clonidine has been researched along with Chronic Motor and Vocal Tic Disorder in 112 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the therapeutic effectiveness and safety of clonidine adhesive patch in treating Tourette syndrome (TS)." | 9.22 | Clinical observation on treatment of Tourette syndrome in Chinese children by clonidine adhesive patch. ( Jiao, F; Wang, J; Zhang, X, 2016) |
| "We compared the efficacy of clonidine and levetiracetam for treating tics in Tourette syndrome." | 9.14 | Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome. ( Hedderick, EF; Morris, CM; Singer, HS, 2009) |
| "Levetiracetam, an anti-epileptic agent that enhances GABAergic neurotransmission, is one of the newest alternative treatments of Tourette syndrome (TS)." | 7.74 | Levetiracetam in the treatment of antipsychotics-resistant Tourette syndrome. ( Karakatsanis, NA; Karapoulios, E; Kouzoupis, AV; Masdrakis, VG; Oulis, P; Papadimitriou, GN; Papageorgiou, C; Soldatos, CR, 2008) |
| "Atomoxetine and OROS methylphenidate were successfully used concomitantly in a 10-year-old boy suffering from attention-deficit/hyperactivity disorder (ADHD) with comorbid bipolar disorder and Tourette syndrome (TS)." | 7.73 | Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome. ( Benarroch, F; Gross-Tsur, V; Jaworowski, S, 2006) |
| "Clonidine usually serves as a tic-suppressing agent in patients with Tourette syndrome." | 7.71 | Clonidine treatment increases tics in patients with Tourette syndrome: case report. ( Kessler, AR, 2001) |
| "Clonidine is an alpha-adrenergic agonist which may alleviate emerging symptoms in Tourette syndrome, an observation that has fueled speculation regarding involvement of stress-sensitive central noradrenergic systems in this disorder." | 7.69 | Predictors of clonidine response in Tourette syndrome: implications and inferences. ( Jackson, LA; Lichter, DG, 1996) |
| "Clonidine, an alpha 2-adrenoreceptor agonist, is useful for treating some patients with Tourette syndrome, and it has been suggested that their noradrenergic receptors are 'subsensitive'." | 7.67 | Effect of clonidine on platelet alpha 2-adrenoreceptors and plasma norepinephrine of children with Tourette syndrome. ( Johnston, MV; Silverstein, F; Smith, CB, 1985) |
| "A 15-year-old boy with Tourette's syndrome exhibited severe involuntary self-mutilatory behavior." | 5.27 | Tourette syndrome: successful treatment with clonidine and oxycodone. ( Sandyk, R, 1986) |
| "To evaluate the therapeutic effectiveness and safety of clonidine adhesive patch in treating Tourette syndrome (TS)." | 5.22 | Clinical observation on treatment of Tourette syndrome in Chinese children by clonidine adhesive patch. ( Jiao, F; Wang, J; Zhang, X, 2016) |
| "We compared the efficacy of clonidine and levetiracetam for treating tics in Tourette syndrome." | 5.14 | Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome. ( Hedderick, EF; Morris, CM; Singer, HS, 2009) |
| "The neurological disorder Gilles de la Tourette syndrome is most often treated with the receptor blocker haloperidol, which also produces multiple side-effects, including the risk for tardive dyskinesia." | 5.05 | Treatment approaches in Gilles de la Tourette syndrome. ( Ang, L; Borison, RL; Davis, JM; Diamond, BI; Hamilton, WJ, 1983) |
| " The study aimed to determine the risk of TBI in TS patients, the effects associated with concurrent psychiatric disorders (attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), or depressive disorder), and the effects of medication treatment (antipsychotics, antidepressants, or clonidine) on the risk of TBI." | 3.91 | Tourette's syndrome is associated with an increased risk of traumatic brain injury: A nationwide population-based cohort study. ( Chen, SF; Hsu, CY; Shen, YC; Su, YC; Wang, LY, 2019) |
| "Levetiracetam, an anti-epileptic agent that enhances GABAergic neurotransmission, is one of the newest alternative treatments of Tourette syndrome (TS)." | 3.74 | Levetiracetam in the treatment of antipsychotics-resistant Tourette syndrome. ( Karakatsanis, NA; Karapoulios, E; Kouzoupis, AV; Masdrakis, VG; Oulis, P; Papadimitriou, GN; Papageorgiou, C; Soldatos, CR, 2008) |
| "Atomoxetine and OROS methylphenidate were successfully used concomitantly in a 10-year-old boy suffering from attention-deficit/hyperactivity disorder (ADHD) with comorbid bipolar disorder and Tourette syndrome (TS)." | 3.73 | Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome. ( Benarroch, F; Gross-Tsur, V; Jaworowski, S, 2006) |
| " We now report that these OCD-like mice, like humans, also exhibit comorbid TS-like behaviors, including juvenile-onset tics; increased tic number, complexity and flurries; increased tic severity in males; voluntary tic suppression; and tic responsiveness to a non-cataleptic TS+OCD drug therapy (clonidine, 0." | 3.71 | A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry. ( Burton, FH; Nordstrom, EJ, 2002) |
| "Clonidine usually serves as a tic-suppressing agent in patients with Tourette syndrome." | 3.71 | Clonidine treatment increases tics in patients with Tourette syndrome: case report. ( Kessler, AR, 2001) |
| "Clonidine is an alpha-adrenergic agonist which may alleviate emerging symptoms in Tourette syndrome, an observation that has fueled speculation regarding involvement of stress-sensitive central noradrenergic systems in this disorder." | 3.69 | Predictors of clonidine response in Tourette syndrome: implications and inferences. ( Jackson, LA; Lichter, DG, 1996) |
