clonidine has been researched along with Breast Cancer in 30 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In all, 102 patients with a history of breast cancer were randomly assigned (2:2:1) to venlafaxine 75 mg, clonidine 0." | 9.15 | Management of hot flashes in patients who have breast cancer with venlafaxine and clonidine: a randomized, double-blind, placebo-controlled trial. ( Adriaansz, S; Beijnen, JH; Boekhout, AH; Dalesio, OB; Foekema-Töns, JH; Nuijen, B; Schellens, JH; Sprangers, S; van den Bosch, J; Vincent, AD, 2011) |
| "In a double-blind, cross-over study, 60 breast cancer patients experiencing HF were randomized to 8 weeks venlafaxine followed by 2 weeks wash-out, and 8 weeks clonidine or vice versa." | 9.14 | Venlafaxine versus clonidine for the treatment of hot flashes in breast cancer patients: a double-blind, randomized cross-over study. ( Buijs, C; de Jong, RS; de Vries, EG; Marike Boezen, H; Maurer, JM; Mom, CH; Mourits, MJ; Nieboer, P; Willemse, PH; Wymenga, AN, 2009) |
| "In a double-blind, randomized phase III study, breast cancer patients suffering from hot flashes at least twice a day, who were not taking any medication against hypertension and depression received either clonidine 0." | 9.12 | Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients--a double-blind, randomized study. ( Kaufmann, M; Loibl, S; Mehta, KM; Schwedler, K; Strohmeier, R; von Minckwitz, G, 2007) |
| " Our hypothesis is that coinduction with clonidine reduces the incidence of PONV in adult patients undergoing breast cancer surgery." | 9.10 | Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. ( Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Muhrbeck, O; Oddby-Muhrbeck, E, 2002) |
| "Patients in the placebo and treatment groups were similar in age, duration of tamoxifen use, reported frequency and duration of hot flashes at baseline, and dropout rates." | 9.09 | Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifen-induced hot flashes: a University of Rochester Cancer Center Community Clinical Oncology Program study. ( Dragalin, V; Flynn, PJ; Hynes, HE; Kirshner, JJ; Morrow, GR; Pandya, KJ; Pierce, HI; Raubertas, RF; Rosenbluth, RJ, 2000) |
| "A 62-year-old white woman with stage 3 breast cancer metastatic to the spine and a history of hypertension received a combined injection of hydromorphone 48." | 7.70 | Hypertensive crisis and myocardial infarction following massive clonidine overdose. ( Frye, CB; Vance, MA, 2000) |
| "In all, 102 patients with a history of breast cancer were randomly assigned (2:2:1) to venlafaxine 75 mg, clonidine 0." | 5.15 | Management of hot flashes in patients who have breast cancer with venlafaxine and clonidine: a randomized, double-blind, placebo-controlled trial. ( Adriaansz, S; Beijnen, JH; Boekhout, AH; Dalesio, OB; Foekema-Töns, JH; Nuijen, B; Schellens, JH; Sprangers, S; van den Bosch, J; Vincent, AD, 2011) |
| "In a double-blind, cross-over study, 60 breast cancer patients experiencing HF were randomized to 8 weeks venlafaxine followed by 2 weeks wash-out, and 8 weeks clonidine or vice versa." | 5.14 | Venlafaxine versus clonidine for the treatment of hot flashes in breast cancer patients: a double-blind, randomized cross-over study. ( Buijs, C; de Jong, RS; de Vries, EG; Marike Boezen, H; Maurer, JM; Mom, CH; Mourits, MJ; Nieboer, P; Willemse, PH; Wymenga, AN, 2009) |
