clonidine has been researched along with Central Hypothyroidism in 19 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Adrenoceptor-mediated responses of the cardiovascular system during propylthiouracil-induced hypothyroidism were investigated." | 7.66 | Changes of adrenoceptor-mediated responses in the pithed rat during propylthiouracil-induced hypothyroidism. ( Borowski, E; Gross, G; Schümann, HJ, 1979) |
| "Clonidine-induced hypoactivity was studied in rats made neonatally hypo- and hyperthyroid (PTU or T4 administered between 1-27 days postnatally) as an indication of central presynaptic alpha 2-adrenoceptor function." | 3.67 | Effects of thyroid status on clonidine-induced hypoactivity responses in the developing rat. ( Atterwill, CK; Heal, DJ; Smith, SD, 1984) |
| " Repeated triiodothyronine (T3) administration to rats (100 micrograms/kg X 14 days: hyperthyroid) caused an 18% increase in striatal beta-adrenoceptors as shown by [3H]-dihydroalprenolol binding with no change in membranes from cerebral cortex or hypothalamus." | 3.67 | Effects of thyroid status on presynaptic alpha 2-adrenoceptor function and beta-adrenoceptor binding in the rat brain. ( Atkinson, DJ; Atterwill, CK; Bunn, SJ; Heal, DJ; Smith, SL, 1984) |
| " Four groups of rats: hypothyroid, hyperthyroid, thyroxine (0." | 3.67 | The effect of hyperthyroidism and hypothyroidism on alpha 1- and alpha 2-adrenergic responsiveness in rat aortic smooth muscle. ( Cheema, IR; Peoples, B; Rahmani, MA; Riley, SR; Sen, S, 1987) |
| " In order to find out whether similar changes exist in the central nervous system, we investigated adrenoceptor-mediated responses in the rat brain cortex during propylthiouracil-induced hypothyroidism." | 3.66 | Effects of thyroid hormone deficiency on pre- and postsynaptic noradrenergic mechanisms in the rat cerebral cortex. ( Brodde, OE; Gross, G; Schümann, HJ, 1980) |
| "Adrenoceptor-mediated responses of the cardiovascular system during propylthiouracil-induced hypothyroidism were investigated." | 3.66 | Changes of adrenoceptor-mediated responses in the pithed rat during propylthiouracil-induced hypothyroidism. ( Borowski, E; Gross, G; Schümann, HJ, 1979) |
| "Hypocalcemia was detected in five of the 30 thalassemic patients: hypoparathyroidism was diagnosed in two of the five and rickets in the other three." | 2.69 | Bone mineral density in prepubertal children with beta-thalassemia: correlation with growth and hormonal data. ( Abdel Fattah, M; Ansari, BM; El Banna, N; ElZalabani, MM; Soliman, AT, 1998) |
| "Clonidine did not cause any inotropic change in the euthyroid rat atrium." | 1.27 | Changes in the effects of clonidine on left atrium and hindlimb vasculature of rats in various thyroid states. A study of the responsiveness of alpha 2-adrenoceptors in the cardiovascular system. ( Nakashima, M; Oguro, K; Ohguchi, S; Sotobata, I, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ghannoum, JE | 1 |
| Odingo, NA | 1 |
| Provost, N | 1 |
| Ohguchi, S | 2 |
| Sotobata, I | 1 |
| Oguro, K | 2 |
| Nakashima, M | 2 |
| Heal, DJ | 2 |
| Smith, SD | 1 |
| Atterwill, CK | 2 |
| Gross, G | 3 |
| Schümann, HJ | 3 |
| Brodde, OE | 1 |
| Bunn, SJ | 1 |
| Atkinson, DJ | 1 |
| Smith, SL | 1 |
| Molinero, P | 1 |
| Osuna, C | 1 |
| Guerrero, JM | 1 |
| Ning, C | 1 |
| Wei, H | 1 |
| Shu, D | 1 |
| Hu, XF | 1 |
| Tao, DD | 1 |
| Lin, HH | 1 |
| Wang, S | 1 |
| Wang, MT | 1 |
| Del Rio, G | 1 |
| Zizzo, G | 1 |
| Marrama, P | 1 |
| Venneri, MG | 1 |
| Della Casa, L | 1 |
| Velardo, A | 1 |
| Soliman, AT | 1 |
| El Banna, N | 1 |
| Abdel Fattah, M | 1 |
| ElZalabani, MM | 1 |
| Ansari, BM | 1 |
| Wajnrajch, MP | 1 |
| Gertner, JM | 1 |
| Huma, Z | 1 |
| Popovic, J | 1 |
| Lin, K | 1 |
| Verlander, PC | 1 |
| Batish, SD | 1 |
| Giampietro, PF | 1 |
| Davis, JG | 1 |
| New, MI | 1 |
| Auerbach, AD | 1 |
| Männistö, PT | 1 |
| Ranta, T | 1 |
| Borowski, E | 1 |
| Nomura, H | 1 |
| Izuhara, K | 1 |
| Nomura, T | 1 |
| Kodama, M | 1 |
| Sugiura, N | 1 |
| Tachibana, M | 1 |
| Hagino, Y | 1 |
| Rahmani, MA | 1 |
| Cheema, IR | 1 |
| Sen, S | 1 |
| Peoples, B | 1 |
| Riley, SR | 1 |
| García-Sáinz, JA | 1 |
| Contreras-Rodríguez, JL | 1 |
| De Gennaro, V | 1 |
| Cella, SG | 1 |
| Bassetti, M | 1 |
| Rizzi, R | 1 |
| Cocchi, D | 1 |
| Muller, EE | 1 |
| Ho, KY | 1 |
| Evans, WS | 1 |
| Thorner, MO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Denosumab Versus Zoledronic Acid for Patients With Beta-Thalassemia Major-Induced Osteoporosis[NCT03040765] | Phase 3 | 17 participants (Actual) | Interventional | 2018-05-14 | Terminated (stopped due to failed to recruit eligible subjects) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for clonidine and Central Hypothyroidism
| Article | Year |
|---|---|
Disorders of prolactin and growth hormone secretion.
