clonidine has been researched along with Cardiac Diseases in 17 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiac arrhythmias and cardiac arrest were induced in pentobarbitone anaesthetised cats by slow intravenous infusion of ouabain." | 3.68 | Protective effect of clonidine against the cardiotoxic effects of ouabain in cat. ( Stephen, PM; Thomas, GP, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Duncan, D | 1 |
| Sankar, A | 1 |
| Beattie, WS | 3 |
| Wijeysundera, DN | 3 |
| Choi, PT | 1 |
| Badner, NH | 1 |
| Brasher, PM | 1 |
| Dresser, GK | 1 |
| Delgado, DH | 1 |
| Bender, JS | 1 |
| Roos, M | 1 |
| Aantaa, R | 1 |
| Jalonen, J | 1 |
| Margolis, KL | 1 |
| Piller, LB | 1 |
| Ford, CE | 1 |
| Henriquez, MA | 1 |
| Cushman, WC | 1 |
| Einhorn, PT | 1 |
| Colon, PJ | 1 |
| Vidt, DG | 1 |
| Christian, R | 1 |
| Wong, ND | 1 |
| Wright, JT | 1 |
| Goff, DC | 1 |
| Fleming, SE | 1 |
| Horvath, JS | 1 |
| Korda, A | 1 |
| Casiglia, E | 1 |
| Spolaore, P | 1 |
| Mazza, A | 1 |
| Ginocchio, G | 1 |
| Colangeli, G | 1 |
| Onesto, C | 1 |
| Di Menza, G | 1 |
| Pegoraro, L | 1 |
| Ambrosio, GB | 1 |
| Enenkel, W | 1 |
| Zweifler, AJ | 1 |
| Esler, M | 1 |
| Thomas, GP | 1 |
| Stephen, PM | 1 |
| Schalekamp, MA | 1 |
| Man in't Veld, AJ | 1 |
| Auffray, JP | 1 |
| Eon, B | 1 |
| Ouerghemmi, D | 1 |
| Aknin, P | 1 |
| Blin, D | 1 |
| Knudsen, K | 1 |
| Ricksten, SE | 1 |
| Heath, A | 1 |
| Magioncalda, A | 1 |
| Setti, S | 1 |
| Cecchi, A | 1 |
| Tampoia, V | 1 |
| Bennio, M | 1 |
| Visani, L | 1 |
| Bauer, GE | 1 |
| Persico, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Intraoperative Goal-directed Blood Pressure Management and Dexmedetomidine on Outcomes of High-risk Patients After Major Abdominal Surgeries: a 2×2 Factorial Randomized Controlled Trial[NCT03933306] | Phase 4 | 496 participants (Actual) | Interventional | 2019-05-20 | Active, not recruiting | ||
| The EPIC (Evaluating Perioperative Ischemia Reduction by Clonidine) Study: A Randomized, Double-blinded Trial of Clonidine for Reducing Cardiac Morbidity and Mortality Following Non-cardiac Surgery.[NCT00335582] | Phase 4 | 165 participants (Anticipated) | Interventional | 2006-06-30 | Active, not recruiting | ||
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for clonidine and Cardiac Diseases
| Article | Year |
|---|---|
Alpha-2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery.
Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Imidazoles; Intraoper | 2018 |
Alpha-2 adrenergic agonists for the prevention of cardiac complications among patients undergoing surgery.
Topics: Adrenergic alpha-Agonists; Clonidine; Dexmedetomidine; Heart Diseases; Humans; Imidazoles; Intraoper | 2009 |
Perioperative use of alpha2-adrenoceptor agonists and the cardiac patient.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Cardiovascular Physiological Phenom | 2006 |
[Cardiac therapy in the old patient].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Body Water; Calcium; Clonidine; Digitalis Glycos | 1979 |
Mono-aminergic receptors and blood pressure.
Topics: Adrenergic beta-Agonists; Blood Pressure; Catechol O-Methyltransferase; Cell Membrane; Clonidine; Do | 1985 |
3 trials available for clonidine and Cardiac Diseases
| Article | Year |
|---|---|
A randomized feasibility trial of clonidine to reduce perioperative cardiac risk in patients on chronic beta-blockade: the EPIC study.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Canada; Clonidine; Double-Blind Method; Dru | 2014 |
Blood pressure control in Hispanics in the antihypertensive and lipid-lowering treatment to prevent heart attack trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atenolol; Black People; Blood Pressure; Canada; Chlorthal | 2007 |
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Hea | 1994 |
9 other studies available for clonidine and Cardiac Diseases
| Article | Year |
|---|---|
[With diabetes into the mountains. The metabolism derails faster].
Topics: Acclimatization; Antihypertensive Agents; Blood Glucose; Clonidine; Diabetes Mellitus; Heart Disease | 2005 |
Errors in the measurement of blood pressure.
Topics: Blood Pressure Determination; Cardiac Catheterization; Clonidine; False Negative Reactions; Female; | 1983 |
Factors influencing the choice of antihypertensive agents.
Topics: Age Factors; Aldosterone; Cerebrovascular Disorders; Clonidine; Depression; Diabetes Complications; | 1976 |
Protective effect of clonidine against the cardiotoxic effects of ouabain in cat.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Clonidine; Female; Heart Arrest; Heart Diseases | 1990 |
[Hemodynamic effects of alinidine in the early postoperative phase of cardiac surgery].
Topics: Adult; Aged; Cardiovascular Agents; Clonidine; Female; Heart Diseases; Hemodynamics; Humans; Male; M | 1988 |
Clonidine interaction in amitriptyline poisoning.
Topics: Amitriptyline; Animals; Blood Pressure; Clonidine; Heart Conduction System; Heart Diseases; Heart Ra | 1988 |
[Use of clonidine in the prevention of intraoperative hypertensive crisis. Study on cardiopathic and hypertensive patients subjected to cataract surgery under local anesthesia].
Topics: Aged; Anesthesia, Local; Cataract Extraction; Clonidine; Female; Heart Diseases; Humans; Hypertensio | 1986 |
Treatment of hypertension in the elderly.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cerebrovascular Disorders; Clonidine; Di | 1974 |
[Pathogenesis and therapy of acute pulmonary edema].
Topics: Acute Disease; Brain Diseases; Cardiac Glycosides; Clonidine; Diuretics; Gas Poisoning; Heart Defect | 1972 |