clonidine has been researched along with Cerebral Palsy, Athetoid in 19 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare diazepam use, muscle spasm, analgesia, and side effects when clonidine or fentanyl are added to epidural bupivacaine in children with cerebral palsy after multilevel orthopaedic surgery." | 9.22 | Comparison of lumbar epidural bupivacaine with fentanyl or clonidine for postoperative analgesia in children with cerebral palsy after single-event multilevel surgery. ( Chalkiadis, GA; Dowden, SJ; Graham, HK; Low, J; Orsini, F; Penrose, S; Pirpiris, M; Sommerfield, D; Tay, M, 2016) |
| "Cerebral palsy is usually spastic, and baclofen, benzodiazepines and tizanidine are considered as oral treatments." | 9.13 | [Protocol for tizanidine use in infantile cerebral palsy]. ( Arroyo Riaño, O; Benavente Valdepeñas, A; Palazón García, R, 2008) |
| " Following botulinum toxin A treatment, clinical improvement led to the gradual reduction of baclofen or tizanidine dosing to one-third of the former dose." | 5.43 | Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity. ( Aksoy, SN; Dai, AI; Demiryürek, AT, 2016) |
| "Clonidine is a frequently administered alpha2-adrenergic agonist which can decrease heart rate and blood pressure." | 5.34 | Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine. ( Goldfinger, MM; Tripi, PA, 2007) |
| "To compare diazepam use, muscle spasm, analgesia, and side effects when clonidine or fentanyl are added to epidural bupivacaine in children with cerebral palsy after multilevel orthopaedic surgery." | 5.22 | Comparison of lumbar epidural bupivacaine with fentanyl or clonidine for postoperative analgesia in children with cerebral palsy after single-event multilevel surgery. ( Chalkiadis, GA; Dowden, SJ; Graham, HK; Low, J; Orsini, F; Penrose, S; Pirpiris, M; Sommerfield, D; Tay, M, 2016) |
| "Cerebral palsy is usually spastic, and baclofen, benzodiazepines and tizanidine are considered as oral treatments." | 5.13 | [Protocol for tizanidine use in infantile cerebral palsy]. ( Arroyo Riaño, O; Benavente Valdepeñas, A; Palazón García, R, 2008) |
| "For localized/segmental spasticity, botulinum toxin type A is established as an effective treatment to reduce spasticity in the upper and lower extremities." | 2.46 | Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child ( Aisen, M; Ashwal, S; Delgado, MR; Fehlings, DL; Hirtz, D; McLaughlin, J; Morrison, LA; Shrader, MW; Tilton, A; Vargus-Adams, J, 2010) |
| "While in some children, spasticity may adversely impact the motor abilities, in others, it may help maintain posture and ability to ambulate." | 2.43 | Pharmacologic interventions for reducing spasticity in cerebral palsy. ( Patel, DR; Soyode, O, 2005) |
| "Isolated dystonia or spasticity was infrequently seen, with a mixed picture of dystonia and spasticity ± choreoathetosis identified in 194/275 (70." | 1.51 | Pharmacological management of abnormal tone and movement in cerebral palsy. ( Amin, S; Basu, A; Cadwgan, J; Crowe, B; DeAlwis, Y; Devlin, A; Kumar, R; Lodh, R; Lumsden, DE; Lundy, CT; Mordekar, SR; Smith, M, 2019) |
| " Following botulinum toxin A treatment, clinical improvement led to the gradual reduction of baclofen or tizanidine dosing to one-third of the former dose." | 1.43 | Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity. ( Aksoy, SN; Dai, AI; Demiryürek, AT, 2016) |
