clonidine has been researched along with Bleeding in 16 studies
Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION.
clonidine (amino form) : A clonidine that is 4,5-dihydro-1H-imidazol-2-amine in which one of the amino hydrogens is replaced by a 2,6-dichlorophenyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (56.25) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Miller, DL | 1 |
| Dou, C | 1 |
| Raghavendran, K | 1 |
| Dong, Z | 1 |
| Graham, MM | 1 |
| Sessler, DI | 2 |
| Parlow, JL | 1 |
| Biccard, BM | 1 |
| Guyatt, G | 1 |
| Leslie, K | 2 |
| Chan, MTV | 1 |
| Meyhoff, CS | 2 |
| Xavier, D | 1 |
| Sigamani, A | 1 |
| Kumar, PA | 1 |
| Mrkobrada, M | 2 |
| Cook, DJ | 1 |
| Tandon, V | 1 |
| Alvarez-Garcia, J | 1 |
| Villar, JC | 2 |
| Painter, TW | 1 |
| Landoni, G | 1 |
| Fleischmann, E | 2 |
| Lamy, A | 1 |
| Whitlock, R | 2 |
| Le Manach, Y | 1 |
| Aphang-Lam, M | 1 |
| Cata, JP | 2 |
| Gao, P | 1 |
| Terblanche, NCS | 1 |
| Ramana, PV | 1 |
| Jamieson, KA | 1 |
| Bessissow, A | 1 |
| Mendoza, GR | 1 |
| Ramirez, S | 1 |
| Diemunsch, PA | 1 |
| Yusuf, S | 2 |
| Devereaux, PJ | 2 |
| Wawrzyniak, K | 1 |
| Burduk, PK | 1 |
| Cywinski, JB | 1 |
| Kusza, K | 1 |
| Kazmierczak, W | 1 |
| Garg, AX | 1 |
| Kurz, A | 1 |
| Cuerden, M | 1 |
| Robinson, A | 1 |
| Parikh, CR | 1 |
| Mizera, R | 1 |
| Jones, PM | 1 |
| Tiboni, M | 1 |
| Font, A | 1 |
| Cegarra, V | 1 |
| Gomez, MF | 1 |
| VanHelder, T | 1 |
| Chan, MT | 1 |
| Torres, D | 1 |
| Parlow, J | 1 |
| Clanchet, Mde N | 1 |
| Amir, M | 1 |
| Bidgoli, SJ | 1 |
| Pasin, L | 1 |
| Martinsen, K | 1 |
| Malaga, G | 1 |
| Myles, P | 1 |
| Acedillo, R | 1 |
| Roshanov, PS | 1 |
| Walsh, M | 1 |
| Dresser, G | 1 |
| Kumar, P | 1 |
| Painter, T | 1 |
| Biccard, B | 1 |
| Bergese, S | 1 |
| Srinathan, S | 1 |
| Chan, V | 1 |
| Mehra, B | 1 |
| Wijeysundera, DN | 1 |
| Forget, P | 1 |
| Kauh, CY | 1 |
| Bursztyn, LL | 1 |
| KREMER, H | 1 |
| Hess, RW | 1 |
| Taubert, KA | 1 |
| Ekelund, U | 1 |
| Björnberg, J | 1 |
| Mellander, S | 1 |
| Brazenor, RM | 1 |
| Bentley, GA | 1 |
| Sjöstrand, NO | 1 |
| Klinge, E | 1 |
| Rodriguez, S | 1 |
| Sanchez-Robio, F | 1 |
| Escanero, JF | 1 |
| Evans, RG | 1 |
| Hayes, IP | 1 |
| Ludbrook, J | 1 |
| Hosomi, H | 1 |
| Kawada, M | 1 |
| Yoshida, H | 1 |
| Motochigawa, H | 1 |
| Uemura, N | 1 |
| Nishida, Y | 1 |
| Morita, H | 1 |
| Filatov, AV | 1 |
| Kast, A | 1 |
| Muacevic, G | 1 |
| Kölbl, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Large, International, Placebo-controlled, Factorial Trial to Assess the Impact of Clonidine and Acetyl-salicylic Acid (ASA) in Patients Undergoing Noncardiac Surgery Who Are at Risk of a Perioperative Cardiovascular Event[NCT01082874] | Phase 3 | 10,010 participants (Actual) | Interventional | 2010-07-31 | Completed | ||
| Effect of Pre-operative Oral Steroids on Blood Loss in Endoscopic Sinus Surgery for Chronic Rhinosinusitis Without Polyps[NCT05095961] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2023-03-31 | Withdrawn (stopped due to Technical difficulties encountered with recording intraoperative blood loss; unable to proceed with study.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT01082874)
Timeframe: 30 days
| Intervention | participants (Number) |
|---|---|
| Active Clonidine and Active ASA | 173 |
| Active Clonidine and Placebo ASA | 194 |
| Placebo Clonidine and Active ASA | 178 |
| Placebo Clonidine and Placebo ASA | 161 |
3 trials available for clonidine and Bleeding
| Article | Year |
|---|---|
Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.
