clonidine has been researched along with Chronic Lung Injury in 3 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Male Sprague-Dawley rats underwent 6 days of restraint stress after lung contusion/hemorrhagic shock during which the animals received clonidine (75 μg/kg) after the restraint stress." | 7.85 | Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Mohr, AM; Ramos, H, 2017) |
| "Male Sprague-Dawley rats were allocated to naïve control, lung contusion followed by hemorrhagic shock (LCHS), or LCHS plus daily chronic restraint stress (LCHS/CS) ±propranolol, ±clonidine." | 3.91 | The effects of propranolol and clonidine on bone marrow expression of hematopoietic cytokines following trauma and chronic stress. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Millar, JK; Miller, ES; Mohr, AM, 2019) |
| "Clonidine increased VEGF and VEGF-receptor expression, decreased HMGB1 expression, decreased lung inflammation, and improved lung tissue repair." | 3.85 | Clonidine restores vascular endothelial growth factor expression and improves tissue repair following severe trauma. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Millar, JK; Mohr, AM; Plazas, JM; Thomson, AJ; Whitley, EE, 2017) |
| "Male Sprague-Dawley rats underwent 6 days of restraint stress after lung contusion/hemorrhagic shock during which the animals received clonidine (75 μg/kg) after the restraint stress." | 3.85 | Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress. ( Alamo, IG; Efron, PA; Kannan, KB; Loftus, TJ; Mohr, AM; Ramos, H, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loftus, TJ | 3 |
| Thomson, AJ | 1 |
| Kannan, KB | 3 |
| Alamo, IG | 3 |
| Millar, JK | 2 |
| Plazas, JM | 1 |
| Whitley, EE | 1 |
| Efron, PA | 3 |
| Mohr, AM | 3 |
| Miller, ES | 1 |
| Ramos, H | 1 |
3 other studies available for clonidine and Chronic Lung Injury
| Article | Year |
|---|---|
Clonidine restores vascular endothelial growth factor expression and improves tissue repair following severe trauma.
Topics: Animals; Clonidine; HMGB1 Protein; Inflammation; Lung Injury; Propranolol; Pulmonary Edema; Rats; Ra | 2017 |
The effects of propranolol and clonidine on bone marrow expression of hematopoietic cytokines following trauma and chronic stress.
Topics: Anemia; Animals; Biomarkers; Bone Marrow; Chronic Disease; Clonidine; Contusions; Cytokines; Drug Th | 2019 |
Clonidine reduces norepinephrine and improves bone marrow function in a rodent model of lung contusion, hemorrhagic shock, and chronic stress.
Topics: Animals; Bone Marrow; Chronic Disease; Clonidine; Contusions; Disease Models, Animal; Granulocyte Co | 2017 |