| "Clonidine, an alpha 2-adrenoreceptor agonist, is useful for treating some patients with Tourette syndrome, and it has been suggested that their noradrenergic receptors are 'subsensitive'." | 3.67 | Effect of clonidine on platelet alpha 2-adrenoreceptors and plasma norepinephrine of children with Tourette syndrome. ( Johnston, MV; Silverstein, F; Smith, CB, 1985) |
| "For this systematic review and network meta-analysis, we searched the Cochrane Central Register of Controlled Trials, Embase, PsycINFO, PubMed, Web of Science, the WHO International Clinical Trials Registry Platform, and ClinicalTrials." | 3.01 | Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis. ( Behling, E; Bloch, MH; Farhat, LC; Landeros-Weisenberger, A; Levine, JLS; Macul Ferreira de Barros, P; Wang, Z, 2023) |
| "Children with Tourette's syndrome (TS) have a poor treatment compliance due to side effects and inconvenient administration of oral drugs." | 2.74 | [Efficacy of clonidine transdermal patch for treatment of Tourette's syndrome in children]. ( Gao, XM; Guo, XY; Jiao, FY; Kang, H; Zhang, YF, 2009) |
| " The dosage of the clonidine adhesive patch was 1." | 2.73 | Randomized double-blind multicentre placebo-controlled clinical trial of the clonidine adhesive patch for the treatment of tic disorders. ( Du, YS; Jiao, FY; Li, HF; Ma, SW; Su, LY; Vance, A; Wang, HM; Wang, MJ; Wu, JB; Yu, DL; Zhong, YQ, 2008) |
| "Nine patients with mild Tourette's syndrome completed a cross-over, placebo-controlled study of clonidine administered transdermally." | 2.67 | Treatment of Tourette's syndrome with transdermal clonidine: a pilot study. ( Angell, R; Conant-Norville, D; Gancher, S, 1990) |
| "Thirteen patients with Gilles de la Tourette's syndrome were treated with clonidine (0." | 2.66 | Short- and long-term treatment of Tourette's syndrome with clonidine: a clinical perspective. ( Cohen, DJ; Detlor, J; Harcherik, DF; Leckman, JF; Ort, S; Shaywitz, BA, 1985) |
| "Clonidine has been suggested to be effective in Gilles de la Tourette's syndrome (GTS), but no double-blind study has ever evaluated its effects using objective measures." | 2.66 | Clonidine and Gilles de la Tourette's syndrome: double-blind study using objective rating methods. ( Carroll, VS; Como, PG; Goetz, CG; Shannon, KM; Tanner, CM; Wilson, RS, 1987) |
| "Desipramine and placebo were similar on "all-cause treatment discontinuation" (RD -0." | 2.50 | Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents. ( Castells, X; Ehimare, UP; Otasowie, J; Smith, CH, 2014) |
| "Tics are repetitive and sudden purposeless movements." | 2.44 | [Diagnosis and treatment of tics]. ( Topka, H, 2007) |
| " A recent group of placebo-controlled, double-blinded clinical trials have consistently shown that certain stimulants, particularly methylphenidate and dextroamphetamine, are effective, well tolerated, and safe when administered to treat ADHD in children with tics." | 2.42 | Tourette's syndrome: are stimulants safe? ( Kurlan, R, 2003) |
| "This article reviews the evidence published in the English language literature concerning the pharmacological treatment of tics in patients with Tourette Syndrome." | 2.42 | Pharmacological management of tics in patients with TS. ( Sandor, P, 2003) |
| "Tourette's disorder is a neuropsychiatric disorder characterised clinically by motor and vocal tics, which may be associated to conductual disorders such as obsessive-compulsive disorder (OCD) and attention-deficit hyperactivity disorder (ADHD)." | 2.41 | Pharmacological options for the treatment of Tourette's disorder. ( García-Ruiz, PJ; Jiménez-Jiménez, FJ, 2001) |
| "The concept of Tourette's syndrome as a bizarre and disabling disorder has changed with greater appreciation that this is a spectrum of symptoms and degrees of severity." | 2.38 | Tics through Tourette's syndrome. ( Carter, JH, 1991) |
| "Tourette syndrome has recently been brought to public attention through popular media." | 2.37 | Tourette syndrome: a review and educational implications. ( Bauer, AM; Shea, TM, 1984) |
| "Tourette syndrome is defined and characterized mainly by the presence of motor and phonic tics." | 1.32 | Effects of medications on regulation of body temperature of patients with Tourette syndrome. ( Kessler, AR, 2004) |
| "Ganser syndrome is an uncommon disorder, particularly in children." | 1.31 | Uncomplicated Gilles de la Tourette syndrome and probable Ganser syndrome. A case report and review of the literature. ( Firth, DA; Refaat, R; Robertson, MM, 2002) |
| "Because in many patients with Tourette's syndrome (TS) the ADHD symptoms are the major source of disability, alternative nonstimulant treatments are needed." | 1.29 | Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome. ( Biederman, J; Spencer, T; Steingard, R; Wilens, T, 1993) |
| "Clonidine has been suggested as an alternative pharmacotherapy for patients with attention-deficit hyperactivity disorder (ADHD) and comorbid tic disorders." | 1.29 | Comparison of clonidine response in the treatment of attention-deficit hyperactivity disorder with and without comorbid tic disorders. ( Biederman, J; Gonzalez, A; Spencer, T; Steingard, R; Wilens, T, 1993) |
| "Clinical assessment of a child with Tourette's syndrome (TS) includes a careful review of motor and phonic tics." | 1.29 | Tourette's syndrome, Part II: Contemporary approaches to assessment and treatment. ( Hardin, MT; Ort, SI; Scahill, L, 1993) |