Topics: Aged; Antihypertensive Agents; Aspirin; Biomarkers; Clonidine; Drug Administration Schedule; Drug Th | 2018 |
Improved quality of surgical field during endoscopic sinus surgery after clonidine premedication--a pilot study.
Topics: Adult; Arterial Pressure; Chronic Disease; Clonidine; Endoscopy; Female; Heart Rate; Hemodynamics; H | 2014 |
Perioperative aspirin and clonidine and risk of acute kidney injury: a randomized clinical trial.
Topics: Acute Kidney Injury; Administration, Cutaneous; Administration, Oral; Adrenergic alpha-2 Receptor Ag | 2014 |
13 other studies available for clonidine and Bleeding
| Article | Year |
|---|---|
The Influence of Xylazine and Clonidine on Lung Ultrasound-Induced Pulmonary Capillary Hemorrhage in Spontaneously Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Capillaries; Clonidine; Hemorrhage; Hypertension; Lung; Male; Rats | 2021 |
Positive Apraclonidine Test in Horner Syndrome Caused by Thalamic Hemorrhage.
Topics: Aged; Clonidine; Diagnostic Techniques, Ophthalmological; Hemorrhage; Horner Syndrome; Humans; Magne | 2015 |
[On the histomorphology of the endometrium in functional hemorrhage following peroral administration of St 155-Oe].
Topics: Clonidine; Endometrium; Estradiol; Female; Hemorrhage; Humans; Progesterone; Uterine Hemorrhage | 1963 |
Increased incidence of death during warming in hypertensive rats treated with clonidine--possible lung pathology involvement.
Topics: Animals; Blood Pressure; Body Temperature Regulation; Clonidine; Hemorrhage; Hot Temperature; Hypert | 1984 |
Alpha 2-adrenoceptor activation may trigger the increased production of endothelium-derived nitric oxide in skeletal muscle during acute haemorrhage.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Cats; | 1998 |
Effects of alpha-agonists on circulatory responses to somatic afferent nerve stimulation.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Cats; Clonidine; Electric Stimulation; Female; H | 1978 |
Changes in penile volume during some cardiovascular reflexes and reactions in rabbit.
Topics: Animals; Arteries; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Ch | 1979 |
[The effect of clonidine on the renin production system].
Topics: Animals; Clonidine; Granuloma; Hemorrhage; Juxtaglomerular Apparatus; Rats; Renin | 1978 |
Effects of alpha-adrenoceptor antagonists and clonidine on the haemodynamic response to acute hypovolaemia in conscious rabbits.
Topics: Adrenergic alpha-Antagonists; Animals; Blood Pressure; Clonidine; Drug Interactions; Heart Rate; Hem | 1992 |
Alpha-agonist modifies baroreflex vasoconstriction by a postjunctional mechanism in dogs.
Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Dogs; Female; Hemorrhage; Hindlimb; M | 1989 |
[Participation of peptide mechanisms in physiological reactions of the cardiovascular system to hyperoxia].
Topics: Animals; Captopril; Cardiovascular Physiological Phenomena; Cardiovascular System; Clonidine; Enzyme | 1985 |
Reversible pulmonary changes in rats dosed intravenously with imidazoles.
Topics: Animals; Clonidine; Dose-Response Relationship, Drug; Female; Hemorrhage; Hemosiderosis; Imidazoles; | 1986 |
[Experiences with clonidine in hemorrhagic glaucoma in clinical practice].
Topics: Clonidine; Glaucoma; Hemorrhage; Humans | 1974 |