Topics: Acromegaly; Arginine; Clonidine; Dwarfism; Female; Glucose Tolerance Test; Growth Hormone; Growth Ho | 1985 |
1 trial available for clonidine and Central Hypothyroidism
| Article | Year |
|---|---|
Bone mineral density in prepubertal children with beta-thalassemia: correlation with growth and hormonal data.
Topics: Absorptiometry, Photon; Adolescent; Adrenocorticotropic Hormone; Age Factors; Alkaline Phosphatase; | 1998 |
17 other studies available for clonidine and Central Hypothyroidism
| Article | Year |
|---|---|
Clinico-pathologic conference: case 6.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Aspirin; Carcinoma, Squamous Cell; | 2009 |
Changes in the effects of clonidine on left atrium and hindlimb vasculature of rats in various thyroid states. A study of the responsiveness of alpha 2-adrenoceptors in the cardiovascular system.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Heart Atria; Hindlimb; Hypothyroidism; In Vitr | 1984 |
Effects of thyroid status on clonidine-induced hypoactivity responses in the developing rat.
Topics: Animals; Animals, Newborn; Clonidine; Female; Hyperthyroidism; Hypothyroidism; Male; Motor Activity; | 1984 |
Reduced number of alpha2-adrenoceptors in cortical brain membranes of hypothyroid rats.
Topics: Animals; Brain; Clonidine; Hypothyroidism; Kinetics; Male; Membranes; Propylthiouracil; Rats; Rats, | 1981 |
Effects of thyroid hormone deficiency on pre- and postsynaptic noradrenergic mechanisms in the rat cerebral cortex.
Topics: Animals; Cerebral Cortex; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Hypothyroidism; I | 1980 |
Effects of thyroid status on presynaptic alpha 2-adrenoceptor function and beta-adrenoceptor binding in the rat brain.
Topics: Animals; Brain; Clonidine; Dihydroalprenolol; Hyperthyroidism; Hypothyroidism; Rats; Receptors, Adre | 1984 |
Induction of opposite response of hindlimb vasculature to adrenergic agents in hypothyroid rats.
Topics: Acetylcholine; Animals; Blood Pressure; Clonidine; Heart Rate; Hindlimb; Hypothyroidism; In Vitro Te | 1984 |
Type II thyroxine 5'-deiodinase in the rat thymus.
Topics: Animals; Cell Membrane; Clonidine; Female; Hypothyroidism; Iodide Peroxidase; Isoproterenol; Male; M | 1995 |
Clinical significance of multiple hypothalamic-pituitary functions assessment in patients with Turner's syndrome.
Topics: Adolescent; Adult; Child; Child, Preschool; Clonidine; Female; Humans; Hypothalamo-Hypophyseal Syste | 1994 |
Alpha 2-adrenergic activity is normal in patients with thyroid disease.
Topics: Adult; Blood Pressure; Catecholamines; Clonidine; Epinephrine; Female; Humans; Hyperthyroidism; Hypo | 1994 |
Evaluation of growth and hormonal status in patients referred to the International Fanconi Anemia Registry.
Topics: Adolescent; Adult; Anthropometry; Body Height; Child; Child, Preschool; Clonidine; Diabetes Mellitus | 2001 |
Neurotransmitter control of thyrotrophin secretion in hypothyroid rats.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonidine; Ditiocarb; Fenclonine; Hypothyr | 1978 |
Changes of adrenoceptor-mediated responses in the pithed rat during propylthiouracil-induced hypothyroidism.
Topics: Animals; Atropine; Blood Pressure; Bupranolol; Clonidine; Disease Models, Animal; Electric Stimulati | 1979 |
The interaction of alpha- and beta-adrenergic agonists on amylase release from parotid glands of euthyroid and hypothyroid rats.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Amylases; Animals; Bucladesine; Calcium; Clonid | 1986 |
The effect of hyperthyroidism and hypothyroidism on alpha 1- and alpha 2-adrenergic responsiveness in rat aortic smooth muscle.
Topics: Animals; Aorta; Clonidine; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Male; Muscle Contra | 1987 |
Possible existence of two mechanisms involved in alpha 1-adrenergic action: effect of Sgd 101/75.
Topics: Adrenalectomy; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Calcium; Clonidine; | 1986 |
Impaired growth hormone secretion in neonatal hypothyroid rats: hypothalamic versus pituitary component.
Topics: Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus; Clonidine; Growth Hormone; Growth Hormon | 1988 |