| "A 7-year-old boy with Tourette's disorder, atypical pervasive developmental disorder, borderline mental retardation, and a history of self-injurious behavior was treated for 21 months with clonidine transdermal patches at doses ranging from 0." | 1.28 | Self-injurious behavior associated with clonidine withdrawal in a child with Tourette's disorder. ( Dillon, JE, 1990) |
| "This paper describes an attempt to treat Gilles de la Tourette syndrome (GTS) in a severely mentally handicapped girl, using a cue-controlled relaxation technique." | 1.28 | A behavioural intervention for Gilles de la Tourette syndrome in a severely mentally handicapped girl. ( Crawley, B; Locke, J; Zarkowska, E, 1989) |
| "A diagnosis of Tourette's syndrome was made, and when family objected to a trial of haloperidol for fear of tardive dyskinesia, clonidine was initiated." | 1.28 | Transient exacerbation of tics in treatment of Tourette's syndrome with clonidine. ( Huk, SG, 1989) |
| "Tourette syndrome is a neuropsychiatric disorder of motor and vocal tics, with associated symptoms of obsessive-compulsive behaviors and attention deficit disorder with hyperactivity." | 1.27 | [The treatment of children with Gilles de la Tourette's syndrome]. ( Minderaa, RB, 1987) |
| "Compared to 87 normal controls, Tourette's disorder patients had lower mean baseline WBTRP levels (mean +/- SEM: Tourette's, 5993 +/- 304 ng/ml vs." | 1.27 | Whole blood serotonin and tryptophan levels in Tourette's disorder: effects of acute and chronic clonidine treatment. ( Anderson, GM; Cohen, DJ; Harcherik, DF; Hoder, EL; Leckman, JF; Ort, S; Shaywitz, BA, 1984) |
| "Gilles de la Tourette's syndrome (GTS) is a chronic neuropsychiatric disorder characterized by multiple involuntary motor and phonic tics associated with behavioural disturbances including obsessive-compulsive and aggressive behavior, depression and, rarely, psychosis." | 1.27 | Beneficial effects of imipramine on Tourette's syndrome. ( Bamford, CR; Sandyk, R, 1988) |
| "A patient with long-standing Tourette's syndrome had a dramatic exacerbation of symptoms following the rapid withdrawal of haloperidol." | 1.27 | Clonidine in the treatment of Tourette's syndrome exacerbation due to haloperidol withdrawal. ( Max, JE; Rasmussen, SA, 1986) |
| "Twenty-three patients with Gilles de la Tourette's syndrome (GTS) underwent noninvasive investigation of autonomic nervous system (ANS) function, as did 23 age-matched controls." | 1.27 | The autonomic nervous system in Gilles de la Tourette's syndrome. ( Carroll, VS; Goetz, CG; Shannon, KM; Tanner, CM; Weingarten, R, 1987) |
| "A 15-year-old boy with Tourette's syndrome exhibited severe involuntary self-mutilatory behavior." | 1.27 | Tourette syndrome: successful treatment with clonidine and oxycodone. ( Sandyk, R, 1986) |
| "Pimozide was used as the preferred drug because of our experience of treating other hyperkinesias which indicated fewer side-effects than with haloperidol." | 1.27 | Clinical features and long-term treatment with pimozide in 65 patients with Gilles de la Tourette's syndrome. ( Fog, R; Pakkenberg, B; Pakkenberg, H; Regeur, L, 1986) |
| "Clonidine's effectiveness in Tourette's syndrome may be dependent on changes in dopaminergic as well as adrenergic mechanisms." | 1.27 | Rebound phenomena in Tourette's syndrome after abrupt withdrawal of clonidine. Behavioral, cardiovascular, and neurochemical effects. ( Anderson, GM; Caruso, KA; Cohen, DJ; Leckman, JF; Ort, S; Riddle, MA, 1986) |
| "Over 86% of 58 patients with Gilles de la Tourette's syndrome achieved effective pharmacologic control of the symptoms for 3 months or longer." | 1.27 | Treatment of Gilles de la Tourette's syndrome: eight-year, practice-based experience in a predominantly adult population. ( Mesulam, MM; Petersen, RC, 1987) |
| "Successful treatment of Tourette's syndrome in a young man seemed to precipitate anorexia nervosa." | 1.27 | Anorexia nervosa in a young man with Tourette's syndrome. ( Annibali, JA; Kales, JD; Tan, TL, 1986) |
| "A 25-year-old woman with Gilles de la Tourette's disease was successfully treated with clonidine (an inhibitor of noradrenaline release)." | 1.26 | On the use of clonidine and thioproperazine in a woman with Gilles de la Tourette's disease. ( Acosta, E; Arocha, L; Gómez, F; Lechin, F; van der Dijs, B, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (55.36) | 18.7374 |
| 1990's | 22 (19.64) | 18.2507 |
| 2000's | 20 (17.86) | 29.6817 |
| 2010's | 7 (6.25) | 24.3611 |
| 2020's | 1 (0.89) | 2.80 |
| Authors | Studies |
|---|---|
| Farhat, LC | 2 |
| Behling, E | 2 |
| Landeros-Weisenberger, A | 2 |
| Levine, JLS | 2 |
| Macul Ferreira de Barros, P | 2 |
| Wang, Z | 2 |
| Bloch, MH | 2 |
| Chen, SF | 1 |
| Su, YC | 1 |
| Wang, LY | 1 |
| Hsu, CY | 1 |
| Shen, YC | 1 |
| Eapen, V | 1 |
| Ward, P | 1 |
| Clarke, R | 1 |
| Otasowie, J | 1 |
| Castells, X | 1 |
| Ehimare, UP | 1 |
| Smith, CH | 1 |
| Jiao, F | 1 |
| Zhang, X | 2 |
| Wang, J | 1 |
| Du, YS | 1 |
| Li, HF | 1 |
| Vance, A | 1 |
| Zhong, YQ | 1 |
| Jiao, FY | 2 |
| Wang, HM | 1 |
| Wang, MJ | 1 |
| Su, LY | 1 |
| Yu, DL | 1 |
| Ma, SW | 1 |
| Wu, JB | 1 |
| Hedderick, EF | 1 |
| Morris, CM | 1 |
| Singer, HS | 3 |
| Kang, H | 1 |
| Zhang, YF | 1 |
| Guo, XY | 1 |
| Gao, XM | 1 |
| Rickards, H | 1 |
| Cavanna, AE | 1 |
| Worrall, R | 1 |
| Pringsheim, T | 2 |
| Doja, A | 1 |
| Gorman, D | 1 |
| McKinlay, D | 1 |
| Day, L | 1 |
| Billinghurst, L | 1 |
| Carroll, A | 1 |
| Dion, Y | 1 |
| Luscombe, S | 1 |
| Steeves, T | 1 |
| Sandor, P | 2 |
| Nordstrom, EJ | 1 |
| Burton, FH | 1 |