| "In a double-blind, randomized phase III study, breast cancer patients suffering from hot flashes at least twice a day, who were not taking any medication against hypertension and depression received either clonidine 0." | 5.12 | Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients--a double-blind, randomized study. ( Kaufmann, M; Loibl, S; Mehta, KM; Schwedler, K; Strohmeier, R; von Minckwitz, G, 2007) |
| " Our hypothesis is that coinduction with clonidine reduces the incidence of PONV in adult patients undergoing breast cancer surgery." | 5.10 | Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. ( Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Muhrbeck, O; Oddby-Muhrbeck, E, 2002) |
| "Patients in the placebo and treatment groups were similar in age, duration of tamoxifen use, reported frequency and duration of hot flashes at baseline, and dropout rates." | 5.09 | Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifen-induced hot flashes: a University of Rochester Cancer Center Community Clinical Oncology Program study. ( Dragalin, V; Flynn, PJ; Hynes, HE; Kirshner, JJ; Morrow, GR; Pandya, KJ; Pierce, HI; Raubertas, RF; Rosenbluth, RJ, 2000) |
| " After evaluating the sedation and anxiety levels of patients using a visual analog scale, anesthesia was induced with propofol (1." | 5.08 | The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia. ( Imai, Y; Kagawa, K; Kirita, T; Kishi, Y; Kita, T; Mammoto, T; Murakami, K; Sakai, T; Sugimura, M, 1998) |
| " Women with a history of breast cancer who were receiving tamoxifen and suffering from hot flashes were potentially eligible for this protocol study." | 5.07 | Transdermal clonidine for ameliorating tamoxifen-induced hot flashes. ( Burnham, NL; Dose, AM; Goldberg, RM; Loprinzi, CL; Mailliard, JA; Michalak, JC; Miser, AW; O'Fallon, JR; Rowland, KM; Veeder, MH, 1994) |
| "Clonidine, SSRIs and SNRIs, gabapentin and relaxation therapy showed a mild to moderate effect on reducing hot flushes in women with a history of breast cancer." | 4.86 | Non-hormonal interventions for hot flushes in women with a history of breast cancer. ( Capurro, D; Corbalán, J; Letelier, LM; Moreno, G; Pantoja, T; Rada, G; Vera, C, 2010) |
| "A 62-year-old white woman with stage 3 breast cancer metastatic to the spine and a history of hypertension received a combined injection of hydromorphone 48." | 3.70 | Hypertensive crisis and myocardial infarction following massive clonidine overdose. ( Frye, CB; Vance, MA, 2000) |
| "The frequency of neuropathic pain was assessed using the Douleur Neuropathique 4-question survey (DN4) in the first and second postoperative months." | 2.78 | Effect of the addition of clonidine to locally administered bupivacaine on acute and chronic postmastectomy pain. ( Abdel-Ghaffar, HS; Mohamed, SA, 2013) |
| "A third of female patients with cancer report dissatisfaction with the quality and length of physician-patient discussions about reproductive health, including menopause." | 2.58 | Managing menopausal symptoms after cancer: an evidence-based approach for primary care. ( Hickey, M; Marino, JL; McNamara, HC, 2018) |
| "Breast cancer is the most common newly diagnosed cancer in women." | 2.43 | Therapy for menopausal symptoms during and after treatment for breast cancer : safety considerations. ( Baber, R; Hickey, M; Kwik, M, 2005) |
