clonidine has been researched along with Carcinoma in 4 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Carcinoma: A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was aimed to prepare nanoparticles of tizanidine hydrochloride using biodegradable polymers and loading them on orodispersible films to obtain a sustained release dissolution profile with improved permeability and further study the cytotoxicity on A549 lung carcinoma cells, MCF7 breast cancer cells, and HOP 92 non-small lung adenocarcinoma cells." | 4.12 | Development of Biocompatible Nanoparticles of Tizanidine Hydrochloride in Orodispersible Films: ( Dutt, R; Kaushik, D; Mittal, V; Pandey, P; Rahman, MH; Singh, S; Sinha, S; Thapa, S; Verma, R, 2022) |
| "alpha 2-adrenergic receptor-mediated signal transduction in rat adrenocortical carcinoma cells occurs through the opposing regulation of two second messengers, cyclic GMP and cyclic AMP, in which guanylate cyclase is coupled positively and adenylate cyclase negatively to the receptor signal." | 3.67 | Inhibition of alpha 2-adrenergic receptor-mediated cyclic GMP formation by a phorbol ester, a protein kinase C activator. ( Jaiswal, RK; Sharma, RK, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sinha, S | 1 |
| Thapa, S | 1 |
| Singh, S | 1 |
| Dutt, R | 1 |
| Verma, R | 1 |
| Pandey, P | 1 |
| Mittal, V | 1 |
| Rahman, MH | 1 |
| Kaushik, D | 1 |
| Coombs, DW | 1 |
| Saunders, RL | 1 |
| Fratkin, JD | 1 |
| Jensen, LE | 1 |
| Murphy, CA | 1 |
| Jaiswal, RK | 1 |
| Sharma, RK | 1 |
| Krames, ES | 1 |
| Wilkie, DJ | 1 |
| Gershow, J | 1 |
4 other studies available for clonidine and Carcinoma
| Article | Year |
|---|---|
Development of Biocompatible Nanoparticles of Tizanidine Hydrochloride in Orodispersible Films:
Topics: Animals; Biological Availability; Carcinoma; Clonidine; Drug Delivery Systems; Nanoparticles; Polyme | 2022 |
Continuous intrathecal hydromorphone and clonidine for intractable cancer pain.
Topics: Carcinoma; Clonidine; Female; Humans; Hydromorphone; Injections, Spinal; Middle Aged; Pain, Intracta | 1986 |
Inhibition of alpha 2-adrenergic receptor-mediated cyclic GMP formation by a phorbol ester, a protein kinase C activator.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Cortex Neoplasms; Animals; Carcinoma; Clonidi | 1988 |
Intrathecal D-Ala2-D-Leu5-enkephalin (DADL) restores analgesia in a patient analgetically tolerant to intrathecal morphine sulfate.
Topics: Aged; Carcinoma; Clonidine; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Huma | 1986 |