| Suchard, JR | 1 |
| Graeme, KA | 1 |
| Levenson, D | 1 |
| Refaat, R | 1 |
| Firth, DA | 1 |
| Robertson, MM | 1 |
| Stewart, JT | 1 |
| Williams, LS | 1 |
| Kurlan, R | 1 |
| Kano, Y | 1 |
| Kessler, AR | 2 |
| Jaworowski, S | 1 |
| Benarroch, F | 1 |
| Gross-Tsur, V | 1 |
| Kotcher, L | 1 |
| Wieland, N | 1 |
| Coffey, B | 1 |
| Topka, H | 1 |
| Oulis, P | 1 |
| Karapoulios, E | 1 |
| Masdrakis, VG | 1 |
| Kouzoupis, AV | 1 |
| Karakatsanis, NA | 1 |
| Papageorgiou, C | 1 |
| Papadimitriou, GN | 1 |
| Soldatos, CR | 1 |
| McNicholas, F | 1 |
| Motala, F | 1 |
| Dysken, MW | 1 |
| Berecz, JM | 1 |
| Samarza, A | 1 |
| Davis, JM | 3 |
| McKeith, IG | 1 |
| Williams, A | 1 |
| Nicol, AR | 1 |
| Lechin, F | 1 |
| van der Dijs, B | 1 |
| Gómez, F | 1 |
| Acosta, E | 1 |
| Arocha, L | 1 |
| Shapiro, AK | 4 |
| Shapiro, E | 4 |
| Eisenkraft, GJ | 1 |
| Golden, GS | 1 |
| Gillies, DR | 1 |
| Forsythe, WI | 1 |
| van Woert, MH | 1 |
| Rosenbaum, D | 1 |
| Enna, SJ | 1 |
| Selinger, D | 1 |
| Cohen, DJ | 18 |
| Ort, S | 6 |
| Anderson, GM | 6 |
| Caruso, KA | 3 |
| Leckman, JF | 13 |
| Detlor, J | 5 |
| Young, JG | 5 |
| Shaywitz, BA | 10 |
| Bauer, AM | 1 |
| Shea, TM | 1 |
| Borison, RL | 2 |
| Ang, L | 2 |
| Hamilton, WJ | 1 |
| Diamond, BI | 1 |
| Harcherik, DF | 4 |
| Terkelsen, KG | 1 |
| Bruun, RD | 2 |
| Gertner, JM | 1 |
| Fennig, S | 1 |
| Bauer, A | 1 |
| Kronnenberg, Y | 1 |
| Hoder, EL | 1 |
| Chang, S | 1 |
| Dysken, M | 1 |
| Comaty, JE | 1 |
| Harcherik, D | 1 |
| Dorsey, R | 1 |
| Hattox, SE | 1 |
| Kavanagh, ME | 1 |
| Maas, JW | 1 |
| Dupont, E | 1 |
| Nørgaard, B | 1 |
| Ferre, RC | 1 |
| Wolf, A | 1 |
| Shaywitz, SE | 1 |
| Loomis, R | 1 |
| Pakkenberg, B | 2 |
| Regeur, L | 2 |
| Fog, R | 2 |
| Pakkenberg, H | 2 |
| Whelan, R | 1 |
| Dearlove, OR | 1 |
| Brown, J | 1 |
| Quaskey, S | 1 |
| Rosenberg, LA | 1 |
| Mellits, ED | 1 |
| Denckla, MB | 1 |
| Walkup, JT | 1 |
| Scahill, LD | 1 |
| Riddle, MA | 4 |
| Como, PG | 2 |
| Müller, N | 1 |
| Putz, A | 1 |
| Klages, U | 1 |
| Hofschuster, E | 1 |
| Straube, A | 1 |
| Ackenheil, M | 1 |
| Scahill, L | 1 |
| Ort, SI | 2 |
| Hardin, MT | 2 |
| Spencer, T | 3 |
| Biederman, J | 3 |
| Wilens, T | 3 |
| Steingard, R | 3 |
| Geist, D | 1 |
| Gonzalez, A | 1 |
| Lichter, DG | 1 |
| Jackson, LA | 1 |
| Weaver, A | 1 |
| Peterson, BS | 1 |
| Holmes, TS | 1 |
| Jiménez-Jiménez, FJ | 1 |
| García-Ruiz, PJ | 1 |
| Gaffney, GR | 1 |
| Perry, PJ | 1 |
| Lund, BC | 1 |
| Bever-Stille, KA | 1 |
| Arndt, S | 1 |
| Kuperman, S | 1 |
| Nathanson, JA | 1 |
| Goetz, CG | 4 |
| Vink, HJ | 1 |
| Althaus, M | 1 |
| Goorhuis-Brouwer, SM | 1 |
| Minderaa, RB | 4 |
| Carter, JH | 1 |
| Stevenson, J | 1 |
| Gancher, S | 1 |
| Conant-Norville, D | 1 |
| Angell, R | 1 |
| Dillon, JE | 1 |
| Comings, DE | 1 |
| Comings, BG | 1 |
| Tacket, T | 1 |
| Li, SZ | 1 |
| Zarkowska, E | 1 |
| Crawley, B | 1 |
| Locke, J | 1 |
| Huk, SG | 1 |
| Caine, ED | 2 |
| Munetz, MR | 1 |
| Slawsky, RC | 1 |
| Neil, JF | 1 |
| Sandyk, R | 3 |
| Svensson, TH | 1 |
| Jankovic, J | 1 |
| van de Wetering, BJ | 2 |
| Cohen, AP | 2 |
| Roos, RA | 2 |
| van Woerkom, TC | 2 |
| Shannon, KM | 3 |
| Carroll, VS | 2 |
| Tanner, CM | 3 |
| Weingarten, R | 1 |
| Silverstein, F | 1 |
| Smith, CB | 1 |
| Johnston, MV | 1 |
| Hunt, RD | 1 |
| Kremenitzer, M | 1 |
| McBride, MC | 1 |
| Chiverton, P | 1 |
| Bamford, KA | 1 |
| Rediess, S | 1 |
| Shiao, J | 1 |
| Bamford, CR | 1 |
| Erenberg, G | 2 |
| Wilson, RS | 2 |
| Max, JE | 1 |
| Rasmussen, SA | 1 |
| Annibali, JA | 1 |
| Kales, JD | 1 |
| Tan, TL | 1 |
| Kerbeshian, J | 1 |
| Burd, L | 1 |
| Cruse, RP | 1 |
| Rothner, AD | 1 |
| Mesulam, MM | 1 |
| Petersen, RC | 1 |
| Miller, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Behavioral Therapy for Children and Adolescents With Tourette Syndrome: A Randomized Controlled Trial in Taiwan[NCT03621059] | 46 participants (Actual) | Interventional | 2015-01-01 | Completed | |||
| Finalizing and Testing an Online Therapist Training and Assistance Program to Facilitate Implementation of Comprehensive Behavioral Intervention for Tic Disorders[NCT05547854] | 234 participants (Anticipated) | Interventional | 2023-06-27 | Recruiting | |||
| [NCT00004325] | 200 participants | Observational | 1988-12-31 | Completed | |||
| Transcranial Magnetic Stimulation for Individuals With Tourette's Syndrome[NCT00529308] | Phase 2 | 20 participants (Actual) | Interventional | 2007-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"The CGI-I is a clinician-rated scales that have been used in clinical trials for over 25 years. Clinicians rate patient improvement compared to baseline. By convention, 4 = No Change; scores of 5, 6, and 7 move in the direction of worsening; scores of 3, 2, and 1 correspond to Minimal Improvement, Much Improved or Very Much Improved, respectively. CGI-I ratings of Much or Very Much Improved at post-treatment are used to identify treatment responders." (NCT00529308)
Timeframe: 3 weeks
| Intervention | participants (Number) |
|---|---|
| Active | 2 |
| Sham | 8 |
"The CGI-I is a clinician-rated scales that have been used in clinical trials for over 25 years. Clinicians rate patient improvement compared to baseline. By convention, 4 = No Change; scores of 5, 6, and 7 move in the direction of worsening; scores of 3, 2, and 1 correspond to Minimal Improvement, Much Improved or Very Much Improved, respectively. CGI-I ratings of Much or Very Much Improved at post-treatment are used to identify treatment responders." (NCT00529308)
