Page last updated: 2024-10-25

clonidine and Burns

clonidine has been researched along with Burns in 14 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Burns: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Research Excerpts

ExcerptRelevanceReference
" Midazolam, S+ ketamine, placebo, or clonidine was used for the anesthesia."9.19Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT. ( Pretto, G; Silva, E; Westphal, GA, 2014)
"Clonidine 1 mg/kg ip given before thermal injury significantly inhibited the edema formation in mice and rats during the early stage of burn."7.67[Inhibitory effects of clonidine on edema formation after thermal injury in mice and rats]. ( Jiang, DJ; Tao, JY; Xu, SY, 1989)
" Midazolam, S+ ketamine, placebo, or clonidine was used for the anesthesia."5.19Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT. ( Pretto, G; Silva, E; Westphal, GA, 2014)
"Clonidine 1 mg/kg ip given before thermal injury significantly inhibited the edema formation in mice and rats during the early stage of burn."3.67[Inhibitory effects of clonidine on edema formation after thermal injury in mice and rats]. ( Jiang, DJ; Tao, JY; Xu, SY, 1989)
"Whether the additional PTSD and functional neurologic deficits were due to a direct effect of the lightning strike on the central nervous system or a secondary response is open to speculation."1.39Central hyperadrenergic state after lightning strike. ( Ahlskog, JE; Craft, JM; Gelfman, R; Kantor, B; Low, PA; Parsaik, AK; Seime, RJ; Sheldon, SH; Singer, W; Staab, JP, 2013)
"Terazosin was administered before the burn injury at one site, and after the burn injury at the other site."1.35alpha(1)-Adrenoceptors augment thermal hyperalgesia in mildly burnt skin. ( Drummond, PD, 2009)
"Clonidine has both analgesic and sedative actions, and it has been used in a variety of settings as a sedative, or both."1.30Oral clonidine for sedation and analgesia in a burn patient. ( Asada, A; Kariya, N; Nishi, S; Shindoh, M; Yukioka, H, 1998)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's5 (35.71)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Gus, EI1
Shahrokhi, S1
Jeschke, MG1
Parsaik, AK1
Ahlskog, JE1
Singer, W1
Gelfman, R1
Sheldon, SH1
Seime, RJ1
Craft, JM1
Staab, JP1
Kantor, B1
Low, PA1
Pretto, G1
Westphal, GA1
Silva, E1
Drummond, PD1
Kim, HJ1
Seol, TK1
Lee, HJ1
Yaksh, TL1
Jun, JH1
Zhang, HG1
Li, XH1
Lyons, B1
Casey, W1
Doherty, P1
McHugh, M1
Moore, KP1
Viggiano, M1
Badetti, C1
Roux, F1
Mendizabal, H1
Bernini, V1
Manelli, JC1
Kariya, N1
Shindoh, M1
Nishi, S1
Yukioka, H1
Asada, A1
He, HM1
Sun, JW1
Xiao, CR1
Song, YN1
Cooper, R1
Wang, P1
Tao, JY3
Xu, SY3
Jiang, DJ1
Shi, J1

Reviews

1 review available for clonidine and Burns

ArticleYear
Anabolic and anticatabolic agents used in burn care: What is known and what is yet to be learned.
    Burns : journal of the International Society for Burn Injuries, 2020, Volume: 46, Issue:1

    Topics: Anabolic Agents; Burns; Clonidine; Growth Hormone-Releasing Hormone; Hormones; Human Growth Hormone;

2020

Trials

2 trials available for clonidine and Burns

ArticleYear
Clonidine for reduction of hemodynamic and psychological effects of S+ ketamine anesthesia for dressing changes in patients with major burns: an RCT.
    Burns : journal of the International Society for Burn Injuries, 2014, Volume: 40, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Anesthesia; Anesthetics, Dissociative; Anti-Anxiety Age

2014
[Controlled analgesia in a burn patient: fentanyl sparing effect of clonidine].
    Annales francaises d'anesthesie et de reanimation, 1998, Volume: 17, Issue:1

    Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Analgesia, Patient-Controlled; Burns; Clonidine; Doubl

1998

Other Studies

11 other studies available for clonidine and Burns

ArticleYear
Central hyperadrenergic state after lightning strike.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2013, Volume: 23, Issue:4

    Topics: Activities of Daily Living; Adrenergic alpha-Agonists; Anxiety; Arrhythmias, Cardiac; Autonomic Nerv

2013
alpha(1)-Adrenoceptors augment thermal hyperalgesia in mildly burnt skin.
    European journal of pain (London, England), 2009, Volume: 13, Issue:3

    Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adult; Burns; Clonidine; Female

2009
The effect of intrathecal mu, delta, kappa, and alpha-2 agonists on thermal hyperalgesia induced by mild burn on hind paw in rats.
    Journal of anesthesia, 2011, Volume: 25, Issue:6

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenergic

2011
[Effects of clonidine on myocardial Gs alpha mRNA expression after scalds in rats].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:1

    Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Burns; Clonidine; Cyclic AMP; Dose-Response Re

2002
Pain relief with low-dose intravenous clonidine in a child with severe burns.
    Intensive care medicine, 1996, Volume: 22, Issue:3

    Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Burns; Child; Clonidine; Drug Therapy, Combination; H

1996
Oral clonidine for sedation and analgesia in a burn patient.
    Journal of clinical anesthesia, 1998, Volume: 10, Issue:6

    Topics: Administration, Oral; Analgesics; Burns; Clonidine; Humans; Hypnotics and Sedatives; Ketamine; Male;

1998
Effects of clonidine on myocardial beta-adrenergic receptor-adenyl cyclase-cAMP system after scalds in rats.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:2

    Topics: Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Burns; Clonidin

1997
Clonidine in paediatric anaesthesia.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:2

    Topics: Analgesia, Epidural; Analgesics; Anesthetics, Local; Bupivacaine; Burns; Child, Preschool; Clonidine

2000
[Inhibitory effect of clonidine on hemolysis after thermal injury in animals].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1992, Volume: 13, Issue:1

    Topics: Animals; Burns; Clonidine; Glutathione; Glutathione Peroxidase; Hemolysis; Male; Mice; Norepinephrin

1992
[Inhibitory effects of clonidine on edema formation after thermal injury in mice and rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1989, Volume: 10, Issue:6

    Topics: Animals; Burns; Capillary Permeability; Clonidine; Edema; Lipid Peroxides; Male; Mice; Rats; Rats, I

1989
[Protective effects of clonidine on burn shock in mice and rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1987, Volume: 8, Issue:2

    Topics: Animals; Burns; Clonidine; Depression, Chemical; Female; Injections, Intraventricular; Male; Mice; R

1987