| "Breast cancer is the most common cancer in women, and mastectomy is commonly performed as part of the management." | 1.43 | The effect of serratus plane block performed under direct vision on postoperative pain in breast surgery. ( Babar, M; Davies, G; Harada, A; Hards, M; Harwell, S; Neville, I; Ravalia, A, 2016) |
| "Women affected by breast cancer (BC) will often go through menopause at an earlier age and display more frequent and severe symptoms than women who have a natural menopause." | 1.40 | Treatment of climacteric symptoms in breast cancer patients: a retrospective study from a medication databank. ( Ameye, L; Antoine, C; Paesmans, M; Rozenberg, S, 2014) |
| "Five patients who underwent surgery for breast cancer were followed for 6 days after placement of a multiple-injection, one-time paravertebral block." | 1.38 | A case series of thoracic paravertebral blocks using a combination of ropivacaine, clonidine, epinephrine, and dexamethasone. ( Berger, JS; French, KE; Goravanchi, F; Kee, SS; Kowalski, AM, 2012) |
| "Menopausal symptom management after breast cancer may be complex, and we present a novel model of care using a multidisciplinary approach." | 1.36 | The multidisciplinary management of menopausal symptoms after breast cancer: a unique model of care. ( Doherty, DA; Emery, LI; Gregson, J; Hickey, M; Saunders, CM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.33) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 17 (56.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woyka, J | 1 |
| Marino, JL | 1 |
| McNamara, HC | 1 |
| Hickey, M | 3 |
| Forget, P | 1 |
| Berlière, M | 1 |
| Poncelet, A | 1 |
| De Kock, M | 1 |
| Naja, ZM | 1 |
| Ziade, FM | 1 |
| El-Rajab, MA | 1 |
| Naccash, N | 1 |
| Ayoubi, JM | 1 |
| Antoine, C | 1 |
| Ameye, L | 1 |
| Paesmans, M | 1 |
| Rozenberg, S | 1 |
| Eden, J | 1 |
| Hards, M | 1 |
| Harada, A | 1 |
| Neville, I | 1 |
| Harwell, S | 1 |
| Babar, M | 1 |
| Ravalia, A | 1 |
| Davies, G | 1 |
| Buijs, C | 1 |
| Mom, CH | 1 |
| Willemse, PH | 1 |
| Marike Boezen, H | 1 |
| Maurer, JM | 1 |
| Wymenga, AN | 1 |
| de Jong, RS | 1 |
| Nieboer, P | 1 |
| de Vries, EG | 1 |
| Mourits, MJ | 1 |
| Kontos, M | 1 |
| Agbaje, OF | 1 |
| Rymer, J | 1 |
| Fentiman, IS | 1 |
| Friedman, GD | 1 |
| Udaltsova, N | 1 |
| Habel, LA | 1 |
| Emery, LI | 1 |
| Gregson, J | 1 |
| Doherty, DA | 1 |
| Saunders, CM | 1 |
| Rada, G | 1 |
| Capurro, D | 1 |
| Pantoja, T | 1 |
| Corbalán, J | 1 |
| Moreno, G | 1 |
| Letelier, LM | 1 |
| Vera, C | 1 |
| Bruzzone, A | 1 |
| Piñero, CP | 1 |
| Rojas, P | 1 |
| Romanato, M | 1 |
| Gass, H | 1 |
| Lanari, C | 1 |
| Lüthy, IA | 2 |
| Boekhout, AH | 1 |
| Vincent, AD | 1 |
| Dalesio, OB | 1 |
| van den Bosch, J | 1 |
| Foekema-Töns, JH | 1 |
| Adriaansz, S | 1 |
| Sprangers, S | 1 |
| Nuijen, B | 1 |
| Beijnen, JH | 1 |
| Schellens, JH | 1 |
| Loprinzi, CL | 3 |
| Barton, DL | 2 |
| Qin, R | 1 |
| Goravanchi, F | 1 |
| Kee, SS | 1 |
| Kowalski, AM | 1 |
| Berger, JS | 1 |
| French, KE | 1 |
| Lefkowits, CC | 1 |
| Arnold, RM | 1 |
| Mohamed, SA | 1 |
| Abdel-Ghaffar, HS | 1 |
| Baber, R | 1 |
| Kwik, M | 1 |
| Burlacu, CL | 1 |
| Frizelle, HP | 1 |
| Moriarty, DC | 1 |
| Buggy, DJ | 1 |
| Loibl, S | 1 |
| Schwedler, K | 1 |
| von Minckwitz, G | 1 |