Timeframe: 3 weeks
| Intervention | participants (Number) |
|---|---|
| Active | 1 |
| Sham | 0 |
Motor Threshold (MT) is thought to be a measure of membrane excitability in pyramidal neurons. MT is defined as the minimum magnetic flux needed to elicit a threshold EMG response (50 µV in peak to peak amplitude) in a resting target muscle in 5 out of 10 trials using single pulse TMS administered to the contralateral primary motor cortex. MT for both right and left hand are determined, and the lowest is used to select the intensity for rTMS. (NCT00529308)
Timeframe: 3 weeks
| Intervention | µV (Mean) |
|---|---|
| Active | 56.5 |
| Sham | 63.8 |
Motor Threshold (MT) is thought to be a measure of membrane excitability in pyramidal neurons. MT is defined as the minimum magnetic flux needed to elicit a threshold EMG response (50 µV in peak to peak amplitude) in a resting target muscle in 5 out of 10 trials using single pulse TMS administered to the contralateral primary motor cortex. MT for both right and left hand are determined, and the lowest is used to select the intensity for rTMS. (NCT00529308)
Timeframe: 3 weeks
| Intervention | µV (Mean) |
|---|---|
| Active | 56 |
| Sham | 59.8 |
Y-GTSS is a clinician-rated scale used to assess tic severity. Motor and phonic tics are rated separately from 0 to 5 on several scales including number, frequency, intensity, complexity, and interference. Thus Motor and Phonic Tic scores can range from 0 to 25; the combined Total Tic Score ranges from 0 to 50. There is also an Impairment score that rates the overall burden due to tics. The Impairment scale yields a single score from 0 to 50 with higher scores indicating higher levels of overall impairment associated with tics. (NCT00529308)
Timeframe: 3 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Active | 29.5 |
| Sham | 31.5 |
22 reviews available for clonidine and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi | 2023 |
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi | 2023 |
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi | 2023 |
Comparative efficacy, tolerability, and acceptability of pharmacological interventions for the treatment of children, adolescents, and young adults with Tourette's syndrome: a systematic review and network meta-analysis.
Topics: Adolescent; Adrenergic alpha-2 Receptor Agonists; Antipsychotic Agents; Aripiprazole; Child; Clonidi | 2023 |
Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Central | 2014 |
Canadian guidelines for the evidence-based treatment of tic disorders: pharmacotherapy.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Antipsychotic Agents; Canada; Child; Clonidine; Evidenc | 2012 |
Pharmacological management of tics in patients with TS.
Topics: Anti-Dyskinesia Agents; Antipsychotic Agents; Clonidine; Dopamine Antagonists; Haloperidol; Humans; | 2003 |
Tourette's syndrome: are stimulants safe?
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Clinical | 2003 |
[Chronic tic disorders--chronic mortor or vocal tic disorders and de la Tourette's syndrome].
Topics: Adolescent; Antidepressive Agents; Attention Deficit Disorder with Hyperactivity; Central Nervous Sy | 2003 |
[Diagnosis and treatment of tics].
Topics: Adolescent; Adult; Age Factors; Antipsychotic Agents; Child; Child, Preschool; Chronic Disease; Clin | 2007 |
Treatment of multiple tics and the Tourette syndrome.
Topics: Adolescent; Antipsychotic Agents; Benztropine; Child; Child, Preschool; Clonidine; Haloperidol; Huma | 1984 |
Recent advances in Gilles de la Tourette syndrome: implications for clinical practice and future research.
Topics: Adolescent; Age Factors; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Compulsive | 1983 |
Tourette syndrome: a review and educational implications.
Topics: Adolescent; Child; Child, Preschool; Clonidine; Education, Special; Female; Haloperidol; Humans; Mal | 1984 |
Disruptive behavior, hyperactivity, and learning disabilities in children with Tourette's syndrome.
Topics: Adolescent; Antidepressive Agents, Tricyclic; Attention Deficit Disorder with Hyperactivity; Child; | 1995 |
Obsessive-compulsive disorder in Tourette's syndrome.
Topics: Behavior Therapy; Clomipramine; Clonidine; Fluvoxamine; Humans; Obsessive-Compulsive Disorder; Toure | 1995 |
Tic disorders.
Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Behavior Therapy; Child; Child | 1993 |
The treatment of Tourette's syndrome: multimodal, developmental intervention.
Topics: Adaptation, Psychological; Adolescent; Adrenergic Agonists; Adult; Age Factors; Antidepressive Agent | 1998 |
Pharmacological options for the treatment of Tourette's disorder.
Topics: Adrenergic alpha-Agonists; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Botulinum | 2001 |
Clonidine and clonazepam in Tourette syndrome.
Topics: Clonazepam; Clonidine; Humans; Tourette Syndrome | 1992 |
Pharmacotherapy of Tourette's syndrome and associated disorders.
Topics: Attention Deficit Disorder with Hyperactivity; Clonidine; Female; Haloperidol; Humans; Male; Mental | 1992 |
Tics through Tourette's syndrome.
Topics: Antipsychotic Agents; Clonidine; Counseling; Humans; Nursing Assessment; Self-Help Groups; Tourette | 1991 |
Gilles de la Tourette's syndrome. A review of clinical and research studies and consideration of future directions for investigation.
Topics: Adolescent; Adult; Animals; Behavior Therapy; Brain; Child; Child, Preschool; Clinical Trials as Top | 1985 |
The endogenous opioid system in neurological disorders of the basal ganglia.
