Page last updated: 2024-10-25

clonidine and Blood Loss, Surgical

clonidine has been researched along with Blood Loss, Surgical in 13 studies

Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.

Blood Loss, Surgical: Loss of blood during a surgical procedure.

Research Excerpts

ExcerptRelevanceReference
"2% and apraclonidine 1%) are useful alternatives to topical adrenaline (epinephrine) in adjustable suture strabismus surgery."9.14Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery. ( Bailly, M; Cosgrave, E; Dahlmann-Noor, AH; Lowe, S; Vivian, AJ, 2009)
"Nonselective beta blockade (BB) and clonidine may abrogate catecholamine-mediated persistent injury-associated anemia."7.88The effects of beta blockade and clonidine on persistent injury-associated anemia. ( Brakenridge, SC; Croft, CA; Efron, PA; Loftus, TJ; Mohr, AM; Moore, FA; Rosenthal, MD; Smith, RS, 2018)
"To find out the efficacy and safety of clonidine in reducing blood loss in pituitary adenoma surgery through a randomized masked trial."7.85Preoperative clonidine use in trans-sphenoidal pituitary adenoma surgeries - a randomized controlled trial. ( Bajaj, J; Mittal, RS; Sharma, A, 2017)
"A group of 44 patients undergoing FESS for chronic sinusitis and polyp removal were enrolled and randomly assigned to receive either oral clonidine or midazolam as preoperative premedication."5.17Premedication with clonidine before TIVA optimizes surgical field visualization and shortens duration of endoscopic sinus surgery - results of a clinical trial. ( Burduk, PK; Cywinski, JB; Kazmierczak, W; Kusza, K; Wawrzyniak, K, 2013)
"2% and apraclonidine 1%) are useful alternatives to topical adrenaline (epinephrine) in adjustable suture strabismus surgery."5.14Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery. ( Bailly, M; Cosgrave, E; Dahlmann-Noor, AH; Lowe, S; Vivian, AJ, 2009)
"Nonselective beta blockade (BB) and clonidine may abrogate catecholamine-mediated persistent injury-associated anemia."3.88The effects of beta blockade and clonidine on persistent injury-associated anemia. ( Brakenridge, SC; Croft, CA; Efron, PA; Loftus, TJ; Mohr, AM; Moore, FA; Rosenthal, MD; Smith, RS, 2018)
"To find out the efficacy and safety of clonidine in reducing blood loss in pituitary adenoma surgery through a randomized masked trial."3.85Preoperative clonidine use in trans-sphenoidal pituitary adenoma surgeries - a randomized controlled trial. ( Bajaj, J; Mittal, RS; Sharma, A, 2017)
"Clonidine is an antihypertensive agent used for induced hypotension."2.82Effects of oral clonidine premedication on hemodynamic status in bimaxillary orthognathic surgery: A double-blind randomized clinical trial. ( Khakbaz, O; Marashi, M; Mohammadi, F; Tavakoli, I, 2016)
"Four clonidine-treated patients required urapidil to achieve satisfactory hypotension as compared with 11 controls (P<0."2.70Clonidine decreases intraoperative bleeding in middle ear microsurgery. ( Delgado-Martinez, AD; Gómez-Luque, A; Marchal, JM; Martínez-López, MC; Martos-Crespo, F; Sánchez De La Cuesta, F, 2001)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's9 (69.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Loftus, TJ1
Rosenthal, MD1
Croft, CA1
Smith, RS1
Moore, FA1
Brakenridge, SC1
Efron, PA1
Mohr, AM1
Escamilla, Y3
Cardesín, A3
Samara, L1
López, S1
Izquierdo, A1
Fradera, M1
Vives, R1
Bernal-Sprekelsen, M3
Pontes, C3
Wawrzyniak, K1
Kusza, K1
Cywinski, JB1
Burduk, PK1
Kazmierczak, W1
Rosell, R2
Marco, J2
Escobar, MJ2
Tabrizi, R1
Eftekharian, H1
Pourdanesh, F1
Khaghaninejad, MS1
Mohammadi, F1
Marashi, M1
Tavakoli, I1
Khakbaz, O1
Bajaj, J1
Mittal, RS1
Sharma, A1
Dahlmann-Noor, AH1
Cosgrave, E1
Lowe, S1
Bailly, M1
Vivian, AJ1
Mohseni, M1
Ebneshahidi, A1
Okuyama, K1
Inomata, S1
Toyooka, H1
Marchal, JM1
Gómez-Luque, A1
Martos-Crespo, F1
Sánchez De La Cuesta, F1
Martínez-López, MC1
Delgado-Martinez, AD1
Welfringer, P1
Manel, J1
Garric, J1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparative Study of Influence of Surgical Pleth Index Guided Total Intravenous Anaesthesia (TIVA) or Volatile Anaesthesia Using Sevoflurane or Desflurane on the Intraoperative Blood Loss During Functional Endoscopic Sinus Surgery[NCT03417180]120 participants (Anticipated)Interventional2018-09-01Recruiting
Comparative Study of Influence of Total Intravenous Anaesthesia (TIVA) and Volatile Anaesthesia Using Sevoflurane or Desflurane on the Intraoperative Blood Loss During Functional Endoscopic Sinus Surgery[NCT03417206]120 participants (Anticipated)Interventional2021-09-01Not yet recruiting
Comparative Study of Influence of Different Techniques of Remifentanil Titration During Functional Endoscopic Sinus Surgery Under Total Intravenous Anaesthesia (TIVA)[NCT03389763]105 participants (Actual)Interventional2016-06-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for clonidine and Blood Loss, Surgical

