Page last updated: 2024-10-25

clonidine and Colonic Neoplasms

clonidine has been researched along with Colonic Neoplasms in 13 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Colonic Neoplasms: Tumors or cancer of the COLON.

Research Excerpts

ExcerptRelevanceReference
"In the present work, [3H]clonidine was used to characterize alpha 2-adrenoceptors on the human adenocarcinoma cell line HT 29."7.67alpha 2-Adrenoceptors in the HT 29 human colon adenocarcinoma cell line: characterization with [3H]clonidine; effects on cyclic AMP accumulation. ( Bouscarel, B; Carpene, C; Cortinovis, C; Murat, JC; Paris, H, 1985)
" Despite leptomeningeal infection during prolonged treatment, epidural analgesia at the lumbar level provided analgesia using very large doses of local anesthetics combined with clonidine and morphine."3.72Epidural analgesia at end of life: facing empirical contraindications. ( Eikermann, M; Exner, HJ; Peters, J, 2003)
"In the present work, [3H]clonidine was used to characterize alpha 2-adrenoceptors on the human adenocarcinoma cell line HT 29."3.67alpha 2-Adrenoceptors in the HT 29 human colon adenocarcinoma cell line: characterization with [3H]clonidine; effects on cyclic AMP accumulation. ( Bouscarel, B; Carpene, C; Cortinovis, C; Murat, JC; Paris, H, 1985)
"Mechanical hyperalgesia was measured by von Frey filaments."2.71The short-lasting analgesia and long-term antihyperalgesic effect of intrathecal clonidine in patients undergoing colonic surgery. ( De Kock, M; Lavand'homme, P; Waterloos, H, 2005)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Forget, P1
Berlière, M1
Poncelet, A1
De Kock, M2
Pirbudak, L1
Sevinç, A1
Maralcan, G1
Kılıç, E1
Friedman, GD1
Udaltsova, N1
Habel, LA1
Exner, HJ1
Peters, J1
Eikermann, M1
Lavand'homme, P1
Waterloos, H1
Warhurst, G1
Turnberg, LA1
Higgs, NB1
Tonge, A1
Grundy, J1
Fogg, KE1
Holliday, ND1
Tough, IR1
Cox, HM1
Sénard, JM1
Mauriège, P1
Daviaud, D1
Paris, H5
Turner, JT1
Ray-Prenger, C1
Bylund, DB1
Bouscarel, B3
Cortinovis, C2
Carpene, C1
Murat, JC4
Denis, C1

Trials

1 trial available for clonidine and Colonic Neoplasms

ArticleYear
The short-lasting analgesia and long-term antihyperalgesic effect of intrathecal clonidine in patients undergoing colonic surgery.
    Anesthesia and analgesia, 2005, Volume: 101, Issue:2

    Topics: Adrenergic alpha-Agonists; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Anest

2005

Other Studies

12 other studies available for clonidine and Colonic Neoplasms

ArticleYear
Effect of clonidine on oncological outcomes after breast and lung cancer surgery.
    British journal of anaesthesia, 2018, Volume: 121, Issue:1

    Topics: Animals; Breast Neoplasms; Clonidine; Colonic Neoplasms; Dexmedetomidine; Humans; Lung Neoplasms; Ro

2018
Pain management with intrathecal clonidine in a colon cancer patient with opioid hyperalgesia: case presentation.
    Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 2014, Volume: 26, Issue:2

    Topics: Adult; Analgesics; Clonidine; Colonic Neoplasms; Diagnosis, Differential; Humans; Injections, Spinal

2014
Norepinephrine antagonists and cancer risk.
    International journal of cancer, 2011, Feb-01, Volume: 128, Issue:3

    Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Meto

2011
Epidural analgesia at end of life: facing empirical contraindications.
    Anesthesia and analgesia, 2003, Volume: 97, Issue:6

    Topics: Abdominal Pain; Adrenergic alpha-Agonists; Adult; Analgesia, Epidural; Analgesics, Opioid; Anestheti

2003
Multiple G-protein-dependent pathways mediate the antisecretory effects of somatostatin and clonidine in the HT29-19A colonic cell line.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:2

    Topics: Adenocarcinoma; Bucladesine; Calcium; Cell Differentiation; Chlorides; Cholera Toxin; Clonidine; Col

1993
Inhibition of cyclic AMP-dependent chloride secretion by PP receptors and alpha 2-adrenoceptors in a human colonic epithelial cell line.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:2

    Topics: Adenocarcinoma; Adrenergic alpha-Agonists; Chlorides; Clonidine; Colonic Neoplasms; Cyclic AMP; Depr

1997
Alpha 2-adrenoceptor in HT29 human colon adenocarcinoma cell-line: study of [3H](-)-adrenaline binding.
    European journal of pharmacology, 1989, Mar-21, Volume: 162, Issue:2

    Topics: Adenocarcinoma; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Cell Line; Cell Membrane; C

1989
Alpha 2-adrenergic receptors in the human cell line, HT29. Characterization with the full agonist radioligand [3H]UK-14,304 and inhibition of adenylate cyclase.
    Molecular pharmacology, 1985, Volume: 28, Issue:5

    Topics: Adenocarcinoma; Adenylyl Cyclase Inhibitors; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell L

1985
alpha 2-Adrenoceptors in the HT 29 human colon adenocarcinoma cell line: characterization with [3H]clonidine; effects on cyclic AMP accumulation.
    European journal of pharmacology, 1985, Jan-02, Volume: 107, Issue:2

    Topics: Adenocarcinoma; Cell Line; Clonidine; Colonic Neoplasms; Cyclic AMP; Humans; Kinetics; Receptors, Ad

1985
Growth-related variation of alpha 2-adrenergic receptivity in the HT 29 adenocarcinoma cell-line from human colon.
    FEBS letters, 1985, May-06, Volume: 184, Issue:1

    Topics: Adenocarcinoma; Cell Line; Cell Membrane; Clonidine; Colonic Neoplasms; Cyclic AMP; Humans; Receptor

1985
Involvement of guanine nucleotide and sodium in regulation of yohimbine and clonidine binding sites in the HT29 human colon adenocarcinoma cell-line.
    General pharmacology, 1985, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Binding, Competitive; Cell Line; Clonidine; Colonic Neoplasms; Epinephrine; Guanosin

1985
Hormonal control of fructose 2,6-bisphosphate concentration in the HT29 human colon adenocarcinoma cell line. Alpha 2-adrenergic agonists counteract effect of vasoactive intestinal peptide.
    The Biochemical journal, 1986, Nov-01, Volume: 239, Issue:3

    Topics: Adenocarcinoma; Brimonidine Tartrate; Cell Line; Clonidine; Colonic Neoplasms; Cyclic AMP; Epinephri

1986