clonidine has been researched along with Bronchial Hyperreactivity in 3 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifteen patients with asthma were randomized into a double-blind, placebo controlled, crossover trial evaluating whether clonidine increased airway resistance." | 9.08 | Oral clonidine in patients with asthma: no significant effect on airway reactivity. ( Foxworth, JW; Knudson, SM; Pyszczynski, DR; Reisz, GR, 1995) |
| "Fifteen patients with asthma were randomized into a double-blind, placebo controlled, crossover trial evaluating whether clonidine increased airway resistance." | 5.08 | Oral clonidine in patients with asthma: no significant effect on airway reactivity. ( Foxworth, JW; Knudson, SM; Pyszczynski, DR; Reisz, GR, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamakage, M | 1 |
| Iwasaki, S | 1 |
| Satoh, JI | 1 |
| Namiki, A | 1 |
| Foxworth, JW | 1 |
| Reisz, GR | 1 |
| Pyszczynski, DR | 1 |
| Knudson, SM | 1 |
| Scott, GC | 1 |
| Chu, CS | 1 |
| Braun, SR | 1 |
2 trials available for clonidine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Oral clonidine in patients with asthma: no significant effect on airway reactivity.
Topics: Adult; Airway Resistance; Asthma; Blood Pressure; Bronchial Hyperreactivity; Clonidine; Cross-Over S | 1995 |
Transdermal delivery of the alpha 2-agonist clonidine does not alter airways responses to inhaled histamine or methacholine.
Topics: Administration, Cutaneous; Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Br | 1991 |
1 other study available for clonidine and Bronchial Hyperreactivity
| Article | Year |
|---|---|
Inhibitory effects of the alpha-2 adrenergic agonists clonidine and dexmedetomidine on enhanced airway tone in ovalbumin-sensitized guinea pigs.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Airway Obstruction; Animals; Bronchial Hyperreactivity; Ca | 2008 |