ArticleYear
[Clonidine premedication and isoflurane anesthesia to reduce bleeding in otologic surgery].
    Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2

    Topics: Adult; Blood Loss, Surgical; Clonidine; Drug Synergism; Ear; Female; Hemodynamics; Humans; Hypotensi

1992

Trials

10 trials available for clonidine and Blood Loss, Surgical

ArticleYear
Randomized clinical trial to compare the efficacy to improve the quality of surgical field of hypotensive anesthesia with clonidine or dexmedetomidine during functional endoscopic sinus surgery.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019, Volume: 276, Issue:11

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Blood Loss, Surgical; Chronic Disease; Clonidine;

2019
Premedication with clonidine before TIVA optimizes surgical field visualization and shortens duration of endoscopic sinus surgery - results of a clinical trial.
    Rhinology, 2013, Volume: 51, Issue:3

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Blood Loss, Surgical; Chronic Disease; Clonidine;

2013
Does oral clonidine premedication decrease bleeding during open rhinoplasty?
    The Journal of craniofacial surgery, 2014, Volume: 25, Issue:3

    Topics: Administration, Oral; Adrenergic alpha-2 Receptor Agonists; Adult; Blood Loss, Surgical; Blood Press

2014
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
A randomised double blind clinical trial to compare surgical field bleeding during endoscopic sinus surgery with clonidine-based or remifentanil-based hypotensive anaesthesia.
    Rhinology, 2015, Volume: 53, Issue:2

    Topics: Anesthetics, Intravenous; Antihypertensive Agents; Blood Loss, Surgical; Clonidine; Double-Blind Met

2015
Effects of oral clonidine premedication on hemodynamic status in bimaxillary orthognathic surgery: A double-blind randomized clinical trial.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2016, Volume: 44, Issue:4

    Topics: Adult; Blood Loss, Surgical; Clonidine; Double-Blind Method; Female; Hemodynamics; Humans; Male; Ort

2016
Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2009, Volume: 13, Issue:2

    Topics: Adrenergic alpha-Agonists; Adult; Blood Loss, Surgical; Brimonidine Tartrate; Clonidine; Combined Mo

2009
The effect of oral clonidine premedication on blood loss and the quality of the surgical field during endoscopic sinus surgery: a placebo-controlled clinical trial.
    Journal of anesthesia, 2011, Volume: 25, Issue:4

    Topics: Adult; Anesthesia; Blood Loss, Surgical; Clonidine; Endoscopy; Female; Humans; Male; Placebos; Preme

2011
The effects of prostaglandin E1 or oral clonidine premedication on blood loss during paranasal sinus surgery.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2005, Volume: 52, Issue:5

    Topics: Administration, Oral; Alprostadil; Blood Loss, Surgical; Blood Pressure; Clonidine; Humans; Paranasa

2005
Clonidine decreases intraoperative bleeding in middle ear microsurgery.
    Acta anaesthesiologica Scandinavica, 2001, Volume: 45, Issue:5

    Topics: Adrenergic alpha-Agonists; Adult; Analgesics; Blood Loss, Surgical; Clonidine; Double-Blind Method;

2001
[Clonidine premedication and isoflurane anesthesia to reduce bleeding in otologic surgery].
    Annales francaises d'anesthesie et de reanimation, 1992, Volume: 11, Issue:2

    Topics: Adult; Blood Loss, Surgical; Clonidine; Drug Synergism; Ear; Female; Hemodynamics; Humans; Hypotensi

1992

Other Studies

3 other studies available for clonidine and Blood Loss, Surgical

ArticleYear
The effects of beta blockade and clonidine on persistent injury-associated anemia.
    The Journal of surgical research, 2018, Volume: 230

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Age Factors; Anemia; Blood Loss,

2018
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Hypotensive anaesthesia and bleeding during endoscopic sinus surgery: an observational study.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Anesthesia, General; Blo

2014
Preoperative clonidine use in trans-sphenoidal pituitary adenoma surgeries - a randomized controlled trial.
    British journal of neurosurgery, 2017, Volume: 31, Issue:1

    Topics: Adenoma; Adrenergic alpha-Agonists; Adult; Blood Loss, Surgical; Clonidine; Double-Blind Method; Fem

2017