| "Clonidine is a frequently administered alpha2-adrenergic agonist which can decrease heart rate and blood pressure." | 1.34 | Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine. ( Goldfinger, MM; Tripi, PA, 2007) |
| " Secondary objectives included determining correlations between dosage and age, injury type, location of spasticity, comorbid seizures, or concomitant antispasticity medications." | 1.33 | Oral baclofen and clonidine for treatment of spasticity in children. ( Haase, M; Habersang, R; Lubsch, L; Luedtke, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 6 (31.58) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Bohn, E | 1 |
| Goren, K | 1 |
| Switzer, L | 1 |
| Falck-Ytter, Y | 1 |
| Fehlings, D | 1 |
| Arshad, MF | 1 |
| Ahmad, E | 1 |
| Biddanda, AN | 1 |
| Sharif, M | 1 |
| Lumsden, DE | 1 |
| Crowe, B | 1 |
| Basu, A | 1 |
| Amin, S | 1 |
| Devlin, A | 1 |
| DeAlwis, Y | 1 |
| Kumar, R | 1 |
| Lodh, R | 1 |
| Lundy, CT | 1 |
| Mordekar, SR | 1 |
| Smith, M | 1 |
| Cadwgan, J | 1 |
| Dai, AI | 2 |
| Aksoy, SN | 1 |
| Demiryürek, AT | 1 |
| Chalkiadis, GA | 2 |
| Sommerfield, D | 1 |
| Low, J | 1 |
| Orsini, F | 1 |
| Dowden, SJ | 1 |
| Tay, M | 1 |
| Penrose, S | 1 |
| Pirpiris, M | 1 |
| Graham, HK | 1 |
| Wasay, M | 1 |
| Awan, S | 1 |
| Delgado, MR | 1 |
| Hirtz, D | 1 |
| Aisen, M | 1 |
| Ashwal, S | 1 |
| Fehlings, DL | 1 |
| McLaughlin, J | 1 |
| Morrison, LA | 1 |
| Shrader, MW | 1 |
| Tilton, A | 1 |
| Vargus-Adams, J | 1 |
| Chung, CY | 1 |
| Chen, CL | 1 |
| Wong, AM | 1 |
| Patel, DR | 1 |
| Soyode, O | 1 |
| Lubsch, L | 1 |
| Habersang, R | 1 |
| Haase, M | 1 |
| Luedtke, S | 1 |
| Goldfinger, MM | 1 |
| Tripi, PA | 1 |
| Skinner, AV | 1 |
| Feron, FJ | 1 |
| Hendriksen, JG | 1 |
| Nicolai, J | 1 |
| Vles, JS | 1 |
| Palazón García, R | 1 |
| Benavente Valdepeñas, A | 1 |
| Arroyo Riaño, O | 1 |
| Knutsson, E | 1 |
| Shumilina, AP | 1 |
| Guzeva, VI | 1 |
| Skoromets, AA | 1 |
| Maksimov, OG | 1 |
| Secheĭko, MV | 1 |
| Andriĭchuk, EL | 1 |
| Brin, IL | 1 |
| Kurenkov, AL | 1 |
| Gotlib, VIa | 1 |
| Autti-Rämö, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Radial Extracorporeal Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy[NCT05702606] | 73 participants (Actual) | Interventional | 2021-06-10 | Completed | |||
| Sensory-Motor Rehabilitation Post Stroke[NCT02369770] | 140 participants (Anticipated) | Interventional | 2019-04-26 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for clonidine and Cerebral Palsy, Athetoid
| Article | Year |
|---|---|
Pharmacological and neurosurgical interventions for individuals with cerebral palsy and dystonia: a systematic review update and meta-analysis.
Topics: Baclofen; Botulinum Toxins; Cerebral Palsy; Clonidine; Deep Brain Stimulation; Dystonia; Humans; Inj | 2021 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
Practice parameter: pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child
Topics: Adolescent; Botulinum Toxins, Type A; Cerebral Palsy; Child; Clonidine; Diazepam; Humans; Muscle Rel | 2010 |
Pharmacotherapy of spasticity in children with cerebral palsy.