| Strohmeier, R | 1 |
| Mehta, KM | 1 |
| Kaufmann, M | 1 |
| Goldberg, RM | 1 |
| O'Fallon, JR | 1 |
| Veeder, MH | 1 |
| Miser, AW | 1 |
| Mailliard, JA | 1 |
| Michalak, JC | 1 |
| Dose, AM | 1 |
| Rowland, KM | 1 |
| Burnham, NL | 1 |
| Imai, Y | 1 |
| Mammoto, T | 1 |
| Murakami, K | 1 |
| Kita, T | 1 |
| Sakai, T | 1 |
| Kagawa, K | 1 |
| Kirita, T | 1 |
| Sugimura, M | 1 |
| Kishi, Y | 1 |
| Vázquez, SM | 1 |
| Pignataro, O | 1 |
| Pandya, KJ | 1 |
| Raubertas, RF | 1 |
| Flynn, PJ | 1 |
| Hynes, HE | 1 |
| Rosenbluth, RJ | 1 |
| Kirshner, JJ | 1 |
| Pierce, HI | 1 |
| Dragalin, V | 1 |
| Morrow, GR | 1 |
| Frye, CB | 1 |
| Vance, MA | 1 |
| Leong, MS | 1 |
| Calabrese, JF | 1 |
| Heit, G | 1 |
| Rhodes, D | 1 |
| Oddby-Muhrbeck, E | 1 |
| Eksborg, S | 1 |
| Bergendahl, HT | 1 |
| Muhrbeck, O | 1 |
| Lönnqvist, PA | 1 |
| Plowman, PN | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparative Study for Evaluation of the Analgesic Profile of Ultrasound-Guided Modified Pectoral Nerves Block Versus Serratus Plane Block in Major Breast Cancer Surgery[NCT02946294] | Phase 2 | 90 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for clonidine and Breast Cancer
| Article | Year |
|---|---|
Managing menopausal symptoms after cancer: an evidence-based approach for primary care.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Amenorrhea; Anti-Anxiety Agents; Breast Neoplasms; Canc | 2018 |
ENDOCRINE DILEMMA: Managing menopausal symptoms after breast cancer.
Topics: Administration, Intravaginal; Administration, Topical; Atrophy; Bone Density Conservation Agents; Br | 2016 |
What can be done about hot flushes after treatment for breast cancer?
Topics: Amines; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Clonidine; Complementary Therapies; Cyclo | 2010 |
Non-hormonal interventions for hot flushes in women with a history of breast cancer.
Topics: Acupuncture Therapy; Amines; Breast Neoplasms; Clonidine; Cyclohexanecarboxylic Acids; Excitatory Am | 2010 |
Therapy for menopausal symptoms during and after treatment for breast cancer : safety considerations.
Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Case-Control Studies; Clonidine; Estrogen Recepto | 2005 |
Management of hot flashes in breast-cancer survivors.
Topics: Antidepressive Agents; Belladonna Alkaloids; Breast Neoplasms; Clonidine; Drug Combinations; Ergotam | 2001 |
10 trials available for clonidine and Breast Cancer
| Article | Year |
|---|---|
Guided paravertebral blocks with versus without clonidine for women undergoing breast surgery: a prospective double-blinded randomized study.
Topics: Breast Neoplasms; Clonidine; Double-Blind Method; Female; Humans; Mastectomy; Middle Aged; Monitorin | 2013 |
Venlafaxine versus clonidine for the treatment of hot flashes in breast cancer patients: a double-blind, randomized cross-over study.
Topics: Adrenergic alpha-Agonists; Adult; Breast Neoplasms; Clonidine; Cross-Over Studies; Cyclohexanols; Do | 2009 |
Management of hot flashes in patients who have breast cancer with venlafaxine and clonidine: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Aged; Analgesics; Breast Neoplasms; Clonidine; Cyclohexanols; Double-Blind Method; Female; Ho | 2011 |
Effect of the addition of clonidine to locally administered bupivacaine on acute and chronic postmastectomy pain.
