Page last updated: 2024-10-25

clonidine and Cardiac Diseases

clonidine has been researched along with Cardiac Diseases in 17 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Research Excerpts

ExcerptRelevanceReference
"Cardiac arrhythmias and cardiac arrest were induced in pentobarbitone anaesthetised cats by slow intravenous infusion of ouabain."3.68Protective effect of clonidine against the cardiotoxic effects of ouabain in cat. ( Stephen, PM; Thomas, GP, 1990)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19909 (52.94)18.7374
1990's2 (11.76)18.2507
2000's4 (23.53)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duncan, D1
Sankar, A1
Beattie, WS3
Wijeysundera, DN3
Choi, PT1
Badner, NH1
Brasher, PM1
Dresser, GK1
Delgado, DH1
Bender, JS1
Roos, M1
Aantaa, R1
Jalonen, J1
Margolis, KL1
Piller, LB1
Ford, CE1
Henriquez, MA1
Cushman, WC1
Einhorn, PT1
Colon, PJ1
Vidt, DG1
Christian, R1
Wong, ND1
Wright, JT1
Goff, DC1
Fleming, SE1
Horvath, JS1
Korda, A1
Casiglia, E1
Spolaore, P1
Mazza, A1
Ginocchio, G1
Colangeli, G1
Onesto, C1
Di Menza, G1
Pegoraro, L1
Ambrosio, GB1
Enenkel, W1
Zweifler, AJ1
Esler, M1
Thomas, GP1
Stephen, PM1
Schalekamp, MA1
Man in't Veld, AJ1
Auffray, JP1
Eon, B1
Ouerghemmi, D1
Aknin, P1
Blin, D1
Knudsen, K1
Ricksten, SE1
Heath, A1
Magioncalda, A1
Setti, S1
Cecchi, A1
Tampoia, V1
Bennio, M1
Visani, L1
Bauer, GE1
Persico, L1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Intraoperative Goal-directed Blood Pressure Management and Dexmedetomidine on Outcomes of High-risk Patients After Major Abdominal Surgeries: a 2×2 Factorial Randomized Controlled Trial[NCT03933306]Phase 4496 participants (Actual)Interventional2019-05-20Active, not recruiting
The EPIC (Evaluating Perioperative Ischemia Reduction by Clonidine) Study: A Randomized, Double-blinded Trial of Clonidine for Reducing Cardiac Morbidity and Mortality Following Non-cardiac Surgery.[NCT00335582]Phase 4165 participants (Anticipated)Interventional2006-06-30Active, not recruiting
[NCT00000542]Phase 30 participants Interventional1993-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for clonidine and Cardiac Diseases

ArticleYear
Alpha-2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery.
    The Cochrane database of systematic reviews, 2018, 03-06, Volume: 3

    Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Imidazoles; Intraoper

2018
Alpha-2 adrenergic agonists for the prevention of cardiac complications among patients undergoing surgery.
    The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4

    Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Imidazoles; Intraoper

2009
Perioperative use of alpha2-adrenoceptor agonists and the cardiac patient.
    European journal of anaesthesiology, 2006, Volume: 23, Issue:5

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Cardiovascular Physiological Phenom

2006
[Cardiac therapy in the old patient].
    Wiener medizinische Wochenschrift (1946), 1979, Oct-10, Volume: 129, Issue:18

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycos

1979
Mono-aminergic receptors and blood pressure.
    The Netherlands journal of medicine, 1985, Volume: 28, Issue:2

    Topics: Adrenergic beta-Agonists; Blood Pressure; Catechol O-Methyltransferase; Cell Membrane; Clonidine; Do

1985

Trials

3 trials available for clonidine and Cardiac Diseases

ArticleYear
A randomized feasibility trial of clonidine to reduce perioperative cardiac risk in patients on chronic beta-blockade: the EPIC study.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2014, Volume: 61, Issue:11

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Canada; Clonidine; Double-Blind Method; Dru

2014
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthal

2007
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
    Japanese heart journal, 1994, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Hea

1994

Other Studies

9 other studies available for clonidine and Cardiac Diseases

ArticleYear
[With diabetes into the mountains. The metabolism derails faster].
    MMW Fortschritte der Medizin, 2005, Apr-07, Volume: 147, Issue:14

    Topics: Acclimatization; Antihypertensive Agents; Blood Glucose; Clonidine; Diabetes Mellitus; Heart Disease

2005
Errors in the measurement of blood pressure.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1983, Volume: 23, Issue:3

    Topics: Blood Pressure Determination; Cardiac Catheterization; Clonidine; False Negative Reactions; Female;

1983
Factors influencing the choice of antihypertensive agents.
    Postgraduate medicine, 1976, Volume: 60, Issue:7

    Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications;

1976
Protective effect of clonidine against the cardiotoxic effects of ouabain in cat.
    Indian journal of physiology and pharmacology, 1990, Volume: 34, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Clonidine; Female; Heart Arrest; Heart Diseases

1990
[Hemodynamic effects of alinidine in the early postoperative phase of cardiac surgery].
    Presse medicale (Paris, France : 1983), 1988, Oct-29, Volume: 17, Issue:38

    Topics: Adult; Aged; Cardiovascular Agents; Clonidine; Female; Heart Diseases; Hemodynamics; Humans; Male; M

1988
Clonidine interaction in amitriptyline poisoning.
    Journal of toxicology. Clinical toxicology, 1988, Volume: 26, Issue:3-4

    Topics: Amitriptyline; Animals; Blood Pressure; Clonidine; Heart Conduction System; Heart Diseases; Heart Ra

1988
[Use of clonidine in the prevention of intraoperative hypertensive crisis. Study on cardiopathic and hypertensive patients subjected to cataract surgery under local anesthesia].
    La Clinica terapeutica, 1986, Apr-30, Volume: 117, Issue:2

    Topics: Aged; Anesthesia, Local; Cataract Extraction; Clonidine; Female; Heart Diseases; Humans; Hypertensio

1986
Treatment of hypertension in the elderly.
    Drugs, 1974, Volume: 7, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Clonidine; Di

1974
[Pathogenesis and therapy of acute pulmonary edema].
    Il Policlinico. Sezione pratica, 1972, Jan-01, Volume: 79, Issue:1

    Topics: Acute Disease; Brain Diseases; Cardiac Glycosides; Clonidine; Diuretics; Gas Poisoning; Heart Defect

1972