Topics: Baclofen; Benzodiazepines; Cerebral Palsy; Child; Clonidine; Dantrolene; Humans; Muscle Spasticity; | 2011 |
Pharmacologic interventions for reducing spasticity in cerebral palsy.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Age Factors; Anti-Infective Agents, Local; Baclofen | 2005 |
[Treatment of spasticity].
Topics: Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Clonidine; Humans; Injections, Spinal; Muscle Re | 1999 |
5 trials available for clonidine and Cerebral Palsy, Athetoid
| Article | Year |
|---|---|
Comparison of lumbar epidural bupivacaine with fentanyl or clonidine for postoperative analgesia in children with cerebral palsy after single-event multilevel surgery.
Topics: Analgesics; Bupivacaine; Cerebral Palsy; Child; Clonidine; Drug Therapy, Combination; Female; Fentan | 2016 |
Botulinum toxin type A with oral baclofen versus oral tizanidine: a nonrandomized pilot comparison in patients with cerebral palsy and spastic equinus foot deformity.
Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Chi-Square Dis | 2008 |
[Protocol for tizanidine use in infantile cerebral palsy].
Topics: Cerebral Palsy; Child; Child, Preschool; Clonidine; Drug Administration Schedule; Female; Humans; In | 2008 |
[The use of sirdalud in the treatment of spasticity in infantile cerebral palsy].
Topics: Adolescent; Anticonvulsants; Cerebral Palsy; Child; Child, Preschool; Clonidine; Dose-Response Relat | 1999 |
[The use of sirdalud in cerebral palsy in children].
Topics: Adolescent; Cerebral Palsy; Child; Clonidine; Dose-Response Relationship, Drug; Electromyography; Fe | 1999 |
9 other studies available for clonidine and Cerebral Palsy, Athetoid
| Article | Year |
|---|---|
Status dystonicus: a diagnosis delayed.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Adult; Cerebral Palsy; Clonidine; | 2018 |
Pharmacological management of abnormal tone and movement in cerebral palsy.
Topics: Adolescent; Baclofen; Botulinum Toxins; Cerebral Palsy; Child; Child Health Services; Child, Prescho | 2019 |
Comparison of Efficacy and Side Effects of Oral Baclofen Versus Tizanidine Therapy with Adjuvant Botulinum Toxin Type A in Children With Cerebral Palsy and Spastic Equinus Foot Deformity.
Topics: Administration, Oral; Adolescent; Baclofen; Botulinum Toxins, Type A; Cerebral Palsy; Child; Child, | 2016 |
Oral baclofen and clonidine for treatment of spasticity in children.
Topics: Administration, Oral; Adolescent; Adrenergic alpha-Agonists; Adult; Age Factors; Baclofen; Brain Inj | 2006 |
Cardiac arrest in a child with cerebral palsy undergoing sevoflurane induction of anesthesia after preoperative clonidine.
Topics: Adrenergic alpha-Agonists; Anesthesia, General; Anesthetics, Inhalation; Cerebral Palsy; Child, Pres | 2007 |
Clinically unrecognized intravascular placement of epidural catheter in a child--an argument for the use of radio-opaque contrast?
Topics: Adrenergic Agonists; Analgesia, Epidural; Analgesics; Anesthetics, Local; Blood Pressure; Bupivacain | 2007 |
New-onset seizures: a possible association with clonidine?
Topics: Adrenergic alpha-Agonists; Anticonvulsants; Attention Deficit Disorder with Hyperactivity; Cerebral | 2008 |
Analysis of gait and isokinetic movements for evaluation of antispastic drugs or physical therapies.
Topics: Cerebral Palsy; Clonidine; Electromyography; Gait; Humans; Motor Neurons; Muscle Contraction; Muscle | 1983 |
[Sirdalud in the practice of the pediatric neurologist].
Topics: Adolescent; Cerebral Palsy; Child; Clonidine; Drug Evaluation; Humans; Muscle Relaxants, Central; Mu | 1997 |