Topics: Animals; Antipsychotic Agents; Basal Ganglia Diseases; Clonidine; Endorphins; gamma-Aminobutyric Aci | 1985 |
Clonidine in abstinence reactions: basic mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Anxiety Disorders; Autonomic Nervous System; Central Nervous Sys | 1986 |
Recent advances in the management of tics.
Topics: Antipsychotic Agents; Clonidine; Humans; Receptors, Dopamine; Tic Disorders; Tourette Syndrome | 1986 |
19 trials available for clonidine and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Clinical observation on treatment of Tourette syndrome in Chinese children by clonidine adhesive patch.
Topics: Antipsychotic Agents; Asian People; Blood Pressure; Child; Child, Preschool; Clonidine; Female; Halo | 2016 |
Randomized double-blind multicentre placebo-controlled clinical trial of the clonidine adhesive patch for the treatment of tic disorders.
Topics: Administration, Cutaneous; Adolescent; Adrenergic alpha-Agonists; Child; China; Clonidine; Dose-Resp | 2008 |
Double-blind, crossover study of clonidine and levetiracetam in Tourette syndrome.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Child; Clonidine; Confidence Intervals; Cross-Sectiona | 2009 |
[Efficacy of clonidine transdermal patch for treatment of Tourette's syndrome in children].
Topics: Administration, Cutaneous; Adolescent; Child; Child, Preschool; Clonidine; Female; Haloperidol; Huma | 2009 |
Clonidine in Tourette syndrome.
Topics: Adult; Age Factors; Clinical Trials as Topic; Clonidine; Humans; Tourette Syndrome | 1980 |
Clonidine in Tourette syndrome.
Topics: Adolescent; Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; Male; Tourette Syndrom | 1981 |
Treatment of Gilles de la Tourette's syndrome with clonidine and neuroleptics.
Topics: Adult; Antipsychotic Agents; Attitude to Health; Clinical Trials as Topic; Clonidine; Drug Therapy, | 1983 |
Treatment approaches in Gilles de la Tourette syndrome.
Topics: Amantadine; Benztropine; Clonidine; Fluphenazine; Haloperidol; Humans; Lithium; Tourette Syndrome; T | 1983 |
New pharmacological approaches in the treatment of Tourette syndrome.
Topics: Adolescent; Adult; Amantadine; Benztropine; Child; Clinical Trials as Topic; Clonidine; Female; Flup | 1982 |
Clonidine in the treatment of Tourette syndrome: a review of data.
Topics: Adolescent; Biomechanical Phenomena; Blood Pressure; Clinical Trials as Topic; Clonidine; Dopamine; | 1982 |
The treatment of attention-deficit hyperactivity disorder in Tourette's syndrome: a double-blind placebo-controlled study with clonidine and desipramine.
Topics: Adolescent; Analysis of Variance; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; D | 1995 |
Risperidone versus clonidine in the treatment of children and adolescents with Tourette's syndrome.
Topics: Adrenergic alpha-Agonists; Antipsychotic Agents; Child; Clonidine; Double-Blind Method; Female; Huma | 2002 |
Clonidine and stuttering.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Female; Humans; Male; S | 1992 |
Clonidine treatment of Gilles de la Tourette's syndrome.
Topics: Administration, Oral; Adolescent; Adult; Clonidine; Double-Blind Method; Drug Administration Schedul | 1991 |
Treatment of Tourette's syndrome with transdermal clonidine: a pilot study.
Topics: Administration, Cutaneous; Adult; Child; Clonidine; Drug Administration Schedule; Female; Humans; Ma | 1990 |
Gilles de la Tourette's syndrome. A review of clinical and research studies and consideration of future directions for investigation.
Topics: Adolescent; Adult; Animals; Behavior Therapy; Brain; Child; Child, Preschool; Clinical Trials as Top | 1985 |
Clonidine and Gilles de la Tourette's syndrome: double-blind study using objective rating methods.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Humans; | 1987 |
Clonidine in Gilles de la Tourette's syndrome.
Topics: Clinical Trials as Topic; Clonidine; Double-Blind Method; Humans; Tourette Syndrome | 1987 |
Short- and long-term treatment of Tourette's syndrome with clonidine: a clinical perspective.
Topics: Adolescent; Behavior; Child; Clinical Trials as Topic; Clonidine; Disability Evaluation; Female; Hum | 1985 |
72 other studies available for clonidine and Chronic Motor and Vocal Tic Disorder
| Article | Year |
|---|---|
Tourette's syndrome is associated with an increased risk of traumatic brain injury: A nationwide population-based cohort study.
Topics: Adolescent; Adult; Antidepressive Agents; Antipsychotic Agents; Attention Deficit Disorder with Hype | 2019 |
Clonidine in Tourette syndrome and sensorimotor gating.
Topics: Adrenergic alpha-2 Receptor Agonists; Clonidine; Humans; Sensory Gating; Tourette Syndrome | 2014 |
Treatment practices in Tourette syndrome: the European perspective.
Topics: Adult; Antidepressive Agents; Antipsychotic Agents; Anxiety; Aripiprazole; Atomoxetine Hydrochloride | 2012 |
Psychopharmacology for the clinician: management of comorbid Tourette syndrome and attention-deficit/hyperactivity disorder: are psychostimulants an option?
Topics: Adrenergic alpha-2 Receptor Agonists; Attention Deficit Disorder with Hyperactivity; Central Nervous | 2012 |
A transgenic model of comorbid Tourette's syndrome and obsessive-compulsive disorder circuitry.
Topics: Analgesics; Animals; Cholera Toxin; Clonidine; Comorbidity; Female; Incidence; Male; Mice; Mice, Tra | 2002 |
Pediatric clonidine poisoning as a result of pharmacy compounding error.
Topics: Adrenergic alpha-Agonists; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Drug Com | 2002 |
Ritalin is okay for kids with both ADHD and Tourette's syndrome, study says.
Topics: Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Clinical Tr | 2002 |
Uncomplicated Gilles de la Tourette syndrome and probable Ganser syndrome. A case report and review of the literature.
Topics: Adolescent; Clonidine; Diagnosis, Differential; Factitious Disorders; Female; Humans; Sympatholytics | 2002 |
Tourette's-like syndrome and dementia.
Topics: Aged; Clonidine; Comorbidity; Dementia; Humans; Male; Tourette Syndrome | 2003 |
Effects of medications on regulation of body temperature of patients with Tourette syndrome.
