clonidine has been researched along with Cannabis Abuse in 4 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lofexidine was sedating, worsened abstinence-related anorexia, and did not robustly attenuate withdrawal, but improved sleep and decreased marijuana relapse." | 2.73 | Effects of THC and lofexidine in a human laboratory model of marijuana withdrawal and relapse. ( Comer, SD; Foltin, RW; Haney, M; Hart, CL; Reed, SC; Vosburg, SK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brezing, CA | 1 |
| Choi, CJ | 1 |
| Pavlicova, M | 2 |
| Brooks, D | 2 |
| Mahony, AL | 1 |
| Mariani, JJ | 2 |
| Levin, FR | 2 |
| Glass, A | 1 |
| Mahony, A | 1 |
| Nunes, EV | 1 |
| Bisaga, A | 1 |
| Dakwar, E | 1 |
| Carpenter, KM | 1 |
| Sullivan, MA | 1 |
| Choi, JC | 1 |
| Haney, M | 1 |
| Hart, CL | 1 |
| Vosburg, SK | 1 |
| Comer, SD | 1 |
| Reed, SC | 1 |
| Foltin, RW | 1 |
| Cone, EJ | 1 |
| Welch, P | 1 |
| Lange, WR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Double-Blind, Placebo-Controlled Study of Lofexidine and Dronabinol for the Treatment of Marijuana Dependence[NCT01020019] | Phase 2/Phase 3 | 156 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01020019)
Timeframe: reported daily for 12 weeks/ or study participation
| Intervention | participants (Number) |
|---|---|
| Placebo | 18 |
| Lofexidine and Dronabinol | 17 |
3 trials available for clonidine and Cannabis Abuse
| Article | Year |
|---|---|
Abstinence and reduced frequency of use are associated with improvements in quality of life among treatment-seekers with cannabis use disorder.
Topics: Adult; Clonidine; Double-Blind Method; Dronabinol; Female; Humans; Male; Marijuana Abuse; Marijuana | 2018 |
Dronabinol and lofexidine for cannabis use disorder: A randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adult; Cannabinoid Receptor Agonists; Clonidine; Craving; Double-Blind Method; Dronabino | 2016 |
Effects of THC and lofexidine in a human laboratory model of marijuana withdrawal and relapse.
Topics: Adrenergic alpha-Agonists; Adult; Affect; Appetite; Attention; Cannabinoids; Clonidine; Double-Blind | 2008 |
1 other study available for clonidine and Cannabis Abuse
| Article | Year |
|---|---|
Clonidine partially blocks the physiologic effects but not the subjective effects produced by smoking marijuana in male human subjects.
Topics: Adrenocorticotropic Hormone; Blood Pressure; Clonidine; Drug Evaluation; Heart Rate; Humans; Male; M | 1988 |