clonidine has been researched along with Brain Swelling in 6 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that early and unselective beta-blockade with propranolol alone or in combination with the alfa2-agonist clonidine would decrease brain edema, blood-brain barrier permeability, and glycocalyx disruption at 24 hours after trauma." | 7.88 | Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat. ( Bentzer, P; Genét, GF; Hansen, MB; Johansson, PI; Ostrowski, SR, 2018) |
| " We hypothesized that early and unselective beta-blockade with propranolol alone or in combination with the alfa2-agonist clonidine would decrease brain edema, blood-brain barrier permeability, and glycocalyx disruption at 24 hours after trauma." | 3.88 | Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat. ( Bentzer, P; Genét, GF; Hansen, MB; Johansson, PI; Ostrowski, SR, 2018) |
| "Clonidine and yohimbine were intraperitoneally given to the rats each day for a week before ischemia." | 1.43 | Clonidine preconditioning alleviated focal cerebral ischemic insult in rats via up-regulating p-NMDAR1 and down-regulating NMDAR2A / p-NMDAR2B. ( Bo, Z; Lingling, Y; Min, Z; Xizhou, Z; Yan, W; Yanli, L; Yunhong, Z; Zhangao, C; Zhi, H; Zicheng, L, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Genét, GF | 1 |
| Bentzer, P | 1 |
| Hansen, MB | 1 |
| Ostrowski, SR | 1 |
| Johansson, PI | 1 |
| Yanli, L | 1 |
| Xizhou, Z | 1 |
| Yan, W | 1 |
| Bo, Z | 1 |
| Yunhong, Z | 1 |
| Zicheng, L | 1 |
| Lingling, Y | 2 |
| Zhangao, C | 1 |
| Min, Z | 1 |
| Zhi, H | 1 |
| Sansing, LH | 1 |
| Messe, SR | 1 |
| Cucchiara, BL | 1 |
| Lyden, PD | 1 |
| Kasner, SE | 1 |
| Jugé, M | 2 |
| Grimaud, N | 2 |
| Petit, JY | 2 |
| Robert, B | 1 |
| Welin, L | 1 |
| Philipp, T | 1 |
| Nast, HP | 1 |
1 trial available for clonidine and Brain Swelling
| Article | Year |
|---|---|
Anti-adrenergic medications and edema development after intracerebral hemorrhage.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; An | 2011 |
5 other studies available for clonidine and Brain Swelling
| Article | Year |
|---|---|
Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Blood-Brain Barrier; Bra | 2018 |
Clonidine preconditioning alleviated focal cerebral ischemic insult in rats via up-regulating p-NMDAR1 and down-regulating NMDAR2A / p-NMDAR2B.
Topics: Animals; Brain Edema; Clonidine; Down-Regulation; Infarction, Middle Cerebral Artery; Ischemic Preco | 2016 |
Involvement of alpha2-adrenergic mechanisms in experimental analgesic and anti-inflammatory activities of a benzamide derivative.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzamides; Blood Press | 1997 |
Effect of clonidine on experimental brain edema in the rat.
Topics: Animals; Blood Pressure; Brain; Brain Edema; Clonidine; Copper; Dexamethasone; Indomethacin; Male; P | 1992 |
[Hypertensive emergencies].
Topics: Brain Edema; Clonidine; Diazoxide; Digitalis Glycosides; Diuretics; Drug Combinations; Emergencies; | 1974 |