Topics: Adolescent; Adult; Body Temperature Regulation; Child; Child, Preschool; Circadian Rhythm; Clonidine | 2004 |
Concomitant use of atomoxetine and OROS-methylphenidate in a 10-year-old child suffering from attention-deficit/hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome.
Topics: Adrenergic Uptake Inhibitors; Atomoxetine Hydrochloride; Attention Deficit Disorder with Hyperactivi | 2006 |
Trichotillomania and co-morbid psychiatric disorders in a 10-year-old boy.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comorbidity; Drug Therapy, Combinat | 2007 |
Levetiracetam in the treatment of antipsychotics-resistant Tourette syndrome.
Topics: Adrenergic alpha-Agonists; Adult; Anti-Dyskinesia Agents; Anticonvulsants; Antipsychotic Agents; Clo | 2008 |
Transient ischemic attack with risperidone and clonidine.
Topics: Adrenergic alpha-Agonists; Antipsychotic Agents; Child; Clonidine; Diagnosis, Differential; Drug Adm | 2007 |
On the use of clonidine and thioproperazine in a woman with Gilles de la Tourette's disease.
Topics: Adult; Clonidine; Female; Gastrointestinal Motility; Humans; Phenothiazines; Receptors, Adrenergic; | 1982 |
Psychologic and neuropsychologic aspects of Tourette's syndrome.
Topics: Achievement; Adolescent; Adult; Attention; Central Nervous System Stimulants; Child; Clonidine; Halo | 1984 |
Overview of pharmacological approaches to therapy for Tourette syndrome.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antipsychotic Agents; Child; Clonidine; Corpus Striatum; Fem | 1982 |
Parotid salivary response to clonidine in Tourette's syndrome: indicator of adrenergic responsivity.
Topics: Adolescent; Adult; Amylases; Child; Clonidine; Humans; Parotid Gland; Receptors, Adrenergic; Salivat | 1984 |
Clonidine ameliorates Gilles de la Tourette syndrome.
Topics: Adolescent; Adult; Child; Clonidine; Dose-Response Relationship, Drug; Drug Administration Schedule; | 1980 |
Acute and chronic clonidine treatment in Tourette's syndrome: a preliminary report on clinical response and effect on plasma and urinary catecholamine metabolites, growth hormone, and blood pressure.
Topics: Adolescent; Blood Pressure; Catecholamines; Child; Clonidine; Double-Blind Method; Growth Hormone; H | 1983 |
Mania after surreptitious discontinuation of clonidine.
Topics: Bipolar Disorder; Clonidine; Humans; Patient Compliance; Substance Withdrawal Syndrome; Tourette Syn | 1984 |
Tourette's syndrome: advances in treatment and research.
Topics: Child; Clonidine; Haloperidol; Humans; Pimozide; Tourette Syndrome | 1984 |
Gilles de la Tourette's syndrome. An overview of clinical experience.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Clonidine; Compu | 1984 |
Growth hormone response to clonidine in children ages 4-17: Tourette's syndrome vs. children with short stature.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Body Height; Child; Child, Preschool; Clo | 1984 |
[Treatment of Gilles de la Tourette Syndrome with haloperidol and clonidine].
Topics: Adolescent; Child; Clonidine; Drug Synergism; Drug Therapy, Combination; Haloperidol; Humans; Male; | 1984 |
Whole blood serotonin and tryptophan levels in Tourette's disorder: effects of acute and chronic clonidine treatment.
Topics: Adolescent; Adult; Child; Clonidine; Humans; Middle Aged; Receptors, Adrenergic; Serotonin; Tourette | 1984 |
Tourette syndrome: history and present status.
Topics: Aging; Clonidine; Demography; Ethnicity; Forecasting; Haloperidol; History, 15th Century; History, 1 | 1982 |
Neuropsychopharmacology of clonidine-clinical studies.
Topics: Clonidine; Emotions; Humans; Mental Disorders; Nervous System; Panic; Psychotropic Drugs; Tourette S | 1981 |
Clonidine and haloperidol in Gilles de la Tourette syndrome.
Topics: Clonidine; Haloperidol; Humans; Tourette Syndrome | 1981 |
Clonidine and Gilles de la Tourette syndrome.
Topics: Adolescent; Adult; Child; Clonidine; Humans; Tourette Syndrome | 1981 |
Plasma free MHPG and neuroendocrine responses to challenge doses of clonidine in Tourette's syndrome: preliminary report.
Topics: Adolescent; Adult; Child; Clonidine; Endocrine Glands; Glycols; Growth Hormone; Humans; Hydrocortiso | 1981 |
[Multiple tics in children and adults. Tourette's syndrome].
Topics: Adolescent; Adult; Age Factors; Aged; Clonidine; Female; Haloperidol; Humans; Male; Tourette Syndrom | 1982 |
Tourette's disorder and the use of clonidine.
Topics: Adolescent; Clonidine; Humans; Male; Psychotherapy; Tourette Syndrome | 1982 |
Animal models of neuropsychiatric disorders and their relevance for Tourette syndrome.
Topics: Animals; Attention Deficit Disorder with Hyperactivity; Clonidine; Disease Models, Animal; Dopamine; | 1982 |
Interaction of biological and psychological factors in the natural history of Tourette syndrome: a paradigm for childhood neuropsychiatric disorders.
Topics: Adolescent; Adult; Attention; Behavior; Biomechanical Phenomena; Child; Child, Preschool; Clonidine; | 1982 |
Clinical efficacy of haloperidol, pimozide, penfluridol, and clonidine in the treatment of tourette syndrome.
Topics: Child; Child, Preschool; Clonidine; Haloperidol; Humans; Penfluridol; Pimozide; Piperidines; Tourett | 1982 |
Clonidine treatment of Tourette syndrome.
Topics: Adolescent; Adult; Child; Clonidine; Female; Haloperidol; Humans; Male; Outcome and Process Assessme | 1982 |
[Gilles de la Tourette's syndrome. Experiences with 18 patients].
Topics: Adolescent; Adult; Child; Clonidine; Female; Humans; Male; Pimozide; Tetrabenazine; Tourette Syndrom | 1982 |
Management of clonidine overdose in a child with Tourette syndrome.
Topics: Child; Chlorpromazine; Clonidine; Drug Overdose; Humans; Male; Suicide, Attempted; Tourette Syndrome | 1995 |
Blunted growth hormone response to clonidine in Gilles de la Tourette syndrome.
Topics: Adult; Clonidine; Female; Growth Hormone; Humans; Male; Norepinephrine; Radioimmunoassay; Receptors, | 1994 |
Tourette's syndrome, Part II: Contemporary approaches to assessment and treatment.
