Page last updated: 2024-10-25

clonidine and Colitis

clonidine has been researched along with Colitis in 5 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"As the use of the 5-HT(3) receptor antagonist alosetron (GlaxoSmithKline) and the 5-HT(4) receptor agonist tegaserod (Novartis) in patients with irritable bowel syndrome has been associated with cases of ischaemic colitis, the effects of alosetron, cilansetron (Solvay) and tegaserod on the rat splanchnic circulation were evaluated."3.75Alosetron, cilansetron and tegaserod modify mesenteric but not colonic blood flow in rats. ( Holzer, P; Painsipp, E; Shahbazian, A, 2009)
"Colitis was induced by dextran sulfate sodium (DSS, 2%); alpha2-AR ligands were injected i."1.43Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium-Induced Acute Intestinal Inflammation in Mice. ( Al-Khrasani, M; Fehér, Á; Gyires, K; Hein, L; Helyes, Z; Holzer, P; Kozsurek, M; Puskár, Z; Tábi, T; Timár, J; Tóth, VE; Zádori, ZS, 2016)
"Clonidine was used as a reference alpha 2 -adrenoceptor agonist."1.32Comparison of the visceral antinociceptive effects of spinally administered MPV-2426 (fadolmidine) and clonidine in the rat. ( Kalmari, J; Pertovaara, A, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zádori, ZS1
Tóth, VE1
Fehér, Á1
Al-Khrasani, M1
Puskár, Z1
Kozsurek, M1
Timár, J1
Tábi, T1
Helyes, Z1
Hein, L1
Holzer, P2
Gyires, K1
Gould, M1
Sellin, JH1
Painsipp, E1
Shahbazian, A1
Pertovaara, A1
Kalmari, J1
Miampamba, M1
Chéry-Croze, S1
Détolle-Sarbach, S1
Guez, D1
Chayvialle, JA1

Other Studies

5 other studies available for clonidine and Colitis

ArticleYear
Inhibition of α2A-Adrenoceptors Ameliorates Dextran Sulfate Sodium-Induced Acute Intestinal Inflammation in Mice.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 358, Issue:3

    Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Clonidine; Colitis; Dextran Sulfate; Drinking; Fem

2016
Diabetic diarrhea.
    Current gastroenterology reports, 2009, Volume: 11, Issue:5

    Topics: Algorithms; Antidiarrheals; Celiac Disease; Clonidine; Colitis; Diabetes Complications; Diabetes Mel

2009
Alosetron, cilansetron and tegaserod modify mesenteric but not colonic blood flow in rats.
    British journal of pharmacology, 2009, Volume: 158, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Carbazoles; Carbolines; Clonidine; Colitis; Colo

2009
Comparison of the visceral antinociceptive effects of spinally administered MPV-2426 (fadolmidine) and clonidine in the rat.
    Anesthesiology, 2003, Volume: 98, Issue:1

    Topics: Adrenergic alpha-Agonists; Analgesics; Anesthesia; Animals; Clonidine; Colitis; Colon; Dose-Response

2003
Antinociceptive effects of oral clonidine and S12813-4 in acute colon inflammation in rats.
    European journal of pharmacology, 1996, Jul-25, Volume: 308, Issue:3

    Topics: Acute Disease; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonidine; Colitis; Fem

1996