clonidine and adenosine: effects on pain and sensory processing in patients with chronic regional pain syndrome.
Topics: Adenosine; Adult; Analgesics; Chronic Pain; Clonidine; Complex Regional Pain Syndromes; Cross-Over S | 2015 |
Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine.
Topics: Anesthesia, Conduction; Anesthetics, Combined; Anesthetics, Intravenous; Clonidine; Complex Regional | 2004 |
7 other studies available for clonidine and Complex Regional Pain Syndromes
| Article | Year |
|---|---|
Long-term Outcomes Using Intrathecal Drug Delivery Systems in Complex Regional Pain Syndrome.
Topics: Administration, Oral; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; A | 2019 |
Complex regional pain syndrome: intradermal injection of phenylephrine evokes pain and hyperalgesia in a subgroup of patients with upregulated α1-adrenoceptors on dermal nerves.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Clonidine; | 2018 |
A Novel Compound Analgesic Cream (Ketamine, Pentoxifylline, Clonidine, DMSO) for Complex Regional Pain Syndrome Patients.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics; Anesthetics, Dissociative; Anti-Infective Agents, Loca | 2016 |
Cervical Spinal Cord Stimulation with Concomitant Serotonin Norepinephrine Reuptake Inhibitor Therapy Leading to the Serotonin Syndrome.
Topics: Adult; Analgesics; Cervical Vertebrae; Clonidine; Complex Regional Pain Syndromes; Diclofenac; Drug | 2017 |
The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques.
Topics: Aged; Anesthesia; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Intravenous; Arm; Axilla; | 2006 |
Repeated lumbar sympathetic blockade with lidocaine and clonidine attenuates pain in complex regional pain syndrome type 1 patients--a report of two cases.
Topics: Adult; Autonomic Nerve Block; Clonidine; Complex Regional Pain Syndromes; Humans; Lidocaine; Lumbosa | 2006 |
Sympathetically maintained pain presenting first as temporomandibular disorder, then as parotid dysfunction.
Topics: Adrenergic alpha-Agonists; Adult; Anesthetics, Local; Autonomic Nervous System Diseases; Bupivacaine | 2007 |