Topics: Adolescent; Adult; Child; Clonidine; Combined Modality Therapy; Education, Special; Female; Haloperi | 1993 |
Nortriptyline treatment of children with attention-deficit hyperactivity disorder and tic disorder or Tourette's syndrome.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comorbidity; Family Hea | 1993 |
Bupropion exacerbates tics in children with attention-deficit hyperactivity disorder and Tourette's syndrome.
Topics: Attention Deficit Disorder with Hyperactivity; Bupropion; Child; Clonidine; Desipramine; Female; Hum | 1993 |
Comparison of clonidine response in the treatment of attention-deficit hyperactivity disorder with and without comorbid tic disorders.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child, Preschool; Clonidine; Comor | 1993 |
Predictors of clonidine response in Tourette syndrome: implications and inferences.
Topics: Adolescent; Adrenergic alpha-Agonists; Age Factors; Attention Deficit Disorder with Hyperactivity; C | 1996 |
Attention deficit disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Comorbidity; Humans; Psychotropic D | 1996 |
Conflicting and inconsistent dosing advice for clonidine in Tourette's syndrome.
Topics: Administration, Cutaneous; Administration, Oral; Antipsychotic Agents; Clonidine; Drug Administratio | 1998 |
Clonidine treatment increases tics in patients with Tourette syndrome: case report.
Topics: Adrenergic alpha-Agonists; Child; Clonidine; Humans; Male; Tics; Tourette Syndrome | 2001 |
Clonidine in Tourette's syndrome.
Topics: Adolescent; Blood Pressure; Child; Clonidine; Drug Tolerance; Female; Humans; Male; Tourette Syndrom | 1979 |
Self-injurious behavior associated with clonidine withdrawal in a child with Tourette's disorder.
Topics: Arousal; Child; Clonidine; Humans; Male; Motor Activity; Self Mutilation; Substance Withdrawal Syndr | 1990 |
The clonidine patch and behavior problems.
Topics: Administration, Cutaneous; Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Child B | 1990 |
A behavioural intervention for Gilles de la Tourette syndrome in a severely mentally handicapped girl.
Topics: Adolescent; Behavior Therapy; Clonidine; Combined Modality Therapy; Cues; Education of Intellectuall | 1989 |
Transient exacerbation of tics in treatment of Tourette's syndrome with clonidine.
Topics: Child; Clonidine; Dose-Response Relationship, Drug; Humans; Male; Tourette Syndrome | 1989 |
Tardive Tourette's syndrome treated with clonidine and mesoridazine.
Topics: Antipsychotic Agents; Clonidine; Female; Humans; Mesoridazine; Middle Aged; Tourette Syndrome | 1985 |
[The treatment of children with Gilles de la Tourette's syndrome].
Topics: Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Haloperidol; | 1987 |
[Gilles de la Tourette syndrome].
Topics: Adolescent; Adult; Antipsychotic Agents; Child; Clonidine; Compulsive Behavior; Female; Humans; Male | 1988 |
The autonomic nervous system in Gilles de la Tourette's syndrome.
Topics: Adolescent; Adult; Antipsychotic Agents; Autonomic Nervous System; Clonidine; Drug Therapy, Combinat | 1987 |
Effect of clonidine on platelet alpha 2-adrenoreceptors and plasma norepinephrine of children with Tourette syndrome.
Topics: Blood Platelets; Child; Clonidine; Humans; Kinetics; Male; Norepinephrine; Radioligand Assay; Recept | 1985 |
Parotid gland salivary secretion in Tourette's syndrome and attention deficit disorder: a model system for the study of neurochemical regulation.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Clonidine; Female; Humans; Male; P | 1987 |
Tourette's syndrome in Monroe County school children.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Behavior; Child; Child, Preschool; Clonid | 1988 |
Beneficial effects of imipramine on Tourette's syndrome.
Topics: Child; Clonidine; Female; Haloperidol; Humans; Imipramine; Tourette Syndrome | 1988 |
Pharmacologic therapy of tics in childhood.
Topics: Adolescent; Adult; Child; Clonazepam; Clonidine; Haloperidol; Humans; Pimozide; Tic Disorders; Toure | 1988 |
Clonidine in the treatment of Tourette's syndrome exacerbation due to haloperidol withdrawal.
Topics: Acute Disease; Adult; Clonidine; Haloperidol; Humans; Male; Substance Withdrawal Syndrome; Tourette | 1986 |
Anorexia nervosa in a young man with Tourette's syndrome.
Topics: Adolescent; Age Factors; Anorexia Nervosa; Clonidine; Humans; Male; Obsessive Behavior; Psychotherap | 1986 |
Tourette syndrome: successful treatment with clonidine and oxycodone.
Topics: Adolescent; Clonidine; Codeine; Drug Therapy, Combination; Humans; Male; Oxycodone; Tourette Syndrom | 1986 |
Clinical features and long-term treatment with pimozide in 65 patients with Gilles de la Tourette's syndrome.
Topics: Adolescent; Adult; Child; Clonidine; Drug Therapy, Combination; Electroencephalography; Female; Huma | 1986 |
Rebound phenomena in Tourette's syndrome after abrupt withdrawal of clonidine. Behavioral, cardiovascular, and neurochemical effects.
Topics: Adolescent; Blood Pressure; Child; Clonidine; Epinephrine; Homovanillic Acid; Humans; Male; Methoxyh | 1986 |
Novel side effects of clonidine in the treatment of Tourette disorder.
Topics: Adolescent; Clonidine; Female; Humans; Tourette Syndrome | 1987 |
A rating scale for Gilles de la Tourette's syndrome: description, reliability, and validity data.
Topics: Clonidine; Double-Blind Method; Humans; Tourette Syndrome | 1987 |
The natural history of Tourette syndrome: a follow-up study.
Topics: Adaptation, Psychological; Adolescent; Adolescent Behavior; Adult; Aging; Clonidine; Fluphenazine; F | 1987 |
Treatment of Gilles de la Tourette's syndrome: eight-year, practice-based experience in a predominantly adult population.
Topics: Adolescent; Adult; Age Factors; Child; Clonidine; Female; Haloperidol; Humans; Male; Middle Aged; Pi | 1987 |
Tourette syndrome and drug addiction.
Topics: Clonidine; Humans; Substance-Related Disorders; Tourette Syndrome | 1985 |