clonidine has been researched along with Blood Poisoning in 6 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of clonidine during hypotensive sepsis reduced renal sympathetic nerve activity, restored vascular sensitivity to both phenylephrine and angiotensin II, and resulted in better preservation of arterial pressure." | 7.81 | Clonidine Restores Pressor Responsiveness to Phenylephrine and Angiotensin II in Ovine Sepsis. ( Bellomo, R; Booth, LC; Evans, RG; Kosaka, J; Lankadeva, YR; May, CN; Quintin, L, 2015) |
| " Presently, the most robust clinical evidence involves the use of the cardioselective β-blocker esmolol in patients with septic shock with persistent tachycardia secondary to catecholamine use." | 4.98 | Misdirected Sympathy: The Role of Sympatholysis in Sepsis and Septic Shock. ( Bissell, BD; Ferreira, JA, 2018) |
| "Administration of clonidine during hypotensive sepsis reduced renal sympathetic nerve activity, restored vascular sensitivity to both phenylephrine and angiotensin II, and resulted in better preservation of arterial pressure." | 3.81 | Clonidine Restores Pressor Responsiveness to Phenylephrine and Angiotensin II in Ovine Sepsis. ( Bellomo, R; Booth, LC; Evans, RG; Kosaka, J; Lankadeva, YR; May, CN; Quintin, L, 2015) |
| "With early trauma, beta-adrenergic responsiveness and receptor number were significantly decreased." | 1.27 | Adrenergic control of adipocyte lipolysis in trauma and sepsis. ( Askanazi, J; Forse, RA; Hirsch, J; Kinney, JM; Leibel, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Lankadeva, YR | 2 |
| Shehabi, Y | 1 |
| Deane, AM | 1 |
| Plummer, MP | 1 |
| Bellomo, R | 2 |
| May, CN | 2 |
| Booth, LC | 1 |
| Kosaka, J | 1 |
| Evans, RG | 1 |
| Quintin, L | 2 |
| Gradwohl-Matis, I | 1 |
| Dünser, MW | 1 |
| Geloën, A | 1 |
| Ferreira, JA | 1 |
| Bissell, BD | 1 |
| Forse, RA | 1 |
| Leibel, R | 1 |
| Askanazi, J | 1 |
| Hirsch, J | 1 |
| Kinney, JM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study to Quantify the Autonomic Nervous System Balance in Healthy, Able-Bodied Individuals[NCT04100486] | 48 participants (Anticipated) | Observational | 2019-08-29 | Enrolling by invitation | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for clonidine and Blood Poisoning
| Article | Year |
|---|---|
Emerging benefits and drawbacks of α
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonists; Clonidine; Critical Illness; Dexmed | 2021 |
Misdirected Sympathy: The Role of Sympatholysis in Sepsis and Septic Shock.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Animals; Catecholamine | 2018 |
4 other studies available for clonidine and Blood Poisoning
| Article | Year |
|---|---|
Clonidine Restores Pressor Responsiveness to Phenylephrine and Angiotensin II in Ovine Sepsis.
Topics: Adrenergic alpha-2 Receptor Agonists; Angiotensin II; Animals; Blood Pressure; Clonidine; Female; Hy | 2015 |
Reverse Physiology: Applying an Antihypertensive Drug to Increase Arterial Blood Pressure in Septic Shock.
Topics: Adrenergic alpha-2 Receptor Agonists; Angiotensin II; Animals; Blood Pressure; Clonidine; Female; Hy | 2015 |
Reverse Physiology, i.e., Cellular Versus Integrative Versus Comparative Physiology? α-2 Agonists and Septic Shock.
Topics: Adrenergic alpha-2 Receptor Agonists; Angiotensin II; Animals; Blood Pressure; Clonidine; Female; Hy | 2016 |
Adrenergic control of adipocyte lipolysis in trauma and sepsis.
Topics: Adipose Tissue; Adult; Aged; Clonidine; Energy Metabolism; Female; Humans; Isoproterenol; Lipolysis; | 1987 |