Topics: Acute Pain; Administration, Topical; Adult; Analgesics; Anesthetics, Local; Breast Neoplasms; Bupiva | 2013 |
Fentanyl and clonidine as adjunctive analgesics with levobupivacaine in paravertebral analgesia for breast surgery.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Breast Neoplasms; Bupiva | 2006 |
Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients--a double-blind, randomized study.
Topics: Adult; Aged; Breast Neoplasms; Clonidine; Cyclohexanols; Double-Blind Method; Female; Hot Flashes; H | 2007 |
Transdermal clonidine for ameliorating tamoxifen-induced hot flashes.
Topics: Administration, Cutaneous; Breast Neoplasms; Climacteric; Clonidine; Double-Blind Method; Female; Hu | 1994 |
The effects of preanesthetic oral clonidine on total requirement of propofol for general anesthesia.
Topics: Administration, Oral; Adult; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; | 1998 |
Oral clonidine in postmenopausal patients with breast cancer experiencing tamoxifen-induced hot flashes: a University of Rochester Cancer Center Community Clinical Oncology Program study.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; | 2000 |
Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anesthesia, General; Antiemetics; Blood Pressure; Breast Neoplasms; | 2002 |
14 other studies available for clonidine and Breast Cancer
| Article | Year |
|---|---|
Consensus statement for non-hormonal-based treatments for menopausal symptoms.
Topics: Amines; Anticonvulsants; Antihypertensive Agents; Behavior Therapy; Breast Neoplasms; Clonidine; Con | 2017 |
Effect of clonidine on oncological outcomes after breast and lung cancer surgery.
Topics: Animals; Breast Neoplasms; Clonidine; Colonic Neoplasms; Dexmedetomidine; Humans; Lung Neoplasms; Ro | 2018 |
Treatment of climacteric symptoms in breast cancer patients: a retrospective study from a medication databank.
Topics: Aged; Amines; Antidepressive Agents; Antineoplastic Agents; Aromatase Inhibitors; Belgium; Breast Ne | 2014 |
The effect of serratus plane block performed under direct vision on postoperative pain in breast surgery.
Topics: Analgesics; Anesthesia, Local; Anesthetics, Local; Breast Neoplasms; Bupivacaine; Clonidine; Female; | 2016 |
Norepinephrine antagonists and cancer risk.
Topics: Atenolol; Breast Neoplasms; Clonidine; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Male; Meto | 2011 |
The multidisciplinary management of menopausal symptoms after breast cancer: a unique model of care.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Amines; Anti-Anxiety Agents; Breast Neop | 2010 |
α(2)-Adrenoceptors enhance cell proliferation and mammary tumor growth acting through both the stroma and the tumor cells.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Breast Neopl | 2011 |
Nonestrogenic management of hot flashes.
Topics: Breast Neoplasms; Clonidine; Cyclohexanols; Female; Hot Flashes; Humans; Venlafaxine Hydrochloride | 2011 |
A case series of thoracic paravertebral blocks using a combination of ropivacaine, clonidine, epinephrine, and dexamethasone.
Topics: Amides; Analgesics; Anesthetics, Combined; Anesthetics, Local; Breast Neoplasms; Clonidine; Dexameth | 2012 |
Hot flashes in palliative care. Part 2 #262.
Topics: Amines; Analgesics; Antineoplastic Agents, Hormonal; Breast Neoplasms; Clonidine; Cyclohexanecarboxy | 2013 |
Alpha2-adrenergic effect on human breast cancer MCF-7 cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Breast Neoplas | 1999 |
Hypertensive crisis and myocardial infarction following massive clonidine overdose.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Breast Neoplasms; Clonidine; Drug Overdose; Drug Ther | 2000 |
Intraventricular administration of morphine and clonidine.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Brain Neoplasms; Breast Neoplasms; Carcinoma, Ductal, | 2001 |
Treatment of menopausal symptoms in breast cancer patients.
Topics: Breast Neoplasms; Climacteric; Clonidine; Female; Humans; Norethindrone | 1988 |